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Volumn 23, Issue 6, 2003, Pages 1946-1960

Activation of the early B-cell-specific mb-1 (Ig-α) gene by Pax-5 is dependent on an unmethylated Ets binding site

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN MB 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR PAX5; UNCLASSIFIED DRUG;

EID: 0037370442     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.6.1946-1960.2003     Document Type: Article
Times cited : (90)

References (46)
  • 1
    • 0026698147 scopus 로고
    • Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis
    • Adams, B., P. Dorfler, A. Aguzzi, Z. Kozmik, P. Urbanek, I. Maurer-Fogy, and M. Busslinger. 1992. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev. 6:1589-1607.
    • (1992) Genes Dev. , vol.6 , pp. 1589-1607
    • Adams, B.1    Dorfler, P.2    Aguzzi, A.3    Kozmik, Z.4    Urbanek, P.5    Maurer-Fogy, I.6    Busslinger, M.7
  • 2
    • 0033601073 scopus 로고    scopus 로고
    • Methylation-induced repression - Belts, braces and chromatin
    • Bird, A. P., and A. P. Wolffe. 1999. Methylation-induced repression - belts, braces and chromatin. Cell 99:451-454.
    • (1999) Cell , vol.99 , pp. 451-454
    • Bird, A.P.1    Wolffe, A.P.2
  • 3
    • 0025187182 scopus 로고
    • Protective methylation of immunoglobulin and T cell receptor (TcR) gene loci prior to induction of class switch and TcR recombination
    • Burger, C., and A. Radbruch. 1990. Protective methylation of immunoglobulin and T cell receptor (TcR) gene loci prior to induction of class switch and TcR recombination. Eur. J. Immunol. 20:2285-2291.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 2285-2291
    • Burger, C.1    Radbruch, A.2
  • 4
    • 0036607452 scopus 로고    scopus 로고
    • DNA methyl-transferases get connected to chromatin
    • Burgers, W. A., F. Fuks, and T. Kouzarides. 2002. DNA methyltransferases get connected to chromatin. Trends Genet. 18:275-277.
    • (2002) Trends Genet. , vol.18 , pp. 275-277
    • Burgers, W.A.1    Fuks, F.2    Kouzarides, T.3
  • 5
    • 0029099805 scopus 로고
    • The role of BSAP (Pax-5) in B-cell development
    • Busslinger, M., and P. Urbanek. 1995. The role of BSAP (Pax-5) in B-cell development. Curr. Opin. Genet. Dev. 5:595-601.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 595-601
    • Busslinger, M.1    Urbanek, P.2
  • 6
    • 0034682539 scopus 로고    scopus 로고
    • V(D)J recombination is not activated by demethylation of the kappa locus
    • Cherry, S. R., C. Beard, R. Jaenisch, and D. Baltimore. 2000. V(D)J recombination is not activated by demethylation of the kappa locus. Proc. Natl. Acad. Sci. USA 97:8467-8472.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8467-8472
    • Cherry, S.R.1    Beard, C.2    Jaenisch, R.3    Baltimore, D.4
  • 7
    • 0028315867 scopus 로고
    • Role of DNA methylation in the regulation of transcription
    • Eden, S., and H. Cedar. 1994. Role of DNA methylation in the regulation of transcription. Curr. Opin. Genet. Dev. 4:255-259.
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 255-259
    • Eden, S.1    Cedar, H.2
  • 9
    • 0037013153 scopus 로고    scopus 로고
    • Specificity of gene regulation
    • Emerson, B. A. 2002. Specificity of gene regulation. Cell 109:267-270.
    • (2002) Cell , vol.109 , pp. 267-270
    • Emerson, B.A.1
  • 10
    • 0027396509 scopus 로고
    • Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate
    • Engler, P., A. Weng, and U. Storb. 1993. Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate. Mol. Cell. Biol. 13:571-577.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 571-577
    • Engler, P.1    Weng, A.2    Storb, U.3
  • 11
    • 0026562759 scopus 로고
    • BlyF, a novel cell-type- and stage-specific regulator of the B-lymphocyte gene mb-1
    • Feldhaus, A., D. Mbangkollo, K. Arvin, C. Klug, and H. Singh. 1992. BlyF, a novel cell-type- and stage-specific regulator of the B-lymphocyte gene mb-1. Mol. Cell. Biol. 12:1126-1133.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1126-1133
    • Feldhaus, A.1    Mbangkollo, D.2    Arvin, K.3    Klug, C.4    Singh, H.5
  • 12
    • 0029833870 scopus 로고    scopus 로고
    • Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter
    • Fitzsimmons, D., W. Hodsdon, W. Wheat, S. M. Maira, B. Wasylyk, and J. Hagman. 1996. Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter. Genes Dev. 10:2198-2211.
