-
1
-
-
33646146498
-
Stromal niches, plasma cell differentiation and survival
-
Moser, K., Tokoyoda, K., Radbruch, A., MacLennan, I. & Manz, R. A. Stromal niches, plasma cell differentiation and survival. Curr. Opin. Immunol. 18, 265-270 (2006).
-
(2006)
Curr. Opin. Immunol.
, vol.18
, pp. 265-270
-
-
Moser, K.1
Tokoyoda, K.2
Radbruch, A.3
MacLennan, I.4
Manz, R.A.5
-
2
-
-
77649190767
-
Organization of immunological memory by bone marrow stroma
-
Tokoyoda, K., Hauser, A. E., Nakayama, T. & Radbruch, A. Organization of immunological memory by bone marrow stroma. Nat. Rev. Immunol. 10, 193-200 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 193-200
-
-
Tokoyoda, K.1
Hauser, A.E.2
Nakayama, T.3
Radbruch, A.4
-
3
-
-
75049085147
-
Osteoimmunology and the effects of the immune system on bone
-
Takayanagi, H. Osteoimmunology and the effects of the immune system on bone. Nat. Rev. Rheumatol. 5, 667-676 (2009).
-
(2009)
Nat. Rev. Rheumatol.
, vol.5
, pp. 667-676
-
-
Takayanagi, H.1
-
4
-
-
45149127782
-
Osteoimmunology: Interactions of the bone and immune system
-
Lorenzo, J., Horowitz, M. & Choi, Y. Osteoimmunology: interactions of the bone and immune system. Endocr. Rev. 29, 403-440 (2008).
-
(2008)
Endocr. Rev.
, vol.29
, pp. 403-440
-
-
Lorenzo, J.1
Horowitz, M.2
Choi, Y.3
-
5
-
-
34548494841
-
Osteoimmunology: A view from the bone
-
David, J. P. Osteoimmunology: a view from the bone. Adv. Immunol. 95, 149-165 (2007).
-
(2007)
Adv. Immunol.
, vol.95
, pp. 149-165
-
-
David, J.P.1
-
6
-
-
34249720998
-
Cytokines in the pathogenesis of rheumatoid arthritis
-
McInnes, I. B. & Schett, G. Cytokines in the pathogenesis of rheumatoid arthritis. Nat. Rev. Immunol. 7, 429-442 (2007).
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 429-442
-
-
McInnes, I.B.1
Schett, G.2
-
7
-
-
71849093619
-
Transcriptional networks controlling skeletal development
-
Hartmann, C. Transcriptional networks controlling skeletal development. Curr. Opin. Genet. Dev. 19, 437-443 (2009).
-
(2009)
Curr. Opin. Genet. Dev.
, vol.19
, pp. 437-443
-
-
Hartmann, C.1
-
8
-
-
70350244550
-
Genetic control of bone formation
-
Karsenty, G., Kronenberg, H. M. & Settembre, C. Genetic control of bone formation. Annu. Rev. Cell Dev. Biol. 25, 629-648 (2009).
-
(2009)
Annu. Rev. Cell. Dev. Biol.
, vol.25
, pp. 629-648
-
-
Karsenty, G.1
Kronenberg, H.M.2
Settembre, C.3
-
9
-
-
73349110430
-
Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis
-
Takada, I., Kouzmenko, A. P. & Kato, S. Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis. Nat. Rev. Rheumatol. 5, 442-447 (2009).
-
(2009)
Nat. Rev. Rheumatol.
, vol.5
, pp. 442-447
-
-
Takada, I.1
Kouzmenko, A.P.2
Kato, S.3
-
10
-
-
0043267732
-
Genetic regulation of osteoclast development and function
-
Teitelbaum, S. L. & Ross, F. P. Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4, 638-649 (2003).
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 638-649
-
-
Teitelbaum, S.L.1
Ross, F.P.2
-
11
-
-
0037673945
-
Osteoclast differentiation and activation
-
Boyle, W. J., Simonet, W. S. & Lacey, D. L. Osteoclast differentiation and activation. Nature 423, 337-342 (2003).
-
(2003)
Nature
, vol.423
, pp. 337-342
-
-
Boyle, W.J.1
Simonet, W.S.2
Lacey, D.L.3
-
12
-
-
42749088910
-
Osteoclast-osteoblast communication
-
Matsuo, K. & Irie, N. Osteoclast-osteoblast communication. Arch. Biochem. Biophys. 473, 201-209 (2008).
