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Volumn 295, Issue 2, 2008, Pages

Early fetal hypoxia leads to growth restriction and myocardial thinning

Author keywords

Epicardium; Human intrauterine growth restriction; Hypoxia inducible transcription factor 1; Insulin like growth factor binding protein 1; Myocardium

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; FETOPROTEIN; OXYGEN;

EID: 51149120779     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00771.2007     Document Type: Article
Times cited : (142)

References (89)
  • 1
    • 0037119925 scopus 로고    scopus 로고
    • Deaths: Leading causes for 2000
    • Anderson RN. Deaths: leading causes for 2000. Natl Vital Stat Rep 50: 1-85, 2002.
    • (2002) Natl Vital Stat Rep , vol.50 , pp. 1-85
    • Anderson, R.N.1
  • 2
    • 0030807440 scopus 로고    scopus 로고
    • Effect of long-term cocaine administration to pregnant ewes on fetal hemodynamics, oxygenation, and growth
    • Arbeille P, Maulik D, Salihagic A, Locatelli A, Lansac J, Platt LD. Effect of long-term cocaine administration to pregnant ewes on fetal hemodynamics, oxygenation, and growth. Obstet Gynecol 90: 795-802, 1997.
    • (1997) Obstet Gynecol , vol.90 , pp. 795-802
    • Arbeille, P.1    Maulik, D.2    Salihagic, A.3    Locatelli, A.4    Lansac, J.5    Platt, L.D.6
  • 3
    • 0019378681 scopus 로고
    • Patterns of fetal lamb regional cerebral blood flow during and after prolonged hypoxia: Studies during the posthypoxic recovery period
    • Ashwal S, Majcher JS, Longo LD. Patterns of fetal lamb regional cerebral blood flow during and after prolonged hypoxia: studies during the posthypoxic recovery period. Am J Obstet Gynecol 139: 365-372, 1981.
    • (1981) Am J Obstet Gynecol , vol.139 , pp. 365-372
    • Ashwal, S.1    Majcher, J.S.2    Longo, L.D.3
  • 4
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker J, Liu JP, Robertson EJ, Efstratiadis A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75: 73-82, 1993.
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 6
    • 0030918435 scopus 로고    scopus 로고
    • The fetal origins of coronary heart disease
    • Barker DJ. The fetal origins of coronary heart disease. Eur Heart J 18: 883-884, 1997.
    • (1997) Eur Heart J , vol.18 , pp. 883-884
    • Barker, D.J.1
  • 7
    • 0024542325 scopus 로고
    • Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease
    • Barker DJ, Osmond C, Golding J, Kuh D, Wadsworth ME. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ 298: 564-567, 1989.
    • (1989) BMJ , vol.298 , pp. 564-567
    • Barker, D.J.1    Osmond, C.2    Golding, J.3    Kuh, D.4    Wadsworth, M.E.5
  • 8
    • 0038069367 scopus 로고    scopus 로고
    • Birth insult interacts with stress at adulthood to alter dopaminergic function in animal models: Possible implications for schizophrenia and other disorders
    • Boksa P, El-Khodor BF. Birth insult interacts with stress at adulthood to alter dopaminergic function in animal models: possible implications for schizophrenia and other disorders. Neurosci Biobehav Rev 27: 91-101, 2003.
    • (2003) Neurosci Biobehav Rev , vol.27 , pp. 91-101
    • Boksa, P.1    El-Khodor, B.F.2
  • 10
    • 0025011760 scopus 로고
    • Chronic fetal hypoxia and sudden infant death syndrome: Interaction between maternal smoking and low hematocrit during pregnancy
    • Bulterys MG, Greenland S, Kraus JF. Chronic fetal hypoxia and sudden infant death syndrome: interaction between maternal smoking and low hematocrit during pregnancy. Pediatrics 86: 535-540, 1990.
