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Volumn 16, Issue 38, 2010, Pages 4773-4783

Hepatic steatosis, low-grade chronic inflammation and hormone/growth factor/adipokine imbalance

Author keywords

Adipokines; Growth factors; Hepatic steatosis; Hormones; Low grade chronic inflammation

Indexed keywords

ADIPOCYTOKINE; CYTOKINE; FATTY ACID; GROWTH FACTOR;

EID: 78049503241     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i38.4773     Document Type: Article
Times cited : (169)

References (119)
  • 1
    • 0030897513 scopus 로고    scopus 로고
    • Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling
    • Faergeman NJ, Knudsen J. Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling. Biochem J 1997; 323 (Pt 1): 1-12
    • (1997) Biochem J , vol.323 , Issue.1 , pp. 1-12
    • Faergeman, N.J.1    Knudsen, J.2
  • 2
    • 0036798621 scopus 로고    scopus 로고
    • Normal and oxidized low density lipoproteins accumulate deep in physiologically thickened intima of human coronary arteries
    • Fukuchi M, Watanabe J, Kumagai K, Baba S, Shinozaki T, Miura M, Kagaya Y, Shirato K. Normal and oxidized low density lipoproteins accumulate deep in physiologically thickened intima of human coronary arteries. Lab Invest 2002; 82: 1437-1447
    • (2002) Lab Invest , vol.82 , pp. 1437-1447
    • Fukuchi, M.1    Watanabe, J.2    Kumagai, K.3    Baba, S.4    Shinozaki, T.5    Miura, M.6    Kagaya, Y.7    Shirato, K.8
  • 4
    • 0031014830 scopus 로고    scopus 로고
    • Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
    • Boden G. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 1997; 46: 3-10
    • (1997) Diabetes , vol.46 , pp. 3-10
    • Boden, G.1
  • 5
    • 0032829745 scopus 로고    scopus 로고
    • Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects
    • Santomauro AT, Boden G, Silva ME, Rocha DM, Santos RF, Ursich MJ, Strassmann PG, Wajchenberg BL. Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects. Diabetes 1999; 48: 1836-1841
    • (1999) Diabetes , vol.48 , pp. 1836-1841
    • Santomauro, A.T.1    Boden, G.2    Silva, M.E.3    Rocha, D.M.4    Santos, R.F.5    Ursich, M.J.6    Strassmann, P.G.7    Wajchenberg, B.L.8
  • 7
    • 0029151863 scopus 로고
    • Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications
    • Unger RH. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications. Diabetes 1995; 44: 863-870
    • (1995) Diabetes , vol.44 , pp. 863-870
    • Unger, R.H.1
  • 8
    • 0034975220 scopus 로고    scopus 로고
    • The role of lipids in the pathogenesis of muscle insulin resistance and beta cell failure in type II diabetes and obesity
    • Kraegen EW, Cooney GJ, Ye JM, Thompson AL, Furler SM. The role of lipids in the pathogenesis of muscle insulin resistance and beta cell failure in type II diabetes and obesity. Exp Clin Endocrinol Diabetes 2001; 109 Suppl 2: S189-S201
    • (2001) Exp Clin Endocrinol Diabetes , vol.109 , Issue.2
    • Kraegen, E.W.1    Cooney, G.J.2    Ye, J.M.3    Thompson, A.L.4    Furler, S.M.5
  • 10
    • 0033860359 scopus 로고    scopus 로고
    • Insulin resistance and cardiovascular disease
    • Ginsberg HN. Insulin resistance and cardiovascular disease. J Clin Invest 2000; 106: 453-458
    • (2000) J Clin Invest , vol.106 , pp. 453-458
    • Ginsberg, H.N.1
  • 11
    • 0025748673 scopus 로고
    • Metabolic implications of body fat distribution
    • Björntorp P. Metabolic implications of body fat distribution. Diabetes Care 1991; 14: 1132-1143
    • (1991) Diabetes Care , vol.14 , pp. 1132-1143
    • Björntorp, P.1
  • 12
    • 0028825129 scopus 로고
    • Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin
    • Rebrin K, Steil GM, Getty L, Bergman RN. Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes 1995; 44: 1038-1045
    • (1995) Diabetes , vol.44 , pp. 1038-1045
    • Rebrin, K.1    Steil, G.M.2    Getty, L.3    Bergman, R.N.4
  • 13
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963; 1: 785-789
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 14
    • 0036230414 scopus 로고    scopus 로고
    • Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: The insulin resistance atherosclerosis study
    • Festa A, D'Agostino R Jr, Tracy RP, Haffner SM. Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes 2002; 51: 1131-1137
    • (2002) Diabetes , vol.51 , pp. 1131-1137
    • Festa, A.1    D'agostino Jr., R.2    Tracy, R.P.3    Haffner, S.M.4
  • 15
    • 63849230733 scopus 로고    scopus 로고
    • Young adult obese subjects with and without insulin resistance: What is the role of chronic inflammation and how to weigh it non-invasively?
