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Volumn 216, Issue 1, 2009, Pages 7-15

Prodeath or prosurvival: Two facets of hypoxia inducible factor-1 in perinatal brain injury

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; ENDOTHELIN 1; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE;

EID: 59749100272     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2008.10.016     Document Type: Review
Times cited : (76)

References (122)
  • 1
    • 33646119185 scopus 로고    scopus 로고
    • Expression of the gene encoding the pro-apoptotic BNIP3 protein and stimulation of hypoxia-inducible factor-1alpha (HIF-1alpha) protein following focal cerebral ischemia in rats
    • Althaus J., Bernaudin M., Petit E., Toutain J., Touzani O., and Rami A. Expression of the gene encoding the pro-apoptotic BNIP3 protein and stimulation of hypoxia-inducible factor-1alpha (HIF-1alpha) protein following focal cerebral ischemia in rats. Neurochem. Int. 48 (2006) 687-695
    • (2006) Neurochem. Int. , vol.48 , pp. 687-695
    • Althaus, J.1    Bernaudin, M.2    Petit, E.3    Toutain, J.4    Touzani, O.5    Rami, A.6
  • 2
    • 13544251744 scopus 로고    scopus 로고
    • Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line
    • Aminova L.R., Chavez J.C., Lee J., Ryu H., Kung A., LaManna J.C., and Ratan R.R. Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line. J. Biol. Chem. 280 (2005) 3996-4003
    • (2005) J. Biol. Chem. , vol.280 , pp. 3996-4003
    • Aminova, L.R.1    Chavez, J.C.2    Lee, J.3    Ryu, H.4    Kung, A.5    LaManna, J.C.6    Ratan, R.R.7
  • 3
    • 33750342490 scopus 로고    scopus 로고
    • Induced angiogenesis under cerebral ischemia by cyclooxygenase 2 and hypoxia-inducible factor naked DNA in a rat indirect-bypass model
    • Anan M., Abe T., Matsuda T., Ishii K., Kamida T., Fujiki M., and Kobayashi H. Induced angiogenesis under cerebral ischemia by cyclooxygenase 2 and hypoxia-inducible factor naked DNA in a rat indirect-bypass model. Neurosci. Lett. 409 (2006) 118-123
    • (2006) Neurosci. Lett. , vol.409 , pp. 118-123
    • Anan, M.1    Abe, T.2    Matsuda, T.3    Ishii, K.4    Kamida, T.5    Fujiki, M.6    Kobayashi, H.7
  • 4
    • 33846999907 scopus 로고    scopus 로고
    • Comparison of two neonatal ischemic injury models using magnetic resonance imaging
    • Ashwal S., Tone B., Tian H.R., Chong S., and Obenaus A. Comparison of two neonatal ischemic injury models using magnetic resonance imaging. Pediatr. Res. 61 (2007) 9-14
    • (2007) Pediatr. Res. , vol.61 , pp. 9-14
    • Ashwal, S.1    Tone, B.2    Tian, H.R.3    Chong, S.4    Obenaus, A.5
  • 5
    • 34548119130 scopus 로고    scopus 로고
    • Temporal and regional evolution of aquaporin-4 expression and magnetic resonance imaging in a rat pup model of neonatal stroke
    • Badaut J., Ashwal S., Tone B., Regli L., Tian H.R., and Obenaus A. Temporal and regional evolution of aquaporin-4 expression and magnetic resonance imaging in a rat pup model of neonatal stroke. Pediatr. Res. 62 (2007) 248-254
    • (2007) Pediatr. Res. , vol.62 , pp. 248-254
    • Badaut, J.1    Ashwal, S.2    Tone, B.3    Regli, L.4    Tian, H.R.5    Obenaus, A.6
  • 6
    • 0035449358 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity
    • Bal-Price A., and Brown G.C. Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity. J. Neurosci. 21 (2001) 6480-6491
    • (2001) J. Neurosci. , vol.21 , pp. 6480-6491
    • Bal-Price, A.1    Brown, G.C.2
  • 7
    • 34250021865 scopus 로고    scopus 로고
    • Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia
    • Baranova O., Miranda L.F., Pichiule P., Dragatsis I., Johnson R.S., and Chavez J.C. Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia. J. Neurosci. 27 (2007) 6320-6332
    • (2007) J. Neurosci. , vol.27 , pp. 6320-6332
    • Baranova, O.1    Miranda, L.F.2    Pichiule, P.3    Dragatsis, I.4    Johnson, R.S.5    Chavez, J.C.6
  • 8
    • 0030876019 scopus 로고    scopus 로고
    • Hypoxia-ischemia, but not hypoxia alone, induces the expression of heme oxygenase-1 (HSP32) in newborn rat brain
    • Bergeron M., Ferriero D.M., Vreman H.J., Stevenson D.K., and Sharp F.R. Hypoxia-ischemia, but not hypoxia alone, induces the expression of heme oxygenase-1 (HSP32) in newborn rat brain. J. Cereb. Blood Flow Metab. 17 (1997) 647-658
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 647-658
    • Bergeron, M.1    Ferriero, D.M.2    Vreman, H.J.3    Stevenson, D.K.4    Sharp, F.R.5
  • 9
    • 0033839757 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain
    • Bergeron M., Gidday J.M., Yu A.Y., Semenza G.L., Ferriero D.M., and Sharp F.R. Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain. Ann. Neurol. 48 (2000) 285-296
    • (2000) Ann. Neurol. , vol.48 , pp. 285-296
    • Bergeron, M.1    Gidday, J.M.2    Yu, A.Y.3    Semenza, G.L.4    Ferriero, D.M.5    Sharp, F.R.6
  • 10
    • 0033435198 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain
    • Bergeron M., Yu A.Y., Solway K.E., Semenza G.L., and Sharp F.R. Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur. J. Neurosci. 11 (1999) 4159-4170
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 4159-4170
    • Bergeron, M.1    Yu, A.Y.2    Solway, K.E.3    Semenza, G.L.4    Sharp, F.R.5
  • 11
    • 0032815188 scopus 로고    scopus 로고
    • Increased nitric oxide synthesis is not involved in delayed cerebral energy failure following focal hypoxic-ischemic injury to the developing brain
    • Blumberg R.M., Taylor D.L., Yue X., Aguan K., Mckenzie J., Cady E.B., Weiner C.P., Mehmet H., and Edwards A.D. Increased nitric oxide synthesis is not involved in delayed cerebral energy failure following focal hypoxic-ischemic injury to the developing brain. Pediatr. Res. 46 2 (1999) 224-231
    • (1999) Pediatr. Res. , vol.46 , Issue.2 , pp. 224-231
