메뉴 건너뛰기




Volumn 9, Issue 6, 2010, Pages 933-941

Comparing the yeast retrograde response and NF-κB stress responses: Implications for aging

Author keywords

Aging; NF B; Retrograde response; RTG; Stress

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TARGET OF RAPAMYCIN KINASE;

EID: 78249243079     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2010.00622.x     Document Type: Review
Times cited : (62)

References (106)
  • 1
  • 3
    • 0037038669 scopus 로고    scopus 로고
    • Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells
    • Amuthan G, Biswas G, Ananadatheerthavarada HK, Vijayasarathy C, Shephard HM, Avadhani NG (2002) Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells. Oncogene 21, 7839-7849.
    • (2002) Oncogene , vol.21 , pp. 7839-7849
    • Amuthan, G.1    Biswas, G.2    Ananadatheerthavarada, H.K.3    Vijayasarathy, C.4    Shephard, H.M.5    Avadhani, N.G.6
  • 4
    • 17444381939 scopus 로고    scopus 로고
    • Translocation carcinomas of the kidney
    • Argani P, Ladanyi M (2005) Translocation carcinomas of the kidney. Clin. Lab. Med. 25, 363-378.
    • (2005) Clin. Lab. Med. , vol.25 , pp. 363-378
    • Argani, P.1    Ladanyi, M.2
  • 5
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban RS, Nemoto S, Finkel T (2005) Mitochondria, oxidants, and aging. Cell 120, 483-495.
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 6
    • 0025309791 scopus 로고
    • Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?
    • Bandy B, Davison AJ (1990) Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? Free Radic. Biol. Med. 8, 523-539.
    • (1990) Free Radic. Biol. Med. , vol.8 , pp. 523-539
    • Bandy, B.1    Davison, A.J.2
  • 7
    • 9644262490 scopus 로고    scopus 로고
    • Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae
    • Barros MH, Bandy B, Tahara EB, Kowaltowski AJ (2004) Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae. J. Biol. Chem. 279, 49883-49888.
    • (2004) J. Biol. Chem. , vol.279 , pp. 49883-49888
    • Barros, M.H.1    Bandy, B.2    Tahara, E.B.3    Kowaltowski, A.J.4
  • 8
    • 0036811767 scopus 로고    scopus 로고
    • Identification of RTG2 as a modifier gene for CTG*CAG repeat instability in Saccharomyces cerevisiae
    • Bhattacharyya S, Rolfsmeier ML, Dixon MJ, Wagoner K, Lahue RS (2002) Identification of RTG2 as a modifier gene for CTG*CAG repeat instability in Saccharomyces cerevisiae. Genetics 162, 579-589.
    • (2002) Genetics , vol.162 , pp. 579-589
    • Bhattacharyya, S.1    Rolfsmeier, M.L.2    Dixon, M.J.3    Wagoner, K.4    Lahue, R.S.5
  • 9
    • 0033081478 scopus 로고    scopus 로고
    • Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk
    • Biswas G, Adebanjo OA, Freedman BD, Anandatheerthavarada HK, Vijayasarathy C, Zaidi M, Kotlikoff M, Avadhani NG (1999) Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk. EMBO J. 18, 522-533.
    • (1999) EMBO J. , vol.18 , pp. 522-533
    • Biswas, G.1    Adebanjo, O.A.2    Freedman, B.D.3    Anandatheerthavarada, H.K.4    Vijayasarathy, C.5    Zaidi, M.6    Kotlikoff, M.7    Avadhani, N.G.8
  • 10
    • 45549103879 scopus 로고    scopus 로고
    • A distinctive physiological role for IkappaBbeta in the propagation of mitochondrial respiratory stress signaling
    • Biswas G, Tang W, Sondheimer N, Guha M, Bansal S, Avadhani NG (2008) A distinctive physiological role for IkappaBbeta in the propagation of mitochondrial respiratory stress signaling. J. Biol. Chem. 283, 12586-12594.
    • (2008) J. Biol. Chem. , vol.283 , pp. 12586-12594
    • Biswas, G.1    Tang, W.2    Sondheimer, N.3    Guha, M.4    Bansal, S.5    Avadhani, N.G.6
  • 11
    • 1642270307 scopus 로고    scopus 로고
    • Rtg2 protein links metabolism and genome stability in yeast longevity
    • Borghouts C, Benguria A, Wawryn J, Jazwinski SM (2004) Rtg2 protein links metabolism and genome stability in yeast longevity. Genetics 166, 765-777.
