메뉴 건너뛰기




Volumn 25, Issue 7, 2010, Pages 547-555

Review: Disruption of the postsynaptic density in Alzheimer's disease and other neurodegenerative dementias

Author keywords

Alzheimer's disease; dementia with Lewy bodies; frontotemporal dementia; postsynaptic density

Indexed keywords

ADAPTOR PROTEIN; AMPA RECEPTOR; APOLIPOPROTEIN E; CHOLINERGIC RECEPTOR; CYTOSKELETON PROTEIN; DOPAMINE RECEPTOR; EPHRIN; EPHRIN RECEPTOR; GLUTAMATE RECEPTOR; INSULIN RECEPTOR; INTEGRIN; LIPOPROTEIN RECEPTOR; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NERVE CELL ADHESION MOLECULE; SEROTONIN RECEPTOR;

EID: 77957954675     PISSN: 15333175     EISSN: None     Source Type: Journal    
DOI: 10.1177/1533317510382893     Document Type: Review
Times cited : (61)

References (121)
  • 1
    • 75749093076 scopus 로고    scopus 로고
    • Update on frontotemporal dementia
    • Arvanitakis Z. Update on frontotemporal dementia. Neurologist. 2010 ; 16 (1). 16-22.
    • (2010) Neurologist , vol.16 , Issue.1 , pp. 16-22
    • Arvanitakis, Z.1
  • 2
    • 34548036227 scopus 로고    scopus 로고
    • Tau mediated neurodegeneration in Alzheimer's disease and related disorders
    • Ballatore C., Lee VM, Trojanowski JQ Tau mediated neurodegeneration in Alzheimer's disease and related disorders. Nat Rev Neurosci. 2007 ; 8 (9). 663-672.
    • (2007) Nat Rev Neurosci , vol.8 , Issue.9 , pp. 663-672
    • Ballatore, C.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 3
    • 56749095159 scopus 로고    scopus 로고
    • New approaches to the treatment of frontotemporal lobar degeneration
    • Vossel KA, Miller BL New approaches to the treatment of frontotemporal lobar degeneration. Curr Opin Neurol. 2008 ; 21 (6). 708-716.
    • (2008) Curr Opin Neurol , vol.21 , Issue.6 , pp. 708-716
    • Vossel, K.A.1    Miller, B.L.2
  • 4
    • 33847239940 scopus 로고    scopus 로고
    • Structural principles of tau and the paired helical filaments of Alzheimer's disease
    • Mandelkow E., von Bergen M., Biernat J., Mandelkow EM Structural principles of tau and the paired helical filaments of Alzheimer's disease. Brain Pathol. 2007 ; 17 (1). 83-90.
    • (2007) Brain Pathol , vol.17 , Issue.1 , pp. 83-90
    • Mandelkow, E.1    Von Bergen, M.2    Biernat, J.3    Mandelkow, E.M.4
  • 5
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • Brun A., Passant U. Frontal lobe degeneration of non-Alzheimer type. Structural characteristics, diagnostic criteria and relation to other frontotemporal dementias. Acta Neurol Scand Suppl. 1996 ; 168: 28-30
    • Terry RD, Masliah E., Salmon DP, et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol. 1991 ; 30 (4). 572-580. 6. Brun A., Passant U. Frontal lobe degeneration of non-Alzheimer type. Structural characteristics, diagnostic criteria and relation to other frontotemporal dementias. Acta Neurol Scand Suppl. 1996 ; 168: 28-30.
    • (1991) Ann Neurol , vol.30 , Issue.4 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3
  • 6
    • 0031569804 scopus 로고    scopus 로고
    • Alzheimer's disease, Lewy body disease and aging: A comparative study of the perforant pathway
    • Lippa CF, Pulaski-Salo D., Dickson DW, Smith TW Alzheimer's disease, Lewy body disease and aging: a comparative study of the perforant pathway. J Neurol Sci. 1997 ; 147 (2). 161-166.