    • (1990) Pediatrics , vol.86 , pp. 535-540
    • Bulterys, M.G.1    Greenland, S.2    Kraus, J.F.3
  • 11
    • 34347267274 scopus 로고    scopus 로고
    • Effects of hypoxia on glucose, insulin, glucagon, and modulation by corticotropin-releasing factor receptor type 1 in the rat
    • Chen XQ, Dong J, Niu CY, Fan JM, Du JZ. Effects of hypoxia on glucose, insulin, glucagon, and modulation by corticotropin-releasing factor receptor type 1 in the rat. Endocrinology 148: 3271-3278, 2007.
    • (2007) Endocrinology , vol.148 , pp. 3271-3278
    • Chen, X.Q.1    Dong, J.2    Niu, C.Y.3    Fan, J.M.4    Du, J.Z.5
  • 12
    • 0013887745 scopus 로고
    • Abnormal development of the rat heart during prenatal hypoxic stress
    • Clemmer TP, Telford IR. Abnormal development of the rat heart during prenatal hypoxic stress. Proc Soc Exp Biol Med 121: 800-803, 1966.
    • (1966) Proc Soc Exp Biol Med , vol.121 , pp. 800-803
    • Clemmer, T.P.1    Telford, I.R.2
  • 14
  • 15
    • 0028916152 scopus 로고
    • Death before birth: Clues from gene knockouts and mutations
    • Copp AJ. Death before birth: clues from gene knockouts and mutations. Trends Genet 11: 87-93, 1995.
    • (1995) Trends Genet , vol.11 , pp. 87-93
    • Copp, A.J.1
  • 16
    • 0022979850 scopus 로고
    • Fetal growth retardation in rats from different levels of hypoxia
    • de Grauw TJ, Myers RE, Scott WJ. Fetal growth retardation in rats from different levels of hypoxia. Biol Neonate 49: 85-89, 1986.
    • (1986) Biol Neonate , vol.49 , pp. 85-89
    • de Grauw, T.J.1    Myers, R.E.2    Scott, W.J.3
  • 18
    • 0037404443 scopus 로고    scopus 로고
    • Genetic models in applied physiology: Invited review: effect of oxygen deprivation on cell cycle activity: a profile of delay and arrest
    • Douglas RM, Haddad GG. Genetic models in applied physiology: invited review: effect of oxygen deprivation on cell cycle activity: a profile of delay and arrest. J Appl Physiol 94: 2068-2084, 2003.
    • (2003) J Appl Physiol , vol.94 , pp. 2068-2084
    • Douglas, R.M.1    Haddad, G.G.2
  • 20
    • 0038293080 scopus 로고    scopus 로고
    • Prognostic significance of tumor oxygenation in humans
    • Evans SM, Koch CJ. Prognostic significance of tumor oxygenation in humans. Cancer Lett 195: 1-16, 2003.
    • (2003) Cancer Lett , vol.195 , pp. 1-16
    • Evans, S.M.1    Koch, C.J.2
  • 21
    • 0025336624 scopus 로고
    • Direct embryotoxicity of cocaine in rats: Effects on mitochondrial activity, cardiac function, and growth and development in vitro
    • Fantel AG, Person RE, Burroughs-Gleim CJ, Mackler B. Direct embryotoxicity of cocaine in rats: effects on mitochondrial activity, cardiac function, and growth and development in vitro. Teratology 42: 35-43, 1990.
    • (1990) Teratology , vol.42 , pp. 35-43
    • Fantel, A.G.1    Person, R.E.2    Burroughs-Gleim, C.J.3    Mackler, B.4
  • 23
    • 0036554972 scopus 로고    scopus 로고
    • Effects of prevailing hypoxaemia, acidaemia or hypoglycaemia upon the cardiovascular, endocrine and metabolic responses to acute hypoxaemia in the ovine fetus
    • Gardner DS, Fletcher AJ, Bloomfield MR, Fowden AL, Giussani DA. Effects of prevailing hypoxaemia, acidaemia or hypoglycaemia upon the cardiovascular, endocrine and metabolic responses to acute hypoxaemia in the ovine fetus. J Physiol 540: 351-366, 2002.