    • (2004) Genetics , vol.166 , pp. 765-777
    • Borghouts, C.1    Benguria, A.2    Wawryn, J.3    Jazwinski, S.M.4
  • 12
    • 0035877820 scopus 로고    scopus 로고
    • Ikappa b-alpha, the NF-kappa B inhibitory subunit, interacts with ANT, the mitochondrial ATP/ADP translocator
    • Bottero V, Rossi F, Samson M, Mari M, Hofman P, Peyron JF (2001) Ikappa b-alpha, the NF-kappa B inhibitory subunit, interacts with ANT, the mitochondrial ATP/ADP translocator. J. Biol. Chem. 276, 21317-21324.
    • (2001) J. Biol. Chem. , vol.276 , pp. 21317-21324
    • Bottero, V.1    Rossi, F.2    Samson, M.3    Mari, M.4    Hofman, P.5    Peyron, J.F.6
  • 13
    • 1842665662 scopus 로고    scopus 로고
    • Mitochondrial signaling: the retrograde response
    • Butow RA, Avadhani NG (2004) Mitochondrial signaling: the retrograde response. Mol. Cell 14, 1-15.
    • (2004) Mol. Cell , vol.14 , pp. 1-15
    • Butow, R.A.1    Avadhani, N.G.2
  • 15
    • 66149087761 scopus 로고    scopus 로고
    • A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans
    • Cristina D, Cary M, Lunceford A, Clarke C, Kenyon C (2009) A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans. PLoS Genet. 5, e1000450.
    • (2009) PLoS Genet. , vol.5
    • Cristina, D.1    Cary, M.2    Lunceford, A.3    Clarke, C.4    Kenyon, C.5
  • 16
    • 44849117768 scopus 로고    scopus 로고
    • Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK
    • Dan HC, Cooper MJ, Cogswell PC, Duncan JA, Ting JP, Baldwin AS (2008) Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. Genes Dev. 22, 1490-1500.
    • (2008) Genes Dev. , vol.22 , pp. 1490-1500
    • Dan, H.C.1    Cooper, M.J.2    Cogswell, P.C.3    Duncan, J.A.4    Ting, J.P.5    Baldwin, A.S.6
  • 18
    • 41449106532 scopus 로고    scopus 로고
    • Target of rapamycin and LST8 proteins associate with membranes from the endoplasmic reticulum in the unicellular green alga Chlamydomonas reinhardtii
    • Diaz-Troya S, Florencio FJ, Crespo JL (2008) Target of rapamycin and LST8 proteins associate with membranes from the endoplasmic reticulum in the unicellular green alga Chlamydomonas reinhardtii. Eukaryot. Cell 7, 212-222.
    • (2008) Eukaryot. Cell , vol.7 , pp. 212-222
    • Diaz-Troya, S.1    Florencio, F.J.2    Crespo, J.L.3
  • 20
    • 8744281675 scopus 로고    scopus 로고
    • Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1.Rtg3p-dependent target genes
    • Dilova I, Aronova S, Chen JC, Powers T (2004) Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1.Rtg3p-dependent target genes. J. Biol. Chem. 279, 46527-46535.
    • (2004) J. Biol. Chem. , vol.279 , pp. 46527-46535
    • Dilova, I.1    Aronova, S.2    Chen, J.C.3    Powers, T.4
  • 21
  • 22
    • 0025302552 scopus 로고
    • Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter
    • Duyao MP, Buckler AJ, Sonenshein GE (1990a) Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter. Proc. Natl Acad. Sci. USA 87, 4727-4731.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 4727-4731
    • Duyao, M.P.1    Buckler, A.J.2    Sonenshein, G.E.3
  • 25
    • 39149084707 scopus 로고    scopus 로고
    • Elucidating the function of an ancient NF-kappaB p100 homologue, CrRelish, in antibacterial defense
    • Fan ZH, Wang XW, Lu J, Ho B, Ding JL (2008) Elucidating the function of an ancient NF-kappaB p100 homologue, CrRelish, in antibacterial defense. Infect. Immun. 76, 664-670.
    • (2008) Infect. Immun. , vol.76 , pp. 664-670
    • Fan, Z.H.1    Wang, X.W.2    Lu, J.3    Ho, B.4    Ding, J.L.5
  • 27
    • 23644431697 scopus 로고    scopus 로고
    • Interaction between Rtg2p and Mks1p in the regulation of the RTG pathway of Saccharomyces cerevisiae
    • Ferreira Junior JR, Spirek M, Liu Z, Butow RA (2005) Interaction between Rtg2p and Mks1p in the regulation of the RTG pathway of Saccharomyces cerevisiae. Gene 354, 2-8.
    • (2005) Gene , vol.354 , pp. 2-8
    • Ferreira Junior, J.R.1    Spirek, M.2    Liu, Z.3    Butow, R.A.4
  • 29
  • 30
    • 30044443639 scopus 로고    scopus 로고
    • Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression
    • Giannattasio S, Liu Z, Thornton J, Butow RA (2005) Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression. J. Biol. Chem. 280, 42528-42535.