-
(2008)
Arch. Biochem. Biophys.
, vol.473
, pp. 201-209
-
-
Matsuo, K.1
Irie, N.2
-
13
-
-
30644469500
-
RANKL-RANK signaling in osteoclastogenesis and bone disease
-
Wada, T., Nakashima, T., Hiroshi, N. & Penninger, J. M. RANKL-RANK signaling in osteoclastogenesis and bone disease. Trends Mol. Med. 12, 17-25 (2006).
-
(2006)
Trends Mol. Med.
, vol.12
, pp. 17-25
-
-
Wada, T.1
Nakashima, T.2
Hiroshi, N.3
Penninger, J.M.4
-
14
-
-
16644399496
-
Secreted frizzled-related protein-1 inhibits RANKL-dependent osteoclast formation
-
Häusler, K. D. et al. Secreted frizzled-related protein-1 inhibits RANKL-dependent osteoclast formation. J. Bone Miner. Res. 19, 1873-1881 (2004).
-
(2004)
J. Bone Miner. Res.
, vol.19
, pp. 1873-1881
-
-
Häusler, K.D.1
-
15
-
-
33746528704
-
Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis
-
Zhao, C. et al. Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. Cell Metab. 4, 111-121 (2006).
-
(2006)
Cell. Metab.
, vol.4
, pp. 111-121
-
-
Zhao, C.1
-
16
-
-
0031439265
-
TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor
-
Wong, B. R. et al. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J. Exp. Med. 186, 2075-2080 (1997).
-
(1997)
J. Exp. Med.
, vol.186
, pp. 2075-2080
-
-
Wong, B.R.1
-
17
-
-
0033104614
-
TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells
-
Josien, R., Wong, B. R., Li, H. L., Steinman, R. M. & Choi, Y. TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells. J. Immunol. 162, 2562-2568 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 2562-2568
-
-
Josien, R.1
Wong, B.R.2
Li, H.L.3
Steinman, R.M.4
Choi, Y.5
-
18
-
-
37149026641
-
Treg cells suppress osteoclast formation: A new link between the immune system and bone
-
Zaiss, M. M. et al. Treg cells suppress osteoclast formation: a new link between the immune system and bone. Arthritis Rheum. 56, 4104-4112 (2007).
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 4104-4112
-
-
Zaiss, M.M.1
-
19
-
-
0034735773
-
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma
-
Takayanagi, H. et al. T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma. Nature 408, 600-605 (2000).
-
(2000)
Nature
, vol.408
, pp. 600-605
-
-
Takayanagi, H.1
-
20
-
-
0034992555
-
IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaB
-
Abu-Amer, Y. IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaB. J. Clin. Invest. 107, 1375-1385 (2001).
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1375-1385
-
-
Abu-Amer, Y.1
-
21
-
-
0037155165
-
Interleukin-4 reversibly inhibits osteoclastogenesis via inhibition of NF-kappa B and mitogen-activated protein kinase signaling
-
Wei, S., Wang, M. W., Teitelbaum, S. L. & Ross, F. P. Interleukin-4 reversibly inhibits osteoclastogenesis via inhibition of NF-kappa B and mitogen-activated protein kinase signaling. J. Biol. Chem. 277, 6622-6630 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6622-6630
-
-
Wei, S.1
Wang, M.W.2
Teitelbaum, S.L.3
Ross, F.P.4
-
22
-
-
0042744757
-
IL-4 suppresses osteoclast development and mature osteoclast function by a STAT6-dependent mechanism: Irreversible inhibition of the differentiation program activated by RANKL
-
Moreno, J. L., Kaczmarek, M., Keegan, A. D. & Tondravi, M. IL-4 suppresses osteoclast development and mature osteoclast function by a STAT6-dependent mechanism: irreversible inhibition of the differentiation program activated by RANKL. Blood 102, 1078-1086 (2003).
-
(2003)
Blood
, vol.102
, pp. 1078-1086
-
-
Moreno, J.L.1
Kaczmarek, M.2
Keegan, A.D.3
Tondravi, M.4
-
23
-
-
47249103596
-
CTLA-4 directly inhibits osteoclast formation
-
Axmann, R. et al. CTLA-4 directly inhibits osteoclast formation. Ann. Rheum. Dis. 67, 1603-1609 (2008).