    • Blumberg, R.M.1    Taylor, D.L.2    Yue, X.3    Aguan, K.4    Mckenzie, J.5    Cady, E.B.6    Weiner, C.P.7    Mehmet, H.8    Edwards, A.D.9
  • 13
    • 0034255036 scopus 로고    scopus 로고
    • Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
    • Bruick R.K. Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc. Natl. Acad. Sci. U. S. A. 97 16 (2000) 9082-9087
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , Issue.16 , pp. 9082-9087
    • Bruick, R.K.1
  • 14
    • 33748444603 scopus 로고    scopus 로고
    • Oxygen treatment after experimental hypoxia-ischemia in neonatal rats alters the expression of HIF-1alpha and its downstream target genes
    • Calvert J.W., Cahill J., Yamaguchi-Okada M., and Zhang J.H. Oxygen treatment after experimental hypoxia-ischemia in neonatal rats alters the expression of HIF-1alpha and its downstream target genes. J. Appl. Physiol. 101 (2006) 853-865
    • (2006) J. Appl. Physiol. , vol.101 , pp. 853-865
    • Calvert, J.W.1    Cahill, J.2    Yamaguchi-Okada, M.3    Zhang, J.H.4
  • 15
    • 0142149237 scopus 로고    scopus 로고
    • Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model
    • Calvert J.W., Zhou C., Nanda A., and Zhang J.H. Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model. J. Appl. Physiol. 95 (2003) 2072-2080
    • (2003) J. Appl. Physiol. , vol.95 , pp. 2072-2080
    • Calvert, J.W.1    Zhou, C.2    Nanda, A.3    Zhang, J.H.4
  • 17
    • 0037109768 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1
    • Chavez J.C., and LaManna J.C. Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1. J. Neurosci. 22 (2002) 8922-8931
    • (2002) J. Neurosci. , vol.22 , pp. 8922-8931
    • Chavez, J.C.1    LaManna, J.C.2
  • 18
    • 49349109477 scopus 로고    scopus 로고
    • HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model
    • Chen W., Jadhav V., Tang J., and Zhang J.H. HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model. Neurobiol. Dis. 31 3 (2008) 433-441
    • (2008) Neurobiol. Dis. , vol.31 , Issue.3 , pp. 433-441
    • Chen, W.1    Jadhav, V.2    Tang, J.3    Zhang, J.H.4
  • 19
    • 26444561886 scopus 로고    scopus 로고
    • Neuroprotective effect of simvastatin in stroke: a comparison between adult and neonatal rat models of cerebral ischemia
    • Cimino M., Balduini W., Carloni S., Gelosa P., Guerrini U., Tremoli E., and Sironi L. Neuroprotective effect of simvastatin in stroke: a comparison between adult and neonatal rat models of cerebral ischemia. Neurotoxicology 26 (2005) 929-933
    • (2005) Neurotoxicology , vol.26 , pp. 929-933
    • Cimino, M.1    Balduini, W.2    Carloni, S.3    Gelosa, P.4    Guerrini, U.5    Tremoli, E.6    Sironi, L.7
  • 22
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • Digicaylioglu M., and Lipton S.A. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature 412 (2001) 641-647
    • (2001) Nature , vol.412 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 25
    • 59749089249 scopus 로고    scopus 로고
    • Fathali N., Lekic T., Jadhav J., Tang J., and Zhang J.H., 2007. Cyclooxygenase-2 inhibition attenuates hypoxic-ischemic brain injury in neonates. Neuroscience Meeting Planner San Diego, CA: Society for Neuroscience, Abstract#380 12/Z24 Online.
    • Fathali N., Lekic T., Jadhav J., Tang J., and Zhang J.H., 2007. Cyclooxygenase-2 inhibition attenuates hypoxic-ischemic brain injury in neonates. Neuroscience Meeting Planner San Diego, CA: Society for Neuroscience, Abstract#380 12/Z24 Online.
  • 26
    • 27244450463 scopus 로고    scopus 로고
    • Protecting neurons
    • Ferriero D.M. Protecting neurons. Epilepsia 46 Suppl 7 (2005) 45-51
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 7 , pp. 45-51
    • Ferriero, D.M.1
  • 28
    • 34250169470 scopus 로고    scopus 로고
    • The roles of aquaporin-4 in brain edema following neonatal hypoxia ischemia and reoxygenation in a cultured rat astrocyte model
    • Fu X., Li Q., Feng Z., and Mu D. The roles of aquaporin-4 in brain edema following neonatal hypoxia ischemia and reoxygenation in a cultured rat astrocyte model. Glia 55 9 (2007) 935-941
    • (2007) Glia , vol.55 , Issue.9 , pp. 935-941
    • Fu, X.1    Li, Q.2    Feng, Z.3    Mu, D.4
  • 30
    • 7544227524 scopus 로고    scopus 로고
    • Maternal hypoxia during pregnancy delays the development of motor reflexes in newborn mice
    • Golan H., Kashtutsky I., Hallak M., Sorokin Y., and Huleihel M. Maternal hypoxia during pregnancy delays the development of motor reflexes in newborn mice. Dev. Neurosci. 26 (2004) 24-29
    • (2004) Dev. Neurosci. , vol.26 , pp. 24-29
    • Golan, H.1    Kashtutsky, I.2    Hallak, M.3    Sorokin, Y.4    Huleihel, M.5
  • 31
    • 8444230560 scopus 로고    scopus 로고
    • Maternal hypoxia during pregnancy induces fetal neurodevelopmental brain damage: partial protection by magnesium sulfate
    • Golan H., Kashtuzki I., Hallak M., Sorokin Y., and Huleihel M. Maternal hypoxia during pregnancy induces fetal neurodevelopmental brain damage: partial protection by magnesium sulfate. J. Neurosci. Res. 78 (2004) 430-441
    • (2004) J. Neurosci. Res. , vol.78 , pp. 430-441
    • Golan, H.1    Kashtuzki, I.2    Hallak, M.3    Sorokin, Y.4    Huleihel, M.5
  • 32
    • 0035816732 scopus 로고    scopus 로고
    • Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: role of the p22(phox)-containing NADPH oxidase
    • Gorlach A., Diebold I., Schini-Kerth V.B., Berchner-Pfannschmidt U., Roth U., Brandes R.P., Kie0tzmann T., and Busse R. Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: role of the p22(phox)-containing NADPH oxidase. Circ. Res. 89 (2001) 47-54
    • (2001) Circ. Res. , vol.89 , pp. 47-54
    • Gorlach, A.1    Diebold, I.2    Schini-Kerth, V.B.3    Berchner-Pfannschmidt, U.4    Roth, U.5    Brandes, R.P.6    Kie0tzmann, T.7    Busse, R.8
  • 33
    • 12344282573 scopus 로고    scopus 로고
