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Volumn 10, Issue 7, 2010, Pages 653-666

Hypoxia and fetal heart development

Author keywords

Development; Fetal heart; Fetal programming; Hypoxia

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEAT SHOCK PROTEIN 70; HYPOXIA INDUCIBLE FACTOR 1; PROTEIN KINASE C EPSILON; VASCULOTROPIN;

EID: 77957973733     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652410792630643     Document Type: Article
Times cited : (183)

References (166)
  • 2
    • 0029012868 scopus 로고
    • Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids
    • Gross MW, Karbach U, Groebe K, Franko AJ, Mueller-Klieser W. Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids. Int J Cancer 1995; 61: 567-73.
    • (1995) Int J Cancer , vol.61 , pp. 567-573
    • Gross, M.W.1    Karbach, U.2    Groebe, K.3    Franko, A.J.4    Mueller-Klieser, W.5
  • 3
    • 0032170012 scopus 로고    scopus 로고
    • Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker
    • Raleigh JA, Calkin-Adams DP, Rinker LH, et al. Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker. Cancer Res 1998; 58: 3765-8.
    • (1998) Cancer Res , vol.58 , pp. 3765-3768
    • Raleigh, J.A.1    Calkin-Adams, D.P.2    Rinker, L.H.3
  • 4
    • 70349212272 scopus 로고    scopus 로고
    • Plasticity of the muscle proteome to exercise at altitude
    • Flueck M. Plasticity of the muscle proteome to exercise at altitude. High Alt Med Biol 2009; 10: 183-93.
    • (2009) High Alt Med Biol , vol.10 , pp. 183-193
    • Flueck, M.1
  • 5
    • 62149108987 scopus 로고    scopus 로고
    • Hypoxia or in situ normoxia: The stem cell paradigm
    • Ivanovic Z. Hypoxia or in situ normoxia: The stem cell paradigm. J Cell Physiol 2009; 219: 271-5.
    • (2009) J Cell Physiol , vol.219 , pp. 271-275
    • Ivanovic, Z.1
  • 6
    • 34547899979 scopus 로고    scopus 로고
    • Role of hypoxia in the evolution and development of the cardiovascular system
    • Fisher SA, Burggren WW. Role of hypoxia in the evolution and development of the cardiovascular system. Antioxid Redox Signal 2007; 9: 1339-52.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 1339-1352
    • Fisher, S.A.1    Burggren, W.W.2
  • 7
    • 37349006946 scopus 로고    scopus 로고
    • Prenatal nicotine exposure increases heart susceptibility to ischemia/reperfusion injury in adult offspring
    • Lawrence J, Xiao D, Xue Q, Rejali M, Yang S, Zhang L. Prenatal nicotine exposure increases heart susceptibility to ischemia/reperfusion injury in adult offspring. J Pharmacol Exp Ther 2008; 324: 331-41.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 331-341
    • Lawrence, J.1    Xiao, D.2    Xue, Q.3    Rejali, M.4    Yang, S.5    Zhang, L.6
  • 8
    • 0029869829 scopus 로고    scopus 로고
    • Ethanol increases uterine blood flow and fetal arterial blood oxygen tension in the near-term pregnant ewe
    • Reynolds JD, Penning DH, Dexter F, et al. Ethanol increases uterine blood flow and fetal arterial blood oxygen tension in the near-term pregnant ewe. Alcohol 1996; 13: 251-6.
    • (1996) Alcohol , vol.13 , pp. 251-256
    • Reynolds, J.D.1    Penning, D.H.2    Dexter, F.3
  • 9
    • 0026538047 scopus 로고
    • Effects of alcohol on intrauterine oxygen tension in the rat
    • Mitchell JA, Van Kainen BR. Effects of alcohol on intrauterine oxygen tension in the rat. Alcohol Clin Exp Res 1992; 16: 308-10.
    • (1992) Alcohol Clin Exp Res , vol.16 , pp. 308-310
    • Mitchell, J.A.1    van Kainen, B.R.2
  • 10
  • 11
    • 33645306841 scopus 로고    scopus 로고
    • Placental adaptive responses and fetal programming
    • Myatt L. Placental adaptive responses and fetal programming. J Physiol 2006; 572: 25-30.
    • (2006) J Physiol , vol.572 , pp. 25-30
    • Myatt, L.1
  • 12
    • 0030433627 scopus 로고    scopus 로고
    • Substrate metabolism in the developing heart
    • Ascuitto RJ, Ross-Ascuitto NT. Substrate metabolism in the developing heart. Semin Perinatol 1996; 20: 542-63.
    • (1996) Semin Perinatol , vol.20 , pp. 542-563
    • Ascuitto, R.J.1    Ross-Ascuitto, N.T.2
  • 13
    • 0345490692 scopus 로고    scopus 로고
    • Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha
    • Compernolle V, Brusselmans K, Franco D, et al. Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha. Cardiovasc Res 2003; 60: 569-79.
    • (2003) Cardiovasc Res , vol.60 , pp. 569-579
    • Compernolle, V.1    Brusselmans, K.2    Franco, D.3
  • 14
    • 4344655389 scopus 로고    scopus 로고
    • Hypoxia-responsive signaling regulates the apoptosis-dependent remodeling of the embryonic avian cardiac outflow tract
    • Sugishita Y, Leifer DW, Agani F, Watanabe M, Fisher SA. Hypoxia-responsive signaling regulates the apoptosis-dependent remodeling of the embryonic avian cardiac outflow tract. Dev Biol 2004; 273: 285-96.
    • (2004) Dev Biol , vol.273 , pp. 285-296
    • Sugishita, Y.1    Leifer, D.W.2    Agani, F.3    Watanabe, M.4    Fisher, S.A.5
  • 16
    • 0030806299 scopus 로고    scopus 로고
    • Fashioning the vertebrate heart: Earliest embryonic decisions
    • Fishman MC, Chien KR. Fashioning the vertebrate heart: earliest embryonic decisions. Development 1997; 124: 2099-117.
    • (1997) Development , vol.124 , pp. 2099-2117
    • Fishman, M.C.1    Chien, K.R.2
  • 17
    • 33644968171 scopus 로고    scopus 로고
    • Differential levels of tissue hypoxia in the developing chicken heart
    • Wikenheiser J, Doughman YQ, Fisher SA, Watanabe M. Differential levels of tissue hypoxia in the developing chicken heart. Dev Dyn 2006; 235: 115-23.
    • (2006) Dev Dyn , vol.235 , pp. 115-123
    • Wikenheiser, J.1    Doughman, Y.Q.2    Fisher, S.A.3    Watanabe, M.4
  • 18
    • 33644887993 scopus 로고    scopus 로고
    • Experimental hypoxia and embryonic angiogenesis
    • Nanka O, Valasek P, Dvorakova M, Grim M. Experimental hypoxia and embryonic angiogenesis. Dev Dyn 2006; 235: 723-33.
    • (2006) Dev Dyn , vol.235 , pp. 723-733
    • Nanka, O.1    Valasek, P.2    Dvorakova, M.3    Grim, M.4
  • 19
    • 0020388920 scopus 로고
    • Participation of the sarcolemma in the control of relaxation of the mammalian heart during perinatal development
    • Hoerter JA, Vassort G. Participation of the sarcolemma in the control of relaxation of the mammalian heart during perinatal development. Adv Myocardiol 1982; 3: 373-80.
    • (1982) Adv Myocardiol , vol.3 , pp. 373-380
    • Hoerter, J.A.1    Vassort, G.2
  • 20
    • 33847698562 scopus 로고    scopus 로고
    • Myocyte enlargement, differentiation, and proliferation kinetics in the fetal sheep heart
    • Jonker SS, Zhang L, Louey S, Giraud GD, Thornburg KL, Faber JJ. Myocyte enlargement, differentiation, and proliferation kinetics in the fetal sheep heart. J Appl Physiol 2007; 102: 1130-42.
    • (2007) J Appl Physiol , vol.102 , pp. 1130-1142
    • Jonker, S.S.1    Zhang, L.2    Louey, S.3    Giraud, G.D.4    Thornburg, K.L.5    Faber, J.J.6
  • 21
    • 0034040444 scopus 로고    scopus 로고
    • Myocardial growth before and after birth: Clinical implications
    • Rudolph AM. Myocardial growth before and after birth: clinical implications. Acta Paediatr 2000; 89: 129-33.
