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Volumn 95, Issue C, 2010, Pages 31-53

Targeting chemokine (C-C motif) Ligand 2 (CCL2) as an example of translation of cancer molecular biology to the clinic

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EID: 78649291412     PISSN: 18771173     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-385071-3.00003-4     Document Type: Chapter
Times cited : (77)

References (155)
  • 1
    • 0024538514 scopus 로고
    • Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants
    • T. Yoshimura, E.A. Robinson, S. Tanaka, E. Appella, J. Kuratsu, and E.J. Leonard Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants J Exp Med 169 1989 1449 1459
    • (1989) J Exp Med , vol.169 , pp. 1449-1459
    • Yoshimura, T.1    Robinson, E.A.2    Tanaka, S.3    Appella, E.4    Kuratsu, J.5    Leonard, E.J.6
  • 2
    • 0024508563 scopus 로고
    • Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line
    • K. Matsushima, C.G. Larsen, G.C. DuBois, and J.J. Oppenheim Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line J Exp Med 169 1989 1485 1490
    • (1989) J Exp Med , vol.169 , pp. 1485-1490
    • Matsushima, K.1    Larsen, C.G.2    Dubois, G.C.3    Oppenheim, J.J.4
  • 3
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • F. Balkwill Cancer and the chemokine network Nat Rev Cancer 4 2004 540 550
    • (2004) Nat Rev Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 4
    • 7244242357 scopus 로고    scopus 로고
    • Chemokines in the pathogenesis of vascular disease
    • I.F. Charo, and M.B. Taubman Chemokines in the pathogenesis of vascular disease Circ Res 95 2004 858 866
    • (2004) Circ Res , vol.95 , pp. 858-866
    • Charo, I.F.1    Taubman, M.B.2
  • 5
    • 0020623394 scopus 로고
    • Molecular cloning of gene sequences regulated by platelet-derived growth factor
    • B.H. Cochran, A.C. Reffel, and C.D. Stiles Molecular cloning of gene sequences regulated by platelet-derived growth factor Cell 33 1983 939 947
    • (1983) Cell , vol.33 , pp. 939-947
    • Cochran, B.H.1    Reffel, A.C.2    Stiles, C.D.3
  • 7
    • 0032833794 scopus 로고    scopus 로고
    • Regulated expression of MCP-1 by osteoblastic cells in vitro and in vivo
    • D.T. Graves, Y. Jiang, and A.J. Valente Regulated expression of MCP-1 by osteoblastic cells in vitro and in vivo Histol Histopathol 14 1999 1347 1354
    • (1999) Histol Histopathol , vol.14 , pp. 1347-1354
    • Graves, D.T.1    Jiang, Y.2    Valente, A.J.3
  • 9
    • 0028084818 scopus 로고
    • Regulation of monocyte chemoattractant protein-1 expression in adult human non-neoplastic astrocytes is sensitive to tumor necrosis factor (TNF) or antibody to the 55-kDa TNF receptor
    • B.P. Barna, J. Pettay, G.H. Barnett, P. Zhou, K. Iwasaki, and M.L. Estes Regulation of monocyte chemoattractant protein-1 expression in adult human non-neoplastic astrocytes is sensitive to tumor necrosis factor (TNF) or antibody to the 55-kDa TNF receptor J Neuroimmunol 50 1994 101 107
    • (1994) J Neuroimmunol , vol.50 , pp. 101-107
    • Barna, B.P.1    Pettay, J.2    Barnett, G.H.3    Zhou, P.4    Iwasaki, K.5    Estes, M.L.6
  • 10
    • 0026734895 scopus 로고
    • IL-1 receptor antagonist inhibits monocyte chemotactic peptide 1 generation by human mesangial cells
    • Z. Brown, R.M. Strieter, G.H. Neild, R.C. Thompson, S.L. Kunkel, and J. Westwick IL-1 receptor antagonist inhibits monocyte chemotactic peptide 1 generation by human mesangial cells Kidney Int 42 1992 95 101
    • (1992) Kidney Int , vol.42 , pp. 95-101
    • Brown, Z.1    Strieter, R.M.2    Neild, G.H.3    Thompson, R.C.4    Kunkel, S.L.5    Westwick, J.6
  • 11
    • 0025281588 scopus 로고
    • Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells
    • S.D. Cushing, J.A. Berliner, A.J. Valente, M.C. Territo, M. Navab, and F. Parhami Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells Proc Natl Acad Sci USA 87 1990 5134 5138
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5134-5138
    • Cushing, S.D.1    Berliner, J.A.2    Valente, A.J.3    Territo, M.C.4    Navab, M.5    Parhami, F.6
  • 12
    • 0025823107 scopus 로고
    • Alveolar macrophage-derived cytokines induce monocyte chemoattractant protein-1 expression from human pulmonary type II-like epithelial cells
    • T.J. Standiford, S.L. Kunkel, S.H. Phan, B.J. Rollins, and R.M. Strieter Alveolar macrophage-derived cytokines induce monocyte chemoattractant protein-1 expression from human pulmonary type II-like epithelial cells J Biol Chem 266 1991 9912 9918
    • (1991) J Biol Chem , vol.266 , pp. 9912-9918
    • Standiford, T.J.1    Kunkel, S.L.2    Phan, S.H.3    Rollins, B.J.4    Strieter, R.M.5
  • 13
    • 34547111029 scopus 로고    scopus 로고
    • PTHrP-induced MCP-1 production by human bone marrow endothelial cells and osteoblasts promotes osteoclast differentiation and prostate cancer cell proliferation and invasion in vitro
    • Y. Lu, G. Xiao, D.L. Galson, Y. Nishio, A. Mizokami, and E.T. Keller PTHrP-induced MCP-1 production by human bone marrow endothelial cells and osteoblasts promotes osteoclast differentiation and prostate cancer cell proliferation and invasion in vitro Int J Cancer 121 2007 724 733
    • (2007) Int J Cancer , vol.121 , pp. 724-733
    • Lu, Y.1    Xiao, G.2    Galson, D.L.3    Nishio, Y.4    Mizokami, A.5    Keller, E.T.6
  • 14
    • 0024505456 scopus 로고
    • Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE
    • T. Yoshimura, N. Yuhki, S.K. Moore, E. Appella, M.I. Lerman, and E.J. Leonard Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE FEBS Lett 244 1989 487 493
    • (1989) FEBS Lett , vol.244 , pp. 487-493
    • Yoshimura, T.1    Yuhki, N.2    Moore, S.K.3    Appella, E.4    Lerman, M.I.5    Leonard, E.J.6
  • 15
    • 77549086214 scopus 로고    scopus 로고
    • CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis
    • J. Zhang, L. Patel, and K.J. Pienta CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis Cytokine Growth Factor Rev 21 2010 41 48
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 41-48
    • Zhang, J.1    Patel, L.2    Pienta, K.J.3
  • 16
    • 77951631347 scopus 로고    scopus 로고
    • Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth
    • J. Zhang, Y. Lu, and K.J. Pienta Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth J Natl Cancer Inst 102 2010 522 528
    • (2010) J Natl Cancer Inst , vol.102 , pp. 522-528
    • Zhang, J.1    Lu, Y.2    Pienta, K.J.3
  • 17
    • 33846073087 scopus 로고    scopus 로고
    • CCL2 (Monocyte Chemoattractant Protein-1) in cancer bone metastases
    • M.J. Craig, and R.D. Loberg CCL2 (Monocyte Chemoattractant Protein-1) in cancer bone metastases Cancer Metastasis Rev 25 2006 611 619
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 611-619
    • Craig, M.J.1    Loberg, R.D.2
  • 18
    • 33748375788 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion
    • Y. Lu, Z. Cai, D.L. Galson, G. Xiao, Y. Liu, and D.E. George Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion Prostate 66 2006 1311 1318
    • (2006) Prostate , vol.66 , pp. 1311-1318
    • Lu, Y.1    Cai, Z.2    Galson, D.L.3    Xiao, G.4    Liu, Y.5    George, D.E.6
  • 19
    • 0030056544 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 gene expression in prostatic hyperplasia and prostate adenocarcinoma
    • L. Mazzucchelli, P. Loetscher, A. Kappeler, M. Uguccioni, M. Baggiolini, and J.A. Laissue Monocyte chemoattractant protein-1 gene expression in prostatic hyperplasia and prostate adenocarcinoma Am J Pathol 149 1996 501 509
    • (1996) Am J Pathol , vol.149 , pp. 501-509
    • Mazzucchelli, L.1    Loetscher, P.2    Kappeler, A.3    Uguccioni, M.4    Baggiolini, M.5    Laissue, J.A.6
  • 20
    • 0035341589 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in organ-confined prostate cancer by gene expression array
