메뉴 건너뛰기




Volumn 892, Issue , 1999, Pages 25-44

Etiology of the metabolic syndrome: Potential role of insulin resistance, leptin resistance, and other players

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; INSULIN; LEPTIN;

EID: 0032796327     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07783.x     Document Type: Conference Paper
Times cited : (210)

References (78)
  • 1
    • 0024758290 scopus 로고
    • Non-insulin-dependent (Type 2) diabetes mellitus - Does it really exist?
    • 1. Zimmet, P. 1989. Non-insulin-dependent (Type 2) diabetes mellitus - Does it really exist? Diabetic Med. 6: 728-735.
    • (1989) Diabetic Med. , vol.6 , pp. 728-735
    • Zimmet, P.1
  • 2
    • 0029067892 scopus 로고
    • The pathogenesis and prevention of diabetes in adults
    • 2. Zimmet, P. Z. 1995. The pathogenesis and prevention of diabetes in adults. Diabetes Care 18: 1050-1064.
    • (1995) Diabetes Care , vol.18 , pp. 1050-1064
    • Zimmet, P.Z.1
  • 3
    • 0030795740 scopus 로고    scopus 로고
    • The changing face of macrovascular disease in non-insulin dependent diabetes mellitus in different cultures: An epidemic in progress
    • 3. Zimmet, P. & K. G. M. M. Alberti. 1997. The changing face of macrovascular disease in non-insulin dependent diabetes mellitus in different cultures: an epidemic in progress. Lancet 350(Suppl. 1): S1-S4.
    • (1997) Lancet , vol.350 , Issue.SUPPL. 1
    • Zimmet, P.1    Alberti, K.G.M.M.2
  • 4
    • 0024391834 scopus 로고
    • The deadly quartet: Upper-body obesity, glucose intolerance, hypertriglyceridaemia, and hypertension
    • 4. Kaplan, N. M. 1989. The deadly quartet: Upper-body obesity, glucose intolerance, hypertriglyceridaemia, and hypertension. Arch. Int. Med. 149: 1514-1520.
    • (1989) Arch. Int. Med. , vol.149 , pp. 1514-1520
    • Kaplan, N.M.1
  • 5
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • 5. Reaven, G. M. 1988. Role of insulin resistance in human disease. Diabetes 37: 1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 6
    • 0026021161 scopus 로고
    • Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease
    • 6. De Fronzo, R. & E. Ferrannini. 1991. Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease. Diabetes Care 14: 173-194.
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • De Fronzo, R.1    Ferrannini, E.2
  • 7
    • 0026537577 scopus 로고
    • Challenges in diabetes epidemiology - From west to the rest
    • 7. Zimmet, P. 1992. Challenges in diabetes epidemiology - from West to the rest. Diabetes Care 15: 232-252.
    • (1992) Diabetes Care , vol.15 , pp. 232-252
    • Zimmet, P.1
  • 8
    • 0025367559 scopus 로고
    • Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?
    • 8. Haffner, S. M., M. P. Stern, H. P. Hazuda, et al. 1990. Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes? JAMA 263: 2893-2898.
    • (1990) JAMA , vol.263 , pp. 2893-2898
    • Haffner, S.M.1    Stern, M.P.2    Hazuda, H.P.3
  • 9
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1. Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation
    • 9. Alberti, K. G. M. M. & P. Z. Zimmet for the World Health Organization Consultation. 1998. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1. Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabetic Med. 15: 539-553.
    • (1998) Diabetic Med. , vol.15 , pp. 539-553
    • Alberti, K.G.M.M.1    Zimmet, P.Z.2
  • 10
    • 0027180608 scopus 로고
    • How good a marker is insulin level for insulin resistance?
    • 10. Laakso, M. 1993. How good a marker is insulin level for insulin resistance? Am. J. Epidemiol. 137: 959-965.
    • (1993) Am. J. Epidemiol. , vol.137 , pp. 959-965
    • Laakso, M.1
  • 11
    • 0026738794 scopus 로고
    • In defense of insulin: A critique of syndrome X
    • 11. Jarrett, R. J. 1995. In defense of insulin: A critique of syndrome X. Lancet 340: 469-471.
