-
1
-
-
0000429264
-
Neurotrophin trafficking by anterograde transport
-
Altar CA, DiStefano PS (1998) Neurotrophin trafficking by anterograde transport. Trends Neurosci 21:433-437.
-
(1998)
Trends Neurosci
, vol.21
, pp. 433-437
-
-
Altar, C.A.1
DiStefano, P.S.2
-
2
-
-
1842334441
-
Anterograde transport of brain-derived neurotrophic factor and its role in the brain
-
Altar CA, Cai N, Bliven T, Juhasz M, Conner JM, Acheson AL, Lindsay RM, Wiegand SJ (1997) Anterograde transport of brain-derived neurotrophic factor and its role in the brain. Nature 389:856-860.
-
(1997)
Nature
, vol.389
, pp. 856-860
-
-
Altar, C.A.1
Cai, N.2
Bliven, T.3
Juhasz, M.4
Conner, J.M.5
Acheson, A.L.6
Lindsay, R.M.7
Wiegand, S.J.8
-
3
-
-
46149100739
-
Distinct role of long 3′ UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons
-
An JJ, Gharami K, Liao GY, Woo NH, Lau AG, Vanevski F, Torre ER, Jones KR, Feng Y, Lu B, Xu B (2008) Distinct role of long 3′ UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell 134:175-187.
-
(2008)
Cell
, vol.134
, pp. 175-187
-
-
An, J.J.1
Gharami, K.2
Liao, G.Y.3
Woo, N.H.4
Lau, A.G.5
Vanevski, F.6
Torre, E.R.7
Jones, K.R.8
Feng, Y.9
Lu, B.10
Xu, B.11
-
4
-
-
17844372504
-
From mRNP trafficking to spine dysmorphogenesis: The roots of fragile X syndrome
-
Bagni C, Greenough WT (2005) From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat Rev Neurosci 6:376-387.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 376-387
-
-
Bagni, C.1
Greenough, W.T.2
-
5
-
-
2442506955
-
Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor
-
Baquet ZC, Gorski JA, Jones KR (2004) Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor. J Neurosci 24:4250-4258.
-
(2004)
J Neurosci
, vol.24
, pp. 4250-4258
-
-
Baquet, Z.C.1
Gorski, J.A.2
Jones, K.R.3
-
6
-
-
27744573047
-
The seizure-related phenotype of brain-derived neurotrophic factor knockdown mice
-
Barton ME, Shannon HE (2005) The seizure-related phenotype of brain-derived neurotrophic factor knockdown mice. Neuroscience 136:563-569.
-
(2005)
Neuroscience
, vol.136
, pp. 563-569
-
-
Barton, M.E.1
Shannon, H.E.2
-
7
-
-
34250171705
-
Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington's disease
-
Benn CL, Slow EJ, Farrell LA, Graham R, Deng Y, Hayden MR, Cha JH (2007) Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington's disease. Neuroscience 147:354-372.
-
(2007)
Neuroscience
, vol.147
, pp. 354-372
-
-
Benn, C.L.1
Slow, E.J.2
Farrell, L.A.3
Graham, R.4
Deng, Y.5
Hayden, M.R.6
Cha, J.H.7
-
8
-
-
4444350918
-
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease
-
Canals JM, Pineda JR, Torres-Peraza JF, Bosch M, Martín- Ibañez R, Muñoz MT, Mengod G, Ernfors P, Alberch J (2004) Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease. J Neurosci 24:7727-7739.
-
(2004)
J Neurosci
, vol.24
, pp. 7727-7739
-
-
Canals, J.M.1
Pineda, J.R.2
Torres-Peraza, J.F.3
Bosch, M.4
Martín- Ibañez, R.5
Muñoz, M.T.6
Mengod, G.7
Ernfors, P.8
Alberch, J.9
-
9
-
-
34948855498
-
Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease
-
Cho SR, Benraiss A, Chmielnicki E, Samdani A, Economides A, Goldman SA (2007) Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease. J Clin Invest 117:2889-2902.
