CD107a as a functional marker for the identification of natural killer cell activity

Journal of Immunological Methods

Volumn 294, Issue 1-2, 2004, Pages 15-22

  Alter, Galit ^a   Malenfant, Jessica M ^a   Altfeld, Marcus ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

CD107a; Cytotoxicity; Degranulation; IFN ; Natural Killer Cells; TNF

Indexed keywords

BIOLOGICAL MARKER; CYTOKINE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE RELEASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYSIS; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANTIGENS, CD; BIOLOGICAL MARKERS; CELL DEGRANULATION; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; HISTOCOMPATIBILITY ANTIGENS; HUMANS; K562 CELLS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; T-LYMPHOCYTES, CYTOTOXIC; UP-REGULATION;

EID: 10344255635     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2004.08.008     Document Type: Article

References (15)

1. + T cells by a flow cytometric assay for degranulation J. Immunol. Methods 2003 65
2. J.K. Burkhardt, S. Hester, and Y. Argon Two proteins targeted to the same lytic granule compartment undergo very different posttranslational processing Proc. Natl. Acad. Sci. U. S. A. 1989 7128
3. A. Cerwenka, and L.L. Lanier Ligands for natural killer cell receptors: redundancy or specificity Immunol. Rev. 2001 158
4. M.A. Cooper, T.A. Fehniger, and M.A. Caligiuri The biology of human natural killer-cell subsets Trends Immunol. 2001 633
5. S.S. Farag, J.B. VanDeusen, T.A. Fehniger, and M.A. Caligiuri Biology and clinical impact of human natural killer cells Int. J. Hematol. 2003 7
6. A.R. French, and W.M. Yokoyama Natural killer cells and viral infections Curr. Opin. Immunol. 2003 45
7. M. Fukuda Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking J. Biol. Chem. 1991 21327
8. K. Kannan, R.M. Stewart, W. Bounds, S.R. Carlsson, M. Fukuda, K.W. Betzing, and R.F. Holcombe Lysosome-associated membrane proteins h-LAMP1 (CD107a) and h-LAMP2 (CD107b) are activation-dependent cell surface glycoproteins in human peripheral blood mononuclear cells which mediate cell adhesion to vascular endothelium Cell. Immunol. 1996 10
9. R. Kiessling, E. Klein, and H. Wigzell Natural killer cells in the mouse. I: cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype Eur. J. Immunol. 1975 112
10. A. Moretta, C. Bottino, M.C. Mingari, R. Biassoni, and L. Moretta What is a natural killer cell? Nat. Immunol. 2002 6
11. P.J. Peters, J. Borst, V. Oorschot, M. Fukuda, O. Krahenbuhl, J. Tschopp, J.W. Slot, and H.J. Geuze Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes J. Exp. Med. 1991 1099
12. V. Rubio, T.B. Stuge, N. Singh, M.R. Betts, J.S. Weber, M. Roederer, and P.P. Lee Ex vivo identification, isolation and analysis of tumor-cytolytic T cells Nat. Med. 2003 1377
13. J. Tschopp, and M. Nabholz Perforin-mediated target cell lysis by cytolytic T lymphocytes Annu. Rev. Immunol. 1990 279
14. B.G. Winchester Lysosomal membrane proteins Eur. J. Paediatr. Neurol. 2001 11
15. W.M. Yokoyama, and A.A. Scalzo Natural killer cell activation receptors in innate immunity to infection Microbes Infect. 2002 1513