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 1603-1609
-
-
Axmann, R.1
-
24
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
Sato, K. et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med. 203, 2673-2682 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2673-2682
-
-
Sato, K.1
-
25
-
-
34247882571
-
Human CD4+CD25+ regulatory T cells inhibit the differentiation of osteoclasts from peripheral blood mononuclear cells
-
Kim, Y. G. et al. Human CD4+CD25+ regulatory T cells inhibit the differentiation of osteoclasts from peripheral blood mononuclear cells. Biochem. Biophys. Res. Commun. 357, 1046-1052 (2007).
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.357
, pp. 1046-1052
-
-
Kim, Y.G.1
-
26
-
-
0034947297
-
Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8 (+) T cells
-
Choi, Y. et al. Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8 (+) T cells. Eur. J. Immunol. 31, 2179-2188 (2001).
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 2179-2188
-
-
Choi, Y.1
-
27
-
-
33748686237
-
Activated T lymphocytes suppress osteoclastogenesis by diverting early monocyte/macrophage progenitor lineage commitment towards dendritic cell differentiation through down-regulation of receptor activator of nuclear factor-kappaB and c-Fos
-
Grcevic, D. et al. Activated T lymphocytes suppress osteoclastogenesis by diverting early monocyte/macrophage progenitor lineage commitment towards dendritic cell differentiation through down-regulation of receptor activator of nuclear factor-kappaB and c-Fos. Clin. Exp. Immunol. 146, 146-158 (2006).
-
(2006)
Clin. Exp. Immunol.
, vol.146
, pp. 146-158
-
-
Grcevic, D.1
-
28
-
-
77955373402
-
Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation
-
Zaiss, M. M. et al. Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation. Arthritis Rheum. 62, 2328-2338 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2328-2338
-
-
Zaiss, M.M.1
-
29
-
-
34247323904
-
B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo
-
Li, Y. et al. B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Blood 109, 3839-3848 (2007).
-
(2007)
Blood
, vol.109
, pp. 3839-3848
-
-
Li, Y.1
-
30
-
-
48149095459
-
T cells potentiate PTH-induced cortical bone loss through CD40L signaling
-
Gao, Y. et al. T cells potentiate PTH-induced cortical bone loss through CD40L signaling. Cell Metab. 8, 132-145 (2008).
-
(2008)
Cell. Metab.
, vol.8
, pp. 132-145
-
-
Gao, Y.1
-
31
-
-
33845981069
-
IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigendriven T cell activation
-
Gao, Y. et al. IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigendriven T cell activation. J. Clin. Invest. 117, 122-132 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 122-132
-
-
Gao, Y.1
-
32
-
-
37449014336
-
Bone remodeling, energy metabolism, and the molecular clock
-
Rosen, C. J. Bone remodeling, energy metabolism, and the molecular clock. Cell Metab. 7, 7-10 (2008).
-
(2008)
Cell. Metab.
, vol.7
, pp. 7-10
-
-
Rosen, C.J.1
-
34
-
-
58549099858
-
Bone and metabolism: A complex crosstalk
-
Lieben, L., Callewaert, F. & Bouillon, R. Bone and metabolism: a complex crosstalk. Horm. Res. 71 (Suppl. 1), 134-138 (2009).
-
(2009)
Horm. Res.
, vol.71
, Issue.1 SUPPL.
, pp. 134-138
-
-
Lieben, L.1
Callewaert, F.2
Bouillon, R.3
-
35
-
-
59449093033
-
The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity
-
Hinoi, E. et al. The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity. J. Cell Biol. 183, 1235-1242 (2008).
-
(2008)
J. Cell. Biol.
, vol.183
, pp. 1235-1242
-
-
Hinoi, E.1
-
36
-
-
70349226800
-
The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts
-
Yoshizawa, T. et al. The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts. J. Clin. Invest. 119, 2807-2817 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2807-2817
-
-
Yoshizawa, T.1
-
37
-
-
42449096306
-
Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
-
Ferron, M., Hinoi, E., Karsenty, G. & Ducy, P. Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proc. Natl Acad. Sci. USA 105, 5266-5270 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 5266-5270
-
-
Ferron, M.1
Hinoi, E.2
Karsenty, G.3
Ducy, P.4
-
38
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
-
Ducy, P. et al. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100, 197-207 (2000).
-
(2000)
Cell.
