IGF-I downregulates resistin gene expression and protein secretion

American Journal of Physiology - Endocrinology and Metabolism

Volumn 288, Issue 5 51-5, 2005, Pages

  Chen, Yen Hang ^a   Hung, Pei Fang ^a   Kao, Yung Hsi ^a  

^a NATIONAL CENTRAL UNIVERSITY   (Taiwan)

Author keywords

3T3 L1; Adipocytes; Insulin like growth factor; Mitogen activated protein kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYCLOHEXIMIDE; DACTINOMYCIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; RECEPTOR ANTIBODY; RESISTIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BODY WEIGHT; CELL DIFFERENTIATION; CELL STRAIN 3T3; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; IC 50; INSULIN RESISTANCE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN STABILITY; RNA SYNTHESIS; SIGNAL TRANSDUCTION; TIME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3-L1 CELLS; ADIPOCYTES; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HORMONES, ECTOPIC; INSULIN-LIKE GROWTH FACTOR I; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; RESISTIN; SIGNAL TRANSDUCTION;

EID: 17444421501     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00325.2004     Document Type: Article

References (51)

1. Alessi DR, Cuenda A, Cohen P, Dudley DT, and Saltiel AR. PD98059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270: 27489-27494, 1995.
2. Arco AD, Peralta S, Carrascosa JM, Ros M, Andres A, and Arribas C. Alternative splicing generates a novel non-secretable resistin isoform in Wistar rats. FEBS Lett 555: 243-249, 2003.
3. Banerjee RR and Lazar MA. Resistin: molecular history and prognosis. J Mol Med 81: 218-226, 2003.
4. Banerjee RR, Rangwala SM, Shapiro JS, Rich AS, Rhoades B, Qi Y, Wang J, Rajala MW, Pocai A, Scherer PE, Steppan CM, Ahima RS, Obici S, Rossetti L, and Lazar MA. Regulation of fasted blood glucose by resistin. Science 303: 1195-1198, 2004.
5. Becker WM, Kleinsmith LJ, and Hardin J. The World of the Cell. San Francisco, CA: Pearson Education, 2003.
6. Boney CM, Sekimoto H, Gruppuso PA, and Frackelton AR. Src family tyrosine kinases participate in insulin-like growth factor 1 mitogenic signaling in 3T3-L1 cells. Cell Growth Differ 12: 379-386, 2001.
7. Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
8. Brunn GJ, Sabers WJ, Wiederrecht G, Lawrence JC, and Abraham RT. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J 15: 5256-5267, 1996.
9. Cepica S, Rohrer GA, Masopust M, Kubickova S, Musilova P, and Rubes J. Partial cloning, cytogenetic and linkage mapping of the porcine resistin (RSTN) gene. Anim Genet 33: 381-383, 2002.
10. Degawa-Yamauchi M, Bovenkerk J, Juliar BE, Watson W, Kerr K, Jones R, Zhu Q, and Considine RV. Serum resistin (FIZZ3) protein is increased in obese humans. J Clin Endocrinol Metab 88: 5452-5455, 2003.
11. Delhanty PJ, Mesotten D, Mcdougall F, and Baxter RC. Growth hormone rapidly induces resistin gene expression in white adipose tissue of spontaneous dwarf (SDR) rats. Endocrinology 143: 2445-24448, 2002.
12. Eilertson CD and Sheridan MA. Pancreatic somatostatin-14 and somatostatin-25 release in rainbow trout is stimulated by glucose and arginine. Am J Physiol Regul Integr Comp Physiol 269: R1017-R1023, 1995.
13. Engelman JA, Lisanti MP, and Scherer PE. Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. J Biol Chem 273: 32111-32120, 1998.
14. Engert JC, Vohl MC, Williams SM, Lepage P, Loredo-Osti JC, Faith J, Dore C, Renaud Y, Burtt NP, Villeneuve A, Hirschhorn JN, Altshuler D, Groop LC, Despres JP, Gaudet D, and Hudson TJ. 5′-Flanking variants of resistin are associated with obesity. Diabetes 51: 1629-2002, 2002.
