-
1
-
-
0032695278
-
Arbiter of differentiation and death: Notchsignaling meets apoptosis
-
Miele, L.; Osborne, B. Arbiter of differentiation and death: Notchsignaling meets apoptosis. J. Cell, Physiol., 1999, 181, 393-409.
-
(1999)
J. Cell, Physiol.
, vol.181
, pp. 393-409
-
-
Miele, L.1
Osborne, B.2
-
2
-
-
33644752839
-
Notch signaling
-
Miele, L. Notch signaling. Clin. Cancer Res., 2006, 12, 1074-1079.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 1074-1079
-
-
Miele, L.1
-
3
-
-
0030748716
-
The ins and outs of notch signaling
-
Weinmaster, G. The ins and outs of notch signaling. Mol. Cell, Neurosci., 1997, 9, 91-102.
-
(1997)
Mol. Cell, Neurosci.
, vol.9
, pp. 91-102
-
-
Weinmaster, G.1
-
4
-
-
64249172203
-
The canonical Notch signaling pathway:Unfolding the activation mechanism
-
Kopan, R.; Ilagan, M. X. The canonical Notch signaling pathway:unfolding the activation mechanism. Cell, 2009, 137, 216-233.
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
5
-
-
65549121943
-
Notch signaling: The core pathway and its posttranslationalregulation
-
Fortini, M. E. Notch signaling: the core pathway and its posttranslationalregulation. Dev. Cell, 2009, 16, 633-647.
-
(2009)
Dev. Cell
, vol.16
, pp. 633-647
-
-
Fortini, M.E.1
-
6
-
-
33745509199
-
Notch signaling as a novelcancer therapeutic target
-
Miele, L.; Miao, H.; Nickoloff, B. J. Notch signaling as a novelcancer therapeutic target. Curr. Cancer Drug Targets, 2006, 6,313-323.
-
(2006)
Curr. Cancer Drug Targets
, vol.6
, pp. 313-323
-
-
Miele, L.1
Miao, H.2
Nickoloff, B.J.3
-
7
-
-
50849111710
-
Rational targeting of Notch signaling in cancer
-
Rizzo, P.; Osipo, C.; Foreman, K.; Golde, T.; Osborne, B.; Miele, L. Rational targeting of Notch signaling in cancer. Oncogene, 2008, 27, 5124-5131.
-
(2008)
Oncogene
, vol.27
, pp. 5124-5131
-
-
Rizzo, P.1
Osipo, C.2
Foreman, K.3
Golde, T.4
Osborne, B.5
Miele, L.6
-
8
-
-
58149174376
-
Exploitation of theNotch signaling pathway as a novel target for cancer therapy
-
Wang, Z.; Li, Y.; Banerjee, S.; Sarkar, F. H. Exploitation of theNotch signaling pathway as a novel target for cancer therapy. Anti-Cancer Res., 2008, 28, 3621-3630.
-
(2008)
Anti-Cancer Res.
, vol.28
, pp. 3621-3630
-
-
Wang, Z.1
Li, Y.2
Banerjee, S.3
Sarkar, F.H.4
-
9
-
-
50849104230
-
Notch tumor suppressor function
-
Dotto, G. P. Notch tumor suppressor function. Oncogene, 2008, 27, 5115-5123.
-
(2008)
Oncogene
, vol.27
, pp. 5115-5123
-
-
Dotto, G.P.1
-
10
-
-
67650874081
-
Cancerstatistics
-
Jemal, A.; Siegel, R.; Ward, E.; Hao, Y.; Xu, J.; Thun, M. J. Cancerstatistics. CA Cancer J. Clin., 2009, 59, 225-249.
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
11
-
-
28244469644
-
The Notch signaling pathway is related to neurovascularprogression of pancreatic cancer
-
Buchler, P.; Gazdhar, A.; Schubert, M.; Giese, N.; Reber, H. A.; Hines, O. J.; Giese, T.; Ceyhan, G. O.; Muller, M.; Buchler, M. W.; Friess, H. The Notch signaling pathway is related to neurovascularprogression of pancreatic cancer. Ann. Surg., 2005, 242, 791-800.
-
(2005)
Ann. Surg.
, vol.242
, pp. 791-800
-
-
Buchler, P.1
Gazdhar, A.2
Schubert, M.3
Giese, N.4
Reber, H.A.5
Hines, O.J.6
Giese, T.7
Ceyhan, G.O.8
Muller, M.9
Buchler, M.W.10
Friess, H.11
-
12
-
-
10744223624
-
Notch mediates TGF alpha-induced changes in epithelialdifferentiation during pancreatic tumorigenesis
-
Miyamoto, Y.; Maitra, A.; Ghosh, B.; Zechner, U.; Argani, P.; Iacobuzio-Donahue, C. A.; Sriuranpong, V.; Iso, T.; Meszoely, I. M.; Wolfe, M. S.; Hruban, R. H.; Ball, D. W.; Schmid, R. M.; Leach, S. D. Notch mediates TGF alpha-induced changes in epithelialdifferentiation during pancreatic tumorigenesis. Cancer Cell, 2003, 3, 565-576.
-
(2003)
Cancer Cell
, vol.3
, pp. 565-576
-
-
Miyamoto, Y.1
Maitra, A.2
Ghosh, B.3
Zechner, U.4
Argani, P.5
Iacobuzio-Donahue, C.A.6
Sriuranpong, V.7
Iso, T.8
Meszoely, I.M.9
Wolfe, M.S.10
Hruban, R.H.11
Ball, D.W.12
Schmid, R.M.13
Leach, S.D.14
-
13
-
-
57749116315
-
Notch and Kras reprogram pancreaticacinar cells to ductal intraepithelial neoplasia
-
De La, O. J.; Emerson, L. L.; Goodman, J. L.; Froebe, S. C.; Illum, B. E.; Curtis, A. B.; Murtaugh, L. C. Notch and Kras reprogram pancreaticacinar cells to ductal intraepithelial neoplasia. Proc. Natl. Acad. Sci. USA, 2008, 105, 18907-18912.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18907-18912
-
-
De La, O.J.1
Emerson, L.L.2
Goodman, J.L.3
Froebe, S.C.4
Illum, B.E.5
Curtis, A.B.6
Murtaugh, L.C.7
-
14
-
-
67649313759
-
Notch and Kras in pancreatic cancer:At the crossroads of mutation, differentiation and signaling
-
De La, O. J.; Murtaugh, L. C. Notch and Kras in pancreatic cancer:at the crossroads of mutation, differentiation and signaling. Cell Cycle, 2009, 8, 1860-1864.
-
(2009)
Cell Cycle
, vol.8
, pp. 1860-1864
-
-
De La, O.J.1
Murtaugh, L.C.2
-
15
-
-
33845611029
-
Activation of Notch signalingin tumorigenesis of experimental pancreatic cancer induced by dimethylbenzanthracenein mice
-
Kimura, K.; Satoh, K.; Kanno, A.; Hamada, S.; Hirota, M.; Endoh, M.; Masamune, A.; Shimosegawa, T. Activation of Notch signalingin tumorigenesis of experimental pancreatic cancer induced by dimethylbenzanthracenein mice. Cancer Sci., 2007, 98, 155-162.
-
(2007)
Cancer Sci.
, vol.98
, pp. 155-162
-
-
Kimura, K.1
Satoh, K.2
Kanno, A.3
Hamada, S.4
Hirota, M.5
Endoh, M.6
Masamune, A.7
Shimosegawa, T.8
-
16
-
-
65249147725
-
Ligand-dependent Notch signaling is involved in tumorinitiation and tumor maintenance in pancreatic cancer
-
Mullendore, M. E.; Koorstra, J. B.; Li, Y. M.; Offerhaus, G. J.; Fan, X.; Henderson, C. M.; Matsui, W.; Eberhart, C. G.; Maitra, A.; Feldmann, G. Ligand-dependent Notch signaling is involved in tumorinitiation and tumor maintenance in pancreatic cancer. Clin. Cancer Res., 2009, 15, 2291-2301.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 2291-2301
-
-
Mullendore, M.E.1
Koorstra, J.B.2
Li, Y.M.3
Offerhaus, G.J.4
Fan, X.5
Henderson, C.M.6
Matsui, W.7
Eberhart, C.G.8
Maitra, A.9
Feldmann, G.10
-
17
-
-
37649023286
-
Matrix metalloproteinase 7 controls pancreatic acinar cell transdifferentiation by activating the Notch signaling pathway
-
Sawey, E. T.; Johnson, J. A.; Crawford, H. C. Matrix metalloproteinase 7 controls pancreatic acinar cell transdifferentiation by activating the Notch signaling pathway. Proc. Natl. Acad. Sci. USA, 2007, 104, 19327-19332.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 19327-19332
-
-
Sawey, E.T.1
Johnson, J.A.2
Crawford, H.C.3
-
18
-
-
33645049305
-
Down-regulation of Notch-1 inhibits invasion by inactivationof nuclear factor-{kappa}B, vascular endothelial growth factor, andmatrix metalloproteinase-9 in pancreatic cancer cells
-
Wang, Z.; Banerjee, S.; Li, Y.; Rahman, K. M.; Zhang, Y.; Sarkar, F. H. Down-regulation of Notch-1 inhibits invasion by inactivationof nuclear factor-{kappa}B, vascular endothelial growth factor, andmatrix metalloproteinase-9 in pancreatic cancer cells. Cancer Res., 2006, 66, 2778-2784.