    • (1997) J Neurol Sci , vol.147 , Issue.2 , pp. 161-166
    • Lippa, C.F.1    Pulaski-Salo, D.2    Dickson, D.W.3    Smith, T.W.4
  • 7
    • 0034889802 scopus 로고    scopus 로고
    • Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementias
    • Lipton AM, Cullum CM, Satumtira S., et al. Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementias. Arch Neurol. 2001 ; 58 (8). 1233-1239.
    • (2001) Arch Neurol , vol.58 , Issue.8 , pp. 1233-1239
    • Lipton, A.M.1    Cullum, C.M.2    Satumtira, S.3
  • 8
    • 10044293212 scopus 로고    scopus 로고
    • Synaptophysin immunoreactivity in Picks disease: Comparison with Alzheimer's disease and dementia with Lewy bodies
    • Lippa CF Synaptophysin immunoreactivity in Picks disease: comparison with Alzheimer's disease and dementia with Lewy bodies. Am J Alzheimers Dis Other Demen. 2004 ; 19 (6). 341-344.
    • (2004) Am J Alzheimers Dis Other Demen , vol.19 , Issue.6 , pp. 341-344
    • Lippa, C.F.1
  • 9
    • 65649095945 scopus 로고    scopus 로고
    • Dementia with Lewy bodies and Parkinson's disease dementia may best be viewed as two distinct entities
    • Revuelta GJ, Lippa CF Dementia with Lewy bodies and Parkinson's disease dementia may best be viewed as two distinct entities. Int Psychogeriatr.; 2009 21 (2). 213-216.
    • Int Psychogeriatr.; , vol.21 , Issue.2 , pp. 213-216
    • Revuelta, G.J.1    Lippa, C.F.2
  • 10
    • 69449089052 scopus 로고    scopus 로고
    • Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease
    • Gong Y., Lippa CF, Zhu J., Lin Q., Rosso AL Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease. Brain Res. 2009 ; 1292: 191-198.
    • (2009) Brain Res , vol.1292 , pp. 191-198
    • Gong, Y.1    Lippa, C.F.2    Zhu, J.3    Lin, Q.4    Rosso, A.L.5
  • 11
    • 33748100357 scopus 로고    scopus 로고
    • Spine growth precedes synapse formation in the adult neocortex in vivo
    • Knott GW, Holtmaat A., Wilbrecht L., Welker E., Svoboda K. Spine growth precedes synapse formation in the adult neocortex in vivo. Nat Neurosci. 2006 ; 9 (9). 1117-1124.
    • (2006) Nat Neurosci , vol.9 , Issue.9 , pp. 1117-1124
    • Knott, G.W.1    Holtmaat, A.2    Wilbrecht, L.3    Welker, E.4    Svoboda, K.5
  • 12
    • 0024473444 scopus 로고
    • Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: Serial electron microscopy with reference to their biophysical characteristics
    • Harris KM, Stevens JK Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics. J Neurosci. 1989 ; 9 (8). 2982-2997.
    • (1989) J Neurosci , vol.9 , Issue.8 , pp. 2982-2997
    • Harris, K.M.1    Stevens, J.K.2
  • 13
    • 3843136369 scopus 로고    scopus 로고
    • A morphological correlate of synaptic scaling in visual cortex
    • Wallace W., Bear MF A morphological correlate of synaptic scaling in visual cortex. J Neurosci. 2004 ; 24 (31). 6928-6938.
    • (2004) J Neurosci , vol.24 , Issue.31 , pp. 6928-6938
    • Wallace, W.1    Bear, M.F.2
  • 14
    • 5044224260 scopus 로고    scopus 로고
    • PDZ domain proteins of synapses
    • Kim E., Sheng M. PDZ domain proteins of synapses. Nat Rev Neurosci. 2004 ; 5 (10). 771-781.