15. Fain JN, Cheema PS, Bahouth SW, and Hiler ML. Resistin release by human adipose tissue explants in primary culture. Biochem Biophys Res Commun 300: 674-678, 2003.
16. Fasshauer M, Klein J, Neumann S, Eszlinger M, and Paschke R. Tumor necrosis factor α is a negative regulator of resistin gene expression and secretion in 3T3-L1 adipocytes. Biochem Biophys Res Commun 288: 1027-1031, 2001.
17. Fasshauer M and Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia 46: 1594-1603, 2003.
18. Felipe F, Bonet ML, Ribot J, and Palou A. Modulation of resistin expression by retinoic acid and vitamin A status. Diabetes 53: 882-889, 2004.
19. Ghosh S, Singh AK, Aruna B, Mukhopadhyay S, and Ehtesham NZ. The genomic organization of mouse resistin reveals major differences from the human resistin: functional implications. Gene 305: 27-34, 2003.
20. Gual P, Baron V, Lequoy V, and Obberghen EV. Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor-1 receptor. Endocrinology 139: 884-893, 1998.
21. Gutierrez J, Parrizas M, Maestro MA, Navarro I, and Plisetskaya EM. Insulin and IGF-I binding and tyrosine kinase activity in fish heart. J Endocrinol 146: 35-44, 1995.
22. Hana V, Silha JV, Justova V, Lacinova Z, Stepan JJ, and Murphy LJ. The effects of GH replacement in adult GH-deficient patients: changes in body composition without concomitant changes in the adipokines and insulin resistance. Clin Endocrinol (Oxf) 60: 442-450, 2004.
23. Hartman HB, Hu X, Tyler KX, Dalal CK, and Lazar MA. Mechanisms regulating adipocyte expression of resistin. J Biol Chem 277: 19754-19761, 2002.
24. Haugen F, Jorgensen A, Drevon CA, and Trayhurn P. Inhibition by insulin of resistin gene expression in 3T3-L1 adipocytes. FEBS Lett 507: 105-108, 2001.
25. Kao YH, Hippakka RA, and Liao S. Modulation of obesity by a green tea catechin. Am J Clin Nutr 72: 1232-1241, 2000.
26. Kawashima J, Tsuruzoe K, Motoshima H, Shirakami A, Sakai K, Hirashima Y, Toyonaga T, and Araki E. Insulin down-regulates resistin mRNA through the synthesis of protein(s) that could accelerate the degradation of resistin mRNA in 3T3-L1 adipocytes. Diabetologia 46: 231-240, 2003.
27. Kim KH, Lee K, Moon YS, and Sul HS. A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation. J Biol Chem 276: 11252-11256, 2001.
28. Kim KH, Zhao L, Moon Y, Kang C, and Sul HS. Dominant inhibitory adipocyte-specific secretory factor (ADSF)/resistin enhances adipogenesis and improves insulin sensitivity. Proc Natl Acad Sci USA 101: 6780-6785, 2004.
29. Kokontis JM, Hay N, and Liao S. Progression of LNCaP prostate tumor cells during androgen deprivation: hormone-independent growth, repression of proliferation by androgen, and role for p27Kip1 in androgen-induced cell cycle arrest. Mol Endocrinol 12: 941-953, 1998.
30. Maebuchi M, Machidori M, Urade R, Ogawa T, and Moriyama T. Low resistin levels in adipose tissues and serum in high-fat fed mice and genetically obese mice: development of an ELISA system for quantification of resistin. Arch Biochem Biophys 416: 164-170, 2003.
31. Meyer GE, Shelden E, Kim B, and Feldman EL. Insulin-like growth factor I stimulates motility in human neuroblastoma cells. Oncogene 20: 7542-7550, 2001.
32. Moon B, Kwan JJ, Duddy N, Sweeney G, and Begum N. Resistin inhibits glucose uptake in L6 cells independently of changes in insulin signaling and GLUT4 translocation. Am J Physiol Endocrinol Metab 285: E106-E115, 2003.
33. Nogueiras R, Gualillo O, Caminos JE, Casanueva FF, and Dieguez C. Regulation of resistin by gonadal, thyroid hormone, and nutritional status. Obes Res 11: 408-414, 2003.
