Catecholamines act via a β-adrenergic receptor to maintain fetal heart rate and survival

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 284, Issue 6 53-6, 2003, Pages

  Portbury, Andrea L ^a   Chandra, Rashmi ^a   Groelle, Marybeth ^a   McMillian, Michael K ^a   Elias, Alana ^a   Herlong, James R ^a   Rios, Maribel ^b   Roffler Tarlov, Suzanne ^b   Chikaraishi, Dona M ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adrenoreceptor; Dopamine hydroxylase; Hypoxia; Norepinephrine; Tyrosine hydroxylase

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; BUPRANOLOL; CATECHOLAMINE; DOPAMINE BETA MONOOXYGENASE; DRINKING WATER; ISOPRENALINE; NORADRENALIN; PHENTOLAMINE; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; DOSE RESPONSE; ECHOCARDIOGRAPHY; EMBRYO DEVELOPMENT; FEMALE; FETUS; FETUS HEART RATE; HYPOXIA; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXYGENATION; PREGNANCY; PRIORITY JOURNAL; STEREOSPECIFICITY; SURVIVAL; WILD TYPE;

EID: 0038104927     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00588.2002     Document Type: Article

References (40)

1. Blin N, Nahmias C, Drumare MF, and Strosberg AD. Mediation of most atypical effects by species homologues of the beta3-adrenoceptor. Br J Pharmacol 112: 911-919, 1994.
2. Bolden C, Cusack B, and Richelson E. Clozapine is a potent and selective muscarinic antagonist at the five cloned human muscarinic acetylcholine receptors expressed in CHO-K1 cells. Eur J Pharmacol 192: 205-206, 1991.
3. Butters L, Kennedy S, and Rubin PC. Atenolol in essential hypertension during pregnancy. Br Med J 301: 587-589, 1990.
4. Chen FC, Yamamura HI, and Roeske WR. Adenylate cyclase and beta adrenergic receptor development in the mouse heart. J Pharmacol Exp Ther 222: 7-13, 1982.
5. Chen FM, Yamamura HI, and Roeske WR. Ontogeny of mammalian myocardial beta-adrenergic receptors. Eur J Pharmacol 58: 255-264, 1979.
6. Cheng Y and Prusoff WH. Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (I5o) of an enzymatic reaction. Biochem Pharmacol 22: 3099-3108, 1973.
7. Cockroft DL. Dissection and culture of postimplantation embryos. In: Postimplantation Mammalian Embryos: A Practical Approach, edited by Copp AJ and Cockroft DL. Oxford, UK: IRL, 1990, p. 15-39.
8. Conolly ME, Davies DS, Dollery CT, Morgan CD, Paterson JW, and Sandler M. Metabolism of isoprenaline in dog and man. Br J Pharmacol 46: 458-472, 1972.
9. Cotecchia S, Schwinn DA, Randall RR, Lefkowitz RJ, Caron MG, and Kobilka BK. Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. Proc Natl Acad Sci USA 85: 7159-7163, 1988.
10. Ebert SN, Baden JM, Mathers LH, Siddall BJ, and Wong DL. Expression of phenylethanolamine N-methyltransferase in the embryonic rat heart. J Mol Cell Cardiol 28: 1653-1658, 1996.
11. Ebert SN and Thompson RP. Embryonic epinephrine synthesis in the rat heart before innervation: association with pacemaking and conduction tissue development. Circ Res 88: 117-124, 2001.
12. Gauthier C, Tavernier G, Trochu JN, Leblais V, Laurent K, Langin D, Escande D, and Le Marec H. Interspecies differences in the cardiac negative inotropic effects of beta(3)-adrenoceptor agonists. J Pharmacol Exp Ther 290: 687-693, 1999.
13. Gui YH, Linask KK, Khowsathit P, and Huhta JC. Doppler echocardiography of normal and abnormal embryonic mouse heart. Pediatr Res 40: 633-642, 1996.
14. 2+ mobilization in mouse peritoneal macrophages. Life Sci 53: 135-140, 1993.
15. Harrison JK, D'Angelo DD, Zeng DW, and Lynch KR. Pharmacological characterization of rat alpha 2-adrenergic receptors. Mol Pharmacol 40: 407-412, 1991.
16. Jensen A and Berger R. Fetal circulatory responses to oxygen lack. J Dev Physiol 16: 181-207, 1991.
17. Jones CT and Robinson RO. Plasma catecholamines in foetal and adult sheep. J Physiol 248: 15-33, 1975.