    • (2004) Nat Rev Neurosci , vol.5 , Issue.10 , pp. 771-781
    • Kim, E.1    Sheng, M.2
  • 16
    • 17044378032 scopus 로고    scopus 로고
    • Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons
    • Roussignol G., Ango F., Romorini S., et al. Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons. J Neurosci. 2005 ; 25 (14). 3560-3570.
    • (2005) J Neurosci , vol.25 , Issue.14 , pp. 3560-3570
    • Roussignol, G.1    Ango, F.2    Romorini, S.3
  • 17
    • 32344434917 scopus 로고    scopus 로고
    • A preformed complex of postsynaptic proteins is involved in excitatory synapse development
    • Gerrow K., Romorini S., Nabi SM, Colicos MA, Sala C., El-Husseini A. A preformed complex of postsynaptic proteins is involved in excitatory synapse development. Neuron. 2006 ; 49 (4). 547-562.
    • (2006) Neuron , vol.49 , Issue.4 , pp. 547-562
    • Gerrow, K.1    Romorini, S.2    Nabi, S.M.3    Colicos, M.A.4    Sala, C.5    El-Husseini, A.6
  • 18
    • 0037374587 scopus 로고    scopus 로고
    • Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system
    • Ehlers MD Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system. Nat Neurosci. 2003 ; 6 (3). 231-242.
    • (2003) Nat Neurosci , vol.6 , Issue.3 , pp. 231-242
    • Ehlers, M.D.1
  • 19
    • 0030025216 scopus 로고    scopus 로고
    • Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease
    • Harigaya Y., Shoji M., Shirao T., Hirai S. Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease. J Neurosci Res. 1996 ; 43 (1). 87-92.
    • (1996) J Neurosci Res , vol.43 , Issue.1 , pp. 87-92
    • Harigaya, Y.1    Shoji, M.2    Shirao, T.3    Hirai, S.4
  • 20
    • 0037166050 scopus 로고    scopus 로고
    • Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome
    • Shim KS, Lubec G. Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome. Neurosci Lett. 2002 ; 324 (3). 209-212.
    • (2002) Neurosci Lett , vol.324 , Issue.3 , pp. 209-212
    • Shim, K.S.1    Lubec, G.2
  • 21
    • 0035654078 scopus 로고    scopus 로고
    • Dendritic spines: Structure, dynamics and regulation
    • Hering H., Sheng M. Dendritic spines: structure, dynamics and regulation. Nat Rev Neurosci. 2001 ; 2 (12). 880-888.
    • (2001) Nat Rev Neurosci , vol.2 , Issue.12 , pp. 880-888
    • Hering, H.1    Sheng, M.2
  • 22
    • 0034928790 scopus 로고    scopus 로고
    • Morphological changes in dendritic spines associated with long-term synaptic plasticity
    • Yuste R., Bonhoeffer T. Morphological changes in dendritic spines associated with long-term synaptic plasticity. Annu Rev Neurosci. 2001 ; 24: 1071-1089.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 1071-1089
    • Yuste, R.1    Bonhoeffer, T.2
  • 23
    • 15944369335 scopus 로고    scopus 로고
    • Spine architecture and synaptic plasticity
    • Carlisle HJ, Kennedy MB Spine architecture and synaptic plasticity. Trends Neurosci. 2005 ; 28 (4). 182-187.
    • (2005) Trends Neurosci , vol.28 , Issue.4 , pp. 182-187
    • Carlisle, H.J.1    Kennedy, M.B.2
  • 24
    • 0042838303 scopus 로고    scopus 로고
    • Alzheimer's disease-affected brain: Presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss
    • Gong Y., Chang L., Viola KL, et al. Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss. Proc Natl Acad Sci U S A. 2003 ; 100 (18). 10417-10422.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.18 , pp. 10417-10422
    • Gong, Y.1    Chang, L.2    Viola, K.L.3
  • 25
    • 20844458090 scopus 로고    scopus 로고
    • Synaptic targeting by Alzheimer's-related 2-amyloid oligomers
    • Lacor PN, Buniel MC, Chang L., et al. Synaptic targeting by Alzheimer's-related 2-amyloid oligomers. J Neurosci. 2004 ; 24 (45). 10191-10200.