    • A. Chetcuti, S. Margan, S. Mann, P. Russell, D. Handelsman, and J. Rogers Identification of differentially expressed genes in organ-confined prostate cancer by gene expression array Prostate 47 2001 132 140
    • (2001) Prostate , vol.47 , pp. 132-140
    • Chetcuti, A.1    Margan, S.2    Mann, S.3    Russell, P.4    Handelsman, D.5    Rogers, J.6
  • 21
    • 33745954520 scopus 로고    scopus 로고
    • CCL2 is a potent regulator of prostate cancer cell migration and proliferation
    • R.D. Loberg, L.L. Day, J. Harwood, C. Ying, L.N. St John, and R. Giles CCL2 is a potent regulator of prostate cancer cell migration and proliferation Neoplasia 8 2006 578 586
    • (2006) Neoplasia , vol.8 , pp. 578-586
    • Loberg, R.D.1    Day, L.L.2    Harwood, J.3    Ying, C.4    St John, L.N.5    Giles, R.6
  • 22
    • 28844501340 scopus 로고    scopus 로고
    • The role of nuclear factor kappaB on angiogenesis regulation through monocyte chemotactic protein-1 in myeloma
    • S. Stifter The role of nuclear factor kappaB on angiogenesis regulation through monocyte chemotactic protein-1 in myeloma Med Hypotheses 66 2006 384 386
    • (2006) Med Hypotheses , vol.66 , pp. 384-386
    • Stifter, S.1
  • 23
    • 0028967734 scopus 로고
    • Tumor necrosis factor alpha and transforming growth factor beta upregulate astrocyte expression of monocyte chemoattractant protein-1
    • A.A. Hurwitz, W.D. Lyman, and J.W. Berman Tumor necrosis factor alpha and transforming growth factor beta upregulate astrocyte expression of monocyte chemoattractant protein-1 J Neuroimmunol 57 1995 193 198
    • (1995) J Neuroimmunol , vol.57 , pp. 193-198
    • Hurwitz, A.A.1    Lyman, W.D.2    Berman, J.W.3
  • 24
    • 1642413569 scopus 로고    scopus 로고
    • Transendothelial migration of myeloma cells is increased by tumor necrosis factor (TNF)-alpha via TNF receptor 2 and autocrine up-regulation of MCP-1
    • K. Johrer, K. Janke, J. Krugmann, M. Fiegl, and R. Greil Transendothelial migration of myeloma cells is increased by tumor necrosis factor (TNF)-alpha via TNF receptor 2 and autocrine up-regulation of MCP-1 Clin Cancer Res 10 2004 1901 1910
    • (2004) Clin Cancer Res , vol.10 , pp. 1901-1910
    • Johrer, K.1    Janke, K.2    Krugmann, J.3    Fiegl, M.4    Greil, R.5
  • 25
    • 18144393375 scopus 로고    scopus 로고
    • MCP-1 is induced by receptor activator of nuclear factor-{kappa}B ligand, promotes human osteoclast fusion, and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation
    • M.S. Kim, C.J. Day, and N.A. Morrison MCP-1 is induced by receptor activator of nuclear factor-{kappa}B ligand, promotes human osteoclast fusion, and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation J Biol Chem 280 2005 16163 16169
    • (2005) J Biol Chem , vol.280 , pp. 16163-16169
    • Kim, M.S.1    Day, C.J.2    Morrison, N.A.3
  • 26
    • 0037299220 scopus 로고    scopus 로고
    • Chemokine biology in cancer
    • F. Balkwill Chemokine biology in cancer Semin Immunol 15 2003 49 55
    • (2003) Semin Immunol , vol.15 , pp. 49-55
    • Balkwill, F.1
  • 27
    • 0030699387 scopus 로고    scopus 로고
    • Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
    • T. Kurihara, G. Warr, J. Loy, and R. Bravo Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor J Exp Med 186 1997 1757 1762
    • (1997) J Exp Med , vol.186 , pp. 1757-1762
    • Kurihara, T.1    Warr, G.2    Loy, J.3    Bravo, R.4
  • 28
    • 0031894801 scopus 로고    scopus 로고
    • Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model
    • M.N. Ajuebor, R.J. Flower, R. Hannon, M. Christie, K. Bowers, and A. Verity Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model J Leukoc Biol 63 1998 108 116
    • (1998) J Leukoc Biol , vol.63 , pp. 108-116
    • Ajuebor, M.N.1    Flower, R.J.2    Hannon, R.3    Christie, M.4    Bowers, K.5    Verity, A.6
  • 29
    • 0035903305 scopus 로고    scopus 로고
    • Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development
    • I. Kurth, K. Willimann, P. Schaerli, T. Hunziker, I. Clark-Lewis, and B. Moser Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development J Exp Med 194 2001 855 861
    • (2001) J Exp Med , vol.194 , pp. 855-861
    • Kurth, I.1    Willimann, K.2    Schaerli, P.3    Hunziker, T.4    Clark-Lewis, I.5    Moser, B.6
  • 30
    • 0028814819 scopus 로고
    • Monocyte chemotactic protein expression during schistosome egg granuloma formation. Sequence of production, localization, contribution, and regulation
    • S.W. Chensue, K.S. Warmington, N.W. Lukacs, P.M. Lincoln, M.D. Burdick, and R.M. Strieter Monocyte chemotactic protein expression during schistosome egg granuloma formation. Sequence of production, localization, contribution, and regulation Am J Pathol 146 1995 130 138
    • (1995) Am J Pathol , vol.146 , pp. 130-138
    • Chensue, S.W.1    Warmington, K.S.2    Lukacs, N.W.3    Lincoln, P.M.4    Burdick, M.D.5    Strieter, R.M.6
  • 31
    • 0030588642 scopus 로고    scopus 로고
    • Role of monocyte chemoattractant protein-1 (MCP-1) in Th1 (mycobacterial) and Th2 (schistosomal) antigen-induced granuloma formation: Relationship to local inflammation, Th cell expression, and IL-12 production
    • S.W. Chensue, K.S. Warmington, J.H. Ruth, P.S. Sanghi, P. Lincoln, and S.L. Kunkel Role of monocyte chemoattractant protein-1 (MCP-1) in Th1 (mycobacterial) and Th2 (schistosomal) antigen-induced granuloma formation: relationship to local inflammation, Th cell expression, and IL-12 production J Immunol 157 1996 4602 4608
    • (1996) J Immunol , vol.157 , pp. 4602-4608
    • Chensue, S.W.1    Warmington, K.S.2    Ruth, J.H.3    Sanghi, P.S.4    Lincoln, P.5    Kunkel, S.L.6
  • 32
    • 0029665212 scopus 로고    scopus 로고
    • Heteronuclear (1H, 13C, 15N) NMR assignments and solution structure of the monocyte chemoattractant protein-1 (MCP-1) dimer
    • T.M. Handel, and P.J. Domaille Heteronuclear (1H, 13C, 15N) NMR assignments and solution structure of the monocyte chemoattractant protein-1 (MCP-1) dimer Biochemistry 35 1996 6569 6584
    • (1996) Biochemistry , vol.35 , pp. 6569-6584
    • Handel, T.M.1    Domaille, P.J.2
  • 33
    • 0032490569 scopus 로고    scopus 로고
    • The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness
    • J.A. Gonzalo, C.M. Lloyd, D. Wen, J.P. Albar, T.N. Wells, and A. Proudfoot The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness J Exp Med 188 1998 157 167
    • (1998) J Exp Med , vol.188 , pp. 157-167
    • Gonzalo, J.A.1    Lloyd, C.M.2    Wen, D.3    Albar, J.P.4    Wells, T.N.5    Proudfoot, A.6
  • 34
    • 0034704593 scopus 로고    scopus 로고
    • Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1
    • L. Gu, S. Tseng, R.M. Horner, C. Tam, M. Loda, and B.J. Rollins Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1 Nature 404 2000 407 411
    • (2000) Nature , vol.404 , pp. 407-411
    • Gu, L.1    Tseng, S.2    Horner, R.M.3    Tam, C.4    Loda, M.5    Rollins, B.J.6
  • 35
    • 0031131879 scopus 로고    scopus 로고
    • Differential CC chemokine-induced enhancement of T helper cell cytokine production
    • W.J. Karpus, N.W. Lukacs, K.J. Kennedy, W.S. Smith, S.D. Hurst, and T.A. Barrett Differential CC chemokine-induced enhancement of T helper cell cytokine production J Immunol 158 1997 4129 4136
    • (1997) J Immunol , vol.158 , pp. 4129-4136
    • Karpus, W.J.1    Lukacs, N.W.2    Kennedy, K.J.3    Smith, W.S.4    Hurst, S.D.5    Barrett, T.A.6
  • 36
    • 20944449211 scopus 로고    scopus 로고
    • CCL2/monocyte chemoattractant protein-1 regulates inflammatory responses critical to healing myocardial infarcts
    • O. Dewald, P. Zymek, K. Winkelmann, A. Koerting, G. Ren, and T. Abou-Khamis CCL2/monocyte chemoattractant protein-1 regulates inflammatory responses critical to healing myocardial infarcts Circ Res 96 2005 881 889
    • (2005) Circ Res , vol.96 , pp. 881-889
    • Dewald, O.1    Zymek, P.2    Winkelmann, K.3    Koerting, A.4    Ren, G.5    Abou-Khamis, T.6