    • Interaction between endothelial heme oxygenase-2 and endothelin-1 in altered aortic reactivity after hypoxia in rats
    • Govindaraju V., Teoh H., Hamid Q., Cernacek P., and Ward M.E. Interaction between endothelial heme oxygenase-2 and endothelin-1 in altered aortic reactivity after hypoxia in rats. Am. J. Physiol, Heart Circ. Physiol. 288 (2005) H962-H970
    • (2005) Am. J. Physiol, Heart Circ. Physiol. , vol.288
    • Govindaraju, V.1    Teoh, H.2    Hamid, Q.3    Cernacek, P.4    Ward, M.E.5
  • 35
    • 0032588585 scopus 로고    scopus 로고
    • HIF-1alpha and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia
    • Halterman M.W., and Federoff H.J. HIF-1alpha and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia. Exp. Neurol. 159 (1999) 65-72
    • (1999) Exp. Neurol. , vol.159 , pp. 65-72
    • Halterman, M.W.1    Federoff, H.J.2
  • 36
    • 0033566792 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53
    • Halterman M.W., Miller C.C., and Federoff H.J. Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53. J. Neurosci. 19 (1999) 6818-6824
    • (1999) J. Neurosci. , vol.19 , pp. 6818-6824
    • Halterman, M.W.1    Miller, C.C.2    Federoff, H.J.3
  • 37
    • 17044417644 scopus 로고    scopus 로고
    • A role for hypoxia-inducible factor-1alpha in desferoxamine neuroprotection
    • 6
    • Hamrick S.E., McQuillen P.S., Jiang X., Mu D., Madan A., and Ferriero D.M. A role for hypoxia-inducible factor-1alpha in desferoxamine neuroprotection. Neurosci. Lett. 379 2 (2005) 96-100 6
    • (2005) Neurosci. Lett. , vol.379 , Issue.2 , pp. 96-100
    • Hamrick, S.E.1    McQuillen, P.S.2    Jiang, X.3    Mu, D.4    Madan, A.5    Ferriero, D.M.6
  • 39
    • 0346881343 scopus 로고    scopus 로고
    • Thrombin preconditioning attenuates brain edema induced by erythrocytes and iron
    • Hua Y., Keep R.F., Hoff J.T., and Xi G. Thrombin preconditioning attenuates brain edema induced by erythrocytes and iron. J. Cereb. Blood Flow Metab. 23 (2003) 1448-1454
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 1448-1454
    • Hua, Y.1    Keep, R.F.2    Hoff, J.T.3    Xi, G.4
  • 40
    • 0029753008 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
    • Huang L.E., Arany Z., Livingston D.M., and Bunn H.F. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J. Biol. Chem. 271 (1996) 32253-32259
    • (1996) J. Biol. Chem. , vol.271 , pp. 32253-32259
    • Huang, L.E.1    Arany, Z.2    Livingston, D.M.3    Bunn, H.F.4
  • 41
    • 2942670728 scopus 로고    scopus 로고
    • Angiogenesis and its regulatory factors in brain tissue of neonatal rat hypoxic-ischemic encephalopathy
    • Huang Y.F., Zhuang S.Q., Chen D.P., Liang Y.J., and Li X.Y. Angiogenesis and its regulatory factors in brain tissue of neonatal rat hypoxic-ischemic encephalopathy. Zhonghua Er Ke Za Zhi 42 (2004) 210-214
    • (2004) Zhonghua Er Ke Za Zhi , vol.42 , pp. 210-214
    • Huang, Y.F.1    Zhuang, S.Q.2    Chen, D.P.3    Liang, Y.J.4    Li, X.Y.5
  • 42
    • 0034131137 scopus 로고    scopus 로고
    • Immature brain injury via peroxynitrite production induced by inducible nitric oxide synthase after hypoxia-ischemia in rats
    • Ikeno S., Nagata N., Yoshida S., Takahashi H., Kigawa J., and Terakawa N. Immature brain injury via peroxynitrite production induced by inducible nitric oxide synthase after hypoxia-ischemia in rats. J. Obstet. Gynaecol. Res. 26 (2000) 227-234
    • (2000) J. Obstet. Gynaecol. Res. , vol.26 , pp. 227-234
    • Ikeno, S.1    Nagata, N.2    Yoshida, S.3    Takahashi, H.4    Kigawa, J.5    Terakawa, N.6
  • 45
    • 0034809282 scopus 로고    scopus 로고
    • Correlation of HO-1 expression with onset and reversal of hypoxia-induced vasoconstrictor hyporeactivity
    • Jernigan N.L., O'Donaughy T.L., and Walker B.R. Correlation of HO-1 expression with onset and reversal of hypoxia-induced vasoconstrictor hyporeactivity. Am. J. Physiol, Heart Circ. Physiol. 281 (2001) H298-H307
    • (2001) Am. J. Physiol, Heart Circ. Physiol. , vol.281
    • Jernigan, N.L.1    O'Donaughy, T.L.2    Walker, B.R.3
  • 46
    • 0029859510 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension
    • Jiang B.H., Semenza G.L., Bauer C., and Marti H.H. Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. Am. J. Physiol. 271 (1996) C1172-C1180
    • (1996) Am. J. Physiol. , vol.271
    • Jiang, B.H.1    Semenza, G.L.2    Bauer, C.3    Marti, H.H.4
  • 48
    • 0034675037 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain
    • Jin K.L., Mao X.O., Nagayama T., Goldsmith P.C., and Greenberg D.A. Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain. Neuroscience 99 (2000) 577-585
    • (2000) Neuroscience , vol.99 , pp. 577-585
    • Jin, K.L.1    Mao, X.O.2    Nagayama, T.3    Goldsmith, P.C.4    Greenberg, D.A.5
  • 49
    • 34548301779 scopus 로고    scopus 로고
    • Mast cell stabilization limits hypoxic-ischemic brain damage in the immature rat
    • Jin Y., Silverman A.J., and Vannucci S.J. Mast cell stabilization limits hypoxic-ischemic brain damage in the immature rat. Dev. Neurosci. 29 (2007) 373-384
    • (2007) Dev. Neurosci. , vol.29 , pp. 373-384
    • Jin, Y.1    Silverman, A.J.2    Vannucci, S.J.3
  • 50
    • 33749318557 scopus 로고    scopus 로고
    • Novel thioredoxin inhibitors paradoxically increase hypoxia-inducible factor-alpha expression but decrease functional transcriptional activity, DNA binding, and degradation
    • Jones D.T., Pugh C.W., Wigfield S., Stevens M.F., and Harris A.L. Novel thioredoxin inhibitors paradoxically increase hypoxia-inducible factor-alpha expression but decrease functional transcriptional activity, DNA binding, and degradation. Clin. Cancer Res. 12 (2006) 5384-5394
    • (2006) Clin. Cancer Res. , vol.12 , pp. 5384-5394
    • Jones, D.T.1    Pugh, C.W.2    Wigfield, S.3    Stevens, M.F.4    Harris, A.L.5