    • (1995) Lancet , vol.340 , pp. 469-471
    • Jarrett, R.J.1
  • 12
    • 0028961110 scopus 로고
    • Diabetes and cardiovascular disease: The "common soil" hypothesis
    • 12. Stern, M. P. 1995. Diabetes and cardiovascular disease: the "common soil" hypothesis. Diabetes 44: 369-374.
    • (1995) Diabetes , vol.44 , pp. 369-374
    • Stern, M.P.1
  • 13
    • 0025649883 scopus 로고
    • An inconsistent relationship between insulin and blood pressure in three Pacific island populations
    • 13. Collins, V. R., G. K. Dowse, C. F. Finch, et al. 1990. An inconsistent relationship between insulin and blood pressure in three Pacific island populations. J. Clin. Epidemiol. 43: 1369-1378.
    • (1990) J. Clin. Epidemiol. , vol.43 , pp. 1369-1378
    • Collins, V.R.1    Dowse, G.K.2    Finch, C.F.3
  • 14
    • 0028276438 scopus 로고
    • Is hyperinsulinaemia a central characteristic of a chronic cardiovascular risk factor syndrome? Mixed findings in Asian Indian, Creole and Chinese Mauritians
    • 14. Zimmet, P. Z., V. R. Collins, G. K. Dowse, et al. 1994. Is hyperinsulinaemia a central characteristic of a chronic cardiovascular risk factor syndrome? Mixed findings in Asian Indian, Creole and Chinese Mauritians. Diabetic Med. 11: 388-396.
    • (1994) Diabetic Med. , vol.11 , pp. 388-396
    • Zimmet, P.Z.1    Collins, V.R.2    Dowse, G.K.3
  • 15
    • 0032966682 scopus 로고    scopus 로고
    • Diabetes epidemiology as a tool to trigger diabetes research and care
    • 15. Zimmet, P. 1999. Diabetes epidemiology as a tool to trigger diabetes research and care. Diabetologia 42: 499-518.
    • (1999) Diabetologia , vol.42 , pp. 499-518
    • Zimmet, P.1
  • 16
    • 0030943158 scopus 로고    scopus 로고
    • Hyperleptinaemia: The missing link in the metabolic syndrome?
    • 16. De Courten, M., P. Zimmet & A. Hodge. 1997. Hyperleptinaemia: the missing link in the Metabolic Syndrome? Diabetic Med. 14: 200-208.
    • (1997) Diabetic Med. , vol.14 , pp. 200-208
    • De Courten, M.1    Zimmet, P.2    Hodge, A.3
  • 17
    • 77049292123 scopus 로고
    • The degree of masculine differentiation of obesity: A factor determining predisposition to diabetes, arteriosclerosis, gout and uric calculus disease
    • 17. Vague, J. 1956. The degree of masculine differentiation of obesity: a factor determining predisposition to diabetes, arteriosclerosis, gout and uric calculus disease. Am. J. Clin. Nutr. 4: 20-34.
    • (1956) Am. J. Clin. Nutr. , vol.4 , pp. 20-34
    • Vague, J.1
  • 18
    • 0023120630 scopus 로고
    • Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp
    • 18. Bergman, R. N., R. Prager, A. Volund, et al. 1987. Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. J. Clin. Invest. 79: 790-800.
    • (1987) J. Clin. Invest. , vol.79 , pp. 790-800
    • Bergman, R.N.1    Prager, R.2    Volund, A.3
  • 19
    • 0018520840 scopus 로고
    • Glucose clamp technique: A method for quantifying insulin secretion and resistance
    • 19. De Fronzo, R. A., J. D. Tobin & R. Andres. 1979. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 237: E214-E223.
    • (1979) Am. J. Physiol. , vol.237
    • De Fronzo, R.A.1    Tobin, J.D.2    Andres, R.3
  • 20
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and B-cell function from fasting plasma glucose and insulin concentrations in man
    • 20. Matthews, D., J. Hosker, A. Rudenski, et al. 1985. Homeostasis model assessment: insulin resistance and B-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.1    Hosker, J.2    Rudenski, A.3
  • 21
    • 0025646637 scopus 로고
    • Determinants of estimated insulin resistance and B-cell function in Indian, Creole and Chinese Mauritians
    • 21. Dowse, G., H. Qin, V. Collins, et al. 1990. Determinants of estimated insulin resistance and B-cell function in Indian, Creole and Chinese Mauritians. Diabetes Res. Clin. Practice 10: 265-279.
