Notch signaling induces cell cycle arrest in small cell lung cancer cells

Cancer Research

Volumn 61, Issue 7, 2001, Pages 3200-3205

  Sriuranpong, Virote ^a   Borges, Michael W ^a   Ravi, Rajani K ^a   Arnold, Dagmar R ^a   Nelkin, Barry D ^a   Baylin, Stephen ^a   Ball, Douglas W ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; PROTEIN P21; PROTEIN P27;

ADENOVIRUS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE REPRESSION; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTO ONCOGENE; SIGNAL TRANSDUCTION; VIRUS RECOMBINANT;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARCINOMA, SMALL CELL; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; DNA-BINDING PROTEINS; ENZYME ACTIVATION; G1 PHASE; HELIX-LOOP-HELIX MOTIFS; HOMEODOMAIN PROTEINS; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE PROTEINS; RECEPTOR, NOTCH1; RECEPTOR, NOTCH2; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 0035300448     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Notch signaling: Cell fate control and signal integration in development
2. The ins and outs of notch signaling
3. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway
4. Notch signalling and the control of cell fate choices in vertebrates
5. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
6. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
7. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2
8. Inhibition of granulocytic differentiation by mNotch1
9. Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines
10. The human homolog of rat Jaggedl expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1
11. Cell-cycle arrest and apoptosis induced by Notch1 in B cells
12. Notch1 expression in early lymphopoiesis influences B versus T lineage determination
13. An achaete-scute homologue essential for neuroendocrine differentiation in the lung
14. Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary, epithelium
15. Constitutive achaete-scute homologue-1 promotes airway dysplasia and lung neuroendocrine tumors in transgenic mice
16. Conservation of the Drosophila lateral inhibition pathway in human lung cancer: A hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression
17. Activated Raf-1 causes growth arrest in human small-cell lung cancer cells
18. A simplified system for generating recombinant adenoviruses
19. Genomic cloning and chromosomal localization of HRY, the human homolog to the Drosophila segmentation gene, hairy
20. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
21. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines
22. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
23. Loss of the retinolastoma protein-related p130 protein in small cell lung carcinoma
24. NCI-Navy Medical Oncology Branch cell line data base
25. Raf-1 causes growth suppression and alteration of neuroendocrine markers in DMS53 human small-cell lung cancer cells
26. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
27. Interactions between Ras and Raf: Key regulatory proteins in cellular transformation
28. Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines
29. Differentiation of medullary, thyroid cancer by C-Raf-1 silences expression of the neural transcription factor human achaete-scute homolog-1
30. The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: A potential role for cellular raf kinases in neuronal growth factor signal transduction
31. Local induction of patterning and programmed cell death in the developing Drosophila retina
32. Notch inhibition of E47 supports the existence of a novel signaling pathway
33. Interplay of Notch and FGF signaling restricts cell fate and MAPK activation in the Drosophila trachea
34. Ras pathway signals are required for notch-mediated oncogenesis
35. A human homologue of the Drosophila developmental gene, Notch, is expressed in CD34+ hematopoietic precursors
36. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells
37. Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis
38. Maintenance of neuroepithelial progenitor cells by Δ-Notch signalling in the embryonic chick retina
39. The Notch/Jagged pathway inhibits proliferation of human hematopoietic progenitors in vitro
40. Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
41. Proneural gene self-stimulation in neural precursors: An essential mechanism for sense organ development that is regulated by Notch signaling
42. Hematopoietic stem cell quiescence maintained by p21cipl/wafl