    • Tarantino G, Colicchio P, Conca P, Finelli C, Di Minno MN, Tarantino M, Capone D, Pasanisi F. Young adult obese subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively? J Inflamm (Lond) 2009; 6: 6
    • (2009) J Inflamm (Lond) , vol.6 , pp. 6
    • Tarantino, G.1    Colicchio, P.2    Conca, P.3    Finelli, C.4    Di Minno, M.N.5    Tarantino, M.6    Capone, D.7    Pasanisi, F.8
  • 19
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 2005; 11: 183-190
    • (2005) Nat Med , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5    Lee, J.6    Shoelson, S.E.7
  • 20
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
    • Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol 2000; 18: 621-663
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 21
    • 0242268894 scopus 로고    scopus 로고
    • Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice
    • Klover PJ, Zimmers TA, Koniaris LG, Mooney RA. Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes 2003; 52: 2784-2789
    • (2003) Diabetes , vol.52 , pp. 2784-2789
    • Klover, P.J.1    Zimmers, T.A.2    Koniaris, L.G.3    Mooney, R.A.4
  • 23
    • 0034076660 scopus 로고    scopus 로고
    • Fuel selection in human skeletal muscle in insulin resistance: A reexamination
    • Kelley DE, Mandarino LJ. Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes 2000; 49: 677-683
    • (2000) Diabetes , vol.49 , pp. 677-683
    • Kelley, D.E.1    Mandarino, L.J.2
  • 24
    • 0030765908 scopus 로고    scopus 로고
    • Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat
    • Goodpaster BH, Thaete FL, Simoneau JA, Kelley DE. Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 1997; 46: 1579-1585
    • (1997) Diabetes , vol.46 , pp. 1579-1585
    • Goodpaster, B.H.1    Thaete, F.L.2    Simoneau, J.A.3    Kelley, D.E.4
  • 25
    • 0035048503 scopus 로고    scopus 로고
    • Contributions of total body fat, abdominal subcutaneous adipose tissue compartments, and visceral adipose tissue to the metabolic complications of obesity
    • Smith SR, Lovejoy JC, Greenway F, Ryan D, deJonge L, de la Bretonne J, Volafova J, Bray GA. Contributions of total body fat, abdominal subcutaneous adipose tissue compartments, and visceral adipose tissue to the metabolic complications of obesity. Metabolism 2001; 50: 425-435
    • (2001) Metabolism , vol.50 , pp. 425-435
    • Smith, S.R.1    Lovejoy, J.C.2    Greenway, F.3    Ryan, D.4    Dejonge, L.5    de la, B.J.6    Volafova, J.7    Bray, G.A.8
  • 26
    • 0033044289 scopus 로고    scopus 로고
    • Insulin sensitivity and serum triglyceride level in obese white and black women: Relationship to visceral and truncal subcutaneous fat
    • Marcus MA, Murphy L, Pi-Sunyer FX, Albu JB. Insulin sensitivity and serum triglyceride level in obese white and black women: relationship to visceral and truncal subcutaneous fat. Metabolism 1999; 48: 194-199
    • (1999) Metabolism , vol.48 , pp. 194-199
    • Marcus, M.A.1    Murphy, L.2    Pi-Sunyer, F.X.3    Albu, J.B.4
  • 28
    • 0033595121 scopus 로고    scopus 로고
    • Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus
    • Shepherd PR, Kahn BB. Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus. N Engl J Med 1999; 341: 248-257
    • (1999) N Engl J Med , vol.341 , pp. 248-257
    • Shepherd, P.R.1    Kahn, B.B.2
  • 29
    • 0030931962 scopus 로고    scopus 로고
    • Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase
    • Weinstock PH, Levak-Frank S, Hudgins LC, Radner H, Friedman JM, Zechner R, Breslow JL. Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase. Proc Natl Acad Sci USA 1997; 94: 10261-10266
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10261-10266
    • Weinstock, P.H.1    Levak-Frank, S.2    Hudgins, L.C.3    Radner, H.4    Friedman, J.M.5    Zechner, R.6    Breslow, J.L.7
  • 31