    • (2005) J. Biol. Chem. , vol.280 , pp. 42528-42535
    • Giannattasio, S.1    Liu, Z.2    Thornton, J.3    Butow, R.A.4
  • 33
    • 78249260465 scopus 로고    scopus 로고
    • Jmol: an open-source java viewer for chemical structures in 3d, version 11.8. URL [accessed on 16 September 2010].
    • Hanson R (2008). Jmol: an open-source java viewer for chemical structures in 3d, version 11.8. URL [accessed on 16 September 2010].
    • (2008)
    • Hanson, R.1
  • 34
    • 77049308856 scopus 로고
    • Aging: a theory based on free radical and radiation chemistry
    • Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11, 298-300.
    • (1956) J. Gerontol. , vol.11 , pp. 298-300
    • Harman, D.1
  • 35
    • 0015319592 scopus 로고
    • The biologic clock: the mitochondria?
    • Harman D (1972) The biologic clock: the mitochondria? J. Am. Geriatr. Soc. 20, 145-147.
    • (1972) J. Am. Geriatr. Soc. , vol.20 , pp. 145-147
    • Harman, D.1
  • 36
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden MS, Ghosh S (2004) Signaling to NF-kappaB. Genes Dev. 18, 2195-2224.
    • (2004) Genes Dev. , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 37
    • 0033551701 scopus 로고    scopus 로고
    • Coordinate induction of energy gene expression in tissues of mitochondrial disease patients
    • Heddi A, Stepien G, Benke PJ, Wallace DC (1999) Coordinate induction of energy gene expression in tissues of mitochondrial disease patients. J. Biol. Chem. 274, 22968-22976.
    • (1999) J. Biol. Chem. , vol.274 , pp. 22968-22976
    • Heddi, A.1    Stepien, G.2    Benke, P.J.3    Wallace, D.C.4
  • 40
    • 1542285166 scopus 로고    scopus 로고
    • A genome-wide housekeeping role for TFIID and a highly regulated stress-related role for SAGA in Saccharomyces cerevisiae
    • Huisinga KL, Pugh BF (2004) A genome-wide housekeeping role for TFIID and a highly regulated stress-related role for SAGA in Saccharomyces cerevisiae. Mol. Cell 13, 573-585.
    • (2004) Mol. Cell , vol.13 , pp. 573-585
    • Huisinga, K.L.1    Pugh, B.F.2
  • 41
    • 33646006734 scopus 로고    scopus 로고
    • Signals from within: the DNA-damage-induced NF-kappaB response
    • Janssens S, Tschopp J (2006) Signals from within: the DNA-damage-induced NF-kappaB response. Cell Death Differ. 13, 773-784.
    • (2006) Cell Death Differ. , vol.13 , pp. 773-784
    • Janssens, S.1    Tschopp, J.2
  • 42
    • 0033941590 scopus 로고    scopus 로고
    • Metabolic control and gene dysregulation in yeast aging
    • Jazwinski SM (2000) Metabolic control and gene dysregulation in yeast aging. Ann. N Y Acad. Sci. 908, 21-30.
    • (2000) Ann. N Y Acad. Sci. , vol.908 , pp. 21-30
    • Jazwinski, S.M.1
  • 43
    • 23644443813 scopus 로고    scopus 로고
    • The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging
    • Jazwinski SM (2005) The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging. Gene 354, 22-27.
    • (2005) Gene , vol.354 , pp. 22-27
    • Jazwinski, S.M.1
  • 44
    • 0031027203 scopus 로고    scopus 로고
    • A basic helix-loop-helix-leucine zipper transcription complex in yeast functions in a signaling pathway from mitochondria to the nucleus
    • Jia Y, Rothermel B, Thornton J, Butow RA (1997a) A basic helix-loop-helix-leucine zipper transcription complex in yeast functions in a signaling pathway from mitochondria to the nucleus. Mol. Cell. Biol. 17, 1110-1117.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1110-1117
    • Jia, Y.1    Rothermel, B.2    Thornton, J.3    Butow, R.A.4
  • 45
    • 72149110062 scopus 로고    scopus 로고
    • Aup1-mediated regulation of Rtg3 during mitophagy
    • Journo D, Mor A, Abeliovich H (2009) Aup1-mediated regulation of Rtg3 during mitophagy. J. Biol. Chem. 284, 35885-35895.