, vol.100
, pp. 197-207
-
-
Ducy, P.1
-
39
-
-
0036847619
-
Leptin regulates bone formation via the sympathetic nervous system
-
Takeda, S. et al. Leptin regulates bone formation via the sympathetic nervous system. Cell 111, 305-317 (2002).
-
(2002)
Cell.
, vol.111
, pp. 305-317
-
-
Takeda, S.1
-
40
-
-
24144459585
-
The molecular clock mediates leptin-regulated bone formation
-
Fu, L., Patel, M. S., Bradley, A., Wagner, E. F. & Karsenty, G. The molecular clock mediates leptin-regulated bone formation. Cell 122, 803-815 (2005).
-
(2005)
Cell.
, vol.122
, pp. 803-815
-
-
Fu, L.1
Patel, M.S.2
Bradley, A.3
Wagner, E.F.4
Karsenty, G.5
-
41
-
-
24744438262
-
Transcriptional regulation of neuronal genes and its effect on neural functions: Transcriptional regulation of neuropeptide Y gene by leptin and its effect on feeding
-
Higuchi, H., Hasegawa, A. & Yamaguchi, T. Transcriptional regulation of neuronal genes and its effect on neural functions: transcriptional regulation of neuropeptide Y gene by leptin and its effect on feeding. J. Pharmacol. Sci. 98, 225-231 (2005).
-
(2005)
J. Pharmacol. Sci.
, vol.98
, pp. 225-231
-
-
Higuchi, H.1
Hasegawa, A.2
Yamaguchi, T.3
-
42
-
-
0029804743
-
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
-
Erickson, J. C., Hollopeter, G. & Palmiter, R. D. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 274, 1704-1707 (1996).
-
(1996)
Science
, vol.274
, pp. 1704-1707
-
-
Erickson, J.C.1
Hollopeter, G.2
Palmiter, R.D.3
-
43
-
-
0036212496
-
Hypothalamic Y2 receptors regulate bone formation
-
Baldock, P. A. et al. Hypothalamic Y2 receptors regulate bone formation. J. Clin. Invest. 109, 915-921 (2002).
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 915-921
-
-
Baldock, P.A.1
-
44
-
-
34547105098
-
Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis
-
Baldock, P. A. et al. Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis. J. Biol. Chem. 282, 19092-19102 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 19092-19102
-
-
Baldock, P.A.1
-
45
-
-
77949493813
-
Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight
-
Baldock, P. A. et al. Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight. PLoS ONE 4, e8415 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Baldock, P.A.1
-
46
-
-
34447116241
-
Neuropeptide Y acts directly in the periphery on fat tissue and mediates stressinduced obesity and metabolic syndrome
-
Kuo, L. E. et al. Neuropeptide Y acts directly in the periphery on fat tissue and mediates stressinduced obesity and metabolic syndrome. Nat. Med. 13, 803-811 (2007).
-
(2007)
Nat. Med.
, vol.13
, pp. 803-811
-
-
Kuo, L.E.1
-
47
-
-
25444468833
-
Hypothalamic control of bone formation: Distinct actions of leptin and y2 receptor pathways
-
Baldock, P. A. et al. Hypothalamic control of bone formation: distinct actions of leptin and y2 receptor pathways. J. Bone Miner. Res. 20, 1851-1857 (2005).
-
(2005)
J. Bone Miner. Res.
, vol.20
, pp. 1851-1857
-
-
Baldock, P.A.1
-
48
-
-
33749248697
-
Hypothalamic regulation of cortical bone mass: Opposing activity of Y2 receptor and leptin pathways
-
Baldock, P. A. et al. Hypothalamic regulation of cortical bone mass: opposing activity of Y2 receptor and leptin pathways. J. Bone Miner. Res. 21, 1600-1607 (2006).
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 1600-1607
-
-
Baldock, P.A.1
-
49
-
-
7044229277
-
Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway
-
Hanada, R. et al. Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway. Nat. Med. 10, 1067-1073 (2004).
-
(2004)
Nat. Med.
, vol.10
, pp. 1067-1073
-
-
Hanada, R.1
-
50
-
-
34948910681
-
Central control of bone remodeling by neuromedin U
-
Sato, S. et al. Central control of bone remodeling by neuromedin U. Nat. Med. 13, 1234-1240 (2007).
-
(2007)
Nat. Med.
