Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis

Journal of Cell Biology

Volumn 161, Issue 3, 2003, Pages 521-533

  Berson, Joanne F ^a   Theos, Alexander C ^a   Harper, Dawn C ^a   Tenza, Danielle ^b   Raposo, Graga ^b   Marks, Michael S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CNRS   (France)

Author keywords

Endosome; Fibril; Furin; Lysosome related organelle; Proteolysis

Indexed keywords

AMYLOID; GLYCOPROTEIN; MEMBRANE PROTEIN; PROPROTEIN CONVERTASE; PROTEIN DERIVATIVE; PROTEIN PMEL17; UNCLASSIFIED DRUG;

ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; ENZYME DEGRADATION; HUMAN; HUMAN CELL; LYSOSOME; MELANOSOME; NUCLEOTIDE SEQUENCE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; REGULATORY MECHANISM; TISSUE SPECIFICITY;

CELL COMPARTMENTATION; CELL MEMBRANE; DETERGENTS; ENDOSOMES; EUKARYOTIC CELLS; GLYCOPROTEINS; HELA CELLS; HUMANS; INTRACELLULAR MEMBRANES; MELANINS; MELANOSOMES; MEMBRANE GLYCOPROTEINS; MICROFIBRILS; MICROSCOPY, ELECTRON; OCTOXYNOL; PEPTIDE HYDROLASES; PROPROTEIN CONVERTASES; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SOLUBILITY; SUBTILISINS;

EID: 0037986392     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200302072     Document Type: Article

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