  • 51
    • 0034840276 scopus 로고    scopus 로고
    • Hypoxic preconditioning induces changes in HIF-1 target genes in neonatal rat brain
    • Jones N.M., and Bergeron M. Hypoxic preconditioning induces changes in HIF-1 target genes in neonatal rat brain. J. Cereb. Blood Flow Metab. 21 (2001) 1105-1114
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 1105-1114
    • Jones, N.M.1    Bergeron, M.2
  • 52
    • 20444430874 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1alpha using PX-478
    • Jordan B.F., Runquist M., Raghunand N., Baker A., Williams R., Kirkpatrick L., Powis G., and Gillies R.J. Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1alpha using PX-478. Neoplasia 7 (2005) 475-485
    • (2005) Neoplasia , vol.7 , pp. 475-485
    • Jordan, B.F.1    Runquist, M.2    Raghunand, N.3    Baker, A.4    Williams, R.5    Kirkpatrick, L.6    Powis, G.7    Gillies, R.J.8
  • 54
    • 1642453685 scopus 로고    scopus 로고
    • Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling
    • Kasuno K., Takabuchi S., Fukuda K., Kizaka-Kondoh S., Yodoi J., Adachi T., Semenza G.L., and Hirota K. Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling. J. Biol. Chem. 279 (2004) 2550-2558
    • (2004) J. Biol. Chem. , vol.279 , pp. 2550-2558
    • Kasuno, K.1    Takabuchi, S.2    Fukuda, K.3    Kizaka-Kondoh, S.4    Yodoi, J.5    Adachi, T.6    Semenza, G.L.7    Hirota, K.8
  • 55
    • 33746388438 scopus 로고    scopus 로고
    • Hypoxic damage to the periventricular white matter in neonatal brain: role of vascular endothelial growth factor, nitric oxide and excitotoxicity
    • Kaur C., Sivakumar V., Ang L.S., and Sundaresan A. Hypoxic damage to the periventricular white matter in neonatal brain: role of vascular endothelial growth factor, nitric oxide and excitotoxicity. J. Neurochem. 98 (2006) 1200-1216
    • (2006) J. Neurochem. , vol.98 , pp. 1200-1216
    • Kaur, C.1    Sivakumar, V.2    Ang, L.S.3    Sundaresan, A.4
  • 56
    • 51249118951 scopus 로고    scopus 로고
    • Melatonin attenuates hypoxia-induced ultrastructural changes and increased vascular permeability in the developing hippocampus
    • Kaur C., Sivakumar V., Lu J., Tang F.R., and Ling E.A. Melatonin attenuates hypoxia-induced ultrastructural changes and increased vascular permeability in the developing hippocampus. Brain Pathol. 18 4 (2008) 533-547
    • (2008) Brain Pathol. , vol.18 , Issue.4 , pp. 533-547
    • Kaur, C.1    Sivakumar, V.2    Lu, J.3    Tang, F.R.4    Ling, E.A.5
  • 57
    • 49349096194 scopus 로고    scopus 로고
    • Increase in dopaminergic neurons from mouse embryonic stem cell-derived neural progenitor/stem cells is mediated by hypoxia inducible factor-1alpha
    • Kim T.S., Misumi S., Jung C.G., Masuda T., Isobe Y., Furuyama F., Nishino H., and Hida H. Increase in dopaminergic neurons from mouse embryonic stem cell-derived neural progenitor/stem cells is mediated by hypoxia inducible factor-1alpha. J. Neurosci. Res. 86 11 (2008) 2353-2362
    • (2008) J. Neurosci. Res. , vol.86 , Issue.11 , pp. 2353-2362
    • Kim, T.S.1    Misumi, S.2    Jung, C.G.3    Masuda, T.4    Isobe, Y.5    Furuyama, F.6    Nishino, H.7    Hida, H.8
  • 59
    • 33847180453 scopus 로고    scopus 로고
    • Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species
    • Kunz A., Anrather J., Zhou P., Orio M., and Iadecola C. Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species. J. Cereb. Blood Flow Metab. 27 (2007) 545-551
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 545-551
    • Kunz, A.1    Anrather, J.2    Zhou, P.3    Orio, M.4    Iadecola, C.5
  • 60
    • 33646672428 scopus 로고    scopus 로고
    • Acute hypoxia-ischemia results in hydrogen peroxide accumulation in neonatal but not adult mouse brain
    • Lafemina M.J., Sheldon R.A., and Ferriero D.M. Acute hypoxia-ischemia results in hydrogen peroxide accumulation in neonatal but not adult mouse brain. Pediatr. Res. 59 (2006) 680-683
    • (2006) Pediatr. Res. , vol.59 , pp. 680-683
    • Lafemina, M.J.1    Sheldon, R.A.2    Ferriero, D.M.3
  • 61
    • 0037409986 scopus 로고    scopus 로고
    • Chronic hypoxia in development selectively alters the activities of key enzymes of glucose oxidative metabolism in brain regions
    • Lai J.C., White B.K., Buerstatte C.R., Haddad G.G., Novotny Jr. E.J., and Behar K.L. Chronic hypoxia in development selectively alters the activities of key enzymes of glucose oxidative metabolism in brain regions. Neurochem. Res. 28 6 (2003) 933-940
    • (2003) Neurochem. Res. , vol.28 , Issue.6 , pp. 933-940
    • Lai, J.C.1    White, B.K.2    Buerstatte, C.R.3    Haddad, G.G.4    Novotny Jr., E.J.5    Behar, K.L.6
  • 62
    • 39149103381 scopus 로고    scopus 로고
    • The involvement of phosphoinositid 3-kinase/Akt pathway in the activation of hypoxia-inducible factor-1alpha in the developing rat brain after hypoxia-ischemia
    • Mar 4
    • Li L., Qu Y., Mao M., Xiong Y., and Mu D. The involvement of phosphoinositid 3-kinase/Akt pathway in the activation of hypoxia-inducible factor-1alpha in the developing rat brain after hypoxia-ischemia. Brain Res. 1197 (2008) 152-158 Mar 4
    • (2008) Brain Res. , vol.1197 , pp. 152-158
    • Li, L.1    Qu, Y.2    Mao, M.3    Xiong, Y.4    Mu, D.5
  • 63
    • 39749187384 scopus 로고    scopus 로고
    • The requirement of extracellular signal-related protein kinase pathway in the activation of hypoxia inducible factor 1alpha in the developing rat brain after hypoxia-ischemia
    • Li L., Xiong Y., Qu Y., Mao M., Mu W., Wang H., and Mu D. The requirement of extracellular signal-related protein kinase pathway in the activation of hypoxia inducible factor 1alpha in the developing rat brain after hypoxia-ischemia. Acta Neuropathol. 115 3 (2008) 297-303
    • (2008) Acta Neuropathol. , vol.115 , Issue.3 , pp. 297-303