, vol.13
, pp. 1234-1240
-
-
Sato, S.1
-
51
-
-
77956621348
-
Leptin functions peripherally to regulate differentiation of mesenchymal progenitor cells
-
Scheller, E. L. et al. Leptin functions peripherally to regulate differentiation of mesenchymal progenitor cells. Stem Cells 28, 1071-1080 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 1071-1080
-
-
Scheller, E.L.1
-
52
-
-
49349087458
-
Critical role of the hypothalamic-pituitary-thyroid axis in bone
-
Bassett, J. H. & Williams, G. R. Critical role of the hypothalamic-pituitary-thyroid axis in bone. Bone 43, 418-426 (2008).
-
(2008)
Bone
, vol.43
, pp. 418-426
-
-
Bassett, J.H.1
Williams, G.R.2
-
53
-
-
70449441060
-
Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity
-
Kunz, M. & Ibrahim, S. M. Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity. Mediators Inflamm. 2009, 979258 (2009).
-
(2009)
Mediators Inflamm.
, vol.2009
, pp. 979258
-
-
Kunz, M.1
Ibrahim, S.M.2
-
54
-
-
55649105547
-
Distinct monocyte geneexpression profiles in autoimmune diabetes
-
Padmos, R. C. et al. Distinct monocyte geneexpression profiles in autoimmune diabetes. Diabetes 57, 2768-2773 (2008).
-
(2008)
Diabetes
, vol.57
, pp. 2768-2773
-
-
Padmos, R.C.1
-
55
-
-
33644756809
-
Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes
-
Devaraj, S. et al. Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes. Diabetes 55, 774-779 (2006).
-
(2006)
Diabetes
, vol.55
, pp. 774-779
-
-
Devaraj, S.1
-
56
-
-
77951651191
-
An inflammatory gene-expression fingerprint in monocytes of autoimmune thyroid disease patients
-
van der Heul-Nieuwenhuijsen, L. et al. An inflammatory gene-expression fingerprint in monocytes of autoimmune thyroid disease patients. J. Clin. Endocrinol. Metab. 95, 1962-1971 (2010).
-
(2010)
J. Clin. Endocrinol. Metab.
, vol.95
, pp. 1962-1971
-
-
Van Der Heul-Nieuwenhuijsen, L.1
-
57
-
-
70349883835
-
Osteoporosis associated with neutralizing autoantibodies against osteoprotegerin
-
Riches, P. L. et al. Osteoporosis associated with neutralizing autoantibodies against osteoprotegerin. N. Engl. J. Med. 361, 1459-1465 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1459-1465
-
-
Riches, P.L.1
-
58
-
-
58149388693
-
Bone inflammation and altered gene expression with type I diabetes early onset
-
Motyl, K. J. et al. Bone inflammation and altered gene expression with type I diabetes early onset. J. Cell Physiol. 218, 575-583 (2009).
-
(2009)
J. Cell. Physiol.
, vol.218
, pp. 575-583
-
-
Motyl, K.J.1
-
59
-
-
36549035222
-
Immune regulation in psoriasis and psoriatic arthritis-recent developments
-
Hueber, A. J. & McInnes, I. B. Immune regulation in psoriasis and psoriatic arthritis-recent developments. Immunol. Lett. 114, 59-65 (2007).
-
(2007)
Immunol. Lett.
, vol.114
, pp. 59-65
-
-
Hueber, A.J.1
McInnes, I.B.2
-
60
-
-
25144497098
-
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun. proteins
-
Zenz, R. et al. Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun. proteins. Nature 437, 369-375 (2005).
-
(2005)
Nature
, vol.437
, pp. 369-375
-
-
Zenz, R.1
-
61
-
-
46749125294
-
Shifting the imbalance from Th1/Th2 to Th17/treg: The changing rheumatoid arthritis paradigm
-
Boissier, M. C., Assier, E., Falgarone, G. & Bessis, N. Shifting the imbalance from Th1/Th2 to Th17/treg: the changing rheumatoid arthritis paradigm. Joint Bone Spine 75, 373-375 (2008).
-
(2008)
Joint Bone Spine
, vol.75
, pp. 373-375
-
-
Boissier, M.C.1
Assier, E.2
Falgarone, G.3
Bessis, N.4
-
62
-
-
65849467800
-
Th17 and regulatory T cells: Rebalancing pro-and antiinflammatory forces in autoimmune arthritis
-
Nistala, K. & Wedderburn, L. R. Th17 and regulatory T cells: rebalancing pro-and antiinflammatory forces in autoimmune arthritis. Rheumatology (Oxford) 48, 602-606 (2009).