-
(2006)
Cancer Res.
, vol.66
, pp. 2778-2784
-
-
Wang, Z.1
Banerjee, S.2
Li, Y.3
Rahman, K.M.4
Zhang, Y.5
Sarkar, F.H.6
-
19
-
-
33645473185
-
Down-regulation of Notch-1 contributes to cell growth inhibitionand apoptosis in pancreatic cancer cells
-
Wang, Z.; Zhang, Y.; Li, Y.; Banerjee, S.; Liao, J.; Sarkar, F. H. Down-regulation of Notch-1 contributes to cell growth inhibitionand apoptosis in pancreatic cancer cells. Mol. Cancer Ther., 2006,5, 483-493.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 483-493
-
-
Wang, Z.1
Zhang, Y.2
Li, Y.3
Banerjee, S.4
Liao, J.5
Sarkar, F.H.6
-
20
-
-
65549141305
-
Acquisition ofepithelial-mesenchymal transition phenotype of gemcitabineresistantpancreatic cancer cells is linked with activation of thenotch signaling pathway
-
Wang, Z.; Li, Y.; Kong, D.; Banerjee, S.; Ahmad, A.; Azmi, A. S. Ali, S.; Abbruzzese, J. L.; Gallick, G. E.; Sarkar, F. H. Acquisition ofepithelial-mesenchymal transition phenotype of gemcitabineresistantpancreatic cancer cells is linked with activation of thenotch signaling pathway. Cancer Res., 2009, 69, 2400-2407.
-
(2009)
Cancer Res.
, vol.69
, pp. 2400-2407
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Banerjee, S.4
Ahmad, A.5
Azmi, A.S.6
Ali, S.7
Abbruzzese, J.L.8
Gallick, G.E.9
Sarkar, F.H.10
-
21
-
-
69949087531
-
Micro RNA miR-34 inhibits human pancreatic cancertumor-initiating cells
-
Ji, Q.; Hao, X.; Zhang, M.; Tang, W.; Yang, M.; Li, L.; Xiang, D.; Desano, J. T.; Bommer, G. T.; Fan, D.; Fearon, E. R.; Lawrence, T. S.; Xu, L. Micro RNA miR-34 inhibits human pancreatic cancertumor-initiating cells. PLo S One, 2009, 4, e6816.
-
(2009)
PLo S One
, vol.4
-
-
Ji, Q.1
Hao, X.2
Zhang, M.3
Tang, W.4
Yang, M.5
Li, L.6
Xiang, D.7
Desano, J.T.8
Bommer, G.T.9
Fan, D.10
Fearon, E.R.11
Lawrence, T.S.12
Xu, L.13
-
22
-
-
0035476048
-
Dynamics of notch expression during murine prostate developmentand tumorigenesis
-
Shou, J.; Ross, S.; Koeppen, H.; de, Sauvage, F. J.; Gao, W. Q. Dynamics of notch expression during murine prostate developmentand tumorigenesis. Cancer Res., 2001, 61, 7291-7297.
-
(2001)
Cancer Res.
, vol.61
, pp. 7291-7297
-
-
Shou, J.1
Ross, S.2
Koeppen, H.3
de Sauvage, F.J.4
Gao, W.Q.5
-
23
-
-
59449107891
-
Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator
-
Bin, H. B.; Adhami, V. M.; Asim, M.; Siddiqui, I. A.; Bhat, K. M.; Zhong, W.; Saleem, M.; Din, M.; Setaluri, V.; Mukhtar, H. Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator. Clin. Cancer Res., 2009, 15, 452-459.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 452-459
-
-
Bin, H.B.1
Adhami, V.M.2
Asim, M.3
Siddiqui, I.A.4
Bhat, K.M.5
Zhong, W.6
Saleem, M.7
Din, M.8
Setaluri, V.9
Mukhtar, H.10
-
24
-
-
55449084812
-
Notch signaling: Apotential therapeutic target in prostate cancer
-
Villaronga, M. A.; Bevan, C. L.; Belandia, B. Notch signaling: apotential therapeutic target in prostate cancer. Curr. Cancer Drug Targets, 2008, 8, 566-580.
-
(2008)
Curr. Cancer Drug Targets
, vol.8
, pp. 566-580
-
-
Villaronga, M.A.1
Bevan, C.L.2
Belandia, B.3
-
25
-
-
47849127390
-
The Notch pathway in prostate developmentand cancer
-
Leong, K. G.; Gao, W. Q. The Notch pathway in prostate developmentand cancer. Differentiation, 2008, 76, 699-716.
-
(2008)
Differentiation
, vol.76
, pp. 699-716
-
-
Leong, K.G.1
Gao, W.Q.2
-
26
-
-
0942276369
-
Notch signalingand ERK activation are important for the osteomimetic propertiesof prostate cancer bone metastatic cell lines
-
Zayzafoon, M.; Abdulkadir, S. A.; McDonald, J. M. Notch signalingand ERK activation are important for the osteomimetic propertiesof prostate cancer bone metastatic cell lines. J. Biol. Chem., 2004,279, 3662-3670.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 3662-3670
-
-
Zayzafoon, M.1
Abdulkadir, S.A.2
McDonald, J.M.3
-
27
-
-
4944241544
-
JAGGED1 expression is associatedwith prostate cancer metastasis and recurrence
-
Santagata, S.; Demichelis, F.; Riva, A.; Varambally, S.; Hofer, M. D.; Kutok, J. L.; Kim, R.; Tang, J.; Montie, J. E.; Chinnaiyan, A. M.; Rubin, M. A.; Aster, J. C. JAGGED1 expression is associatedwith prostate cancer metastasis and recurrence. Cancer Res., 2004,64, 6854-6857.
-
(2004)
Cancer Res.
, vol.64
, pp. 6854-6857
-
-
Santagata, S.1
Demichelis, F.2
Riva, A.3
Varambally, S.4
Hofer, M.D.5
Kutok, J.L.6
Kim, R.7
Tang, J.8
Montie, J.E.9
Chinnaiyan, A.M.10
Rubin, M.A.11
Aster, J.C.12
-
28
-
-
33748872289
-
Down-regulation of Jagged-1 induces cell growth inhibition and Sphase arrest in prostate cancer cells
-
Zhang, Y.; Wang, Z.; Ahmed, F.; Banerjee, S.; Li, Y.; Sarkar, F. H. Down-regulation of Jagged-1 induces cell growth inhibition and Sphase arrest in prostate cancer cells. Int. J. Cancer, 2006, 119(9), 2071-2077.
-
(2006)
Int. J. Cancer
, vol.119
, Issue.9
, pp. 2071-2077
-
-
Zhang, Y.1
Wang, Z.2
Ahmed, F.3
Banerjee, S.4
Li, Y.5
Sarkar, F.H.6
-
29
-
-
34249058671
-
Restoration of p53 expression in human cancer cell lines upregulatesthe expression of Notch1: Implications for cancer cell fate determinationafter genotoxic stress
-
Alimirah, F.; Panchanathan, R.; Davis F. J.; Chen, J.; Choubey, D. Restoration of p53 expression in human cancer cell lines upregulatesthe expression of Notch1: implications for cancer cell fate determinationafter genotoxic stress. Neoplasia, 2007, 9, 427-434.
-
(2007)
Neoplasia
, vol.9
, pp. 427-434
-
-
Alimirah, F.1
Panchanathan, R.2
Davis, F.J.3
Chen, J.4
Choubey, D.5
-
30
-
-
9144239848
-
Identification of genetic pathways activatedby the androgen receptor during the induction of proliferation in theventral prostate gland
-
Nantermet, P. V.; Xu, J.; Yu, Y.; Hodor, P.; Holder, D.; Adamski, S.; Gentile, M. A.; Kimmel, D. B.; Harada, S.; Gerhold, D.; Freedman, L. P.; Ray, W. J. Identification of genetic pathways activatedby the androgen receptor during the induction of proliferation in theventral prostate gland. J. Biol. Chem., 2004, 279, 1310-1322.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 1310-1322
-
-
Nantermet, P.V.1
Xu, J.2
Yu, Y.3
Hodor, P.4
Holder, D.5
Adamski, S.6
Gentile, M.A.7
Kimmel, D.B.8
Harada, S.9
Gerhold, D.10
Freedman, L.P.11
Ray, W.J.12
-
31
-
-
13444282183
-
Hey1, a mediator of notch signaling, isan androgen receptor corepressor
-
Belandia, B.; Powell, S. M.; Garcia-Pedrero, J. M.; Walker, M. M.; Bevan. C. L.; Parker. M. G.; Hey1, a mediator of notch signaling, isan androgen receptor corepressor. Mol. Cell Biol., 2005, 25, 1425-1436.