    • Li, L.1    Xiong, Y.2    Qu, Y.3    Mao, M.4    Mu, W.5    Wang, H.6    Mu, D.7
  • 64
    • 10044264403 scopus 로고    scopus 로고
    • Multiple effects of hyperbaric oxygen on the expression of HIF-1 alpha and apoptotic genes in a global ischemia-hypotension rat model
    • Li Y., Zhou C., Calvert J.W., Colohan A.R., and Zhang J.H. Multiple effects of hyperbaric oxygen on the expression of HIF-1 alpha and apoptotic genes in a global ischemia-hypotension rat model. Exp. Neurol. 191 (2005) 198-210
    • (2005) Exp. Neurol. , vol.191 , pp. 198-210
    • Li, Y.1    Zhou, C.2    Calvert, J.W.3    Colohan, A.R.4    Zhang, J.H.5
  • 65
    • 0037041012 scopus 로고    scopus 로고
    • Identification and functional analysis of the rat caspase-3 gene promoter
    • Liu W., Wang G., and Yakovlev A.G. Identification and functional analysis of the rat caspase-3 gene promoter. J. Biol. Chem. 277 (2002) 8273-8278
    • (2002) J. Biol. Chem. , vol.277 , pp. 8273-8278
    • Liu, W.1    Wang, G.2    Yakovlev, A.G.3
  • 66
    • 37549028456 scopus 로고    scopus 로고
    • Calcineurin promotes hypoxia-inducible factor 1{alpha} expression by dephosphorylating RACK1 and blocking RACK1 dimerization
    • Liu Y.V., Hubbi M.E., Pan F., McDonald K.R., Mansharamani M., Cole R.N., Liu J.O., and Semenza G.L. Calcineurin promotes hypoxia-inducible factor 1{alpha} expression by dephosphorylating RACK1 and blocking RACK1 dimerization. J. Biol. Chem. 282 (2007) 37064-37073
    • (2007) J. Biol. Chem. , vol.282 , pp. 37064-37073
    • Liu, Y.V.1    Hubbi, M.E.2    Pan, F.3    McDonald, K.R.4    Mansharamani, M.5    Cole, R.N.6    Liu, J.O.7    Semenza, G.L.8
  • 67
    • 10644287654 scopus 로고    scopus 로고
    • Nitric oxide, hypoxia and brain inflammation
    • Mander P., and Brown G.C. Nitric oxide, hypoxia and brain inflammation. Biochem. Soc. Trans. 32 (2004) 1068-1069
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 1068-1069
    • Mander, P.1    Brown, G.C.2
  • 68
    • 33746210833 scopus 로고    scopus 로고
    • Intrahippocampal injection of endothelin-1 in immature rats results in neuronal death, development of epilepsy and behavioral abnormalities later in life
    • Mateffyova A., Otahal J., Tsenov G., Mares P., and Kubova H. Intrahippocampal injection of endothelin-1 in immature rats results in neuronal death, development of epilepsy and behavioral abnormalities later in life. Eur. J. Neurosci. 24 (2006) 351-360
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 351-360
    • Mateffyova, A.1    Otahal, J.2    Tsenov, G.3    Mares, P.4    Kubova, H.5
  • 69
    • 3142746742 scopus 로고    scopus 로고
    • HIF-1alpha reveals a binding activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion
    • Matrone C., Pignataro G., Molinaro P., Irace C., Scorziello A., Di Renzo G.F., and Annunziato L. HIF-1alpha reveals a binding activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion. J. Neurochem. 90 (2004) 368-378
    • (2004) J. Neurochem. , vol.90 , pp. 368-378
    • Matrone, C.1    Pignataro, G.2    Molinaro, P.3    Irace, C.4    Scorziello, A.5    Di Renzo, G.F.6    Annunziato, L.7
  • 70
    • 0030583097 scopus 로고    scopus 로고
    • Microglia-astrocyte interactions after cortisone treatment in a neonatal hypoxia-ischemia model
    • McRae A., Bona E., and Hagberg H. Microglia-astrocyte interactions after cortisone treatment in a neonatal hypoxia-ischemia model. Brain Res. Dev. Brain Res. 94 (1996) 44-51
    • (1996) Brain Res. Dev. Brain Res. , vol.94 , pp. 44-51
    • McRae, A.1    Bona, E.2    Hagberg, H.3
  • 71
    • 40549139758 scopus 로고    scopus 로고
    • Synergystic induction of HIF-1alpha transcriptional activity by hypoxia and lipopolysaccharide in macrophages
    • Mi Z., Rapisarda A., Taylor L., Brooks A., Creighton-Gutteridge M., Melillo G., and Varesio L. Synergystic induction of HIF-1alpha transcriptional activity by hypoxia and lipopolysaccharide in macrophages. Cell Cycle 15 (2008) 232-241
    • (2008) Cell Cycle , vol.15 , pp. 232-241
    • Mi, Z.1    Rapisarda, A.2    Taylor, L.3    Brooks, A.4    Creighton-Gutteridge, M.5    Melillo, G.6    Varesio, L.7
  • 72
    • 33847300431 scopus 로고    scopus 로고
    • Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures
    • Montero M., Poulsen F.R., Noraberg J., Kirkeby A., van Beek J., Leist M., and Zimmer J. Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures. Exp. Neurol. 204 (2007) 106-117
    • (2007) Exp. Neurol. , vol.204 , pp. 106-117
    • Montero, M.1    Poulsen, F.R.2    Noraberg, J.3    Kirkeby, A.4    van Beek, J.5    Leist, M.6    Zimmer, J.7
  • 73
    • 0347479363 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model
    • Mu D., Jiang X., Sheldon R.A., Fox C.K., Hamrick S.E., Vexler Z.S., and Ferriero D.M. Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model. Neurobiol. Dis. 14 (2003) 524-534
    • (2003) Neurobiol. Dis. , vol.14 , pp. 524-534
    • Mu, D.1    Jiang, X.2    Sheldon, R.A.3    Fox, C.K.4    Hamrick, S.E.5    Vexler, Z.S.6    Ferriero, D.M.7
  • 74
    • 24744444711 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha and erythropoietin upregulation with deferoxamine salvage after neonatal stroke
    • Mu D., Chang Y.S., Vexler Z.S., and Ferriero D.M. Hypoxia-inducible factor 1alpha and erythropoietin upregulation with deferoxamine salvage after neonatal stroke. Exp. Neurol. 195 (2005) 407-415
    • (2005) Exp. Neurol. , vol.195 , pp. 407-415
    • Mu, D.1    Chang, Y.S.2    Vexler, Z.S.3    Ferriero, D.M.4
  • 75
    • 0030665117 scopus 로고    scopus 로고
    • Vulnerability to cerebral hypoxic-ischemic insult in neonatal but not in adult rats is in parallel with disruption of the blood-brain barrier
    • Muramatsu K., Fukuda A., Togari H., Wada Y., and Nishino H. Vulnerability to cerebral hypoxic-ischemic insult in neonatal but not in adult rats is in parallel with disruption of the blood-brain barrier. Stroke 28 (1997) 2281-2288