-
(2009)
Rheumatology (Oxford)
, vol.48
, pp. 602-606
-
-
Nistala, K.1
Wedderburn, L.R.2
-
63
-
-
77953639101
-
Regulatory T cells protect from local and systemic bone destruction in arthritis
-
Zaiss, M. M. et al. Regulatory T cells protect from local and systemic bone destruction in arthritis. J. Immunol. 184, 7238-7246 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 7238-7246
-
-
Zaiss, M.M.1
-
64
-
-
0026039673
-
Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
-
Keffer, J. et al. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J. 10, 4025-4031 (1991).
-
(1991)
EMBO J.
, vol.10
, pp. 4025-4031
-
-
Keffer, J.1
-
65
-
-
0038342686
-
Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice
-
Schett, G. et al. Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice. Arthritis Rheum. 48, 2042-2051 (2003).
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 2042-2051
-
-
Schett, G.1
-
67
-
-
67649364114
-
The role of inflammation in insulitis and beta-cell loss in type 1 diabetes
-
Eizirik, D. L., Colli, M. L. & Ortis, F. The role of inflammation in insulitis and beta-cell loss in type 1 diabetes. Nat. Rev. Endocrinol. 5, 219-226 (2009).
-
(2009)
Nat. Rev. Endocrinol.
, vol.5
, pp. 219-226
-
-
Eizirik, D.L.1
Colli, M.L.2
Ortis, F.3
-
68
-
-
53849120957
-
Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: From epidemiology to mechanisms
-
Huber, A., Menconi, F., Corathers, S., Jacobson, E. M. & Tomer, Y. Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms. Endocr. Rev. 29, 697-725 (2008).
-
(2008)
Endocr. Rev.
, vol.29
, pp. 697-725
-
-
Huber, A.1
Menconi, F.2
Corathers, S.3
Jacobson, E.M.4
Tomer, Y.5
-
69
-
-
44649198581
-
The molecular genetics of type 1 diabetes: New genes and emerging mechanisms
-
Ounissi-Benkalha, H. & Polychronakos, C. The molecular genetics of type 1 diabetes: new genes and emerging mechanisms. Trends Mol. Med. 14, 268-275 (2008).
-
(2008)
Trends Mol. Med.
, vol.14
, pp. 268-275
-
-
Ounissi-Benkalha, H.1
Polychronakos, C.2
-
70
-
-
64749116743
-
Genetics of type 1A diabetes
-
Concannon, P., Rich, S. S. & Nepom, G. T. Genetics of type 1A diabetes. N. Engl. J. Med. 360, 1646-1654 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1646-1654
-
-
Concannon, P.1
Rich, S.S.2
Nepom, G.T.3
-
71
-
-
43249096519
-
Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes
-
Pirot, P., Cardozo, A. K. & Eizirik, D. L. Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes. Arq. Bras. Endocrinol. Metabol. 52, 156-165 (2008).
-
(2008)
Arq. Bras. Endocrinol. Metabol.
, vol.52
, pp. 156-165
-
-
Pirot, P.1
Cardozo, A.K.2
Eizirik, D.L.3
-
72
-
-
0344736959
-
Diabetes mellitus: Does it affect bone?
-
Schwartz, A. V. Diabetes mellitus: does it affect bone? Calcif. Tissue Int. 73, 515-519 (2003).
-
(2003)
Calcif. Tissue Int.
, vol.73
, pp. 515-519
-
-
Schwartz, A.V.1
-
73
-
-
44849133629
-
Osteoporosis among patients with type 1 and type 2 diabetes
-
Räkel, A., Sheehy, O., Rahme, E. & LeLorier, J. Osteoporosis among patients with type 1 and type 2 diabetes. Diabetes Metab. 34, 193-205 (2008).
-
(2008)
Diabetes Metab.
, vol.34
, pp. 193-205
-
-
Räkel, A.1
Sheehy, O.2
Rahme, E.3
LeLorier, J.4
-
74
-
-
27144448386
-
Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues
-
Thrailkill, K. M., Lumpkin, C. K. Jr, Bunn, R. C., Kemp, S. F. & Fowlkes, J. L. Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues. Am. J. Physiol. Endocrinol. Metab. 289, E735-E745 (2005).
