Matched sizes of activating and inhibitory receptor ligand pairs are required for optimal signal integration by human natural killer cells

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Köhler, Karsten ^a,d   Xiong, Shiqiu ^b,d   Brzostek, Joanna ^a   Mehrabi, Maryam ^a   Eissmann, Philipp ^a   Harrison, Alice ^b   Cordoba, Shaun Paul ^b   Oddos, Stephane ^a   Miloserdov, Vladimir ^c   Gould, Keith ^a   Burroughs, Nigel J ^c   van der Merwe, Philip Anton ^b   Davis, Daniel M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF WARWICK   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; HLA C ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; NATURAL KILLER CELL RECEPTOR NKG2D; PROTEIN MICA; UNCLASSIFIED DRUG; HLA ANTIGEN CLASS 1; HYBRID PROTEIN; KIR2DL1 PROTEIN, HUMAN; KLRK1 PROTEIN, HUMAN; LIGAND; MHC CLASS I RELATED CHAIN A; MHC CLASS I-RELATED CHAIN A; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; PHOTOPROTEIN;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL CONTACT; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; LYMPHOCYTE ACTIVATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PROTEIN BINDING; PROTEIN LOCALIZATION; RNA TRANSLATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; CELL LINE; CONFOCAL MICROSCOPY; GENETICS; METABOLISM; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; CELL LINE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA-C ANTIGENS; HUMANS; KILLER CELLS, NATURAL; LIGANDS; LUMINESCENT PROTEINS; LYMPHOCYTE ACTIVATION; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PROTEIN BINDING; RECEPTORS, KIR2DL1; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 78149489327     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015374     Document Type: Article

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