    • (2002) J Physiol , vol.540 , pp. 351-366
    • Gardner, D.S.1    Fletcher, A.J.2    Bloomfield, M.R.3    Fowden, A.L.4    Giussani, D.A.5
  • 24
    • 4444257379 scopus 로고    scopus 로고
    • The biology of hypoxia: The role of oxygen sensing in development, normal function, and disease
    • Giaccia AJ, Simon MC, Johnson R. The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease. Genes Dev 18: 2183-2194, 2004.
    • (2004) Genes Dev , vol.18 , pp. 2183-2194
    • Giaccia, A.J.1    Simon, M.C.2    Johnson, R.3
  • 25
    • 34548661469 scopus 로고    scopus 로고
    • Hypoxia, fetal growth and developmental origins of health and disease
    • edited by Wintour E and Owens JA. New York, NY: Springer Verlag
    • Giussani DA. Hypoxia, fetal growth and developmental origins of health and disease. In: Early Life Origins of Health and Disease, edited by Wintour E and Owens JA. New York, NY: Springer Verlag, 2006, p. 219-224.
    • (2006) Early Life Origins of Health and Disease , pp. 219-224
    • Giussani, D.A.1
  • 27
    • 84958698224 scopus 로고
    • Experimental production of congenital anomalies; timing and degree of anoxia as factors causing fetal deaths and congenital anomalies in the mouse
    • Ingalls TH, Curley FJ, Prindle RA. Experimental production of congenital anomalies; timing and degree of anoxia as factors causing fetal deaths and congenital anomalies in the mouse. N Engl J Med 247: 758-768, 1952.
    • (1952) N Engl J Med , vol.247 , pp. 758-768
    • Ingalls, T.H.1    Curley, F.J.2    Prindle, R.A.3
  • 31
    • 0016334266 scopus 로고
    • The effects of moderate hypoxia and moderate hypoxia plus hypercapnea on cardiac development in chick embryos
    • Jaffee OC. The effects of moderate hypoxia and moderate hypoxia plus hypercapnea on cardiac development in chick embryos. Teratology 10: 275-281, 1974.
    • (1974) Teratology , vol.10 , pp. 275-281
    • Jaffee, O.C.1
  • 33
    • 0030802218 scopus 로고    scopus 로고
    • The effect of high altitude and other risk factors on birthweight: Independent or interactive effects?
    • Jensen GM, Moore LG. The effect of high altitude and other risk factors on birthweight: independent or interactive effects? Am J Public Health 87: 1003-1007, 1997.
    • (1997) Am J Public Health , vol.87 , pp. 1003-1007
    • Jensen, G.M.1    Moore, L.G.2
  • 34
    • 0028952534 scopus 로고
    • Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice
    • Kwee L, Baldwin HS, Shen HM, Stewart CL, Buck C, Buck CA, Labow MA. Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice. Development 121: 489-503, 1995.
    • (1995) Development , vol.121 , pp. 489-503
    • Kwee, L.1    Baldwin, H.S.2    Shen, H.M.3    Stewart, C.L.4    Buck, C.5    Buck, C.A.6    Labow, M.A.7
  • 35
    • 11244306331 scopus 로고    scopus 로고
    • Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo
    • Lavine KJ, Yu K, White AC, Zhang X, Smith C, Partanen J, Ornitz DM. Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. Dev Cell 8: 85-95, 2005.
    • (2005) Dev Cell , vol.8 , pp. 85-95
    • Lavine, K.J.1    Yu, K.2    White, A.C.3    Zhang, X.4    Smith, C.5    Partanen, J.6    Ornitz, D.M.7
  • 36
    • 0035142809 scopus 로고    scopus 로고
    • Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: A possible signal for vessel development
    • Lee YM, Jeong CH, Koo SY, Son MJ, Song HS, Bae SK, Raleigh JA, Chung HY, Yoo MA, Kim KW. Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: A possible signal for vessel development. Dev Dyn 220: 175-186, 2001.