  • 37
    • 0032572719 scopus 로고    scopus 로고
    • Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis
    • L. Boring, J. Gosling, M. Cleary, and I.F. Charo Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis Nature 394 1998 894 897
    • (1998) Nature , vol.394 , pp. 894-897
    • Boring, L.1    Gosling, J.2    Cleary, M.3    Charo, I.F.4
  • 38
    • 0036141989 scopus 로고    scopus 로고
    • Local overexpression of monocyte chemoattractant protein-1 at vessel wall induces infiltration of macrophages and formation of atherosclerotic lesion: Synergism with hypercholesterolemia
    • M. Namiki, S. Kawashima, T. Yamashita, M. Ozaki, T. Hirase, and T. Ishida Local overexpression of monocyte chemoattractant protein-1 at vessel wall induces infiltration of macrophages and formation of atherosclerotic lesion: synergism with hypercholesterolemia Arterioscler Thromb Vasc Biol 22 2002 115 120
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 115-120
    • Namiki, M.1    Kawashima, S.2    Yamashita, T.3    Ozaki, M.4    Hirase, T.5    Ishida, T.6
  • 39
    • 0034596949 scopus 로고    scopus 로고
    • Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
    • L. Izikson, R.S. Klein, I.F. Charo, H.L. Weiner, and A.D. Luster Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2 J Exp Med 192 2000 1075 1080
    • (2000) J Exp Med , vol.192 , pp. 1075-1080
    • Izikson, L.1    Klein, R.S.2    Charo, I.F.3    Weiner, H.L.4    Luster, A.D.5
  • 40
    • 49149086594 scopus 로고    scopus 로고
    • Inhibition of monocyte chemoattractant protein-1 ameliorates rat adjuvant-induced arthritis
    • S. Shahrara, A.E. Proudfoot, C.C. Park, M.V. Volin, G.K. Haines, and J.M. Woods Inhibition of monocyte chemoattractant protein-1 ameliorates rat adjuvant-induced arthritis J Immunol 180 2008 3447 3456
    • (2008) J Immunol , vol.180 , pp. 3447-3456
    • Shahrara, S.1    Proudfoot, A.E.2    Park, C.C.3    Volin, M.V.4    Haines, G.K.5    Woods, J.M.6
  • 41
    • 10244225246 scopus 로고    scopus 로고
    • Intervention of crescentic glomerulonephritis by antibodies to monocyte chemotactic and activating factor (MCAF/MCP-1)
    • T. Wada, H. Yokoyama, K. Furuichi, K.I. Kobayashi, K. Harada, and M. Naruto Intervention of crescentic glomerulonephritis by antibodies to monocyte chemotactic and activating factor (MCAF/MCP-1) FASEB J 10 1996 1418 1425
    • (1996) FASEB J , vol.10 , pp. 1418-1425
    • Wada, T.1    Yokoyama, H.2    Furuichi, K.3    Kobayashi, K.I.4    Harada, K.5    Naruto, M.6
  • 42
    • 0031827453 scopus 로고    scopus 로고
    • MCAF/MCP-1 protein expression in a rat model for pulmonary hypertension induced by monocrotaline
    • Y. Kasahara, H. Kimura, K. Kurosu, K. Sugito, N. Mukaida, and K. Matsushima MCAF/MCP-1 protein expression in a rat model for pulmonary hypertension induced by monocrotaline Chest 114 1998 67S
    • (1998) Chest , vol.114
    • Kasahara, Y.1    Kimura, H.2    Kurosu, K.3    Sugito, K.4    Mukaida, N.5    Matsushima, K.6
  • 44
    • 0030896446 scopus 로고    scopus 로고
    • Monocyte recruitment and expression of monocyte chemoattractant protein-1 are developmentally regulated in remodeling bone in the mouse
    • S. Volejnikova, M. Laskari, S.C. Marks Jr., and D.T. Graves Monocyte recruitment and expression of monocyte chemoattractant protein-1 are developmentally regulated in remodeling bone in the mouse Am J Pathol 150 1997 1711 1721
    • (1997) Am J Pathol , vol.150 , pp. 1711-1721
    • Volejnikova, S.1    Laskari, M.2    Marks, Jr.S.C.3    Graves, D.T.4
  • 45
    • 33644854945 scopus 로고    scopus 로고
    • MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkappaB ligand for bone resorption
    • M.S. Kim, C.J. Day, C.I. Selinger, C.L. Magno, S.R. Stephens, and N.A. Morrison MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkappaB ligand for bone resorption J Biol Chem 281 2006 1274 1285
    • (2006) J Biol Chem , vol.281 , pp. 1274-1285
    • Kim, M.S.1    Day, C.J.2    Selinger, C.I.3    Magno, C.L.4    Stephens, S.R.5    Morrison, N.A.6
  • 46
    • 0028173975 scopus 로고
    • Macrophage inflammatory protein-1 alpha and monocyte chemoattractant peptide-1 elicit immediate and late cutaneous reactions and activate murine mast cells in vivo
    • R. Alam, D. Kumar, D. Anderson-Walters, and P.A. Forsythe Macrophage inflammatory protein-1 alpha and monocyte chemoattractant peptide-1 elicit immediate and late cutaneous reactions and activate murine mast cells in vivo J Immunol 152 1994 1298 1303
    • (1994) J Immunol , vol.152 , pp. 1298-1303
    • Alam, R.1    Kumar, D.2    Anderson-Walters, D.3    Forsythe, P.A.4
  • 47
    • 0028963288 scopus 로고
    • Bone marrow-derived murine mast cells migrate, but do not degranulate, in response to chemokines
    • D. Taub, J. Dastych, N. Inamura, J. Upton, D. Kelvin, and D. Metcalfe Bone marrow-derived murine mast cells migrate, but do not degranulate, in response to chemokines J Immunol 154 1995 2393 2402
    • (1995) J Immunol , vol.154 , pp. 2393-2402
    • Taub, D.1    Dastych, J.2    Inamura, N.3    Upton, J.4    Kelvin, D.5    Metcalfe, D.6
  • 48
    • 0029131375 scopus 로고
    • Cytokines involved in growth and differentiation of human basophils and mast cells
    • P. Valent Cytokines involved in growth and differentiation of human basophils and mast cells Exp Dermatol 4 1995 255 259
    • (1995) Exp Dermatol , vol.4 , pp. 255-259
    • Valent, P.1
  • 49
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • J.W. Pollard Tumour-educated macrophages promote tumour progression and metastasis Nat Rev Cancer 4 2004 71 78
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 50
    • 0035871633 scopus 로고    scopus 로고
    • Enhanced airway Th2 response after allergen challenge in mice deficient in CC chemokine receptor-2 (CCR2)
    • Y. Kim, S. Sung, W.A. Kuziel, S. Feldman, S.M. Fu, and C.E. Rose Jr. Enhanced airway Th2 response after allergen challenge in mice deficient in CC chemokine receptor-2 (CCR2) J Immunol 166 2001 5183 5192
    • (2001) J Immunol , vol.166 , pp. 5183-5192
    • Kim, Y.1    Sung, S.2    Kuziel, W.A.3    Feldman, S.4    Fu, S.M.5    Rose, Jr.C.E.6
  • 51
    • 0034234623 scopus 로고    scopus 로고
    • Human endothelial cells express CCR2 and respond to MCP-1: Direct role of MCP-1 in angiogenesis and tumor progression
    • R. Salcedo, M.L. Ponce, H.A. Young, K. Wasserman, J.M. Ward, and H.K. Kleinman Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression Blood 96 2000 34 40
    • (2000) Blood , vol.96 , pp. 34-40
    • Salcedo, R.1    Ponce, M.L.2    Young, H.A.3    Wasserman, K.4    Ward, J.M.5    Kleinman, H.K.6
  • 52
    • 29144443977 scopus 로고    scopus 로고
    • Chemokine receptor CCR2 expression by systemic sclerosis fibroblasts: Evidence for autocrine regulation of myofibroblast differentiation
    • M.T. Carulli, V.H. Ong, M. Ponticos, X. Shiwen, D.J. Abraham, and C.M. Black Chemokine receptor CCR2 expression by systemic sclerosis fibroblasts: evidence for autocrine regulation of myofibroblast differentiation Arthritis Rheum 52 2005 3772 3782
    • (2005) Arthritis Rheum , vol.52 , pp. 3772-3782
    • Carulli, M.T.1    Ong, V.H.2    Ponticos, M.3    Shiwen, X.4    Abraham, D.J.5    Black, C.M.6
  • 53
    • 37549036588 scopus 로고    scopus 로고
    • Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment
    • A.H. Klopp, E.L. Spaeth, J.L. Dembinski, W.A. Woodward, A. Munshi, and R.E. Meyn Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment Cancer Res 67 2007 11687 11695
    • (2007) Cancer Res , vol.67 , pp. 11687-11695
    • Klopp, A.H.1    Spaeth, E.L.2    Dembinski, J.L.3    Woodward, W.A.4    Munshi, A.5    Meyn, R.E.6
  • 54
    • 34247855834 scopus 로고    scopus 로고
    • CCR2 expression correlates with prostate cancer progression
    • Y. Lu, Z. Cai, G. Xiao, Y. Liu, E.T. Keller, and Z. Yao CCR2 expression correlates with prostate cancer progression J Cell Biochem 101 2007 676 685
