Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia

Laboratory Investigation

Volumn 84, Issue 7, 2004, Pages 884-893

  Lee, Sun ^a   Hwang, Kyu Sang ^b   Lee, Hyeon Joo ^b   Kim, Jung Sun ^c   Kang, Gyeong Hoon ^b,d  

^a National Cancer Center   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c University of Ulsan College of Medicine   (South Korea)

^d Seoul National University Hospital   (South Korea)

Author keywords

Colon adenoma; Colorectal cancer; CpG island; DNA methylation; Tumor suppressor genes

Indexed keywords

APC PROTEIN; CYCLOOXYGENASE 2; DEATH ASSOCIATED PROTEIN KINASE; GLUTATHIONE TRANSFERASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN MLH1; PROTEIN P14; PROTEIN P16; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; THROMBOSPONDIN 1; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UVOMORULIN;

ADULT; AGED; ARTICLE; COLON ADENOMA; COLON CARCINOGENESIS; COLON MUCOSA; COLORECTAL CANCER; CPG ISLAND; FEMALE; GENE INACTIVATION; GENE SILENCING; HUMAN; HUMAN TISSUE; MALE; METHYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADENOMA; ADULT; AGED; AGED, 80 AND OVER; COLON; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION;

EID: 3042693554     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3700108     Document Type: Article

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