    • (2001) Dev Dyn , vol.220 , pp. 175-186
    • Lee, Y.M.1    Jeong, C.H.2    Koo, S.Y.3    Son, M.J.4    Song, H.S.5    Bae, S.K.6    Raleigh, J.A.7    Chung, H.Y.8    Yoo, M.A.9    Kim, K.W.10
  • 37
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
    • Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75: 59-72, 1993.
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, J.P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 38
    • 0028940132 scopus 로고
    • Chronic maternal hypoxia retards fetal growth and increases glucose utilization of select fetal tissues in the rat
    • Lueder FL, Kim SB, Buroker CA, Bangalore SA, Ogata ES. Chronic maternal hypoxia retards fetal growth and increases glucose utilization of select fetal tissues in the rat. Metab Clin Exp 44: 532-537, 1995.
    • (1995) Metab Clin Exp , vol.44 , pp. 532-537
    • Lueder, F.L.1    Kim, S.B.2    Buroker, C.A.3    Bangalore, S.A.4    Ogata, E.S.5
  • 39
    • 0026726467 scopus 로고
    • Prolonged hypoxia induced by the reduction of maternal uterine blood flow alters insulin-like growth factor-binding protein-1 (IGFBP-1) and IGFBP-2 gene expression in the ovine fetus
    • McLellan KC, Hooper SB, Bocking AD, Delhanty PJ, Phillips ID, Hill DJ, Han VK. Prolonged hypoxia induced by the reduction of maternal uterine blood flow alters insulin-like growth factor-binding protein-1 (IGFBP-1) and IGFBP-2 gene expression in the ovine fetus. Endocrinology 131: 1619-1628, 1992.
    • (1992) Endocrinology , vol.131 , pp. 1619-1628
    • McLellan, K.C.1    Hooper, S.B.2    Bocking, A.D.3    Delhanty, P.J.4    Phillips, I.D.5    Hill, D.J.6    Han, V.K.7
  • 41
    • 0023682977 scopus 로고
    • Use of bromodeoxyuridine- immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system
    • Miller MW, Nowakowski RS. Use of bromodeoxyuridine- immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system. Brain Res 457: 44-52, 1988.
    • (1988) Brain Res , vol.457 , pp. 44-52
    • Miller, M.W.1    Nowakowski, R.S.2
  • 42
    • 0023190464 scopus 로고
    • Protein synthesis during hypoxia in fetal lambs
    • Milley JR. Protein synthesis during hypoxia in fetal lambs. Am J Physiol Endocrinol Metab 252: E519-E524, 1987.
    • (1987) Am J Physiol Endocrinol Metab , vol.252
    • Milley, J.R.1
  • 43
    • 0028896312 scopus 로고
    • Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development
    • Mima T, Ueno H, Fischman DA, Williams LT, Mikawa T. Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development. Proc Natl Acad Sci USA 92: 467-471, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 467-471
    • Mima, T.1    Ueno, H.2    Fischman, D.A.3    Williams, L.T.4    Mikawa, T.5
  • 44
    • 0041629292 scopus 로고    scopus 로고
    • Fetal growth restriction and maternal oxygen transport during high altitude pregnancy
    • Moore LG. Fetal growth restriction and maternal oxygen transport during high altitude pregnancy. High Alt Med Biol 4: 141-156, 2003.
    • (2003) High Alt Med Biol , vol.4 , pp. 141-156
    • Moore, L.G.1
  • 46
    • 0034666038 scopus 로고    scopus 로고
    • Developmental changes in plasma catecholamine concentrations during normoxia and acute hypoxia in the chick embryo
    • Mulder AL, Golde JM, Goor AA, Giussani DA, Blanco CE. Developmental changes in plasma catecholamine concentrations during normoxia and acute hypoxia in the chick embryo. J Physiol 527: 593-599, 2000.