18. Kaumann AJ. Four beta-adrenoceptor subtypes in the mammalian heart. Trends Pharmacol Sci 18: 70-76, 1997 (erratum: Trends Pharmacol Sci 18: 181, 1997).
19. Kobayashi K, Morita S, Sawada H, Mizuguchi T, Yamada K, Nagatsu I, Hata T, Watanabe Y, Fujita K, and Nagatsu T. Targeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice. J Biol Chem 270: 27235-27243, 1995.
20. Kudlacz EM, Navarro HA, Eylers JP, and Slotkin TA. Prenatal exposure to propranolol via continuous maternal infusion: effects on physiological and biochemical processes mediated by beta adrenergic receptors in fetal and neonatal rat lung. J Pharmacol Exp Ther 252: 42-50, 1990.
21. Lagercrantz H and Bistoletti P. Catecholamine release in the newborn infant at birth. Pediatr Res 11: 889-893, 1977.
22. New DA and Coppola PT. Development of explanted rat fetuses in hyperbaric oxygen. Teratology 3: 153-161, 1970.
23. New DA and Coppola PT. Effects of different oxygen concentrations on the development of rat embryos in culture. J Reprod Fertil 21: 109-118, 1970.
24. Pattyn A, Goridis C, and Brunet JF. Specification of the central noradrenergic phenotype by the homeobox gene Phox2b. Mol Cell Neurosci 15: 235-243, 2000.
25. Pattyn A, Morin X, Cremer H, Goridis C, and Brunet JF. The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature 399: 366-370, 1999.
26. Rios M, Habecker B, Sasaoka T, Eisenhofer G, Tian H, Landis S, Chikaraishi D, and Roffler-Tarlov S. Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase. J Neurosci 19: 3519-3526, 1999.
27. Robkin M, Shepard TH, and Baum D. Autonomic drug effects on the heart rate of early rat embryos. Teratology 9: 35-44, 1974.
28. Roffler-Tarlov S and Rios M. Catecholamines before nervous activity. In: Handbook of Brain and Behavior in Human Development, edited by Kalvervoer AF and Gramsbergen A. London: Kluwer, 2001, p. 1-20.
29. Rychkov GY, Adams MB, McMillen IC, and Roberts ML. Oxygen-sensing mechanisms are present in the chromaffin cells of the sheep adrenal medulla before birth. J Physiol 509: 887-893, 1998.
30. Seidler FJ and Slotkin TA. Adrenomedullary function in the neonatal rat: responses to acute hypoxia. J Physiol 358: 1-16, 1985.
31. Slotkin TA. Endocrine control of synaptic development in the sympathetic nervous system: the cardiac-sympathetic axis. In: Developmental Neurobiology of the Autonomic Nervous System, edited by Gootman PM. Clifton, NJ: Humana, 1986, p. 97-133.
32. Slotkin TA and Seidler FJ. Adrenomedullary catecholamine release in the fetus and newborn: secretory mechanisms and their role in stress and survival. J Dev Physiol 10: 1-16, 1988.
33. Thomas SA, Matsumoto AM, and Palmiter RD. Noradrenaline is essential for mouse fetal development. Nature 374: 643-646, 1995.
34. Van der Weyden GC, Taverne MA, Dieleman SJ, Wurth Y, Bevers MM, and van Oord HA. Physiological aspects of pregnancy and parturition in dogs. J Reprod Fertil 39, Suppl: 211-224, 1989.
35. Von Dadelszen P, Ornstein MP, Bull SB, Logan AG, Koren G, and Magee LA. Fall in mean arterial pressure and fetal growth restriction in pregnancy hypertension: a meta-analysis. Lancet 355: 87-92, 2000.
36. Wellstein A, Palm D, and Belz GG. Affinity and selectivity of beta- adrenoceptor antagonists in vitro. J Cardiovasc Pharmacol 8, Suppl: S36-S40, 1986.
37. Woudstra BR, Kim C, Aarnoudse JG, and Nathanielsz PW. Myometrial contracture-related increases in plasma adrenocorticotropin in fetal sheep in the last third of gestation are abolished by maintaining fetal normoxemia. Endocrinology 129: 1709-1713, 1991.
38. Yavarone MS, Shuey DL, Tamir H, Sadler TW, and Lauder JM. Serotonin and cardiac morphogenesis in the mouse embryo. Teratology 47: 573-584, 1993.
39. Zhou QY and Palmiter RD. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell 83: 1197-1209, 1995.
40. Zhou QY, Quaife CJ, and Palmiter RD. Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. Nature 374: 640-643, 1995.