메뉴 건너뛰기




Volumn 13, Issue 4, 2008, Pages 299-310

Modeling of C/EBPα Mutant Acute Myeloid Leukemia Reveals a Common Expression Signature of Committed Myeloid Leukemia-Initiating Cells

Author keywords

CELLCYCLE

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; MIXED LINEAGE LEUKEMIA PROTEIN; PROTEIN P30; PROTEIN P42; CD11B ANTIGEN; ISOPROTEIN; MUTANT PROTEIN; STEM CELL FACTOR RECEPTOR;

EID: 41249103144     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2008.02.008     Document Type: Article
Times cited : (208)

References (36)
  • 1
    • 0041370095 scopus 로고    scopus 로고
    • Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
    • Ayton P.M., and Cleary M.L. Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9. Genes Dev. 17 (2003) 2298-2307
    • (2003) Genes Dev. , vol.17 , pp. 2298-2307
    • Ayton, P.M.1    Cleary, M.L.2
  • 2
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D., and Dick J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3 (1997) 730-737
    • (1997) Nat. Med. , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 3
    • 0346100567 scopus 로고    scopus 로고
    • Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
    • Cozzio A., Passegue E., Ayton P.M., Karsunky H., Cleary M.L., and Weissman I.L. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev. 17 (2003) 3029-3035
    • (2003) Genes Dev. , vol.17 , pp. 3029-3035
    • Cozzio, A.1    Passegue, E.2    Ayton, P.M.3    Karsunky, H.4    Cleary, M.L.5    Weissman, I.L.6
  • 4
    • 1442356729 scopus 로고    scopus 로고
    • CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: prognostic relevance and analysis of cooperating mutations
    • Frohling S., Schlenk R.F., Stolze I., Bihlmayr J., Benner A., Kreitmeier S., Tobis K., Dohner H., and Dohner K. CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: prognostic relevance and analysis of cooperating mutations. J. Clin. Oncol. 22 (2004) 624-633
    • (2004) J. Clin. Oncol. , vol.22 , pp. 624-633
    • Frohling, S.1    Schlenk, R.F.2    Stolze, I.3    Bihlmayr, J.4    Benner, A.5    Kreitmeier, S.6    Tobis, K.7    Dohner, H.8    Dohner, K.9
  • 5
    • 4444233646 scopus 로고    scopus 로고
    • C/EBPα deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo
    • Heath V., Suh H.C., Holman M., Renn K., Gooya J.M., Parkin S., Klarmann K.D., Ortiz M., Johnson P., and Keller J. C/EBPα deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo. Blood 104 (2004) 1639-1647
    • (2004) Blood , vol.104 , pp. 1639-1647
    • Heath, V.1    Suh, H.C.2    Holman, M.3    Renn, K.4    Gooya, J.M.5    Parkin, S.6    Klarmann, K.D.7    Ortiz, M.8    Johnson, P.9    Keller, J.10
  • 8
    • 33748850636 scopus 로고    scopus 로고
    • Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
    • Kirstetter P., Anderson K., Porse B.T., Jacobsen S.E., and Nerlov C. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat. Immunol. 7 (2006) 1048-1056
    • (2006) Nat. Immunol. , vol.7 , pp. 1048-1056
    • Kirstetter, P.1    Anderson, K.2    Porse, B.T.3    Jacobsen, S.E.4    Nerlov, C.5
  • 9
    • 0030582532 scopus 로고    scopus 로고
    • Characterization of two ELISAs for NGAL, a newly described lipocalin in human neutrophils
    • Kjeldsen L., Koch C., Arnljots K., and Borregaard N. Characterization of two ELISAs for NGAL, a newly described lipocalin in human neutrophils. J. Immunol. Methods 198 (1996) 155-164
    • (1996) J. Immunol. Methods , vol.198 , pp. 155-164
    • Kjeldsen, L.1    Koch, C.2    Arnljots, K.3    Borregaard, N.4
  • 10
    • 0036785393 scopus 로고    scopus 로고
    • Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors
    • Kottaridis P.D., Gale R.E., Langabeer S.E., Frew M.E., Bowen D.T., and Linch D.C. Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors. Blood 100 (2002) 2393-2398
    • (2002) Blood , vol.100 , pp. 2393-2398
    • Kottaridis, P.D.1    Gale, R.E.2    Langabeer, S.E.3    Frew, M.E.4    Bowen, D.T.5    Linch, D.C.6
  • 14
    • 0027420920 scopus 로고
    • A 30-kDa alternative translation product of the CCAAT/enhancer binding protein α message: transcriptional activator lacking antimitotic activity
    • Lin F.T., MacDougald O.A., Diehl A.M., and Lane M.D. A 30-kDa alternative translation product of the CCAAT/enhancer binding protein α message: transcriptional activator lacking antimitotic activity. Proc. Natl. Acad. Sci. USA 90 (1993) 9606-9610