-
(2007)
J Clin Invest
, vol.117
, pp. 2889-2902
-
-
Cho, S.R.1
Benraiss, A.2
Chmielnicki, E.3
Samdani, A.4
Economides, A.5
Goldman, S.A.6
-
10
-
-
18444379677
-
Akt is altered in an animal model of Huntington's disease and in patients
-
Colin E, Régulier E, Perrin V, Dürr A, Brice A, Aebischer P, Déglon N, Humbert S, Saudou F (2005) Akt is altered in an animal model of Huntington's disease and in patients. Eur J Neurosci 21:1478-1488.
-
(2005)
Eur J Neurosci
, vol.21
, pp. 1478-1488
-
-
Colin, E.1
Régulier, E.2
Perrin, V.3
Dürr, A.4
Brice, A.5
Aebischer, P.6
Déglon, N.7
Humbert, S.8
Saudou, F.9
-
11
-
-
0032765275
-
Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex
-
Croll SD, Suri C, Compton DL, Simmons MV, Yancopoulos GD, Lindsay RM, Wiegand SJ, Rudge JS, Scharfman HE (1999) Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience 93:1491-1506.
-
(1999)
Neuroscience
, vol.93
, pp. 1491-1506
-
-
Croll, S.D.1
Suri, C.2
Compton, D.L.3
Simmons, M.V.4
Yancopoulos, G.D.5
Lindsay, R.M.6
Wiegand, S.J.7
Rudge, J.S.8
Scharfman, H.E.9
-
12
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Davies SW, Turmaine M, Cozens BA, DiFiglia M, Sharp AH, Ross CA, Scherzinger E, Wanker EE, Mangiarini L, Bates GP (1997) Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell 90:537-548.
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
DiFiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
13
-
-
0026320986
-
Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: A combined study using the section-Golgi method and calbindin D28k immunocytochemistry
-
Ferrante RJ, Kowall NW, Richardson EP Jr (1991) Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry. J Neurosci 11:3877-3887.
-
(1991)
J Neurosci
, vol.11
, pp. 3877-3887
-
-
Ferrante, R.J.1
Kowall, N.W.2
Richardson Jr., E.P.3
-
14
-
-
0034595722
-
Brain-derived neurotrophic factor in Huntington disease
-
Ferrer I, Goutan E, Marín C, Rey MJ, Ribalta T (2000) Brain-derived neurotrophic factor in Huntington disease. Brain Res 866:257-261.
-
(2000)
Brain Res
, vol.866
, pp. 257-261
-
-
Ferrer, I.1
Goutan, E.2
Marín, C.3
Rey, M.J.4
Ribalta, T.5
-
15
-
-
0030967339
-
Intact mirror-tracing and impaired rotary-pursuit skill learning in patients with Huntington's disease: Evidence for dissociable memory systems in skill learning
-
Gabrieli JD, Stebbins GT, Singh J, Willingham DB, Goetz CG (1997) Intact mirror-tracing and impaired rotary-pursuit skill learning in patients with Huntington's disease: evidence for dissociable memory systems in skill learning. Neuropsychology 11:272-281.
-
(1997)
Neuropsychology
, vol.11
, pp. 272-281
-
-
Gabrieli, J.D.1
Stebbins, G.T.2
Singh, J.3
Willingham, D.B.4
Goetz, C.G.5
-
16
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
Gauthier LR, Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F (2004) Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118:127-138.
-
(2004)
Cell
, vol.118
, pp. 127-138
-
-
Gauthier, L.R.1
Charrin, B.C.2
Borrell-Pagès, M.3
Dompierre, J.P.4
Rangone, H.5
Cordelières, F.P.6
De Mey, J.7
MacDonald, M.E.8
Lessmann, V.9
Humbert, S.10
Saudou, F.11
-
17
-
-
41749083721
-
Brain-derived neurotrophic factor overexpression in the forebrain ameliorates Huntington's disease phenotypes in mice
-
Gharami K, Xie Y, An JJ, Tonegawa S, Xu B (2008) Brain-derived neurotrophic factor overexpression in the forebrain ameliorates Huntington's disease phenotypes in mice. J Neurochem 105:369-379.