    • (2000) J Physiol , vol.527 , pp. 593-599
    • Mulder, A.L.1    Golde, J.M.2    Goor, A.A.3    Giussani, D.A.4    Blanco, C.E.5
  • 47
    • 0037205320 scopus 로고    scopus 로고
    • Cardiomyocyte cell cycle regulation
    • Pasumarthi KB, Field LJ. Cardiomyocyte cell cycle regulation. Circ Res 90: 1044-1054, 2002.
    • (2002) Circ Res , vol.90 , pp. 1044-1054
    • Pasumarthi, K.B.1    Field, L.J.2
  • 48
    • 0141816681 scopus 로고    scopus 로고
    • Epicardium is required for the full rate of myocyte proliferation and levels of expression of myocyte mitogenic factors FGF2 and its receptor, FGFR-1, but not for transmural myocardial patterning in the embryonic chick heart
    • Pennisi DJ, Ballard VL, Mikawa T. Epicardium is required for the full rate of myocyte proliferation and levels of expression of myocyte mitogenic factors FGF2 and its receptor, FGFR-1, but not for transmural myocardial patterning in the embryonic chick heart. Dev Dyn 228: 161-172, 2003.
    • (2003) Dev Dyn , vol.228 , pp. 161-172
    • Pennisi, D.J.1    Ballard, V.L.2    Mikawa, T.3
  • 49
    • 0034966299 scopus 로고    scopus 로고
    • Hypoxia regulates insulin-like growth factor-binding protein 1 in human fetal hepatocytes in primary culture: Suggestive molecular mechanisms for in utero fetal growth restriction caused by uteroplacental insufficiency
    • Popovici RM, Lu M, Bhatia S, Faessen GH, Giaccia AJ, Giudice LC. Hypoxia regulates insulin-like growth factor-binding protein 1 in human fetal hepatocytes in primary culture: suggestive molecular mechanisms for in utero fetal growth restriction caused by uteroplacental insufficiency. J Clin Endocrinol Metab 86: 2653-2659, 2001.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2653-2659
    • Popovici, R.M.1    Lu, M.2    Bhatia, S.3    Faessen, G.H.4    Giaccia, A.J.5    Giudice, L.C.6
  • 51
    • 0032801526 scopus 로고    scopus 로고
    • Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors
    • Raleigh JA, Chou SC, Arteel GE, Horsman MR. Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors. Radiat Res 151: 580-589, 1999.
    • (1999) Radiat Res , vol.151 , pp. 580-589
    • Raleigh, J.A.1    Chou, S.C.2    Arteel, G.E.3    Horsman, M.R.4
  • 52
    • 0032053169 scopus 로고    scopus 로고
    • Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression
    • Ratcliffe PJ, O'Rourke JF, Maxwell PH, Pugh CW. Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J Exp Biol 201: 1153-1162, 1998.
    • (1998) J Exp Biol , vol.201 , pp. 1153-1162
    • Ratcliffe, P.J.1    O'Rourke, J.F.2    Maxwell, P.H.3    Pugh, C.W.4
  • 53
    • 0037047647 scopus 로고    scopus 로고
    • Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes
    • Regula KM, Ens K, Kirshenbaum LA. Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes. Circ Res 91: 226-231, 2002.
    • (2002) Circ Res , vol.91 , pp. 226-231
    • Regula, K.M.1    Ens, K.2    Kirshenbaum, L.A.3
  • 54
    • 0030046595 scopus 로고    scopus 로고
    • Mouse mutants and cardiac development: New molecular insights into cardiogenesis
    • Rossant J. Mouse mutants and cardiac development: new molecular insights into cardiogenesis. Circ Res 78: 349-353, 1996.