    • (2000) Acta Paediatr , vol.89 , pp. 129-133
    • Rudolph, A.M.1
  • 22
    • 0015993323 scopus 로고
    • Response of the adult newt ventricle to injury
    • Oberpriller JO, Oberpriller JC. Response of the adult newt ventricle to injury. J Exp Zool 1974; 187: 249-53.
    • (1974) J Exp Zool , vol.187 , pp. 249-253
    • Oberpriller, J.O.1    Oberpriller, J.C.2
  • 23
    • 0037073890 scopus 로고    scopus 로고
    • Heart regeneration in zebrafish
    • Poss KD, Wilson LG, Keating MT. Heart regeneration in zebrafish. Science 2002; 298: 2188-90.
    • (2002) Science , vol.298 , pp. 2188-2190
    • Poss, K.D.1    Wilson, L.G.2    Keating, M.T.3
  • 24
    • 0142074727 scopus 로고    scopus 로고
    • Heterogeneous proliferative potential in regenerative adult newt cardiomyocytes
    • Bettencourt-Dias M, Mittnacht S, Brockes JP. Heterogeneous proliferative potential in regenerative adult newt cardiomyocytes. J Cell Sci 2003; 116: 4001-9
    • (2003) J Cell Sci , vol.116 , pp. 4001-4009
    • Bettencourt-Dias, M.1    Mittnacht, S.2    Brockes, J.P.3
  • 25
    • 18844383961 scopus 로고    scopus 로고
    • P38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes
    • Engel FB, Schebesta M, Duong MT, et al. p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. Genes Dev 2005; 19: 1175-87.
    • (2005) Genes Dev , vol.19 , pp. 1175-1187
    • Engel, F.B.1    Schebesta, M.2    Duong, M.T.3
  • 26
    • 0033712740 scopus 로고    scopus 로고
    • Right ventricular systolic pressure load alters myocyte maturation in fetal sheep
    • Barbera A, Giraud GD, Reller MD, et al. Right ventricular systolic pressure load alters myocyte maturation in fetal sheep. Am J Physiol Regul Integr Comp Physiol 2000; 279: R1157-64.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.279
    • Barbera, A.1    Giraud, G.D.2    Reller, M.D.3
  • 28
    • 0028284643 scopus 로고
    • Cardiac function in fetal sheep during two weeks of hypoxemia
    • Kamitomo M, Longo LD, Gilbert RD: Cardiac function in fetal sheep during two weeks of hypoxemia. Am J Physiol 1994; 266: R1778-85.
    • (1994) Am J Physiol , vol.266
    • Kamitomo, M.1    Longo, L.D.2    Gilbert, R.D.3
  • 29
    • 0014241738 scopus 로고
    • Developmental changes of myocardial metabolism. II. Myocardial metabolism of fatty acids in the early postnatal period in dogs
    • Breuer E, Barta E, Zlatos L, Pappova E. Developmental changes of myocardial metabolism. II. Myocardial metabolism of fatty acids in the early postnatal period in dogs. Biol Neonat 1968; 12: 54-64.
    • (1968) Biol Neonat , vol.12 , pp. 54-64
    • Breuer, E.1    Barta, E.2    Zlatos, L.3    Pappova, E.4
  • 30
    • 0018635742 scopus 로고
    • Hypoxic sensitizers-implications for radiation therapy
    • Chapman JD. Hypoxic sensitizers-implications for radiation therapy. N Engl J Med 1979; 301: 1429-32.
    • (1979) N Engl J Med , vol.301 , pp. 1429-1432
    • Chapman, J.D.1
  • 31
    • 35448972596 scopus 로고    scopus 로고
    • Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome
    • Evans SM, Du KL, Chalian AA, et al. Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome. Int J Radiat Oncol Biol Phys 2007; 69: 1024-31.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 1024-1031
    • Evans, S.M.1    Du, K.L.2    Chalian, A.A.3
  • 32
    • 57149119496 scopus 로고    scopus 로고
    • Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors
    • Evans SM, Jenkins KW, Jenkins WT, et al. Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors. Radiat Res 2008; 170: 677-90.
    • (2008) Radiat Res , vol.170 , pp. 677-690
    • Evans, S.M.1    Jenkins, K.W.2    Jenkins, W.T.3
  • 33
    • 0037223816 scopus 로고    scopus 로고
    • Non-invasive PET and SPECT imaging of tissue hypoxia using isotopically labeled 2-nitroimidazoles
    • Koch CJ, Evans SM. Non-invasive PET and SPECT imaging of tissue hypoxia using isotopically labeled 2-nitroimidazoles. Adv Exp Med Biol 2003; 510: 285-92.
    • (2003) Adv Exp Med Biol , vol.510 , pp. 285-292
    • Koch, C.J.1    Evans, S.M.2
  • 34
    • 15444342958 scopus 로고    scopus 로고
    • Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
    • Iyer NV, Kotch LE, Agani F, et al. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 1998; 12: 149-62.
    • (1998) Genes Dev , vol.12 , pp. 149-162
    • Iyer, N.V.1    Kotch, L.E.2    Agani, F.3
  • 35
    • 0032190614 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Master regulator of O2 homeostasis
    • Semenza GL. Hypoxia-inducible factor 1: master regulator of O2 homeostasis. Curr Opin Genet Dev 1998; 8: 588-94.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 588-594
    • Semenza, G.L.1
  • 36
    • 37549071449 scopus 로고    scopus 로고
    • Oxygen sensors in context
    • Ward J. Oxygen sensors in context. Biochim Biophys Acta 2008; 1777: 1-14.
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 1-14
    • Ward, J.1
  • 37
    • 0029944965 scopus 로고    scopus 로고
    • Dimerization, DNA binding binding, and transactivation properties of hypoxia-inducible factor 1
    • Jiang BH, Rue E, Wang GL, Roe R, Semenza GL. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J Biol Chem 1996; 271: 17771-8.
    • (1996) J Biol Chem , vol.271 , pp. 17771-17778
    • Jiang, B.H.1    Rue, E.2    Wang, G.L.3    Roe, R.4    Semenza, G.L.5
  • 38
    • 40449087690 scopus 로고    scopus 로고
    • The non-haematopoietic biological effects of erythropoietin
    • Arcasoy MO. The non-haematopoietic biological effects of erythropoietin. Br J Haematol 2008; 141: 14-31.
    • (2008) Br J Haematol , vol.141 , pp. 14-31
    • Arcasoy, M.O.1
  • 39
    • 56349124221 scopus 로고    scopus 로고
    • Erythropoietin in heart and vessels: Focus on transcription and signalling pathways
    • Marzo F, Lavorgna A, Coluzzi G, et al. Erythropoietin in heart and vessels: focus on transcription and signalling pathways. J Thromb Thrombolysis 2008; 26: 183-7.
    • (2008) J Thromb Thrombolysis , vol.26 , pp. 183-187
    • Marzo, F.1    Lavorgna, A.2    Coluzzi, G.3
  • 40
    • 0035584217 scopus 로고    scopus 로고
    • Apoptosis is required for the proper formation of the ventriculo-arterial connections
    • Watanabe M, Jafri A, Fisher SA. Apoptosis is required for the proper formation of the ventriculo-arterial connections. Dev Biol 2001; 240: 274-88.
    • (2001) Dev Biol , vol.240 , pp. 274-288
    • Watanabe, M.1    Jafri, A.2    Fisher, S.A.3
  • 41
    • 33748316795 scopus 로고    scopus 로고
    • Apoptosis in the developing mouse heart
    • Barbosky L, Lawrence DK, Karunamuni G, et al. Apoptosis in the developing mouse heart. Dev Dyn 2006; 235: 2592-602.
    • (2006) Dev Dyn , vol.235 , pp. 2592-2602
    • Barbosky, L.1    Lawrence, D.K.2    Karunamuni, G.3
  • 42
    • 36049035683 scopus 로고    scopus 로고
    • The expression patterns of hypoxia-inducing factor subunit alpha-1, heme oxygenase, hypoxia upregulated protein 1, and cardiac troponin T during development of the chicken heart
    • Druyan S, Cahaner A, Ashwell CM. The expression patterns of hypoxia-inducing factor subunit alpha-1, heme oxygenase, hypoxia upregulated protein 1, and cardiac troponin T during development of the chicken heart. Poult Sci 2007; 86: 2384-9.