    • (2007) J Cell Biochem , vol.101 , pp. 676-685
    • Lu, Y.1    Cai, Z.2    Xiao, G.3    Liu, Y.4    Keller, E.T.5    Yao, Z.6
  • 55
    • 35148852659 scopus 로고    scopus 로고
    • Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo
    • R.D. Loberg, C. Ying, M. Craig, L.L. Day, E. Sargent, and C. Neeley Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo Cancer Res 67 2007 9417 9424
    • (2007) Cancer Res , vol.67 , pp. 9417-9424
    • Loberg, R.D.1    Ying, C.2    Craig, M.3    Day, L.L.4    Sargent, E.5    Neeley, C.6
  • 56
    • 67649400529 scopus 로고    scopus 로고
    • Recent developments in CCR2 antagonists
    • M. Xia, and Z. Sui Recent developments in CCR2 antagonists Expert Opin Ther Pat 19 2009 295 303
    • (2009) Expert Opin Ther Pat , vol.19 , pp. 295-303
    • Xia, M.1    Sui, Z.2
  • 57
    • 64449083350 scopus 로고    scopus 로고
    • Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis
    • N.B. Binder, B. Niederreiter, O. Hoffmann, R. Stange, T. Pap, and T.M. Stulnig Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis Nat Med 15 2009 417 424
    • (2009) Nat Med , vol.15 , pp. 417-424
    • Binder, N.B.1    Niederreiter, B.2    Hoffmann, O.3    Stange, R.4    Pap, T.5    Stulnig, T.M.6
  • 58
    • 60449090099 scopus 로고    scopus 로고
    • Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone
    • Y. Lu, Q. Chen, E. Corey, W. Xie, J. Fan, and A. Mizokami Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone Clin Exp Metastasis 26 2009 161 169
    • (2009) Clin Exp Metastasis , vol.26 , pp. 161-169
    • Lu, Y.1    Chen, Q.2    Corey, E.3    Xie, W.4    Fan, J.5    Mizokami, A.6
  • 59
    • 0026344131 scopus 로고
    • A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide
    • H. Juppner, A.B. Abou-Samra, M. Freeman, X.F. Kong, E. Schipani, and J. Richards A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide Science 254 1991 1024 1026
    • (1991) Science , vol.254 , pp. 1024-1026
    • Juppner, H.1    Abou-Samra, A.B.2    Freeman, M.3    Kong, X.F.4    Schipani, E.5    Richards, J.6
  • 60
    • 0026469089 scopus 로고
    • Parathyroid hormone-related protein: Structure, function, and measurement
    • W.J. Burtis Parathyroid hormone-related protein: structure, function, and measurement Clin Chem 38 1992 2171 2183
    • (1992) Clin Chem , vol.38 , pp. 2171-2183
    • Burtis, W.J.1
  • 62
    • 0027299741 scopus 로고
    • Immunohistochemical localization of parathyroid hormone-related protein in human prostate cancer
    • M. Iwamura, P.A. di Sant'Agnese, G. Wu, C.M. Benning, A.T. Cockett, and L.J. Deftos Immunohistochemical localization of parathyroid hormone-related protein in human prostate cancer Cancer Res 53 1993 1724 1726
    • (1993) Cancer Res , vol.53 , pp. 1724-1726
    • Iwamura, M.1    Di Sant'Agnese, P.A.2    Wu, G.3    Benning, C.M.4    Cockett, A.T.5    Deftos, L.J.6
  • 63
    • 0029045326 scopus 로고
    • Immunohistochemical localization of parathyroid hormone-related protein in prostatic intraepithelial neoplasia
    • M. Iwamura, S. Gershagen, O. Lapets, R. Moynes, P.A. Abrahamsson, and A.T. Cockett Immunohistochemical localization of parathyroid hormone-related protein in prostatic intraepithelial neoplasia Hum Pathol 26 1995 797 801
    • (1995) Hum Pathol , vol.26 , pp. 797-801
    • Iwamura, M.1    Gershagen, S.2    Lapets, O.3    Moynes, R.4    Abrahamsson, P.A.5    Cockett, A.T.6
  • 65
    • 0036244042 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein (PTHrP)-(1-139) isoform is efficiently secreted in vitro and enhances breast cancer metastasis to bone in vivo
    • T.A. Guise, J.J. Yin, R.J. Thomas, M. Dallas, Y. Cui, and M.T. Gillespie Parathyroid hormone-related protein (PTHrP)-(1-139) isoform is efficiently secreted in vitro and enhances breast cancer metastasis to bone in vivo Bone 30 2002 670 676
    • (2002) Bone , vol.30 , pp. 670-676
    • Guise, T.A.1    Yin, J.J.2    Thomas, R.J.3    Dallas, M.4    Cui, Y.5    Gillespie, M.T.6
  • 66
    • 0032918414 scopus 로고    scopus 로고
    • TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
    • J.J. Yin, K. Selander, J.M. Chirgwin, M. Dallas, B.G. Grubbs, and R. Wieser TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development J Clin Invest 103 1999 197 206
    • (1999) J Clin Invest , vol.103 , pp. 197-206
    • Yin, J.J.1    Selander, K.2    Chirgwin, J.M.3    Dallas, M.4    Grubbs, B.G.5    Wieser, R.6
  • 67
    • 0032609185 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein: A developmental regulatory molecule necessary for mammary gland development
    • M.E. Dunbar, and J.J. Wysolmerski Parathyroid hormone-related protein: a developmental regulatory molecule necessary for mammary gland development J Mammary Gland Biol Neoplasia 4 1999 21 34
    • (1999) J Mammary Gland Biol Neoplasia , vol.4 , pp. 21-34
    • Dunbar, M.E.1    Wysolmerski, J.J.2
  • 68
    • 0033011428 scopus 로고    scopus 로고
    • The parathyroid hormone-related protein (PTHrP) gene: Use of downstream TATA promotor and PTHrP 1-139 coding pathways in primary breast cancers vary with the occurrence of bone metastasis
    • Z. Bouizar, F. Spyratos, and M.C. De vernejoul The parathyroid hormone-related protein (PTHrP) gene: use of downstream TATA promotor and PTHrP 1-139 coding pathways in primary breast cancers vary with the occurrence of bone metastasis J Bone Miner Res 14 1999 406 414
    • (1999) J Bone Miner Res , vol.14 , pp. 406-414
    • Bouizar, Z.1    Spyratos, F.2    De Vernejoul, M.C.3
  • 69
    • 36348953061 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclasts
    • X. Li, L. Qin, M. Bergenstock, L.M. Bevelock, D.V. Novack, and N.C. Partridge Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclasts J Biol Chem 282 2007 33098 33106
    • (2007) J Biol Chem , vol.282 , pp. 33098-33106
    • Li, X.1    Qin, L.2    Bergenstock, M.3    Bevelock, L.M.4    Novack, D.V.5    Partridge, N.C.6
  • 70
    • 53449091768 scopus 로고    scopus 로고
    • Tumor expressed PTHrP facilitates prostate cancer-induced osteoblastic lesions
    • J. Liao, X. Li, A.J. Koh, J.E. Berry, N. Thudi, and T.J. Rosol Tumor expressed PTHrP facilitates prostate cancer-induced osteoblastic lesions Int J Cancer 123 2008 2267 2278
    • (2008) Int J Cancer , vol.123 , pp. 2267-2278
    • Liao, J.1    Li, X.2    Koh, A.J.3    Berry, J.E.4    Thudi, N.5    Rosol, T.J.6
  • 71
    • 60549088318 scopus 로고    scopus 로고
    • A destructive cascade mediated by CCL2 facilitates prostate cancer growth in bone
    • X. Li, R. Loberg, J. Liao, C. Ying, L.A. Snyder, and K.J. Pienta A destructive cascade mediated by CCL2 facilitates prostate cancer growth in bone Cancer Res 69 2009 1685 1692
    • (2009) Cancer Res , vol.69 , pp. 1685-1692
    • Li, X.1    Loberg, R.2    Liao, J.3    Ying, C.4    Snyder, L.A.5    Pienta, K.J.6
  • 72
    • 0037184101 scopus 로고    scopus 로고
    • Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells
    • O. Sekine, Y. Nishio, K. Egawa, T. Nakamura, H. Maegawa, and A. Kashiwagi Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells J Biol Chem 277 2002 36631 36639
    • (2002) J Biol Chem , vol.277 , pp. 36631-36639
    • Sekine, O.1    Nishio, Y.2    Egawa, K.3    Nakamura, T.4    Maegawa, H.5    Kashiwagi, A.6
  • 73
    • 0028169447 scopus 로고
    • NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene
    • A. Ueda, K. Okuda, S. Ohno, A. Shirai, T. Igarashi, and K. Matsunaga NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene J Immunol 153 1994 2052 2063
    • (1994) J Immunol , vol.153 , pp. 2052-2063
    • Ueda, A.1    Okuda, K.2    Ohno, S.3    Shirai, A.4    Igarashi, T.5    Matsunaga, K.6
  • 74
    • 0037320840 scopus 로고    scopus 로고
    • Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats
    • E.D. Milligan, C. Twining, M. Chacur, J. Biedenkapp, K. O'Connor, and S. Poole Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats J Neurosci 23 2003 1026 1040
