Reciprocal regulation of bone and energy metabolism

Journal of Musculoskeletal Neuronal Interactions

Volumn 8, Issue 4, 2008, Pages 351-

  Lee, Na Kyung ^a   Karsenty, G ^a  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

Author keywords

Energy metabolism; Esp; Leptin; Osteoblasts; Osteocalcin

Indexed keywords

ADIPONECTIN; CELL PROTEIN; INSULIN; LEPTIN; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN ESP; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

B LYMPHOCYTE; BONE MASS; BONE REMODELING; CONFERENCE PAPER; ENERGY METABOLISM; GENE ACTIVITY; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; NONHUMAN; OSTEOBLAST; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PROCESSING; REGULATORY MECHANISM;

ANIMALS; BONE REMODELING; ENERGY METABOLISM; HUMANS; SIGNAL TRANSDUCTION;

EID: 63249120332     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (5)

1. Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 2000;100:197-207.
2. Karsenty G. Convergence between bone and energy homeostases: leptin regulation of bone mass. Cell Metab 2006;4:341-8.
3. Ducy P, Desbois C, Boyce B, Pinero G, Story B, Dunstan C, Smith E, Bonadio J, Goldstein S, Gundberg C, Bradley A, Karsenty G. Increased bone formation in osteocalcin-deficient mice. Nature 1996;382:448-52.
4. Mauro LJ, Olmsted EA, Skrobacz BM, Mourey RJ, Davis AR, Dixon JE. Identification of a hormonally regulated protein tyrosine phosphatase associated with bone and testicular differentiation. J Biol Chem 1994; 269:30659-67.
5. Lee N, Sowa H, Hinoi E, Ferron M, Ahn J, Dacquin R, Mee PJ, Mauvais-Jarvis F, Ducy P, Karsenty G. Endocrine regulation of energy metabolism by the skeleton. Cell 2007;130:456-69.