    • (1990) Diabetes Res. Clin. Practice , vol.10 , pp. 265-279
    • Dowse, G.1    Qin, H.2    Collins, V.3
  • 22
    • 0031775895 scopus 로고    scopus 로고
    • Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk
    • 22. Leyva, F., I. F. Godsland, M. Ghatei, et al. 1997. Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk. Arterioscler. Thromb. Vasc. Biol. 18: 928-933.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.18 , pp. 928-933
    • Leyva, F.1    Godsland, I.F.2    Ghatei, M.3
  • 23
    • 0030056807 scopus 로고    scopus 로고
    • Small, dense low density lipoproteins, the insulin resistance syndrome and noninsulin-dependent diabetes
    • 23. Austin, M. A. & K. L. Edwards. 1996. Small, dense low density lipoproteins, the insulin resistance syndrome and noninsulin-dependent diabetes. Curr. Opin. Lipidol. 7(3): 167-171.
    • (1996) Curr. Opin. Lipidol. , vol.7 , Issue.3 , pp. 167-171
    • Austin, M.A.1    Edwards, K.L.2
  • 24
    • 0028170620 scopus 로고
    • Multivariate analysis of the insulin resistance syndrome in women
    • 24. Edwards, K. L., M. A. Austin, B. Newman, et al. 1994. Multivariate analysis of the insulin resistance syndrome in women. Arterioscler. Thromb. 14(12): 1940-1945.
    • (1994) Arterioscler. Thromb. , vol.14 , Issue.12 , pp. 1940-1945
    • Edwards, K.L.1    Austin, M.A.2    Newman, B.3
  • 25
    • 0032008526 scopus 로고    scopus 로고
    • Factors of the insulin resistance syndrome in nondiabetic and diabetic elderly Japanese-American men
    • 25. Edwards, K. L., C. M. Burchfiel, D. S. Sharp, et al. 1998. Factors of the insulin resistance syndrome in nondiabetic and diabetic elderly Japanese-American men. Am. J. Epidemiol. 147(5): 441-447.
    • (1998) Am. J. Epidemiol. , vol.147 , Issue.5 , pp. 441-447
    • Edwards, K.L.1    Burchfiel, C.M.2    Sharp, D.S.3
  • 26
    • 0030840420 scopus 로고    scopus 로고
    • Risk variable clustering in the insulin resistance syndrome. The Framingham Offspring Study
    • 26. Meigs, J. B., R. B. D'Agostino, Sr., P. W. Wilson, et al. 1997. Risk variable clustering in the insulin resistance syndrome. The Framingham Offspring Study. Diabetes 46(10): 1594-1600.
    • (1997) Diabetes , vol.46 , Issue.10 , pp. 1594-1600
    • Meigs, J.B.1    D'Agostino R.B., Sr.2    Wilson, P.W.3
  • 27
    • 3543110722 scopus 로고    scopus 로고
    • Risk factor clustering in the insulin resistance syndrome. The Strong Heart Study
    • 27. Gray, R. S., R. R. Fabsitz, L. D. Cowan, et al. 1998. Risk factor clustering in the insulin resistance syndrome. The Strong Heart Study. Am. J. Epidemiol. 148(9): 869-878.
    • (1998) Am. J. Epidemiol. , vol.148 , Issue.9 , pp. 869-878
    • Gray, R.S.1    Fabsitz, R.R.2    Cowan, L.D.3
  • 28
    • 4243963793 scopus 로고    scopus 로고
    • Insulin links metabolic syndrome components in non-diabetic mauritians
    • Abstr.
    • 28. Hodge, A. M., M. DeCourten, P. Z. Zimmet et al. 1998. Insulin links metabolic syndrome components in non-diabetic Mauritians. Diabetes 47(Suppl. 1): A150 (Abstr.).
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Hodge, A.M.1    DeCourten, M.2    Zimmet, P.Z.3
  • 29
    • 0031770455 scopus 로고    scopus 로고
    • Endotheliopathy precedes Type 2 diabetes
    • 29. Tooke, J. E. 1998. Endotheliopathy precedes Type 2 diabetes. Diabetes Care 21: 2047-2048.