34. Nohira T, Nagao K, Kameyama K, Nakai H, Fukumine N, Okabe K, Kitano S, and Hisatomi H. Identification of an alternative splicing transcript for the resistin gene and distribution of its mRNA in human tissue. Eur J Endocrinol 151: 151-154, 2004.
35. Oliver P, Pico C, Serra F, and Palou A. Resistin expression in different adipose tissue depots during rat development. Mol Cell Biochem 252: 397-400, 2003.
36. Pizzuti A, Argiolas A, Paola RD, Baratta R, Rausea A, Bozzali M, Vigneri R, Dallapiccola B, Trischitta V, and Frittitta L. An ATG repeat in the 3′-untranslated region of the human resistin gene is associated with a decreased risk of insulin resistance. J Clin Endocrinol Metab 87: 4403-4406, 2002.
37. Ramirez-Zacarias JL, Castro-Munozledo F, and Kuri-Harcuch W. Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O. Histochemistry 97: 493-497, 1992.
38. Reischl U, Ruger R, and Kessler C. Nonradioactive labeling and high sensitive detection of PCR products. Mol Biotechnol 1: 229-240, 1994.
39. Rosenfeld RG and Roberts CT. The IGF System: Molecular Biology, Physiology, and Clinical Applications. Totowa, NJ: Humana, 1999.
40. Ross J. Control of messenger RNA stability in higher eukaryotes. Trends Genet 12: 171-175, 1996.
41. Seo JB, Noh MJ, Yoo EJ, Park SY, Park J, Lee IK, Park SD, and Kim JB. Functional characterization of the human resistin promoter with adipocyte determination-and differentiation-dependent factor 1/sterol regulatory element binding protein 1c and CCAAT enhancer binding protein-α. Mol Endocrinol 17: 1522-1533, 2003.
42. Shojima N, Sakoda H, Ogihara T, Fujishiro M, Katagiri H, Anai M, Onishi Y, Ono H, Inukai K, Abe M, Fukushima Y, Kikuchi M, and Oka Y, and Asano T. Humoral regulation of resistin expression in 3T3-L1 and mouse adipose cells. Diabetes 51: 1737-1744, 2002.
43. Song RX, Barnes CJ, Zhang Z, Bao Y, Kumar R, and Santen RJ. The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor a to the plasma membrane. Proc Natl Acad Sci USA 101: 2076-2081, 2004.
44. Song H, Shojima N, Sakoda H, Ogihara T, Fujishiro M, Katagiri H, Anai M, Onishi Y, Ono H, Inukai K, Fukushima Y, Kikuchi M, Shimano H, Yamada N, Oka Y, and Asano T. Resistin is regulated by C/EBPs, PPARs, and signal-transducing molecules. Biochem Biophys Res Commun 299: 291-298, 2002.
45. Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS, and Lazar MA. The hormone resistin links obesity to diabetes. Nature 409: 307-312, 2001.
46. Steppan CM, Brown EJ, Wright CM, Bhat S, Banerjee RR, Dai CY, Enders GH, Silberg DG, Wen X, Wu GD, and Lazar MA. A family of tissue-specific resistin-like molecules. Proc Natl Acad Sci USA 98: 502-506, 2001.
47. Verma S, Li SH, Wang CH, Fedak PWM, Li RK, Weisel RD, and Mickle DAG. Resistin promotes endothelial cell activation further evidence of adipokine-endothelial interaction. Circulation 108: 736-740, 2003.
48. Viengchareun S, Zennaro M, Tallec LP, and Lombes M. Brown adipocytes are novel sites of expression and regulation of adiponectin and resistin. FEBS Lett 532: 345-350, 2002.
49. Way JM, Gorgun CZ, Tong Q, Uysal KT, Brown KK, Harrington WW, Oliver WR, Willson TM, Kliewert SA, and Hotamisligil GS. Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor γ agonists. J Biol Chem 276: 25651-25653, 2001.
50. Youn BS, Yu KY, Park HJ, Lee NS, Min SS, Youn MY, Cho YM, Park YJ, Kim SY, Lee HK, and Park KS. Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus. J Clin Endocrinol Metab 89: 150-156, 2004.
51. Zhong Q, Lin CY, Clarke KJ, Kemppainen RJ, Schwartz DD, and Judd RL. Endothelin-1 inhibits resistin secretion in 3T3-L1 adipocytes. Biochem Biophys Res Commun 16: 383-387, 2002.