메뉴 건너뛰기




Volumn 39, Issue 3, 2005, Pages 237-242

Is adiponectin involved in the pathogenesis of nonalcoholic steatohepatitis? A preliminary human study

Author keywords

Adiponectin; Insulin resistance; Nonalcoholic steatohepatitis

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR; CYTOKINE RECEPTOR; HIGH DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 14144249423     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mcg.0000152747.79773.2f     Document Type: Article
Times cited : (87)

References (38)
  • 1
    • 0036176194 scopus 로고    scopus 로고
    • Update on nonalcoholic fatty liver disease
    • McCullough AJ. Update on nonalcoholic fatty liver disease. J Clin Gastroenterol. 2002;34:255-262.
    • (2002) J Clin Gastroenterol , vol.34 , pp. 255-262
    • McCullough, A.J.1
  • 2
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
    • Matteoni CA, Younossi ZM, Gramlich T, et al. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology. 1999;116:1413-1419.
    • (1999) Gastroenterology , vol.116 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Gramlich, T.3
  • 3
    • 0035085853 scopus 로고    scopus 로고
    • Clinical features and natural history of nonalcoholic steatosis syndromes
    • Falck-Ytter Y, Younossi ZM, Marchesini G, et al. Clinical features and natural history of nonalcoholic steatosis syndromes. Semin Liver Dis. 2001;21:17-26.
    • (2001) Semin Liver Dis , vol.21 , pp. 17-26
    • Falck-Ytter, Y.1    Younossi, Z.M.2    Marchesini, G.3
  • 4
    • 0036302288 scopus 로고    scopus 로고
    • Expanding the natural history of nonalcoholic steatohepatitis: From cryptogenic cirrhosis to hepatocellular carcinoma
    • Bugianesi E, Leone N, Vanni E, et al. Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology. 2002;123:134-140.
    • (2002) Gastroenterology , vol.123 , pp. 134-140
    • Bugianesi, E.1    Leone, N.2    Vanni, E.3
  • 5
    • 0035084699 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
    • Sanyal AJ, Campbell-Sargent C, Mirshahi F, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology. 2001;120:1183-1192.
    • (2001) Gastroenterology , vol.120 , pp. 1183-1192
    • Sanyal, A.J.1    Campbell-Sargent, C.2    Mirshahi, F.3
  • 6
    • 18244364864 scopus 로고    scopus 로고
    • NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome
    • Chitturi S, Abeygunasekera S, Farrell GC, et al. NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology. 2002;35:373-379.
    • (2002) Hepatology , vol.35 , pp. 373-379
    • Chitturi, S.1    Abeygunasekera, S.2    Farrell, G.C.3
  • 7
    • 0033231294 scopus 로고    scopus 로고
    • Association of nonalcoholic fatty liver disease with insulin resistance
    • Marchesini G, Brizi M, Morselli-Labate AM, et al. Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med. 1999;107:450-455.
    • (1999) Am J Med , vol.107 , pp. 450-455
    • Marchesini, G.1    Brizi, M.2    Morselli-Labate, A.M.3
  • 8
    • 0034799113 scopus 로고    scopus 로고
    • Ninety patients with nonalcoholic steatohepatitis: Insulin resistance, familial tendency, and severity of disease
    • Willner IR, Waters B, Patil SR, et al. Ninety patients with nonalcoholic steatohepatitis: insulin resistance, familial tendency, and severity of disease. Am J Gastroenterol. 2001;96:2957-2961.
    • (2001) Am J Gastroenterol , vol.96 , pp. 2957-2961
    • Willner, I.R.1    Waters, B.2    Patil, S.R.3
  • 9
    • 0041571837 scopus 로고    scopus 로고
    • Metabolic and anthropometric evaluation of insulin resistance in nondiabetic patients with nonalcoholic steatohepatitis
    • Chalasani N, Deeg MA, Persohn S, et al. Metabolic and anthropometric evaluation of insulin resistance in nondiabetic patients with nonalcoholic steatohepatitis. Am J Gastroenterol. 2003;98:1849-1855.
    • (2003) Am J Gastroenterol , vol.98 , pp. 1849-1855
    • Chalasani, N.1    Deeg, M.A.2    Persohn, S.3
  • 10
    • 1442355447 scopus 로고    scopus 로고
    • A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis
    • Promrat K, Lutchman G, Uwaifo GI, et al. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology. 2004;39:188-196.
    • (2004) Hepatology , vol.39 , pp. 188-196
    • Promrat, K.1    Lutchman, G.2    Uwaifo, G.I.3
  • 11
    • 0141532275 scopus 로고    scopus 로고
    • Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
    • Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, et al. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology. 2003;38:1008-1017.
    • (2003) Hepatology , vol.38 , pp. 1008-1017
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3
