-
1
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner, S. B. Novel proteinaceous infectious particles cause scrapie. Science 216, 136-144 (1982).
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
3
-
-
0014190760
-
Self-replication and scrapie
-
Griffith, J. S. Self-replication and scrapie. Nature 21 5, 1043-1044 (1967).
-
(1967)
Nature
, vol.21
, Issue.5
, pp. 1043-1044
-
-
Griffith, J.S.1
-
4
-
-
34447530804
-
Prions of fungi: Inherited structures and biological roles
-
Wickner, R. B., Edskes, H. K., Shewmaker, F. & Nakayashiki, T. Prions of fungi: inherited structures and biological roles. Nature Rev. Microbiol. 5, 611-618 (2007).
-
(2007)
Nature Rev. Microbiol.
, vol.5
, pp. 611-618
-
-
Wickner, R.B.1
Edskes, H.K.2
Shewmaker, F.3
Nakayashiki, T.4
-
5
-
-
36049020231
-
A general model of prion strains and their pathogenicity
-
Collinge, J. & Clarke, A. R. A general model of prion strains and their pathogenicity. Science 318, 930-936 (2007).
-
(2007)
Science
, vol.318
, pp. 930-936
-
-
Collinge, J.1
Clarke, A.R.2
-
6
-
-
60549101873
-
A prion of yeast metacaspase homolog (Mca1p) detected by a genetic screen
-
Nemecek, J., Nakayashiki, T. & Wickner, R. B. A prion of yeast metacaspase homolog (Mca1p) detected by a genetic screen. Proc. Natl Acad. Sci. USA 106, 1892-1896 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 1892-1896
-
-
Nemecek, J.1
Nakayashiki, T.2
Wickner, R.B.3
-
7
-
-
0028308104
-
[URE3] as an altered URE2 protein: Evidence for a prion analog in Saccharomyces cerevisiae
-
Wickner, R. B. [URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae. Science 264, 566-569 (1994).
-
(1994)
Science
, vol.264
, pp. 566-569
-
-
Wickner, R.B.1
-
8
-
-
0034710897
-
A census of glutamine/asparagine-rich regions: Implications for their conserved function and the prediction of novel prions
-
Michelitsch, M. D. & Weissman, J. S. A census of glutamine/ asparagine-rich regions: implications for their conserved function and the prediction of novel prions. Proc. Natl Acad. Sci. USA 97, 11910-11915 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 11910-11915
-
-
Michelitsch, M.D.1
Weissman, J.S.2
-
9
-
-
63049091236
-
A systematic survey identifies prions and illuminates sequence features of prionogenic proteins
-
Alberti, S., Halfmann, R., King, O., Kapila, A. & Lindquist, S. A systematic survey identifies prions and illuminates sequence features of prionogenic proteins. Cell 137, 146-158 (2009).
-
(2009)
Cell
, vol.137
, pp. 146-158
-
-
Alberti, S.1
Halfmann, R.2
King, O.3
Kapila, A.4
Lindquist, S.5
-
10
-
-
84966138908
-
Ψ A cytoplasmic suppressor of super-suppression in yeast
-
Cox, B. Ψ, A cytoplasmic suppressor of super-suppression in yeast. Heredity 20, 505-521 (1965).
-
(1965)
Heredity
, vol.20
, pp. 505-521
-
-
Cox, B.1
-
11
-
-
0017624644
-
Frameshifts and frameshift suppressors in Saccharomyces cerevisiae
-
Culbertson, M. R., Charnas, L., Johnson, M. T. & Fink, G. R. Frameshifts and frameshift suppressors in Saccharomyces cerevisiae. Genetics 86, 745-764 (1977).
-
(1977)
Genetics
, vol.86
, pp. 745-764
-
-
Culbertson, M.R.1
Charnas, L.2
Johnson, M.T.3
Fink, G.R.4
-
12
-
-
0029780647
-
Support for the prion hypothesis for inheritance of a phenotypic trait in yeast
-
Patino, M. M., Liu, J. J., Glover, J. R. & Lindquist, S. Support for the prion hypothesis for inheritance of a phenotypic trait in yeast. Science 273, 622-626 (1996).
-
(1996)
Science
, vol.273
, pp. 622-626
-
-
Patino, M.M.1
Liu, J.J.2
Glover, J.R.3
Lindquist, S.4
-
14
-
-
33847307713
-
Prion species barrier between the closely related yeast proteins is detected despite coaggregation
-
Chen, B., Newnam, G. P. & Chernoff, Y. O. Prion species barrier between the closely related yeast proteins is detected despite coaggregation. Proc. Natl Acad. Sci. USA 104, 2791-2796 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 2791-2796
-
-
Chen, B.1
Newnam, G.P.2
Chernoff, Y.O.3
-
15
-
-
0033118934
-
Translation termination efficiency can be regulated in Saccharomyces cerevisiae by environmental stress through a prion-mediated mechanism
-
Eaglestone, S. S., Cox, B. S. & Tuite, M. F. Translation termination efficiency can be regulated in Saccharomyces cerevisiae by environmental stress through a prion-mediated mechanism. EMBO J. 18, 1974-1981 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 1974-1981
-
-
Eaglestone, S.S.1
Cox, B.S.2
Tuite, M.F.3
-
16
-
-
4544235083
-
Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits
-
True, H. L., Berlin, I. & Lindquist, S. L. Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits. Nature 431, 184-187 (2004).
-
(2004)
Nature
, vol.431
, pp. 184-187
-
-
True, H.L.1
Berlin, I.2
Lindquist, S.L.3
-
17
-
-
0034727077
-
A yeast prion provides a mechanism for genetic variation and phenotypic diversity
-
True, H. L. & Lindquist, S. L. A yeast prion provides a mechanism for genetic variation and phenotypic diversity. Nature 407, 477-483 (2000).
-
(2000)
Nature
, vol.407
, pp. 477-483
-
-
True, H.L.1
Lindquist, S.L.2
-
18
-
-
13544262685
-
Genome-wide prediction of stop codon readthrough during translation in the yeast Saccharomyces cerevisiae
-
Williams, I., Richardson, J., Starkey, A. & Stansfield, I. Genome-wide prediction of stop codon readthrough during translation in the yeast Saccharomyces cerevisiae. Nucleic Acids Res. 32, 6605-6616 (2004).
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 6605-6616
-
-
Williams, I.1
Richardson, J.2
Starkey, A.3
Stansfield, I.4
-
20
-
-
11244337377
-
Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme
-
Palanimurugan, R., Scheel, H., Hofmann, K. & Dohmen, R. J. Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme. EMBO J. 23, 4857-4867 (2004).
-
(2004)
EMBO J.
, vol.23
, pp. 4857-4867
-
-
Palanimurugan, R.1
Scheel, H.2
Hofmann, K.3
Dohmen, R.J.4
-
22
-
-
0036267441
-
Translational readthrough of the PDE2 stop codon modulates cAMP levels in Saccharomyces cerevisiae
-
Namy, O., Duchateau-Nguyen, G. & Rousset, J. P. Translational readthrough of the PDE2 stop codon modulates cAMP levels in Saccharomyces cerevisiae. Mol. Microbiol. 43, 641-652 (2002).
-
(2002)
Mol. Microbiol.
