메뉴 건너뛰기




Volumn 4, Issue 12, 2009, Pages

Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight

Author keywords

[No Author keywords available]

Indexed keywords

NEUROPEPTIDE Y; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2;

EID: 77949493813     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008415     Document Type: Article
Times cited : (142)

References (26)
  • 1
    • 0027787677 scopus 로고
    • Characterization of beta-adrenergic receptors on rat and human osteoblast-like cells and demonstration that beta-receptor agonists can stimulate bone resorption in organ culture
    • Moore RE, Smith CK, Bailey CS, Voelkel EF, Tashjian AH (1993) Characterization of beta-adrenergic receptors on rat and human osteoblast- like cells and demonstration that beta-receptor agonists can stimulate bone resorption in organ culture. Bone Miner 23: 301-315.
    • (1993) Bone Miner , vol.23 , pp. 301-315
    • Moore, R.E.1    Smith, C.K.2    Bailey, C.S.3    Voelkel, E.F.4    Tashjian, A.H.5
  • 2
    • 0031981749 scopus 로고    scopus 로고
    • Formoterol and isoproterenol induce c-fos gene expression in osteoblast-like cells by activating beta2-adrenergic receptors
    • Kellenberger S, Muller K, Richener H, Bilbe G (1998) Formoterol and isoproterenol induce c-fos gene expression in osteoblast-like cells by activating beta2-adrenergic receptors. Bone 22: 471-478.
    • (1998) Bone , vol.22 , pp. 471-478
    • Kellenberger, S.1    Muller, K.2    Richener, H.3    Bilbe, G.4
  • 3
    • 0036847619 scopus 로고    scopus 로고
    • Leptin regulates bone formation via the sympathetic nervous system
    • Takeda S, Elefteriou F, Levasseur R, Liu X, Zhao L, et al. (2002) Leptin regulates bone formation via the sympathetic nervous system. Cell 111: 305-317.
    • (2002) Cell , vol.111 , pp. 305-317
    • Takeda, S.1    Elefteriou, F.2    Levasseur, R.3    Liu, X.4    Zhao, L.5
  • 4
    • 0022873040 scopus 로고
    • Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity
    • Stanley BG, Kyrkouli SE, Lampert S, Leibowitz SF (1986) Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity. Peptides 7: 1189-1192.
    • (1986) Peptides , vol.7 , pp. 1189-1192
    • Stanley, B.G.1    Kyrkouli, S.E.2    Lampert, S.3    Leibowitz, S.F.4
  • 5
    • 0029804743 scopus 로고    scopus 로고
    • Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
    • Erickson JC, Hollopeter G, Palmiter RD (1996) Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 274: 1704-1707.
    • (1996) Science , vol.274 , pp. 1704-1707
    • Erickson, J.C.1    Hollopeter, G.2    Palmiter, R.D.3
  • 7
    • 0030840674 scopus 로고    scopus 로고
    • Y-receptor subtypes-how many more?
    • Blomqvist AG, Herzog H (1997) Y-receptor subtypes-how many more? Trends Neurosci 20: 294-298.
    • (1997) Trends Neurosci , vol.20 , pp. 294-298
    • Blomqvist, A.G.1    Herzog, H.2
  • 8
    • 25444468833 scopus 로고    scopus 로고
    • Hypothalamic control of bone formation: Distinct actions of leptin and y2 receptor pathways
    • Baldock PA, Sainsbury A, Allison S, Lin EJ, Couzens M, et al. (2005) Hypothalamic control of bone formation: distinct actions of leptin and y2 receptor pathways. J Bone Miner Res 20: 1851-1857.
    • (2005) J Bone Miner Res , vol.20 , pp. 1851-1857
    • Baldock, P.A.1    Sainsbury, A.2    Allison, S.3    Lin, E.J.4    Couzens, M.5
  • 9
    • 33749248697 scopus 로고    scopus 로고
    • Hypothalamic regulation of cortical bone mass: Opposing activity of Y2 receptor and leptin pathways