-
(2008)
J Neurochem
, vol.105
, pp. 369-379
-
-
Gharami, K.1
Xie, Y.2
An, J.J.3
Tonegawa, S.4
Xu, B.5
-
18
-
-
0346749473
-
Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells
-
Gines S, Ivanova E, Seong IS, Saura CA, MacDonald ME (2003) Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells. J Biol Chem 278:50514-50522.
-
(2003)
J Biol Chem
, vol.278
, pp. 50514-50522
-
-
Gines, S.1
Ivanova, E.2
Seong, I.S.3
Saura, C.A.4
MacDonald, M.E.5
-
19
-
-
60349130539
-
Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: Involvement of phospholipase C gamma activity and glutamate receptor expression
-
Giralt A, Rodrigo T, Martin ED, Gonzalez JR, Milà M, Ceña V, Dierssen M, Canals JM, Alberch J (2009) Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipase C gamma activity and glutamate receptor expression. Neuroscience 158:1234-1250.
-
(2009)
Neuroscience
, vol.158
, pp. 1234-1250
-
-
Giralt, A.1
Rodrigo, T.2
Martin, E.D.3
Gonzalez, J.R.4
Milà, M.5
Ceña, V.6
Dierssen, M.7
Canals, J.M.8
Alberch, J.9
-
20
-
-
0021982117
-
Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease
-
Graveland GA, Williams RS, DiFiglia M (1985) Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease. Science 227:770-773.
-
(1985)
Science
, vol.227
, pp. 770-773
-
-
Graveland, G.A.1
Williams, R.S.2
DiFiglia, M.3
-
21
-
-
0024503945
-
Neuropsychological evidence for multiple implicit memory systems: A comparison of Alzheimer's, Huntington's, and Parkinson's disease patients
-
Heindel WC, Salmon DP, Shults CW, Walicke PA, Butters N (1989) Neuropsychological evidence for multiple implicit memory systems: a comparison of Alzheimer's, Huntington's, and Parkinson's disease patients. J Neurosci 9:582-587.
-
(1989)
J Neurosci
, vol.9
, pp. 582-587
-
-
Heindel, W.C.1
Salmon, D.P.2
Shults, C.W.3
Walicke, P.A.4
Butters, N.5
-
22
-
-
58149385090
-
Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin
-
Her LS, Goldstein LS (2008) Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin. J Neurosci 28:13662-13672.
-
(2008)
J Neurosci
, vol.28
, pp. 13662-13672
-
-
Her, L.S.1
Goldstein, L.S.2
-
23
-
-
0033578688
-
BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex
-
Huang ZJ, Kirkwood A, Pizzorusso T, Porciatti V, Morales B, Bear MF, Maffei L, Tonegawa S (1999) BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex. Cell 98:739-755.
-
(1999)
Cell
, vol.98
, pp. 739-755
-
-
Huang, Z.J.1
Kirkwood, A.2
Pizzorusso, T.3
Porciatti, V.4
Morales, B.5
Bear, M.F.6
Maffei, L.7
Tonegawa, S.8
-
24
-
-
0033168977
-
Expression of the striatal DARPP-32/ARPP-21 phenotype in GABAergic neurons requires neurotrophins in vivo and in vitro
-
Ivkovic S, Ehrlich ME (1999) Expression of the striatal DARPP-32/ARPP-21 phenotype in GABAergic neurons requires neurotrophins in vivo and in vitro. J Neurosci 19:5409-5419.
-
(1999)
J Neurosci
, vol.19
, pp. 5409-5419
-
-
Ivkovic, S.1
Ehrlich, M.E.2
-
25
-
-
13244279632
-
Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons
-
Ji Y, Pang PT, Feng L, Lu B (2005) Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons. Nat Neurosci 8:164-172.