    • (1998) Diabetes Care , vol.21 , pp. 2047-2048
    • Tooke, J.E.1
  • 30
    • 0025780331 scopus 로고
    • Hyperinsulinaemia: The key feature of a cardiovascular and metabolic syndrome
    • 30. Ferrannini, E., S. M. Haffner, B. D. Mitchell, et al. 1991. Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome. Diabetologia 34: 416-422.
    • (1991) Diabetologia , vol.34 , pp. 416-422
    • Ferrannini, E.1    Haffner, S.M.2    Mitchell, B.D.3
  • 31
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • 31. Zhang, Y., R. Proenca, M. Maffei, et al. 1994. Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432.
    • (1994) Nature , vol.372 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3
  • 32
    • 0029066265 scopus 로고
    • Effects of the obese gene product on body weight regulation in ob/ob mice
    • 32. Pelleymounter, M., M. Cullen, M. Baker, et al. 1995. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269: 540-543.
    • (1995) Science , vol.269 , pp. 540-543
    • Pelleymounter, M.1    Cullen, M.2    Baker, M.3
  • 33
    • 0030028959 scopus 로고    scopus 로고
    • Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (Leptin) receptor
    • 33. Chua, S. C., Jr., W. K. Chung, X. S. Wu-Peng, et al. 1996. Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (Leptin) receptor. Science 271: 994-996.
    • (1996) Science , vol.271 , pp. 994-996
    • Chua S.C., Jr.1    Chung, W.K.2    Wu-Peng, X.S.3
  • 35
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • 35. Maffei, M., J. Halaas, E. Ravussin, et al. 1995. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1(11): 1155-1161.
    • (1995) Nat. Med. , vol.1 , Issue.11 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3
  • 36
    • 13344295079 scopus 로고    scopus 로고
    • Serum immunoreactive-leptin concentrations in normal-weight and obese humans
    • 36. Considine, R. V., M. K. Sinha, M. L. Heiman, et al. 1996. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N. Engl. J. Med. 334: 292-295.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 292-295
    • Considine, R.V.1    Sinha, M.K.2    Heiman, M.L.3
  • 37
    • 10544220841 scopus 로고    scopus 로고
    • Serum leptin concentration, obesity, and insulin resistance in Western Samoans: Cross sectional study
    • 37. Zimmet, P., A. Hodge, M. Nicolson, et al. 1996. Serum leptin concentration, obesity, and insulin resistance in Western Samoans: cross sectional study. Br. Med. J. 313: 965-969.
    • (1996) Br. Med. J. , vol.313 , pp. 965-969
    • Zimmet, P.1    Hodge, A.2    Nicolson, M.3
  • 38
    • 3042715083 scopus 로고    scopus 로고
    • Is there a relationship between leptin and insulin sensitivity independent of obesity? A population-based study in the Indian Ocean nation of Mauritius
    • 38. Zimmet, P. Z., V. R. Collins, M. P. De Courten, et al. 1998. Is there a relationship between leptin and insulin sensitivity independent of obesity? A population-based study in the Indian Ocean nation of Mauritius. Int. J. Obesity. 21: 171-177.
    • (1998) Int. J. Obesity , vol.21 , pp. 171-177
    • Zimmet, P.Z.1    Collins, V.R.2    De Courten, M.P.3
  • 39
    • 0032568376 scopus 로고    scopus 로고
    • Life without leptin
    • 39. O'Rahilly, S. 1998. Life without leptin. Nature 392: 330-331.
    • (1998) Nature , vol.392 , pp. 330-331
    • O'Rahilly, S.1
  • 40
    • 0032492453 scopus 로고    scopus 로고
    • Leptin
    • 40. Auwerx, J. & B. Staels. 1998. Leptin. Lancet 351: 737-742.
    • (1998) Lancet , vol.351 , pp. 737-742
    • Auwerx, J.1    Staels, B.2
  • 41
    • 0033016933 scopus 로고    scopus 로고
    • Is fasting leptin associated with insulin resistance among nondiabetic persons? The Miami Community Health Study
    • 41. Donahue, R. P., P. Zimmet, J. A. Bean, et al. 1999. Is fasting leptin associated with insulin resistance among nondiabetic persons? The Miami Community Health Study. Diabetes Care 22: 1092-1096.