    • (2004) J Neurosci , vol.24 , Issue.45 , pp. 10191-10200
    • Lacor, P.N.1    Buniel, M.C.2    Chang, L.3
  • 26
    • 1842732209 scopus 로고    scopus 로고
    • Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain
    • Takahashi RH, Almeida CG, Kearney PF, et al. Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain. J Neurosci. 2004 ; 24 (14). 3592-3599.
    • (2004) J Neurosci , vol.24 , Issue.14 , pp. 3592-3599
    • Takahashi, R.H.1    Almeida, C.G.2    Kearney, P.F.3
  • 27
    • 62649174753 scopus 로고    scopus 로고
    • Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
    • Koffie RM, Meyer-Luehmann M., Hashimoto T., et al. Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques. Proc Natl Acad Sci U S A. 2009 ; 106 (10). 4012-4007.
    • (2009) Proc Natl Acad Sci U S A. , vol.106 , Issue.10 , pp. 4012-4007
    • Koffie, R.M.1    Meyer-Luehmann, M.2    Hashimoto, T.3
  • 28
    • 33748949432 scopus 로고    scopus 로고
    • The postsynaptic density
    • Boeckers TM The postsynaptic density. Cell Tissue Res. 2006 ; 326 (2). 409-422.
    • (2006) Cell Tissue Res , vol.326 , Issue.2 , pp. 409-422
    • Boeckers, T.M.1
  • 29
    • 0034721678 scopus 로고    scopus 로고
    • Signal-processing machines at the postsynaptic density
    • Kennedy MB Signal-processing machines at the postsynaptic density. Science. 2000 ; 290 (5492). 750-754.
    • (2000) Science , vol.290 , Issue.5492 , pp. 750-754
    • Kennedy, M.B.1
  • 30
    • 0035912750 scopus 로고    scopus 로고
    • Molecular organization of the postsynaptic specialization
    • Sheng M. Molecular organization of the postsynaptic specialization. Proc Natl Acad Sci U S A. 2001 ; 98 (13). 7058-7061.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.13 , pp. 7058-7061
    • Sheng, M.1
  • 31
    • 0345276572 scopus 로고    scopus 로고
    • Synaptic slaughter in Alzheimer's disease
    • Coleman PD, Yao PJ Synaptic slaughter in Alzheimer's disease. Neurobiol Aging. 2003 ; 24 (8). 1023-1027.
    • (2003) Neurobiol Aging , vol.24 , Issue.8 , pp. 1023-1027
    • Coleman, P.D.1    Yao, P.J.2
  • 32
    • 33947314641 scopus 로고    scopus 로고
    • Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
    • Shankar GM, Bloodgood BL, Townsend M., Walsh DM, Selkoe DJ, Sabatini BL Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J Neurosci. 2007 ; 27 (11). 2866-2875.
    • (2007) J Neurosci , vol.27 , Issue.11 , pp. 2866-2875
    • Shankar, G.M.1    Bloodgood, B.L.2    Townsend, M.3    Walsh, D.M.4    Selkoe, D.J.5    Sabatini, B.L.6
  • 33
    • 26844574739 scopus 로고    scopus 로고
    • NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production
    • Lesn S., Ali C., Gabriel C., et al. NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production. J Neurosci. 2005 ; 25 (41). 9367-9377.
    • (2005) J Neurosci , vol.25 , Issue.41 , pp. 9367-9377
    • Lesn, S.1    Ali, C.2    Gabriel, C.3
  • 34
    • 65549119787 scopus 로고    scopus 로고
    • Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production
    • Hoey SE, Williams RJ, Perkinton MS Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production. J Neurosci. 2009 ; 29 (14). 4442-4460.