    • (1997) Stroke , vol.28 , pp. 2281-2288
    • Muramatsu, K.1    Fukuda, A.2    Togari, H.3    Wada, Y.4    Nishino, H.5
  • 77
    • 14344264703 scopus 로고    scopus 로고
    • Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics - an update
    • Neckers L., and Neckers K. Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics - an update. Expert Opin. Emerg. Drugs 10 (2005) 137-149
    • (2005) Expert Opin. Emerg. Drugs , vol.10 , pp. 137-149
    • Neckers, L.1    Neckers, K.2
  • 78
    • 0035890467 scopus 로고    scopus 로고
    • cDNA cloning and promoter analysis of rat caspase-9
    • Nishiyama J., Yi X., Venkatachalam M.A., and Dong Z. cDNA cloning and promoter analysis of rat caspase-9. Biochem. J. 360 (2001) 49-56
    • (2001) Biochem. J. , vol.360 , pp. 49-56
    • Nishiyama, J.1    Yi, X.2    Venkatachalam, M.A.3    Dong, Z.4
  • 79
    • 33751002345 scopus 로고    scopus 로고
    • Intervention strategies for neonatal hypoxic-ischemic cerebral injury
    • Perlman J.M. Intervention strategies for neonatal hypoxic-ischemic cerebral injury. Clin. Ther. 28 (2006) 1353-1365
    • (2006) Clin. Ther. , vol.28 , pp. 1353-1365
    • Perlman, J.M.1
  • 81
    • 0042853130 scopus 로고    scopus 로고
    • Networking neonatal units
    • Renton M. Networking neonatal units. Pract. Midwife 6 (2003) 4-5
    • (2003) Pract. Midwife , vol.6 , pp. 4-5
    • Renton, M.1
  • 82
    • 36749014049 scopus 로고    scopus 로고
    • Developmental regulation of hypoxia-inducible factor 1 and prolyl-hydroxylases in pulmonary vascular smooth muscle cells
    • Resnik E.R., Herron J.M., Lyu S.C., and Cornfield D.N. Developmental regulation of hypoxia-inducible factor 1 and prolyl-hydroxylases in pulmonary vascular smooth muscle cells. Proc. Natl. Acad. Sci. U. S. A. 104 47 (2007) 18789-18794
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , Issue.47 , pp. 18789-18794
    • Resnik, E.R.1    Herron, J.M.2    Lyu, S.C.3    Cornfield, D.N.4
  • 83
    • 0032725554 scopus 로고    scopus 로고
    • p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1
    • Richard D.E., Berra E., Gothie E., Roux D., and Pouyssegur J. p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. J. Biol. Chem. 274 (1999) 32631-32637
    • (1999) J. Biol. Chem. , vol.274 , pp. 32631-32637
    • Richard, D.E.1    Berra, E.2    Gothie, E.3    Roux, D.4    Pouyssegur, J.5
  • 84
    • 11144239579 scopus 로고    scopus 로고
    • 2-methoxyestradiol inhibits hypoxia-inducible factor 1alpha, tumor growth, and angiogenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma
    • Ricker J.L., Chen Z., Yang X.P., Pribluda V.S., Swartz G.M., and Van Waes C. 2-methoxyestradiol inhibits hypoxia-inducible factor 1alpha, tumor growth, and angiogenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma. Clin. Cancer Res. 10 (2004) 8665-8673
    • (2004) Clin. Cancer Res. , vol.10 , pp. 8665-8673
    • Ricker, J.L.1    Chen, Z.2    Yang, X.P.3    Pribluda, V.S.4    Swartz, G.M.5    Van Waes, C.6
  • 86
    • 0033975258 scopus 로고    scopus 로고
    • Effects of gestational hypoxia on mRNA levels of Glut3 and Glut4 transporters, hypoxia inducible factor-1 and thyroid hormone receptors in developing rat brain
    • Royer C., Lachuer J., Crouzoulon G., Roux J., Peyronnet J., Mamet J., Pequignot J., and Dalmaz Y. Effects of gestational hypoxia on mRNA levels of Glut3 and Glut4 transporters, hypoxia inducible factor-1 and thyroid hormone receptors in developing rat brain. Brain Res. 856 1-2 (2000) 119-128
    • (2000) Brain Res. , vol.856 , Issue.1-2 , pp. 119-128
    • Royer, C.1    Lachuer, J.2    Crouzoulon, G.3    Roux, J.4    Peyronnet, J.5    Mamet, J.6    Pequignot, J.7    Dalmaz, Y.8
  • 87
    • 33845225602 scopus 로고    scopus 로고
    • Glucocorticoids exacerbate hypoxia-induced expression of the pro-apoptotic gene Bnip3 in the developing cortex
    • Sandau U.S., and Handa R.J. Glucocorticoids exacerbate hypoxia-induced expression of the pro-apoptotic gene Bnip3 in the developing cortex. Neuroscience 144 (2007) 482-494
    • (2007) Neuroscience , vol.144 , pp. 482-494
    • Sandau, U.S.1    Handa, R.J.2
  • 88
    • 1242314873 scopus 로고    scopus 로고
    • Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus
    • Schmidt-Kastner R., Aguirre-Chen C., Kietzmann T., Saul I., Busto R., and Ginsberg M.D. Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus. Brain Res. 1001 (2004) 133-142
    • (2004) Brain Res. , vol.1001 , pp. 133-142
    • Schmidt-Kastner, R.1    Aguirre-Chen, C.2    Kietzmann, T.3    Saul, I.4    Busto, R.5    Ginsberg, M.D.6
  • 91
    • 38849175410 scopus 로고    scopus 로고
    • Genetic and pharmacologic manipulation of oxidative stress after neonatal hypoxia-ischemia
    • Sheldon R.A., Christen S., and Ferriero D.M. Genetic and pharmacologic manipulation of oxidative stress after neonatal hypoxia-ischemia. Int. J. Dev. Neurosci. 26 1 (2008) 87-92
    • (2008) Int. J. Dev. Neurosci. , vol.26 , Issue.1 , pp. 87-92
    • Sheldon, R.A.1    Christen, S.2    Ferriero, D.M.3
  • 92
    • 40549121252 scopus 로고    scopus 로고
    • Cobalt supplementation promotes hypoxic tolerance and facilitates acclimatization to hypobaric hypoxia in rat brain
    • Shrivastava K., Ram M.S., Bansal A., Singh S.S., and Ilavazhagan G. Cobalt supplementation promotes hypoxic tolerance and facilitates acclimatization to hypobaric hypoxia in rat brain. High Alt. Med. Biol. 9 1 (2008) 63-75
    • (2008) High Alt. Med. Biol. , vol.9 , Issue.1 , pp. 63-75
    • Shrivastava, K.1    Ram, M.S.2    Bansal, A.3    Singh, S.S.4    Ilavazhagan, G.5
  • 94
    • 0035884701 scopus 로고    scopus 로고
    • Sowter H.M., Ratcliffe P.J., Watson P., Greenberg A.H., Harris A.L. 2001. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. 15;61(18):6669-73.