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 1425-1436
-
-
Belandia, B.1
Powell, S.M.2
Garcia-Pedrero, J.M.3
Walker, M.M.4
Bevan, C.L.5
Parker, M.G.6
-
32
-
-
34347240929
-
Notch signaling and its role inbreast cancer
-
Wu, F.; Stutzman, A.; Mo, Y. Y. Notch signaling and its role inbreast cancer. Front Biosci., 2007, 12, 4370-4383.
-
(2007)
Front Biosci.
, vol.12
, pp. 4370-4383
-
-
Wu, F.1
Stutzman, A.2
Mo, Y.Y.3
-
33
-
-
32944470488
-
Aberrant activation ofnotch signaling in human breast cancer
-
Stylianou, S.; Clarke, R. B.; Brennan, K. Aberrant activation ofnotch signaling in human breast cancer. Cancer Res., 2006, 66, 1517-1525.
-
(2006)
Cancer Res.
, vol.66
, pp. 1517-1525
-
-
Stylianou, S.1
Clarke, R.B.2
Brennan, K.3
-
34
-
-
24944506696
-
High-level coexpressionof JAG1 and NOTCH1 is observed in human breast cancerand is associated with poor overall survival
-
Reedijk, M.; Odorcic, S.; Chang, L.; Zhang, H.; Miller, N.; McCready, D. R.; Lockwood, G.; Egan, S. E. High-level coexpressionof JAG1 and NOTCH1 is observed in human breast cancerand is associated with poor overall survival. Cancer Res., 2005, 65, 8530-8537.
-
(2005)
Cancer Res.
, vol.65
, pp. 8530-8537
-
-
Reedijk, M.1
Odorcic, S.2
Chang, L.3
Zhang, H.4
Miller, N.5
McCready, D.R.6
Lockwood, G.7
Egan, S.E.8
-
35
-
-
33646415906
-
Survivalsignaling by Notch1: Mammalian target of rapamycin(mTOR)-dependent inhibition of p53
-
Mungamuri, S. K.; Yang, X.; Thor, A. D.; Somasundaram, K. Survivalsignaling by Notch1: mammalian target of rapamycin(mTOR)-dependent inhibition of p53. Cancer Res., 2006, 66, 4715-4724.
-
(2006)
Cancer Res.
, vol.66
, pp. 4715-4724
-
-
Mungamuri, S.K.1
Yang, X.2
Thor, A.D.3
Somasundaram, K.4
-
36
-
-
63849329353
-
A functional Notch-survivin gene signaturein basal breast cancer
-
Lee, C. W.; Simin, K.; Liu, Q.; Plescia, J.; Guha, M.; Khan, A. Hsieh, C. C.; Altieri, D. C. A functional Notch-survivin gene signaturein basal breast cancer. Breast Cancer Res., 2008, 10, R97.
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Lee, C.W.1
Simin, K.2
Liu, Q.3
Plescia, J.4
Guha, M.5
Khan, A.6
Hsieh, C.C.7
Altieri, D.C.8
-
37
-
-
48549103124
-
Cross-talk between notch andthe estrogen receptor in breast cancer suggests novel therapeuticapproaches
-
Rizzo, P.; Miao, H.; D'Souza, G.; Osipo, C.; Song, L. L.; Yun, J.; Zhao, H.; Mascarenhas, J.; Wyatt, D.; Antico, G.; Hao, L.; Yao, K.; Rajan, P.; Hicks, C.; Siziopikou, K.; Selvaggi, S.; Bashir, A.; Bhandari, D.; Marchese, A.; Lendahl, U.; Qin, J. Z.; Tonetti, D. A.; Albain, K.; Nickoloff, B. J.; Miele, L. Cross-talk between notch andthe estrogen receptor in breast cancer suggests novel therapeuticapproaches. Cancer Res., 2008, 68, 5226-5235.
-
(2008)
Cancer Res.
, vol.68
, pp. 5226-5235
-
-
Rizzo, P.1
Miao, H.2
D'Souza, G.3
Osipo, C.4
Song, L.L.5
Yun, J.6
Zhao, H.7
Mascarenhas, J.8
Wyatt, D.9
Antico, G.10
Hao, L.11
Yao, K.12
Rajan, P.13
Hicks, C.14
Siziopikou, K.15
Selvaggi, S.16
Bashir, A.17
Bhandari, D.18
Marchese, A.19
Lendahl, U.20
Qin, J.Z.21
Tonetti, D.A.22
Albain, K.23
Nickoloff, B.J.24
Miele, L.25
more..
-
38
-
-
36549010842
-
Jagged1-mediated Notch activation induces epithelialto-mesenchymal transition through Slug-induced repression of Ecadherin
-
Leong, K. G.; Niessen, K.; Kulic, I.; Raouf, A.; Eaves, C.; Pollet, I.; Karsan, A. Jagged1-mediated Notch activation induces epithelialto-mesenchymal transition through Slug-induced repression of Ecadherin. J. Exp. Med., 2007, 204, 2935-2948.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2935-2948
-
-
Leong, K.G.1
Niessen, K.2
Kulic, I.3
Raouf, A.4
Eaves, C.5
Pollet, I.6
Karsan, A.7
-
39
-
-
34548833559
-
Notch2signaling induces apoptosis and inhibits human MDA-MB-231xenograft growth
-
O'Neill, C. F.; Urs, S.; Cinelli, C.; Lincoln, A.; Nadeau, R. J.; Leon, R.; Toher, J.; Mouta-Bellum, C.; Friesel, R. E.; Liaw, L. Notch2signaling induces apoptosis and inhibits human MDA-MB-231xenograft growth. Am. J. Pathol., 2007, 171, 1023-1036.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 1023-1036
-
-
O'Neill, C.F.1
Urs, S.2
Cinelli, C.3
Lincoln, A.4
Nadeau, R.J.5
Leon, R.6
Toher, J.7
Mouta-Bellum, C.8
Friesel, R.E.9
Liaw, L.10
-
40
-
-
40949092796
-
NOTCH3 signaling pathway plays crucial roles inthe proliferation of Erb B2-negative human breast cancer cells
-
Yamaguchi, N.; Oyama, T.; Ito, E.; Satoh H.; Azuma, S.; Hayashi, M.; Shimizu, K.; Honma, R.; Yanagisawa, Y.; Nishikawa, A.; Kawamura, M.; Imai, J; Ohwada, S.; Tatsuta, K,.; Inoue, J.; Semba, K.; Watanabe, S. NOTCH3 signaling pathway plays crucial roles inthe proliferation of Erb B2-negative human breast cancer cells. Cancer Res., 2008, 68, 1881-1888.
-
(2008)
Cancer Res.
, vol.68
, pp. 1881-1888
-
-
Yamaguchi, N.1
Oyama, T.2
Ito, E.3
Satoh, H.4
Azuma, S.5
Hayashi, M.6
Shimizu, K.7
Honma, R.8
Yanagisawa, Y.9
Nishikawa, A.10
Kawamura, M.11
Imai, J.12
Ohwada, S.13
Tatsuta, K.14
Inoue, J.15
Semba, K.16
Watanabe, S.17
-
41
-
-
37149013962
-
Effects of recombinant erythropoietin on breast cancer-initiatingcells
-
Phillips, T. M.; Kim, K.; Vlashi, E.; McBride, W. H.; Pajonk, F. Effects of recombinant erythropoietin on breast cancer-initiatingcells. Neoplasia, 2007, 9, 1122-1129.
-
(2007)
Neoplasia
, vol.9
, pp. 1122-1129
-
-
Phillips, T.M.1
Kim, K.2
Vlashi, E.3
McBride, W.H.4
Pajonk, F.5
-
42
-
-
36248953716
-
Mammary stem cells and breast cancer-role of Notch signalling
-
Farnie, G.; Clarke, R. B. Mammary stem cells and breast cancer-role of Notch signalling. Stem Cell Rev., 2007, 3, 169-175.
-
(2007)
Stem Cell Rev.
, vol.3
, pp. 169-175
-
-
Farnie, G.1
Clarke, R.B.2
-
43
-
-
3342979755
-
Notch in lung developmentand lung cancer
-
Collins, B. J.; Kleeberger, W.; Ball, D. W. Notch in lung developmentand lung cancer. Semin. Cancer Biol., 2004, 14, 357-364.