    • (2003) J Neurosci , vol.23 , pp. 1026-1040
    • Milligan, E.D.1    Twining, C.2    Chacur, M.3    Biedenkapp, J.4    O'Connor, K.5    Poole, S.6
  • 75
    • 3242725996 scopus 로고    scopus 로고
    • Peri-sciatic proinflammatory cytokines, reactive oxygen species, and complement induce mirror-image neuropathic pain in rats
    • C.M. Twining, E.M. Sloane, E.D. Milligan, M. Chacur, D. Martin, and S. Poole Peri-sciatic proinflammatory cytokines, reactive oxygen species, and complement induce mirror-image neuropathic pain in rats Pain 110 2004 299 309
    • (2004) Pain , vol.110 , pp. 299-309
    • Twining, C.M.1    Sloane, E.M.2    Milligan, E.D.3    Chacur, M.4    Martin, D.5    Poole, S.6
  • 76
    • 37449017192 scopus 로고    scopus 로고
    • Activation of the nuclear factor of activated T-cells (NFAT) mediates upregulation of CCR2 chemokine receptors in dorsal root ganglion (DRG) neurons: A possible mechanism for activity-dependent transcription in DRG neurons in association with neuropathic pain
    • H. Jung, and R.J. Miller Activation of the nuclear factor of activated T-cells (NFAT) mediates upregulation of CCR2 chemokine receptors in dorsal root ganglion (DRG) neurons: a possible mechanism for activity-dependent transcription in DRG neurons in association with neuropathic pain Mol Cell Neurosci 37 2008 170 177
    • (2008) Mol Cell Neurosci , vol.37 , pp. 170-177
    • Jung, H.1    Miller, R.J.2
  • 77
    • 76149128694 scopus 로고    scopus 로고
    • CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel-induced cytotoxicity
    • D.Z. Qian, B.L. Rademacher, J. Pittsenbarger, C.Y. Huang, A. Myrthue, and C.S. Higano CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel-induced cytotoxicity Prostate 70 2010 433 442
    • (2010) Prostate , vol.70 , pp. 433-442
    • Qian, D.Z.1    Rademacher, B.L.2    Pittsenbarger, J.3    Huang, C.Y.4    Myrthue, A.5    Higano, C.S.6
  • 78
    • 28844463087 scopus 로고    scopus 로고
    • Differential signaling mechanisms regulate expression of CC chemokine receptor-2 during monocyte maturation
    • R.J. Phillips, M. Lutz, and B. Premack Differential signaling mechanisms regulate expression of CC chemokine receptor-2 during monocyte maturation J Inflamm (Lond) 2 2005 14
    • (2005) J Inflamm (Lond) , vol.2 , pp. 14
    • Phillips, R.J.1    Lutz, M.2    Premack, B.3
  • 79
    • 19344367429 scopus 로고    scopus 로고
    • The mouse CCR2 gene is regulated by two promoters that are responsive to plasma cholesterol and peroxisome proliferator-activated receptor gamma ligands
    • Y. Chen, S.R. Green, J. Ho, A. Li, F. Almazan, and O. Quehenberger The mouse CCR2 gene is regulated by two promoters that are responsive to plasma cholesterol and peroxisome proliferator-activated receptor gamma ligands Biochem Biophys Res Commun 332 2005 188 193
    • (2005) Biochem Biophys Res Commun , vol.332 , pp. 188-193
    • Chen, Y.1    Green, S.R.2    Ho, J.3    Li, A.4    Almazan, F.5    Quehenberger, O.6
  • 80
    • 0041381158 scopus 로고    scopus 로고
    • TNF-alpha microinjection upregulates chemokines and chemokine receptors in the central nervous system without inducing leukocyte infiltration
    • A.R. Glabinski, B. Bielecki, P. Kolodziejski, Y. Han, K. Selmaj, and R.M. Ransohoff TNF-alpha microinjection upregulates chemokines and chemokine receptors in the central nervous system without inducing leukocyte infiltration J Interferon Cytokine Res 23 2003 457 466
    • (2003) J Interferon Cytokine Res , vol.23 , pp. 457-466
    • Glabinski, A.R.1    Bielecki, B.2    Kolodziejski, P.3    Han, Y.4    Selmaj, K.5    Ransohoff, R.M.6
  • 81
    • 0033582412 scopus 로고    scopus 로고
    • Cloning and functional characterization of the 5′-flanking region of the human monocyte chemoattractant protein-1 receptor (CCR2) gene. Essential role of 5′-untranslated region in tissue-specific expression
    • K. Yamamoto, H. Takeshima, K. Hamada, M. Nakao, T. Kino, and T. Nishi Cloning and functional characterization of the 5′-flanking region of the human monocyte chemoattractant protein-1 receptor (CCR2) gene. Essential role of 5′-untranslated region in tissue-specific expression J Biol Chem 274 1999 4646 4654
    • (1999) J Biol Chem , vol.274 , pp. 4646-4654
    • Yamamoto, K.1    Takeshima, H.2    Hamada, K.3    Nakao, M.4    Kino, T.5    Nishi, T.6
  • 82
    • 0037074883 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase and p70 S6 kinase regulate long-term potentiation in hippocampal neurons
    • C.R. Raymond, S.J. Redman, and M.F. Crouch The phosphoinositide 3-kinase and p70 S6 kinase regulate long-term potentiation in hippocampal neurons Neuroscience 109 2002 531 536
    • (2002) Neuroscience , vol.109 , pp. 531-536
    • Raymond, C.R.1    Redman, S.J.2    Crouch, M.F.3
  • 83
    • 11144292658 scopus 로고    scopus 로고
    • Site-directed mutagenesis of CCR2 identified amino acid residues in transmembrane helices 1, 2, and 7 important for MCP-1 binding and biological functions
    • M.A. Gavrilin, I.V. Gulina, T. Kawano, S. Dragan, L. Chakravarti, and P.E. Kolattukudy Site-directed mutagenesis of CCR2 identified amino acid residues in transmembrane helices 1, 2, and 7 important for MCP-1 binding and biological functions Biochem Biophys Res Commun 327 2005 533 540
    • (2005) Biochem Biophys Res Commun , vol.327 , pp. 533-540
    • Gavrilin, M.A.1    Gulina, I.V.2    Kawano, T.3    Dragan, S.4    Chakravarti, L.5    Kolattukudy, P.E.6
  • 84
    • 23944454929 scopus 로고    scopus 로고
    • Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis
    • Y. Terashima, N. Onai, M. Murai, M. Enomoto, V. Poonpiriya, and T. Hamada Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis Nat Immunol 6 2005 827 835
    • (2005) Nat Immunol , vol.6 , pp. 827-835
    • Terashima, Y.1    Onai, N.2    Murai, M.3    Enomoto, M.4    Poonpiriya, V.5    Hamada, T.6
  • 85
    • 33947511583 scopus 로고    scopus 로고
    • A novel activator of C-C chemokine, FROUNT, is expressed with C-C chemokine receptor 2 and its ligand in failing human heart
    • M. Satoh, T. Akatsu, Y. Ishkawa, Y. Minami, and M. Nakamura A novel activator of C-C chemokine, FROUNT, is expressed with C-C chemokine receptor 2 and its ligand in failing human heart J Card Fail 13 2007 114 119
    • (2007) J Card Fail , vol.13 , pp. 114-119
    • Satoh, M.1    Akatsu, T.2    Ishkawa, Y.3    Minami, Y.4    Nakamura, M.5
  • 86
    • 27844506524 scopus 로고    scopus 로고
    • Akt-regulated pathways in prostate cancer
    • P.K. Majumder, and W.R. Sellers Akt-regulated pathways in prostate cancer Oncogene 24 2005 7465 7474
    • (2005) Oncogene , vol.24 , pp. 7465-7474
    • Majumder, P.K.1    Sellers, W.R.2
  • 87
    • 0034526276 scopus 로고    scopus 로고
    • Impairment of erbB1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells
    • X. Zi, R.P. Singh, and R. Agarwal Impairment of erbB1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells Carcinogenesis 21 2000 2225 2235
    • (2000) Carcinogenesis , vol.21 , pp. 2225-2235
    • Zi, X.1    Singh, R.P.2    Agarwal, R.3
  • 88
    • 0034455310 scopus 로고    scopus 로고
    • Overexpression of insulin-like growth factor binding protein-5 helps accelerate progression to androgen-independence in the human prostate LNCaP tumor model through activation of phosphatidylinositol 3′-kinase pathway
    • H. Miyake, C. Nelson, P.S. Rennie, and M.E. Gleave Overexpression of insulin-like growth factor binding protein-5 helps accelerate progression to androgen-independence in the human prostate LNCaP tumor model through activation of phosphatidylinositol 3′-kinase pathway Endocrinology 141 2000 2257 2265
    • (2000) Endocrinology , vol.141 , pp. 2257-2265
    • Miyake, H.1    Nelson, C.2    Rennie, P.S.3    Gleave, M.E.4
  • 89
    • 0034749615 scopus 로고    scopus 로고
    • Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state
    • H. Murillo, H. Huang, L.J. Schmidt, D.I. Smith, and D.J. Tindall Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state Endocrinology 142 2001 4795 4805
    • (2001) Endocrinology , vol.142 , pp. 4795-4805
    • Murillo, H.1    Huang, H.2    Schmidt, L.J.3    Smith, D.I.4    Tindall, D.J.5
  • 90
    • 53549127988 scopus 로고    scopus 로고
    • CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation
    • H. Roca, Z. Varsos, and K.J. Pienta CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation J Biol Chem 283 2008 25057 25073
    • (2008) J Biol Chem , vol.283 , pp. 25057-25073
    • Roca, H.1    Varsos, Z.2    Pienta, K.J.3
  • 91
    • 53549113602 scopus 로고    scopus 로고
    • CCL2, survivin and autophagy: New links with implications in human cancer
    • H. Roca, Z.S. Varsos, K. Mizutani, and K.J. Pienta CCL2, survivin and autophagy: new links with implications in human cancer Autophagy 4 2008 969 971
    • (2008) Autophagy , vol.4 , pp. 969-971
    • Roca, H.1    Varsos, Z.S.2    Mizutani, K.3    Pienta, K.J.4
  • 92
    • 72949121254 scopus 로고    scopus 로고
    • CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cells
    • H. Roca, Z.S. Varsos, and K.J. Pienta CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cells Neoplasia 11 2009 1309 1317
    • (2009) Neoplasia , vol.11 , pp. 1309-1317
    • Roca, H.1    Varsos, Z.S.2    Pienta, K.J.3
  • 93
    • 34247468926 scopus 로고    scopus 로고
    • Chemokine networks and breast cancer metastasis
    • A.E. Karnoub, and R.A. Weinberg Chemokine networks and breast cancer metastasis Breast Dis 26 2006 75 85
    • (2006) Breast Dis , vol.26 , pp. 75-85
    • Karnoub, A.E.1    Weinberg, R.A.2
  • 94
    • 0033903714 scopus 로고    scopus 로고
    • Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer
    • T. Ueno, M. Toi, H. Saji, M. Muta, H. Bando, and K. Kuroi Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer Clin Cancer Res 6 2000 3282 3289
    • (2000) Clin Cancer Res , vol.6 , pp. 3282-3289
    • Ueno, T.1    Toi, M.2    Saji, H.3    Muta, M.4    Bando, H.5    Kuroi, K.6
  • 95
    • 0029618207 scopus 로고
    • Human MCAF gene transfer enhances the metastatic capacity of a mouse cachectic adenocarcinoma cell line in vivo
    • E. Nakashima, N. Mukaida, Y. Kubota, K. Kuno, K. Yasumoto, and F. Ichimura Human MCAF gene transfer enhances the metastatic capacity of a mouse cachectic adenocarcinoma cell line in vivo Pharm Res 12 1995 1598 1604
    • (1995) Pharm Res , vol.12 , pp. 1598-1604
    • Nakashima, E.1    Mukaida, N.2    Kubota, Y.3    Kuno, K.4    Yasumoto, K.5    Ichimura, F.6
  • 96
    • 0036329210 scopus 로고    scopus 로고
    • Correlation between vascular endothelial growth factor, angiogenesis, and tumor-associated macrophages in invasive ductal breast carcinoma
    • T. Valkovic, F. Dobrila, M. Melato, F. Sasso, C. Rizzardi, and N. Jonjic Correlation between vascular endothelial growth factor, angiogenesis, and tumor-associated macrophages in invasive ductal breast carcinoma Virchows Arch 440 2002 583 588
    • (2002) Virchows Arch , vol.440 , pp. 583-588
    • Valkovic, T.1    Dobrila, F.2    Melato, M.3    Sasso, F.4    Rizzardi, C.5    Jonjic, N.6
  • 97
    • 34547184682 scopus 로고    scopus 로고
    • CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration
    • R.D. Loberg, C. Ying, M. Craig, L. Yan, L.A. Snyder, and K.J. Pienta CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration Neoplasia 9 2007 556 562
    • (2007) Neoplasia , vol.9 , pp. 556-562
    • Loberg, R.D.1    Ying, C.2    Craig, M.3    Yan, L.4    Snyder, L.A.5    Pienta, K.J.6
  • 98
    • 4644261592 scopus 로고    scopus 로고
    • Mechanisms of bone metastasis
    • G.D. Roodman Mechanisms of bone metastasis N Engl J Med 350 2004 1655 1664
    • (2004) N Engl J Med , vol.350 , pp. 1655-1664
    • Roodman, G.D.1
  • 99
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • G.R. Mundy Metastasis to bone: causes, consequences and therapeutic opportunities Nat Rev Cancer 2 2002 584 593
    • (2002) Nat Rev Cancer , vol.2 , pp. 584-593
    • Mundy, G.R.1
  • 100
    • 34848896887 scopus 로고    scopus 로고
    • The evolving biology and treatment of prostate cancer
    • R.S. Taichman, R.D. Loberg, R. Mehra, and K.J. Pienta The evolving biology and treatment of prostate cancer J Clin Invest 117 2007 2351 2361
    • (2007) J Clin Invest , vol.117 , pp. 2351-2361
    • Taichman, R.S.1    Loberg, R.D.2    Mehra, R.3    Pienta, K.J.4
  • 102
    • 34547689484 scopus 로고    scopus 로고
    • Organotropism of breast cancer metastasis
    • X. Lu, and Y. Kang Organotropism of breast cancer metastasis J Mammary Gland Biol Neoplasia 12 2007 153 162
    • (2007) J Mammary Gland Biol Neoplasia , vol.12 , pp. 153-162
    • Lu, X.1    Kang, Y.2
  • 104
    • 34447264104 scopus 로고    scopus 로고
    • The role of tumor microenvironment in prostate cancer bone metastasis
    • C. Morrissey, and R.L. Vessella The role of tumor microenvironment in prostate cancer bone metastasis J Cell Biochem 101 2007 873 886
    • (2007) J Cell Biochem , vol.101 , pp. 873-886
    • Morrissey, C.1    Vessella, R.L.2
  • 105
    • 0036186907 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 (MCP-1), secreted by bone marrow endothelial cells, induces chemoattraction of 5T multiple myeloma cells
    • K. Vanderkerken, I. Vande Broek, D.L. Eizirik, E. Van Valckenborgh, K. Asosingh, and I. Van Riet Monocyte chemoattractant protein-1 (MCP-1), secreted by bone marrow endothelial cells, induces chemoattraction of 5T multiple myeloma cells Clin Exp Metastasis 19 2002 87 90
    • (2002) Clin Exp Metastasis , vol.19 , pp. 87-90
    • Vanderkerken, K.1    Vande Broek, I.2    Eizirik, D.L.3    Van Valckenborgh, E.4    Asosingh, K.5    Van Riet, I.6
  • 106
    • 0037464332 scopus 로고    scopus 로고
    • Chemokine receptor CCR2 is expressed by human multiple myeloma cells and mediates migration to bone marrow stromal cell-produced monocyte chemotactic proteins MCP-1, -2 and -3
    • I. Vande Broek, K. Asosingh, K. Vanderkerken, N. Straetmans, B. Van Camp, and I. Van Riet Chemokine receptor CCR2 is expressed by human multiple myeloma cells and mediates migration to bone marrow stromal cell-produced monocyte chemotactic proteins MCP-1, -2 and -3 Br J Cancer 88 2003 855 862
    • (2003) Br J Cancer , vol.88 , pp. 855-862
    • Vande Broek, I.1    Asosingh, K.2    Vanderkerken, K.3    Straetmans, N.4    Van Camp, B.5    Van Riet, I.6
  • 107
    • 69949092197 scopus 로고    scopus 로고
    • Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis
    • H. Hu, L. Sun, C. Guo, Q. Liu, Z. Zhou, and L. Peng Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis Clin Cancer Res 15 2009 5485 5493
    • (2009) Clin Cancer Res , vol.15 , pp. 5485-5493
    • Hu, H.1    Sun, L.2    Guo, C.3    Liu, Q.4    Zhou, Z.5    Peng, L.6
  • 108
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • L.M. Coussens, and Z. Werb Inflammation and cancer Nature 420 2002 860 867
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 109
    • 0037444031 scopus 로고    scopus 로고
    • Pathological and molecular aspects of prostate cancer
    • A.M. DeMarzo, W.G. Nelson, W.B. Isaacs, and J.I. Epstein Pathological and molecular aspects of prostate cancer Lancet 361 2003 955 964
    • (2003) Lancet , vol.361 , pp. 955-964
    • Demarzo, A.M.1    Nelson, W.G.2    Isaacs, W.B.3    Epstein, J.I.4
  • 110
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • A. Sica, T. Schioppa, A. Mantovani, and P. Allavena Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy Eur J Cancer 42 2006 717 727
    • (2006) Eur J Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 112
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • F. Balkwill, K.A. Charles, and A. Mantovani Smoldering and polarized inflammation in the initiation and promotion of malignant disease Cancer Cell 7 2005 211 217