    • 0033580938 scopus 로고    scopus 로고
    • Novel form of lipolysis inducedby leptin
    • Wang MY, Lee Y, Unger RH. Novel form of lipolysis inducedby leptin. J Biol Chem 1999; 274: 17541-17544
    • (1999) J Biol Chem , vol.274 , pp. 17541-17544
    • Wang, M.Y.1    Lee, Y.2    Unger, R.H.3
  • 32
    • 0030007427 scopus 로고    scopus 로고
    • ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism
    • Kim JB, Spiegelman BM. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev 1996; 10: 1096-1107
    • (1996) Genes Dev , vol.10 , pp. 1096-1107
    • Kim, J.B.1    Spiegelman, B.M.2
  • 33
    • 0033849777 scopus 로고    scopus 로고
    • Obesity and insulin resistance
    • Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Invest 2000; 106: 473-481
    • (2000) J Clin Invest , vol.106 , pp. 473-481
    • Kahn, B.B.1    Flier, J.S.2
  • 36
    • 0031041075 scopus 로고    scopus 로고
    • Regulating adipogenesis
    • Mandrup S, Lane MD. Regulating adipogenesis. J Biol Chem 1997; 272: 5367-5370
    • (1997) J Biol Chem , vol.272 , pp. 5367-5370
    • Mandrup, S.1    Lane, M.D.2
  • 37
    • 0032516081 scopus 로고    scopus 로고
    • ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand
    • Kim JB, Wright HM, Wright M, Spiegelman BM. ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand. Proc Natl Acad Sci USA 1998; 95: 4333-4337
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4333-4337
    • Kim, J.B.1    Wright, H.M.2    Wright, M.3    Spiegelman, B.M.4
  • 38
    • 0032429617 scopus 로고    scopus 로고
    • Association of fat cell size and paracrine growth factors in development of hyperplastic obesity
    • Marques BG, Hausman DB, Martin RJ. Association of fat cell size and paracrine growth factors in development of hyperplastic obesity. Am J Physiol 1998; 275: R1898-R1908
    • (1998) Am J Physiol , vol.275
    • Marques, B.G.1    Hausman, D.B.2    Martin, R.J.3
  • 39
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesitylinked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesitylinked insulin resistance. Science 1993; 259: 87-91
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 42
    • 0030748260 scopus 로고    scopus 로고
    • Signal transduction mechanisms in nutrient-induced insulin secretion
    • Prentki M, Tornheim K, Corkey BE. Signal transduction mechanisms in nutrient-induced insulin secretion. Diabetologia 1997; 40 Suppl 2: S32-S41
    • (1997) Diabetologia , vol.40 , Issue.2
    • Prentki, M.1    Tornheim, K.2    Corkey, B.E.3
  • 43
    • 0032478314 scopus 로고    scopus 로고
    • Fatty acidinduced beta cell apoptosis: A link between obesity and diabetes
    • Shimabukuro M, Zhou YT, Levi M, Unger RH. Fatty acidinduced beta cell apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci USA 1998; 95: 2498-2502
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2498-2502
    • Shimabukuro, M.1    Zhou, Y.T.2    Levi, M.3    Unger, R.H.4
  • 44
    • 0034613316 scopus 로고    scopus 로고
    • Fatty acid regulation of gene transcription
    • Duplus E, Glorian M, Forest C. Fatty acid regulation of gene transcription. J Biol Chem 2000; 275: 30749-30752
    • (2000) J Biol Chem , vol.275 , pp. 30749-30752
    • Duplus, E.1    Glorian, M.2    Forest, C.3
  • 45
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown MS, Goldstein JL. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 1997; 89: 331-340
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 48
    • 74649087136 scopus 로고
    • The influence of purified growth hormone on fasting metabolism
    • Szego CM, White A. The influence of purified growth hormone on fasting metabolism. J Clin Endocrinol Metab 1948; 8: 594
    • (1948) J Clin Endocrinol Metab , vol.8 , pp. 594
    • Szego, C.M.1    White, A.2
  • 49