    • (2009) J. Biol. Chem. , vol.284 , pp. 35885-35895
    • Journo, D.1    Mor, A.2    Abeliovich, H.3
  • 47
    • 0032831936 scopus 로고    scopus 로고
    • Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae
    • Kim S, Benguria A, Lai CY, Jazwinski SM (1999) Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. Mol. Biol. Cell 10, 3125-3136.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 3125-3136
    • Kim, S.1    Benguria, A.2    Lai, C.Y.3    Jazwinski, S.M.4
  • 48
    • 21644448873 scopus 로고    scopus 로고
    • The histone acetyltransferase GCN5 modulates the retrograde response and genome stability determining yeast longevity
    • Kim S, Ohkuni K, Couplan E, Jazwinski SM (2004) The histone acetyltransferase GCN5 modulates the retrograde response and genome stability determining yeast longevity. Biogerontology 5, 305-316.
    • (2004) Biogerontology , vol.5 , pp. 305-316
    • Kim, S.1    Ohkuni, K.2    Couplan, E.3    Jazwinski, S.M.4
  • 49
    • 52149108283 scopus 로고    scopus 로고
    • GbetaL regulates TNFalpha-induced NF-kappaB signaling by directly inhibiting the activation of IkappaB kinase
    • Kim YL, Kim JE, Shin KJ, Lee S, Ahn C, Chung J, Kim DH, Seong JY, Hwang JI (2008) GbetaL regulates TNFalpha-induced NF-kappaB signaling by directly inhibiting the activation of IkappaB kinase. Cell. Signal. 20, 2127-2133.
    • (2008) Cell. Signal. , vol.20 , pp. 2127-2133
    • Kim, Y.L.1    Kim, J.E.2    Shin, K.J.3    Lee, S.4    Ahn, C.5    Chung, J.6    Kim, D.H.7    Seong, J.Y.8    Hwang, J.I.9
  • 50
    • 0032947552 scopus 로고    scopus 로고
    • Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae
    • Kirchman PA, Kim S, Lai CY, Jazwinski SM (1999) Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae. Genetics 152, 179-190.
    • (1999) Genetics , vol.152 , pp. 179-190
    • Kirchman, P.A.1    Kim, S.2    Lai, C.Y.3    Jazwinski, S.M.4
  • 51
    • 33745470929 scopus 로고    scopus 로고
    • Robustness trade-offs and host-microbial symbiosis in the immune system
    • Kitano H, Oda K (2006) Robustness trade-offs and host-microbial symbiosis in the immune system. Mol. Syst. Biol. 2, 2006.0022.
    • (2006) Mol. Syst. Biol. , vol.2 , pp. 20060022
    • Kitano, H.1    Oda, K.2
  • 52
    • 0037093644 scopus 로고    scopus 로고
    • Increasing the precision of comparative models with YASARA NOVA-a self-parameterizing force field
    • Krieger E, Koraimann G, Vriend G (2002) Increasing the precision of comparative models with YASARA NOVA-a self-parameterizing force field. Proteins 47, 393-402.
    • (2002) Proteins , vol.47 , pp. 393-402
    • Krieger, E.1    Koraimann, G.2    Vriend, G.3
  • 53
    • 62349092245 scopus 로고    scopus 로고
    • Atypical pathways of NF-kappaB activation and aging
    • Kriete A, Mayo KL (2009) Atypical pathways of NF-kappaB activation and aging. Exp. Gerontol. 44, 250-255.
    • (2009) Exp. Gerontol. , vol.44 , pp. 250-255
    • Kriete, A.1    Mayo, K.L.2
  • 54
    • 48549099463 scopus 로고    scopus 로고
    • Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity
    • Kriete A, Mayo KL, Yalamanchili N, Beggs W, Bender P, Kari C, Rodeck U (2008) Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity. Immun. Ageing 5, 5.
    • (2008) Immun. Ageing , vol.5 , pp. 5
    • Kriete, A.1    Mayo, K.L.2    Yalamanchili, N.3    Beggs, W.4    Bender, P.5    Kari, C.6    Rodeck, U.7
  • 55
    • 77955476576 scopus 로고    scopus 로고
    • Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses
    • Kriete A, Bosl WJ, Booker G (2010) Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses. PLoS Comput. Biol. 6, e1000820.
    • (2010) PLoS Comput. Biol. , vol.6
    • Kriete, A.1    Bosl, W.J.2    Booker, G.3
  • 56
    • 0036743518 scopus 로고    scopus 로고
    • A mutation in the ATP2 gene abrogates the age asymmetry between mother and daughter cells of the yeast Saccharomyces cerevisiae
    • Lai CY, Jaruga E, Borghouts C, Jazwinski SM (2002) A mutation in the ATP2 gene abrogates the age asymmetry between mother and daughter cells of the yeast Saccharomyces cerevisiae. Genetics 162, 73-87.
    • (2002) Genetics , vol.162 , pp. 73-87
    • Lai, C.Y.1    Jaruga, E.2    Borghouts, C.3    Jazwinski, S.M.4
  • 57
    • 0037228016 scopus 로고    scopus 로고
    • A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
    • Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G (2003) A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat. Genet. 33, 40-48.
