The histone acetyltransferase GCN5 modulates the retrograde response and genome stability determining yeast longevity

Biogerontology

Volumn 5, Issue 5, 2004, Pages 305-316

  Kim, Sangkyu ^a   Ohkuni, Kentaro ^a   Couplan, Elodie ^a   Jazwinski, S Michal ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Chromatin; Genome stability; Histone acetylases; Retrograde response; Transcriptional coactivators; Transcriptional silencing

Indexed keywords

HISTONE ACETYLTRANSFERASE GCN5; RIBOSOME DNA; DNA BINDING PROTEIN; GCN5 PROTEIN, S CEREVISIAE; HISTONE ACETYLTRANSFERASE; PRIMER DNA; PROTEIN KINASE; SACCHAROMYCES CEREVISIAE PROTEIN;

ACETYLATION; ARTICLE; CHROMATIN; EPIGENETICS; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE LOCUS; GENE REPLICATION; GENE SILENCING; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; HETEROCHROMATIN; LIFESPAN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SACCHAROMYCES CEREVISIAE; STRESS; YEAST; GENETICS; GENOME; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BASE SEQUENCE; DNA PRIMERS; DNA-BINDING PROTEINS; GENE SILENCING; GENOME, FUNGAL; HISTONE ACETYLTRANSFERASES; PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 21644448873     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-004-2568-x     Document Type: Article

References (59)