-
(2004)
Semin. Cancer Biol.
, vol.14
, pp. 357-364
-
-
Collins, B.J.1
Kleeberger, W.2
Ball, D.W.3
-
44
-
-
0035300448
-
Notch signaling induces cell cyclearrest in small cell lung cancer cells
-
Sriuranpong, V.; Borges, M. W.; Ravi, R. K.; Arnold, D. R.; Nelkin, B. D.; Baylin, S. B.; Ball, D. W. Notch signaling induces cell cyclearrest in small cell lung cancer cells. Cancer Res., 2001, 61, 3200-3205.
-
(2001)
Cancer Res.
, vol.61
, pp. 3200-3205
-
-
Sriuranpong, V.1
Borges, M.W.2
Ravi, R.K.3
Arnold, D.R.4
Nelkin, B.D.5
Baylin, S.B.6
Ball, D.W.7
-
45
-
-
0030974127
-
Conservation of the Drosophila lateral inhibition pathway in human lung cancer: A hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression
-
Chen, H.; Thiagalingam, A.; Chopra, H.; Borges, M. W.; Feder, J. N.; Nelkin, B. D.; Baylin, S. B.; Ball, D. W. Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression. Proc. Natl. Acad. Sci. USA, 1997, 94, 5355-5360.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5355-5360
-
-
Chen, H.1
Thiagalingam, A.2
Chopra, H.3
Borges, M.W.4
Feder, J.N.5
Nelkin, B.D.6
Baylin, S.B.7
Ball, D.W.8
-
46
-
-
34548599785
-
Oxygen concentration determines the biologicaleffects of NOTCH-1 signaling in adenocarcinoma of thelung
-
Chen, Y.; De, Marco M. A.; Graziani, I.; Gazdar, A. F.; Strack, P. R.; Miele, L.; Bocchetta, M. Oxygen concentration determines the biologicaleffects of NOTCH-1 signaling in adenocarcinoma of thelung. Cancer Res., 2007, 67, 7954-7959.
-
(2007)
Cancer Res.
, vol.67
, pp. 7954-7959
-
-
Chen, Y.1
De Marco, M.A.2
Graziani, I.3
Gazdar, A.F.4
Strack, P.R.5
Miele, L.6
Bocchetta, M.7
-
47
-
-
0037417132
-
Constitutive activation of Notch3 inhibits terminal epithelialdifferentiation in lungs of transgenic mice
-
Dang, T. P.; Eichenberger, S.; Gonzalez, A.; Olson, S.; Carbone, D. P. Constitutive activation of Notch3 inhibits terminal epithelialdifferentiation in lungs of transgenic mice. Oncogene, 2003, 22, 1988-1997.
-
(2003)
Oncogene
, vol.22
, pp. 1988-1997
-
-
Dang, T.P.1
Eichenberger, S.2
Gonzalez, A.3
Olson, S.4
Carbone, D.P.5
-
48
-
-
0034674896
-
Chromosome 19translocation, overexpression of Notch3, and human lung cancer
-
Dang, T. P.; Gazdar, A. F.; Virmani, A. K.; Sepetavec, T.; Hande, K. R.; Minna, J. D.; Roberts, J. R.; Carbone, D. P. Chromosome 19translocation, overexpression of Notch3, and human lung cancer. J. Natl. Cancer Inst., 2000, 92, 1355-1357.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1355-1357
-
-
Dang, T.P.1
Gazdar, A.F.2
Virmani, A.K.3
Sepetavec, T.4
Hande, K.R.5
Minna, J.D.6
Roberts, J.R.7
Carbone, D.P.8
-
49
-
-
34548572895
-
Gamma-secretase inhibitor preventsNotch3 activation and reduces proliferation in human lung cancers
-
Konishi, J.; Kawaguchi, K. S.; Vo, H.; Haruki, N.; Gonzalez, A.; Carbone, D. P.; Dang, T. P. Gamma-secretase inhibitor preventsNotch3 activation and reduces proliferation in human lung cancers. Cancer Res., 2007, 67, 8051-8057.
-
(2007)
Cancer Res.
, vol.67
, pp. 8051-8057
-
-
Konishi, J.1
Kawaguchi, K.S.2
Vo, H.3
Haruki, N.4
Gonzalez, A.5
Carbone, D.P.6
Dang, T.P.7
-
50
-
-
18144426777
-
Dominantnegative Notch3 receptor inhibits mitogen-activated protein kinasepathway and the growth of human lung cancers
-
Haruki, N.; Kawaguchi, K. S.; Eichenberger, S.; Massion, P. P.; Olson, S.; Gonzalez, A.; Carbone, D. P.; Dang, T. P. Dominantnegative Notch3 receptor inhibits mitogen-activated protein kinasepathway and the growth of human lung cancers. Cancer Res., 2005,65, 3555-3561.
-
(2005)
Cancer Res.
, vol.65
, pp. 3555-3561
-
-
Haruki, N.1
Kawaguchi, K.S.2
Eichenberger, S.3
Massion, P.P.4
Olson, S.5
Gonzalez, A.6
Carbone, D.P.7
Dang, T.P.8
-
51
-
-
15544381570
-
Self-renewal and cancer of the gut: Twosides of a coin
-
Radtke, F.; Clevers, H. Self-renewal and cancer of the gut: twosides of a coin. Science, 2005, 307, 1904-1909.
-
(2005)
Science
, vol.307
, pp. 1904-1909
-
-
Radtke, F.1
Clevers, H.2
-
52
-
-
59049088446
-
Activationof Notch signaling in human colon adenocarcinoma
-
Reedijk, M.; Odorcic, S.; Zhang, H.; Chetty, R.; Tennert, C.; Dickson, B. C.; Lockwood, G.; Gallinger, S.; Egan, S. E. Activationof Notch signaling in human colon adenocarcinoma. Int. J. Oncol., 2008, 33, 1223-1229.
-
(2008)
Int. J. Oncol.
, vol.33
, pp. 1223-1229
-
-
Reedijk, M.1
Odorcic, S.2
Zhang, H.3
Chetty, R.4
Tennert, C.5
Dickson, B.C.6
Lockwood, G.7
Gallinger, S.8
Egan, S.E.9
-
53
-
-
37349088615
-
Gammasecretaseinhibitors enhance taxane-induced mitotic arrest andapoptosis in colon cancer cells
-
Akiyoshi, T.; Nakamura, M.; Yanai, K.; Nagai, S.; Wada, J.; Koga, K.; Nakashima, H.; Sato, N.; Tanaka, M.; Katano, M. Gammasecretaseinhibitors enhance taxane-induced mitotic arrest andapoptosis in colon cancer cells. Gastroenterology, 2008, 134, 131-144.
-
(2008)
Gastroenterology
, vol.134
, pp. 131-144
-
-
Akiyoshi, T.1
Nakamura, M.2
Yanai, K.3
Nagai, S.4
Wada, J.5
Koga, K.6
Nakashima, H.7
Sato, N.8
Tanaka, M.9
Katano, M.10
-
54
-
-
65549086537
-
Notch and Wnt signals cooperativelycontrol cell proliferation and tumorigenesis in the intestine
-
Fre, S.; Pallavi, S. K.; Huyghe, M.; Lae, M.; Janssen, K. P.; Robine, S.; Rtavanis-Tsakonas, S.; Louvard, D. Notch and Wnt signals cooperativelycontrol cell proliferation and tumorigenesis in the intestine. Proc. Natl. Acad. Sci. USA, 2009, 106, 6309-6314.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 6309-6314
-
-
Fre, S.1
Pallavi, S.K.2
Huyghe, M.3
Lae, M.4
Janssen, K.P.5
Robine, S.6
Rtavanis-Tsakonas, S.7
Louvard, D.8
-
55
-
-
58349091690
-
Gamma-Secretase inhibitors abrogateoxaliplatin-induced activation of the Notch-1 signaling pathway incolon cancer cells resulting in enhanced chemosensitivity
-
Meng, R. D.; Shelton, C. C.; Li, Y. M; Qin, L. X.; Notterman, D.; Paty, P. B.; Schwartz, G. K. Gamma-Secretase inhibitors abrogateoxaliplatin-induced activation of the Notch-1 signaling pathway incolon cancer cells resulting in enhanced chemosensitivity. Cancer Res., 2009, 69, 573-582.
-
(2009)
Cancer Res.
, vol.69
, pp. 573-582
-
-
Meng, R.D.1
Shelton, C.C.2
Li, Y.M.3
Qin, L.X.4
Notterman, D.5
Paty, P.B.6
Schwartz, G.K.7
-
56
-
-
57749110620
-
Notch inhibits expression of the Kruppel-like factor 4tumor suppressor in the intestinal epithelium
-
Ghaleb, A. M.; Aggarwal, G.; Bialkowska, A. B.; Nandan, M. O.; Yang, V. W. Notch inhibits expression of the Kruppel-like factor 4tumor suppressor in the intestinal epithelium. Mol. Cancer Res., 2008, 6, 1920-1927.