    • (2009) J Neurosci , vol.29 , Issue.14 , pp. 4442-4460
    • Hoey, S.E.1    Williams, R.J.2    Perkinton, M.S.3
  • 35
    • 67449084098 scopus 로고    scopus 로고
    • Beta-Amyloid impairs AMPA receptor trafficking and function by reducing Ca2+/calmodulin-dependent protein kinase II synaptic distribution
    • Gu Z., Liu W., Yan Z. Beta-Amyloid impairs AMPA receptor trafficking and function by reducing Ca2+/calmodulin-dependent protein kinase II synaptic distribution. J Biol Chem. 2009 ; 284 (16). 10639-10649.
    • (2009) J Biol Chem. , vol.284 , Issue.16 , pp. 10639-10649
    • Gu, Z.1    Liu, W.2    Yan, Z.3
  • 36
    • 0028350662 scopus 로고
    • AMPA-selective glutamate receptor subtype immunoreactivity in the entorhinal cortex of non-demented elderly and patients with Alzheimer's disease
    • Armstrong DM, Ikonomovic MD, Sheffield R., Wenthold RJ AMPA-selective glutamate receptor subtype immunoreactivity in the entorhinal cortex of non-demented elderly and patients with Alzheimer's disease. Brain Res. 1994 ; 639 (2). 207-216.
    • (1994) Brain Res , vol.639 , Issue.2 , pp. 207-216
    • Armstrong, D.M.1    Ikonomovic, M.D.2    Sheffield, R.3    Wenthold, R.J.4
  • 37
    • 44749089401 scopus 로고    scopus 로고
    • Beta-amyloid and glutamate receptors
    • Gasparini L., Dityatev A. Beta-amyloid and glutamate receptors. Exp Neurol. 2008 ; 212 (1). 1-4.
    • (2008) Exp Neurol , vol.212 , Issue.1 , pp. 1-4
    • Gasparini, L.1    Dityatev, A.2
  • 39
    • 0030757919 scopus 로고    scopus 로고
    • MGluR modulation of post-traumatic neuronal death: Role of NMDA receptors
    • Mukhin AG, Ivanova SA, Faden AI mGluR modulation of post-traumatic neuronal death: role of NMDA receptors. Neuroreport. 1997 ; 8 (11). 2561-2566.
    • (1997) Neuroreport , vol.8 , Issue.11 , pp. 2561-2566
    • Mukhin, A.G.1    Ivanova, S.A.2    Faden, A.I.3
  • 40
    • 0033638723 scopus 로고    scopus 로고
    • Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism
    • O'Leary DM, Movsesyan V., Vicini S., Faden AI Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism. Br J Pharmacol. 2000 ; 131 (7). 1429-1437.
    • (2000) Br J Pharmacol , vol.131 , Issue.7 , pp. 1429-1437
    • O'Leary, D.M.1    Movsesyan, V.2    Vicini, S.3    Faden, A.I.4
  • 41
    • 0032970849 scopus 로고    scopus 로고
    • Beta-Amyloid-induced apoptosis of cerebellar granule cells and cortical neurons: Exacerbation by selective inhibition of group i metabotropic glutamate receptors
    • Allen JW, Eldadah BA, Faden AI Beta-Amyloid-induced apoptosis of cerebellar granule cells and cortical neurons: exacerbation by selective inhibition of group I metabotropic glutamate receptors. Neuropharmacology. 1999 ; 38 (8). 1243-1252.
    • (1999) Neuropharmacology , vol.38 , Issue.8 , pp. 1243-1252
    • Allen, J.W.1    Eldadah, B.A.2    Faden, A.I.3
  • 42
    • 27744583133 scopus 로고    scopus 로고
    • Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease-related changes
    • Albasanz JL, Dalf E., Ferrer I., Martán M. Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease-related changes. Neurobiol Dis. 2005 ; 20 (3). 685-693.