    • 65549119187 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor signal transduction and the Janus Kinase/Signal Transducer and Activator of Transcription (JAK-STAT) pathway
    • Himpe E, Kooijman R. Insulin-like growth factor-I receptor signal transduction and the Janus Kinase/Signal Transducer and Activator of Transcription (JAK-STAT) pathway. Biofactors 2009; 35: 76-81
    • (2009) Biofactors , vol.35 , pp. 76-81
    • Himpe, E.1    Kooijman, R.2
  • 50
    • 0032239547 scopus 로고    scopus 로고
    • Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human
    • Giustina A, Veldhuis JD. Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human. Endocr Rev 1998; 19: 717-797
    • (1998) Endocr Rev , vol.19 , pp. 717-797
    • Giustina, A.1    Veldhuis, J.D.2
  • 51
    • 4444284454 scopus 로고    scopus 로고
    • Free insulin-like growth factors -- measurements and relationships to growth hormone secretion and glucose homeostasis
    • Frystyk J. Free insulin-like growth factors -- measurements and relationships to growth hormone secretion and glucose homeostasis. Growth Horm IGF Res 2004; 14: 337-375
    • (2004) Growth Horm IGF Res , vol.14 , pp. 337-375
    • Frystyk, J.1
  • 52
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001; 414: 799-806
    • (2001) Nature , vol.414 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 53
    • 33745218966 scopus 로고    scopus 로고
    • Beginning to end: Cardiovascular implications of growth hormone (GH) deficiency and GH therapy
    • Colao A, Di Somma C, Savanelli MC, De Leo M, Lombardi G. Beginning to end: cardiovascular implications of growth hormone (GH) deficiency and GH therapy. Growth Horm IGF Res 2006; 16 Suppl A: S41-S48
    • (2006) Growth Horm IGF Res , vol.16 , Issue.A
    • Colao, A.1    Di Somma, C.2    Savanelli, M.C.3    de Leo, M.4    Lombardi, G.5
  • 54
    • 0033308713 scopus 로고    scopus 로고
    • The growth hormone (GH) response to the arginine plus GHreleasing hormone test is correlated to the severity of lipid profile abnormalities in adult patients with GH deficiency
    • Colao A, Cerbone G, Pivonello R, Aimaretti G, Loche S, Di Somma C, Faggiano A, Corneli G, Ghigo E, Lombardi G. The growth hormone (GH) response to the arginine plus GHreleasing hormone test is correlated to the severity of lipid profile abnormalities in adult patients with GH deficiency. J Clin Endocrinol Metab 1999; 84: 1277-1282
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1277-1282
    • Colao, A.1    Cerbone, G.2    Pivonello, R.3    Aimaretti, G.4    Loche, S.5    Di Somma, C.6    Faggiano, A.7    Corneli, G.8    Ghigo, E.9    Lombardi, G.10
  • 56
    • 36849033443 scopus 로고    scopus 로고
    • The somatomedin hypothesis 2007: 50 years later
    • Kaplan SA, Cohen P. The somatomedin hypothesis 2007: 50 years later. J Clin Endocrinol Metab 2007; 92: 4529-4535
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 4529-4535
    • Kaplan, S.A.1    Cohen, P.2
  • 57
    • 0032858944 scopus 로고    scopus 로고
    • Impaired adipogenesis in insulin-like growth factor binding protein-1 transgenic mice
    • Rajkumar K, Modric T, Murphy LJ. Impaired adipogenesis in insulin-like growth factor binding protein-1 transgenic mice. J Endocrinol 1999; 162: 457-465
    • (1999) J Endocrinol , vol.162 , pp. 457-465
    • Rajkumar, K.1    Modric, T.2    Murphy, L.J.3
  • 58
    • 32144461714 scopus 로고    scopus 로고
    • Longterm IGF-I treatment of children with Laron syndrome increases adiposity
    • Laron Z, Ginsberg S, Lilos P, Arbiv M, Vaisman N. Longterm IGF-I treatment of children with Laron syndrome increases adiposity. Growth Horm IGF Res 2006; 16: 61-64
    • (2006) Growth Horm IGF Res , vol.16 , pp. 61-64
    • Laron, Z.1    Ginsberg, S.2    Lilos, P.3    Arbiv, M.4    Vaisman, N.5
  • 59
    • 13544273450 scopus 로고    scopus 로고
    • Are the metabolic effects of GH and IGF-I separable?