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 1920-1927
-
-
Ghaleb, A.M.1
Aggarwal, G.2
Bialkowska, A.B.3
Nandan, M.O.4
Yang, V.W.5
-
57
-
-
38149015554
-
Suppressionof renal cell carcinoma growth by inhibition of Notch signaling invitro and in vivo
-
Sjolund, J.; Johansson, M.; Manna, S.; Norin, C.; Pietras, A.; Beckman, S.; Nilsson, E.; Ljungberg, B.; Axelson, H. Suppressionof renal cell carcinoma growth by inhibition of Notch signaling invitro and in vivo. J. Clin. Invest., 2008, 118, 217-228.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 217-228
-
-
Sjolund, J.1
Johansson, M.2
Manna, S.3
Norin, C.4
Pietras, A.5
Beckman, S.6
Nilsson, E.7
Ljungberg, B.8
Axelson, H.9
-
58
-
-
25444506836
-
Up-regulation of delta-like 4 ligand in human tumorvasculature and the role of basal expression in endothelial cellfunction
-
Patel, N. S.; Li, J. L.; Generali, D.; Poulsom, R.; Cranston, D. W.; Harris, A. L. Up-regulation of delta-like 4 ligand in human tumorvasculature and the role of basal expression in endothelial cellfunction. Cancer Res., 2005, 65, 8690-8697.
-
(2005)
Cancer Res.
, vol.65
, pp. 8690-8697
-
-
Patel, N.S.1
Li, J.L.2
Generali, D.3
Poulsom, R.4
Cranston, D.W.5
Harris, A.L.6
-
59
-
-
68849097965
-
Expression and clinical significance of Notch receptors in humanrenal cell carcinoma
-
Sun, S.; Du, R.; Gao, J.; Ning, X.; Xie, H.; Lin, X.; Liu, J.; Fan, D. Expression and clinical significance of Notch receptors in humanrenal cell carcinoma. Pathology, 2009, 41, 335-341.
-
(2009)
Pathology
, vol.41
, pp. 335-341
-
-
Sun, S.1
Du, R.2
Gao, J.3
Ning, X.4
Xie, H.5
Lin, X.6
Liu, J.7
Fan, D.8
-
60
-
-
0346365362
-
Notch1 signaling inhibits growth of human hepatocellularcarcinoma through induction of cell cycle arrest and apoptosis
-
Qi, R.; An, H.; Yu, Y.; Zhang, M.; Liu, S.; Xu, H.; Guo, Z.; Cheng, T.; Cao, X. Notch1 signaling inhibits growth of human hepatocellularcarcinoma through induction of cell cycle arrest and apoptosis. Cancer Res., 2003, 63, 8323-8329.
-
(2003)
Cancer Res.
, vol.63
, pp. 8323-8329
-
-
Qi, R.1
An, H.2
Yu, Y.3
Zhang, M.4
Liu, S.5
Xu, H.6
Guo, Z.7
Cheng, T.8
Cao, X.9
-
61
-
-
67650236862
-
Notch1 signaling sensitizes tumor necrosis factor-relatedapoptosis-inducing ligand-induced apoptosis in human hepatocellularcarcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradationand up-regulating p53-dependent DR5 expression
-
Wang, C.; Qi, R.; Li, N.; Wang, Z.; An, H.; Zhang, Q.; Yu, Y.; Cao, X. Notch1 signaling sensitizes tumor necrosis factor-relatedapoptosis-inducing ligand-induced apoptosis in human hepatocellularcarcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradationand up-regulating p53-dependent DR5 expression. J. Biol. Chem., 2009, 284, 16183-16190.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16183-16190
-
-
Wang, C.1
Qi, R.2
Li, N.3
Wang, Z.4
An, H.5
Zhang, Q.6
Yu, Y.7
Cao, X.8
-
62
-
-
42349090918
-
Inhibition of gammasecretaseaffects proliferation of leukemia and hepatoma cell linesthrough Notch signaling
-
Suwanjunee, S.; Wongchana, W.; Palaga, T. Inhibition of gammasecretaseaffects proliferation of leukemia and hepatoma cell linesthrough Notch signaling. Anticancer Drugs, 2008, 19, 477-486.
-
(2008)
Anticancer Drugs
, vol.19
, pp. 477-486
-
-
Suwanjunee, S.1
Wongchana, W.2
Palaga, T.3
-
63
-
-
33745630080
-
Notch3 intracellular domain accumulates in Hep G2 cell line
-
Giovannini, C.; Lacchini, M.; Gramantieri, L.; Chieco, P.; Bolondi, L. Notch3 intracellular domain accumulates in Hep G2 cell line. Anti Cancer Res., 2006, 26, 2123-2127.
-
(2006)
Anti Cancer Res.
, vol.26
, pp. 2123-2127
-
-
Giovannini, C.1
Lacchini, M.2
Gramantieri, L.3
Chieco, P.4
Bolondi, L.5
-
64
-
-
33749012860
-
The role of the vascular endothelial growthfactor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vesselremodeling and endothelial cell functions
-
Hainaud, P.; Contreres, J. O.; Villemain, A.; Liu, L. X.; Plouet, J.; Tobelem, G.; Dupuy, E. The role of the vascular endothelial growthfactor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vesselremodeling and endothelial cell functions. Cancer Res., 2006,66, 8501-8510.
-
(2006)
Cancer Res.
, vol.66
, pp. 8501-8510
-
-
Hainaud, P.1
Contreres, J.O.2
Villemain, A.3
Liu, L.X.4
Plouet, J.5
Tobelem, G.6
Dupuy, E.7
-
65
-
-
70449732855
-
Expression of Notch1, Jagged1 and beta-catenin and their clinicopathologicalsignificance in hepatocellular carcinoma
-
Wang, M.; Xue, L.; Cao, Q.; Lin, Y.; Ding, Y.; Yang, P.; Che, L. Expression of Notch1, Jagged1 and beta-catenin and their clinicopathologicalsignificance in hepatocellular carcinoma. Neoplasma, 2009, 56, 533-541.
-
(2009)
Neoplasma
, vol.56
, pp. 533-541
-
-
Wang, M.1
Xue, L.2
Cao, Q.3
Lin, Y.4
Ding, Y.5
Yang, P.6
Che, L.7
-
66
-
-
38049150094
-
Deregulated expression of Notch receptors in human hepatocellularcarcinoma
-
Gao, J.; Song, Z.; Chen, Y.; Xia, L.; Wang, J.; Fan, R.; Du, R.; Zhang, F.; Hong, L.; Song, J.; Zou, X.; Xu, H.; Zheng, G.; Liu, J.; Fan, D. Deregulated expression of Notch receptors in human hepatocellularcarcinoma. Dig. Liver Dis., 2008, 40, 114-121.
-
(2008)
Dig. Liver Dis.
, vol.40
, pp. 114-121
-
-
Gao, J.1
Song, Z.2
Chen, Y.3
Xia, L.4
Wang, J.5
Fan, R.6
Du, R.7
Zhang, F.8
Hong, L.9
Song, J.10
Zou, X.11
Xu, H.12
Zheng, G.13
Liu, J.14
Fan, D.15
-
67
-
-
33947411967
-
Expression of Jagged1 and itsassociation with hepatitis B virus X protein in hepatocellular carcinoma
-
Gao, J.; Chen, C.; Hong, L.; Wang, J.; Du, Y.; Song, J.; Shao, X.; Zhang, J.; Han, H.; Liu, J.; Fan, D. Expression of Jagged1 and itsassociation with hepatitis B virus X protein in hepatocellular carcinoma. Biochem. Biophys. Res. Commun., 2007, 356, 341-347.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.356
, pp. 341-347
-
-
Gao, J.1
Chen, C.2
Hong, L.3
Wang, J.4
Du, Y.5
Song, J.6
Shao, X.7
Zhang, J.8
Han, H.9
Liu, J.10
Fan, D.11
-
68
-
-
34547867407
-
Aberrant Notch3 andNotch4 expression in human hepatocellular carcinoma
-
Gramantieri, L.; Giovannini, C.; Lanzi, A.; Chieco, P.; Ravaioli, M.; Venturi, A.; Grazi, G. L.; Bolondi, L. Aberrant Notch3 andNotch4 expression in human hepatocellular carcinoma. Liver Int., 2007, 27, 997-1007.
-
(2007)
Liver Int.