, vol.43
, pp. 641-652
-
-
Namy, O.1
Duchateau-Nguyen, G.2
Rousset, J.P.3
-
23
-
-
41349087784
-
Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae
-
Du, Z., Park, K. W., Yu, H., Fan, Q. & Li, L. Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae. Nature Genet. 40, 460-465 (2008).
-
(2008)
Nature Genet.
, vol.40
, pp. 460-465
-
-
Du, Z.1
Park, K.W.2
Yu, H.3
Fan, Q.4
Li, L.5
-
24
-
-
61849091420
-
The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion
-
Patel, B. K., Gavin-Smyth, J. & Liebman, S. W. The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion. Nature Cell Biol. 11, 344-349 (2009).
-
(2009)
Nature Cell Biol.
, vol.11
, pp. 344-349
-
-
Patel, B.K.1
Gavin-Smyth, J.2
Liebman, S.W.3
-
25
-
-
0036683476
-
Mot3 is a transcriptional repressor of ergosterol biosynthetic genes and is required for normal vacuolar function in Saccharomyces cerevisiae
-
Hongay, C., Jia, N., Bard, M. & Winston, F. Mot3 is a transcriptional repressor of ergosterol biosynthetic genes and is required for normal vacuolar function in Saccharomyces cerevisiae. EMBO J. 21, 4114-4124 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 4114-4124
-
-
Hongay, C.1
Jia, N.2
Bard, M.3
Winston, F.4
-
26
-
-
70549086622
-
Growth control and ribosome biogenesis
-
Lempiäinen, H. & Shore, D. Growth control and ribosome biogenesis. Curr. opin. Cell Biol. 21, 855-863 (2009).
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 855-863
-
-
Lempiäinen, H.1
Shore, D.2
-
27
-
-
0023954446
-
Regulation of nitrogen assimilation in Saccharomyces cerevisiae: Roles of the URE2 and GLN3 genes
-
Courchesne, W. E. & Magasanik, B. Regulation of nitrogen assimilation in Saccharomyces cerevisiae: roles of the URE2 and GLN3 genes. J. Bacteriol. 170, 708-713 (1988).
-
(1988)
J. Bacteriol.
, vol.170
, pp. 708-713
-
-
Courchesne, W.E.1
Magasanik, B.2
-
28
-
-
0034640545
-
Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gat1p and Ure2p production in Saccharomyces cerevisiae
-
Cunningham, T. S., Andhare, R. & Cooper, T. G. Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gat1p and Ure2p production in Saccharomyces cerevisiae. J. Biol. Chem. 275, 14408-14414 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14408-14414
-
-
Cunningham, T.S.1
Andhare, R.2
Cooper, T.G.3
-
29
-
-
0038305974
-
Ure2. A prion precursor with homology to glutathione S-transferase. Protects Saccharomyces cerevisiae cells from heavy metal ion and oxidant toxicity
-
Rai, R., Tate, J. J. & Cooper, T. G. Ure2, A prion precursor with homology to glutathione S-transferase, Protects Saccharomyces cerevisiae cells from heavy metal ion and oxidant toxicity. J. Biol. Chem. 278, 12826-12833 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12826-12833
-
-
Rai, R.1
Tate, J.J.2
Cooper, T.G.3
-
30
-
-
77953767980
-
+] in yeast is a nuclear-residing prion form of the global transcriptional regulator Sfp1
-
+] in yeast is a nuclear-residing prion form of the global transcriptional regulator Sfp1. Proc. Natl Acad. Sci. USA 107, 10573-10577 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10573-10577
-
-
Rogoza, T.1
-
31
-
-
62349126367
-
A short history of small s: A prion of the fungus Podospora anserina
-
Saupe, S. J. A short history of small s: a prion of the fungus Podospora anserina. Prion 1, 110-115 (2007).
-
(2007)
Prion
, vol.1
, pp. 110-115
-
-
Saupe, S.J.1
-
32
-
-
0030885650
-
The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog
-
Coustou, V., Deleu, C., Saupe, S. & Begueret, J. The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog. Proc. Natl Acad. Sci. USA 94, 9773-9778 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 9773-9778
-
-
Coustou, V.1
Deleu, C.2
Saupe, S.3
Begueret, J.4
-
33
-
-
70549098240
-
Fungal incompatibility: Evolutionary origin in pathogen defense?
-
Paoletti, M. & Saupe, S. J. Fungal incompatibility: evolutionary origin in pathogen defense? Bioessays 31, 1201-1210 (2009).
-
(2009)
Bioessays
, vol.31
, pp. 1201-1210
-
-
Paoletti, M.1
Saupe, S.J.2
-
34
-
-
77955504368
-
The mechanism of prion inhibition by HET-S
-
Greenwald, J. et al. The mechanism of prion inhibition by HET-S. Mol. Cell 38, 889-899 (2010).
-
(2010)
Mol. Cell
, vol.38
, pp. 889-899
-
-
Greenwald, J.1
-
35
-
-
0033969457
-
Rnq1: An epigenetic modifier of protein function in yeast
-
Sondheimer, N. & Lindquist, S. Rnq1: an epigenetic modifier of protein function in yeast. Mol. Cell 5, 163-172 (2000).
-
(2000)
Mol. Cell
, vol.5
, pp. 163-172
-
-
Sondheimer, N.1
Lindquist, S.2
-
38
-
-
0041563922
-
Prion protein gene polymorphisms in Saccharomyces cerevisiae
-
Resende, C. G., Outeiro, T. F., Sands, L., Lindquist, S. & Tuite, M. F. Prion protein gene polymorphisms in Saccharomyces cerevisiae. Mol. Microbiol. 49, 1005-1017 (2003).
-
(2003)
Mol. Microbiol.
, vol.49
, pp. 1005-1017
-
-
Resende, C.G.1
Outeiro, T.F.2
Sands, L.3
Lindquist, S.4
Tuite, M.F.5
-
40
-
-
4444312783
-
+] prion in yeast and aggregation of Sup35 in vitro
-
+] prion in yeast and aggregation of Sup35 in vitro. Proc. Natl Acad. Sci. USA 101, 12934-12939 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 12934-12939
-
-
Derkatch, I.L.1
-
41
-
-
0034595216
-
+]: A two-prion system in yeast?
-
+]: a two-prion system in yeast? EMBO J. 19, 1942-1952 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 1942-1952
-
-
Derkatch, I.L.1
-
42
-
-
0037783482
-
Sexual transmission of the [Het-S] prion leads to meiotic drive in Podospora anserina
-
Dalstra, H. J., Swart, K., Debets, A. J., Saupe, S. J. & Hoekstra, R. F. Sexual transmission of the [Het-S] prion leads to meiotic drive in Podospora anserina. Proc. Natl Acad. Sci. USA 100, 6616-6621 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 6616-6621
-
-
Dalstra, H.J.1
Swart, K.2
Debets, A.J.3
Saupe, S.J.4
Hoekstra, R.F.5
-
43
-
-
0027513128
-
Deletion analysis of the SUP35 gene of the yeast Saccharomyces cerevisiae reveals two non-overlapping functional regions in the encoded protein
-
Ter-Avanesyan, M. D. et al. Deletion analysis of the SUP35 gene of the yeast Saccharomyces cerevisiae reveals two non-overlapping functional regions in the encoded protein. Mol. Microbiol. 7, 683-692 (1993).