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.289
-
-
Thrailkill, K.M.1
Lumpkin Jr., C.K.2
Bunn, R.C.3
Kemp, S.F.4
Fowlkes, J.L.5
-
75
-
-
36849045166
-
Understanding the pathology and mechanisms of type I diabetic bone loss
-
McCabe, L. R. Understanding the pathology and mechanisms of type I diabetic bone loss. J. Cell Biochem. 102, 1343-1357 (2007).
-
(2007)
J. Cell. Biochem.
, vol.102
, pp. 1343-1357
-
-
McCabe, L.R.1
-
76
-
-
33845883071
-
Bone loss and increased bone adiposity in spontaneous and pharmacologically induced diabetic mice
-
Botolin, S. & McCabe, L. R. Bone loss and increased bone adiposity in spontaneous and pharmacologically induced diabetic mice. Endocrinology 148, 198-205 (2007).
-
(2007)
Endocrinology
, vol.148
, pp. 198-205
-
-
Botolin, S.1
McCabe, L.R.2
-
77
-
-
34547579253
-
Type I diabetic bone phenotype is location but not gender dependent
-
Martin, L. M. & McCabe, L. R. Type I diabetic bone phenotype is location but not gender dependent. Histochem. Cell Biol. 128, 125-133 (2007).
-
(2007)
Histochem. Cell. Biol.
, vol.128
, pp. 125-133
-
-
Martin, L.M.1
McCabe, L.R.2
-
78
-
-
25844492123
-
Bone formation is impaired in a model of type 1 diabetes
-
Thrailkill, K. M. et al. Bone formation is impaired in a model of type 1 diabetes. Diabetes 54, 2875-2881 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 2875-2881
-
-
Thrailkill, K.M.1
-
79
-
-
33751523583
-
Normal bone density obtained in the absence of insulin receptor expression in bone
-
Irwin, R., Lin, H. v., Motyl, K. J. & McCabe, L. R. Normal bone density obtained in the absence of insulin receptor expression in bone. Endocrinology 147, 5760-5767 (2006).
-
(2006)
Endocrinology
, vol.147
, pp. 5760-5767
-
-
Irwin, R.1
Lin, H.V.2
Motyl, K.J.3
McCabe, L.R.4
-
80
-
-
77955082747
-
Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition
-
Fulzele, K. et al. Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition. Cell 142, 309-319 (2010).
-
(2010)
Cell.
, vol.142
, pp. 309-319
-
-
Fulzele, K.1
-
81
-
-
56749165325
-
IGF-1 and IGF-binding proteins and bone mass, geometry, and strength: Relation to metabolic control in adolescent girls with type 1 diabetes
-
Moyer-Mileur, L. J., Slater, H., Jordan, K. C. & Murray, M. A. IGF-1 and IGF-binding proteins and bone mass, geometry, and strength: relation to metabolic control in adolescent girls with type 1 diabetes. J. Bone Miner. Res. 23, 1884-1891 (2008).
-
(2008)
J. Bone Miner. Res.
, vol.23
, pp. 1884-1891
-
-
Moyer-Mileur, L.J.1
Slater, H.2
Jordan, K.C.3
Murray, M.A.4
-
82
-
-
70349316243
-
Central leptin gene therapy ameliorates diabetes type 1 and 2 through two independent hypothalamic relays; a benefit beyond weight and appetite regulation
-
Kalra, S. P. Central leptin gene therapy ameliorates diabetes type 1 and 2 through two independent hypothalamic relays; a benefit beyond weight and appetite regulation. Peptides 30, 1957-1963 (2009).
-
(2009)
Peptides
, vol.30
, pp. 1957-1963
-
-
Kalra, S.P.1
-
83
-
-
19044381754
-
Leptin treatment induces loss of bone marrow adipocytes and increases bone formation in leptin-deficient ob/ob mice
-
Hamrick, M. W. et al. Leptin treatment induces loss of bone marrow adipocytes and increases bone formation in leptin-deficient ob/ob mice. J. Bone Miner. Res. 20, 994-1001 (2005).
-
(2005)
J. Bone Miner. Res.
, vol.20
, pp. 994-1001
-
-
Hamrick, M.W.1
-
84
-
-
33750506697
-
Inhibition of PPARgamma prevents type I diabetic bone marrow adiposity but not bone loss
-
Botolin, S. & McCabe, L. R. Inhibition of PPARgamma prevents type I diabetic bone marrow adiposity but not bone loss. J. Cell Physiol. 209, 967-976 (2006).