    • (2005) Neurobiol Dis , vol.20 , Issue.3 , pp. 685-693
    • Albasanz, J.L.1    Dalf, E.2    Ferrer, I.3    Martán, M.4
  • 43
    • 12444282640 scopus 로고    scopus 로고
    • Muscarinic receptors in basal ganglia in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease
    • Piggott MA, Owens J., O'Brien J., et al. Muscarinic receptors in basal ganglia in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease. J Chem Neuroanat. 2003 ; 25 (3). 161-173.
    • (2003) J Chem Neuroanat , vol.25 , Issue.3 , pp. 161-173
    • Piggott, M.A.1    Owens, J.2    O'Brien, J.3
  • 44
    • 0033624430 scopus 로고    scopus 로고
    • Morphological substrates of mental dysfunction in Lewy body disease: An update
    • Jellinger KA Morphological substrates of mental dysfunction in Lewy body disease: an update. J Neural Transm Suppl. 2000 ; 59: 185-212.
    • (2000) J Neural Transm Suppl , vol.59 , pp. 185-212
    • Jellinger, K.A.1
  • 45
    • 0037096306 scopus 로고    scopus 로고
    • Alpha7 nicotinic acetylcholine receptors occur at postsynaptic densities of AMPA receptor-positive and -negative excitatory synapses in rat sensory cortex
    • Levy RB, Aoki C. Alpha7 nicotinic acetylcholine receptors occur at postsynaptic densities of AMPA receptor-positive and -negative excitatory synapses in rat sensory cortex. J Neurosci. 2002 ; 22 (12). 5001-5015.
    • (2002) J Neurosci , vol.22 , Issue.12 , pp. 5001-5015
    • Levy, R.B.1    Aoki, C.2
  • 46
    • 23044445669 scopus 로고    scopus 로고
    • Regulation of NMDA receptor trafficking by amyloid-beta
    • Snyder EM, Nong Y., Almeida CG, et al. Regulation of NMDA receptor trafficking by amyloid-beta. Nat Neurosci. 2005 ; 8 (8). 1051-1058.
    • (2005) Nat Neurosci , vol.8 , Issue.8 , pp. 1051-1058
    • Snyder, E.M.1    Nong, Y.2    Almeida, C.G.3
  • 47
    • 34248534333 scopus 로고    scopus 로고
    • Insights into the role of dopamine receptor systems in learning and memory
    • El-Ghundi M., O'Dowd BF, George SR Insights into the role of dopamine receptor systems in learning and memory. Rev Neurosci. 2007 ; 18 (1). 37-66.
    • (2007) Rev Neurosci , vol.18 , Issue.1 , pp. 37-66
    • El-Ghundi, M.1    O'Dowd, B.F.2    George, S.R.3
  • 48
    • 34547664367 scopus 로고    scopus 로고
    • Modulation of D2R-NR2B interactions in response to cocaine
    • Liu XY, Chu XP, Mao LM, et al. Modulation of D2R-NR2B interactions in response to cocaine. Neuron. 2006 ; 52 (5). 897-909.
    • (2006) Neuron , vol.52 , Issue.5 , pp. 897-909
    • Liu, X.Y.1    Chu, X.P.2    Mao, L.M.3
  • 49
    • 0032536479 scopus 로고    scopus 로고
    • Dopamine D2 receptor bands in normal human temporal cortex are absent in Alzheimer's disease
    • Joyce JN, Myers AJ, Gurevich E. Dopamine D2 receptor bands in normal human temporal cortex are absent in Alzheimer's disease. Brain Res. 1998 ; 784 (1-2). 7-17.
    • (1998) Brain Res , vol.784 , Issue.1-2 , pp. 7-17
    • Joyce, J.N.1    Myers, A.J.2    Gurevich, E.3
  • 50
    • 0042668338 scopus 로고    scopus 로고
    • Hippocampal dopamine D2 receptors correlate with memory functions in Alzheimer's disease
    • Kemppainen N., Laine M., Laakso MP, et al. Hippocampal dopamine D2 receptors correlate with memory functions in Alzheimer's disease. Eur J Neurosci. 2003 ; 18 (1). 149-154.