-
(1993)
Mol. Microbiol.
, vol.7
, pp. 683-692
-
-
Ter-Avanesyan, M.D.1
-
44
-
-
67651230677
-
Complex adaptations can drive the evolution of the capacitor [PSI] even with realistic rates of yeast sex
-
Griswold, C. K. & Masel, J. Complex adaptations can drive the evolution of the capacitor [PSI], Even with realistic rates of yeast sex. PLoS Genet. 5, E1000517 (2009).
-
(2009)
PLoS Genet.
, vol.5
-
-
Griswold, C.K.1
Masel, J.2
-
46
-
-
77949848854
-
Prion-like transmission of protein aggregates in neurodegenerative diseases
-
Brundin, P., Melki, R. & Kopito, R. Prion-like transmission of protein aggregates in neurodegenerative diseases. Nature Rev. Mol. Cell Biol. 11, 301-307 (2010).
-
(2010)
Nature Rev. Mol. Cell Biol.
, vol.11
, pp. 301-307
-
-
Brundin, P.1
Melki, R.2
Kopito, R.3
-
47
-
-
33749020837
-
Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host
-
Meyer-Luehmann, M. et al. Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host. Science 313, 1781-1784 (2006).
-
(2006)
Science
, vol.313
, pp. 1781-1784
-
-
Meyer-Luehmann, M.1
-
48
-
-
59649095699
-
Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates
-
Ren, P. H. et al. Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates. Nature Cell Biol. 11, 219-225 (2009).
-
(2009)
Nature Cell Biol.
, vol.11
, pp. 219-225
-
-
Ren, P.H.1
-
49
-
-
43249110200
-
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
-
Li, J. Y. et al. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation. Nature Med. 14, 501-503 (2008).
-
(2008)
Nature Med.
, vol.14
, pp. 501-503
-
-
Li, J.Y.1
-
50
-
-
67649286622
-
Cell biology: Beyond the prion principle
-
Aguzzi, A. Cell biology: Beyond the prion principle. Nature 459, 924-925 (2009).
-
(2009)
Nature
, vol.459
, pp. 924-925
-
-
Aguzzi, A.1
-
51
-
-
33344463679
-
Common mechanisms of amyloid oligomer pathogenesis in degenerative disease
-
Glabe, C. G. Common mechanisms of amyloid oligomer pathogenesis in degenerative disease. Neurobiol. Aging 27, 570-575 (2006).
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 570-575
-
-
Glabe, C.G.1
-
53
-
-
75749134925
-
Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation
-
Si, K., Choi, Y. B., White-Grindley, E., Majumdar, A. & Kandel, E. R. Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation. Cell 140, 421-435 (2010).
-
(2010)
Cell
, vol.140
, pp. 421-435
-
-
Si, K.1
Choi, Y.B.2
White-Grindley, E.3
Majumdar, A.4
Kandel, E.R.5
-
54
-
-
31144460030
-
Functional amyloid formation within mammalian tissue
-
Fowler, D. M. et al. Functional amyloid formation within mammalian tissue. PLoS Biol. 4, E6 (2006).
-
(2006)
PLoS Biol.
, vol.4
-
-
Fowler, D.M.1
-
55
-
-
0037986392
-
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis
-
Berson, J. F. et al. Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis. J. Cell Biol. 161, 521-533 (2003).
-
(2003)
J. Cell Biol.
, vol.161
, pp. 521-533
-
-
Berson, J.F.1
-
56
-
-
67650809307
-
Functional amyloids as natural storage of peptide hormones in pituitary secretory granules
-
Maji, S. K. et al. Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science 325, 328-332 (2009).
-
(2009)
Science
, vol.325
, pp. 328-332
-
-
Maji, S.K.1
-
57
-
-
48249126806
-
The prion's elusive reason for being
-
Aguzzi, A., Baumann, F. & Bremer, J. The prion's elusive reason for being. Annu. Rev. Neurosci. 31, 439-477 (2008).
-
(2008)
Annu. Rev. Neurosci.
, vol.31
, pp. 439-477
-
-
Aguzzi, A.1
Baumann, F.2
Bremer, J.3
-
58
-
-
33846538022
-
Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice
-
Mallucci, G. R. et al. Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice. Neuron 53, 325-335 (2007).
-
(2007)
Neuron
, vol.53
, pp. 325-335
-
-
Mallucci, G.R.1
-
59
-
-
48249108696
-
Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease
-
White, M. D. et al. Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease. Proc. Natl Acad. Sci. USA 105, 10238-10243 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 10238-10243
-
-
White, M.D.1
-
60
-
-
43149121009
-
The prion protein knockout mouse: A phenotype under challenge
-
Steele, A. D., Lindquist, S. & Aguzzi, A. The prion protein knockout mouse: a phenotype under challenge. Prion 1, 83-93 (2007).
-
(2007)
Prion
, vol.1
, pp. 83-93
-
-
Steele, A.D.1
Lindquist, S.2
Aguzzi, A.3
-
61
-
-
33748713915
-
The role of the cellular prion protein in the immune system
-
Isaacs, J. D., Jackson, G. S. & Altmann, D. M. The role of the cellular prion protein in the immune system. Clin. Exp. Immunol. 146, 1-8 (2006).
-
(2006)
Clin. Exp. Immunol.
, vol.146
, pp. 1-8
-
-
Isaacs, J.D.1
Jackson, G.S.2
Altmann, D.M.3
-
62
-
-
58149109172
-
Sniffing out a function for prion proteins
-
Wilson, D. A. & Nixon, R. A. Sniffing out a function for prion proteins. Nature Neurosci. 12, 7-8 (2009).
-
(2009)
Nature Neurosci.
, vol.12
, pp. 7-8
-
-
Wilson, D.A.1
Nixon, R.A.2
-
63
-
-
65949115708
-
Regulation of embryonic cell adhesion by the prion protein
-
Malaga-Trillo, E. et al. Regulation of embryonic cell adhesion by the prion protein. PLoS Biol. 7, E55 (2009).
-
(2009)
PLoS Biol.
, vol.7
-
-
Malaga-Trillo, E.1
-
64
-
-
77649091387
-
Axonal prion protein is required for peripheral myelin maintenance
-
Bremer, J. et al. Axonal prion protein is required for peripheral myelin maintenance. Nature Neurosci. 13, 310-318 (2010).
-
(2010)
Nature Neurosci.
, vol.13
, pp. 310-318
-
-
Bremer, J.1
-
66
-
-
0001552281
-
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
-
Shmerling, D. et al. Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell 93, 203-214 (1998).
-
(1998)
Cell
, vol.93
, pp. 203-214
-
-
Shmerling, D.1
-
67
-
-
33846498655
-
Lethal recessive myelin toxicity of prion protein lacking its central domain
-
Baumann, F. et al. Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J. 26, 538-547 (2007).
-
(2007)
EMBO J.
, vol.26
, pp. 538-547
-
-
Baumann, F.1
-
68
-
-
0242363656
-
Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
-
Mallucci, G. et al. Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science 302, 871-874 (2003).