    • (2007) Poult Sci , vol.86 , pp. 2384-2389
    • Druyan, S.1    Cahaner, A.2    Ashwell, C.M.3
  • 43
    • 0032496159 scopus 로고    scopus 로고
    • Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes
    • Duranteau J, Chandel NS, Kulisz A, et al. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J Biol Chem 1998; 273: 11619-24.
    • (1998) J Biol Chem , vol.273 , pp. 11619-11624
    • Duranteau, J.1    Chandel, N.S.2    Kulisz, A.3
  • 44
    • 0035142809 scopus 로고    scopus 로고
    • Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: A possible signal for vessel development
    • Lee YM, Jeong CH, Koo SY, et al. Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development. Dev Dyn 2001; 220: 175-86.
    • (2001) Dev Dyn , vol.220 , pp. 175-186
    • Lee, Y.M.1    Jeong, C.H.2    Koo, S.Y.3
  • 45
    • 1542297346 scopus 로고    scopus 로고
    • Role of myocardial hypoxia in the remodeling of the embryonic avian cardiac outflow tract
    • Sugishita Y, Watanabe M, Fisher SA. Role of myocardial hypoxia in the remodeling of the embryonic avian cardiac outflow tract. Dev Biol 2004; 267: 294-308.
    • (2004) Dev Biol , vol.267 , pp. 294-308
    • Sugishita, Y.1    Watanabe, M.2    Fisher, S.A.3
  • 46
    • 0026782588 scopus 로고
    • Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy
    • Rodesch F, Simon P, Donner C, Jauniaux E. Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstet Gynecol 1992; 80: 283-5.
    • (1992) Obstet Gynecol , vol.80 , pp. 283-285
    • Rodesch, F.1    Simon, P.2    Donner, C.3    Jauniaux, E.4
  • 47
    • 0035062024 scopus 로고    scopus 로고
    • Evaluation of respiratory gases and acid-base gradients in human fetal fluids and uteroplacental tissue between 7 and 16 weeks' gestation
    • Jauniaux E, Watson A, Burton G. Evaluation of respiratory gases and acid-base gradients in human fetal fluids and uteroplacental tissue between 7 and 16 weeks' gestation. Am J Obstet Gynecol 2001; 184: 998-1003.
    • (2001) Am J Obstet Gynecol , vol.184 , pp. 998-1003
    • Jauniaux, E.1    Watson, A.2    Burton, G.3
  • 48
    • 0023027644 scopus 로고
    • Effect of gestational age on fetal and intervillous blood gas and acid-base values in human pregnancy
    • Soothill PW, Nicolaides KH, Rodeck CH, Campbell S. Effect of gestational age on fetal and intervillous blood gas and acid-base values in human pregnancy. Fetal Ther 1986; 1: 168-75.
    • (1986) Fetal Ther , vol.1 , pp. 168-175
    • Soothill, P.W.1    Nicolaides, K.H.2    Rodeck, C.H.3    Campbell, S.4
  • 50
    • 33646228404 scopus 로고    scopus 로고
    • Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish
    • Covassin LD, Villefranc JA, Kacergis MC, Weinstein BM, Lawson ND. Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish. Proc Natl Acad Sci USA 2006; 103: 6554-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6554-6559
    • Covassin, L.D.1    Villefranc, J.A.2    Kacergis, M.C.3    Weinstein, B.M.4    Lawson, N.D.5
  • 51
    • 33749208496 scopus 로고    scopus 로고
    • Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant
    • Nasevicius A, Larson J, Ekker SC. Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast 2000; 17: 294-301.
    • (2000) Yeast , vol.17 , pp. 294-301
    • Nasevicius, A.1    Larson, J.2    Ekker, S.C.3
  • 52
    • 4143055723 scopus 로고    scopus 로고
    • Zebrafish neuropilins are differentially expressed and interact with vascular endothelial growth factor during embryonic vascular development
    • Martyn U, Schulte-Merker S. Zebrafish neuropilins are differentially expressed and interact with vascular endothelial growth factor during embryonic vascular development. Dev Dyn 2004; 231: 33-42.
    • (2004) Dev Dyn , vol.231 , pp. 33-42
    • Martyn, U.1    Schulte-Merker, S.2
  • 54
    • 0036088478 scopus 로고    scopus 로고
    • Mechanisms of normal and tumor-derived angiogenesis
    • Papetti M, Herman IM. Mechanisms of normal and tumor-derived angiogenesis. Am J Physiol Cell Physiol 2002; 282: C947-70.
    • (2002) Am J Physiol Cell Physiol , vol.282
    • Papetti, M.1    Herman, I.M.2
  • 55
    • 0033772970 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its effect on angiogenesis
    • Josko J, Gwozdz B, Jedrzejowska-Szypulka H, Hendryk S. Vascular endothelial growth factor (VEGF) and its effect on angiogenesis. Med Sci Monit 2000; 6: 1047-52.
    • (2000) Med Sci Monit , vol.6 , pp. 1047-1052
    • Josko, J.1    Gwozdz, B.2    Jedrzejowska-Szypulka, H.3    Hendryk, S.4
  • 56
    • 50849120002 scopus 로고    scopus 로고
    • VEGF receptor protein-tyrosine kinases: Structure and regulation
    • Roskoski R, Jr. VEGF receptor protein-tyrosine kinases: structure and regulation. Biochem Biophys Res Commun 2008; 375: 287-91.
    • (2008) Biochem Biophys Res Commun , vol.375 , pp. 287-291
    • Roskoski Jr., R.1
  • 57
    • 33847421319 scopus 로고    scopus 로고
    • Vascular endothelial growth factors: Biology and current status of clinical applications in cardiovascular medicine
    • Yla-Herttuala S, Rissanen TT, Vajanto I, Hartikainen J. Vascular endothelial growth factors: biology and current status of clinical applications in cardiovascular medicine. J Am Coll Cardiol 2007; 49: 1015-26.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1015-1026
    • Yla-Herttuala, S.1    Rissanen, T.T.2    Vajanto, I.3    Hartikainen, J.4
  • 58
  • 59
    • 0032964554 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression coincides with coronary vasculogenesis and angiogenesis
    • Tomanek RJ, Ratajska A, Kitten GT, Yue X, Sandra A. Vascular endothelial growth factor expression coincides with coronary vasculogenesis and angiogenesis. Dev Dyn 1999; 215: 54-61.
    • (1999) Dev Dyn , vol.215 , pp. 54-61
    • Tomanek, R.J.1    Ratajska, A.2    Kitten, G.T.3    Yue, X.4    Sandra, A.5
  • 60
    • 0842270034 scopus 로고    scopus 로고
    • Hypoxic induction of myocardial vascularization during development
    • Tomanek RJ, Lund DD, Yue X. Hypoxic induction of myocardial vascularization during development. Adv Exp Med Biol 2003; 543: 139-49.
    • (2003) Adv Exp Med Biol , vol.543 , pp. 139-149
    • Tomanek, R.J.1    Lund, D.D.2    Yue, X.3
  • 61
    • 14344279280 scopus 로고    scopus 로고
    • A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function
    • Giordano FJ, Gerber HP, Williams SP, et al. A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function. Proc Natl Acad Sci USA 2001; 98: 5780-5.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5780-5785
    • Giordano, F.J.1    Gerber, H.P.2    Williams, S.P.3
  • 62
    • 6744265274 scopus 로고    scopus 로고
    • Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation
    • Takeuchi S, Takeda K, Oishi I, et al. Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation. Genes Cells 2000; 5: 71-8.
    • (2000) Genes Cells , vol.5 , pp. 71-78
    • Takeuchi, S.1    Takeda, K.2    Oishi, I.3
  • 63
    • 0032833413 scopus 로고    scopus 로고
    • Stimulation of coronary vasculogenesis/angiogenesis by hypoxia in cultured embryonic hearts
    • Yue X, Tomanek RJ. Stimulation of coronary vasculogenesis/angiogenesis by hypoxia in cultured embryonic hearts. Dev Dyn 1999; 216: 28-36.
