The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1

Nature Immunology

Volumn 9, Issue 3, 2008, Pages 245-253

  Venuprasad, K ^a   Huang, Haining ^a   Harada, Yousuke ^a   Elly, Chris ^a   Subramaniam, Malayannan ^b   Spelsberg, Thomas ^b   Su, Jin ^a   Liu, Yun Cai ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA INDUCIBLE EARLY GENE 1 PRODUCT; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE ITCH; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONJUGATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; IMMUNE RESPONSE; IMMUNOREGULATION; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; RESPIRATORY TRACT INFLAMMATION;

ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EARLY GROWTH RESPONSE TRANSCRIPTION FACTORS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HYPERSENSITIVITY; INFLAMMATION; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REPRESSOR PROTEINS; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION; TH2 CELLS; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES;

EID: 39449083806     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1564     Document Type: Article

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