    • Mauras N, Haymond MW. Are the metabolic effects of GH and IGF-I separable? Growth Horm IGF Res 2005; 15: 19-27
    • (2005) Growth Horm IGF Res , vol.15 , pp. 19-27
    • Mauras, N.1    Haymond, M.W.2
  • 60
    • 33846436784 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 induces insulin resistance in adipocytes in vitro and in rats in vivo
    • Kim HS, Ali O, Shim M, Lee KW, Vuguin P, Muzumdar R, Barzilai N, Cohen P. Insulin-like growth factor binding protein-3 induces insulin resistance in adipocytes in vitro and in rats in vivo. Pediatr Res 2007; 61: 159-164
    • (2007) Pediatr Res , vol.61 , pp. 159-164
    • Kim, H.S.1    Ali, O.2    Shim, M.3    Lee, K.W.4    Vuguin, P.5    Muzumdar, R.6    Barzilai, N.7    Cohen, P.8
  • 61
    • 0032858944 scopus 로고    scopus 로고
    • Impaired adipogenesis in insulin-like growth factor binding protein-1 transgenic mice
    • Rajkumar K, Modric T, Murphy LJ. Impaired adipogenesis in insulin-like growth factor binding protein-1 transgenic mice. J Endocrinol 1999; 162: 457-465
    • (1999) J Endocrinol , vol.162 , pp. 457-465
    • Rajkumar, K.1    Modric, T.2    Murphy, L.J.3
  • 63
    • 54049143241 scopus 로고    scopus 로고
    • Relationships between serum IGF1 levels, blood pressure, and glucose tolerance: An observational, exploratory study in 404 subjects
    • Colao A, Di Somma C, Cascella T, Pivonello R, Vitale G, Grasso LF, Lombardi G, Savastano S. Relationships between serum IGF1 levels, blood pressure, and glucose tolerance: an observational, exploratory study in 404 subjects. Eur J Endocrinol 2008; 159: 389-397
    • (2008) Eur J Endocrinol , vol.159 , pp. 389-397
    • Colao, A.1    Di Somma, C.2    Cascella, T.3    Pivonello, R.4    Vitale, G.5    Grasso, L.F.6    Lombardi, G.7    Savastano, S.8
  • 64
    • 0842291511 scopus 로고    scopus 로고
    • The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: The Rancho Bernardo Study
    • Laughlin GA, Barrett-Connor E, Criqui MH, Kritz-Silverstein D. The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: the Rancho Bernardo Study. J Clin Endocrinol Metab 2004; 89: 114-120
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 114-120
    • Laughlin, G.A.1    Barrett-Connor, E.2    Criqui, M.H.3    Kritz-Silverstein, D.4
  • 70
    • 8844263764 scopus 로고    scopus 로고
    • IGF-binding proteins mediate TGFbeta 1-induced apoptosis in bovine mammary epithelial BMETUV1 cells
    • Gajewska M, Motyl T. IGF-binding proteins mediate TGFbeta 1-induced apoptosis in bovine mammary epithelial BMETUV1 cells. Comp Biochem Physiol C Toxicol Pharmacol 2004; 139: 65-75
    • (2004) Comp Biochem Physiol C Toxicol Pharmacol , vol.139 , pp. 65-75
    • Gajewska, M.1    Motyl, T.2
  • 71
    • 0033974348 scopus 로고    scopus 로고
    • The adipoinsular axis: Effects of leptin on pancreatic beta-cells
    • Kieffer TJ, Habener JF. The adipoinsular axis: effects of leptin on pancreatic beta-cells. Am J Physiol Endocrinol Metab 2000; 278: E1-E14
    • (2000) Am J Physiol Endocrinol Metab , vol.278
    • Kieffer, T.J.1    Habener, J.F.2
  • 73
    • 0035909997 scopus 로고    scopus 로고
    • Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS)
    • Wallace AM, McMahon AD, Packard CJ, Kelly A, Shepherd J, Gaw A, Sattar N. Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS). Circulation 2001; 104: 3052-3056
