-
1
-
-
0037040343
-
Mitochondrial PKC-ε and MAPK form signaling modules in the murine heart: Enhanced mitochondrial PKC-ε-MAPK interactions and differential MAPK activation in PKC-ε-induced cardio-protection
-
Baines CP, Zhang J, Wang GW, Zheng YT, Xiu JX, Cardwell EM, Bolli R, and Ping P. Mitochondrial PKC-ε and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKC-ε-MAPK interactions and differential MAPK activation in PKC-ε-induced cardio-protection. Circ Res 90: 390-397, 2002.
-
(2002)
Circ Res
, vol.90
, pp. 390-397
-
-
Baines, C.P.1
Zhang, J.2
Wang, G.W.3
Zheng, Y.T.4
Xiu, J.X.5
Cardwell, E.M.6
Bolli, R.7
Ping, P.8
-
2
-
-
0038163900
-
Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
-
Cai Z, Manalo DJ, Wei G, Rodriguez ER, Fox-Talbot K, Lu H, Zweier JL, and Semenza GL. Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation 108: 79-85, 2003.
-
(2003)
Circulation
, vol.108
, pp. 79-85
-
-
Cai, Z.1
Manalo, D.J.2
Wei, G.3
Rodriguez, E.R.4
Fox-Talbot, K.5
Lu, H.6
Zweier, J.L.7
Semenza, G.L.8
-
3
-
-
2442587705
-
Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injury
-
Cai Z and Semenza GL. Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injury. Circulation 109: 2050-2053, 2004.
-
(2004)
Circulation
, vol.109
, pp. 2050-2053
-
-
Cai, Z.1
Semenza, G.L.2
-
4
-
-
0034682786
-
2 sensing
-
2 sensing. J Biol Chem 275: 25130-25138, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 25130-25138
-
-
Chandel, N.S.1
McClintock, D.S.2
Feliciano, C.E.3
Wood, T.M.4
Melendez, J.A.5
Rodriguez, A.M.6
Schumacker, P.T.7
-
5
-
-
0142154635
-
Oxygen-dependent and -independent regulation of HIF-1α
-
Chun YS, Kim MS, and Park JW. Oxygen-dependent and -independent regulation of HIF-1α. J Korean Med Sci 17: 581-588, 2002.
-
(2002)
J Korean Med Sci
, vol.17
, pp. 581-588
-
-
Chun, Y.S.1
Kim, M.S.2
Park, J.W.3
-
6
-
-
0011743689
-
Heat acclimation improves cardiac contractility and ischemic tolerance. Is acclimation memorized?
-
Cohen O, Stern M, and Horowitz M. Heat acclimation improves cardiac contractility and ischemic tolerance. Is acclimation memorized? (Abstract.) J Mol Cell Cardiol 33: A22, 2001.
-
(2001)
(Abstract.) J Mol Cell Cardiol
, vol.33
-
-
Cohen, O.1
Stern, M.2
Horowitz, M.3
-
7
-
-
0032815353
-
Heme oxygenase and cardiac function in ischemic-reperfused rat hearts
-
Csonka C, Varga E, Kovacs P, Fernandy P, Blasing IE, Szilvassy Z, and Tosaki A. Heme oxygenase and cardiac function in ischemic-reperfused rat hearts. Free Radic Biol Med 27: 119-126, 1999.
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 119-126
-
-
Csonka, C.1
Varga, E.2
Kovacs, P.3
Fernandy, P.4
Blasing, I.E.5
Szilvassy, Z.6
Tosaki, A.7
-
8
-
-
0033027778
-
Does low thyroid hormone level switch on heat acclimation-induced changes in cardiac mechanical performance?
-
Eynan M, Palmon A, Hasin Y, and Horowitz M. Does low thyroid hormone level switch on heat acclimation-induced changes in cardiac mechanical performance? Am J Physiol Regul Integr Comp Physiol 276: R550-R558, 1999.