    • (1996) Circ Res , vol.78 , pp. 349-353
    • Rossant, J.1
  • 55
  • 57
    • 0035313697 scopus 로고    scopus 로고
    • HIF-1 and mechanisms of hypoxia sensing
    • Semenza GL. HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol 13: 167-171, 2001.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 167-171
    • Semenza, G.L.1
  • 60
    • 0022446313 scopus 로고
    • Blood gases and acid-base status of the human second-trimester fetus
    • Soothill PW, Nicolaides KH, Rodeck CH, Gamsu H. Blood gases and acid-base status of the human second-trimester fetus. Obstet Gynecol 68: 173-176, 1986.
    • (1986) Obstet Gynecol , vol.68 , pp. 173-176
    • Soothill, P.W.1    Nicolaides, K.H.2    Rodeck, C.H.3    Gamsu, H.4
  • 61
    • 0022387931 scopus 로고
    • Effects of hypoxia on adult and neonatal pacemaker rates
    • Stowe DF, Bosnjak ZJ, Kampine JP. Effects of hypoxia on adult and neonatal pacemaker rates. Obstet Gynecol 66: 649-656, 1985.
    • (1985) Obstet Gynecol , vol.66 , pp. 649-656
    • Stowe, D.F.1    Bosnjak, Z.J.2    Kampine, J.P.3
  • 62
    • 0037443954 scopus 로고    scopus 로고
    • Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation
    • Stuckmann I, Evans S, Lassar AB. Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation. Dev Biol 255: 334-349, 2003.
    • (2003) Dev Biol , vol.255 , pp. 334-349
    • Stuckmann, I.1    Evans, S.2    Lassar, A.B.3
  • 63
    • 0015850358 scopus 로고
    • Comparison of the responses of fetal and adult cardiac muscle to hypoxia
    • Su JY, Friedman WF. Comparison of the responses of fetal and adult cardiac muscle to hypoxia. Am J Physiol 224: 1249-1253, 1973.
    • (1973) Am J Physiol , vol.224 , pp. 1249-1253
    • Su, J.Y.1    Friedman, W.F.2
  • 64
    • 0028175195 scopus 로고
    • RXRα mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis
    • Sucov HM, Dyson E, Gumeringer CL, Price J, Chien KR, Evans RM. RXRα mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev 8: 1007-1018, 1994.
    • (1994) Genes Dev , vol.8 , pp. 1007-1018
    • Sucov, H.M.1    Dyson, E.2    Gumeringer, C.L.3    Price, J.4    Chien, K.R.5    Evans, R.M.6
  • 65
    • 4344655389 scopus 로고    scopus 로고
    • Hypoxia-responsive signaling regulates the apoptosis-dependent remodeling of the embryonic avian cardiac outflow tract
    • Sugishita Y, Leifer DW, Agani F, Watanabe M, Fisher SA. Hypoxia-responsive signaling regulates the apoptosis-dependent remodeling of the embryonic avian cardiac outflow tract. Dev Biol 273: 285-296, 2004.
    • (2004) Dev Biol , vol.273 , pp. 285-296
    • Sugishita, Y.1    Leifer, D.W.2    Agani, F.3    Watanabe, M.4    Fisher, S.A.5
  • 66
    • 1542297346 scopus 로고    scopus 로고
    • Role of myocardial hypoxia in the remodeling of the embryonic avian cardiac outflow tract
    • Sugishita Y, Watanabe M, Fisher SA. Role of myocardial hypoxia in the remodeling of the embryonic avian cardiac outflow tract. Dev Biol 267: 294-308, 2004.
    • (2004) Dev Biol , vol.267 , pp. 294-308
    • Sugishita, Y.1    Watanabe, M.2    Fisher, S.A.3
  • 67
    • 0026545507 scopus 로고
    • BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone
    • Takahashi T, Nowakowski RS, Caviness VS Jr. BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone. J Neurocytol 21: 185-197, 1992.
    • (1992) J Neurocytol , vol.21 , pp. 185-197
    • Takahashi, T.1    Nowakowski, R.S.2    Caviness Jr, V.S.3
  • 68
    • 0029026103 scopus 로고
    • The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall
    • Takahashi T, Nowakowski RS, Caviness VS Jr. The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall. J Neurosci 15: 6046-6057, 1995.