    • (2003) Nat. Genet. , vol.33 , pp. 40-48
    • Lee, S.S.1    Lee, R.Y.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Ruvkun, G.6
  • 58
    • 0033163393 scopus 로고    scopus 로고
    • Is NF-kappaB the sensor of oxidative stress?
    • Li N, Karin M (1999) Is NF-kappaB the sensor of oxidative stress? FASEB J. 13, 1137-1143.
    • (1999) FASEB J. , vol.13 , pp. 1137-1143
    • Li, N.1    Karin, M.2
  • 59
    • 68649100731 scopus 로고    scopus 로고
    • Epigenetic Control of MicroRNA Expression and Aging
    • Liang R, Bates DJ, Wang E (2009) Epigenetic Control of MicroRNA Expression and Aging. Curr. Genomics 10, 184-193.
    • (2009) Curr. Genomics , vol.10 , pp. 184-193
    • Liang, R.1    Bates, D.J.2    Wang, E.3
  • 60
    • 0027524176 scopus 로고
    • RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus
    • Liao X, Butow RA (1993) RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72, 61-71.
    • (1993) Cell , vol.72 , pp. 61-71
    • Liao, X.1    Butow, R.A.2
  • 61
    • 0037126596 scopus 로고    scopus 로고
    • RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p
    • Liu Z, Sekito T, Epstein CB, Butow RA (2001) RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p. EMBO J. 20, 7209-7219.
    • (2001) EMBO J. , vol.20 , pp. 7209-7219
    • Liu, Z.1    Sekito, T.2    Epstein, C.B.3    Butow, R.A.4
  • 62
    • 0141922982 scopus 로고    scopus 로고
    • Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p
    • Liu Z, Sekito T, Spirek M, Thornton J, Butow RA (2003) Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. Mol. Cell 12, 401-411.
    • (2003) Mol. Cell , vol.12 , pp. 401-411
    • Liu, Z.1    Sekito, T.2    Spirek, M.3    Thornton, J.4    Butow, R.A.5
  • 63
    • 26244451589 scopus 로고    scopus 로고
    • A novel degron-mediated degradation of the RTG pathway regulator, Mks1p, by SCFGrr1
    • Liu Z, Spirek M, Thornton J, Butow RA (2005) A novel degron-mediated degradation of the RTG pathway regulator, Mks1p, by SCFGrr1. Mol. Biol. Cell 16, 4893-4904.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4893-4904
    • Liu, Z.1    Spirek, M.2    Thornton, J.3    Butow, R.A.4
  • 64
    • 30044434360 scopus 로고    scopus 로고
    • The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations
    • Loeb LA, Wallace DC, Martin GM (2005) The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations. Proc. Natl Acad. Sci. USA 102, 18769-18770.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 18769-18770
    • Loeb, L.A.1    Wallace, D.C.2    Martin, G.M.3
  • 65
    • 33646156398 scopus 로고    scopus 로고
    • Age-related neural degeneration in nuclear-factor kappaB p50 knockout mice
    • Lu ZY, Yu SP, Wei JF, Wei L (2006) Age-related neural degeneration in nuclear-factor kappaB p50 knockout mice. Neuroscience 139, 965-978.
    • (2006) Neuroscience , vol.139 , pp. 965-978
    • Lu, Z.Y.1    Yu, S.P.2    Wei, J.F.3    Wei, L.4
  • 66
    • 0027276617 scopus 로고
    • Characterization of the MKS1 gene, a new negative regulator of the Ras-cyclic AMP pathway in Saccharomyces cerevisiae
    • Matsuura A, Anraku Y (1993) Characterization of the MKS1 gene, a new negative regulator of the Ras-cyclic AMP pathway in Saccharomyces cerevisiae. Mol. Gen. Genet. 238, 6-16.
    • (1993) Mol. Gen. Genet. , vol.238 , pp. 6-16
    • Matsuura, A.1    Anraku, Y.2
  • 67
    • 9244238708 scopus 로고    scopus 로고
    • Common and cell type-specific responses of human cells to mitochondrial dysfunction
    • Miceli MV, Jazwinski SM (2005a) Common and cell type-specific responses of human cells to mitochondrial dysfunction. Exp. Cell Res. 302, 270-280.
    • (2005) Exp. Cell Res. , vol.302 , pp. 270-280
    • Miceli, M.V.1    Jazwinski, S.M.2
  • 68
    • 20444483650 scopus 로고    scopus 로고
    • Nuclear gene expression changes due to mitochondrial dysfunction in ARPE-19 cells: implications for age-related macular degeneration
    • Miceli MV, Jazwinski SM (2005b) Nuclear gene expression changes due to mitochondrial dysfunction in ARPE-19 cells: implications for age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 46, 1765-1773.