-
(1999)
Am J Physiol Regul Integr Comp Physiol
, vol.276
-
-
Eynan, M.1
Palmon, A.2
Hasin, Y.3
Horowitz, M.4
-
9
-
-
0036891997
-
Heat acclimation-induced elevated glycogen, glycolysis, and low thyroxine improve heart ischemic tolerance
-
Eynan M, Knubuvetz T, Meiri U, Navon G, Gerstenblith G, Bromberg Z, Hasin Y, and Horowitz M. Heat acclimation-induced elevated glycogen, glycolysis, and low thyroxine improve heart ischemic tolerance. J Appl Physiol 93: 2095-2104, 2002.
-
(2002)
J Appl Physiol
, vol.93
, pp. 2095-2104
-
-
Eynan, M.1
Knubuvetz, T.2
Meiri, U.3
Navon, G.4
Gerstenblith, G.5
Bromberg, Z.6
Hasin, Y.7
Horowitz, M.8
-
10
-
-
2442693041
-
Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression
-
Fandrey J. Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression. Am J Physiol Regul Integr Comp Physiol 286: R977-R988, 2004.
-
(2004)
Am J Physiol Regul Integr Comp Physiol
, vol.286
-
-
Fandrey, J.1
-
11
-
-
0033566693
-
Reciprocal positive regulation of hypoxia-inducible factor 1α and insulin-like growth factor 2
-
Feldser D, Agani F, Iyer NV, Pak B, Ferreira G, and Semenza GL. Reciprocal positive regulation of hypoxia-inducible factor 1α and insulin-like growth factor 2. Cancer Res 59: 3915-3918, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 3915-3918
-
-
Feldser, D.1
Agani, F.2
Iyer, N.V.3
Pak, B.4
Ferreira, G.5
Semenza, G.L.6
-
12
-
-
0037064010
-
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells
-
Fukuda R, Hirota K, Fan F, Jung YD, Ellis LM, and Semenza GL. Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J Biol Chem 277: 38205-38211, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 38205-38211
-
-
Fukuda, R.1
Hirota, K.2
Fan, F.3
Jung, Y.D.4
Ellis, L.M.5
Semenza, G.L.6
-
13
-
-
0033380593
-
Heat acclimation alters endothelial nitric oxide activity in the splanchnic vascular bed
-
Hadad W and Horowitz M. Heat acclimation alters endothelial nitric oxide activity in the splanchnic vascular bed. J Therm Biol 24: 403-408, 1999.
-
(1999)
J Therm Biol
, vol.24
, pp. 403-408
-
-
Hadad, W.1
Horowitz, M.2
-
14
-
-
0035991511
-
Recombinant human interleukin (IL)-1β-mediated regulation of hypoxia-inducible factor-1α (HIF-1α) stabilization, nuclear translocation and activation requires an antioxidant/reactive oxygen species (ROS)-sensitive mechanism
-
Haddad JJ. Recombinant human interleukin (IL)-1β-mediated regulation of hypoxia-inducible factor-1α (HIF-1α) stabilization, nuclear translocation and activation requires an antioxidant/reactive oxygen species (ROS)-sensitive mechanism. Eur Cytokine Netw 13: 250-260, 2002.
-
(2002)
Eur Cytokine Netw
, vol.13
, pp. 250-260
-
-
Haddad, J.J.1
-
15
-
-
0017103109
-
Acclimatization of rats to mild heat: Body water distribution and adaptability of submaxillary salivary gland
-
Horowitz M. Acclimatization of rats to mild heat: body water distribution and adaptability of submaxillary salivary gland. Pflügers Arch 366: 173-176, 1976.
-
(1976)
Pflügers Arch
, vol.366
, pp. 173-176
-
-
Horowitz, M.1
-
16
-
-
0036180660
-
From molecular and cellular to integrative heat defense during exposure to chronic heat
-
Horowitz M. From molecular and cellular to integrative heat defense during exposure to chronic heat. Comp Biochem Physiol A 131: 475-483, 2002.