, vol.27
, pp. 997-1007
-
-
Gramantieri, L.1
Giovannini, C.2
Lanzi, A.3
Chieco, P.4
Ravaioli, M.5
Venturi, A.6
Grazi, G.L.7
Bolondi, L.8
-
69
-
-
33747072601
-
Aspartyl-asparagyl beta hydroxylaseover-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms
-
Cantarini, M. C.; de la Monte, S. M.; Pang, M.; Tong, M.; D'Errico, A.; Trevisani, F.; Wands, J. R. Aspartyl-asparagyl beta hydroxylaseover-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms. Hepatology, 2006, 44, 446-457.
-
(2006)
Hepatology
, vol.44
, pp. 446-457
-
-
Cantarini, M.C.1
de la Monte, S.M.2
Pang, M.3
Tong, M.4
D'Errico, A.5
Trevisani, F.6
Wands, J.R.7
-
70
-
-
0025856717
-
TAN-1, the human homolog of the Drosophilanotch gene, is broken by chromosomal translocations in Tlymphoblastic neoplasms
-
Ellisen, L. W.; Bird, J.; West, D. C.; Soreng, A. L.; Reynolds, T. C.; Smith, S. D.; Sklar, J. TAN-1, the human homolog of the Drosophilanotch gene, is broken by chromosomal translocations in Tlymphoblastic neoplasms. Cell, 1991, 66, 649-661.
-
(1991)
Cell
, vol.66
, pp. 649-661
-
-
Ellisen, L.W.1
Bird, J.2
West, D.C.3
Soreng, A.L.4
Reynolds, T.C.5
Smith, S.D.6
Sklar, J.7
-
71
-
-
50849085425
-
It's T-ALL aboutNotch
-
Demarest, R. M.; Ratti, F.; Capobianco, A. J. It's T-ALL aboutNotch. Oncogene, 2008, 27, 5082-5091.
-
(2008)
Oncogene
, vol.27
, pp. 5082-5091
-
-
Demarest, R.M.1
Ratti, F.2
Capobianco, A.J.3
-
72
-
-
68749088356
-
Notch inhibition and glucocorticoid therapyin T-cell acute lymphoblastic leukemia
-
Real, PJ.; Ferrando, A. A. Notch inhibition and glucocorticoid therapyin T-cell acute lymphoblastic leukemia. Leukemia, 2009, 23, 1374-1377.
-
(2009)
Leukemia
, vol.23
, pp. 1374-1377
-
-
Real, P.J.1
Ferrando, A.A.2
-
73
-
-
33646366173
-
Notch 1 activation in the molecularpathogenesis of T-cell acute lymphoblastic leukaemia
-
Grabher, C.; von, B. H.; Look AT. Notch 1 activation in the molecularpathogenesis of T-cell acute lymphoblastic leukaemia. Nat. Rev. Cancer, 2006, 6, 347-359.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 347-359
-
-
Grabher, C.1
von, B.H.2
Look, A.T.3
-
74
-
-
42049103185
-
Notch signaling in leukemiasand lymphomas
-
Jundt, F.; Schwarzer, R.; Dorken, B. Notch signaling in leukemiasand lymphomas. Curr. Mol. Med., 2008, 8, 51-59.
-
(2008)
Curr. Mol. Med.
, vol.8
, pp. 51-59
-
-
Jundt, F.1
Schwarzer, R.2
Dorken, B.3
-
75
-
-
33845595633
-
Notch signaling enhances nestin expressionin gliomas
-
Shih, A. H.; Holland, E. C. Notch signaling enhances nestin expressionin gliomas. Neoplasia, 2006, 8, 1072-1082.
-
(2006)
Neoplasia
, vol.8
, pp. 1072-1082
-
-
Shih, A.H.1
Holland, E.C.2
-
76
-
-
33847666952
-
Contribution of Notch signalingactivation to human glioblastoma multiforme
-
Kanamori, M.; Kawaguchi, T.; Nigro, J. M.; Feuerstein, B. G.; Berger, M. S.; Miele, L.; Pieper, R. O. Contribution of Notch signalingactivation to human glioblastoma multiforme. J. Neurosurg., 2007, 106, 417-427.
-
(2007)
J. Neurosurg.
, vol.106
, pp. 417-427
-
-
Kanamori, M.1
Kawaguchi, T.2
Nigro, J.M.3
Feuerstein, B.G.4
Berger, M.S.5
Miele, L.6
Pieper, R.O.7
-
77
-
-
58649120268
-
A role for the transcription factorHEY1 in glioblastoma
-
Hulleman, E.; Quarto, M.; Vernell, R.; Masserdotti, G.; Colli, E.; Kros, J. M.; Levi, D.; Gaetani, P.; Tunici, P.; Finocchiaro, G.; Baena, R. R.; Capra, M.; Helin, K. A role for the transcription factorHEY1 in glioblastoma. J. Cell Mol. Med., 2009, 13, 136-146.
-
(2009)
J. Cell Mol. Med.
, vol.13
, pp. 136-146
-
-
Hulleman, E.1
Quarto, M.2
Vernell, R.3
Masserdotti, G.4
Colli, E.5
Kros, J.M.6
Levi, D.7
Gaetani, P.8
Tunici, P.9
Finocchiaro, G.10
Baena, R.R.11
Capra, M.12
Helin, K.13
-
78
-
-
58349102939
-
Tenascin-C is a novel RBPJkappa-induced target gene for Notchsignaling in gliomas
-
Sivasankaran, B.; Degen, M.; Ghaffari, A.; Hegi, M. E.; Hamou, M. F.; Ionescu, M. C.; Zweifel, C.; Tolnay, M.; Wasner, M.; Mergenthaler, S.; Miserez, A. R.; Kiss, R.; Lino, M. M.; Merlo, A. Tenascin-C is a novel RBPJkappa-induced target gene for Notchsignaling in gliomas. Cancer Res., 2009, 69, 458-465.
-
(2009)
Cancer Res.
, vol.69
, pp. 458-465
-
-
Sivasankaran, B.1
Degen, M.2
Ghaffari, A.3
Hegi, M.E.4
Hamou, M.F.5
Ionescu, M.C.6
Zweifel, C.7
Tolnay, M.8
Wasner, M.9
Mergenthaler, S.10
Miserez, A.R.11
Kiss, R.12
Lino, M.M.13
Merlo, A.14
-
79
-
-
34547095240
-
Spontaneous transformation of human adult nontumorigenicstem cells to cancer stem cells is driven by genomic instabilityin a human model of glioblastoma
-
Shiras, A.; Chettiar, S. T.; Shepal, V.; Rajendran, G.; Prasad, G. R.; Shastry, P. Spontaneous transformation of human adult nontumorigenicstem cells to cancer stem cells is driven by genomic instabilityin a human model of glioblastoma. Stem Cells, 2007, 25, 1478-1489.
-
(2007)
Stem Cells
, vol.25
, pp. 1478-1489
-
-
Shiras, A.1
Chettiar, S.T.2
Shepal, V.3
Rajendran, G.4
Prasad, G.R.5
Shastry, P.6
-
80
-
-
48749083583
-
Inhibitor of differentiation 4 drives brain tumor-initiating cellgenesis through cyclin E and notch signaling
-
Jeon, H. M.; Jin, X.; Lee, J. S.; Oh, S. Y.; Sohn, Y. W.; Park, H. J.; Joo, K. M.; Park, W. Y.; Nam, D. H.; De Pinho, R. A.; Chin, L.; Kim, H. Inhibitor of differentiation 4 drives brain tumor-initiating cellgenesis through cyclin E and notch signaling. Genes. Dev., 2008,22, 2028-2033.
-
(2008)
Genes. Dev.
, vol.22
, pp. 2028-2033
-
-
Jeon, H.M.1
Jin, X.2
Lee, J.S.3
Oh, S.Y.4
Sohn, Y.W.5
Park, H.J.6
Joo, K.M.7
Park, W.Y.8
Nam, D.H.9
De Pinho, R.A.10
Chin, L.11
Kim, H.12
-
81
-
-
70350221952
-
Micro RNA-34a inhibits glioblastomagrowth by targeting multiple oncogenes
-
Li, Y.; Guessous, F.; Zhang, Y.; Dipierro, C.; Kefas, B.; Johnson, E.; Marcinkiewicz, L.; Jiang, J.; Yang, Y.; Schmittgen, T. D.; Lopes, B.; Schiff, D.; Purow, B. Micro RNA-34a inhibits glioblastomagrowth by targeting multiple oncogenes. Cancer Res., 2009,69, 7569.
-
(2009)
Cancer Res.
, vol.69
, pp. 7569
-
-
Li, Y.1
Guessous, F.2
Zhang, Y.3
Dipierro, C.4
Kefas, B.5
Johnson, E.6
Marcinkiewicz, L.7
Jiang, J.8
Yang, Y.9
Schmittgen, T.D.10
Lopes, B.11
Schiff, D.12
Purow, B.13
-
82
-
-
0030927183
-
The link between integration and expression of human papillomavirustype 16 genomes and cellular changes in the evolution ofcervical intraepithelial neoplastic lesions
-
Daniel, B.; Rangarajan, A.; Mukherjee, G.; Vallikad, E.; Krishna, S. The link between integration and expression of human papillomavirustype 16 genomes and cellular changes in the evolution ofcervical intraepithelial neoplastic lesions. J. Gen. Virol., 1997, 78(Pt 5), 1095-1101.