  • 12
    • 0037385387 scopus 로고    scopus 로고
    • Interim results of a pilot study demonstrating the early effects of the PPAR-gamma ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis
    • Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, et al. Interim results of a pilot study demonstrating the early effects of the PPAR-gamma ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis. J Hepatol. 2003;38:434-440.
    • (2003) J Hepatol , vol.38 , pp. 434-440
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3
  • 13
    • 0037794933 scopus 로고    scopus 로고
    • A randomized controlled pilot study of pioglitazone and vitamin E versus vitamin E for nonalcoholic steatohepatitis
    • Sanyal AJ, Contos MJ, et al. A randomized controlled pilot study of pioglitazone and vitamin E versus vitamin E for nonalcoholic steatohepatitis. Hepatology. 2002;36:382A.
    • (2002) Hepatology , vol.36
    • Sanyal, A.J.1    Contos, M.J.2
  • 14
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two 'hits?'
    • Day CP, James OF. Steatohepatitis: a tale of two 'hits?' Gastroenterology. 1998;114:842-845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 15
    • 0036211568 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: An agenda for clinical research
    • Younossi ZM, Diehl AM, Ong JP. Nonalcoholic fatty liver disease: an agenda for clinical research. Hepatology. 2002;35:746-752.
    • (2002) Hepatology , vol.35 , pp. 746-752
    • Younossi, Z.M.1    Diehl, A.M.2    Ong, J.P.3
  • 16
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
    • Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology. 2003;37: 1202-1219.
    • (2003) Hepatology , vol.37 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 18
    • 0037356826 scopus 로고    scopus 로고
    • The role of the novel adipocyte-derived hormone adiponectin in human disease
    • Diez JJ, Iglesias P. The role of the novel adipocyte-derived hormone adiponectin in human disease. Eur J Endocrinol. 2003;148:293-300.
    • (2003) Eur J Endocrinol , vol.148 , pp. 293-300
    • Diez, J.J.1    Iglesias, P.2
  • 19
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi T, Kamon J, Ito Y, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature. 2003;423:762-769.
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3
  • 20
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A, Wang Y, Keshaw H, et al. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest. 2003;112:91-100.
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3
  • 21
    • 0345059390 scopus 로고    scopus 로고
    • Insulin resistance and tissue repair: A 'fato-logical' phenomenon
    • Sanyal AJ. Insulin resistance and tissue repair: a 'fato-logical' phenomenon. Gastroenterology. 2003;125:1886-1889.
    • (2003) Gastroenterology , vol.125 , pp. 1886-1889
    • Sanyal, A.J.1
  • 22
    • 0842313004 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients
    • Bajaj M, Suraamornkul S, Piper P, et al. Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. J Clin Endocrinol Metab. 2004;89:200-206.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 200-206
    • Bajaj, M.1    Suraamornkul, S.2    Piper, P.3
  • 23
    • 10744228583 scopus 로고    scopus 로고
    • Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
    • Kamada Y, Tamura S, Kiso S, et al. Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology. 2003;125:1796-1807.
    • (2003) Gastroenterology , vol.125 , pp. 1796-1807
    • Kamada, Y.1    Tamura, S.2    Kiso, S.3
  • 24
    • 3042744737 scopus 로고    scopus 로고
    • Beyond insulin resistance in NASH: TNF-alpha or adiponectin?
    • Hui JM, Hodge A, Farrell GC, et al. Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology. 2004;40:46-54.
    • (2004) Hepatology , vol.40 , pp. 46-54
    • Hui, J.M.1    Hodge, A.2    Farrell, G.C.3
  • 25
    • 0142030040 scopus 로고    scopus 로고
    • Plasma adiponectin increases postprandially in obese, but not in lean, subjects
    • English PJ, Coughlin SR, Hayden K, et al. Plasma adiponectin increases postprandially in obese, but not in lean, subjects. Obes Res. 2003;11: 839-844.
    • (2003) Obes Res , vol.11 , pp. 839-844
    • English, P.J.1    Coughlin, S.R.2    Hayden, K.3
  • 26
    • 0037382071 scopus 로고    scopus 로고
    • Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
    • Musso G, Gambino R, De Michieli F, et al. Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology. 2003;37:909-916.
    • (2003) Hepatology , vol.37 , pp. 909-916
    • Musso, G.1    Gambino, R.2    De Michieli, F.3