-
(2003)
Science
, vol.302
, pp. 871-874
-
-
Mallucci, G.1
-
69
-
-
0030054010
-
Normal host prion protein necessary for scrapie-induced neurotoxicity
-
Brandner, S. et al. Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature 379, 339-343 (1996).
-
(1996)
Nature
, vol.379
, pp. 339-343
-
-
Brandner, S.1
-
70
-
-
20344394154
-
Anchorless prion protein results in infectious amyloid disease without clinical scrapie
-
Chesebro, B. et al. Anchorless prion protein results in infectious amyloid disease without clinical scrapie. Science 308, 1435-1439 (2005).
-
(2005)
Science
, vol.308
, pp. 1435-1439
-
-
Chesebro, B.1
-
71
-
-
67649803600
-
Preventing prion pathogenicity by targeting the cellular prion protein
-
Nicoll, A. J. & Collinge, J. Preventing prion pathogenicity by targeting the cellular prion protein. Infect. Disord. Drug Targets 9, 48-57 (2009).
-
(2009)
Infect. Disord. Drug Targets
, vol.9
, pp. 48-57
-
-
Nicoll, A.J.1
Collinge, J.2
-
72
-
-
74749108295
-
C in mediating the neurotoxic effect of scrapie prions in neurons
-
C in mediating the neurotoxic effect of scrapie prions in neurons. Curr. Issues Mol. Biol. 12, 119-128 (2009).
-
(2009)
Curr. Issues Mol. Biol.
, vol.12
, pp. 119-128
-
-
Radford, H.E.1
Mallucci, G.R.2
-
73
-
-
0028535880
-
Sc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene
-
Sc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Mol. Med. 1, 19-30 (1994).
-
(1994)
Mol. Med.
, vol.1
, pp. 19-30
-
-
Büeler, H.1
-
74
-
-
0032968132
-
Quantifying the kinetic parameters of prion replication
-
Masel, J., Jansen, V. A. & Nowak, M. A. Quantifying the kinetic parameters of prion replication. Biophys. Chem. 77, 139-152 (1999).
-
(1999)
Biophys. Chem.
, vol.77
, pp. 139-152
-
-
Masel, J.1
Jansen, V.A.2
Nowak, M.A.3
-
75
-
-
75349113019
-
Towards a unifying mechanism for ClpB/Hsp104-mediated protein disaggregation and prion propagation
-
Haslberger, T., Bukau, B. & Mogk, A. Towards a unifying mechanism for ClpB/Hsp104-mediated protein disaggregation and prion propagation. Biochem. Cell Biol. 88, 63-75 (2010).
-
(2010)
Biochem. Cell Biol.
, vol.88
, pp. 63-75
-
-
Haslberger, T.1
Bukau, B.2
Mogk, A.3
-
76
-
-
24644439320
-
Chaperoning prions: The cellular machinery for propagating an infectious protein?
-
Jones, G. W. & Tuite, M. F. Chaperoning prions: the cellular machinery for propagating an infectious protein? Bioessays 27, 823-832 (2005).
-
(2005)
Bioessays
, vol.27
, pp. 823-832
-
-
Jones, G.W.1
Tuite, M.F.2
-
77
-
-
0025244011
-
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
-
Prusiner, S. et al. Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell 63, 673-686 (1990).
-
(1990)
Cell
, vol.63
, pp. 673-686
-
-
Prusiner, S.1
-
78
-
-
0028703452
-
PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology
-
Manson, J. C., Clarke, A. R., McBride, P. A., McConnell, I. & Hope, J. PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology. Neurodegeneration 3, 331-340 (1994).
-
(1994)
Neurodegeneration
, vol.3
, pp. 331-340
-
-
Manson, J.C.1
Clarke, A.R.2
McBride, P.A.3
McConnell, I.4
Hope, J.5
-
79
-
-
0032485810
-
Bistability and the species barrier in prion diseases: Stepping across the threshold or not
-
Laurent, M. Bistability and the species barrier in prion diseases: stepping across the threshold or not. Biophys. Chem. 72, 211-222 (1998).
-
(1998)
Biophys. Chem.
, vol.72
, pp. 211-222
-
-
Laurent, M.1
-
80
-
-
71549160322
-
Prion dynamics and the quest for the genetic determinant in protein-only inheritance
-
Sindi, S. S. & Serio, T. R. Prion dynamics and the quest for the genetic determinant in protein-only inheritance. Curr. opin. Microbiol. 12, 623-630 (2009).
-
(2009)
Curr. Opin. Microbiol.
, vol.12
, pp. 623-630
-
-
Sindi, S.S.1
Serio, T.R.2
-
81
-
-
34447639732
-
Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes
-
Legname, G. et al. Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes. Proc. Natl Acad. Sci. USA 103, 19105-19110 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 19105-19110
-
-
Legname, G.1
-
82
-
-
33746698975
-
The physical basis of how prion conformations determine strain phenotypes
-
Tanaka, M., Collins, S. R., Toyama, B. H. & Weissman, J. S. The physical basis of how prion conformations determine strain phenotypes. Nature 442, 585-589 (2006).
-
(2006)
Nature
, vol.442
, pp. 585-589
-
-
Tanaka, M.1
Collins, S.R.2
Toyama, B.H.3
Weissman, J.S.4
-
83
-
-
0017866857
-
Evidence that the transmission of one source of scrapie agent to hamsters involves separation of agent strains from a mixture
-
Kimberlin, R. H. & Walker, C. A. Evidence that the transmission of one source of scrapie agent to hamsters involves separation of agent strains from a mixture. J. Gen. Virol. 39, 487-496 (1978).
-
(1978)
J. Gen. Virol.
, vol.39
, pp. 487-496
-
-
Kimberlin, R.H.1
Walker, C.A.2
-
84
-
-
0001273462
-
-
(eds Prusiner, S. B. & Hadlow, W. J.) Academy Press, New York
-
Marsh, R. F. & Hanson, R. P. in Slow Transmissible Diseases of the Nervous System (eds Prusiner, S. B. & Hadlow, W. J.) 451-460 (Academy Press, New York, 1979).
-
(1979)
P. in Slow Transmissible Diseases of the Nervous System
, pp. 451-460
-
-
Marsh, R.F.1
Hanson, R.2
-
85
-
-
0242558824
-
-
(ed. Kimberlin, R. H.) North-Holland Publishing Company, Amsterdam
-
Dickinson, A. G. in Slow Virus Diseases of Animals and Man (ed. Kimberlin, R. H.) 209-241 (North-Holland Publishing Company, Amsterdam, 1976).
-
(1976)
G. in Slow Virus Diseases of Animals and Man
, pp. 209-241
-
-
Dickinson, A.1
-
87
-
-
72649091794
-
Continuous quinacrine treatment results in the formation of drug-resistant prions
-
Ghaemmaghami, S. et al. Continuous quinacrine treatment results in the formation of drug-resistant prions. PLoS Pathog. 5, E1000673 (2009). Quinacrine treatment induces the loss of some prion strains while promoting the amplification of others.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Ghaemmaghami, S.1
-
88
-
-
0030758270
-
Evolution of a strain of CJD that induces BSE-like plaques
-
Manuelidis, L., Fritch, W. & Xi, Y. G. Evolution of a strain of CJD that induces BSE-like plaques. Science 277, 94-98 (1997).