    • Sowter H.M., Ratcliffe P.J., Watson P., Greenberg A.H., Harris A.L. 2001. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. 15;61(18):6669-73.
  • 96
    • 0028316784 scopus 로고
    • Early ultrastructural changes in blood-brain barrier vessels of the rat embryo
    • Stewart P.A., and Hayakawa K. Early ultrastructural changes in blood-brain barrier vessels of the rat embryo. Brain Res. Dev. Brain Res. 78 (1994) 25-34
    • (1994) Brain Res. Dev. Brain Res. , vol.78 , pp. 25-34
    • Stewart, P.A.1    Hayakawa, K.2
  • 97
    • 0037183765 scopus 로고    scopus 로고
    • Concurrent formation of peroxynitrite with the expression of inducible nitric oxide synthase in the brain during middle cerebral artery occlusion and reperfusion in rats
    • Suzuki M., Tabuchi M., Ikeda M., and Tomita T. Concurrent formation of peroxynitrite with the expression of inducible nitric oxide synthase in the brain during middle cerebral artery occlusion and reperfusion in rats. Brain Res. 951 (2002) 113-120
    • (2002) Brain Res. , vol.951 , pp. 113-120
    • Suzuki, M.1    Tabuchi, M.2    Ikeda, M.3    Tomita, T.4
  • 98
    • 40049108004 scopus 로고    scopus 로고
    • HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam
    • Trollmann R., Schneider J., Keller S., Strasser K., Wenzel D., Rascher W., Ogunshola O.O., and Gassmann M. HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam. Brain Res. 1199 (2008) 27-36
    • (2008) Brain Res. , vol.1199 , pp. 27-36
    • Trollmann, R.1    Schneider, J.2    Keller, S.3    Strasser, K.4    Wenzel, D.5    Rascher, W.6    Ogunshola, O.O.7    Gassmann, M.8
  • 99
    • 0035919751 scopus 로고    scopus 로고
    • Perinatal hypoxia/ischemia-induced endothelin-1 mRNA in astrocyte-like and endothelial cells
    • Tsang M.C., Lo A.C., Cheung P.T., Chung S.S., and Chung S.K. Perinatal hypoxia/ischemia-induced endothelin-1 mRNA in astrocyte-like and endothelial cells. Neuroreport 12 (2001) 2265-2270
    • (2001) Neuroreport , vol.12 , pp. 2265-2270
    • Tsang, M.C.1    Lo, A.C.2    Cheung, P.T.3    Chung, S.S.4    Chung, S.K.5
  • 100
    • 0033982825 scopus 로고    scopus 로고
    • Protective effect of aminoguanidine on hypoxic-ischemic brain damage and temporal profile of brain nitric oxide in neonatal rat
    • Tsuji M., Higuchi Y., Shiraishi K., Kume T., Akaike A., and Hattori H. Protective effect of aminoguanidine on hypoxic-ischemic brain damage and temporal profile of brain nitric oxide in neonatal rat. Pediatr. Res. 47 (2000) 79-83
    • (2000) Pediatr. Res. , vol.47 , pp. 79-83
    • Tsuji, M.1    Higuchi, Y.2    Shiraishi, K.3    Kume, T.4    Akaike, A.5    Hattori, H.6
  • 102
    • 24144502457 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase isoforms and nitrotyrosine formation after hypoxia-ischemia in the neonatal rat brain
    • van den Tweel E.R., Nijboer C., Kavelaars A., Heijnen C.J., Groenendaal F., and van Bel F. Expression of nitric oxide synthase isoforms and nitrotyrosine formation after hypoxia-ischemia in the neonatal rat brain. J. Neuroimmunol. 167 (2005) 64-71
    • (2005) J. Neuroimmunol. , vol.167 , pp. 64-71
    • van den Tweel, E.R.1    Nijboer, C.2    Kavelaars, A.3    Heijnen, C.J.4    Groenendaal, F.5    van Bel, F.6
  • 104
    • 39749188133 scopus 로고    scopus 로고
    • The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes
    • Vangeison G., Carr D., Federoff H.J., and Rempe D.A. The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes. J. Neurosci. 28 8 (2008) 1988-1993
    • (2008) J. Neurosci. , vol.28 , Issue.8 , pp. 1988-1993
    • Vangeison, G.1    Carr, D.2    Federoff, H.J.3    Rempe, D.A.4
  • 106
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang G.L., Jiang B.H., Rue E.A., and Semenza G.L. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 5510-5514
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 107
    • 0028785860 scopus 로고
    • Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1
    • Wang G.L., Jiang B.H., and Semenza G.L. Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1. Biochem. Biophys. Res. Commun. 216 (1995) 669-675
    • (1995) Biochem. Biophys. Res. Commun. , vol.216 , pp. 669-675
    • Wang, G.L.1    Jiang, B.H.2    Semenza, G.L.3
  • 108
    • 34548131624 scopus 로고    scopus 로고
    • Albumin reduces blood-brain barrier permeability but does not alter infarct size in a rat model of neonatal stroke
    • Wang R., Ashwal S., Tone B., Tian H.R., Badaut J., Rasmussen A., and Obenaus A. Albumin reduces blood-brain barrier permeability but does not alter infarct size in a rat model of neonatal stroke. Pediatr. Res. 62 (2007) 261-266
    • (2007) Pediatr. Res. , vol.62 , pp. 261-266
    • Wang, R.1    Ashwal, S.2    Tone, B.3    Tian, H.R.4    Badaut, J.5    Rasmussen, A.6    Obenaus, A.7
  • 110
    • 0030583293 scopus 로고    scopus 로고
    • In vivo expression of mRNAs encoding hypoxia-inducible factor 1
    • Wiener C.M., Booth G., and Semenza G.L. In vivo expression of mRNAs encoding hypoxia-inducible factor 1. Biochem. Biophys. Res. Commun. 225 (1996) 485-488
    • (1996) Biochem. Biophys. Res. Commun. , vol.225 , pp. 485-488