-
(2005)
Nat Neurosci
, vol.8
, pp. 164-172
-
-
Ji, Y.1
Pang, P.T.2
Feng, L.3
Lu, B.4
-
26
-
-
0025727341
-
Procedural learning is impaired in Huntington's disease: Evidence from the serial reaction time task
-
Knopman D, Nissen MJ (1991) Procedural learning is impaired in Huntington's disease: evidence from the serial reaction time task. Neuropsychologia 29:245-254.
-
(1991)
Neuropsychologia
, vol.29
, pp. 245-254
-
-
Knopman, D.1
Nissen, M.J.2
-
27
-
-
0029160413
-
Suppressed epileptogenesis in BDNF mutant mice
-
Kokaia M, Ernfors P, Kokaia Z, Elmér E, Jaenisch R, Lindvall O (1995) Suppressed epileptogenesis in BDNF mutant mice. Exp Neurol 133:215-224.
-
(1995)
Exp Neurol
, vol.133
, pp. 215-224
-
-
Kokaia, M.1
Ernfors, P.2
Kokaia, Z.3
Elmér, E.4
Jaenisch, R.5
Lindvall, O.6
-
28
-
-
18744409324
-
Decreased BDNF signalling in transgenic mice reduces epileptogenesis
-
Lähteinen S, Pitkänen A, Saarelainen T, Nissinen J, Koponen E, Castrén E (2002) Decreased BDNF signalling in transgenic mice reduces epileptogenesis. Eur J Neurosci 15:721-734.
-
(2002)
Eur J Neurosci
, vol.15
, pp. 721-734
-
-
Lähteinen, S.1
Pitkänen, A.2
Saarelainen, T.3
Nissinen, J.4
Koponen, E.5
Castrén, E.6
-
29
-
-
67651183756
-
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2
-
Liu J, Tang TS, Tu H, Nelson O, Herndon E, Huynh DP, Pulst SM, Bezprozvanny I (2009) Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2. J Neurosci 29:9148-9162.
-
(2009)
J Neurosci
, vol.29
, pp. 9148-9162
-
-
Liu, J.1
Tang, T.S.2
Tu, H.3
Nelson, O.4
Herndon, E.5
Huynh, D.P.6
Pulst, S.M.7
Bezprozvanny, I.8
-
30
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L, Sathasivam K, Seller M, Cozens B, Harper A, Hetherington C, Lawton M, Trottier Y, Lehrach H, Davies SW, Bates GP (1996) Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87:493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
31
-
-
38649128208
-
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF
-
Matsumoto T, Rauskolb S, Polack M, Klose J, Kolbeck R, Korte M, Barde YA (2008) Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat Neurosci 11:131-133.
-
(2008)
Nat Neurosci
, vol.11
, pp. 131-133
-
-
Matsumoto, T.1
Rauskolb, S.2
Polack, M.3
Klose, J.4
Kolbeck, R.5
Korte, M.6
Barde, Y.A.7
-
32
-
-
0028040712
-
Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons
-
Mizuno K, Carnahan J, Nawa H (1994) Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons. Dev Biol 165:243-256.
-
(1994)
Dev Biol
, vol.165
, pp. 243-256
-
-
Mizuno, K.1
Carnahan, J.2
Nawa, H.3
-
33
-
-
33745979171
-
Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice
-
Pang TY, Stam NC, Nithianantharajah J, Howard ML, Hannan AJ (2006) Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice. Neuroscience 141:569-584.
-
(2006)
Neuroscience
, vol.141
, pp. 569-584
-
-
Pang, T.Y.1
Stam, N.C.2
Nithianantharajah, J.3
Howard, M.L.4
Hannan, A.J.5
-
34
-
-
39249084415
-
The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model
-
Peng Q, Masuda N, Jiang M, Li Q, Zhao M, Ross CA, Duan W (2008) The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model. Exp Neurol 210:154-163.