    • (1999) Dev Dyn , vol.216 , pp. 28-36
    • Yue, X.1    Tomanek, R.J.2
  • 64
    • 48849094266 scopus 로고    scopus 로고
    • Targeting angiogenesis in renal cell carcinoma
    • Lainakis G, Bamias A. Targeting angiogenesis in renal cell carcinoma. Curr Cancer Drug Targets 2008; 8: 349-58.
    • (2008) Curr Cancer Drug Targets , vol.8 , pp. 349-358
    • Lainakis, G.1    Bamias, A.2
  • 65
    • 0345491599 scopus 로고    scopus 로고
    • Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
    • Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC. Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol Cell Biol 2003; 23: 9361-74.
    • (2003) Mol Cell Biol , vol.23 , pp. 9361-9374
    • Hu, C.J.1    Wang, L.Y.2    Chodosh, L.A.3    Keith, B.4    Simon, M.C.5
  • 66
    • 0029761644 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
    • Forsythe JA, Jiang BH, Iyer NV, et al. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 1996; 16: 4604-13.
    • (1996) Mol Cell Biol , vol.16 , pp. 4604-4613
    • Forsythe, J.A.1    Jiang, B.H.2    Iyer, N.V.3
  • 67
    • 0033562569 scopus 로고    scopus 로고
    • Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death
    • Kotch LE, Iyer NV, Laughner E, Semenza GL. Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death. Dev Biol 1999; 209: 254-67.
    • (1999) Dev Biol , vol.209 , pp. 254-267
    • Kotch, L.E.1    Iyer, N.V.2    Laughner, E.3    Semenza, G.L.4
  • 68
    • 0032529104 scopus 로고    scopus 로고
    • PDGF mediates cardiac microvascular communication
    • Edelberg JM, Aird WC, Wu W, et al. PDGF mediates cardiac microvascular communication. J Clin Invest 1998; 102: 837-43.
    • (1998) J Clin Invest , vol.102 , pp. 837-843
    • Edelberg, J.M.1    Aird, W.C.2    Wu, W.3
  • 69
    • 44949256424 scopus 로고    scopus 로고
    • Hypoxia-inducible transcription factor-1alpha triggers an autocrine survival pathway during embryonic cardiac outflow tract remodeling
    • Liu H, Fisher SA. Hypoxia-inducible transcription factor-1alpha triggers an autocrine survival pathway during embryonic cardiac outflow tract remodeling. Circ Res 2008; 102: 1331-9.
    • (2008) Circ Res , vol.102 , pp. 1331-1339
    • Liu, H.1    Fisher, S.A.2
  • 70
    • 0032781007 scopus 로고    scopus 로고
    • Regulation of cardiovascular development and physiology by hypoxia-inducible factor 1
    • Semenza GL, Agani F, Iyer N, et al. Regulation of cardiovascular development and physiology by hypoxia-inducible factor 1. Ann N Y Acad Sci 1999; 874: 262-8.
    • (1999) Ann N Y Acad Sci , vol.874 , pp. 262-268
    • Semenza, G.L.1    Agani, F.2    Iyer, N.3
  • 72
    • 0034671706 scopus 로고    scopus 로고
    • Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses
    • Adelman DM, Gertsenstein M, Nagy A, Simon MC, Maltepe E. Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses. Genes Dev 2000; 14: 3191-203.
    • (2000) Genes Dev , vol.14 , pp. 3191-3203
    • Adelman, D.M.1    Gertsenstein, M.2    Nagy, A.3    Simon, M.C.4    Maltepe, E.5
  • 73
    • 27944461698 scopus 로고    scopus 로고
    • Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation
    • Cowden Dahl KD, Fryer BH, Mack FA, et al. Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation. Mol Cell Biol 2005; 25: 10479-91.
    • (2005) Mol Cell Biol , vol.25 , pp. 10479-10491
    • Cowden Dahl, K.D.1    Fryer, B.H.2    Mack, F.A.3
  • 74
    • 33644747418 scopus 로고    scopus 로고
    • HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth
    • Covello KL, Kehler J, Yu H, et al. HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 2006; 20: 557-70.
    • (2006) Genes Dev , vol.20 , pp. 557-570
    • Covello, K.L.1    Kehler, J.2    Yu, H.3
  • 75
    • 0035887011 scopus 로고    scopus 로고
    • FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
    • Mahon PC, Hirota K, Semenza GL. FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev 2001; 15: 2675-86.
    • (2001) Genes Dev , vol.15 , pp. 2675-2686
    • Mahon, P.C.1    Hirota, K.2    Semenza, G.L.3
  • 76
    • 0029859510 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension
    • Jiang BH, Semenza GL, Bauer C, Marti HH. Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. Am J Physiol 1996; 271: C1172-80.
    • (1996) Am J Physiol , vol.271
    • Jiang, B.H.1    Semenza, G.L.2    Bauer, C.3    Marti, H.H.4
  • 77
    • 0037315337 scopus 로고    scopus 로고
    • Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs
    • Wiesener MS, Jurgensen JS, Rosenberger C, et al. Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. FASEB J 2003; 17: 271-73.
    • (2003) FASEB J , vol.17 , pp. 271-273
    • Wiesener, M.S.1    Jurgensen, J.S.2    Rosenberger, C.3
  • 78
    • 0035159670 scopus 로고    scopus 로고
    • HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
    • Stroka DM, Burkhardt T, Desbaillets I, et al. HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J 2001; 15: 2445-53.
    • (2001) FASEB J , vol.15 , pp. 2445-2453
    • Stroka, D.M.1    Burkhardt, T.2    Desbaillets, I.3
  • 79
    • 0034682513 scopus 로고    scopus 로고
    • The transcription factor EPAS-1/hypoxia-inducible factor 2 plays an important role in vascular remodeling
    • Peng J, Zhang L, Drysdale L, Fong GH. The transcription factor EPAS-1/hypoxia-inducible factor 2 plays an important role in vascular remodeling. Proc Natl Acad Sci USA 2000; 97: 8386-91.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8386-8391
    • Peng, J.1    Zhang, L.2    Drysdale, L.3    Fong, G.H.4
  • 80
    • 0041859213 scopus 로고    scopus 로고
    • Effect of maternal chronic hypoxic exposure during gestation on apoptosis in fetal rat heart
    • Bae S, Xiao Y, Li G, Casiano CA, Zhang L. Effect of maternal chronic hypoxic exposure during gestation on apoptosis in fetal rat heart. Am J Physiol Heart Circ Physiol 2003; 285: H983-90.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Bae, S.1    Xiao, Y.2    Li, G.3    Casiano, C.A.4    Zhang, L.5
  • 81
    • 0031587432 scopus 로고    scopus 로고
    • Cardiac expressions of HIF-1 alpha and HLF/EPAS, two basic loop helix/PAS domain transcription factors involved in adaptative responses to hypoxic stresses
    • Ladoux A, Frelin C. Cardiac expressions of HIF-1 alpha and HLF/EPAS, two basic loop helix/PAS domain transcription factors involved in adaptative responses to hypoxic stresses. Biochem Biophys Res Commun 1997; 240: 552-56.
    • (1997) Biochem Biophys Res Commun , vol.240 , pp. 552-556
    • Ladoux, A.1    Frelin, C.2
  • 82
    • 40349103416 scopus 로고    scopus 로고
    • Formation of large coronary arteries by cardiac progenitor cells
    • Tillmanns J, Rota M, Hosoda T, et al. Formation of large coronary arteries by cardiac progenitor cells. Proc Natl Acad Sci USA 2008; 105: 1668-73.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 1668-1673
    • Tillmanns, J.1    Rota, M.2    Hosoda, T.3
  • 83
    • 33645795743 scopus 로고    scopus 로고
    • HIF-1alpha-targeted pathways are activated by heat acclimation and contribute to acclimation-ischemic cross-tolerance in the heart
    • Maloyan A, Eli-Berchoer L, Semenza GL, Gerstenblith G, Stern MD, Horowitz M. HIF-1alpha-targeted pathways are activated by heat acclimation and contribute to acclimation-ischemic cross-tolerance in the heart. Physiol Genomics 2005; 23: 79-88.
