Loss of Imprinting of Insulin Growth Factor II Gene: A Potential Heritable Biomarker for Colon Neoplasia Predisposition

Gastroenterology

Volumn 126, Issue 4, 2004, Pages 964-970

  Cruz Correa, Marcia ^a,b,d   Cui, Hengmi ^a   Giardiello, Francis M ^a   Powe, Neil R ^a,c   Hylind, Linda ^a   Robinson, Angela ^a   Hutcheon, David F ^a   Kafonek, David R ^a   Brandenburg, Sheri ^a   Wu, Yiqian ^a   He, Xiaobing ^a   Feinberg, Andrew P ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DEPARTMENT OF COLORECTAL SURGERY   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALCOHOL; BIOLOGICAL MARKER; NONSTEROID ANTIINFLAMMATORY AGENT; SOMATOMEDIN B;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CIGARETTE SMOKING; COLON TUMOR; COLORECTAL TUMOR; DRUG USE; ENVIRONMENTAL FACTOR; FEMALE; GENE; GENOME IMPRINTING; HUMAN; IGF2 GENE; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NUTRIENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK FACTOR; TOBACCO;

EID: 11144356102     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2003.12.051     Document Type: Article

References (39)

1. Feinberg AP. Genomic imprinting in cancer. In: Vogelstein B, Kinzler KW, ed. The genetic basis of human cancer. New York: McGraw-Hill, 1998:95-107.
2. Feinberg A. Imprinting of a genomic domain of 11p15 and loss of imprinting in cancer: an introduction. Cancer Res 1999; 59(suppl):1743-1746.
3. Ravenel JD, Broman KW, Perlman EJ, Niemitz EI, Jayawardena TM, Bell DW, Haber DA, Uejima H, Feinberg AP. Loss of imprinting of insulin-growth factor-II (IGF2) gene in distinguishing specific biologic subtypes of Wilms tumor. J Natl Cancer Inst 2001;93: 1698-1703.
4. Lahm H, Suardet L, Laurent PL, Fischer JR, Ceyhan A, Givel JC, Odartchenko N. Growth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor alpha. Br J Cancer 1992;65:341-346.
5. Gelato MC, Vassalotti J. Insulin-like growth factor-II: possible local growth factor in pheochromocytoma. J Clin Endocrinol Metab 1990;71:1168-1174.
6. El-Badry OM, Minniti C, Kohn EC, Houghton PJ, Daughaday WH, Helman LJ. Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. Cell Growth Differ 1990;1:325-331.
7. Yee D, Cullen KJ, Paik S, Perdue JF, Hampton B, Schwartz A, Lippman ME, Rosen N. Insulin-like growth factor II mRNA expression in human breast cancer. Cancer Res 1988;48:6691-6696.
8. Lamonerie T, Lavialle C, Haddada H, Brison O. IGF-2 autocrine stimulation in tumorigenic clones of a human colon-carcinoma cell line. Int J Cancer 1995;61:587-592.
9. Pommier GJ, Garrouste FL, el Atiq F, Roccabianca M, Marvaldi JL, Remacle-Bonnet MM. Potential autocrine role of insulin-like growth factor II during suramin-induced differentiation of HT29-D4 human colonic adenocarcinoma cell line. Cancer Res 1992;52: 3182-3188.
10. Feinberg AP. A domain of abnormal imprinting in human cancer. Ohlsson R, Hall K, Ritzen M, eds. Nobel Conference on Genomic Imprinting: Causes and Consequences. Cambridge: Cambridge University Press, 1995:273-292.
11. Lee PJ, Washer LL, Law DJ, Boland CR, Horon IL, Feinberg AP. Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation. Proc Natl Acad Sci U S A 1996;93:10366-10370.
12. Lee MP, Hu RJ, Johnson LA, Feinberg AP. Human KvLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements. Nat Genet 1997;15:181-185.
13. Barletta JM, Rainier S, Strichman L, Feinberg AP. Reversal of loss of imprinting in tumor cells by 5-aza-2′-deoxycytidine. Cancer Res 1997;57:48-50.
14. Cui H, Cruz-Correa M, Giardiello F, Hutcheon D, Kafonek D, Brandenburg S, Wu Y, He X, Powe N, Feinberg P. Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science 2003;299:1753-1755.
15. Giovannucci E, Colditz GA, Stampfer MJ, Hunter D, Rosner BA, Willett WC, Speizer FE. A prospective study of cigarette smoking and risk of colorectal adenoma and colorectal cancer in U.S. women. J Natl Cancer Inst 1994;86:192-199.
16. Limburg PJ, Vierkant RA, Cerhan JR, Yang P, Lazovich D, Potter JD, Sellers TA. Cigarette smoking and colorectal cancer: long-term, subsite-specific risks in a cohort study of postmenopausal women. Clin Gastro Hepatol 2003;1:202.
17. Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, Kearney J. A prospective study of cigarette smoking and risk of colorectal adenoma and colorectal cancer in U.S. men. J Natl Cancer Inst 1994;86:183-191.