-
(2008)
Exp Neurol
, vol.210
, pp. 154-163
-
-
Peng, Q.1
Masuda, N.2
Jiang, M.3
Li, Q.4
Zhao, M.5
Ross, C.A.6
Duan, W.7
-
35
-
-
20144379127
-
Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease
-
Pineda JR, Canals JM, Bosch M, Adell A, Mengod G, Artigas F, Ernfors P, Alberch J (2005) Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease. J Neurochem 93:1057-1068.
-
(2005)
J Neurochem
, vol.93
, pp. 1057-1068
-
-
Pineda, J.R.1
Canals, J.M.2
Bosch, M.3
Adell, A.4
Mengod, G.5
Artigas, F.6
Ernfors, P.7
Alberch, J.8
-
36
-
-
33749010358
-
Neurotrophin-regulated signalling pathways
-
Reichardt LF (2006) Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci 361:1545-1564.
-
(2006)
Philos Trans R Soc Lond B Biol Sci
, vol.361
, pp. 1545-1564
-
-
Reichardt, L.F.1
-
37
-
-
0001589776
-
Differential loss of striatal projection neurons in Huntington disease
-
Reiner A, Albin RL, Anderson KD, D'Amato CJ, Penney JB, Young AB (1988) Differential loss of striatal projection neurons in Huntington disease. Proc Natl Acad Sci 85:5733-5737.
-
(1988)
Proc Natl Acad Sci
, vol.85
, pp. 5733-5737
-
-
Reiner, A.1
Albin, R.L.2
Anderson, K.D.3
D'Amato, C.J.4
Penney, J.B.5
Young, A.B.6
-
38
-
-
74249105655
-
PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum
-
Saavedra A, García-Martínez JM, Xifró X, Giralt A, Torres-Peraza JF, Canals JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E (2010) PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum. Cell Death Differ 17:324-335.
-
(2010)
Cell Death Differ
, vol.17
, pp. 324-335
-
-
Saavedra, A.1
García-Martínez, J.M.2
Xifró, X.3
Giralt, A.4
Torres-Peraza, J.F.5
Canals, J.M.6
Díaz-Hernández, M.7
Lucas, J.J.8
Alberch, J.9
Pérez-Navarro, E.10
-
39
-
-
0036861726
-
Cognitive procedural learning in patients with fronto-striatal lesions
-
Schmidtke K, Manner H, Kaufmann R, Schmolck H (2002) Cognitive procedural learning in patients with fronto-striatal lesions. Learn Mem 9:419-429.
-
(2002)
Learn Mem
, vol.9
, pp. 419-429
-
-
Schmidtke, K.1
Manner, H.2
Kaufmann, R.3
Schmolck, H.4
-
40
-
-
53349101055
-
Compensatory changes in the ubiquitin-proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients
-
Seo H, Kim W, Isacson O (2008) Compensatory changes in the ubiquitin-proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients. Hum Mol Genet 17:3144-3153.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3144-3153
-
-
Seo, H.1
Kim, W.2
Isacson, O.3
-
41
-
-
63849151219
-
Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice
-
Simmons DA, Rex CS, Palmer L, Pandyarajan V, Fedulov V, Gall CM, Lynch G (2009) Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice. Proc Natl Acad Sci 106:4906-4911.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 4906-4911
-
-
Simmons, D.A.1
Rex, C.S.2
Palmer, L.3
Pandyarajan, V.4
Fedulov, V.5
Gall, C.M.6
Lynch, G.7
-
42
-
-
10744227174
-
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
-
Slow EJ, van Raamsdonk J, Rogers D, Coleman SH, Graham RK, Deng Y, Oh R, Bissada N, Hossain SM, Yang YZ, Li XJ, Simpson EM, Gutekunst CA, Leavitt BR, Hayden MR (2003) Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease. Hum Mol Genet 12:1555-1567.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1555-1567
-
-
Slow, E.J.1
Van Raamsdonk, J.2
Rogers, D.3
Coleman, S.H.4
Graham, R.K.5
Deng, Y.6
Oh, R.7
Bissada, N.8
Hossain, S.M.9
Yang, Y.Z.10
Li, X.J.11
Simpson, E.M.12
Gutekunst, C.A.13
Leavitt, B.R.14
Hayden, M.R.15
-
43
-
-
1542286877
-
Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism
-
Spires TL, Grote HE, Varshney NK, Cordery PM, van Dellen A, Blakemore C, Hannan AJ (2004a) Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism. J Neurosci 24:2270-2276.