-
(1997)
Science
, vol.277
, pp. 94-98
-
-
Manuelidis, L.1
Fritch, W.2
Xi, Y.G.3
-
89
-
-
76749109480
-
Darwinian evolution of prions in cell culture
-
Li, J., Browning, S., Mahal, S. P., Oelschlegel, A. M. & Weissmann, C. Darwinian evolution of prions in cell culture. Science 327, 869-872 (2010).
-
Science
, vol.327
, Issue.869-872
, pp. 2010
-
-
Li, J.1
Browning, S.2
Mahal, S.P.3
Oelschlegel, A.M.4
Weissmann, C.5
-
90
-
-
0027740178
-
Scrapie strain variation and mutation
-
Bruce, M. E. Scrapie strain variation and mutation. Br. Med. Bull. 49, 822-838 (1993).
-
(1993)
Br. Med. Bull.
, vol.49
, pp. 822-838
-
-
Bruce, M.E.1
-
91
-
-
77952964383
-
Prion strain mutation determined by prion protein conformational compatibility and primary structure
-
Angers, R. C. et al. Prion strain mutation determined by prion protein conformational compatibility and primary structure. Science 328, 1154-1158 (2010).
-
(2010)
Science
, vol.328
, pp. 1154-1158
-
-
Angers, R.C.1
-
92
-
-
0026558780
-
Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters
-
Bessen, R. A. & Marsh, R. F. Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters. J. Gen. Virol. 73, 329-334 (1992).
-
(1992)
J. Gen. Virol.
, vol.73
, pp. 329-334
-
-
Bessen, R.A.1
Marsh, R.F.2
-
93
-
-
2442521869
-
-
(eds Court, L. A. & Cathala, F. ) (Masson, Paris
-
Dickinson, A. G. & Outram, G. W. in Virus Nonconventionnels et Affections du Systeme Nerveux Central (eds Court, L. A. & Cathala, F. ) 3-16 (Masson, Paris, 1983).
-
(1983)
W. in Virus Nonconventionnels et Affections du Systeme Nerveux Central
, pp. 3-16
-
-
Dickinson, A.G.1
Outram, G.2
-
94
-
-
70449524296
-
Sc types: An updated classification
-
Sc types: an updated classification. Acta Neuropathol. 1 1 8, 659-671 (2009).
-
(2009)
Acta Neuropathol.
, vol.1
, Issue.18
, pp. 659-671
-
-
Parchi, P.1
-
95
-
-
70349937836
-
Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: Its effect on the phenotype and prion-type characteristics
-
Cali, I. et al. Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristics. Brain 132, 2643-2658 (2009).
-
(2009)
Brain
, vol.132
, pp. 2643-2658
-
-
Cali, I.1
-
96
-
-
0003467727
-
-
(eds Prusiner S. Collinge J. Powell J. & Anderton B.) (Ellis Horwood, New York
-
Bruce, M., Fraser, H., McBride, P., Scott, J. & Dickinson, A. in Prion Diseases of Humans and Animals (eds Prusiner, S., Collinge, J., Powell, J. & Anderton, B.) 497-508 (Ellis Horwood, New York, 1992).
-
(1992)
Prion Diseases of Humans and Animals
, pp. 497-508
-
-
Bruce, M.1
Fraser, H.2
McBride, P.3
Scott, J.4
Dickinson, A.5
-
97
-
-
0034079165
-
Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy
-
Bartz, J. C., Bessen, R. A., McKenzie, D., Marsh, R. F. & Aiken, J. M. Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy. J. Virol. 74, 5542-5547 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 5542-5547
-
-
Bartz, J.C.1
Bessen, R.A.2
McKenzie, D.3
Marsh, R.F.4
Aiken, J.M.5
-
98
-
-
0016431525
-
Extraneural competition between different scrapie agents leading to loss of infectivity
-
Dickinson, A. G. et al. Extraneural competition between different scrapie agents leading to loss of infectivity. Nature 253, 556 (1975).
-
(1975)
Nature
, vol.253
, pp. 556
-
-
Dickinson, A.G.1
-
99
-
-
0015518449
-
Competition between different scrapie agents in mice
-
Dickinson, A. G., Fraser, H., Meikle, V. M. & Outram, G. W. Competition between different scrapie agents in mice. Nature New Biol. 237, 244-245 (1972).
-
(1972)
Nature New Biol.
, vol.237
, pp. 244-245
-
-
Dickinson, A.G.1
Fraser, H.2
Meikle, V.M.3
Outram, G.W.4
-
100
-
-
0003816270
-
-
(eds Prusiner, S. B. & Hadlow, W. J.) Academic Press, New York
-
Dickinson, A. G. & Outram, G. W. in Slow Transmissible Diseases of The Nervous System (eds Prusiner, S. B. & Hadlow, W. J.) 13-31 (Academic Press, New York, 1979).
-
(1979)
W. in Slow Transmissible Diseases of the Nervous System
, pp. 13-31
-
-
Dickinson, A.G.1
Outram, G.2
-
101
-
-
77951996350
-
Coinfecting prion strains compete for a limiting cellular resource
-
Shikiya, R. A., Ayers, J. I., Schutt, C. R., Kincaid, A. E. & Bartz, J. C. Coinfecting prion strains compete for a limiting cellular resource. J. Virol. 84, 5706-5714 (2010).
-
(2010)
J. Virol.
, vol.84
, pp. 5706-5714
-
-
Shikiya, R.A.1
Ayers, J.I.2
Schutt, C.R.3
Kincaid, A.E.4
Bartz, J.C.5
-
102
-
-
0037058953
-
Interactions among prions and prion "strains" in yeast
-
Bradley, M. E., Edskes, H. K., Hong, J. Y., Wickner, R. B. & Liebman, S. W. Interactions among prions and prion "strains" in yeast. Proc. Natl Acad. Sci. USA 99 (Suppl. 4), 16392-16399 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, Issue.SUPPL. 4
, pp. 16392-16399
-
-
Bradley, M.E.1
Edskes, H.K.2
Hong, J.Y.3
Wickner, R.B.4
Liebman, S.W.5
-
103
-
-
34249993165
-
The prion strain phenomenon: Molecular basis and unprecedented features
-
Morales, R., Abid, K. & Soto, C. The prion strain phenomenon: molecular basis and unprecedented features. Biochim. Biophys. Acta 1772, 681-691 (2007).
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, pp. 681-691
-
-
Morales, R.1
Abid, K.2
Soto, C.3
-
104
-
-
0000757134
-
Patients wth Creutzfeldt-Jakob disease and kuru lack the mutation in the PRIP gene found in Gerstmann-Sträussler syndrome but they show a different double-allele mutation in the same gene
-
Goldfarb, L. et al. Patients wth Creutzfeldt-Jakob disease and kuru lack the mutation in the PRIP gene found in Gerstmann-Sträussler syndrome, But they show a different double-allele mutation in the same gene. Am. J. Hum. Genet. 45, A189 (1989).
-
(1989)
Am. J. Hum. Genet.
, vol.45
-
-
Goldfarb, L.1
-
105
-
-
0025287947
-
Codon 129 changes in the prion protein gene in Caucasians
-
Owen, F., Poulter, M., Collinge, J. & Crow, T. J. Codon 129 changes in the prion protein gene in Caucasians. Am. J. Hum. Genet. 46, 1215-1216 (1990).