    • (1999) Diabetes Care , vol.22 , pp. 1092-1096
    • Donahue, R.P.1    Zimmet, P.2    Bean, J.A.3
  • 42
    • 0030976609 scopus 로고    scopus 로고
    • Leptin concentrations and insulin sensitivity in normoglycemic men
    • 42. Haffner, S. M., H. Miettinen, L. Mykkänen, et al. 1997. Leptin concentrations and insulin sensitivity in normoglycemic men. Int. J. Obesity 21: 393-399.
    • (1997) Int. J. Obesity , vol.21 , pp. 393-399
    • Haffner, S.M.1    Miettinen, H.2    Mykkänen, L.3
  • 43
    • 0032788234 scopus 로고    scopus 로고
    • Combination of polymorphisms in OB-R and the OB gene associated with insulin resistance in Nauruan males
    • In press
    • 43. De Silva, A. M., K. R. Walder, T. J. Aitman, et al. 1999. Combination of polymorphisms in OB-R and the OB gene associated with insulin resistance in Nauruan males. Int. J. Obesity. In press.
    • (1999) Int. J. Obesity
    • De Silva, A.M.1    Walder, K.R.2    Aitman, T.J.3
  • 44
    • 0031937128 scopus 로고    scopus 로고
    • Increased plasma leptin levels are associated with fat accumulation in Japanese Americans
    • 44. Chessler, S. D., W. Y. Fujimoto, J. B. Shofer, et al. 1998. Increased plasma leptin levels are associated with fat accumulation in Japanese Americans. Diabetes 47: 239-243.
    • (1998) Diabetes , vol.47 , pp. 239-243
    • Chessler, S.D.1    Fujimoto, W.Y.2    Shofer, J.B.3
  • 45
    • 0028292767 scopus 로고
    • A cross-sectional and short-term longitudinal characterization of NIDDM in the sand rat
    • 45. Barnett, M., G. R. Collier, F. M. Collier, et al. 1994. A cross-sectional and short-term longitudinal characterization of NIDDM in the sand rat. Diabetologia 37: 671-676.
    • (1994) Diabetologia , vol.37 , pp. 671-676
    • Barnett, M.1    Collier, G.R.2    Collier, F.M.3
  • 46
    • 0028849384 scopus 로고
    • Basal glucose turnover in Psammomys obesus. An animal model of type 2 (non-insulin-dependent) diabetes mellitus
    • 46. Habito, R., M. Barbett, A. Yamamoto, et al. 1995. Basal glucose turnover in Psammomys obesus. An animal model of type 2 (non-insulin-dependent) diabetes mellitus. Acta Diabetol. 32: 187-192.
    • (1995) Acta Diabetol. , vol.32 , pp. 187-192
    • Habito, R.1    Barbett, M.2    Yamamoto, A.3
  • 47
    • 0030670427 scopus 로고    scopus 로고
    • Development of obesity and insulin resistance in the Israeli Sand rat (Psammomys obesus): Does leptin play a role?
    • 47. Collier, G. R., A. De Silva, A. Sanigorski, et al. 1997. Development of obesity and insulin resistance in the Israeli Sand rat (Psammomys obesus): Does leptin play a role? Ann. N.Y. Acad. Sci. 827: 50-63.
    • (1997) Ann. N.Y. Acad. Sci. , vol.827 , pp. 50-63
    • Collier, G.R.1    De Silva, A.2    Sanigorski, A.3
  • 48
    • 0031472070 scopus 로고    scopus 로고
    • Ob (obese) gene expression and leptin levels in Psammomys obesus
    • 48. Walder, K., M. Willet, P. Zimmet, et al. 1997. Ob (obese) gene expression and leptin levels in Psammomys obesus. Biochem. Biophys. Acta 1354: 272-278.
    • (1997) Biochem. Biophys. Acta , vol.1354 , pp. 272-278
    • Walder, K.1    Willet, M.2    Zimmet, P.3
  • 49
    • 0009637493 scopus 로고    scopus 로고
    • Leptin administration has no effect on food intake, body weight or diabetic status in a multigenic model of obesity: Psammomys obesus
    • 49. Walder, K., P. Lewandowski, A. Sanigorski, et al. 1999. Leptin administration has no effect on food intake, body weight or diabetic status in a multigenic model of obesity: Psammomys obesus. Int. J. Obesity 22: 1-7.
    • (1999) Int. J. Obesity , vol.22 , pp. 1-7
    • Walder, K.1    Lewandowski, P.2    Sanigorski, A.3
  • 50
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • 50. Campfield, L. A., F. J. Smith, Y. Guisez, et al. 1995. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269: 546-549.