    • (2003) Eur J Neurosci , vol.18 , Issue.1 , pp. 149-154
    • Kemppainen, N.1    Laine, M.2    Laakso, M.P.3
  • 51
    • 62149141359 scopus 로고    scopus 로고
    • Increased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer disease
    • Reeves S., Brown R., Howard R., Grasby P. Increased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer disease. Neurology. 2009 ; 72 (6). 528-534.
    • (2009) Neurology. , vol.72 , Issue.6 , pp. 528-534
    • Reeves, S.1    Brown, R.2    Howard, R.3    Grasby, P.4
  • 52
    • 34648816894 scopus 로고    scopus 로고
    • Selective loss of dopamine D2 receptors in temporal cortex in dementia with Lewy bodies, association with cognitive decline
    • Piggott MA, Ballard CG, Rowan E., et al. Selective loss of dopamine D2 receptors in temporal cortex in dementia with Lewy bodies, association with cognitive decline. Synapse. 2007 ; 61 (11). 903-911.
    • (2007) Synapse , vol.61 , Issue.11 , pp. 903-911
    • Piggott, M.A.1    Ballard, C.G.2    Rowan, E.3
  • 53
    • 17144385440 scopus 로고    scopus 로고
    • Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus
    • Hajszan T., MacLusky NJ, Leranth C. Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus. Eur J Neurosci. 2005 ; 21 (5). 1299-1303.
    • (2005) Eur J Neurosci , vol.21 , Issue.5 , pp. 1299-1303
    • Hajszan, T.1    MacLusky, N.J.2    Leranth, C.3
  • 55
    • 43449105012 scopus 로고    scopus 로고
    • Colocalisation of serotonin2A receptors with the glutamate receptor subunits NR1 and GluR2 in the dentate gyrus: An ultrastructural study of a modulatory role
    • Peddie CJ, Davies HA, Colyer FM, Stewart MG, Rodriguez JJ Colocalisation of serotonin2A receptors with the glutamate receptor subunits NR1 and GluR2 in the dentate gyrus: An ultrastructural study of a modulatory role. Exp Neurol. 2008 ; 211 (2). 561-573.
    • (2008) Exp Neurol , vol.211 , Issue.2 , pp. 561-573
    • Peddie, C.J.1    Davies, H.A.2    Colyer, F.M.3    Stewart, M.G.4    Rodriguez, J.J.5
  • 56
    • 66749118877 scopus 로고    scopus 로고
    • PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors
    • Abbas AI, Yadav PN, Yao WD, et al. PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. J Neurosci. 2009 ; 29 (22). 7124-7136.
    • (2009) J Neurosci. , vol.29 , Issue.22 , pp. 7124-7136
    • Abbas, A.I.1    Yadav, P.N.2    Yao, W.D.3
  • 57
    • 47749153338 scopus 로고    scopus 로고
    • Activation of 5-HT2A/ C receptors counteracts 5-HT1A regulation of n-methyl-D-aspartate receptor channels in pyramidal neurons of prefrontal cortex
    • Yuen EY, Jiang Q., Chen P., Feng J., Yan Z. Activation of 5-HT2A/ C receptors counteracts 5-HT1A regulation of n-methyl-D-aspartate receptor channels in pyramidal neurons of prefrontal cortex. J Biol Chem. 2008 ; 283 (25). 17194-17204.
    • (2008) J Biol Chem , vol.283 , Issue.25 , pp. 17194-17204
    • Yuen, E.Y.1    Jiang, Q.2    Chen, P.3    Feng, J.4    Yan, Z.5
  • 58
    • 0027164360 scopus 로고
    • Loss of brain 5-HT2 receptors in Alzheimer's disease. in vivo assessment with positron emission tomography and [18F]setoperone
    • Blin J., Baron JC, Dubois B., et al. Loss of brain 5-HT2 receptors in Alzheimer's disease. In vivo assessment with positron emission tomography and [18F]setoperone. Brain. 1993 ; 116 (pt 3). 497-510.