-
(2002)
Comp Biochem Physiol A
, vol.131
, pp. 475-483
-
-
Horowitz, M.1
-
17
-
-
0345731130
-
Matching the heart to heat-induced circulatory load: Heat-acclimatory responses
-
Horowitz M. Matching the heart to heat-induced circulatory load: heat-acclimatory responses. News Physiol Sci 18: 215-221, 2003.
-
(2003)
News Physiol Sci
, vol.18
, pp. 215-221
-
-
Horowitz, M.1
-
18
-
-
0027408319
-
Central and peripheral contributions to control of heart rate during heat acclimation
-
Horowitz M and Meiri U. Central and peripheral contributions to control of heart rate during heat acclimation. Pflügers Arch 422: 386-392, 1993.
-
(1993)
Pflügers Arch
, vol.422
, pp. 386-392
-
-
Horowitz, M.1
Meiri, U.2
-
19
-
-
0020686272
-
Interrelationships between heat acclimation and salivary cooling mechanism in conscious rats
-
Horowitz M, Argov D, and Mizrahi R. Interrelationships between heat acclimation and salivary cooling mechanism in conscious rats. Comp Biochem Physiol A 74: 945-949, 1983.
-
(1983)
Comp Biochem Physiol A
, vol.74
, pp. 945-949
-
-
Horowitz, M.1
Argov, D.2
Mizrahi, R.3
-
20
-
-
4644309905
-
Stress related genomic responses during the course of heat acclimation and its association with ischemic/reperfusion cross-tolerance
-
Horowitz M, Eli-Berchoer L, Wapinski I, Friedman N, and Kodesh E. Stress related genomic responses during the course of heat acclimation and its association with ischemic/reperfusion cross-tolerance. J Appl Physiol 97: 1496-1507, 2004.
-
(2004)
J Appl Physiol
, vol.97
, pp. 1496-1507
-
-
Horowitz, M.1
Eli-Berchoer, L.2
Wapinski, I.3
Friedman, N.4
Kodesh, E.5
-
21
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α
-
Iyer NV, Kotch LE, Agani F, Leung SW, Laughner E, Wenger RH, Gassmann M, Gearhart JD, Lawler AM, Yu AY, and Semenza GL. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α. Genes Dev 12: 149-162, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, M.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
Semenza, G.L.11
-
22
-
-
0029944965
-
Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
-
Jiang BH, Rue E, Wang GL, Roe R, and Semenza GL. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J Biol Chem 271: 17771-17778, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 17771-17778
-
-
Jiang, B.H.1
Rue, E.2
Wang, G.L.3
Roe, R.4
Semenza, G.L.5
-
23
-
-
1642453685
-
Nitric oxide induces hypoxiainducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling
-
Kasuno K, Takabuchi S, Fukuda K, Kizaka-Kondoh S, Yodoi J, Adachi T, Semenza GL, and Hirota K. Nitric oxide induces hypoxiainducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling. J Biol Chem 279: 2550-2558, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 2550-2558
-
-
Kasuno, K.1
Takabuchi, S.2
Fukuda, K.3
Kizaka-Kondoh, S.4
Yodoi, J.5
Adachi, T.6
Semenza, G.L.7
Hirota, K.8
-
24
-
-
0037088576
-
Heat induction of the unphosphorylated form of hypoxia-inducible factor-1α is dependent on heat shock protein-90 activity
-
Katschinski DM, Le L, Heinrich D, Wagner KF, Hofer T, Schindler SG, and Wenger RH. Heat induction of the unphosphorylated form of hypoxia-inducible factor-1α is dependent on heat shock protein-90 activity. J Biol Chem 277: 9262-9267, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 9262-9267
-
-
Katschinski, D.M.1
Le, L.2
Heinrich, D.3
Wagner, K.F.4
Hofer, T.5
Schindler, S.G.6
Wenger, R.H.7
-
25
-
-
0033975850
-
Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: Control of hypoxia-inducible factor-1 activity by nitric oxide
-
Kimura H, Weisz A, Kurashima Y, Hashimoto K, Ogura T, D'Acquisto F, Addeo R, Makuuchi M, Esumi H. Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide. Blood 95: 189-197, 2000.