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3
  • 51
    • 70349566593 scopus 로고
    • Diabetes mellitus: A thrifty genotype rendered detrimental by 'progress'?
    • 51. Neel, J. V. 1962. Diabetes mellitus: a thrifty genotype rendered detrimental by 'progress'? Am. J. Hum. Genet. 14: 353-362.
    • (1962) Am. J. Hum. Genet. , vol.14 , pp. 353-362
    • Neel, J.V.1
  • 52
    • 0027533329 scopus 로고
    • The thrifty genotype in non-insulin-dependent diabetes. The hypothesis survives
    • 52. Dowse, G. & P. Zimmet. 1993. The thrifty genotype in non-insulin-dependent diabetes. The hypothesis survives. Br. Med. J. 306: 532-533.
    • (1993) Br. Med. J. , vol.306 , pp. 532-533
    • Dowse, G.1    Zimmet, P.2
  • 53
    • 0030039272 scopus 로고    scopus 로고
    • Abnormal splicing of the leptin receptor in diabetic mice
    • 53. Lee, G. H., R. Proenca, J. M. Montez, et al. 1996. Abnormal splicing of the leptin receptor in diabetic mice. Nature 379: 632-635.
    • (1996) Nature , vol.379 , pp. 632-635
    • Lee, G.H.1    Proenca, R.2    Montez, J.M.3
  • 54
    • 0029860791 scopus 로고    scopus 로고
    • Modulation of insulin activities by leptin
    • 54. Cohen, B., D. Novick & M. Rubinstein. 1997. Modulation of insulin activities by leptin. Science 274: 1185-1188.
    • (1997) Science , vol.274 , pp. 1185-1188
    • Cohen, B.1    Novick, D.2    Rubinstein, M.3
  • 55
    • 0030898516 scopus 로고    scopus 로고
    • Direct antidiabetic effects of leptin through triglyceride depletion of tissues
    • 55. Shimanukuro, M., K. Koyama, G. Chen, et al. 1997. Direct antidiabetic effects of leptin through triglyceride depletion of tissues. Proc. Natl. Acad. Sci. USA 94: 4637-4641.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4637-4641
    • Shimanukuro, M.1    Koyama, K.2    Chen, G.3
  • 56
    • 0030782649 scopus 로고    scopus 로고
    • Leptin inhibits insulin binding in isolated rat adipocytes
    • 56. Walder, K., A. Pilippis, S. Clark, et al. 1997. Leptin inhibits insulin binding in isolated rat adipocytes. J. Endocrinol. 155: R5-R7.
    • (1997) J. Endocrinol. , vol.155
    • Walder, K.1    Pilippis, A.2    Clark, S.3
  • 57
    • 0030965884 scopus 로고    scopus 로고
    • Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
    • 57. Emilsson, V., Y.-L. Liu, M. A. Cawthorne, et al. Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 46: 313-336.
    • Diabetes , vol.46 , pp. 313-336
    • Emilsson, V.1    Liu, Y.-L.2    Cawthorne, M.A.3
  • 58
    • 15444339427 scopus 로고    scopus 로고
    • Obesity, diabetes and the central nervous system
    • 58. Porte, D., R. J. Seeley, S. C. Woods, et al. 1998. Obesity, diabetes and the central nervous system. Diabetologia 41: 863-881.
    • (1998) Diabetologia , vol.41 , pp. 863-881
    • Porte, D.1    Seeley, R.J.2    Woods, S.C.3
  • 59
    • 0030884022 scopus 로고    scopus 로고
    • Endothelial dysfunction: Cause of the insulin resistance syndrome
    • 59. Pinkney, J. H., C. D., Stehouwer, S. W. Coppack, et al. 1997. Endothelial dysfunction: cause of the insulin resistance syndrome. Diabetes 46(Suppl. 2): S9-13.
    • (1997) Diabetes , vol.46 , Issue.SUPPL. 2
    • Pinkney, J.H.1    Stehouwer, C.D.2    Coppack, S.W.3
  • 60
    • 0027381832 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus
    • 60. Johnstone, M. T., S. J. Creager, K. M. Scales, et al. 1993. Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. Circulation 88(6): 2510-2516.