-
(1990)
Am. J. Hum. Genet.
, vol.46
, pp. 1215-1216
-
-
Owen, F.1
Poulter, M.2
Collinge, J.3
Crow, T.J.4
-
106
-
-
0033574161
-
Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein
-
Liemann, S. & Glockshuber, R. Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein. Biochemistry 38, 3258-3267 (1999).
-
(1999)
Biochemistry
, vol.38
, pp. 3258-3267
-
-
Liemann, S.1
Glockshuber, R.2
-
108
-
-
28544443624
-
Polymorphism at residue 129 modulates the conformational conversion of the D178N variant of human prion protein 90-231
-
Apetri, A. C., Vanik, D. L. & Surewicz, W. K. Polymorphism at residue 129 modulates the conformational conversion of the D178N variant of human prion protein 90-231. Biochemistry 44, 15880-15888 (2005).
-
(2005)
Biochemistry
, vol.44
, pp. 15880-15888
-
-
Apetri, A.C.1
Vanik, D.L.2
Surewicz, W.K.3
-
109
-
-
0037077234
-
Pathway complexity of prion protein assembly into amyloid
-
Baskakov, I. V., Legname, G., Baldwin, M. A., Prusiner, S. B. & Cohen, F. E. Pathway complexity of prion protein assembly into amyloid. J. Biol. Chem. 277, 21140-21148 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21140-21148
-
-
Baskakov, I.V.1
Legname, G.2
Baldwin, M.A.3
Prusiner, S.B.4
Cohen, F.E.5
-
110
-
-
0027975260
-
Predisposition of prion protein homozygotes to Creutzfeldt-Jakob disease can be explained by a nucleation-dependent polymerization mechanism
-
Come, J. & Lansbury, P. Predisposition of prion protein homozygotes to Creutzfeldt-Jakob disease can be explained by a nucleation-dependent polymerization mechanism. J. Am. Chem. Soc. 1 1 6, 410 9-4110 (1994).
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 4109-4110
-
-
Come, J.1
Lansbury, P.2
-
111
-
-
3843131903
-
Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant: Implications for disease susceptibility to Creutzfeldt-Jakob diseases
-
Tahiri-Alaoui, A., Gill, A. C., Disterer, P. & James, W. Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant: implications for disease susceptibility to Creutzfeldt-Jakob disease. J. Biol. Chem. 279, 31390-31397 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 31390-31397
-
-
Tahiri-Alaoui, A.1
Gill, A.C.2
Disterer, P.3
James, W.4
-
112
-
-
33845958366
-
Molecular heterosis of prion protein β-oligomers. A potential mechanism of human resistance to disease
-
Tahiri-Alaoui, A., Sim, V. L., Caughey, B. & James, W. Molecular heterosis of prion protein β-oligomers. A potential mechanism of human resistance to disease. J. Biol. Chem. 281, 34171-34178 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 34171-34178
-
-
Tahiri-Alaoui, A.1
Sim, V.L.2
Caughey, B.3
James, W.4
-
113
-
-
28344436044
-
Association of sporadic Creutzfeldt-Jakob disease with homozygous genotypes at PRNP codons 129 and 219 in the Korean population
-
Jeong, B. H. et al. Association of sporadic Creutzfeldt-Jakob disease with homozygous genotypes at PRNP codons 129 and 219 in the Korean population. Neurogenetics 6, 229-232 (2005).
-
(2005)
Neurogenetics
, vol.6
, pp. 229-232
-
-
Jeong, B.H.1
-
114
-
-
0023467393
-
Distinct prion proteins in short and long scrapie incubation period mice
-
Westaway, D. et al. Distinct prion proteins in short and long scrapie incubation period mice. Cell 51, 651-662 (1987).
-
(1987)
Cell
, vol.51
, pp. 651-662
-
-
Westaway, D.1
-
115
-
-
0014305661
-
Identification of a gene which controls the incubation period of some strains of scrapie agent in mice
-
Dickinson, A. G., Meikle, V. M. & Fraser, H. Identification of a gene which controls the incubation period of some strains of scrapie agent in mice. J. Comp. Pathol. 78, 293-299 (1968).
-
(1968)
J. Comp. Pathol.
, vol.78
, pp. 293-299
-
-
Dickinson, A.G.1
Meikle, V.M.2
Fraser, H.3
-
116
-
-
0024276258
-
The unusual properties of CH1641 A sheep-passaged isolate of scrapie
-
Foster, J. D. & Dickinson, A. G. The unusual properties of CH1641, A sheep-passaged isolate of scrapie. Vet. Rec. 123, 5-8 (1988).
-
(1988)
Vet. Rec.
, vol.123
, pp. 5-8
-
-
Foster, J.D.1
Dickinson, A.G.2
-
117
-
-
0028349264
-
PrP genotype and agent effects in scrapie: Change in allelic interaction with different isolates of agent in sheep A natural host of scrapie
-
Goldmann, W., Hunter, N., Smith, G., Foster, J. & Hope, J. PrP genotype and agent effects in scrapie: change in allelic interaction with different isolates of agent in sheep, A natural host of scrapie. J. Gen. Virol. 75, 989-995 (1994).
-
(1994)
J. Gen. Virol.
, vol.75
, pp. 989-995
-
-
Goldmann, W.1
Hunter, N.2
Smith, G.3
Foster, J.4
Hope, J.5
-
119
-
-
0031842845
-
Codon 219 Lys allele of PRNP is not found in sporadic Creutzfeldt-Jakob disease
-
Shibuya, S., Higuchi, J., Shin, R. W., Tateishi, J. & Kitamoto, T. Codon 219 Lys allele of PRNP is not found in sporadic Creutzfeldt-Jakob disease. Ann. Neurol. 43, 826-828 (1998).
-
(1998)
Ann. Neurol.
, vol.43
, pp. 826-828
-
-
Shibuya, S.1
Higuchi, J.2
Shin, R.W.3
Tateishi, J.4
Kitamoto, T.5
-
120
-
-
0028267507
-
Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie
-
Westaway, D. et al. Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie. Genes Dev. 8, 959-969 (1994).
-
(1994)
Genes Dev.
, vol.8
, pp. 959-969
-
-
Westaway, D.1
-
121
-
-
0030931519
-
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation
-
Kaneko, K. et al. Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation. Proc. Natl Acad. Sci. USA 94, 10069-10074 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 10069-10074
-
-
Kaneko, K.1
-
122
-
-
0036791019
-
Dominant-negative inhibition of prion replication in transgenic mice
-
Perrier, V. et al. Dominant-negative inhibition of prion replication in transgenic mice. Proc. Natl Acad. Sci. USA 99, 13079-13084 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 13079-13084
-
-
Perrier, V.1
-
123
-
-
70049109405
-
Trans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactor
-
Geoghegan, J. C,. Miller, M. B,. Kwak, A. H,. Harris, B. T. & Supattapone, S. Trans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactor. PLoS Pathog. 5, E1000535 (2009).
-
(2009)
PLoS Pathog.
