The pattern of somatic hypermutation of Ig genes is altered when p53 is inactivated

Molecular Immunology

Volumn 47, Issue 16, 2010, Pages 2611-2618

  Ratnam, Sarayu ^a   Bozek, Grazyna ^a   Nicolae, Dan ^a   Storb, Ursula ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

AID; Ig genes; Knockout mice; P53; Pol eta; Pol iota; Somatic hypermutation

Indexed keywords

IMMUNOGLOBULIN; PROTEIN P53; RNA POLYMERASE; RNA POLYMERASE ETA SUBUNIT; RNA POLYMERASE IOTA SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ERYTHROCYTE; GENE DELETION; GENE FREQUENCY; GENE INACTIVATION; GENE REPLICATION; GENETIC TRANSCRIPTION; IMMUNIZATION; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SOMATIC HYPERMUTATION;

ANIMALS; DNA MISMATCH REPAIR; GENE EXPRESSION REGULATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; TUMOR SUPPRESSOR PROTEIN P53;

MUS; OVIS ARIES;

EID: 78649335719     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.05.291     Document Type: Article

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