    • (1995) J Neurosci , vol.15 , pp. 6046-6057
    • Takahashi, T.1    Nowakowski, R.S.2    Caviness Jr., V.S.3
  • 70
    • 0028287587 scopus 로고
    • Maternal hypoxia as a model for intrauterine growth retardation: Effects on insulin-like growth factors and their binding proteins
    • Tapanainen PJ, Bang P, Wilson K, Unterman TG, Vreman HJ, Rosenfeld RG. Maternal hypoxia as a model for intrauterine growth retardation: effects on insulin-like growth factors and their binding proteins. Pediatr Res 36: 152-158, 1994.
    • (1994) Pediatr Res , vol.36 , pp. 152-158
    • Tapanainen, P.J.1    Bang, P.2    Wilson, K.3    Unterman, T.G.4    Vreman, H.J.5    Rosenfeld, R.G.6
  • 73
    • 0032964554 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression coincides with coronary vasculogenesis and angiogenesis
    • Tomanek RJ, Ratajska A, Kitten GT, Yue X, Sandra A. Vascular endothelial growth factor expression coincides with coronary vasculogenesis and angiogenesis. Dev Dyn 215: 54-61, 1999.
    • (1999) Dev Dyn , vol.215 , pp. 54-61
    • Tomanek, R.J.1    Ratajska, A.2    Kitten, G.T.3    Yue, X.4    Sandra, A.5
  • 74
    • 0037050022 scopus 로고    scopus 로고
    • The failing heart
    • Towbin JA, Bowles NE. The failing heart. Nature 415: 227-233, 2002.
    • (2002) Nature , vol.415 , pp. 227-233
    • Towbin, J.A.1    Bowles, N.E.2
  • 76
    • 0023764310 scopus 로고
    • Altitude, low birth weight, and infant mortality in Colorado
    • Unger C, Weiser JK, McCullough RE, Keefer S, Moore LG. Altitude, low birth weight, and infant mortality in Colorado. JAMA 259: 3427-3432, 1988.
    • (1988) JAMA , vol.259 , pp. 3427-3432
    • Unger, C.1    Weiser, J.K.2    McCullough, R.E.3    Keefer, S.4    Moore, L.G.5
  • 77
    • 0024371776 scopus 로고
    • Effects of localised tumour hyperthermia on pimonidazole (Ro 03-8799) pharmacokinetics in mice
    • Walton MI, Bleehen NM, Workman P. Effects of localised tumour hyperthermia on pimonidazole (Ro 03-8799) pharmacokinetics in mice. Br J Cancer 59: 667-673, 1989.
    • (1989) Br J Cancer , vol.59 , pp. 667-673
    • Walton, M.I.1    Bleehen, N.M.2    Workman, P.3
  • 78
    • 0026686438 scopus 로고
    • Molecular regulation of cardiac myocyte adaptations to chronic hypoxia
    • Webster KA, Bishopric NH. Molecular regulation of cardiac myocyte adaptations to chronic hypoxia. J Mol Cell Cardiol 24: 741-751, 1992.
    • (1992) J Mol Cell Cardiol , vol.24 , pp. 741-751
    • Webster, K.A.1    Bishopric, N.H.2
  • 79
    • 0036320934 scopus 로고    scopus 로고
    • 2-regulated gene expression
    • 2-regulated gene expression. FASEB J 16: 1151-1162, 2002.
    • (2002) FASEB J , vol.16 , pp. 1151-1162
    • Wenger, R.H.1
  • 80
    • 0042631197 scopus 로고    scopus 로고
    • Effects of chronic hypoxia on maternal vasodilation and vascular reactivity in guinea pig and ovine pregnancy
    • White MM, Zhang L. Effects of chronic hypoxia on maternal vasodilation and vascular reactivity in guinea pig and ovine pregnancy. High Alt Med Biol 4: 157-169, 2003.