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 1765-1773
    • Miceli, M.V.1    Jazwinski, S.M.2
  • 69
    • 0034641745 scopus 로고    scopus 로고
    • A genomewide survey of basic helix-loop-helix factors in Drosophila
    • Moore AW, Barbel S, Jan LY, Jan YN (2000) A genomewide survey of basic helix-loop-helix factors in Drosophila. Proc. Natl Acad. Sci. USA 97, 10436-10441.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 10436-10441
    • Moore, A.W.1    Barbel, S.2    Jan, L.Y.3    Jan, Y.N.4
  • 70
    • 0014991642 scopus 로고
    • Experiments on ageing in single cells of Saccharomyces cerevisiae
    • Muller I (1971) Experiments on ageing in single cells of Saccharomyces cerevisiae. Arch. Mikrobiol. 77, 20-25.
    • (1971) Arch. Mikrobiol. , vol.77 , pp. 20-25
    • Muller, I.1
  • 71
    • 33847059997 scopus 로고    scopus 로고
    • The mitochondrial energy transduction system and the aging process
    • Navarro A, Boveris A (2007) The mitochondrial energy transduction system and the aging process. Am. J. Physiol. Cell Physiol. 292, C670-C686.
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292
    • Navarro, A.1    Boveris, A.2
  • 72
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl HL (1999) Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18, 6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 73
    • 0029001576 scopus 로고
    • A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B
    • Pahl HL, Baeuerle PA (1995) A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B. EMBO J. 14, 2580-2588.
    • (1995) EMBO J. , vol.14 , pp. 2580-2588
    • Pahl, H.L.1    Baeuerle, P.A.2
  • 74
    • 0023106633 scopus 로고
    • The mitochondrial genotype can influence nuclear gene expression in yeast
    • Parikh VS, Morgan MM, Scott R, Clements LS, Butow RA (1987) The mitochondrial genotype can influence nuclear gene expression in yeast. Science 235, 576-580.
    • (1987) Science , vol.235 , pp. 576-580
    • Parikh, V.S.1    Morgan, M.M.2    Scott, R.3    Clements, L.S.4    Butow, R.A.5
  • 77
    • 0035853677 scopus 로고    scopus 로고
    • The Caenorhabditis elegans unc-32 gene encodes alternative forms of a vacuolar ATPase a subunit
    • Pujol N, Bonnerot C, Ewbank JJ, Kohara Y, Thierry-Mieg D (2001) The Caenorhabditis elegans unc-32 gene encodes alternative forms of a vacuolar ATPase a subunit. J. Biol. Chem. 276, 11913-11921.
    • (2001) J. Biol. Chem. , vol.276 , pp. 11913-11921
    • Pujol, N.1    Bonnerot, C.2    Ewbank, J.J.3    Kohara, Y.4    Thierry-Mieg, D.5
  • 78
    • 68749116494 scopus 로고    scopus 로고
    • Functional interaction of mTOR complexes in regulating mammalian cell size and cell cycle
    • Rosner M, Fuchs C, Siegel N, Valli A, Hengstschlager M (2009) Functional interaction of mTOR complexes in regulating mammalian cell size and cell cycle. Hum. Mol. Genet. 18, 3298-3310.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 3298-3310
    • Rosner, M.1    Fuchs, C.2    Siegel, N.3    Valli, A.4    Hengstschlager, M.5
  • 79
    • 57249083981 scopus 로고    scopus 로고
    • Integrated search and alignment of protein structures
    • Sacan A, Toroslu IH, Ferhatosmanoglu H (2008) Integrated search and alignment of protein structures. Bioinformatics 24, 2872-2879.
    • (2008) Bioinformatics , vol.24 , pp. 2872-2879
    • Sacan, A.1    Toroslu, I.H.2    Ferhatosmanoglu, H.3
  • 80
    • 0142026429 scopus 로고    scopus 로고
    • Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae
    • Sakaki K, Tashiro K, Kuhara S, Mihara K (2003) Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae. J. Biochem. 134, 373-384.
    • (2003) J. Biochem. , vol.134 , pp. 373-384
    • Sakaki, K.1    Tashiro, K.2    Kuhara, S.3    Mihara, K.4
  • 81
    • 40949123149 scopus 로고    scopus 로고
    • Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
    • Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T (2008a) Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res. Rev. 7, 83-105.
    • (2008) Ageing Res. Rev. , vol.7 , pp. 83-105
    • Salminen, A.1    Huuskonen, J.2    Ojala, J.3    Kauppinen, A.4    Kaarniranta, K.5    Suuronen, T.6
  • 82
    • 42449142360 scopus 로고    scopus 로고
    • Interaction of aging-associated signaling cascades: inhibition of NF-kappaB signaling by longevity factors FoxOs and SIRT1
    • Salminen A, Ojala J, Huuskonen J, Kauppinen A, Suuronen T, Kaarniranta K (2008b) Interaction of aging-associated signaling cascades: inhibition of NF-kappaB signaling by longevity factors FoxOs and SIRT1. Cell. Mol. Life Sci. 65, 1049-1058.