    • Baldock PA, Allison S, McDonald MM, Sainsbury A, Enriquez RF, et al. (2006) Hypothalamic regulation of cortical bone mass: opposing activity of Y2 receptor and leptin pathways. J Bone Miner Res 21: 1600-1607.
    • (2006) J Bone Miner Res , vol.21 , pp. 1600-1607
    • Baldock, P.A.1    Allison, S.2    McDonald, M.M.3    Sainsbury, A.4    Enriquez, R.F.5
  • 10
    • 34547105098 scopus 로고    scopus 로고
    • Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis
    • Baldock PA, Allison SJ, Lundberg P, Lee NJ, Slack K, et al. (2007) Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis. J Biol Chem 282: 19092-19102.
    • (2007) J Biol Chem , vol.282 , pp. 19092-19102
    • Baldock, P.A.1    Allison, S.J.2    Lundberg, P.3    Lee, N.J.4    Slack, K.5
  • 11
    • 33747646239 scopus 로고    scopus 로고
    • Conditional deletion of hypothalamic Y2 receptors reverts gonadectomy- induced bone loss in adult mice
    • Allison SJ, Baldock P, Sainsbury A, Enriquez R, Lee NJ, et al. (2006) Conditional deletion of hypothalamic Y2 receptors reverts gonadectomy- induced bone loss in adult mice. J Biol Chem 281: 23436-23444.
    • (2006) J Biol Chem , vol.281 , pp. 23436-23444
    • Allison, S.J.1    Baldock, P.2    Sainsbury, A.3    Enriquez, R.4    Lee, N.J.5
  • 12
    • 0141737573 scopus 로고    scopus 로고
    • Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
    • Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, et al. (2000) Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100: 197-207.
    • (2000) Cell , vol.100 , pp. 197-207
    • Ducy, P.1    Amling, M.2    Takeda, S.3    Priemel, M.4    Schilling, A.F.5
  • 13
    • 0042922594 scopus 로고    scopus 로고
    • Monosodium glutamate-sensitive hypothalamic neurons contribute to the control of bone mass
    • Elefteriou F, Takeda S, Liu X, Armstrong D, Karsenty G (2003) Monosodium glutamate-sensitive hypothalamic neurons contribute to the control of bone mass. Endocrinology 144: 3842-3847.
    • (2003) Endocrinology , vol.144 , pp. 3842-3847
    • Elefteriou, F.1    Takeda, S.2    Liu, X.3    Armstrong, D.4    Karsenty, G.5
  • 14
    • 43149117061 scopus 로고    scopus 로고
    • Relationships between fat and bone
    • Reid IR (2008) Relationships between fat and bone. Osteoporos Int 19: 595-606.
    • (2008) Osteoporos Int , vol.19 , pp. 595-606
    • Reid, I.R.1
  • 15
    • 0028924906 scopus 로고
    • Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression
    • Sipols AJ, Baskin DG, Schwartz MW (1995) Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression. Diabetes 44: 147-151.
    • (1995) Diabetes , vol.44 , pp. 147-151
    • Sipols, A.J.1    Baskin, D.G.2    Schwartz, M.W.3
  • 16
    • 0024471489 scopus 로고
    • Opposite effects of centrally administered neuropeptide Y (NPY) on locomotor activity of spontaneously hypertensive (SH) and normal rats
    • Heilig M, Vecsei L, Widerlov E (1989) Opposite effects of centrally administered neuropeptide Y (NPY) on locomotor activity of spontaneously hypertensive (SH) and normal rats. Acta Physiol Scand 137: 243-248.
    • (1989) Acta Physiol Scand , vol.137 , pp. 243-248
    • Heilig, M.1    Vecsei, L.2    Widerlov, E.3
  • 17
    • 50249185592 scopus 로고    scopus 로고
    • Functional adaptation to loading of a single bone is neuronally regulated and involves multiple bones
    • Sample SJ, Behan M, Smith L, Oldenhoff WE, Markel MD, et al. (2008) Functional adaptation to loading of a single bone is neuronally regulated and involves multiple bones. J Bone Miner Res 23: 1372-1381.
    • (2008) J Bone Miner Res , vol.23 , pp. 1372-1381
    • Sample, S.J.1    Behan, M.2    Smith, L.3    Oldenhoff, W.E.4    Markel, M.D.5