-
(2004)
J Neurosci
, vol.24
, pp. 2270-2276
-
-
Spires, T.L.1
Grote, H.E.2
Varshney, N.K.3
Cordery, P.M.4
Van Dellen, A.5
Blakemore, C.6
Hannan, A.J.7
-
44
-
-
2942620844
-
Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice
-
Spires TL, Grote HE, Garry S, Cordery PM, Van Dellen A, Blakemore C, Hannan AJ (2004b) Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice. Eur J Neurosci 19:2799-2807.
-
(2004)
Eur J Neurosci
, vol.19
, pp. 2799-2807
-
-
Spires, T.L.1
Grote, H.E.2
Garry, S.3
Cordery, P.M.4
Van Dellen, A.5
Blakemore, C.6
Hannan, A.J.7
-
45
-
-
35548937443
-
Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration
-
Strand AD, Baquet ZC, Aragaki AK, Holmans P, Yang L, Cleren C, Beal MF, Jones L, Kooperberg C, Olson JM, Jones KR (2007) Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration. J Neurosci 27:11758-11768.
-
(2007)
J Neurosci
, vol.27
, pp. 11758-11768
-
-
Strand, A.D.1
Baquet, Z.C.2
Aragaki, A.K.3
Holmans, P.4
Yang, L.5
Cleren, C.6
Beal, M.F.7
Jones, L.8
Kooperberg, C.9
Olson, J.M.10
Jones, K.R.11
-
46
-
-
1342323630
-
DARPP-32: An integrator of neurotransmission
-
Svenningsson P, Nishi A, Fisone G, Girault JA, Nairn AC, Greengard P (2004) DARPP-32: an integrator of neurotransmission. Annu Rev Pharmacol Toxicol 44:269-296.
-
(2004)
Annu Rev Pharmacol Toxicol
, vol.44
, pp. 269-296
-
-
Svenningsson, P.1
Nishi, A.2
Fisone, G.3
Girault, J.A.4
Nairn, A.C.5
Greengard, P.6
-
47
-
-
0037180832
-
Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex
-
Trachtenberg JT, Chen BE, Knott GW, Feng G, Sanes JR, Welker E, Svoboda K (2002) Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature 420:788-794.
-
(2002)
Nature
, vol.420
, pp. 788-794
-
-
Trachtenberg, J.T.1
Chen, B.E.2
Knott, G.W.3
Feng, G.4
Sanes, J.R.5
Welker, E.6
Svoboda, K.7
-
48
-
-
17644368893
-
Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease
-
DOI 10.1523/JNEUROSCI.0590-05.2005
-
Van Raamsdonk JM, Pearson J, Slow EJ, Hossain SM, Leavitt BR, Hayden MR (2005) Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease. J Neurosci 25:4169-4180. (Pubitemid 40563393)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.16
, pp. 4169-4180
-
-
Van Raamsdonk, J.M.1
Pearson, J.2
Slow, E.J.3
Hossain, S.M.4
Leavitt, B.R.5
Hayden, M.R.6
-
49
-
-
33846576161
-
Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease
-
Van Raamsdonk JM, Pearson J, Murphy Z, Hayden MR, Leavitt BR (2006) Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease. BMC Neurosci 7:80.
-
(2006)
BMC Neurosci
, vol.7
, pp. 80
-
-
Van Raamsdonk, J.M.1
Pearson, J.2
Murphy, Z.3
Hayden, M.R.4
Leavitt, B.R.5
-
50
-
-
33947286031
-
Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain
-
Van Raamsdonk JM, Metzler M, Slow E, Pearson J, Schwab C, Carroll J, Graham RK, Leavitt BR, Hayden MR (2007) Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain. Neurobiol Dis 26:189-200.