    • (2003) High Alt Med Biol , vol.4 , pp. 157-169
    • White, M.M.1    Zhang, L.2
  • 81
    • 0014975066 scopus 로고
    • Long-term maintenance of spontaneously beating mouse hearts in organ culture
    • Wildenthal K. Long-term maintenance of spontaneously beating mouse hearts in organ culture. J Appl Physiol 30: 153-157, 1971.
    • (1971) J Appl Physiol , vol.30 , pp. 153-157
    • Wildenthal, K.1
  • 82
    • 12344261629 scopus 로고    scopus 로고
    • Differential effects of maternal hypoxia or nutrient restriction on carotid and femoral vascular function in neonatal rats
    • Williams SJ, Campbell ME, McMillen IC, Davidge ST. Differential effects of maternal hypoxia or nutrient restriction on carotid and femoral vascular function in neonatal rats. Am J Physiol Regul Integr Comp Physiol 288: R360-R367, 2005.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Williams, S.J.1    Campbell, M.E.2    McMillen, I.C.3    Davidge, S.T.4
  • 83
    • 0032824560 scopus 로고    scopus 로고
    • Inactivation of erythropoietin leads to defects in cardiac morphogenesis
    • Wu H, Lee SH, Gao J, Liu X, Iruela-Arispe ML. Inactivation of erythropoietin leads to defects in cardiac morphogenesis. Development 126: 3597-3605, 1999.
    • (1999) Development , vol.126 , pp. 3597-3605
    • Wu, H.1    Lee, S.H.2    Gao, J.3    Liu, X.4    Iruela-Arispe, M.L.5
  • 84
    • 0033772467 scopus 로고    scopus 로고
    • Chronic hypoxia and developmental regulation of cytochrome c expression in rats
    • Xiao D, Ducsay CA, Zhang L. Chronic hypoxia and developmental regulation of cytochrome c expression in rats. J Soc Gynecol Investig 7: 279-283, 2000.
    • (2000) J Soc Gynecol Investig , vol.7 , pp. 279-283
    • Xiao, D.1    Ducsay, C.A.2    Zhang, L.3
  • 85
    • 33845637819 scopus 로고    scopus 로고
    • Hypoxia or nutrient restriction during pregnancy in rats leads to progressive cardiac remodeling and impairs postischemic recovery in adult male offspring
    • Xu Y, Williams SJ, O'Brien D, Davidge ST. Hypoxia or nutrient restriction during pregnancy in rats leads to progressive cardiac remodeling and impairs postischemic recovery in adult male offspring. FASEB J 20: 1251-1253, 2006.
    • (2006) FASEB J , vol.20 , pp. 1251-1253
    • Xu, Y.1    Williams, S.J.2    O'Brien, D.3    Davidge, S.T.4
  • 86
    • 0028955748 scopus 로고
    • Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development
    • Yang JT, Rayburn H, Hynes RO. Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development. Development 121: 549-560, 1995.
    • (1995) Development , vol.121 , pp. 549-560
    • Yang, J.T.1    Rayburn, H.2    Hynes, R.O.3
  • 87
    • 4644275138 scopus 로고    scopus 로고
    • HIF-1: The knowns and unknowns of hypoxia sensing
    • Zagorska A, Dulak J. HIF-1: the knowns and unknowns of hypoxia sensing. Acta Biochim Pol 51: 563-585, 2004.
    • (2004) Acta Biochim Pol , vol.51 , pp. 563-585
    • Zagorska, A.1    Dulak, J.2
  • 89
    • 11144288674 scopus 로고    scopus 로고
    • Prenatal hypoxia and cardiac programming
    • Zhang L. Prenatal hypoxia and cardiac programming. J Soc Gynecol Investig 12: 2-13, 2005.
    • (2005) J Soc Gynecol Investig , vol.12 , pp. 2-13
    • Zhang, L.1


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