    • (2001) Circulation , vol.104 , pp. 3052-3056
    • Wallace, A.M.1    McMahon, A.D.2    Packard, C.J.3    Kelly, A.4    Shepherd, J.5    Gaw, A.6    Sattar, N.7
  • 76
    • 0032796327 scopus 로고    scopus 로고
    • Etiology of the metabolic syndrome: Potential role of insulin resistance, leptin resistance, and other players
    • Zimmet P, Boyko EJ, Collier GR, de Courten M. Etiology of the metabolic syndrome: potential role of insulin resistance, leptin resistance, and other players. Ann N Y Acad Sci 1999; 892: 25-44
    • (1999) Ann N Y Acad Sci , vol.892 , pp. 25-44
    • Zimmet, P.1    Boyko, E.J.2    Collier, G.R.3    de Courten, M.4
  • 78
    • 0033756298 scopus 로고    scopus 로고
    • Leptin resistance is associated with hypothalamic leptin receptor mRNA and protein downregulation
    • Martin RL, Perez E, He YJ, Dawson R Jr, Millard WJ. Leptin resistance is associated with hypothalamic leptin receptor mRNA and protein downregulation. Metabolism 2000; 49: 1479-1484
    • (2000) Metabolism , vol.49 , pp. 1479-1484
    • Martin, R.L.1    Perez, E.2    He, Y.J.3    Dawson Jr., R.4    Millard, W.J.5
  • 83
    • 3042534522 scopus 로고    scopus 로고
    • Soluble leptin receptor and soluble receptor-bound fraction of leptin in the metabolic syndrome
    • Sandhofer A, Laimer M, Ebenbichler CF, Kaser S, Paulweber B, Patsch JR. Soluble leptin receptor and soluble receptor-bound fraction of leptin in the metabolic syndrome. Obes Res 2003; 11: 760-768
    • (2003) Obes Res , vol.11 , pp. 760-768
    • Sandhofer, A.1    Laimer, M.2    Ebenbichler, C.F.3    Kaser, S.4    Paulweber, B.5    Patsch, J.R.6
  • 86
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
    • Hotta K, Funahashi T, Bodkin NL, Ortmeyer HK, Arita Y, Hansen BC, Matsuzawa Y. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 2001; 50: 1126-1133
    • (2001) Diabetes , vol.50 , pp. 1126-1133
    • Hotta, K.1    Funahashi, T.2    Bodkin, N.L.3    Ortmeyer, H.K.4    Arita, Y.5    Hansen, B.C.6    Matsuzawa, Y.7
  • 89
    • 14144249423 scopus 로고    scopus 로고
    • Is adiponectin involved in the pathogenesis of nonalcoholic steatohepatitis? A preliminary human study
    • Vuppalanchi R, Marri S, Kolwankar D, Considine RV, Chalasani N. Is adiponectin involved in the pathogenesis of nonalcoholic steatohepatitis? A preliminary human study. J Clin Gastroenterol 2005; 39: 237-242
    • (2005) J Clin Gastroenterol , vol.39 , pp. 237-242
    • Vuppalanchi, R.1    Marri, S.2    Kolwankar, D.3    Considine, R.V.4    Chalasani, N.5
  • 93
    • 17444421501 scopus 로고    scopus 로고
    • IGF-I downregulates resistin gene expression and protein secretion
    • Chen YH, Hung PF, Kao YH. IGF-I downregulates resistin gene expression and protein secretion. Am J Physiol Endocrinol Metab 2005; 288: E1019-E1027
    • (2005) Am J Physiol Endocrinol Metab , vol.288
    • Chen, Y.H.1    Hung, P.F.2    Kao, Y.H.3
  • 94
    • 0036365870 scopus 로고    scopus 로고
    • Resistin gene expression in human adipocytes is not related to insulin resistance
    • Janke J, Engeli S, Gorzelniak K, Luft FC, Sharma AM. Resistin gene expression in human adipocytes is not related to insulin resistance. Obes Res 2002; 10: 1-5
