Non-Mendelian determinant [ISP+] in yeast is a nuclear-residing prion form of the global transcriptional regulator Sfp1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 23, 2010, Pages 10573-10577

  Rogoza, Tatyana ^a   Goginashvili, Alexander ^a,b   Rodionova, Sofia ^a,c   Ivanov, Maxim ^a,d   Viktorovskaya, Olga ^a,e   Rubel, Alexander ^a   Volkov, Kirill ^a,f   Mironova, Ludmila ^a  

^a ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^b ETH ZURICH   (Switzerland)

^c INSTITUTE FOR INFORMATION TRANSMISSION PROBLEMS   (Russian Federation)

^d KAROLINSKA INSTITUTE   (Sweden)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^f GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Nonsense suppression; Protein inheritance

Indexed keywords

FUNGAL PROTEIN; PROTEIN SFP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; GENE DELETION; GENETIC TRANSCRIPTION; NONHUMAN; PHENOTYPE; PRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; YEAST;

CELL NUCLEUS; DNA-BINDING PROTEINS; GENE DELETION; PHENOTYPE; PRIONS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS;

SACCHAROMYCES CEREVISIAE;

EID: 77953767980     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1005949107     Document Type: Article

References (39)

1. Wickner RB, Edskes HK, Shewmaker F, Nakayashiki T (2007) Prions of fungi: Inherited structures and biological roles. Nat Rev Microbiol 5:611-618. (Pubitemid 47074116)
2. Du Z, Park KW, Yu H, Fan Q, Li L (2008) Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae. Nat Genet 40:460-465. (Pubitemid 351450881)
3. Nemecek J, Nakayashiki T, Wickner RB (2009) A prion of yeast metacaspase homolog (Mca1p) detected by a genetic screen. Proc Natl Acad Sci USA 106:1892-1896.
4. Patel BK, Gavin-Smyth J, Liebman SW (2009) The yeast global transcriptional corepressor protein Cyc8 can propagate as a prion. Nat Cell Biol 11:344-349.
5. Alberti S, Halfmann R, King O, Kapila A, Lindquist S (2009) A systematic survey identifies prions and illuminates sequence features of prionogenic proteins. Cell 137:146-158.
6. Roberts BT, Wickner RB (2003) Heritable activity: A prion that propagates by covalent autoactivation. Genes Dev 17:2083-2087.
7. Brown JC, Lindquist S (2009) A heritable switch in carbon source utilization driven by an unusual yeast prion. Genes Dev 23:2320-2332.
8. Wickner RB (1994) [URE3] as an altered URE2 protein: Evidence for a prion analog in Saccharomyces cerevisiae. Science 264:566-569.
9. Volkov KV, et al. (2002) Novel non-Mendelian determinant involved in the control of translation accuracy in Saccharomyces cerevisiae. Genetics 160:25-36.
10. +] in Saccharomyces cerevisiae depends on the combination of sup35 and sup45 mutations. Mol Biol (Mosk) 40:844-849.
11. Rogoza TM, et al. (2009) Search for the genes critical for propagation of the prion-like antisuppressordeterminant [ISP+] inyeastusing insertion library.MolBiol (Mosk) 43:392-399.
12. Wickner RB, et al. (2004) Prion genetics: New rules for a new kind of gene. Annu Rev Genet 38:681-707.
13. Romanova NV, Chernoff YO (2009) Hsp104 and prion propagation. Protein Pept Lett 16:598-605.
14. Wickner RB, et al. (2001) Yeast prions act as genes composed of self-propagating protein amyloids. Adv Protein Chem 57:313-334.
15. Marion RM, et al. (2004) Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression. Proc Natl Acad Sci USA 101:14315-14322.
16. Jorgensen P, et al. (2004) A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes Dev 18:2491-2505.
17. Blumberg H, Silver P (1991) A split zinc-finger protein is required for normal yeast growth. Gene 107:101-110.
18. Sudbery P (2002) Cell biology. When wee meets whi. Science 297:351-352.
19. Fingerman I, Nagaraj V, Norris D, Vershon AK (2003) Sfp1 plays a key role in yeast ribosome biogenesis. Eukaryot Cell 2:1061-1068.
20. Cipollina C, et al. (2008) Saccharomyces cerevisiae SFP1: At the crossroads of central metabolism and ribosome biogenesis. Microbiology 154:1686-1699.
21. Lempiäinen H, et al. (2009) Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling. Mol Cell 33:704-716.
22. Michelitsch MD, Weissman JS (2000) A census of glutamine/asparagine-rich regions: Implications for their conserved function and the prediction of novel prions.Proc Natl Acad Sci USA 97:11910-11915.
23. Harrison PM, Gerstein M (2003) A method to assess compositional bias in biological sequences and its application to prion-like glutamine/asparagine-rich domains in eukaryotic proteomes. Genome Biol 4:R40.
24. Lund PM, Cox BS (1981) Reversion analysis of [psi-] mutations in Saccharomyces cerevisiae. Genet Res 37:173-182.
25. Liu JJ, Lindquist S (1999) Oligopeptide-repeat expansions modulate 'protein-only' inheritance in yeast. Nature 400:573-576.
26. Tuite MF, Cox BS (2003) Propagation of yeast prions. Nat Rev Mol Cell Biol 4:878-890.
27. Grimminger V, Richter K, Imhof A, Buchner J, Walter S (2004) The prion curing agent guanidinium chloride specifically inhibits ATP hydrolysis by Hsp 104. J Biol Chem 279:7378-7383.
28. Crist CG, Nakayashiki T, Kurahashi H, Nakamura Y (2003) [PHI+], a novel Sup35-prion variant propagated with non-Gln/Asn oligopeptide repeats in the absence of the chaperone protein Hsp104. Genes Cells 8:603-618.
29. Saupe SJ (2007) A short history of small s: A prion of the fungus Podospora anserina. Prion 1:110-115.
30. +]. Cell 106:171-182.
31. Vitrenko YA, Gracheva EO, Richmond JE, Liebman SW (2007) Visualization of aggregation of the Rnq1 prion domain and cross-seeding interactions with Sup35NM. J Biol Chem 282:1779-1787.
32. Baxa U, Speransky V, Steven AC, Wickner RB (2002) Mechanism of inactivation on prion conversion of the Saccharomyces cerevisiae Ure2 protein. Proc Natl Acad Sci USA 99:5253-5260.
33. Derkatch IL, Liebman SW (2007) Prion-prion interactions. Prion 1:161-169.
34. Urakov VN, et al. (2010) Interdependence of amyloid formation in yeast: Implications for polyglutamine disorders and biological functions. Prion 4:45-52.
35. Chernoff YO, Newnam GP, Kumar J, Allen K, Zink AD (1999) Evidence for a protein mutator in yeast: Role of the Hsp70-related chaperone ssb in formation, stability, and toxicity of the [PSI] prion. Mol Cell Biol 19:8103-8112.
36. Storici F, Lewis LK, Resnick MA (2001) In vivo site-directed mutagenesis using oligonucleotides. Nat Biotechnol 19:773-776.
37. Kaiser C, Michaelis S, Mitchell A (1994) Methods in Yeast Genetics (Cold Spring Harbor Laboratory Press, Plainview, NY), p 234.
38. +] prion in Saccharomyces cerevisiae. Genetics 147:507-519.
39. Chernoff YO, Uptain SM, Lindquist SL (2002) Analysis of prion factors in yeast. Methods Enzymol 351:499-538.