Constitutive activation of Notch3 inhibits terminal epithelial differentiation in lungs of transgenic mice

Oncogene

Volumn 22, Issue 13, 2003, Pages 1988-1997

  Dang, Thao P ^a,b   Eichenberger, Shannon ^a   Gonzalez, Adriana ^a   Olson, Sandra ^a   Carbone, David P ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

Differentiation; Notch3; Pneumocytes; Transgenics

Indexed keywords

CELL MARKER; MEMBRANE RECEPTOR; NOTCH RECEPTOR; NOTCH3 RECEPTOR; SURFACTANT PROTEIN C; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; HYBRID PROTEIN; NOTCH3 PROTEIN, MOUSE; NOTCH4 PROTEIN, MOUSE; ONCOPROTEIN; SYNTHETIC DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; EMBRYO; ENHANCER REGION; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; LUNG ALVEOLUS CELL; LUNG CANCER; LUNG DEVELOPMENT; LUNG STRUCTURE; METAPLASIA; MOUSE; NEWBORN; NONHUMAN; PERINATAL MORTALITY; PRIORITY JOURNAL; PROMOTER REGION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; ADENOCARCINOMA; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; CELL TRANSFORMATION; CONGENITAL MALFORMATION; GENE EXPRESSION REGULATION; GENETICS; LETHAL GENE; LUNG; LUNG TUMOR; MORPHOGENESIS; PATHOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT; PROTEIN TERTIARY STRUCTURE;

ANIMALIA; INVERTEBRATA; MUS MUSCULUS; VERTEBRATA;

ADENOCARCINOMA; ANIMALS; CELL DIFFERENTIATION; CELL TRANSFORMATION, NEOPLASTIC; ENHANCER ELEMENTS (GENETICS); EPITHELIAL CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, LETHAL; GENES, SYNTHETIC; LUNG; LUNG NEOPLASMS; METAPLASIA; MICE; MICE, TRANSGENIC; MORPHOGENESIS; ORGAN SPECIFICITY; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; RECEPTORS, CELL SURFACE; RECEPTORS, NOTCH; RECOMBINANT FUSION PROTEINS;

EID: 0037417132     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206230     Document Type: Article

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