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9606-9610
    • Lin, F.T.1    MacDougald, O.A.2    Diehl, A.M.3    Lane, M.D.4
  • 15
    • 20044388101 scopus 로고    scopus 로고
    • Characterization of CEBPA mutations in acute myeloid leukemia: most patients with CEBPA mutations have biallelic mutations and show a distinct immunophenotype of the leukemic cells
    • Lin L.I., Chen C.Y., Lin D.T., Tsay W., Tang J.L., Yeh Y.C., Shen H.L., Su F.H., Yao M., Huang S.Y., et al. Characterization of CEBPA mutations in acute myeloid leukemia: most patients with CEBPA mutations have biallelic mutations and show a distinct immunophenotype of the leukemic cells. Clin. Cancer Res. 11 (2005) 1372-1379
    • (2005) Clin. Cancer Res. , vol.11 , pp. 1372-1379
    • Lin, L.I.1    Chen, C.Y.2    Lin, D.T.3    Tsay, W.4    Tang, J.L.5    Yeh, Y.C.6    Shen, H.L.7    Su, F.H.8    Yao, M.9    Huang, S.Y.10
  • 17
    • 2342544921 scopus 로고    scopus 로고
    • C/EBPα mutations in acute myeloid leukaemias
    • Nerlov C. C/EBPα mutations in acute myeloid leukaemias. Nat. Rev. Cancer 4 (2004) 394-400
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 394-400
    • Nerlov, C.1
  • 23
    • 21744438305 scopus 로고    scopus 로고
    • Further evidence that germline CEBPA mutations cause dominant inheritance of acute myeloid leukaemia
    • Sellick G.S., Spendlove H.E., Catovsky D., Pritchard-Jones K., and Houlston R.S. Further evidence that germline CEBPA mutations cause dominant inheritance of acute myeloid leukaemia. Leukemia 19 (2005) 1276-1278
    • (2005) Leukemia , vol.19 , pp. 1276-1278
    • Sellick, G.S.1    Spendlove, H.E.2    Catovsky, D.3    Pritchard-Jones, K.4    Houlston, R.S.5
  • 24
    • 0036786289 scopus 로고    scopus 로고
    • Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse
    • Shih L.Y., Huang C.F., Wu J.H., Lin T.L., Dunn P., Wang P.N., Kuo M.C., Lai C.L., and Hsu H.C. Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse. Blood 100 (2002) 2387-2392
    • (2002) Blood , vol.100 , pp. 2387-2392
    • Shih, L.Y.1    Huang, C.F.2    Wu, J.H.3    Lin, T.L.4    Dunn, P.5    Wang, P.N.6    Kuo, M.C.7    Lai, C.L.8    Hsu, H.C.9
  • 25
    • 33646474281 scopus 로고    scopus 로고
    • AML patients with CEBPα mutations mostly retain identical mutant patterns but frequently change in allelic distribution at relapse: a comparative analysis on paired diagnosis and relapse samples
    • Shih L.Y., Liang D.C., Huang C.F., Wu J.H., Lin T.L., Wang P.N., Dunn P., Kuo M.C., and Tang T.C. AML patients with CEBPα mutations mostly retain identical mutant patterns but frequently change in allelic distribution at relapse: a comparative analysis on paired diagnosis and relapse samples. Leukemia 20 (2006) 604-609
    • (2006) Leukemia , vol.20 , pp. 604-609
    • Shih, L.Y.1    Liang, D.C.2    Huang, C.F.3    Wu, J.H.4    Lin, T.L.5    Wang, P.N.6    Dunn, P.7    Kuo, M.C.8    Tang, T.C.9
  • 27
    • 33749440584 scopus 로고    scopus 로고
    • Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia
    • Somervaille T.C., and Cleary M.L. Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia. Cancer Cell 10 (2006) 257-268
    • (2006) Cancer Cell , vol.10 , pp. 257-268
    • Somervaille, T.C.1    Cleary, M.L.2
  • 34
    • 35948964020 scopus 로고    scopus 로고
    • Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential
    • Wong P., Iwasaki M., Somervaille T.C., So C.W., and Cleary M.L. Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential. Genes Dev. 21 (2007) 2762-2774
    • (2007) Genes Dev. , vol.21 , pp. 2762-2774
    • Wong, P.1    Iwasaki, M.2    Somervaille, T.C.3    So, C.W.4    Cleary, M.L.5
  • 35
    • 0031029557 scopus 로고    scopus 로고
    • Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice
    • Zhang D.E., Zhang P., Wang N.D., Hetherington C.J., Darlington G.J., and Tenen D.G. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice. Proc. Natl. Acad. Sci. USA 94 (1997) 569-574
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 569-574
    • Zhang, D.E.1    Zhang, P.2    Wang, N.D.3    Hetherington, C.J.4    Darlington, G.J.5    Tenen, D.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.