1. Allsopp R, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, Greider CW and Harley CB (1992) Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 89: 10114-10118
2. Borghouts C, Benguria A, Wawryn J and Jazwinski SM (2004) Rtg2 protein links metabolism and genome stability in yeast longevity. Genetics 166: 765-777
3. Braunstein M, Rose AB, Holmes SG, Allis CD and Broach JR (1993) Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev 7: 592-604
4. Braunstein M, Sobel RE, Allis CD, Turner BM and Broach JR (1996) Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern. Mol Cell Biol 16: 4349-4356
5. Brownell JE and Allis CD (1996) Special HATs for special occasions: linking acetylation to chromatin assembly and gene activation. Curr Opin Genet Dev 6: 176-184
6. Brownell JE, Zhou J, Ranalli T, Kobayashi R, Edmondson DG, Roth SY and Allis CD (1996) Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84: 843-851
7. Bryk M, Briggs SD, Strahl BD, Curcio MJ, Allis CD and Winston F (2002) Evidence that Set1, a factor required for methylation of histone H3, regulates rDNA silencing in S. cerevisiae in a Sir2-independent mechanism. Curr Biol 12: 165-170
8. Butow RA (2002) Cellular responses to mitochondrial dysfunction: it's not always downhill. Cell Growth Differen 9: 1043-1045
9. Carrozza MJ, Utley RT, Workman JL and Côté J (2003) The diverse functions of histone acetyltransferase complexes. Trends Genet 19: 321-329
10. Chiang YC, Komarnitsky P, Chase D and Denis CL (1996) ADR1 activation domains contact the histone acetyltransferase GCN5 and the core transcriptional factor TFIIB. J Biol Chem 271: 32359-32365
11. Collier JJ, Doan T-TT, Daniels MC, Schurr JR, Kolls JK and Scott DK (2003) c-Myc is required for the glucose-mediated induction of metabolic enzyme genes. J Biol Chem 278: 6588-6595
12. Cost GJ and Boeke JD (1996) A useful colony colour phenotype associated with the yeast selectable/counterselectable marker MET15. Yeast 12: 939-941
13. D'mello NP and Jazwinski SM (1991) Telomere length constancy during aging of Saccharomyces cerevisiae. J Bacteriol 173: 6709-6713
14. Durrin LK, Mann RK, Kayne PS and Grunstein M (1991) Yeast histone H4 N-terminal sequence is required for promoter activation in vivo. Cell 65: 1023-1031
15. Epstein CB, Walker JA, Hale W, Davé V, Thornton J, Macatee TL, Garner HR and Butow RA (2001) Genome-wide responses to mitochondrial dysfunction. Mol Biol Cell 12: 297-308
16. Feng J, Funks WD, Wang S-S, Weinrich SL, Avilion AA, Chiu C-P, Adams RR, Chang E, Allsopp RC, Tu J, Le S, West MD, Harley CB, Andrews WH, Greider CW and Villeponteau B (1995) The RNA component of human telomerase. Science 269: 1236-1241
17. Georgakopoulos T and Thireos G (1992) Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription. EMBO J 11: 4145-4152
18. Gottschling DE, Aparicio OM, Billington BL and Zakian VA (1990) Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63: 751-762
19. Grunstein M (1997) Histone acetylation in chromatin structure and transcription. Nature 389: 349-352
20. Harley CB (1991) Telomere loss: mitotic clock or genetic time bomb? Mutat Res 256: 271-282
21. Harley CB, Futcher AB and Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345: 458-460
22. Hecht A, Laroche T, Strahl-Bolsinger S, Gasser SM and Grunstein M (1995) Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80: 583-592
23. Hecht A, Strahl-Bolsinger S and Grunstein M (1996) Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature 383: 92-96
24. Huisinga KL and Pugh BF (2004) A genome-wide housekeeping role for TFIID and a highly regulated stress-related role for SAGA in Saccharomyces cerevisiae. Mol Cell 13: 573-585
25. Jazwinski SM (1990) An experimental system for the molecular analysis of the aging process: the budding yeast Saccharomyces cerevisiae. J Gerontol 45: B68-B74
26. Jazwinski SM (1996) Longevity, genes, and aging. Science 273: 54-59
27. Jazwinski SM (2000) Metabolic control and gene dysregulation in yeast aging. Ann NY Acad Sci 908: 21-30
28. Jazwinski SM (2003) Mitochondria, metabolism, and aging in yeast. In: Nyström T and Osiewacz HD (eds) Model Systems in Aging, pp 39-59. Springer, Berlin
29. Jenuwein T and Allis CD (2001) Translating the histone code. Science 293: 1074-1080
30. Jiang JC, Jaruga E, Repnevskaya MV and Jazwinski SM (September 8, 2000) An intervention resembling caloric restriction prolongs life span and retards aging in yeast. FASEB J 10.1096/fj.00-242fje
31. Jiang JC, Wawryn J, Shantha Kumara HMC and Jazwinski SM (2002) Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast. Exp Gerontol 37: 1023-1030
32. Jiang YW and Stillman DJ (1996) Epigenetic effects on yeast transcription caused by mutations in an actin-related protein present in the nucleus. Genes Dev 10: 604-619
33. Kaeberlein M, McVey M and Guarente L (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 13: 2570-2580
34. Kim S, Villeponteau B and Jazwinski SM (1996) Effect of replicative age on transcriptional silencing near telomeres in Saccharomyces cerevisie. Biochem Biophy Res Comm 219: 370-376
35. Kim S, Kirchman PA, Benguria A and Jazwinski SM (1998) Experimentation with the yeast model. In: Yu BP (ed) Methods in Aging Research, pp 191-213. CRC Press, Boca Raton
36. Kim S, Benguria A, Lai C-Y and Jazwinski SM (1999) Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. Mol Biol Cell 10: 3125-3136
37. Kirchman PA, Kim S, Lai C-Y and Jazwinski SM (1999) Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae. Genetics 152: 179-190
38. Lai C-Y, Jaruga E, Borghouts C and Jazwinski SM (2002) A mutation in the ATP2 gene abrogates the age asymmetry between mother and daughter cells of the yeast Saccharomyces cerevisiae. Genetics 162: 73-87
39. Laurenson P and Rine J (1992) Silencers, silencing, and heritable transcriptional states. Microbiol Rev 56: 543-560
40. Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR and Guarente L (2002) Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418: 344-348
41. Loo S and Rine J (1995) Silencing and heritable domains of gene expression. Annu Rev Cell Dev Biol 11: 519-548
42. McMahon SB, Wood MA and Cole MD (2000) The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc. Mol Cell Biol 20: 556-562
43. Mortimer RK and Johnston JR (1959) Life span of individual yeast cells. Nature 183: 1751-1752
44. Müller I, Zimmermann M, Becker D and Flömer M (1980) Calendar life span versus budding life span of Saccharomyces cerevisiae. Mech Ageing Dev 12: 47-52
45. Peterson CL and Workman JL (2000) Promoter targeting and chromatin remodeling by the SWI/SNF complex. Curr Opin Genet Dev 10: 187-192
46. Pray-Grant MG, Shieltz D, McMahon SJ, Wood JM, Kennedy EL, Cook RG, Workman JL, Yates JR and Grant PA (2002) The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway. Mol Cell Biol 22: 8774-8786
47. Rose MD, Winston F and Hieter P (1990) Methods in Yeast Genetics. A Laboratory Course Mannual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
48. Roth SY, Denu JM and Allis CD (2001) Histone acetyltransferases. Annu Rev Biochem 70: 81-120
49. Ruiz-Carrillo A, Wangh LJ and Allfrey V (1975) Processing of newly synthesized histone molecules. Science 190: 117-128
50. Schmitt ME, Brown TA and Trumpower BL (1990) A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucl Acids Res 18: 3091-3092
51. Sikorski RS and Hieter P (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27
52. Simon M, Adam G, Rapatz W, Spevak W and Ruis H (1991) The Saccharomyces cerevisiae ADR1 gene is a positive regulator of transcription of genes encoding peroxisomal proteins. Mol Cell Biol 11: 699-704
53. Sinclair DA and Guarente L (1997) Extrachromosomal rDNA circles-a cause of aging in yeast. Cell 91: 1033-1042
54. Smeal T, Claus J, Kennedy B, Cole F and Guarente L (1996) Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae. Cell 84: 633-642
55. Smith JS and Boeke JD (1997) An unusual form of transcriptional silencing in yeast ribosomal DNA. Genes Dev 11: 241-254
56. Struhl K (1998) Histone acetylation and transcriptional regulatory mechanisms. Genes Dev 12: 599-606
57. Sussel L, Vannier D and Shore D (1995) Suppressors of defective silencing in yeast: Effects on transcriptional repression at the HMR locus, cell growth and telomere structure. Genetics 141: 873-888
58. Vogelauer M, Wu J, Suka N and Grunstein M (2000) Global histone acetylation and deacetylation in yeast. Nature 408: 495-498
59. Workman JL and Kingston RE (1998) Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu Rev Biochem 67: 545-579