    • (2002) Obes Res , vol.10 , pp. 1-5
    • Janke, J.1    Engeli, S.2    Gorzelniak, K.3    Luft, F.C.4    Sharma, A.M.5
  • 96
    • 14344265507 scopus 로고    scopus 로고
    • Stimulated resistin expression in white adipose of rats with bile duct ligation-induced liver cirrhosis: Relationship to cirrhotic hyperinsulinemia and increased tumor necrosis factor-alpha
    • Lin SY, Sheu WH, Chen WY, Lee FY, Huang CJ. Stimulated resistin expression in white adipose of rats with bile duct ligation-induced liver cirrhosis: relationship to cirrhotic hyperinsulinemia and increased tumor necrosis factor-alpha. Mol Cell Endocrinol 2005; 232: 1-8
    • (2005) Mol Cell Endocrinol , vol.232 , pp. 1-8
    • Lin, S.Y.1    Sheu, W.H.2    Chen, W.Y.3    Lee, F.Y.4    Huang, C.J.5
  • 97
    • 0020533259 scopus 로고
    • Obesity as an independent risk factor for cardiovascular disease: A 26-year follow-up of participants in the Framingham Heart Study
    • Hubert HB, Feinleib M, McNamara PM, Castelli WP. Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 1983; 67: 968-977
    • (1983) Circulation , vol.67 , pp. 968-977
    • Hubert, H.B.1    Feinleib, M.2    McNamara, P.M.3    Castelli, W.P.4
  • 98
    • 0033818023 scopus 로고    scopus 로고
    • The metabolic syndrome, LDL particle size, and atherosclerosis: The Atherosclerosis and Insulin Resistance (AIR) study
    • Hulthe J, Bokemark L, Wikstrand J, Fagerberg B. The metabolic syndrome, LDL particle size, and atherosclerosis: the Atherosclerosis and Insulin Resistance (AIR) study. Arterioscler Thromb Vasc Biol 2000; 20: 2140-2147
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2140-2147
    • Hulthe, J.1    Bokemark, L.2    Wikstrand, J.3    Fagerberg, B.4
  • 101
    • 0034704893 scopus 로고    scopus 로고
    • C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000; 342: 836-843
    • (2000) N Engl J Med , vol.342 , pp. 836-843
    • Ridker, P.M.1    Hennekens, C.H.2    Buring, J.E.3    Rifai, N.4
  • 102
    • 0025190892 scopus 로고
    • Interleukin-6 and the acute phase response
    • Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response. Biochem J 1990; 265: 621-636
    • (1990) Biochem J , vol.265 , pp. 621-636
    • Heinrich, P.C.1    Castell, J.V.2    Andus, T.3
  • 107
    • 0031079738 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is the major angiogenic factor in omentum: Mechanism of the omentummediated angiogenesis
    • Zhang QX, Magovern CJ, Mack CA, Budenbender KT, Ko W, Rosengart TK. Vascular endothelial growth factor is the major angiogenic factor in omentum: mechanism of the omentummediated angiogenesis. J Surg Res 1997; 67: 147-154
    • (1997) J Surg Res , vol.67 , pp. 147-154
    • Zhang, Q.X.1    Magovern, C.J.2    Mack, C.A.3    Budenbender, K.T.4    Ko, W.5    Rosengart, T.K.6
  • 108
    • 1642450652 scopus 로고    scopus 로고
    • Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice
    • Redaelli CA, Semela D, Carrick FE, Ledermann M, Candinas D, Sauter B, Dufour JF. Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice. J Hepatol 2004; 40: 305-312
    • (2004) J Hepatol , vol.40 , pp. 305-312
    • Redaelli, C.A.1    Semela, D.2    Carrick, F.E.3    Ledermann, M.4    Candinas, D.5    Sauter, B.6    Dufour, J.F.7
  • 110