-
(2007)
Neurobiol Dis
, vol.26
, pp. 189-200
-
-
Van Raamsdonk, J.M.1
Metzler, M.2
Slow, E.3
Pearson, J.4
Schwab, C.5
Carroll, J.6
Graham, R.K.7
Leavitt, B.R.8
Hayden, M.R.9
-
51
-
-
0028800803
-
The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro
-
Ventimiglia R, Mather PE, Jones BE, Lindsay RM (1995) The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro. Eur J Neurosci 7:213-222.
-
(1995)
Eur J Neurosci
, vol.7
, pp. 213-222
-
-
Ventimiglia, R.1
Mather, P.E.2
Jones, B.E.3
Lindsay, R.M.4
-
53
-
-
77951246877
-
Tetrabenazine is neuroprotective in Huntington's disease mice
-
Wang H, Chen X, Li Y, Tang TS, Bezprozvanny I (2010) Tetrabenazine is neuroprotective in Huntington's disease mice. Mol Neurodegener 5:18.
-
(2010)
Mol Neurodegener
, vol.5
, pp. 18
-
-
Wang, H.1
Chen, X.2
Li, Y.3
Tang, T.S.4
Bezprozvanny, I.5
-
54
-
-
0033710349
-
Cortical degeneration in the absence of neurotrophin signaling: Dendritic retraction and neuronal loss after removal of the receptor TrkB
-
Xu B, Zang K, Ruff NL, Zhang YA, McConnell SK, Stryker MP, Reichardt LF (2000) Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB. Neuron 26:233-245.
-
(2000)
Neuron
, vol.26
, pp. 233-245
-
-
Xu, B.1
Zang, K.2
Ruff, N.L.3
Zhang, Y.A.4
McConnell, S.K.5
Stryker, M.P.6
Reichardt, L.F.7
-
55
-
-
0038392755
-
Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
-
Xu B, Goulding EH, Zang K, Cepoi D, Cone RD, Jones KR, Tecott LH, Reichardt LF (2003) Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci 6:736-742.
-
(2003)
Nat Neurosci
, vol.6
, pp. 736-742
-
-
Xu, B.1
Goulding, E.H.2
Zang, K.3
Cepoi, D.4
Cone, R.D.5
Jones, K.R.6
Tecott, L.H.7
Reichardt, L.F.8
-
56
-
-
58849092865
-
Neuronal release of pro-BDNF
-
Yang J, Siao CJ, Nagappan G, Marinic T, Jing D, McGrath K, Chen ZY, Mark W, Tessarollo L, Lee FS, Lu B, Hempstead BL (2009) Neuronal release of pro-BDNF. Nat Neurosci 12:113-115.
-
(2009)
Nat Neurosci
, vol.12
, pp. 113-115
-
-
Yang, J.1
Siao, C.J.2
Nagappan, G.3
Marinic, T.4
Jing, D.5
McGrath, K.6
Chen, Z.Y.7
Mark, W.8
Tessarollo, L.9
Lee, F.S.10
Lu, B.11
Hempstead, B.L.12
-
57
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, MacDonald ME, Friedlander RM, Silani V, Hayden MR, Timmusk T, Sipione S, Cattaneo E (2001) Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 293:493-498.
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
-
58
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Zuccato C, Tartari M, Crotti A, Goffredo D, Valenza M, Conti L, Cataudella T, Leavitt BR, Hayden MR, Timmusk T, Rigamonti D, Cattaneo E (2003) Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat Genet 35:76-83.
-
(2003)
Nat Genet
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
Goffredo, D.4
Valenza, M.5
Conti, L.6
Cataudella, T.7
Leavitt, B.R.8
Hayden, M.R.9
Timmusk, T.10
Rigamonti, D.11
Cattaneo, E.12
|