-
(2006)
J. Cell. Physiol.
, vol.209
, pp. 967-976
-
-
Botolin, S.1
McCabe, L.R.2
-
85
-
-
58149263759
-
Leptin treatment prevents type I diabetic marrow adiposity but not bone loss in mice
-
Motyl, K. J. & McCabe, L. R. Leptin treatment prevents type I diabetic marrow adiposity but not bone loss in mice. J. Cell Physiol. 218, 376-384 (2009).
-
(2009)
J. Cell. Physiol.
, vol.218
, pp. 376-384
-
-
Motyl, K.J.1
McCabe, L.R.2
-
86
-
-
74849134104
-
Type 1 diabetes and autoimmune polyglandular syndrome: A clinical review
-
van den Driessche, A., Eenkhoorn, V., Van Gaal, L. & De Block, C. Type 1 diabetes and autoimmune polyglandular syndrome: a clinical review. Neth. J. Med. 67, 376-387 (2009).
-
(2009)
Neth. J. Med.
, vol.67
, pp. 376-387
-
-
Van Den Driessche, A.1
Eenkhoorn, V.2
Van Gaal, L.3
Block, C.4
-
88
-
-
0035986943
-
Fractures in patients with hyperthyroidism and hypothyroidism: A nationwide follow-up study in 16,249 patients
-
Vestergaard, P. & Mosekilde, L. Fractures in patients with hyperthyroidism and hypothyroidism: a nationwide follow-up study in 16, 249 patients. Thyroid 12, 411-419 (2002). (Pubitemid 34602601)
-
(2002)
Thyroid
, vol.12
, Issue.5
, pp. 411-419
-
-
Vestergaard, P.1
Mosekilde, L.2
-
89
-
-
10744226715
-
TSH is a negative regulator of skeletal remodeling
-
Abe, E. et al. TSH is a negative regulator of skeletal remodeling. Cell 115, 151-162 (2003).
-
(2003)
Cell.
, vol.115
, pp. 151-162
-
-
Abe, E.1
-
90
-
-
38749088288
-
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism
-
Bassett, J. H. et al. A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. Mol. Endocrinol. 22, 501-512 (2008).
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 501-512
-
-
Bassett, J.H.1
-
91
-
-
28544448518
-
Rheumatic diseases: The effects of inflammation on bone
-
Walsh, N. C., Crotti, T. N., Goldring, S. R. & Gravallese, E. M. Rheumatic diseases: the effects of inflammation on bone. Immunol. Rev. 208, 228-251 (2005).
-
(2005)
Immunol. Rev.
, vol.208
, pp. 228-251
-
-
Walsh, N.C.1
Crotti, T.N.2
Goldring, S.R.3
Gravallese, E.M.4
-
92
-
-
70350604246
-
Osteoporosis in patients with systemic lupus erythematosus
-
García-Carrasco, M. et al. Osteoporosis in patients with systemic lupus erythematosus. Isr. Med. Assoc. J. 11, 486-491 (2009).
-
(2009)
Isr. Med. Assoc. J.
, vol.11
, pp. 486-491
-
-
García-Carrasco, M.1
-
93
-
-
34247095201
-
Epidemiology of osteoporosis in rheumatic diseases
-
Sinigaglia, L., Varenna, M., Girasole, G. & Bianchi, G. Epidemiology of osteoporosis in rheumatic diseases. Rheum. Dis. Clin. North Am. 32, 631-658 (2006).
-
(2006)
Rheum. Dis. Clin. North Am.
, vol.32
, pp. 631-658
-
-
Sinigaglia, L.1
Varenna, M.2
Girasole, G.3
Bianchi, G.4
-
94
-
-
41749115914
-
Review: Vitamin D, immunity and lupus
-
Cutolo, M. & Otsa, K. Review: vitamin D, immunity and lupus. Lupus 17, 6-10 (2008).
-
(2008)
Lupus
, vol.17
, pp. 6-10
-
-
Cutolo, M.1
Otsa, K.2
-
95
-
-
34548400388
-
Bone status in juvenile systemic lupus erythematosus
-
Lilleby, V. Bone status in juvenile systemic lupus erythematosus. Lupus 16, 580-586 (2007).
-
(2007)
Lupus
, vol.16
, pp. 580-586
-
-
Lilleby, V.1
|