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 1049-1058
    • Salminen, A.1    Ojala, J.2    Huuskonen, J.3    Kauppinen, A.4    Suuronen, T.5    Kaarniranta, K.6
  • 83
    • 33745458797 scopus 로고    scopus 로고
    • MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis
    • Sans CL, Satterwhite DJ, Stoltzman CA, Breen KT, Ayer DE (2006) MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis. Mol. Cell. Biol. 26, 4863-4871.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 4863-4871
    • Sans, C.L.1    Satterwhite, D.J.2    Stoltzman, C.A.3    Breen, K.T.4    Ayer, D.E.5
  • 84
    • 33748752151 scopus 로고    scopus 로고
    • The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity
    • Schieke SM, Phillips D, McCoy Jr JP, Aponte AM, Shen RF, Balaban RS, Finkel T (2006) The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity. J. Biol. Chem. 281, 27643-27652.
    • (2006) J. Biol. Chem. , vol.281 , pp. 27643-27652
    • Schieke, S.M.1    Phillips, D.2    McCoy Jr, J.P.3    Aponte, A.M.4    Shen, R.F.5    Balaban, R.S.6    Finkel, T.7
  • 85
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth
    • Schmelzle T, Hall MN (2000) TOR, a central controller of cell growth. Cell 103, 253-262.
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 86
    • 0036623358 scopus 로고    scopus 로고
    • Cytokine regulation of pro- and anti-apoptotic genes in rat hepatocytes: NF-kappaB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents apoptosis
    • Schoemaker MH, Ros JE, Homan M, Trautwein C, Liston P, Poelstra K, Van Goor H, Jansen PL, Moshage H (2002) Cytokine regulation of pro- and anti-apoptotic genes in rat hepatocytes: NF-kappaB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents apoptosis. J. Hepatol. 36, 742-750.
    • (2002) J. Hepatol. , vol.36 , pp. 742-750
    • Schoemaker, M.H.1    Ros, J.E.2    Homan, M.3    Trautwein, C.4    Liston, P.5    Poelstra, K.6    Van Goor, H.7    Jansen, P.L.8    Moshage, H.9
  • 87
    • 0034046342 scopus 로고    scopus 로고
    • Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p
    • Sekito T, Thornton J, Butow RA (2000) Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol. Biol. Cell 11, 2103-2115.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 2103-2115
    • Sekito, T.1    Thornton, J.2    Butow, R.A.3
  • 88
    • 0036200999 scopus 로고    scopus 로고
    • RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]
    • Sekito T, Liu Z, Thornton J, Butow RA (2002) RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol. Biol. Cell 13, 795-804.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 795-804
    • Sekito, T.1    Liu, Z.2    Thornton, J.3    Butow, R.A.4
  • 89
    • 0032534475 scopus 로고    scopus 로고
    • Role of RAS2 in recovery from chronic stress: effect on yeast life span
    • Shama S, Kirchman PA, Jiang JC, Jazwinski SM (1998) Role of RAS2 in recovery from chronic stress: effect on yeast life span. Exp. Cell Res. 245, 368-378.
    • (1998) Exp. Cell Res. , vol.245 , pp. 368-378
    • Shama, S.1    Kirchman, P.A.2    Jiang, J.C.3    Jazwinski, S.M.4
  • 90
    • 0031459980 scopus 로고    scopus 로고
    • Extrachromosomal rDNA circles-a cause of aging in yeast
    • Sinclair DA, Guarente L (1997) Extrachromosomal rDNA circles-a cause of aging in yeast. Cell 91, 1033-1042.
    • (1997) Cell , vol.91 , pp. 1033-1042
    • Sinclair, D.A.1    Guarente, L.2
  • 91
    • 0030828307 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappa B in an animal model of aging
    • Spencer NF, Poynter ME, Im SY, Daynes RA (1997) Constitutive activation of NF-kappa B in an animal model of aging. Int. Immunol. 9, 1581-1588.