, vol.5
-
-
Geoghegan, J.C.1
Miller, M.B.2
Kwak, A.H.3
Harris, B.T.4
Supattapone, S.5
-
124
-
-
34748863748
-
The dominant-negative effect of the Q218K variant of the prion protein does not require protein X
-
Lee, C. I., Yang, Q., Perrier, V. & Baskakov, I. V. The dominant-negative effect of the Q218K variant of the prion protein does not require protein X. Protein Sci. 16, 2166-2173 (2007).
-
(2007)
Protein Sci.
, vol.16
, pp. 2166-2173
-
-
Lee, C.I.1
Yang, Q.2
Perrier, V.3
Baskakov, I.V.4
-
125
-
-
0034672723
-
Designing drugs to stop the formation of prion aggregates and other amyloids
-
Masel, J. & Jansen, V. A. Designing drugs to stop the formation of prion aggregates and other amyloids. Biophys. Chem. 88, 247-259 (2000).
-
(2000)
Biophys. Chem.
, vol.88
, pp. 247-259
-
-
Masel, J.1
Jansen, V.A.2
-
126
-
-
0032568793
-
A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion
-
DePace, A. H., Santoso, A., Hillner, P. & Weissman, J. S. A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion. Cell 93, 1241-1252 (1998).
-
(1998)
Cell
, vol.93
, pp. 1241-1252
-
-
Depace, A.H.1
Santoso, A.2
Hillner, P.3
Weissman, J.S.4
-
127
-
-
84966153836
-
Extrachromosomal elements in a super-suppression system of yeast i A nuclear gene controlling the inheritance of the extrachromosomal elements
-
Young, C. & Cox, B. Extrachromosomal elements in a super-suppression system of yeast I. A nuclear gene controlling the inheritance of the extrachromosomal elements. Heredity 26, 413-422 (1971).
-
(1971)
Heredity
, vol.26
, pp. 413-422
-
-
Young, C.1
Cox, B.2
-
128
-
-
0028174948
-
- mutation which eliminates the Ψ factor of Saccharomyces cerevisiae is the result of a missense mutation in the SUP35 gene
-
- mutation which eliminates the Ψ factor of Saccharomyces cerevisiae is the result of a missense mutation in the SUP35 gene. Genetics 137, 659-670 (1994).
-
(1994)
Genetics
, vol.137
, pp. 659-670
-
-
Doel, S.M.1
McCready, S.J.2
Nierras, C.R.3
Cox, B.S.4
-
129
-
-
0035853292
-
Supporting the structural basis of prion strains: Induction and identification of [PSI] variants
-
King, C. Y. Supporting the structural basis of prion strains: induction and identification of [PSI] variants. J. Mol. Biol. 307, 1247-1260 (2001).
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 1247-1260
-
-
King, C.Y.1
-
130
-
-
0032189203
-
+prion determinant propagation by a mutation of the N-terminus of the yeast Sup35 protein
-
+prion determinant propagation by a mutation of the N-terminus of the yeast Sup35 protein. EMBO J. 17, 5805-5810 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 5805-5810
-
-
Kochneva-Pervukhova, N.V.1
-
131
-
-
19344366926
-
Dissection and design of yeast prions
-
Osherovich, L. Z., Cox, B. S., Tuite, M. F. & Weissman, J. S. Dissection and design of yeast prions. PLoS Biol. 2, E86 (2004).
-
(2004)
PLoS Biol.
, vol.2
-
-
Osherovich, L.Z.1
Cox, B.S.2
Tuite, M.F.3
Weissman, J.S.4
-
132
-
-
50549210570
-
Experimental transmission of mouse passaged scrapie to goats, Sheep, Rats and hamsters
-
Zlotnik, I. & Rennie, J. C. Experimental transmission of mouse passaged scrapie to goats, Sheep, Rats and hamsters. J. Comp. Pathol. 75, 147-157 (1965).
-
(1965)
J. Comp. Pathol.
, vol.75
, pp. 147-157
-
-
Zlotnik, I.1
Rennie, J.C.2
-
133
-
-
0001074386
-
-
(eds Gajdusek D. C., Gibbs C. J. Jr & Alpers M. P.) (US National Institutes of Health, Bethesda, Maryland
-
Pattison, I. in NINDB Monograph, No.2: Slow, Latent, And Temperate Virus Infections (eds Gajdusek D. C., Gibbs C. J. Jr & Alpers M. P.) 249-257 (US National Institutes of Health, Bethesda, Maryland, 1965).
-
(1965)
NINDB Monograph, No.2: Slow, Latent, and Temperate Virus Infections
, pp. 249-257
-
-
Pattison, I.1
-
134
-
-
0029831213
-
Molecular analysis of prion strain variation and the aetiology of 'new variant'
-
Collinge, J., Sidle, K. C., Meads, J., Ironside, J. & Hill, A. F. Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. Nature 383, 685-690 (1996).
-
(1996)
CJD. Nature
, vol.383
, pp. 685-690
-
-
Collinge, J.1
Sidle, K.C.2
Meads, J.3
Ironside, J.4
Hill, A.F.5
-
135
-
-
0030775632
-
Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent
-
Bruce, M. E. et al. Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 389, 498-501 (1997).
-
(1997)
Nature
, vol.389
, pp. 498-501
-
-
Bruce, M.E.1
-
136
-
-
0014653715
-
A preliminary report on the experimental host range of the transmissible mink encephalopathy agent
-
Marsh, R. F., Burger, D., Eckroade, R., Zu Rhein, G. M. & Hanson, R. P. A preliminary report on the experimental host range of the transmissible mink encephalopathy agent. J. Infect. Dis. 120, 713-719 (1969).
-
(1969)
J. Infect. Dis.
, vol.120
, pp. 713-719
-
-
Marsh, R.F.1
Burger, D.2
Eckroade, R.3
Zu Rhein, G.M.4
Hanson, R.P.5
-
137
-
-
0034730170
-
Species-barrier-independent prion replication in apparently resistant species
-
Hill, A. F. et al. Species-barrier-independent prion replication in apparently resistant species. Proc. Natl Acad. Sci. USA 97, 10248-10253 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 10248-10253
-
-
Hill, A.F.1
-
138
-
-
0032560124
-
Scrapie infectivity found in resistant species
-
Race, R. & Chesebro, B. Scrapie infectivity found in resistant species. Nature 392, 770 (1998).
-
(1998)
Nature
, vol.392
, pp. 770
-
-
Race, R.1
Chesebro, B.2
-
139
-
-
0016702129
-
Scrapie incubation time can exceed natural lifespan
-
Dickinson, A. G., Fraser, H. & Outram, G. W. Scrapie incubation time can exceed natural lifespan. Nature 256, 732-733 (1975).
-
(1975)
Nature
, vol.256
, pp. 732-733
-
-
Dickinson, A.G.1
Fraser, H.2
Outram, G.W.3
-
140
-
-
27744446721
-
Breaking an absolute species barrier: Transgenic mice expressing the mink PrP gene are susceptible to transmissible mink encephalopathy
-
Windl, O. et al. Breaking an absolute species barrier: transgenic mice expressing the mink PrP gene are susceptible to transmissible mink encephalopathy. J. Virol. 79, 14971-14975 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 14971-14975
-
-
Windl, O.1
-
141
-
-
77954972690
-
A molecular switch controls interspecies prion disease transmission in mice
-
Sigurdson, C. J. et al. A molecular switch controls interspecies prion disease transmission in mice. J. Clin. Invest. 120, 2590-2599 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2590-2599
-
-
Sigurdson, C.J.1
-
142
-
-
3943084181
-
Emerging principles of conformation-based prion inheritance
-
Chien, P., Weissman, J. S. & DePace, A. H. Emerging principles of conformation-based prion inheritance. Annu. Rev. Biochem. 73, 617-656 (2004).