-
(2000)
Blood
, vol.95
, pp. 189-197
-
-
Kimura, H.1
Weisz, A.2
Kurashima, Y.3
Hashimoto, K.4
Ogura, T.5
D'Acquisto, F.6
Addeo, R.7
Makuuchi, M.8
Esumi, H.9
-
26
-
-
0344874751
-
Cell typespecific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1
-
Kelly BD, Hackett SF, Hirota K, Oshima Y, Cai Z, Berg-Dixon S, Rowan A, Yan Z, Campochiaro PA, and Semenza GL. Cell typespecific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1. Circ Res 93: 1074-1078, 2003.
-
(2003)
Circ Res
, vol.93
, pp. 1074-1078
-
-
Kelly, B.D.1
Hackett, S.F.2
Hirota, K.3
Oshima, Y.4
Cai, Z.5
Berg-Dixon, S.6
Rowan, A.7
Yan, Z.8
Campochiaro, P.A.9
Semenza, G.L.10
-
27
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
28
-
-
0035012605
-
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
-
Laughner E, Taghavi P, Chiles K, Mahon PC, and Semenza GL. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol 21: 3995-4004, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3995-4004
-
-
Laughner, E.1
Taghavi, P.2
Chiles, K.3
Mahon, P.C.4
Semenza, G.L.5
-
29
-
-
0027228264
-
Heat acclimation improves cardiac mechanics and metabolic performance during ischemia and reperfusion
-
Levi E, Vivi A, Hasin Y, Tassini M, Navon G, and Horowitz M. Heat acclimation improves cardiac mechanics and metabolic performance during ischemia and reperfusion. J Appl Physiol 75: 833-839, 1993.
-
(1993)
J Appl Physiol
, vol.75
, pp. 833-839
-
-
Levi, E.1
Vivi, A.2
Hasin, Y.3
Tassini, M.4
Navon, G.5
Horowitz, M.6
-
30
-
-
0033043766
-
Heat acclimation increases basal HSP72 level and alters its production dynamics during heat stress
-
Maloyan A, Palmon A, and Horowitz M. Heat acclimation increases basal HSP72 level and alters its production dynamics during heat stress. Am J Physiol Regul Integr Comp Physiol 276: R1506-R1515, 1999.
-
(1999)
Am J Physiol Regul Integr Comp Physiol
, vol.276
-
-
Maloyan, A.1
Palmon, A.2
Horowitz, M.3
-
31
-
-
0011741945
-
Heat-acclimation-ischemia cross-tolerance: Does HIF 1 play a role?
-
Maloyan A, Semenza G, Gerstenblith G, Stern M, and Horowitz M. Heat-acclimation-ischemia cross-tolerance: does HIF 1 play a role? (Abstract.) J Mol Cell Cardiol 33: A72, 2001.
-
(2001)
(Abstract.) J Mol Cell Cardiol
, vol.33
-
-
Maloyan, A.1
Semenza, G.2
Gerstenblith, G.3
Stern, M.4
Horowitz, M.5
-
32
-
-
0035985916
-
β-Adrenergic signaling and thyroid hormones affect HSP72 expression during heat acclimation
-
Maloyan A and Horowitz M. β-Adrenergic signaling and thyroid hormones affect HSP72 expression during heat acclimation. J Appl Physiol 93: 107-115, 2002.