    • (1997) Int. Immunol. , vol.9 , pp. 1581-1588
    • Spencer, N.F.1    Poynter, M.E.2    Im, S.Y.3    Daynes, R.A.4
  • 92
    • 10944234560 scopus 로고    scopus 로고
    • Melanocytes and the microphthalmia transcription factor network
    • Steingrimsson E, Copeland NG, Jenkins NA (2004) Melanocytes and the microphthalmia transcription factor network. Annu. Rev. Genet. 38, 365-411.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 365-411
    • Steingrimsson, E.1    Copeland, N.G.2    Jenkins, N.A.3
  • 93
    • 44349149476 scopus 로고    scopus 로고
    • Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression
    • Stoltzman CA, Peterson CW, Breen KT, Muoio DM, Billin AN, Ayer DE (2008) Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. Proc. Natl Acad. Sci. USA 105, 6912-6917.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 6912-6917
    • Stoltzman, C.A.1    Peterson, C.W.2    Breen, K.T.3    Muoio, D.M.4    Billin, A.N.5    Ayer, D.E.6
  • 94
    • 77953419714 scopus 로고    scopus 로고
    • Regulation of YY1 in tumorigenesis and its targeting potential in cancer therapy
    • Sui G (2009) Regulation of YY1 in tumorigenesis and its targeting potential in cancer therapy. Mol. Cell. Pharmacol. 1, 157-176.
    • (2009) Mol. Cell. Pharmacol. , vol.1 , pp. 157-176
    • Sui, G.1
  • 95
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ, Baltimore D (2006) NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl. Acad. Sci. USA 103, 12481-12486.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 96
    • 10644288528 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha induces NADPH oxidase activity in macrophages, leading to the generation of LDL with PPAR-alpha activation properties
    • Teissier E, Nohara A, Chinetti G, Paumelle R, Cariou B, Fruchart JC, Brandes RP, Shah A, Staels B (2004) Peroxisome proliferator-activated receptor alpha induces NADPH oxidase activity in macrophages, leading to the generation of LDL with PPAR-alpha activation properties. Circ. Res. 95, 1174-1182.
    • (2004) Circ. Res. , vol.95 , pp. 1174-1182
    • Teissier, E.1    Nohara, A.2    Chinetti, G.3    Paumelle, R.4    Cariou, B.5    Fruchart, J.C.6    Brandes, R.P.7    Shah, A.8    Staels, B.9
  • 98
    • 0028803718 scopus 로고
    • The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans
    • Vanfleteren JR, De Vreese A (1995) The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans. FASEB J. 9, 1355-1361.
    • (1995) FASEB J. , vol.9 , pp. 1355-1361
    • Vanfleteren, J.R.1    De Vreese, A.2
  • 99
    • 0036845841 scopus 로고    scopus 로고
    • Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide
    • Wang S, Kotamraju S, Konorev E, Kalivendi S, Joseph J, Kalyanaraman B (2002) Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide. Biochem. J. 367, 729-740.
    • (2002) Biochem. J. , vol.367 , pp. 729-740
    • Wang, S.1    Kotamraju, S.2    Konorev, E.3    Kalivendi, S.4    Joseph, J.5    Kalyanaraman, B.6
  • 100
    • 61449125103 scopus 로고    scopus 로고
    • HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells
    • Wang L, Li H, Zhang Y, Santella RM, Weinstein IB (2009) HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells. Int. J. Cancer 124, 1526-1534.
    • (2009) Int. J. Cancer , vol.124 , pp. 1526-1534
    • Wang, L.1    Li, H.2    Zhang, Y.3    Santella, R.M.4    Weinstein, I.B.5
  • 101
    • 77953362421 scopus 로고    scopus 로고
    • Gene regulatory changes in yeast during life extension by nutrient limitation
    • Wang J, Jiang JC, Jazwinski SM (2010) Gene regulatory changes in yeast during life extension by nutrient limitation. Exp. Gerontol. 45, 621-631.
    • (2010) Exp. Gerontol. , vol.45 , pp. 621-631
    • Wang, J.1    Jiang, J.C.2    Jazwinski, S.M.3
  • 103
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S, Loewith R, Hall MN (2006) TOR signaling in growth and metabolism. Cell 124, 471-484.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 104
    • 0032588841 scopus 로고    scopus 로고
    • An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta
    • Xu Y, Kiningham KK, Devalaraja MN, Yeh CC, Majima H, Kasarskis EJ, St Clair DK (1999) An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta. DNA Cell Biol. 18, 709-722.
    • (1999) DNA Cell Biol. , vol.18 , pp. 709-722
    • Xu, Y.1    Kiningham, K.K.2    Devalaraja, M.N.3    Yeh, C.C.4    Majima, H.5    Kasarskis, E.J.6    St Clair, D.K.7
  • 105
    • 77956241785 scopus 로고    scopus 로고
    • Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans
    • Yang W, Hekimi S (2010) Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans. Aging Cell 9, 433-447.
    • (2010) Aging Cell , vol.9 , pp. 433-447
    • Yang, W.1    Hekimi, S.2
  • 106
    • 39449115394 scopus 로고    scopus 로고
    • I-TASSER server for protein 3D structure prediction
    • Zhang Y (2008) I-TASSER server for protein 3D structure prediction. BMC Bioinformatics 9, 40.
    • (2008) BMC Bioinformatics , vol.9 , pp. 40
    • Zhang, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.