    • (1996) Genes Dev. , vol.10 , pp. 2198-2211
    • Fitzsimmons, D.1    Hodsdon, W.2    Wheat, W.3    Maira, S.M.4    Wasylyk, B.5    Hagman, J.6
  • 13
    • 0035886477 scopus 로고    scopus 로고
    • Highly conserved amino acids in Pax and Ets proteins are required for DNA binding and ternary complex assembly
    • Fitzsimmons, D., R. Lutz, W. Wheat, H. M. Chamberlin, and J. Hagman. 2001. Highly conserved amino acids in Pax and Ets proteins are required for DNA binding and ternary complex assembly. Nucleic Acids Res. 29:4154-4165.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4154-4165
    • Fitzsimmons, D.1    Lutz, R.2    Wheat, W.3    Chamberlin, H.M.4    Hagman, J.5
  • 14
    • 0035697276 scopus 로고    scopus 로고
    • Structural studies of Ets-1/Pax5 complex formation on DNA
    • Garvie, C. W., J. Hagman, and C. Wolberger. 2001. Structural studies of Ets-1/Pax5 complex formation on DNA. Mol. Cell 8:1267-1276.
    • (2001) Mol. Cell , vol.8 , pp. 1267-1276
    • Garvie, C.W.1    Hagman, J.2    Wolberger, C.3
  • 15
    • 0028932663 scopus 로고
    • CpG methylation has differential effects on the binding of YY-1 and ETS proteins to the bi-directional promoter of the Surf-1 and Surf-2 genes
    • Gaston, K., and M. Fried. 1995. CpG methylation has differential effects on the binding of YY-1 and ETS proteins to the bi-directional promoter of the Surf-1 and Surf-2 genes. Nucleic Acids Res. 23:901-909.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 901-909
    • Gaston, K.1    Fried, M.2
  • 16
    • 0030738231 scopus 로고    scopus 로고
    • Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (MS-SNuPE)
    • Gonzalgo, M. L., and P. A. Jones. 1997. Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (MS-SNuPE). Nucleic Acids Res. 25:2529-2531.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2529-2531
    • Gonzalgo, M.L.1    Jones, P.A.2
  • 17
    • 0027301927 scopus 로고
    • Methylation status of immunoglobulin kappa gene segments correlates with their recombination potential
    • Goodhardt, M., P. Cavelier, N. Doyen, S. Kallenbach, C. Babinet, and F. Rougeon. 1993. Methylation status of immunoglobulin kappa gene segments correlates with their recombination potential. Eur. J. Immunol. 23:1789-1795.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1789-1795
    • Goodhardt, M.1    Cavelier, P.2    Doyen, N.3    Kallenbach, S.4    Babinet, C.5    Rougeon, F.6
  • 18
    • 0028283946 scopus 로고
    • Structure, chromosomal localization, and methylation pattern of the human mb-1 gene
    • Ha, H., B. L. Barnoski, L. Sun, B. S. Emanuel, and P. D. Burrows. 1994. Structure, chromosomal localization, and methylation pattern of the human mb-1 gene. J. Immunol. 152:5749-5757.
    • (1994) J. Immunol. , vol.152 , pp. 5749-5757
    • Ha, H.1    Barnoski, B.L.2    Sun, L.3    Emanuel, B.S.4    Burrows, P.D.5
  • 19
    • 0027229972 scopus 로고
    • Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression
    • Hagman, J., C. Belanger, A. Travis, C. W. Turck, and R. Grosschedl. 1993. Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression. Genes Dev. 7:760-773.
    • (1993) Genes Dev. , vol.7 , pp. 760-773
    • Hagman, J.1    Belanger, C.2    Travis, A.3    Turck, C.W.4    Grosschedl, R.5
  • 20
    • 0026730324 scopus 로고
    • An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene
    • Hagman, J., and R. Grosschedl. 1992. An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene. Proc. Natl. Acad. Sci. USA 89:8889-8893.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8889-8893
    • Hagman, J.1    Grosschedl, R.2
  • 21
    • 0029076534 scopus 로고
    • EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains
    • Hagman, J., M. J. Gutch, H. Lin, and R. Grosschedl. 1995. EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains. EMBO J. 14:2907-2916.
    • (1995) EMBO J. , vol.14 , pp. 2907-2916
    • Hagman, J.1    Gutch, M.J.2    Lin, H.3    Grosschedl, R.4
  • 22
    • 0026006396 scopus 로고
    • A novel lineage-specific nuclear factor regulates mb-1 gene transcription at the early stages of B cell differentiation
    • Hagman, J., A. Travis, and R. Grosschedl. 1991. A novel lineage-specific nuclear factor regulates mb-1 gene transcription at the early stages of B cell differentiation. EMBO J. 10:3409-3417.