    • (2005) Physiol Genomics , vol.23 , pp. 79-88
    • Maloyan, A.1    Eli-Berchoer, L.2    Semenza, G.L.3    Gerstenblith, G.4    Stern, M.D.5    Horowitz, M.6
  • 84
    • 1842416574 scopus 로고    scopus 로고
    • Oxygen(es) and the hypoxia-inducible factor-1
    • Wenger RH, Gassmann M. Oxygen(es) and the hypoxia-inducible factor-1. Biol Chem 1997; 378: 609-16.
    • (1997) Biol Chem , vol.378 , pp. 609-616
    • Wenger, R.H.1    Gassmann, M.2
  • 85
    • 33846199233 scopus 로고    scopus 로고
    • Hypoxia-inducible factors: Central regulators of the tumor phenotype
    • Gordan JD, Simon MC. Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr Opin Genet Dev 2007; 17: 71-7.
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 71-77
    • Gordan, J.D.1    Simon, M.C.2
  • 86
    • 4644226319 scopus 로고    scopus 로고
    • A unique pathway of cardiac myocyte death caused by hypoxia-acidosis
    • Graham RM, Frazier DP, Thompson JW, et al. A unique pathway of cardiac myocyte death caused by hypoxia-acidosis. J Exp Biol 2004; 207: 3189-200.
    • (2004) J Exp Biol , vol.207 , pp. 3189-3200
    • Graham, R.M.1    Frazier, D.P.2    Thompson, J.W.3
  • 87
    • 59749100272 scopus 로고    scopus 로고
    • Prodeath or prosurvival: Two facets of hypoxia inducible factor-1 in perinatal brain injury
    • Chen W, Ostrowski RP, Obenaus A, Zhang JH. Prodeath or prosurvival: two facets of hypoxia inducible factor-1 in perinatal brain injury. Exp Neurol 2009; 216: 7-15.
    • (2009) Exp Neurol , vol.216 , pp. 7-15
    • Chen, W.1    Ostrowski, R.P.2    Obenaus, A.3    Zhang, J.H.4
  • 88
    • 0032238419 scopus 로고    scopus 로고
    • Human adaptation to high altitude: Regional and life-cycle perspectives
    • Moore LG, Niermeyer S, Zamudio S: Human adaptation to high altitude: regional and life-cycle perspectives. Am J Phys Anthropol 1998; Suppl 27: 25-64.
    • (1998) Am J Phys Anthropol , Issue.SUPPL. 27 , pp. 25-64
    • Moore, L.G.1    Niermeyer, S.2    Zamudio, S.3
  • 89
    • 0041629286 scopus 로고    scopus 로고
    • The placenta at high altitude
    • Zamudio S. The placenta at high altitude. High Alt Med Biol 2003; 4: 171-91.
    • (2003) High Alt Med Biol , vol.4 , pp. 171-191
    • Zamudio, S.1
  • 90
    • 0030802218 scopus 로고    scopus 로고
    • The effect of high altitude and other risk factors on birthweight: Independent or interactive effects?
    • Jensen GM, Moore LG. The effect of high altitude and other risk factors on birthweight: independent or interactive effects? Am J Public health 1997; 87: 1003-7.
    • (1997) Am J Public Health , vol.87 , pp. 1003-1007
    • Jensen, G.M.1    Moore, L.G.2
  • 92
    • 0041629292 scopus 로고    scopus 로고
    • Fetal growth restriction and maternal oxygen transport during high altitude pregnancy
    • Moore LG. Fetal growth restriction and maternal oxygen transport during high altitude pregnancy. High Alt Med Biol 2003; 4: 141-56.
    • (2003) High Alt Med Biol , vol.4 , pp. 141-156
    • Moore, L.G.1
  • 93
    • 0024542325 scopus 로고
    • Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease
    • Barker DJ, Osmond C, Golding J, Kuh D, Wadsworth ME. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ 1989; 298: 564-67.
    • (1989) BMJ , vol.298 , pp. 564-567
    • Barker, D.J.1    Osmond, C.2    Golding, J.3    Kuh, D.4    Wadsworth, M.E.5
  • 94
    • 0027999461 scopus 로고
    • Outcome of low birthweight
    • Barker DJ. Outcome of low birthweight. Horm Res 1994; 42: 223-30.
    • (1994) Horm Res , vol.42 , pp. 223-230
    • Barker, D.J.1
  • 95
    • 0030991824 scopus 로고    scopus 로고
    • Fetal nutrition and cardiovascular disease in later life
    • Barker DJ. Fetal nutrition and cardiovascular disease in later life. Br Med Bull 1997; 53: 96-108.
    • (1997) Br Med Bull , vol.53 , pp. 96-108
    • Barker, D.J.1
  • 96
    • 11144288674 scopus 로고    scopus 로고
    • Prenatal hypoxia and cardiac programming
    • Zhang L. Prenatal hypoxia and cardiac programming. J Soc Gynecol Investig 2005; 12: 2-13.
    • (2005) J Soc Gynecol Investig , vol.12 , pp. 2-13
    • Zhang, L.1
  • 98
    • 0028940132 scopus 로고
    • Chronic maternal hypoxia retards fetal growth and increases glucose utilization of select fetal tissues in the rat
    • Lueder FL, Kim SB, Buroker CA, Bangalore SA, Ogata ES. Chronic maternal hypoxia retards fetal growth and increases glucose utilization of select fetal tissues in the rat. Metabolism 1995; 44: 532-7.
    • (1995) Metabolism , vol.44 , pp. 532-537
    • Lueder, F.L.1    Kim, S.B.2    Buroker, C.A.3    Bangalore, S.A.4    Ogata, E.S.5
  • 101
    • 0031957221 scopus 로고    scopus 로고
    • Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1
    • Martin C, Yu AY, Jiang BH, et al. Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1. Am J Obstet Gynecol 1998; 178: 527-34.
    • (1998) Am J Obstet Gynecol , vol.178 , pp. 527-534
    • Martin, C.1    Yu, A.Y.2    Jiang, B.H.3
  • 103
    • 0033772467 scopus 로고    scopus 로고
    • Chronic hypoxia and developmental regulation of cytochrome c expression in rats
    • Xiao D, Ducsay CA, Zhang L. Chronic hypoxia and developmental regulation of cytochrome c expression in rats. J Soc Gynecol Investig 2000; 7: 279-83.
    • (2000) J Soc Gynecol Investig , vol.7 , pp. 279-283
    • Xiao, D.1    Ducsay, C.A.2    Zhang, L.3
  • 104
    • 0026054753 scopus 로고
    • Fetal response to intrauterine stress
    • discussion 29-37
    • Thornburg KL. Fetal response to intrauterine stress. Ciba Found Symp 1991; 156: 17-29; discussion 29-37.
    • (1991) Ciba Found Symp , vol.156 , pp. 17-29
    • Thornburg, K.L.1
  • 106
    • 0038104927 scopus 로고    scopus 로고
    • Catecholamines act via a beta-adrenergic receptor to maintain fetal heart rate and survival
    • Portbury AL, Chandra R, Groelle M, et al. Catecholamines act via a beta-adrenergic receptor to maintain fetal heart rate and survival. Am J Physiol Heart Circ Physiol 2003; 284: 2069-77.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , pp. 2069-2077
    • Portbury, A.L.1    Chandra, R.2    Groelle, M.3
  • 107
    • 0028284643 scopus 로고
    • Cardiac function in fetal sheep during two weeks of hypoxemia
    • Kamitomo M, Longo LD, Gilbert RD. Cardiac function in fetal sheep during two weeks of hypoxemia. Am J Physiol 1994; 266: R1778-85.
    • (1994) Am J Physiol , vol.266
    • Kamitomo, M.1    Longo, L.D.2    Gilbert, R.D.3
  • 108
    • 0036848551 scopus 로고    scopus 로고
    • Effects of long-term hypoxia and development on cardiac contractile proteins in fetal and adult sheep
    • Kamitomo M, Onishi J, Gutierrez I, Stiffel VM, Gilbert RD. Effects of long-term hypoxia and development on cardiac contractile proteins in fetal and adult sheep. J Soc Gynecol Investig 2002; 9: 335-41.