  • 18
    • 44449174547 scopus 로고    scopus 로고
    • Caloric restriction decreases cortical bone mass but spares trabecular bone in the mouse skeleton: Implications for the regulation of bone mass by body weight
    • Hamrick MW, Ding KH, Ponnala S, Ferrari SL, Isales CM (2008) Caloric restriction decreases cortical bone mass but spares trabecular bone in the mouse skeleton: implications for the regulation of bone mass by body weight. J Bone Miner Res 23: 870-878.
    • (2008) J Bone Miner Res , vol.23 , pp. 870-878
    • Hamrick, M.W.1    Ding, K.H.2    Ponnala, S.3    Ferrari, S.L.4    Isales, C.M.5
  • 19
    • 33645357530 scopus 로고    scopus 로고
    • Nutrition-related peptides and bone homeostasis
    • Reid IR, Cornish J, Baldock PA (2006) Nutrition-related peptides and bone homeostasis. J Bone Miner Res 21: 495-500.
    • (2006) J Bone Miner Res , vol.21 , pp. 495-500
    • Reid, I.R.1    Cornish, J.2    Baldock, P.A.3
  • 20
    • 70350159010 scopus 로고    scopus 로고
    • Neuropeptide Y is expressed by osteocytes and can inhibit osteoblastic activity
    • Igwe JC, Jiang X, Paic F, Ma L, Adams DJ, et al. (2009) Neuropeptide Y is expressed by osteocytes and can inhibit osteoblastic activity. J Cell Biochem.
    • (2009) J Cell Biochem
    • Igwe, J.C.1    Jiang, X.2    Paic, F.3    Ma, L.4    Adams, D.J.5
  • 21
    • 54049141743 scopus 로고    scopus 로고
    • Behavioural profile of a new mouse model for NPY deficiency
    • Karl T, Duffy L, Herzog H (2008) Behavioural profile of a new mouse model for NPY deficiency. Eur J Neurosci 28: 173-180.
    • (2008) Eur J Neurosci , vol.28 , pp. 173-180
    • Karl, T.1    Duffy, L.2    Herzog, H.3
  • 23
    • 15344347049 scopus 로고    scopus 로고
    • beta- Arrestin2 regulates the differential response of cortical and trabecular bone to intermittent PTH in female mice
    • Bouxsein ML, Pierroz DD, Glatt V, Goddard DS, Cavat F, et al. (2005) beta- Arrestin2 regulates the differential response of cortical and trabecular bone to intermittent PTH in female mice. J Bone Miner Res 20: 635-643.
    • (2005) J Bone Miner Res , vol.20 , pp. 635-643
    • Bouxsein, M.L.1    Pierroz, D.D.2    Glatt, V.3    Goddard, D.S.4    Cavat, F.5
  • 24
    • 15444367508 scopus 로고    scopus 로고
    • Bone response to intermittent parathyroid hormone is altered in mice null for {beta}- Arrestin 2
    • Ferrari SL, Pierroz DD, Glatt V, Goddard DS, Bianchi EN, et al. (2005) Bone response to intermittent parathyroid hormone is altered in mice null for {beta}- Arrestin 2. Endocrinology 146: 1854-1862.
    • (2005) Endocrinology , vol.146 , pp. 1854-1862
    • Ferrari, S.L.1    Pierroz, D.D.2    Glatt, V.3    Goddard, D.S.4    Bianchi, E.N.5
  • 25
    • 0033047422 scopus 로고    scopus 로고
    • Direct three- dimensional morphometric analysis of human cancellous bone: Microstructural data from spine, femur, iliac crest, and calcaneus
    • Hildebrand T, Laib A, Muller R, Dequeker J, Ruegsegger P (1999) Direct three- dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus. J Bone Miner Res 14: 1167-1174.
    • (1999) J Bone Miner Res , vol.14 , pp. 1167-1174
    • Hildebrand, T.1    Laib, A.2    Muller, R.3    Dequeker, J.4    Ruegsegger, P.5
  • 26
    • 0033040237 scopus 로고    scopus 로고
    • Regional distribution of Y-receptor subtype mRNAs in rat brain
    • Parker RM, Herzog H (1999) Regional distribution of Y-receptor subtype mRNAs in rat brain. Eur J Neurosci 11: 1431-1448.
    • (1999) Eur J Neurosci , vol.11 , pp. 1431-1448
    • Parker, R.M.1    Herzog, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.