    • (2005) Cancer Cell , vol.7 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 113
    • 40049088602 scopus 로고    scopus 로고
    • The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages
    • P. Allavena, A. Sica, G. Solinas, C. Porta, and A. Mantovani The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages Crit Rev Oncol Hematol 66 2008 1 9
    • (2008) Crit Rev Oncol Hematol , vol.66 , pp. 1-9
    • Allavena, P.1    Sica, A.2    Solinas, G.3    Porta, C.4    Mantovani, A.5
  • 114
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • C. Murdoch, M. Muthana, S.B. Coffelt, and C.E. Lewis The role of myeloid cells in the promotion of tumour angiogenesis Nat Rev Cancer 8 2008 618 631
    • (2008) Nat Rev Cancer , vol.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 115
    • 76549119724 scopus 로고    scopus 로고
    • La mala educacion of tumor-associated macrophages: Diverse pathways and new players
    • A. Mantovani La mala educacion of tumor-associated macrophages: diverse pathways and new players Cancer Cell 17 2010 111 112
    • (2010) Cancer Cell , vol.17 , pp. 111-112
    • Mantovani, A.1
  • 116
    • 70350728931 scopus 로고    scopus 로고
    • Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation
    • G. Solinas, G. Germano, A. Mantovani, and P. Allavena Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation J Leukoc Biol 86 2009 1065 1073
    • (2009) J Leukoc Biol , vol.86 , pp. 1065-1073
    • Solinas, G.1    Germano, G.2    Mantovani, A.3    Allavena, P.4
  • 117
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • F. Balkwill, and A. Mantovani Inflammation and cancer: back to Virchow? Lancet 357 2001 539 545
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 118
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • L. Bingle, N.J. Brown, and C.E. Lewis The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies J Pathol 196 2002 254 265
    • (2002) J Pathol , vol.196 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 120
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • A. Mantovani, S. Sozzani, M. Locati, P. Allavena, and A. Sica Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes Trends Immunol 23 2002 549 555
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 121
    • 0027965621 scopus 로고
    • Tumor-associated macrophages in neoplastic progression: A paradigm for the in vivo function of chemokines
    • A. Mantovani Tumor-associated macrophages in neoplastic progression: a paradigm for the in vivo function of chemokines Lab Invest 71 1994 5 16
    • (1994) Lab Invest , vol.71 , pp. 5-16
    • Mantovani, A.1
  • 122
    • 71749088821 scopus 로고    scopus 로고
    • CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization
    • H. Roca, Z.S. Varsos, S. Sud, M.J. Craig, C. Ying, and K.J. Pienta CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization J Biol Chem 284 2009 34342 34354
    • (2009) J Biol Chem , vol.284 , pp. 34342-34354
    • Roca, H.1    Varsos, Z.S.2    Sud, S.3    Craig, M.J.4    Ying, C.5    Pienta, K.J.6
  • 123
  • 124
    • 68549083509 scopus 로고    scopus 로고
    • Possible mechanism of CCL2-induced Akt activation in prostate cancer cells
    • K. Mizutani, H. Roca, Z. Varsos, and K.J. Pienta Possible mechanism of CCL2-induced Akt activation in prostate cancer cells Anticancer Res 29 2009 3109 3113
    • (2009) Anticancer Res , vol.29 , pp. 3109-3113
    • Mizutani, K.1    Roca, H.2    Varsos, Z.3    Pienta, K.J.4
  • 125
    • 70350381008 scopus 로고    scopus 로고
    • Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone
    • X. Lu, and Y. Kang Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone J Biol Chem 284 2009 29087 29096
    • (2009) J Biol Chem , vol.284 , pp. 29087-29096
    • Lu, X.1    Kang, Y.2
  • 126
    • 41649116240 scopus 로고    scopus 로고
    • Plasticity in tumor-promoting inflammation: Impairment of macrophage recruitment evokes a compensatory neutrophil response
    • J.C. Pahler, S. Tazzyman, N. Erez, Y.Y. Chen, C. Murdoch, and H. Nozawa Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response Neoplasia 10 2008 329 340
    • (2008) Neoplasia , vol.10 , pp. 329-340
    • Pahler, J.C.1    Tazzyman, S.2    Erez, N.3    Chen, Y.Y.4    Murdoch, C.5    Nozawa, H.6
  • 127
    • 34250758650 scopus 로고    scopus 로고
    • Induction of an antitumoral immune response by wild-type adeno-associated virus type 2 in an in vivo model of pancreatic carcinoma
    • S. Eisold, J. Schmidt, E. Ryschich, M. Gock, E. Klar, and M. von Knebel Doeberitz Induction of an antitumoral immune response by wild-type adeno-associated virus type 2 in an in vivo model of pancreatic carcinoma Pancreas 35 2007 63 72
    • (2007) Pancreas , vol.35 , pp. 63-72
    • Eisold, S.1    Schmidt, J.2    Ryschich, E.3    Gock, M.4    Klar, E.5    Von Knebel Doeberitz, M.6
  • 128
    • 76149146398 scopus 로고    scopus 로고
    • IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
    • V. Gocheva, H.W. Wang, B.B. Gadea, T. Shree, K.E. Hunter, and A.L. Garfall IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion Genes Dev 24 2010 241 255
    • (2010) Genes Dev , vol.24 , pp. 241-255
    • Gocheva, V.1    Wang, H.W.2    Gadea, B.B.3    Shree, T.4    Hunter, K.E.5    Garfall, A.L.6
  • 129
    • 38849171267 scopus 로고    scopus 로고
    • Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis
    • B.K. Popivanova, K. Kitamura, Y. Wu, T. Kondo, T. Kagaya, and S. Kaneko Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis J Clin Invest 118 2008 560 570
    • (2008) J Clin Invest , vol.118 , pp. 560-570
    • Popivanova, B.K.1    Kitamura, K.2    Wu, Y.3    Kondo, T.4    Kagaya, T.5    Kaneko, S.6
  • 130
    • 0035158575 scopus 로고    scopus 로고
    • Inflammatory chemokine transport and presentation in HEV: A remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues
    • R.T. Palframan, S. Jung, G. Cheng, W. Weninger, Y. Luo, and M. Dorf Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues J Exp Med 194 2001 1361 1373
    • (2001) J Exp Med , vol.194 , pp. 1361-1373
    • Palframan, R.T.1    Jung, S.2    Cheng, G.3    Weninger, W.4    Luo, Y.5    Dorf, M.6
  • 131
    • 0030062875 scopus 로고    scopus 로고
    • Regulation and expression of chemokines: Potential role in glomerulonephritis
    • Z. Brown, R.L. Robson, and J. Westwick Regulation and expression of chemokines: potential role in glomerulonephritis J Leukoc Biol 59 1996 75 80
    • (1996) J Leukoc Biol , vol.59 , pp. 75-80
    • Brown, Z.1    Robson, R.L.2    Westwick, J.3
  • 132
  • 133
    • 0025333516 scopus 로고
    • Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line
    • C.O. Zachariae, A.O. Anderson, H.L. Thompson, E. Appella, A. Mantovani, and J.J. Oppenheim Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line J Exp Med 171 1990 2177 2182
    • (1990) J Exp Med , vol.171 , pp. 2177-2182
    • Zachariae, C.O.1    Anderson, A.O.2    Thompson, H.L.3    Appella, E.4    Mantovani, A.5    Oppenheim, J.J.6
  • 134
    • 33847208844 scopus 로고    scopus 로고
    • Bone metastasis: Can osteoclasts be excluded?
    • T.J. Martin, and G.R. Mundy Bone metastasis: can osteoclasts be excluded? Nature 445 2007 E19 [Discussion E-20]
    • (2007) Nature , vol.445 , pp. 19
    • Martin, T.J.1    Mundy, G.R.2
  • 135
    • 9644284522 scopus 로고    scopus 로고
    • The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation
    • T.R. Kyriakides, M.J. Foster, G.E. Keeney, A. Tsai, C.M. Giachelli, and I. Clark-Lewis The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation Am J Pathol 165 2004 2157 2166
    • (2004) Am J Pathol , vol.165 , pp. 2157-2166
    • Kyriakides, T.R.1    Foster, M.J.2    Keeney, G.E.3    Tsai, A.4    Giachelli, C.M.5    Clark-Lewis, I.6
  • 137
    • 33645820419 scopus 로고    scopus 로고
    • Circulating osteoprotegerin and soluble RANKL: Do they have a future in clinical practice?