    • (2002) J Soc Gynecol Investig , vol.9 , pp. 335-341
    • Kamitomo, M.1    Onishi, J.2    Gutierrez, I.3    Stiffel, V.M.4    Gilbert, R.D.5
  • 110
    • 0030910649 scopus 로고    scopus 로고
    • Activator calcium and myocardial contractility in fetal sheep exposed to long-term high-altitude hypoxia
    • Browne VA, Stiffel VM, Pearce WJ, Longo LD, Gilbert RD. Activator calcium and myocardial contractility in fetal sheep exposed to long-term high-altitude hypoxia. Am J Physiol 1997; 272: H1196-1204.
    • (1997) Am J Physiol , vol.272
    • Browne, V.A.1    Stiffel, V.M.2    Pearce, W.J.3    Longo, L.D.4    Gilbert, R.D.5
  • 111
    • 0345736919 scopus 로고    scopus 로고
    • Effects of long-term high-altitude hypoxia and troponin I phosphorylation on cardiac myofilament calcium responses in fetal and nonpregnant sheep
    • Onishi J, Browne VA, Kono S, Stiffel VM, Gilbert RD. Effects of long-term high-altitude hypoxia and troponin I phosphorylation on cardiac myofilament calcium responses in fetal and nonpregnant sheep. J Soc Gynecol Investig 2004; 11: 1-8.
    • (2004) J Soc Gynecol Investig , vol.11 , pp. 1-8
    • Onishi, J.1    Browne, V.A.2    Kono, S.3    Stiffel, V.M.4    Gilbert, R.D.5
  • 112
    • 65249142202 scopus 로고    scopus 로고
    • Hypoxia induces dilated cardiomyopathy in the chick embryo: Mechanism, intervention, and long-term consequences
    • Tintu A, Rouwet E, Verlohren S, et al. Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences. PLoS One 2009; 4: e5155.
    • (2009) PLoS One , vol.e5155 , pp. 4
    • Tintu, A.1    Rouwet, E.2    Verlohren, S.3
  • 114
    • 33751322950 scopus 로고    scopus 로고
    • Arrhythmogenesis in the developing heart during anoxia-reoxygenation and hypothermia-rewarming: An in vitro model
    • Sarre A, Maury P, Kucera P, Kappenberger L, Raddatz E. Arrhythmogenesis in the developing heart during anoxia-reoxygenation and hypothermia-rewarming: an in vitro model. J Cardiovasc Electrophysiol 2006; 17: 1350-9.
    • (2006) J Cardiovasc Electrophysiol , vol.17 , pp. 1350-1359
    • Sarre, A.1    Maury, P.2    Kucera, P.3    Kappenberger, L.4    Raddatz, E.5
  • 115
    • 33947662567 scopus 로고    scopus 로고
    • Effect of hypoxia during early organogenesis on cardiac activity and noradrenergic regulation in the postnatal period
    • Graf AV, Maslova MV, Maklakova AS, et al. Effect of hypoxia during early organogenesis on cardiac activity and noradrenergic regulation in the postnatal period. Bull Exp Biol Med 2006; 142: 543-5.
    • (2006) Bull Exp Biol Med , vol.142 , pp. 543-545
    • Graf, A.V.1    Maslova, M.V.2    Maklakova, A.S.3
  • 116
    • 0022621648 scopus 로고
    • Infant mortality, childhood nutrition, and ischaemic heart disease in England and Wales
    • Barker DJ, Osmond C. Infant mortality, childhood nutrition, and ischaemic heart disease in England and Wales. Lancet 1986; 1: 1077-81.
    • (1986) Lancet , vol.1 , pp. 1077-1081
    • Barker, D.J.1    Osmond, C.2
  • 117
    • 0025081078 scopus 로고
    • The fetal and infant origins of adult disease
    • Barker DJ. The fetal and infant origins of adult disease. BMJ 1990; 301: 1111.
    • (1990) BMJ , vol.301 , pp. 1111
    • Barker, D.J.1
  • 118
    • 0026091454 scopus 로고
    • Programming by early nutrition in man
    • discussion 50-35
    • Lucas A. Programming by early nutrition in man. Ciba Found Symp 1991; 156: 38-50; discussion 50-35.
    • (1991) Ciba Found Symp , vol.156 , pp. 38-50
    • Lucas, A.1
  • 119
    • 0037674471 scopus 로고    scopus 로고
    • Effect of fetal hypoxia on heart susceptibility to ischemia and reperfusion injury in the adult rat
    • Li G, Xiao Y, Estrella JL, Ducsay CA, Gilbert RD, Zhang L. Effect of fetal hypoxia on heart susceptibility to ischemia and reperfusion injury in the adult rat. J Soc Gynecol Investig 2003; 10: 265-74.
    • (2003) J Soc Gynecol Investig , vol.10 , pp. 265-274
    • Li, G.1    Xiao, Y.2    Estrella, J.L.3    Ducsay, C.A.4    Gilbert, R.D.5    Zhang, L.6
  • 122
    • 0029068871 scopus 로고
    • Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
    • Nicholson DW, Ali A, Thornberry NA, et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995; 376: 37-43.
    • (1995) Nature , vol.376 , pp. 37-43
    • Nicholson, D.W.1    Ali, A.2    Thornberry, N.A.3
  • 123
    • 0033972729 scopus 로고    scopus 로고
    • Effect of caspase inhibitors on myocardial infarct size and myocyte DNA fragmentation in the ischemia-reperfused rat heart
    • Okamura T, Miura T, Takemura G, et al. Effect of caspase inhibitors on myocardial infarct size and myocyte DNA fragmentation in the ischemia-reperfused rat heart. Cardiovasc Res 2000; 45: 642-50.
    • (2000) Cardiovasc Res , vol.45 , pp. 642-650
    • Okamura, T.1    Miura, T.2    Takemura, G.3
  • 124
    • 33845637819 scopus 로고    scopus 로고
    • Hypoxia or nutrient restriction during pregnancy in rats leads to progressive cardiac remodeling and impairs postischemic recovery in adult male offspring
    • Xu Y, Williams SJ, O'Brien D, Davidge ST. Hypoxia or nutrient restriction during pregnancy in rats leads to progressive cardiac remodeling and impairs postischemic recovery in adult male offspring. FASEB J 2006; 20: 1251-3.
    • (2006) FASEB J , vol.20 , pp. 1251-1253
    • Xu, Y.1    Williams, S.J.2    O'Brien, D.3    Davidge, S.T.4
  • 125
    • 1942501659 scopus 로고    scopus 로고
    • Effect of prenatal hypoxia on heat stress-mediated cardioprotection in adult rat heart
    • Li G, Bae S, Zhang L. Effect of prenatal hypoxia on heat stress-mediated cardioprotection in adult rat heart. Am J Physiol Heart Circ Physiol 2004; 286: 1717-19.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286 , pp. 1717-1719
    • Li, G.1    Bae, S.2    Zhang, L.3
  • 126
    • 67651046198 scopus 로고    scopus 로고
    • Prenatal hypoxia causes a sex-dependent increase in heart susceptibility to ischemia and reperfusion injury in adult male offspring: Role of PKC{epsilon}
    • Xue Q, Zhang L. Prenatal hypoxia causes a sex-dependent increase in heart susceptibility to ischemia and reperfusion injury in adult male offspring: Role of PKC{epsilon}. J Pharmacol Exp Ther 2009; 330: 624-32.
    • (2009) J Pharmacol Exp Ther , vol.330 , pp. 624-632
    • Xue, Q.1    Zhang, L.2
  • 127
    • 0036023643 scopus 로고    scopus 로고
    • Targeted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts
    • Saurin AT, Pennington DJ, Raat NJ, Latchman DS, Owen MJ, Marber MS. Targeted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts. Cardiovasc Res 2002; 55: 672-80.
    • (2002) Cardiovasc Res , vol.55 , pp. 672-680
    • Saurin, A.T.1    Pennington, D.J.2    Raat, N.J.3    Latchman, D.S.4    Owen, M.J.5    Marber, M.S.6
  • 128
    • 0036177969 scopus 로고    scopus 로고
    • Formation of protein kinase C(epsilon)-Lck signaling modules confers cardioprotection
    • Ping P, Song C, Zhang J, et al. Formation of protein kinase C(epsilon)-Lck signaling modules confers cardioprotection. J Clin Invest 2002; 109: 499-507.