-
(2002)
J Appl Physiol
, vol.93
, pp. 107-115
-
-
Maloyan, A.1
Horowitz, M.2
-
33
-
-
0042469448
-
Nitric oxide impairs normoxic degradation of HIF-1α by inhibition of prolyl hydroxylases
-
Metzen E, Zhou J, Jelkmann W, Fandrey J, Brune B. Nitric oxide impairs normoxic degradation of HIF-1α by inhibition of prolyl hydroxylases. Mol Biol Cell 14: 3470-3481, 2003.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 3470-3481
-
-
Metzen, E.1
Zhou, J.2
Jelkmann, W.3
Fandrey, J.4
Brune, B.5
-
34
-
-
0035983247
-
Heme oxygenase-1: The "emerging molecule" has arrived
-
Morse D and Choi AM. Heme oxygenase-1: the "emerging molecule" has arrived. Am J Respir Cell Mol Biol 27: 8-16, 2002.
-
(2002)
Am J Respir Cell Mol Biol
, vol.27
, pp. 8-16
-
-
Morse, D.1
Choi, A.M.2
-
35
-
-
0028263574
-
Is heat acclimation able to increase whole-body sensitivity to insulin?
-
Nagasawa J, Sato Y, Yamashita H, Ookawara T, Kizaki T, Habara Y, and Ohno H. Is heat acclimation able to increase whole-body sensitivity to insulin? Res Commun Chem Pathol Pharmacol 84: 375-378, 1994.
-
(1994)
Res Commun Chem Pathol Pharmacol
, vol.84
, pp. 375-378
-
-
Nagasawa, J.1
Sato, Y.2
Yamashita, H.3
Ookawara, T.4
Kizaki, T.5
Habara, Y.6
Ohno, H.7
-
36
-
-
0037073695
-
Induction of hypoxia-inducible factor-1 by transcriptional and translational mechanisms
-
Page EL, Robitaille GA, Pouysse'gur J, and Richard DE. Induction of hypoxia-inducible factor-1 by transcriptional and translational mechanisms. J Biol Chem 277: 48403-48409, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 48403-48409
-
-
Page, E.L.1
Robitaille, G.A.2
Pouysse'gur, J.3
Richard, D.E.4
-
37
-
-
0033673457
-
Normoxic stabilization of hypoxia-inducible factor-1 expression and activity: Redox-dependent effect of nitrogen oxides
-
Palmer LA, Gaston B, and Johns RA. Normoxic stabilization of hypoxia-inducible factor-1 expression and activity: redox-dependent effect of nitrogen oxides. Mol Pharmacol 58: 1197-1203, 2000.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 1197-1203
-
-
Palmer, L.A.1
Gaston, B.2
Johns, R.A.3
-
38
-
-
0038788826
-
Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1α (HIF-1α): Role of cytoplasmic trapping of HIF-2α
-
Park SK, Dadak AM, Haase VH, Fontana L, Giaccia AJ, and Johnson RS. Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1α (HIF-1α): role of cytoplasmic trapping of HIF-2α. Mol Cell Biol 23: 4959-4971, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4959-4971
-
-
Park, S.K.1
Dadak, A.M.2
Haase, V.H.3
Fontana, L.4
Giaccia, A.J.5
Johnson, R.S.6
-
39
-
-
3142533071
-
Changes in gene expression associated with acclimation to constant temperatures and fluctuating daily temperatures in an annual killifish Austrofundulus limnaeus
-
Podrabsky JE and Somero GN. Changes in gene expression associated with acclimation to constant temperatures and fluctuating daily temperatures in an annual killifish Austrofundulus limnaeus. J Exp Biol 207: 2237-2254, 2004.
-
(2004)
J Exp Biol
, vol.207
, pp. 2237-2254
-
-
Podrabsky, J.E.1
Somero, G.N.2
-
40
-
-
0036018452
-
Climate variations and the physiological basis of temperature-dependent biogeography: Systemic to molecular hierarchy of thermal tolerance in animals
-
Portner HO. Climate variations and the physiological basis of temperature-dependent biogeography: systemic to molecular hierarchy of thermal tolerance in animals. Comp Biochem Physiol A 132: 739-761, 2002.