    • (1991) EMBO J. , vol.10 , pp. 3409-3417
    • Hagman, J.1    Travis, A.2    Grosschedl, R.3
  • 23
    • 0024121584 scopus 로고
    • Cytosine methylation does not affect binding of transcription factor Sp1
    • Harrington, M. A., P. A. Jones, M. Imagawa, and M. Karin. 1988. Cytosine methylation does not affect binding of transcription factor Sp1. Proc. Natl. Acad. Sci. USA 85:2066-2070.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2066-2070
    • Harrington, M.A.1    Jones, P.A.2    Imagawa, M.3    Karin, M.4
  • 24
    • 0028385758 scopus 로고
    • Versatile retroviral vectors for potential use in gene therapy
    • Hawley, R. G., F. H. Lieu, A. Z. Fong, and T. S. Hawley. 1994. Versatile retroviral vectors for potential use in gene therapy. Gene Ther. 1:136-138.
    • (1994) Gene Ther. , vol.1 , pp. 136-138
    • Hawley, R.G.1    Lieu, F.H.2    Fong, A.Z.3    Hawley, T.S.4
  • 25
    • 0024114728 scopus 로고
    • A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells
    • Hombach, J., L. Leclercq, A. Radbruch, K. Rajewsky, and M. Reth. 1988. A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells. EMBO J. 7:3451-3456.
    • (1988) EMBO J. , vol.7 , pp. 3451-3456
    • Hombach, J.1    Leclercq, L.2    Radbruch, A.3    Rajewsky, K.4    Reth, M.5
  • 26
    • 0025068716 scopus 로고
    • Molecular components of the B-cell antigen receptor complex of the IgM class
    • Hombach, J., T. Tsubata, L. Leclerq, H. Stappert, and M. Reth. 1990. Molecular components of the B-cell antigen receptor complex of the IgM class. Nature 343:760-762.
    • (1990) Nature , vol.343 , pp. 760-762
    • Hombach, J.1    Tsubata, T.2    Leclerq, L.3    Stappert, H.4    Reth, M.5
  • 27
    • 0032937871 scopus 로고    scopus 로고
    • Evidence that protein binding specifies sites of DNA demethylation
    • Hsieh, C.-L. 1999. Evidence that protein binding specifies sites of DNA demethylation. Mol. Cell. Biol. 19:46-56.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 46-56
    • Hsieh, C.-L.1
  • 28
    • 0027076298 scopus 로고
    • Replication, transcription. CpG methylation and DNA topology in V(D)J recombination
    • Hsieh, C. L., G. Gauss, and M. R. Lieber. 1992. Replication, transcription, CpG methylation and DNA topology in V(D)J recombination. Curr. Top. Microbiol. Immunol. 182:125-135.
    • (1992) Curr. Top. Microbiol. Immunol. , vol.182 , pp. 125-135
    • Hsieh, C.L.1    Gauss, G.2    Lieber, M.R.3
  • 30
    • 0023883436 scopus 로고
    • A colostral protein that induces the growth and differentiation of resting B lymphocytes
    • Julius, M. H., M. Janusz, and J. Lisowski. 1988. A colostral protein that induces the growth and differentiation of resting B lymphocytes. J. Immunol. 140:1366-1371.
    • (1988) J. Immunol. , vol.140 , pp. 1366-1371
    • Julius, M.H.1    Janusz, M.2    Lisowski, J.3
  • 31
    • 0026710736 scopus 로고
    • The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP
    • Kozmik, Z., S. Wang, P. Dorfler, B. Adams, and M. Busslinger. 1992. The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP. Mol. Cell. Biol. 12:2662-2672.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2662-2672
    • Kozmik, Z.1    Wang, S.2    Dorfler, P.3    Adams, B.4    Busslinger, M.5
  • 32
    • 0036279221 scopus 로고    scopus 로고
    • Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene
    • Lee, D. U., S. Agarwal, and A. Rao. 2002. Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene. Immunity 16:649-660.
    • (2002) Immunity , vol.16 , pp. 649-660
    • Lee, D.U.1    Agarwal, S.2    Rao, A.3
  • 34
    • 0034703717 scopus 로고    scopus 로고
    • Transcription factor dosage affects changes in higher order chromatin structure associated with activation of a heterochromatic gene
    • Lundgren, M., C. Chow, P. Sabbattini, A. Georgiou, S. Minaee, and N. Dillon. 2000. Transcription factor dosage affects changes in higher order chromatin structure associated with activation of a heterochromatic gene. Cell 103:733-743.
    • (2000) Cell , vol.103 , pp. 733-743
    • Lundgren, M.1    Chow, C.2    Sabbattini, P.3    Georgiou, A.4    Minaee, S.5    Dillon, N.6
  • 35
    • 0013449584 scopus 로고    scopus 로고
    • Roles of EBF and Pax-5 in B lineage commitment and development
    • Maier, H., and J. Hagman. 2002. Roles of EBF and Pax-5 in B lineage commitment and development. Semin. Immunol. 14:415-422.