    • (2002) J Clin Invest , vol.109 , pp. 499-507
    • Ping, P.1    Song, C.2    Zhang, J.3
  • 129
    • 11244310899 scopus 로고    scopus 로고
    • Cardioprotection by epsilon-protein kinase C activation from ischemia: Continuous delivery and antiarrhythmic effect of an epsilon-protein kinase C-activating peptide
    • Inagaki K, Begley R, Ikeno F, Mochly-Rosen D. Cardioprotection by epsilon-protein kinase C activation from ischemia: continuous delivery and antiarrhythmic effect of an epsilon-protein kinase C-activating peptide. Circulation 2005; 111: 44-50.
    • (2005) Circulation , vol.111 , pp. 44-50
    • Inagaki, K.1    Begley, R.2    Ikeno, F.3    Mochly-Rosen, D.4
  • 130
    • 33646048801 scopus 로고    scopus 로고
    • Epsilon protein kinase C as a potential therapeutic target for the ischemic heart
    • Inagaki K, Churchill E, Mochly-Rosen D. Epsilon protein kinase C as a potential therapeutic target for the ischemic heart. Cardiovasc Res 2006; 70: 222-30.
    • (2006) Cardiovasc Res , vol.70 , pp. 222-230
    • Inagaki, K.1    Churchill, E.2    Mochly-Rosen, D.3
  • 131
    • 33745944232 scopus 로고    scopus 로고
    • Effect of perinatal hypoxia on cardiac tolerance to acute ischaemia in adult male and female rats
    • Netuka I, Szarszoi O, Maly J, et al. Effect of perinatal hypoxia on cardiac tolerance to acute ischaemia in adult male and female rats. Clin Exp Pharmacol Physiol 2006; 33: 714-9.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 714-719
    • Netuka, I.1    Szarszoi, O.2    Maly, J.3
  • 132
    • 70449644971 scopus 로고    scopus 로고
    • Changes of renal AT(1)/AT(2) receptors and structures in ovine fetuses following exposure to long-term hypoxia
    • Mao C, Hou J, Ge J, et al. Changes of renal AT(1)/AT(2) receptors and structures in ovine fetuses following exposure to long-term hypoxia. Am J Nephrol 2009; 31: 141-50.
    • (2009) Am J Nephrol , vol.31 , pp. 141-150
    • Mao, C.1    Hou, J.2    Ge, J.3
  • 133
    • 27844518760 scopus 로고    scopus 로고
    • Long-term hypoxia represses the expression of key genes regulating cortisol biosynthesis in the near-term ovine fetus
    • Myers DA, Hyatt K, Mlynarczyk M, Bird IM, Ducsay CA. Long-term hypoxia represses the expression of key genes regulating cortisol biosynthesis in the near-term ovine fetus. Am J Physiol Regul Integr Comp Physiol 2005; 289: R1707-14.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289
    • Myers, D.A.1    Hyatt, K.2    Mlynarczyk, M.3    Bird, I.M.4    Ducsay, C.A.5
  • 134
    • 0030444722 scopus 로고    scopus 로고
    • Dexamethasone in the last week of pregnancy attenuates hippocampal glucocorticoid receptor gene expression and elevates blood pressure in the adult offspring in the rat
    • Levitt NS, Lindsay RS, Holmes MC, Seckl JR. Dexamethasone in the last week of pregnancy attenuates hippocampal glucocorticoid receptor gene expression and elevates blood pressure in the adult offspring in the rat. Neuroendocrinology 1996; 64: 412-8.
    • (1996) Neuroendocrinology , vol.64 , pp. 412-418
    • Levitt, N.S.1    Lindsay, R.S.2    Holmes, M.C.3    Seckl, J.R.4
  • 135
    • 60749092460 scopus 로고    scopus 로고
    • Epigenetics and cancer without genomic instability
    • McKenna ES, Roberts CW. Epigenetics and cancer without genomic instability. Cell Cycle 2009; 8: 23-6.
    • (2009) Cell Cycle , vol.8 , pp. 23-26
    • McKenna, E.S.1    Roberts, C.W.2
  • 138
    • 62149130042 scopus 로고    scopus 로고
    • Fetal exposure to cocaine causes programming of Prkce gene repression in the left ventricle of adult rat offspring
    • Zhang H, Meyer KD, Zhang L. Fetal exposure to cocaine causes programming of Prkce gene repression in the left ventricle of adult rat offspring. Biol Reprod 2009; 80: 440-8.
    • (2009) Biol Reprod , vol.80 , pp. 440-448
    • Zhang, H.1    Meyer, K.D.2    Zhang, L.3
  • 139
    • 69249202563 scopus 로고    scopus 로고
    • Direct effect of cocaine on epigenetic regulation of PKCvarepsilon gene repression in the fetal rat heart
    • Meyer K, Zhang H, Zhang L: Direct effect of cocaine on epigenetic regulation of PKCvarepsilon gene repression in the fetal rat heart. J Mol Cell Cardiol 2009; 47: 352-8
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 352-358
    • Meyer, K.1    Zhang, H.2    Zhang, L.3
  • 140
    • 19444378371 scopus 로고    scopus 로고
    • Prenatal cocaine exposure increases heart susceptibility to ischaemia-reperfusion injury in adult male but not female rats
    • Bae S, Gilbert RD, Ducsay CA, Zhang L. Prenatal cocaine exposure increases heart susceptibility to ischaemia-reperfusion injury in adult male but not female rats. J Physiol 2005; 565: 149-58.
    • (2005) J Physiol , vol.565 , pp. 149-158
    • Bae, S.1    Gilbert, R.D.2    Ducsay, C.A.3    Zhang, L.4
  • 141
    • 66149092966 scopus 로고    scopus 로고
    • Prenatal cocaine exposure abolished ischemic preconditioning-induced protection in adult male rat hearts: Role of PKC{varepsilon}
    • Meyer KD Zhang H, Zhang L. Prenatal cocaine exposure abolished ischemic preconditioning-induced protection in adult male rat hearts: role of PKC{varepsilon}. Am J Physiol Heart Circ Physiol 2009; 296: H1566-76.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Meyer, K.D.1    Zhang, H.2    Zhang, L.3
  • 142
    • 33646709444 scopus 로고    scopus 로고
    • Epigenetic regulation of stem cell differentiation
    • Wu H, Sun YE. Epigenetic regulation of stem cell differentiation. Pediatr Res 2006; 59: 21R-5R.
    • (2006) Pediatr Res , vol.59
    • Wu, H.1    Sun, Y.E.2
  • 143
    • 24344502368 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-dependent histone deacetylase activity determines stem cell fate in the placenta
    • Maltepe E, Krampitz GW, Okazaki KM, et al. Hypoxia-inducible factor-dependent histone deacetylase activity determines stem cell fate in the placenta. Development 2005; 132: 3393-403.
    • (2005) Development , vol.132 , pp. 3393-3403
    • Maltepe, E.1    Krampitz, G.W.2    Okazaki, K.M.3
  • 144
  • 145
    • 0024993603 scopus 로고
    • Oct-6: A POU transcription factor expressed in embryonal stem cells and in the developing brain
    • Suzuki N, Rohdewohld H, Neuman T, Gruss P, Scholer HR. Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain. EMBO J 1990, 9: 3723-32.
    • (1990) EMBO J , vol.9 , pp. 3723-3732
    • Suzuki, N.1    Rohdewohld, H.2    Neuman, T.3    Gruss, P.4    Scholer, H.R.5
  • 146
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
    • Nichols J, Zevnik B, Anastassiadis K, et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998; 95: 379-91.
    • (1998) Cell , vol.95 , pp. 379-391
    • Nichols, J.1    Zevnik, B.2    Anastassiadis, K.3
  • 147
    • 0036528246 scopus 로고    scopus 로고
    • Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
    • Kondo K, Klco J, Nakamura E, Lechpammer M, Kaelin WG Jr. Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein. Cancer Cell 2002; 1: 237-46.