-
(2002)
Comp Biochem Physiol A
, vol.132
, pp. 739-761
-
-
Portner, H.O.1
-
41
-
-
0030937718
-
Activation of hypoxia-inducible factor-1; definition of regulatory domains within the α subunit
-
Pugh CW, O'Rourke JF, Nagao M, Gleadle JM, and Ratcliffe PJ. Activation of hypoxia-inducible factor-1; definition of regulatory domains within the α subunit. J Biol Chem 272: 11205-11214, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 11205-11214
-
-
Pugh, C.W.1
O'Rourke, J.F.2
Nagao, M.3
Gleadle, J.M.4
Ratcliffe, P.J.5
-
42
-
-
0034282388
-
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1α in vascular smooth muscle cells
-
Richard DE, Berra E, and Pouyssegur J. Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1α in vascular smooth muscle cells. J Biol Chem 275: 26765-26771, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 26765-26771
-
-
Richard, D.E.1
Berra, E.2
Pouyssegur, J.3
-
43
-
-
0001564716
-
Thermoregulatory responses to acute exercise-heat stress and heat acclimation
-
Bethesda, MD: Am Physiol Soc, sect. 4
-
Sawka MN, Wenger CB, and Pandolf KB. Thermoregulatory responses to acute exercise-heat stress and heat acclimation. In: Handbook of Physiology. Environmental Physiology. Bethesda, MD: Am Physiol Soc, 1996, sect. 4, vol. I, p. 157-187.
-
(1996)
Handbook of Physiology. Environmental Physiology
, vol.1
, pp. 157-187
-
-
Sawka, M.N.1
Wenger, C.B.2
Pandolf, K.B.3
-
44
-
-
8344237449
-
Hydroxylation of HIF-1: Oxygen sensing at the molecular level
-
Semenza GL. Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology 19: 176-182, 2004.
-
(2004)
Physiology
, vol.19
, pp. 176-182
-
-
Semenza, G.L.1
-
45
-
-
3042829493
-
Hypoxic stress tolerance of the blind subterranean mole rat: Expression of erythropoietin and hypoxia-inducible factor 1α
-
Shams I, Avivi A, and Nevo E. Hypoxic stress tolerance of the blind subterranean mole rat: expression of erythropoietin and hypoxia-inducible factor 1α. Proc Natl Acad Sci USA 101: 9698-9703, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9698-9703
-
-
Shams, I.1
Avivi, A.2
Nevo, E.3
-
46
-
-
0035159670
-
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
-
Stroka DM, Burkharedt T, Desbaillets I, Wenger RH, Neil DAH, Bauer C, Gassmann M, and Candinas D. HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J 15: 2445-2453, 2001.
-
(2001)
FASEB J
, vol.15
, pp. 2445-2453
-
-
Stroka, D.M.1
Burkharedt, T.2
Desbaillets, I.3
Wenger, R.H.4
Neil, D.A.H.5
Bauer, C.6
Gassmann, M.7
Candinas, D.8
-
47
-
-
4143070143
-
Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia
-
Tissot van Patot MC, Bendrick-Peart J, Beckey VE, Serkova N, and Zwerdlinger L. Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia. Am J Physiol Lung Cell Mol Physiol 287: L525-L532, 2004.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Tissot Van Patot, M.C.1
Bendrick-Peart, J.2
Beckey, V.E.3
Serkova, N.4
Zwerdlinger, L.5
-
48
-
-
0041659121
-
Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway
-
Tramontano AF, Muniyappa R, Black AD, Blendea MC, Cohen I, Deng L, Sowers JR, Cutaia MV, and El-Sherif N. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochem Biophys Res Commun 308: 990-994, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.308
, pp. 990-994
-
-
Tramontano, A.F.1
Muniyappa, R.2
Black, A.D.3
Blendea, M.C.4
Cohen, I.5
Deng, L.6
Sowers, J.R.7
Cutaia, M.V.8
El-Sherif, N.9
-
49
-
-
0043128522
-
HIF-1 is required for heat acclimation in the nematode C. elegans
-
Treinin M, Shliar J, Jiang H, Powell-Coffman JA, Bromberg Z, and Horowitz M. HIF-1 is required for heat acclimation in the nematode C. elegans. Physiol Genomics 14: 17-24, 2003.