    • 39449083509 scopus 로고    scopus 로고
    • Basal metabolic rate in morbidly obese patients with non-alcoholic fatty liver disease
    • Tarantino G, Marra M, Contaldo F, Pasanisi F. Basal metabolic rate in morbidly obese patients with non-alcoholic fatty liver disease. Clin Invest Med 2008; 31: E24-E29
    • (2008) Clin Invest Med , vol.31
    • Tarantino, G.1    Marra, M.2    Contaldo, F.3    Pasanisi, F.4
  • 111
    • 34250344637 scopus 로고    scopus 로고
    • A prospective study of acute drug-induced liver injury in patients suffering from non-alcoholic fatty liver disease
    • Tarantino G, Conca P, Basile V, Gentile A, Capone D, Polichetti G, Leo E. A prospective study of acute drug-induced liver injury in patients suffering from non-alcoholic fatty liver disease. Hepatol Res 2007; 37: 410-415
    • (2007) Hepatol Res , vol.37 , pp. 410-415
    • Tarantino, G.1    Conca, P.2    Basile, V.3    Gentile, A.4    Capone, D.5    Polichetti, G.6    Leo, E.7
  • 114
    • 39549113664 scopus 로고    scopus 로고
    • Effect of peroxisome proliferatoractivated receptors-gamma and co-activator-1alpha genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people
    • Hui Y, Yu-Yuan L, Yu-Qiang N, Wei-Hong S, Yan-Lei D, Xiao-Bo L, Yong-Jian Z. Effect of peroxisome proliferatoractivated receptors-gamma and co-activator-1alpha genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people. Liver Int 2008; 28: 385-392
    • (2008) Liver Int , vol.28 , pp. 385-392
    • Hui, Y.1    Yu-Yuan, L.2    Yu-Qiang, N.3    Wei-Hong, S.4    Yan-Lei, D.5    Xiao-Bo, L.6    Yong-Jian, Z.7
  • 115
    • 67649210759 scopus 로고    scopus 로고
    • Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis
    • Zhang S, Wang J, Liu Q, Harnish DC. Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis. J Hepatol 2009; 51: 380-388
    • (2009) J Hepatol , vol.51 , pp. 380-388
    • Zhang, S.1    Wang, J.2    Liu, Q.3    Harnish, D.C.4
  • 116
    • 68949091995 scopus 로고    scopus 로고
    • Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alphadependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones
    • Hwahng SH, Ki SH, Bae EJ, Kim HE, Kim SG. Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alphadependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones. Hepatology 2009; 49: 1913-1925
    • (2009) Hepatology , vol.49 , pp. 1913-1925
    • Hwahng, S.H.1    Ki, S.H.2    Bae, E.J.3    Kim, H.E.4    Kim, S.G.5
  • 118
    • 33846900939 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease: Further expression of the metabolic syndrome
    • Tarantino G, Saldalamacchia G, Conca P, Arena A. Non-alcoholic fatty liver disease: further expression of the metabolic syndrome. J Gastroenterol Hepatol 2007; 22: 293-303
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 293-303
    • Tarantino, G.1    Saldalamacchia, G.2    Conca, P.3    Arena, A.4
  • 119
    • 34648816548 scopus 로고    scopus 로고
    • Should nonalcoholic fatty liver disease be regarded as a hepatic illness only?
    • Tarantino G. Should nonalcoholic fatty liver disease be regarded as a hepatic illness only? World J Gastroenterol 2007; 13: 4669-4672
    • (2007) World J Gastroenterol , vol.13 , pp. 4669-4672
    • Tarantino, G.1


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