    • Wiener, C.M.1    Booth, G.2    Semenza, G.L.3
  • 111
    • 0034649507 scopus 로고    scopus 로고
    • Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
    • Wykoff C.C., Pugh C.W., Maxwell P.H., Harris A.L., and Ratcliffe P.J. Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling. Oncogene 19 (2000) 6297-6305
    • (2000) Oncogene , vol.19 , pp. 6297-6305
    • Wykoff, C.C.1    Pugh, C.W.2    Maxwell, P.H.3    Harris, A.L.4    Ratcliffe, P.J.5
  • 112
    • 0033206862 scopus 로고    scopus 로고
    • Study on the relationship between perinatal hypoxia and concentration of endothelin-1 in amniotic fluid
    • Xu L., Liu P., and Yan D. Study on the relationship between perinatal hypoxia and concentration of endothelin-1 in amniotic fluid. Zhonghua Fu Chan Ke Za Zhi 34 (1999) 591-593
    • (1999) Zhonghua Fu Chan Ke Za Zhi , vol.34 , pp. 591-593
    • Xu, L.1    Liu, P.2    Yan, D.3
  • 113
    • 17644415372 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase and cyclooxygenase-2 mRNA in brain damage induced by lipopolysaccharide and intermittent hypoxia-ischemia in neonatal rats
    • Yang L., Sameshima H., Yamaguchi M., and Ikenoue T. Expression of inducible nitric oxide synthase and cyclooxygenase-2 mRNA in brain damage induced by lipopolysaccharide and intermittent hypoxia-ischemia in neonatal rats. J. Obstet. Gynaecol. Res. 31 (2005) 185-191
    • (2005) J. Obstet. Gynaecol. Res. , vol.31 , pp. 185-191
    • Yang, L.1    Sameshima, H.2    Yamaguchi, M.3    Ikenoue, T.4
  • 115
    • 30744434357 scopus 로고    scopus 로고
    • TAT-mediated delivery of Bcl-xL protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF
    • Yin W., Cao G., Johnnides M.J., Signore A.P., Luo Y., Hickey R.W., and Chen J. TAT-mediated delivery of Bcl-xL protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF. Neurobiol. Dis. 21 (2006) 358-371
    • (2006) Neurobiol. Dis. , vol.21 , pp. 358-371
    • Yin, W.1    Cao, G.2    Johnnides, M.J.3    Signore, A.P.4    Luo, Y.5    Hickey, R.W.6    Chen, J.7
  • 116
    • 33947494524 scopus 로고    scopus 로고
    • Preconditioning suppresses inflammation in neonatal hypoxic ischemia via Akt activation
    • Yin W., Signore A.P., Iwai M., Cao G., Gao Y., Johnnides M.J., Hickey R.W., and Chen J. Preconditioning suppresses inflammation in neonatal hypoxic ischemia via Akt activation. Stroke 38 (2007) 1017-1024
    • (2007) Stroke , vol.38 , pp. 1017-1024
    • Yin, W.1    Signore, A.P.2    Iwai, M.3    Cao, G.4    Gao, Y.5    Johnnides, M.J.6    Hickey, R.W.7    Chen, J.8
  • 117
    • 0031753986 scopus 로고    scopus 로고
    • Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung
    • Yu A.Y., Frid M.G., Shimoda L.A., Wiener C.M., Stenmark K., and Semenza G.L. Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung. Am. J. Physiol. 275 (1998) L818-L826
    • (1998) Am. J. Physiol. , vol.275
    • Yu, A.Y.1    Frid, M.G.2    Shimoda, L.A.3    Wiener, C.M.4    Stenmark, K.5    Semenza, G.L.6
  • 118
    • 2942677080 scopus 로고    scopus 로고
    • Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-1
    • Zhang B., Tanaka J., Yang L., Yang L., Sakanaka M., Hata R., Maeda N., and Mitsuda N. Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-1. Neuroscience 126 (2004) 433-440
    • (2004) Neuroscience , vol.126 , pp. 433-440
    • Zhang, B.1    Tanaka, J.2    Yang, L.3    Yang, L.4    Sakanaka, M.5    Hata, R.6    Maeda, N.7    Mitsuda, N.8
  • 119
    • 41549120198 scopus 로고    scopus 로고
    • Hypoxia-driven proliferation of embryonic neural stem/progenitor cells-role of hypoxia-inducible transcription factor-1alpha
    • Zhao T., Zhang C.P., Liu Z.H., Wu L.Y., Huang X., Wu H.T., Xiong L., Wang X., Wang X.M., Zhu L.L., and Fan M. Hypoxia-driven proliferation of embryonic neural stem/progenitor cells-role of hypoxia-inducible transcription factor-1alpha. FEBS J. 275 8 (2008) 1824-1834
    • (2008) FEBS J. , vol.275 , Issue.8 , pp. 1824-1834
    • Zhao, T.1    Zhang, C.P.2    Liu, Z.H.3    Wu, L.Y.4    Huang, X.5    Wu, H.T.6    Xiong, L.7    Wang, X.8    Wang, X.M.9    Zhu, L.L.10    Fan, M.11
  • 121
    • 27644508232 scopus 로고    scopus 로고
    • Experimental study on the expression of HIF-1alpha and its relationship to apoptosis in tissues around cerebral bleeding loci
    • Zhu S., Tang Z., Guo S., Peng L., Fang S., and Zhang S. Experimental study on the expression of HIF-1alpha and its relationship to apoptosis in tissues around cerebral bleeding loci. J. Huazhong Univ. Sci. Technolog. Med. Sci. 24 (2004) 373-375
    • (2004) J. Huazhong Univ. Sci. Technolog. Med. Sci. , vol.24 , pp. 373-375
    • Zhu, S.1    Tang, Z.2    Guo, S.3    Peng, L.4    Fang, S.5    Zhang, S.6
  • 122
    • 38449121857 scopus 로고    scopus 로고
    • Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia
    • Ziello J.E., Jovin I.S., and Huang Y. Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia. Yale J. Biol. Med. 80 (2007) 51-60
    • (2007) Yale J. Biol. Med. , vol.80 , pp. 51-60
    • Ziello, J.E.1    Jovin, I.S.2    Huang, Y.3


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