    • (1993) Circulation , vol.88 , Issue.6 , pp. 2510-2516
    • Johnstone, M.T.1    Creager, S.J.2    Scales, K.M.3
  • 61
    • 0026684462 scopus 로고
    • Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus
    • 61. McVeigh, G. E., G. M. Brennan, G. D. Johnston, et al. 1992. Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 35(8): 771-776.
    • (1992) Diabetologia , vol.35 , Issue.8 , pp. 771-776
    • McVeigh, G.E.1    Brennan, G.M.2    Johnston, G.D.3
  • 62
    • 0029977757 scopus 로고    scopus 로고
    • Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance
    • 62. Steinberg, H. O., H. Chaker, R. Leaming, et al. 1996. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J. Clin. Invest. 97(11): 2601-2610.
    • (1996) J. Clin. Invest. , vol.97 , Issue.11 , pp. 2601-2610
    • Steinberg, H.O.1    Chaker, H.2    Leaming, R.3
  • 63
    • 0026451015 scopus 로고
    • Impaired endothelium-dependent vasodilation of forearm resistance vessels in hypercholesterolaemia
    • 63. Chowienczyk, P. J., G. F. Watts, J. R. Cockcroft, et al. 1992. Impaired endothelium-dependent vasodilation of forearm resistance vessels in hypercholesterolaemia. Lancet 340(8833): 1430-1432.
    • (1992) Lancet , vol.340 , Issue.8833 , pp. 1430-1432
    • Chowienczyk, P.J.1    Watts, G.F.2    Cockcroft, J.R.3
  • 64
    • 0030729184 scopus 로고    scopus 로고
    • Endothelial dysfunction is associated with cholesterol levels in the high normal range in humans
    • 64. Steinberg, H. O., B. Bayazeed, G. Hook, et al. 1997. Endothelial dysfunction is associated with cholesterol levels in the high normal range in humans. Circulation 96(10): 3287-3293.
    • (1997) Circulation , vol.96 , Issue.10 , pp. 3287-3293
    • Steinberg, H.O.1    Bayazeed, B.2    Hook, G.3
  • 65
    • 0028275313 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with essential hypertension: Evidence that the abnormality is not at the muscarinic receptor level
    • 65. Panza, J. A., P. R. Casino, C. M. Kilcoyne, et al. 1994. Impaired endothelium-dependent vasodilation in patients with essential hypertension: evidence that the abnormality is not at the muscarinic receptor level. J. Am. Coll. Cardiol. 23(7): 1610-1616.
    • (1994) J. Am. Coll. Cardiol. , vol.23 , Issue.7 , pp. 1610-1616
    • Panza, J.A.1    Casino, P.R.2    Kilcoyne, C.M.3
  • 66
    • 0027236046 scopus 로고
    • Associations of factor VIII and Von Willebrand factor with age, race, sex, and risk factors for atherosclerosis. The Atherosclerosis Risk in Communities (Aric) Study
    • 66. Conlan, M. G., A. R. Folsom, A. Finch, et al. 1993. Associations of factor VIII and von Willebrand factor with age, race, sex, and risk factors for atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study. Thromb. Haemostasis 70(3): 380-385.
    • (1993) Thromb. Haemostasis , vol.70 , Issue.3 , pp. 380-385
    • Conlan, M.G.1    Folsom, A.R.2    Finch, A.3
  • 67
    • 0031054463 scopus 로고    scopus 로고
    • Nitric oxide synthase: Role in the genesis of vascular disease
    • 67. Cooke, J. P. & V. J. Dzau. 1997. Nitric oxide synthase: role in the genesis of vascular disease. Annu. Rev. Med. 48: 489-509.
    • (1997) Annu. Rev. Med. , vol.48 , pp. 489-509
    • Cooke, J.P.1    Dzau, V.J.2
  • 68
    • 0032485927 scopus 로고    scopus 로고
    • Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo
    • 68. Williams, S. B., A. B. Goldfine, F. K. Timimi, et al. 1998. Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo. Circulation 97(17): 1695-1701.
    • (1998) Circulation , vol.97 , Issue.17 , pp. 1695-1701
    • Williams, S.B.1    Goldfine, A.B.2    Timimi, F.K.3
  • 69
    • 0031793051 scopus 로고    scopus 로고
    • Impaired endothelium-dependent vasodilation in women with previous gestational diabetes
    • 69. Anastasiou, E., J. P. Lekakism, M. Alevizaki, et al. 1998. Impaired endothelium-dependent vasodilation in women with previous gestational diabetes. Diabetes Care 21(12): 2111-2115.