    • (2002) Semin. Immunol. , vol.14 , pp. 415-422
    • Maier, H.1    Hagman, J.2
  • 36
    • 0034599971 scopus 로고    scopus 로고
    • Antigen-specific B cell memory: Expression and replenishment of a novel B220-memory B cell compartment
    • McHeyzer-Williams, L. J., M. Cool, and M. G. McHeyzer-Williams. 2000. Antigen-specific B cell memory: expression and replenishment of a novel B220-memory B cell compartment. J. Exp. Med. 191:1149-1165.
    • (2000) J. Exp. Med. , vol.191 , pp. 1149-1165
    • McHeyzer-Williams, L.J.1    Cool, M.2    McHeyzer-Williams, M.G.3
  • 37
    • 0029955714 scopus 로고    scopus 로고
    • The pCL vector system: Rapid production of helper-free, high-titer, recombinant retroviruses
    • Naviaux, R. K., E. Constanzi, M. Haas, and I. M. Verma. 1996. The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses. J. Virol. 70:5701-5705.
    • (1996) J. Virol. , vol.70 , pp. 5701-5705
    • Naviaux, R.K.1    Constanzi, E.2    Haas, M.3    Verma, I.M.4
  • 38
    • 0032522538 scopus 로고    scopus 로고
    • Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments
    • Nutt, S. L., A. M. Morrison, P. Dorfler, A. Rolink, and M. Busslinger. 1998. Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments. EMBO J. 17:2319-2333.
    • (1998) EMBO J. , vol.17 , pp. 2319-2333
    • Nutt, S.L.1    Morrison, A.M.2    Dorfler, P.3    Rolink, A.4    Busslinger, M.5
  • 39
    • 0036247031 scopus 로고    scopus 로고
    • Methylation matters: Modeling a manageable genome
    • Ordway, J. M., and T. Curran. 2002. Methylation matters: modeling a manageable genome. Cell Growth Differ. 13:149-162.
    • (2002) Cell Growth Differ , vol.13 , pp. 149-162
    • Ordway, J.M.1    Curran, T.2
  • 40
    • 0030052190 scopus 로고    scopus 로고
    • Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1
    • Reimold, A. M., P. D. Ponath, Y. S. Li, R. R. Hardy, C. S. David, J. L. Strominger, and L. H. Glimcher. 1996. Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1. J. Exp. Med. 183:393-401.
    • (1996) J. Exp. Med. , vol.183 , pp. 393-401
    • Reimold, A.M.1    Ponath, P.D.2    Li, Y.S.3    Hardy, R.R.4    David, C.S.5    Strominger, J.L.6    Glimcher, L.H.7
  • 41
    • 0036798665 scopus 로고    scopus 로고
    • Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene
    • Schebesta, M., P. Pfeffer, and M. Busslinger. 2002. Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene. Immunity 17:781-793.
    • (2002) Immunity , vol.17 , pp. 781-793
    • Schebesta, M.1    Pfeffer, P.2    Busslinger, M.3
  • 42
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with "mini-extracts," prepared from a small number of cells
    • Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with "mini-extracts," prepared from a small number of cells. Nucleic Acids Res. 17:6419.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 44
    • 0013417354 scopus 로고    scopus 로고
    • Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems, unit 10.17C
    • J. E. Coligan et al. (ed.), John Wiley and Sons, Inc., Hoboken, N.J.
    • Swift, S., J. B. Lorens, P. Achacoso, and G. P. Nolan. 2002. Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems, unit 10.17C. In J. E. Coligan et al. (ed.), Current protocols in immunology. John Wiley and Sons, Inc., Hoboken, N.J.
    • (2002) Current Protocols in Immunology
    • Swift, S.1    Lorens, J.B.2    Achacoso, P.3    Nolan, G.P.4
  • 45
    • 0035962668 scopus 로고    scopus 로고
    • Methyl CpG binding proteins: Coupling chromatin architecture to gene regulation
    • Wade, P. A. 2001. Methyl CpG binding proteins: coupling chromatin architecture to gene regulation. Oncogene 20:3166-3173.
    • (2001) Oncogene , vol.20 , pp. 3166-3173
    • Wade, P.A.1
  • 46
    • 0033049571 scopus 로고    scopus 로고
    • The highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes
    • Wheat, W., D. Fitzsimmons, H. Lennox, S. R. Krautkramer, L. N. Gentile, L. P. McIntosh, and J. Hagman. 1999. The highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes. Mol. Cell. Biol. 19:2231-2241.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2231-2241
    • Wheat, W.1    Fitzsimmons, D.2    Lennox, H.3    Krautkramer, S.R.4    Gentile, L.N.5    McIntosh, L.P.6    Hagman, J.7


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