    • (2002) Cancer Cell , vol.1 , pp. 237-246
    • Kondo, K.1    Klco, J.2    Nakamura, E.3    Lechpammer, M.4    Kaelin, W.G.5
  • 148
    • 56849096837 scopus 로고    scopus 로고
    • HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma
    • Gordan JD, Lal P, Dondeti VR, et al. HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma. Cancer Cell 2008; 14: 435-46.
    • (2008) Cancer Cell , vol.14 , pp. 435-446
    • Gordan, J.D.1    Lal, P.2    Dondeti, V.R.3
  • 149
    • 61349088682 scopus 로고    scopus 로고
    • The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF
    • Beyer S, Kristensen MM, Jensen KS, Johansen JV, Staller P. The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF. J Biol Chem 2008; 283: 36542-52.
    • (2008) J Biol Chem , vol.283 , pp. 36542-36552
    • Beyer, S.1    Kristensen, M.M.2    Jensen, K.S.3    Johansen, J.V.4    Staller, P.5
  • 150
    • 45449110185 scopus 로고    scopus 로고
    • Hypoxia upregulates the histone demethylase JMJD1A via HIF-1
    • Wellmann S, Bettkober M, Zelmer A, et al. Hypoxia upregulates the histone demethylase JMJD1A via HIF-1. Biochem Biophys Res Commun 2008; 372: 892-7.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 892-897
    • Wellmann, S.1    Bettkober, M.2    Zelmer, A.3
  • 151
    • 33749494456 scopus 로고    scopus 로고
    • Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells
    • Chen H, Yan Y, Davidson TL, Shinkai Y, Costa M. Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells. Cancer Res 2006; 66: 9009-16.
    • (2006) Cancer Res , vol.66 , pp. 9009-9016
    • Chen, H.1    Yan, Y.2    Davidson, T.L.3    Shinkai, Y.4    Costa, M.5
  • 152
    • 0034676331 scopus 로고    scopus 로고
    • Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function
    • Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function. Oncogene 2000; 19: 5435-43.
    • (2000) Oncogene , vol.19 , pp. 5435-5443
    • Krieg, M.1    Haas, R.2    Brauch, H.3    Acker, T.4    Flamme, I.5    Plate, K.H.6
  • 153
    • 54049090410 scopus 로고    scopus 로고
    • Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice
    • Granger A, Abdullah I, Huebner F, et al. Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice. FASEB J 2008; 22: 3549-60.
    • (2008) FASEB J , vol.22 , pp. 3549-3560
    • Granger, A.1    Abdullah, I.2    Huebner, F.3
  • 154
    • 70349518921 scopus 로고    scopus 로고
    • Epigenetic regulation of Myc on retinoic acid receptor beta and PDLIM4 in RWPE1 cells
    • He M, Vanaja DK, Karnes RJ, Young CY. Epigenetic regulation of Myc on retinoic acid receptor beta and PDLIM4 in RWPE1 cells. Prostate 2009; 69: 1643-50.
    • (2009) Prostate , vol.69 , pp. 1643-1650
    • He, M.1    Vanaja, D.K.2    Karnes, R.J.3    Young, C.Y.4
  • 155
    • 13444270415 scopus 로고    scopus 로고
    • Myc represses transcription through recruitment of DNA methyltransferase corepressor
    • Brenner C, Deplus R, Didelot C, et al. Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J 2005; 24: 336-46.
    • (2005) EMBO J , vol.24 , pp. 336-346
    • Brenner, C.1    Deplus, R.2    Didelot, C.3
  • 157
    • 0034682786 scopus 로고    scopus 로고
    • Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: A mechanism of O2 sensing
    • Chandel NS, McClintock DS, Feliciano CE, et al. Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing. J Biol Chem 2000; 275: 25130-8.
    • (2000) J Biol Chem , vol.275 , pp. 25130-25138
    • Chandel, N.S.1    McClintock, D.S.2    Feliciano, C.E.3
  • 158
    • 69849097192 scopus 로고    scopus 로고
    • Mitochondrial generation of free radicals and hypoxic signaling
    • Poyton RO, Ball KA, Castello PR. Mitochondrial generation of free radicals and hypoxic signaling. Trends Endocrinol Metab 2009; 20: 332-40.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 332-340
    • Poyton, R.O.1    Ball, K.A.2    Castello, P.R.3
  • 159
    • 57649221592 scopus 로고    scopus 로고
    • Hypoxic reactive oxygen species regulate the integrated stress response and cell survival
    • Liu L, Wise DR, Diehl JA, Simon MC. Hypoxic reactive oxygen species regulate the integrated stress response and cell survival. J Biol Chem 2008; 283: 31153-62.
    • (2008) J Biol Chem , vol.283 , pp. 31153-31162
    • Liu, L.1    Wise, D.R.2    Diehl, J.A.3    Simon, M.C.4
  • 160
    • 28844441670 scopus 로고    scopus 로고
    • Reactive oxygen species as signaling molecules in cardiovascular differentiation of embryonic stem cells and tumor-induced angiogenesis
    • Sauer H, Wartenberg M. Reactive oxygen species as signaling molecules in cardiovascular differentiation of embryonic stem cells and tumor-induced angiogenesis. Antioxid Redox Signal 2005; 7: 1423-34.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1423-1434
    • Sauer, H.1    Wartenberg, M.2
  • 161
    • 57249103576 scopus 로고    scopus 로고
    • Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: Methylation of the E-cadherin promoter
    • Lim SO, Gu JM, Kim MS, et al. Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter. Gastroenterology 2008; 135: 2128-40, 2140.e1-8.
    • (2008) Gastroenterology , vol.135
    • Lim, S.O.1    Gu, J.M.2    Kim, M.S.3
  • 162
    • 4644317883 scopus 로고    scopus 로고
    • Hypoxic reduction in cellular glutathione levels requires mitochondrial reactive oxygen species
    • Mansfield KD, Simon MC, Keith B. Hypoxic reduction in cellular glutathione levels requires mitochondrial reactive oxygen species. J Appl Physiol 2004; 97: 1358-66.
    • (2004) J Appl Physiol , vol.97 , pp. 1358-1366
    • Mansfield, K.D.1    Simon, M.C.2    Keith, B.3
  • 163
    • 0025791965 scopus 로고
    • Morphological, biochemical, and electrophy-siological characterization of a clonal cell (H9c2) line from rat heart
    • Hescheler J, Meyer R, Plant S, Krautwurst D, Rosenthal W, Schultz G: Morphological, biochemical, and electrophy-siological characterization of a clonal cell (H9c2) line from rat heart. Circ Res 1991; 69: 1476-86.
    • (1991) Circ Res , vol.69 , pp. 1476-1486
    • Hescheler, J.1    Meyer, R.2    Plant, S.3    Krautwurst, D.4    Rosenthal, W.5    Schultz, G.6
  • 164
    • 20944449676 scopus 로고    scopus 로고
    • Cardioprotective stress response in the human fetal heart
    • Coles JG, Boscarino C, Takahashi M, et al. Cardioprotective stress response in the human fetal heart. J Thorac Cardiovasc Surg 2005; 129: 1128-36.
    • (2005) J Thorac Cardiovasc Surg , vol.129 , pp. 1128-1136
    • Coles, J.G.1    Boscarino, C.2    Takahashi, M.3
  • 165
    • 41349117592 scopus 로고    scopus 로고
    • Hypoxia-induced compensatory effect as related to Shh and HIF-1alpha in ischemia embryo rat heart
    • Hwang JM, Weng YJ, Lin JA, et al. Hypoxia-induced compensatory effect as related to Shh and HIF-1alpha in ischemia embryo rat heart. Mol Cell Biochem 2008; 311: 179-87.
    • (2008) Mol Cell Biochem , vol.311 , pp. 179-187
    • Hwang, J.M.1    Weng, Y.J.2    Lin, J.A.3
  • 166
    • 0032031631 scopus 로고    scopus 로고
    • Stable overexpression of the constitutive form of heat shock protein 70 confers oxidative protection
    • Chong KY, Lai CC, Lille S, Chang C, Su CY. Stable overexpression of the constitutive form of heat shock protein 70 confers oxidative protection. J Mol Cell Cardiol 1998; 30: 599-608.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 599-608
    • Chong, K.Y.1    Lai, C.C.2    Lille, S.3    Chang, C.4    Su, C.Y.5


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