-
(1997)
J. Gen. Virol.
, vol.78
, Issue.PART 5
, pp. 1095-1101
-
-
Daniel, B.1
Rangarajan, A.2
Mukherjee, G.3
Vallikad, E.4
Krishna, S.5
-
83
-
-
53249103473
-
Notch-1 associates with IKKalpha and regulatesIKK activity in cervical cancer cells
-
Song, L. L.; Peng, Y.; Yun, J.; Rizzo, P.; Chaturvedi, V.; Weijzen, S.; Kast, W. M.; Stone, P. J.; Santos, L.; Loredo, A.; Lendahl, U.; Sonenshein, G.; Osborne, B.; Qin, J. Z.; Pannuti, A.; Nickoloff, B. J.; Miele, L. Notch-1 associates with IKKalpha and regulatesIKK activity in cervical cancer cells. Oncogene, 2008, 27, 5833-5844.
-
(2008)
Oncogene
, vol.27
, pp. 5833-5844
-
-
Song, L.L.1
Peng, Y.2
Yun, J.3
Rizzo, P.4
Chaturvedi, V.5
Weijzen, S.6
Kast, W.M.7
Stone, P.J.8
Santos, L.9
Loredo, A.10
Lendahl, U.11
Sonenshein, G.12
Osborne, B.13
Qin, J.Z.14
Pannuti, A.15
Nickoloff, B.J.16
Miele, L.17
-
84
-
-
0029078323
-
Alterations in Notch signaling in neoplasticlesions of the human cervix
-
Zagouras, P.; Stifani, S.; Blaumueller, C. M.; Carcangiu, M. L.; rtavanis-Tsakonas, S. Alterations in Notch signaling in neoplasticlesions of the human cervix. Proc. Natl. Acad. Sci. USA, 1995, 92, 6414-6418.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6414-6418
-
-
Zagouras, P.1
Stifani, S.2
Blaumueller, C.M.3
Carcangiu, M.L.4
Rtavanis-Tsakonas, S.5
-
85
-
-
78651338072
-
Expression ofNotch intracellular domain in cervical cancer and effect of DAPTon cervical cancer cell
-
Sun, X. M.; Wen, H. W.; Chen, C. L.; Liao, Q. P. Expression ofNotch intracellular domain in cervical cancer and effect of DAPTon cervical cancer cell. Zhonghua Fu Chan Ke Za Zhi, 2009, 44,369-373.
-
(2009)
Zhonghua Fu Chan Ke Za Zhi
, vol.44
, pp. 369-373
-
-
Sun, X.M.1
Wen, H.W.2
Chen, C.L.3
Liao, Q.P.4
-
86
-
-
0037362373
-
HPV16E6 and E7 oncoproteins regulate Notch-1 expression and cooperateto induce transformation
-
Weijzen, S.; Zlobin, A.; Braid, M.; Miele, L.; Kast, W. M. HPV16E6 and E7 oncoproteins regulate Notch-1 expression and cooperateto induce transformation. J. Cell Physiol., 2003, 194, 356-362.
-
(2003)
J. Cell Physiol.
, vol.194
, pp. 356-362
-
-
Weijzen, S.1
Zlobin, A.2
Braid, M.3
Miele, L.4
Kast, W.M.5
-
87
-
-
33846392694
-
Coexpression of Notch1 and NF-kappaB signaling pathwaycomponents in human cervical cancer progression
-
Ramdass, B.; Maliekal, T.; Lakshmi, S.; Rehman, M.; Rema, P.; Nair, P.; Mukherjee, G.; Reddy, B. K.; Krishna, S.; Radhakrishna, P. M. Coexpression of Notch1 and NF-kappaB signaling pathwaycomponents in human cervical cancer progression. Gynecol. Oncol., 2007, 104, 352-361.
-
(2007)
Gynecol. Oncol.
, vol.104
, pp. 352-361
-
-
Ramdass, B.1
Maliekal, T.2
Lakshmi, S.3
Rehman, M.4
Rema, P.5
Nair, P.6
Mukherjee, G.7
Reddy, B.K.8
Krishna, S.9
Radhakrishna, P.M.10
-
88
-
-
35948943021
-
Overexpressedactive Notch1 induces cell growth arrest of He La cervicalcarcinoma cells
-
Wang, L.; Qin, H.; Chen, B.; Xin, X.; Li, J.; Han, H. Overexpressedactive Notch1 induces cell growth arrest of He La cervicalcarcinoma cells. Int. J. Gynecol. Cancer, 2007, 17, 1283-1292.
-
(2007)
Int. J. Gynecol. Cancer
, vol.17
, pp. 1283-1292
-
-
Wang, L.1
Qin, H.2
Chen, B.3
Xin, X.4
Li, J.5
Han, H.6
-
89
-
-
16244418366
-
Constitutively active Notch1induces growth arrest of HPV-positive cervical cancer cells viaseparate signaling pathways
-
Talora, C.; Cialfi, S.; Segatto, O.; Morrone, S.; Kim, C. J.; Frati, L.; Paolo, D. G.; Gulino, A.; Screpanti, I. Constitutively active Notch1induces growth arrest of HPV-positive cervical cancer cells viaseparate signaling pathways. Exp. Cell Res., 2005, 305, 343-354.
-
(2005)
Exp. Cell Res.
, vol.305
, pp. 343-354
-
-
Talora, C.1
Cialfi, S.2
Segatto, O.3
Morrone, S.4
Kim, C.J.5
Frati, L.6
Paolo, D.G.7
Gulino, A.8
Screpanti, I.9
-
90
-
-
0036713311
-
Specific downmodulationof Notch1 signaling in cervical cancer cells is requiredfor sustained HPV-E6/E7 expression and late steps of malignanttransformation
-
Talora, C.; Sgroi, D. C.; Crum, C. P.; Dotto, G. P. Specific downmodulationof Notch1 signaling in cervical cancer cells is requiredfor sustained HPV-E6/E7 expression and late steps of malignanttransformation. Genes. Dev., 2002, 16, 2252-2263.
-
(2002)
Genes. Dev.
, vol.16
, pp. 2252-2263
-
-
Talora, C.1
Sgroi, D.C.2
Crum, C.P.3
Dotto, G.P.4
-
91
-
-
33947230629
-
Notch1 induces cellcycle arrest and apoptosis in human cervical cancer cells: Involvementof nuclear factor kappa B inhibition
-
Yao, J.; Duan, L.; Fan, M.; Yuan, J.; Wu, X. Notch1 induces cellcycle arrest and apoptosis in human cervical cancer cells: involvementof nuclear factor kappa B inhibition. Int. J. Gynecol. Cancer, 2007, 17, 502-510.
-
(2007)
Int. J. Gynecol. Cancer
, vol.17
, pp. 502-510
-
-
Yao, J.1
Duan, L.2
Fan, M.3
Yuan, J.4
Wu, X.5
-
92
-
-
50849117455
-
The role of Notch signaling in human cervical cancer: Implicationsfor solid tumors
-
Maliekal, T. T.; Bajaj, J.; Giri, V.; Subramanyam, D.; Krishna, S. The role of Notch signaling in human cervical cancer: implicationsfor solid tumors. Oncogene, 2008, 27, 5110-5114.
-
(2008)
Oncogene
, vol.27
, pp. 5110-5114
-
-
Maliekal, T.T.1
Bajaj, J.2
Giri, V.3
Subramanyam, D.4
Krishna, S.5
-
93
-
-
67449088876
-
Expressionand Significance of Notch1 and PTEN in Gastric Cancer
-
Li, D. W.; Wu, Q.; Peng, Z. H.; Yang, Z. R.; Wang, Y. Expressionand Significance of Notch1 and PTEN in Gastric Cancer. Ai Zheng, 2007, 26, 1183-1187.
-
(2007)
Ai Zheng
, vol.26
, pp. 1183-1187
-
-
Li, D.W.1
Wu, Q.2
Peng, Z.H.3
Yang, Z.R.4
Wang, Y.5
-
94
-
-
67449168389
-
The activated Notch1 signalpathway is associated with gastric cancer progression through cyclooxygenase-2
-
Yeh, T. S.; Wu, C. W.; Hsu, K. W.; Liao, W. J.; Yang, M. C.; Li, A. F.; Wang, A. M.; Kuo, M. L.; Chi, C. W. The activated Notch1 signalpathway is associated with gastric cancer progression through cyclooxygenase-2. Cancer Res., 2009, 69, 5039-5048.
