Targeted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts

Cardiovascular Research

Volumn 55, Issue 3, 2002, Pages 672-680

  Saurin, Adrian T ^a   Pennington, Daniel J ^b   Raat, Nicolaas J H ^c   Latchman, David S ^d   Owen, Michael J ^b   Marber, Michael S ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Ischemia; Preconditioning; Protein kinases

Indexed keywords

BUFFER; ISOENZYME; PROTEIN KINASE C EPSILON; PROTEIN KINASE C;

ALLELE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE DISRUPTION; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANALYSIS OF VARIANCE; ANIMAL; COMPARATIVE STUDY; GENETICS; HEART CONTRACTION; HEART INFARCTION; HEART MUSCLE; METHODOLOGY; MOUSE MUTANT; PATHOLOGY; PERFUSION;

ANALYSIS OF VARIANCE; ANIMAL; COMPARATIVE STUDY; ISCHEMIC PRECONDITIONING, MYOCARDIAL; ISOENZYMES; MALE; MICE; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIUM; PERFUSION; PROTEIN KINASE C; SUPPORT, NON-U.S. GOV'T; ANIMALS;

EID: 0036023643     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00325-5     Document Type: Article

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