Organotropism of breast cancer metastasis

Journal of Mammary Gland Biology and Neoplasia

Volumn 12, Issue 2-3, 2007, Pages 153-162

  Lu, Xin ^a   Kang, Yibin ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

Bone metastasis; Breast cancer; Cancer stem cell; Lung metastasis; Metastasis; Metastasis niche; Organotropism; Tissue specific metastasis

Indexed keywords

OSTEOCLAST DIFFERENTIATION FACTOR;

ARTICLE; BONE METASTASIS; BRAIN METASTASIS; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CANCER MORTALITY; CANCER STEM CELL; CLINICAL EFFECTIVENESS; CONCEPTUAL FRAMEWORK; FUNCTIONAL GENOMICS; HUMAN; IN VIVO STUDY; LIVER METASTASIS; LUNG METASTASIS; METASTASIS; MICROENVIRONMENT; MOLECULAR BIOLOGY; NONHUMAN; ORGANOTROPH; TARGET ORGAN; TISSUE SPECIFICITY; VASCULAR ENDOTHELIUM;

ANIMALS; BONE NEOPLASMS; BREAST NEOPLASMS; HUMANS; LUNG NEOPLASMS; NEOPLASM METASTASIS; NEOPLASTIC STEM CELLS; RANK LIGAND;

EID: 34547689484     PISSN: 10833021     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10911-007-9047-3     Document Type: Article

References (68)

1. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, et al. Cancer statistics, 2005. CA Cancer J Clin 2005;55 1:10-30.
2. Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002;2 8:563-72.
3. Gupta GP, Massague J. Cancer metastasis: Building a framework. Cell 2006;127 4:679-95.
4. Steeg PS. Tumor metastasis: Mechanistic insights and clinical challenges. Nat Med 2006;12 8:895-904.
5. Hess KR, Varadhachary GR, Taylor SH, Wei W, Raber MN, Lenzi R, et al. Metastatic patterns in adenocarcinoma. Cancer 2006;106 7:1624-33.
6. Lee Y-T. Breast carcinoma: Pattern of metastasis at autopsy. J Surg Oncol 1983;23 3:175-80.
7. Weil RJ, Palmieri DC, Bronder JL, Stark AM, Steeg PS. Breast cancer metastasis to the central nervous system. Am J Pathol 2005;167 4:913-20.
8. Fidler IJ. Selection of successive tumour lines for metastasis. Nat New Biol 1973;242 118:148-9.
9. Kang Y. Functional genomic analysis of cancer metastasis: Biologic insights and clinical implications. Expert Rev Mol Diagn 2005;5 3:385-95.
10. Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003;3 6:537-49.
11. Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005;436 7050:518-24.
12. Minn AJ, Kang Y, Serganova I, Gupta GP, Giri DD, Doubrovin M, et al. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J Clin Invest 2005;115 1:44-55.
13. Paget S. Distribution of secondary growths in cancer of the breast. Lancet 1889;1:571-3.
14. Fidler IJ. The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003;3 6:453-8.
15. Welch DR. Technical considerations for studying cancer metastasis in vivo. Clin Exp Metastasis 1997;15 3:272-306.
16. Kang Y, He W, Tulley S, Gupta GP, Serganova I, Chen CR, et al. Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. Proc Natl Acad Sci USA 2005;102 39:13909-14.
17. Mundy GR. Metastasis to bone: Causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002;2 8:584-93.
18. Harada S, Rodan GA. Control of osteoblast function and regulation of bone mass. Nature 2003;423 6937:349-55.
19. Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature 2003;423 6937:337-42.
20. Siclari VA, Guise TA, Chirgwin JM. Molecular interactions between breast cancer cells and the bone microenvironment drive skeletal metastases. Cancer Metastasis Rev 2006;25 4:621-33.
21. Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004;350 16:1655-64.
22. Pantschenko AG, Pushkar I, Anderson KH, Wang Y, Miller LJ, Kurtzman SH, et al. The interleukin-1 family of cytokines and receptors in human breast cancer: Implications for tumor progression. Int J Oncol 2003;23 2:269-84.
23. Bendre MS, Gaddy-Kurten D, Mon-Foote T, Akel NS, Skinner RA, Nicholas RW, et al. Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo. Cancer Res 2002;62 19:5571-9.
24. Park BK, Zhang H, Zeng Q, Dai J, Keller ET, Giordano T, et al. NF-[kappa]B in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF. Nat Med 2007;13 1:62-9
25. Ohshiba T, Miyaura C, Ito A. Role of prostaglandin E produced by osteoblasts in osteolysis due to bone metastasis. Biochem Biophys Res Commun 2003;300 4:957-64.
26. Gupta GP, Massague J. Cancer Metastasis: Building a Framework. Cell 2006;127 4:679-95.
27. Kovacs CS. Calcium and Bone Metabolism During Pregnancy and Lactation. J Mammary Gland Biol Neoplasia 2005;10 2:105-18.
28. VanHouten JN, Dann P, Stewart AF, Watson CJ, Pollak M, Karaplis AC, et al. Mammary-specific deletion of parathyroid hormone-related protein preserves bone mass during lactation. J Clin Invest 2003;112 9:1429-36.
29. Fata JE, Kong YY, Li J, Sasaki T, Irie-Sasaki J, Moorehead RA, et al. The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. Cell 2000;103 1:41-50.
30. Cao Y, Bonizzi G, Seagroves TN, Greten FR, Johnson R, Schmidt EV, et al. IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. Cell 2001;107 6:763-75.
31. Jones DH, Nakashima T, Sanchez OH, Kozieradzki I, Komarova SV, Sarosi I, et al. Regulation of cancer cell migration and bone metastasis by RANKL. Nature 2006;440 7084:692-6.
32. Shore P. A role for Runx2 in normal mammary gland and breast cancer bone metastasis. J Cell Biochem 2005;96 3:484-9.
33. Barnes GL, Javed A, Waller SM, Kamal MH, Hebert KE, Hassan MQ, et al. Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res 2003;63 10:2631-7.
34. Pratap J, Javed A, Languino LR, van Wijnen AJ, Stein JL, Stein GS, et al. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol 2005;25 19:8581-91.
35. Barnes GL, Hebert KE, Kamal M, Javed A, Einhorn TA, Lian JB, et al. Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease. Cancer Res 2004;64 13:4506-13.
36. Bellahcene A, Bachelier R, Detry C, Lidereau R, Clezardin P, Castronovo V. Transcriptome analysis reveals an osteoblast-like phenotype for human osteotropic breast cancer cells. Breast Cancer Res Treat 2007;101 2:135-48.
37. Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001;410 6824:50-6.
38. Brown DM, Ruoslahti E. Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell 2004;5 4:365-74.
39. Abdel-Ghany M, Cheng H-C, Elble RC, Pauli BU. The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis. J Biol Chem 2001;276 27:25438-46.
40. Cheng H-C, Abdel-Ghany M, Elble RC, Pauli BU. Lung endothelial ipeptidyl peptidaseD IV promotes adhesion and metastasis of rat breast cancer cells via tumor cell surface-associated fibronectin. J Biol Chem 1998;273 37:24207-15.
41. Jiang WG, Matsumoto K, Nakamura T, ebrary Inc. Growth factors and their receptors in cancer metastasis. Dordrecht: Kluwer; 2001.
42. Muraoka RS, Dumont N, Ritter CA, Dugger TC, Brantley DM, Chen J, et al. Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest 2002;109 12:1551-9.
43. Siegel PM, Shu W, Cardiff RD, Muller WJ, Massague J. Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis. Proc Natl Acad Sci USA 2003;100 14:8430-5.
44. Kang Y. Pro-metastasis function of TGF beta mediated by the smad pathway. J Cell Biochem 2006;98 6:1380-90.
45. Yingling JM, Blanchard KL, Sawyer JS. Development of TGFb signalling inhibitors for cancer therapy. Nat Rev Drug Discov 2004;3 12:1011-22.
46. Sierra A, Price JE, Garcia-Ramirez M, Mendez O, Lopez L, Fabra A. Astrocyte-derived cytokines contribute to the metastatic brain specificity of breast cancer cells. Lab Invest 1997;77 4:357-68.
47. Kim LS, Huang S, Lu W, Lev DC, Price JE. Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice. Clin Exp Metastasis 2004;21 2:107-18.
48. Stessels F, Van den Eynden G, Van der Auwera I, Salgado R, Van den Heuvel E, Harris AL, et al. Breast adenocarcinoma liver metastases, in contrast to colorectal cancer liver metastases, display a non-angiogenic growth pattern that preserves the stroma and lacks hypoxia. Br J Cancer 2004;90 7:1429-36.
49. O'Reilly SM, Richards MA, Rubens RD. Liver metastases from breast cancer: The relationship between clinical, biochemical and pathological features and survival. Eur J Cancer 1990;26 5:574-7.
50. Yoneda T, Williams PJ, Hiraga T, Niewolna M, Nishimura R. A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro. J Bone Miner Res 2001;16 8:1486-95.
51. Price JE. Metastasis from human breast cancer cell lines. Breast Cancer Res Treat 1996;39 1:93-102.
52. Aslakson CJ, Miller FR. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res 1992;52 6:1399-405.
53. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. From the cover: Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003;100 7:3983-88.
54. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003;63 18:5821-28.
55. Hemmati HD, Nakano I, Lazareff JA, Masterman-Smith M, Geschwind DH, Bronner-Fraser M, et al. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA 2003;100 25:15178-83.
56. Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, et al. Identification of human brain tumour initiating cells. Nature 2004;432 7015:396-401.
57. O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007;445 7123:106-10.
58. Polyak K, Hahn WC. Roots and stems: Stem cells in cancer. 2006;12 3:296-300.
59. Jordan CT, Guzman ML, Noble M. Cancer stem cells. N Engl J Med 2006;355 12:1253-61.
60. Li F, Tiede B, Massague J, Kang Y. Beyond tumorigenesis: Cancer stem cells in metastasis. Cell Res 2007;17 1:3-14.
61. Shackleton M, Vaillant F, Simpson KJ, Stingl J, Smyth GK, Asselin-Labat ML, et al. Generation of a functional mammary gland from a single stem cell. Nature 2006;439 7072:84-8.
62. Talmadge JE, Wolman SR, Fidler IJ. Evidence for the clonal origin of spontaneous metastases. Science 1982;217 4557:361-3.
63. Fidler IJ, Talmadge JE. Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell. Cancer Res 1986;46 10:5167-71.
64. Weigelt B, Peterse JL, van't Veer LJ. Breast cancer metastasis: Markers and models. Nat Rev Cancer 2005;5 8:591-602.
65. Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005;438 7069:820-7.
66. Kaplan RN, Rafii S, Lyden D. Preparing the "soil": The premetastatic niche. Cancer Res 2006;66 23:11089-93.
67. Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003;425 6960:841-6.
68. Zhang J, Niu C, Ye L, Huang H, He X, Tong WG, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003;425 6960:836-41.