  • 27
    • 0037369729 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis
    • Chalasani N, Gorski JC, Asghar MS, et al. Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis. Hepatology. 2003;37:544-550.
    • (2003) Hepatology , vol.37 , pp. 544-550
    • Chalasani, N.1    Gorski, J.C.2    Asghar, M.S.3
  • 28
    • 0035182026 scopus 로고    scopus 로고
    • Repeatability characteristics of simple indices of insulin resistance: Implications for research applications
    • Mather KJ, Hunt AE, Steinberg HO, et al. Repeatability characteristics of simple indices of insulin resistance: implications for research applications. J Clin Endocrinol Metab. 2001;86:5457-5464.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5457-5464
    • Mather, K.J.1    Hunt, A.E.2    Steinberg, H.O.3
  • 29
    • 0036146638 scopus 로고    scopus 로고
    • UDP glucuronosyltransferase mRNA levels in human liver disease
    • Congiu M, Mashford ML, Slavin JL, et al. UDP glucuronosyltransferase mRNA levels in human liver disease. Drug Metab Dispos. 2002;30: 129-134.
    • (2002) Drug Metab Dispos , vol.30 , pp. 129-134
    • Congiu, M.1    Mashford, M.L.2    Slavin, J.L.3
  • 30
    • 0347364706 scopus 로고    scopus 로고
    • Does leptin play a role in the pathogenesis of human nonalcoholic steatohepatitis?
    • Chalasani N, Crabb DW, Cummings OW, et al. Does leptin play a role in the pathogenesis of human nonalcoholic steatohepatitis? Am J Gastroenterol. 2003;98:2771-2776.
    • (2003) Am J Gastroenterol , vol.98 , pp. 2771-2776
    • Chalasani, N.1    Crabb, D.W.2    Cummings, O.W.3
  • 31
    • 4444382031 scopus 로고    scopus 로고
    • Systemic levels of lipid peroxidation and its metabolic and dietary correlates in non-alcoholic steatohepatitis
    • In press
    • Chalasani NDM, Crabb DW. Systemic levels of lipid peroxidation and its metabolic and dietary correlates in non-alcoholic steatohepatitis. Am J Gastroenterol. 2004. In press.
    • (2004) Am J Gastroenterol
    • Chalasani, N.D.M.1    Crabb, D.W.2
  • 32
    • 0842263991 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians
    • Gu HF, Abulaiti A, Ostenson CG, et al. Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians. Diabetes. 2004; 53(suppl 1):31-35.
    • (2004) Diabetes , vol.53 , Issue.1 SUPPL. , pp. 31-35
    • Gu, H.F.1    Abulaiti, A.2    Ostenson, C.G.3
  • 33
    • 18644369745 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians
    • Vasseur F, Helbecque N, Dina C, et al. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. Hum Mol Genet. 2002;11:2607-2614.
    • (2002) Hum Mol Genet , vol.11 , pp. 2607-2614
    • Vasseur, F.1    Helbecque, N.2    Dina, C.3
  • 34
    • 0036091918 scopus 로고    scopus 로고
    • Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: Interaction with family history of type 2 diabetes
    • Stumvoll M, Tschritter O, Fritsche A, et al. Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Diabetes. 2002;51:37-41.
    • (2002) Diabetes , vol.51 , pp. 37-41
    • Stumvoll, M.1    Tschritter, O.2    Fritsche, A.3
  • 35
    • 0036061598 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population
    • Hara K, Boutin P, Mori Y, et al. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes. 2002;51:536-540.
    • (2002) Diabetes , vol.51 , pp. 536-540
    • Hara, K.1    Boutin, P.2    Mori, Y.3
  • 36
    • 0036075053 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations in women with dyslipidemia
    • Matsubara M, Maruoka S, Katayose S. Decreased plasma adiponectin concentrations in women with dyslipidemia. J Clin Endocrinol Metab. 2002;87:2764-2769.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2764-2769
    • Matsubara, M.1    Maruoka, S.2    Katayose, S.3
  • 37
    • 0032489223 scopus 로고    scopus 로고
    • Transdifferentiation of rat hepatic stellate cells results in leptin expression
    • Potter JJ, Womack L, Mezey E, et al. Transdifferentiation of rat hepatic stellate cells results in leptin expression. Biochem Biophys Res Commun. 1998;244:178-182.
    • (1998) Biochem Biophys Res Commun , vol.244 , pp. 178-182
    • Potter, J.J.1    Womack, L.2    Mezey, E.3
  • 38
    • 0036207720 scopus 로고    scopus 로고
    • Apolipoprotein synthesis in nonalcoholic steatohepatitis
    • Charlton M, Sreekumar R, Rasmussen D, et al. Apolipoprotein synthesis in nonalcoholic steatohepatitis. Hepatology. 2002;35:898-904.
    • (2002) Hepatology , vol.35 , pp. 898-904
    • Charlton, M.1    Sreekumar, R.2    Rasmussen, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.