    • A. Dovio, V. Data, and A. Angeli Circulating osteoprotegerin and soluble RANKL: do they have a future in clinical practice? J Endocrinol Invest 28 2005 14 22
    • (2005) J Endocrinol Invest , vol.28 , pp. 14-22
    • Dovio, A.1    Data, V.2    Angeli, A.3
  • 138
    • 34248545487 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-1 mediates prostate cancer-induced bone resorption
    • Y. Lu, Z. Cai, G. Xiao, E.T. Keller, A. Mizokami, and Z. Yao Monocyte chemotactic protein-1 mediates prostate cancer-induced bone resorption Cancer Res 67 2007 3646 3653
    • (2007) Cancer Res , vol.67 , pp. 3646-3653
    • Lu, Y.1    Cai, Z.2    Xiao, G.3    Keller, E.T.4    Mizokami, A.5    Yao, Z.6
  • 139
    • 62649173106 scopus 로고    scopus 로고
    • Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts
    • K. Mizutani, S. Sud, and K.J. Pienta Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts J Cell Biochem 106 2009 563 569
    • (2009) J Cell Biochem , vol.106 , pp. 563-569
    • Mizutani, K.1    Sud, S.2    Pienta, K.J.3
  • 140
    • 70350705942 scopus 로고    scopus 로고
    • The chemokine CCL2 increases prostate tumor growth and bone metastasis through macrophage and osteoclast recruitment
    • K. Mizutani, S. Sud, N.A. McGregor, G. Martinovski, B.T. Rice, and M.J. Craig The chemokine CCL2 increases prostate tumor growth and bone metastasis through macrophage and osteoclast recruitment Neoplasia 11 2009 1235 1242
    • (2009) Neoplasia , vol.11 , pp. 1235-1242
    • Mizutani, K.1    Sud, S.2    McGregor, N.A.3    Martinovski, G.4    Rice, B.T.5    Craig, M.J.6
  • 141
    • 62549155841 scopus 로고    scopus 로고
    • Monocyte chemotactic protein 1 promotes lung cancer-induced bone resorptive lesions in vivo
    • Z. Cai, Q. Chen, J. Chen, Y. Lu, G. Xiao, and Z. Wu Monocyte chemotactic protein 1 promotes lung cancer-induced bone resorptive lesions in vivo Neoplasia 11 2009 228 236
    • (2009) Neoplasia , vol.11 , pp. 228-236
    • Cai, Z.1    Chen, Q.2    Chen, J.3    Lu, Y.4    Xiao, G.5    Wu, Z.6
  • 142
    • 77549086214 scopus 로고    scopus 로고
    • CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis
    • J. Zhang, L. Patel, and K.J. Pienta CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis Cytokine Growth Factor Rev 21 2009 41 48
    • (2009) Cytokine Growth Factor Rev , vol.21 , pp. 41-48
    • Zhang, J.1    Patel, L.2    Pienta, K.J.3
  • 143
    • 28844443794 scopus 로고    scopus 로고
    • Attenuated liver tumor formation in the absence of CCR2 with a concomitant reduction in the accumulation of hepatic stellate cells, macrophages and neovascularization
    • X. Yang, P. Lu, Y. Ishida, W.A. Kuziel, C. Fujii, and N. Mukaida Attenuated liver tumor formation in the absence of CCR2 with a concomitant reduction in the accumulation of hepatic stellate cells, macrophages and neovascularization Int J Cancer 118 2006 335 345
    • (2006) Int J Cancer , vol.118 , pp. 335-345
    • Yang, X.1    Lu, P.2    Ishida, Y.3    Kuziel, W.A.4    Fujii, C.5    Mukaida, N.6
  • 144
    • 61349113394 scopus 로고    scopus 로고
    • Extratumoral macrophages promote tumor and vascular growth in an orthotopic rat prostate tumor model
    • S. Halin, S.H. Rudolfsson, N. Van Rooijen, and A. Bergh Extratumoral macrophages promote tumor and vascular growth in an orthotopic rat prostate tumor model Neoplasia 11 2009 177 186
    • (2009) Neoplasia , vol.11 , pp. 177-186
    • Halin, S.1    Rudolfsson, S.H.2    Van Rooijen, N.3    Bergh, A.4
  • 145
    • 34447556692 scopus 로고    scopus 로고
    • Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft
    • S. Gazzaniga, A.I. Bravo, A. Guglielmotti, N. van Rooijen, F. Maschi, and A. Vecchi Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft J Invest Dermatol 127 2007 2031 2041
    • (2007) J Invest Dermatol , vol.127 , pp. 2031-2041
    • Gazzaniga, S.1    Bravo, A.I.2    Guglielmotti, A.3    Van Rooijen, N.4    Maschi, F.5    Vecchi, A.6
  • 146
    • 33746926292 scopus 로고    scopus 로고
    • Clodronate-liposome-mediated depletion of tumour-associated macrophages: A new and highly effective antiangiogenic therapy approach
    • S.M. Zeisberger, B. Odermatt, C. Marty, A.H. Zehnder-Fjallman, K. Ballmer-Hofer, and R.A. Schwendener Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach Br J Cancer 95 2006 272 281
    • (2006) Br J Cancer , vol.95 , pp. 272-281
    • Zeisberger, S.M.1    Odermatt, B.2    Marty, C.3    Zehnder-Fjallman, A.H.4    Ballmer-Hofer, K.5    Schwendener, R.A.6
  • 147
    • 35548950622 scopus 로고    scopus 로고
    • Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis
    • Y.N. Kimura, K. Watari, A. Fotovati, F. Hosoi, K. Yasumoto, and H. Izumi Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis Cancer Sci 98 2007 2009 2018
    • (2007) Cancer Sci , vol.98 , pp. 2009-2018
    • Kimura, Y.N.1    Watari, K.2    Fotovati, A.3    Hosoi, F.4    Yasumoto, K.5    Izumi, H.6
  • 149
    • 71849118970 scopus 로고    scopus 로고
    • Chemokine CCL2/MCP-1 negatively regulates metastasis in a highly bone marrow-metastatic mouse breast cancer model
    • M. Takahashi, H. Miyazaki, M. Furihata, H. Sakai, T. Konakahara, and M. Watanabe Chemokine CCL2/MCP-1 negatively regulates metastasis in a highly bone marrow-metastatic mouse breast cancer model Clin Exp Metastasis 26 2009 817 828
    • (2009) Clin Exp Metastasis , vol.26 , pp. 817-828
    • Takahashi, M.1    Miyazaki, H.2    Furihata, M.3    Sakai, H.4    Konakahara, T.5    Watanabe, M.6
  • 150
    • 0028113476 scopus 로고
    • Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells
    • S. Huang, R.K. Singh, K. Xie, M. Gutman, K.K. Berry, and C.D. Bucana Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells Cancer Immunol Immunother 39 1994 231 238
    • (1994) Cancer Immunol Immunother , vol.39 , pp. 231-238
    • Huang, S.1    Singh, R.K.2    Xie, K.3    Gutman, M.4    Berry, K.K.5    Bucana, C.D.6
  • 151
    • 0029155671 scopus 로고
    • Suppression of tumor growth and metastasis of murine renal adenocarcinoma by syngeneic fibroblasts genetically engineered to secrete the JE/MCP-1 cytokine
    • S. Huang, K. Xie, R.K. Singh, M. Gutman, and M. Bar-Eli Suppression of tumor growth and metastasis of murine renal adenocarcinoma by syngeneic fibroblasts genetically engineered to secrete the JE/MCP-1 cytokine J Interferon Cytokine Res 15 1995 655 665
    • (1995) J Interferon Cytokine Res , vol.15 , pp. 655-665
    • Huang, S.1    Xie, K.2    Singh, R.K.3    Gutman, M.4    Bar-Eli, M.5
  • 152
    • 0031570009 scopus 로고    scopus 로고
    • Antibody to Mac-1 or monocyte chemoattractant protein-1 inhibits monocyte recruitment and promotes tumor growth
    • L. Zhang, T. Yoshimura, and D.T. Graves Antibody to Mac-1 or monocyte chemoattractant protein-1 inhibits monocyte recruitment and promotes tumor growth J Immunol 158 1997 4855 4861
    • (1997) J Immunol , vol.158 , pp. 4855-4861
    • Zhang, L.1    Yoshimura, T.2    Graves, D.T.3
  • 153
    • 10744234018 scopus 로고    scopus 로고
    • The CC chemokine MCP-1/CCL2 in pancreatic cancer progression: Regulation of expression and potential mechanisms of antimalignant activity
    • P. Monti, B.E. Leone, F. Marchesi, G. Balzano, A. Zerbi, and F. Scaltrini The CC chemokine MCP-1/CCL2 in pancreatic cancer progression: regulation of expression and potential mechanisms of antimalignant activity Cancer Res 63 2003 7451 7461
    • (2003) Cancer Res , vol.63 , pp. 7451-7461
    • Monti, P.1    Leone, B.E.2    Marchesi, F.3    Balzano, G.4    Zerbi, A.5    Scaltrini, F.6
  • 154
    • 0029103127 scopus 로고
    • Chemokine gene transfection into tumour cells reduced tumorigenicity in nude mice in association with neutrophilic infiltration
    • K. Hirose, M. Hakozaki, Y. Nyunoya, Y. Kobayashi, K. Matsushita, and T. Takenouchi Chemokine gene transfection into tumour cells reduced tumorigenicity in nude mice in association with neutrophilic infiltration Br J Cancer 72 1995 708 714
    • (1995) Br J Cancer , vol.72 , pp. 708-714
    • Hirose, K.1    Hakozaki, M.2    Nyunoya, Y.3    Kobayashi, Y.4    Matsushita, K.5    Takenouchi, T.6
  • 155
    • 0035336409 scopus 로고    scopus 로고
    • Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells
    • M. Nesbit, H. Schaider, T.H. Miller, and M. Herlyn Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells J Immunol 166 2001 6483 6490
    • (2001) J Immunol , vol.166 , pp. 6483-6490
    • Nesbit, M.1    Schaider, H.2    Miller, T.H.3    Herlyn, M.4


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