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 617-656
-
-
Chien, P.1
Weissman, J.S.2
Depace, A.H.3
-
143
-
-
34249290108
-
Atomic structures of amyloid cross-β spines reveal varied steric zippers
-
Sawaya, M. R. et al. Atomic structures of amyloid cross-β spines reveal varied steric zippers. Nature 447, 453-457 (2007).
-
(2007)
Nature
, vol.447
, pp. 453-457
-
-
Sawaya, M.R.1
-
144
-
-
1842766124
-
Molecular basis of barriers for interspecies transmissibility of mammalian prions
-
Vanik, D. L., Surewicz, K. A. & Surewicz, W. K. Molecular basis of barriers for interspecies transmissibility of mammalian prions. Mol. Cell 14, 139-145 (2004).
-
(2004)
Mol. Cell
, vol.14
, pp. 139-145
-
-
Vanik, D.L.1
Surewicz, K.A.2
Surewicz, W.K.3
-
145
-
-
0034964442
-
+] "prions" that are crosstransmissible and susceptible beyond a species barrier through a quasi-prion state
-
+] "prions" that are crosstransmissible and susceptible beyond a species barrier through a quasi-prion state. Mol. Cell 7, 1121-1130 (2001).
-
(2001)
Mol. Cell
, vol.7
, pp. 1121-1130
-
-
Nakayashiki, T.1
Ebihara, K.2
Bannai, H.3
Nakamura, Y.4
-
146
-
-
77953522394
-
Genetic and epigenetic control of the efficiency and fidelity of cross-species prion transmission
-
Chen, B. et al. Genetic and epigenetic control of the efficiency and fidelity of cross-species prion transmission. Mol. Microbiol. 76, 1483-1499 (2010).
-
(2010)
Mol. Microbiol.
, vol.76
, pp. 1483-1499
-
-
Chen, B.1
-
147
-
-
62549130374
-
Prion variants and species barriers among Saccharomyces Ure2 proteins
-
Edskes, H. K., McCann, L. M., Hebert, A. M. & Wickner, R. B. Prion variants and species barriers among Saccharomyces Ure2 proteins. Genetics 181, 1159-1167 (2009).
-
(2009)
Genetics
, vol.181
, pp. 1159-1167
-
-
Edskes, H.K.1
McCann, L.M.2
Hebert, A.M.3
Wickner, R.B.4
-
148
-
-
76749102953
-
Distinct type of transmission barrier revealed by study of multiple prion determinants of Rnq1
-
Kadnar, M. L., Articov, G. & Derkatch, I. L. Distinct type of transmission barrier revealed by study of multiple prion determinants of Rnq1. PLoS Genet. 6, E1000824 (2010).
-
(2010)
PLoS Genet.
, vol.6
-
-
Kadnar, M.L.1
Articov, G.2
Derkatch, I.L.3
-
149
-
-
17044381327
-
Fibril conformation as the basis of species- and strain-dependent seeding specificity of mammalian prion amyloids
-
Jones, E. M. & Surewicz, W. K. Fibril conformation as the basis of species- and strain-dependent seeding specificity of mammalian prion amyloids. Cell 121, 63-72 (2005).
-
(2005)
Cell
, vol.121
, pp. 63-72
-
-
Jones, E.M.1
Surewicz, W.K.2
-
151
-
-
0014336086
-
Modification of a strain of mouse-adapted scrapie by passage through rats
-
Pattison, I. H. & Jones, K. M. Modification of a strain of mouse-adapted scrapie by passage through rats. Res. Vet. Sci. 9, 408-410 (1968).
-
(1968)
Res. Vet. Sci.
, vol.9
, pp. 408-410
-
-
Pattison, I.H.1
Jones, K.M.2
-
152
-
-
0024325787
-
The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice
-
Kimberlin, R. H., Walker, C. A. & Fraser, H. The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice. J. Gen. Virol. 70, 2017-2025 (1989).
-
(1989)
J. Gen. Virol.
, vol.70
, pp. 2017-2025
-
-
Kimberlin, R.H.1
Walker, C.A.2
Fraser, H.3
-
153
-
-
0023265523
-
Temporary and permanent modifications to a single strain of mouse scrapie on transmission to rats and hamsters
-
Kimberlin, R. H., Cole, S. & Walker, C. A. Temporary and permanent modifications to a single strain of mouse scrapie on transmission to rats and hamsters. J. Gen. Virol. 68, 1875-1881 (1987).
-
(1987)
J. Gen. Virol.
, vol.68
, pp. 1875-1881
-
-
Kimberlin, R.H.1
Cole, S.2
Walker, C.A.3
-
154
-
-
67649807925
-
Conformational switching within individual amyloid fibrils
-
Makarava, N., Ostapchenko, V. G., Savtchenko, R. & Baskakov, I. V. Conformational switching within individual amyloid fibrils. J. Biol. Chem. 284, 14386-14395 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 14386-14395
-
-
Makarava, N.1
Ostapchenko, V.G.2
Savtchenko, R.3
Baskakov, I.V.4
-
155
-
-
0348077417
-
A neuronal isoform of the Aplysia CPEB has prion-like properties
-
Si, K., Lindquist, S. & Kandel, E. R. A neuronal isoform of the Aplysia CPEB has prion-like properties. Cell 1 1 5, 879-891 (2003).
-
(2003)
Cell
, vol.11
, Issue.5
, pp. 879-891
-
-
Si, K.1
Lindquist, S.2
Kandel, E.R.3
-
156
-
-
23644453616
-
Lessons from a small Dispensable genome: The mitochondrial genome of yeast
-
Bernardi, G. Lessons from a small, Dispensable genome: the mitochondrial genome of yeast. Gene 354, 189-200 (2005).
-
(2005)
Gene
, vol.354
, pp. 189-200
-
-
Bernardi, G.1
-
157
-
-
24644444562
-
Primary sequence independence for prion formation
-
Ross, E. D., Edskes, H. K., Terry, M. J. & Wickner, R. B. Primary sequence independence for prion formation. Proc. Natl Acad. Sci. USA 102, 12825-12830 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 12825-12830
-
-
Ross, E.D.1
Edskes, H.K.2
Terry, M.J.3
Wickner, R.B.4
-
158
-
-
34250866206
-
A non-Q/N-rich prion domain of a foreign prion [Het-s] Can propagate as a prion in yeast
-
Taneja, V., Maddelein, M. L., Talarek, N., Saupe, S. J. & Liebman, S. W. A non-Q/N-rich prion domain of a foreign prion, [Het-s], Can propagate as a prion in yeast. Mol. Cell 27, 67-77 (2007).
-
(2007)
Mol. Cell
, vol.27
, pp. 67-77
-
-
Taneja, V.1
Maddelein, M.L.2
Talarek, N.3
Saupe, S.J.4
Liebman, S.W.5
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