Expression of the transcriptional repressor Gfi-1 is regulated by C/EBPα and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells

Cancer Research

Volumn 70, Issue 20, 2010, Pages 7949-7959

  Lidonnici, Maria Rosa ^a   Audia, Alessandra ^a   Soliera, Angela Rachele ^a   Prisco, Marco ^a   Ferrari Amorotti, Giovanna ^b   Waldron, Todd ^a   Donato, Nick ^c   Zhang, Ying ^d   Martinez, Robert V ^d   Holyoake, Tessa L ^e   Calabretta, Bruno ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^d PFIZER INC   (United States)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; TRANSCRIPTIONAL REPRESSOR GFI 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHRONIC MYELOID LEUKEMIA; CLONOGENESIS; COLONY FORMATION; DNA BINDING; DNA FLANKING REGION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TRANSFECTION; GRANULOCYTE; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL; LEUKEMOGENESIS; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; RNA INTERFERENCE; WILD TYPE;

CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CCAAT-ENHANCER-BINDING PROTEINS; CELL DIFFERENTIATION; CELL DIVISION; COLONY-FORMING UNITS ASSAY; DNA PRIMERS; DNA-BINDING PROTEINS; DOWN-REGULATION; FUSION PROTEINS, BCR-ABL; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; INVERTED REPEAT SEQUENCES; K562 CELLS; LUCIFERASES; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 78049288554     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-1667     Document Type: Article

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