18. Giovannucci E, Stampfer MJ, Colditz GA, Rimm EB, Trichopoulos D, Rosner BA, Speizer FE, Willett WC. Folate, methionine, and alcohol intake, and the risk of colorectal adenoma. J Natl Cancer Inst 1993;85:875-884.
19. Kono S, Ikeda N, Yanai F, Shinchi K, Imanishi K. Alcoholic beverages and adenomatous polyps of the sigmoid colon: a study of male self-defense officials in Japan. Int J Epidemiol 1990;19: 848-852.
20. Kune GA, Kune S, Read A, MacGowan K, Penfold C, Watson LF. Colorectal polyps, diet, alcohol, and family history of colorectal cancer: a case-control study. Nutr Cancer 1991;16:25-30.
21. Giovannucci E, Egan KM, Hunter DJ, Stampfer MJ, Colditz GA, Willett WC, Speizel FE. Aspirin and the risk of colorectal cancer in women. N Engl J Med 1995;333:609-614.
22. Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, Willett WC. Aspirin use and the risk for colorectal cancer and adenoma in male health professionals. Ann Intern Med 1994; 121:241-246.
23. Sandler RS, Halabi S, Baron JA, Budinger S, Paskett E, Keresztes R, Petrelli N, Pipas JM, Karp DD, Loprinzi CL, Steinbach G, Schilsky R. A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer. N Engl J Med 2003;348:883-890.
24. Baron JA, Cole BF, Sandler RS, Haile RW, Ahnen D, Bresalier R, McKeown-Eyssen G, Summers RW, Rothstein R, Burke CA, Snover DC, Church TR, Allen JI, Beach M, Beck GJ, Bond JH, Byers T, Greenberg ER, Mandel JS, Marcon N, Mott LA, Pearson L, Saibil F, van Stolk RU. A randomized trial of aspirin to prevent colorectal adenomas. N Engl J Med 2003;348:891-899.
25. Baron JA, Beach M, Mandel JS, van Stolk RU, Haile RW, Sandler RS, Rothstein R, Summers RW, Snover DC, Beck GJ, Frankl H, Pearson L, Bond JH, Greenberg ER. Calcium supplements for the prevention of colorectal adenomas. N Engl J Med 1999;340: 101-107.
26. Giovannucci E, Stampfer MJ, Colditz GA, Hunter DJ, Fuchs C, Rosner BA, Speizer FE, Willett WC. Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study. Ann Intern Med 1998;129:517-524.
27. Clark LC, Jacobs ET. Environmental selenium and cancer: risk or protection? Cancer Epidemiol Biomarkers Prev 1998;7:847-848.
28. Benito E, Stiggelbout A, Bosch FX, Obrador A, Kaldor J, Mulet M, Munoz N. Nutritional factors in colorectal cancer risk: a case-control study in Majorca. Int J Cancer 1991;49:161-167.
29. Shike M, Winawer SJ, Greenwald PH. Primary prevention of colorectal cancer. WHO 1990;68:377.
30. Fuchs CS, Giovannucci EL, Colditz GA, Hunter DJ, Stampfer MJ, Rosner B, Speizer FE, Willett WC. Dietary fiber and the risk of colorectal cancer and adenoma in women. N Engl J Med 1999; 340:169-176.
31. Heilbrun LK, Nomura A, Hankin JH, Stemmermann GN. Diet and colorectal cancer with special reference to fiber intake. Int J Cancer 1989;44:1-6.
32. Jain M, Cook GM, Davis FG, Grace MG, Howe GR, Miller AB. A case-control study of diet and colorectal cancer. Int J Cancer 1980;26:757-768.
33. Willett WC, Stampfer MJ, Colditz GA, Rosner BA, Speizer FE. Relation of meat, fat and fiber intake to the risk of colon cancer in a prospective study among women. N Engl J Med 1990;323: 1664-1672.
34. Slattery ML, Schumacher MC, Smith KR, West KR, West DW, Abd-Elghany N. Physical activity, diet, and risk of colon cancer in Utah. Am J Epidemiol 1988;128:989-998.
35. Cui H, Horon IL, Ohlsson R, Hamilton SR, Feinberg AP. Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability. Nat Med 1998;4:1276-1280.
36. Uejima H, Lee MP, Cui H, Feinberg AP. Hot-stop PCR: a simple and general assay for linear quantitation of allele ratios. Nat Genet 2000;25:375-376.
37. Nishihara S, Hayashida T, Mitsuya K, Schultz TC, Ikeguchi M, Kaibara N, Oshimura M. Multipoint imprinting analysis in sporadic colorectal cancers with and without microsatellite instability. Int J Oncol 2000;17:317-322.
38. Nakagawa H, Chadwick RB, Peltomaki P, Plass C, Nakamura Y, de la Chapelle A. Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer. Proc Natl Acad Sci U S A 2001;98:591-596.
39. Cui H, Onyango P, Brandenburg S, Wu Y, Hsieh CL, Feinberg AP. Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. Cancer Res 2002;62:6442-6446.