-
(2009)
Cancer Res.
, vol.69
, pp. 5039-5048
-
-
Yeh, T.S.1
Wu, C.W.2
Hsu, K.W.3
Liao, W.J.4
Yang, M.C.5
Li, A.F.6
Wang, A.M.7
Kuo, M.L.8
Chi, C.W.9
-
95
-
-
53949090314
-
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
-
Ji, Q.; Hao, X.; Meng, Y.; Zhang, M.; Desano, J.; Fan, D.; Xu, L. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer, 2008, 8, 266.
-
(2008)
BMC Cancer
, vol.8
, pp. 266
-
-
Ji, Q.1
Hao, X.2
Meng, Y.3
Zhang, M.4
Desano, J.5
Fan, D.6
Xu, L.7
-
96
-
-
34548452775
-
Tumor suppressor role of Notch-1signaling in neuroendocrine tumors
-
Kunnimalaiyaan, M.; Chen, H. Tumor suppressor role of Notch-1signaling in neuroendocrine tumors. Oncologist, 2007, 12, 535-542.
-
(2007)
Oncologist
, vol.12
, pp. 535-542
-
-
Kunnimalaiyaan, M.1
Chen, H.2
-
97
-
-
50849100996
-
The many facets ofNotch ligands
-
D'Souza, B.; Miyamoto, A.; Weinmaster, G. The many facets ofNotch ligands. Oncogene, 2008, 27, 5148-5167.
-
(2008)
Oncogene
, vol.27
, pp. 5148-5167
-
-
D'Souza, B.1
Miyamoto, A.2
Weinmaster, G.3
-
98
-
-
50849103301
-
Notch signaling regulatestumor angiogenesis by diverse mechanisms
-
Dufraine, J.; Funahashi, Y.; Kitajewski, J. Notch signaling regulatestumor angiogenesis by diverse mechanisms. Oncogene, 2008,27, 5132-5137.
-
(2008)
Oncogene
, vol.27
, pp. 5132-5137
-
-
Dufraine, J.1
Funahashi, Y.2
Kitajewski, J.3
-
99
-
-
41349095228
-
Inhibition of Notch signaling induces apoptosis ofmyeloma cells and enhances sensitivity to chemotherapy
-
Nefedova, Y.; Sullivan, D. M.; Bolick, S. C.; Dalton, W. S.; Gabrilovich, D. I. Inhibition of Notch signaling induces apoptosis ofmyeloma cells and enhances sensitivity to chemotherapy. Blood, 2008, 111, 2220-2229.
-
(2008)
Blood
, vol.111
, pp. 2220-2229
-
-
Nefedova, Y.1
Sullivan, D.M.2
Bolick, S.C.3
Dalton, W.S.4
Gabrilovich, D.I.5
-
100
-
-
27144512725
-
Gamma secretase inhibitor blocks Notch activationand induces apoptosis in Kaposi's sarcoma tumor cells
-
Curry, C. L.; Reed, L. L.; Golde, T. E.; Miele, L.; Nickoloff, B. J.; Foreman, KE. Gamma secretase inhibitor blocks Notch activationand induces apoptosis in Kaposi's sarcoma tumor cells. Oncogene, 2005, 24, 6333-6344.
-
(2005)
Oncogene
, vol.24
, pp. 6333-6344
-
-
Curry, C.L.1
Reed, L.L.2
Golde, T.E.3
Miele, L.4
Nickoloff, B.J.5
Foreman, K.E.6
-
101
-
-
50649125794
-
Erb B-2 inhibition activates Notch-1 and sensitizesbreast cancer cells to a gamma-secretase inhibitor
-
Osipo, C.; Patel, P.; Rizzo, P.; Clementz, A. G.; Hao, L.; Golde, T. E.; Miele, L. Erb B-2 inhibition activates Notch-1 and sensitizesbreast cancer cells to a gamma-secretase inhibitor. Oncogene, 2008, 27, 5019-5032.
-
(2008)
Oncogene
, vol.27
, pp. 5019-5032
-
-
Osipo, C.1
Patel, P.2
Rizzo, P.3
Clementz, A.G.4
Hao, L.5
Golde, T.E.6
Miele, L.7
-
102
-
-
65249125270
-
Inhibition ofgamma-secretase activity inhibits tumor progression in a mousemodel of pancreatic ductal adenocarcinoma
-
Plentz, R.; Park J. S.; Rhim, A. D.; Abravanel, D.; Hezel, A. F.; Sharma, S. V.; Gurumurthy, S.; Deshpande, V.; Kenific, C.; Settleman, J.; Majumder, P. K.; Stanger, B. Z.; Bardeesy, N. Inhibition ofgamma-secretase activity inhibits tumor progression in a mousemodel of pancreatic ductal adenocarcinoma. Gastroenterology, 2009, 136, 1741-1749.
-
(2009)
Gastroenterology
, vol.136
, pp. 1741-1749
-
-
Plentz, R.1
Park, J.S.2
Rhim, A.D.3
Abravanel, D.4
Hezel, A.F.5
Sharma, S.V.6
Gurumurthy, S.7
Deshpande, V.8
Kenific, C.9
Settleman, J.10
Majumder, P.K.11
Stanger, B.Z.12
Bardeesy, N.13
-
103
-
-
33748872289
-
Down-regulation of Jagged-1 induces cell growth inhibition and Sphase arrest in prostate cancer cells
-
Zhang, Y.; Wang, Z.; Ahmed, F.; Banerjee, S.; Li, Y.; Sarkar, F. H. Down-regulation of Jagged-1 induces cell growth inhibition and Sphase arrest in prostate cancer cells. Int. J. Cancer, 2006, 119, 2071-2077.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 2071-2077
-
-
Zhang, Y.1
Wang, Z.2
Ahmed, F.3
Banerjee, S.4
Li, Y.5
Sarkar, F.H.6
-
104
-
-
33646877856
-
Notch-1down-regulation by curcumin is associated with the inhibition ofcell growth and the induction of apoptosis in pancreatic cancercells
-
Wang, Z.; Zhang, Y.; Banerjee, S.; Li, Y.; Sarkar, F. H. Notch-1down-regulation by curcumin is associated with the inhibition ofcell growth and the induction of apoptosis in pancreatic cancercells. Cancer, 2006, 106, 2503-2513.
-
(2006)
Cancer
, vol.106
, pp. 2503-2513
-
-
Wang, Z.1
Zhang, Y.2
Banerjee, S.3
Li, Y.4
Sarkar, F.H.5
-
105
-
-
33645064160
-
Inhibitionof nuclear factor kappab activity by genistein is mediated viaNotch-1 signaling pathway in pancreatic cancer cells
-
Wang, Z.; Zhang, Y.; Banerjee, S.; Li, Y.; Sarkar, F. H. Inhibitionof nuclear factor kappab activity by genistein is mediated viaNotch-1 signaling pathway in pancreatic cancer cells. Int. J. Cancer, 2006, 118, 1930-1936.
-
(2006)
Int. J. Cancer
, vol.118
, pp. 1930-1936
-
-
Wang, Z.1
Zhang, Y.2
Banerjee, S.3
Li, Y.4
Sarkar, F.H.5
-
106
-
-
35349009090
-
Resveratrol-induced apoptosisin human T-cell acute lymphoblastic leukaemia MOLT-4 cells
-
Cecchinato, V.; Chiaramonte, R.; Nizzardo, M.; Cristofaro, B.; Basile, A.; Sherbet, G. V.; Comi, P. Resveratrol-induced apoptosisin human T-cell acute lymphoblastic leukaemia MOLT-4 cells. Biochem. Pharmacol., 2007, 74, 1568-1574.
-
(2007)
Biochem. Pharmacol.
, vol.74
, pp. 1568-1574
-
-
Cecchinato, V.1
Chiaramonte, R.2
Nizzardo, M.3
Cristofaro, B.4
Basile, A.5
Sherbet, G.V.6
Comi, P.7
-
107
-
-
2342622022
-
Cancer chemopreventiveactivity of a mixture of Chinese herbs (antitumor B) in mouse lungtumor models
-
Zhang, Z.; Wang, Y.; Yao, R.; Li, J.; Yan, Y.; La, R. M.; Lemon, W. L.; Grubbs, C. J.; Lubet, R. A.; You, M. Cancer chemopreventiveactivity of a mixture of Chinese herbs (antitumor B) in mouse lungtumor models. Oncogene, 2004, 23, 3841-3850.
-
(2004)
Oncogene
, vol.23
, pp. 3841-3850
-
-
Zhang, Z.1
Wang, Y.2
Yao, R.3
Li, J.4
Yan, Y.5
La, R.M.6
Lemon, W.L.7
Grubbs, C.J.8
Lubet, R.A.9
You, M.10
|