-
(2003)
Physiol Genomics
, vol.14
, pp. 17-24
-
-
Treinin, M.1
Shliar, J.2
Jiang, H.3
Powell-Coffman, J.A.4
Bromberg, Z.5
Horowitz, M.6
-
50
-
-
0037008770
-
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
-
Treins C, Giorgetti-Peraldi S, Murdaca J, Semenza GL, and Van Obberghen E. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway. J Biol Chem 277: 27975-27981, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 27975-27981
-
-
Treins, C.1
Giorgetti-Peraldi, S.2
Murdaca, J.3
Semenza, G.L.4
Van Obberghen, E.5
-
51
-
-
0036320934
-
2- regulated gene expression
-
2- regulated gene expression. FASEB J 16: 1152-1162, 2002.
-
(2002)
FASEB J
, vol.16
, pp. 1152-1162
-
-
Wenger, R.H.1
-
52
-
-
6344225691
-
Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury
-
Wright GL, Hanlon P, Amin K, Steenbergen C, Murphy E, and Arcasoy MO. Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury. FASEB J 18: 1031-1033, 2004.
-
(2004)
FASEB J
, vol.18
, pp. 1031-1033
-
-
Wright, G.L.1
Hanlon, P.2
Amin, K.3
Steenbergen, C.4
Murphy, E.5
Arcasoy, M.O.6
-
53
-
-
0031753986
-
Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung
-
Yu AY, Fri MG, Shimoda LA, Weiner CM, Stenmark K, and Semenza GL. Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung. Am J Physiol Lung Cell Mol Physiol 275: L818-L826, 1998.
-
(1998)
Am J Physiol Lung Cell Mol Physiol
, vol.275
-
-
Yu, A.Y.1
Fri, M.G.2
Shimoda, L.A.3
Weiner, C.M.4
Stenmark, K.5
Semenza, G.L.6
-
54
-
-
0032169214
-
Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1/ARNT
-
Zelzer E, Levy Y, Kahana C, Shilo B, Rubinstein M, and Cohen B. Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1/ARNT. EMBO J 17: 5085-5094, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 5085-5094
-
-
Zelzer, E.1
Levy, Y.2
Kahana, C.3
Shilo, B.4
Rubinstein, M.5
Cohen, B.6
-
55
-
-
0035005812
-
Mechanisms of coronary angiogenesis in response to stretch: Role of VEGF and TGF-β
-
Zheng W, Seftor EA, Meining CJ, Hendrix MJC, and Tomanek RJ. Mechanisms of coronary angiogenesis in response to stretch: role of VEGF and TGF-β. Am J Physiol Heart Circ Physiol 280: H909-H917, 2001.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Zheng, W.1
Seftor, E.A.2
Meining, C.J.3
Hendrix, M.J.C.4
Tomanek, R.J.5
-
56
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
-
Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, and Semenza GL. Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 60: 1541-1545, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
Laughner, E.4
Hanrahan, C.5
Georgescu, M.M.6
Simons, J.W.7
Semenza, G.L.8
-
57
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases
-
Zhong H, De Marzo AM, Laughner E, Lim M, Hilton DA, Zagzag D, Buechler P, Isaacs WB, Semenza GL, and Simons JW. Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases. Cancer Res 59: 5830-5835, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
Buechler, P.7
Isaacs, W.B.8
Semenza, G.L.9
Simons, J.W.10
-
58
-
-
1842691021
-
PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1α from pVHL-independent degradation
-
Zhou J, Schmid T, Frank R, and Brune B. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1α from pVHL-independent degradation. J Biol Chem 279: 13506-13513, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 13506-13513
-
-
Zhou, J.1
Schmid, T.2
Frank, R.3
Brune, B.4
|