    • (1998) Diabetes Care , vol.21 , Issue.12 , pp. 2111-2115
    • Anastasiou, E.1    Lekakism, J.P.2    Alevizaki, M.3
  • 70
    • 0029819733 scopus 로고    scopus 로고
    • Chronic hyperglycemia impairs endothelial function and insulin sensitivity via different mechanisms in insulin-dependent diabetes mellitus
    • 70. Makimattila, S., A. Virkamaki, P. H. Groop, et al. 1996. Chronic hyperglycemia impairs endothelial function and insulin sensitivity via different mechanisms in insulin-dependent diabetes mellitus. Circulation 94(6): 1276-1282.
    • (1996) Circulation , vol.94 , Issue.6 , pp. 1276-1282
    • Makimattila, S.1    Virkamaki, A.2    Groop, P.H.3
  • 71
    • 0030763350 scopus 로고    scopus 로고
    • Flow-mediated dilation in 9-to 11-year-old children: The influence of intrauterine and childhood factors
    • 71. Leeson, C. P., P. H. Whincup, D. G. Cook, et al. 1997. Flow-mediated dilation in 9-to 11-year-old children: the influence of intrauterine and childhood factors. Circulation 96(7): 2233-2238.
    • (1997) Circulation , vol.96 , Issue.7 , pp. 2233-2238
    • Leeson, C.P.1    Whincup, P.H.2    Cook, D.G.3
  • 72
    • 0028113927 scopus 로고
    • Nitric oxide release accounts for insulin's vascular effects in humans
    • 72. Scherrer, U., D. Randin, P. Vollenweider, et al. 1994. Nitric oxide release accounts for insulin's vascular effects in humans. J. Clin. Invest. 94(6): 2511-2515.
    • (1994) J. Clin. Invest. , vol.94 , Issue.6 , pp. 2511-2515
    • Scherrer, U.1    Randin, D.2    Vollenweider, P.3
  • 73
    • 0028030813 scopus 로고
    • Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release
    • 73. Steinberg, H. O., G. Brechtel, A. Johnson, et al. 1994. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J. Clin. Invest. 94(3): 1172-1179.
    • (1994) J. Clin. Invest. , vol.94 , Issue.3 , pp. 1172-1179
    • Steinberg, H.O.1    Brechtel, G.2    Johnson, A.3
  • 74
    • 0029119084 scopus 로고
    • Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans
    • 74. Baron, A. D., H. O. Steinberg, H. Chaker, et al. 1995. Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans. J. Clin. Invest. 96(2): 786-792.
    • (1995) J. Clin. Invest. , vol.96 , Issue.2 , pp. 786-792
    • Baron, A.D.1    Steinberg, H.O.2    Chaker, H.3
  • 75
    • 0031920445 scopus 로고    scopus 로고
    • Insulin-induced vasodilatation: Physiology or pharmacology?
    • 75. Yki-Jarvinen, H. & T. Utriainen. 1998. Insulin-induced vasodilatation: physiology or pharmacology? Diabetologia 41: 369-379.
    • (1998) Diabetologia , vol.41 , pp. 369-379
    • Yki-Jarvinen, H.1    Utriainen, T.2
  • 77
    • 0009556904 scopus 로고    scopus 로고
    • Acetylation stimulating protein (ASP), an adipocyte autocrine: New directions
    • In press
    • 77. Cianflone, K., M. Maslowska & A. D. Sniderman. 1998. Acetylation stimulating protein (ASP), an adipocyte autocrine: new directions. Cell Dev. Biol. In press.
    • (1998) Cell Dev. Biol.
    • Cianflone, K.1    Maslowska, M.2    Sniderman, A.D.3
  • 78
    • 0030707883 scopus 로고    scopus 로고
    • Obesity and the adipocyte. Acetylation stimulating protein and the adipocyte
    • 78. Cianflone, K. 1997. Obesity and the adipocyte. Acetylation stimulating protein and the adipocyte. J. Endocrinol. 155: 203-206.
    • (1997) J. Endocrinol. , vol.155 , pp. 203-206
    • Cianflone, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.