    • (1993) Brain , vol.116 , Issue.3 , pp. 497-510
    • Blin, J.1    Baron, J.C.2    Dubois, B.3
  • 59
    • 53649098483 scopus 로고    scopus 로고
    • Reduced 5-HT2A receptor binding in patients with mild cognitive impairment
    • Hasselbalch SG, Madsen K., Svarer C., et al. Reduced 5-HT2A receptor binding in patients with mild cognitive impairment. Neurobiol Aging. 2008 ; 29 (12). 1830-1838.
    • (2008) Neurobiol Aging , vol.29 , Issue.12 , pp. 1830-1838
    • Hasselbalch, S.G.1    Madsen, K.2    Svarer, C.3
  • 60
    • 43049094805 scopus 로고    scopus 로고
    • Imbalance of a serotonergic system in frontotemporal dementia: Implication for pharmacotherapy
    • Berl).
    • Bowen DM, Procter AW, Mann DM, et al. Imbalance of a serotonergic system in frontotemporal dementia: implication for pharmacotherapy. Psychopharmacology (Berl). 2008 ; 196 (4). 603-610.
    • (2008) Psychopharmacology , vol.196 , Issue.4 , pp. 603-610
    • Bowen, D.M.1    Procter, A.W.2    Mann, D.M.3
  • 61
    • 18744402189 scopus 로고    scopus 로고
    • Loss of serotonin 5-HT2A receptors in the postmortem temporal cortex correlates with rate of cognitive decline in Alzheimer's disease
    • Berl).
    • Lai MK, Tsang SW, Alder JT, et al. Loss of serotonin 5-HT2A receptors in the postmortem temporal cortex correlates with rate of cognitive decline in Alzheimer's disease. Psychopharmacology (Berl). 2005 ; 179 (3). 673-677.
    • (2005) Psychopharmacology , vol.179 , Issue.3 , pp. 673-677
    • Lai, M.K.1    Tsang, S.W.2    Alder, J.T.3
  • 62
    • 0030780254 scopus 로고    scopus 로고
    • The IRS-signaling system: A network of docking proteins that mediate insulin and cytokine action
    • White MF, Yenush L. The IRS-signaling system: a network of docking proteins that mediate insulin and cytokine action. Curr Top Microbiol Immunol. 1998 ; 228: 179-208.
    • (1998) Curr Top Microbiol Immunol , vol.228 , pp. 179-208
    • White, M.F.1    Yenush, L.2
  • 63
    • 0033197996 scopus 로고    scopus 로고
    • The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses
    • Abbott MA, Wells DG, Fallon JR The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses. J Neurosci. 1999 ; 19 (17). 7300-7308.
    • (1999) J Neurosci , vol.19 , Issue.17 , pp. 7300-7308
    • Abbott, M.A.1    Wells, D.G.2    Fallon, J.R.3
  • 64
    • 60549084867 scopus 로고    scopus 로고
    • Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Abeta oligomers
    • De Felice FG, Vieira MN, Bomfim TR, et al. Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. Proc Natl Acad Sci U S A. 2009 ; 106 (6). 1971-1976.
    • (2009) Proc Natl Acad Sci U S A. , vol.106 , Issue.6 , pp. 1971-1976
    • De Felice, F.G.1    Vieira, M.N.2    Bomfim, T.R.3
  • 65
    • 12044254746 scopus 로고
    • Binding of human apolipoprotein e to synthetic amyloid beta peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
    • Strittmatter WJ, Weisgraber KH, Huang DY, et al. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci U S A. 1993 ; 90 (17). 8098-8102.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , Issue.17 , pp. 8098-8102
    • Strittmatter, W.J.1    Weisgraber, K.H.2    Huang, D.Y.3
  • 66
    • 34047272692 scopus 로고    scopus 로고
    • A high-density whole-genome association study reveals that apoE is the major susceptibility gene for sporadic late-onset Alzheimer's disease
    • Coon KD, Myers AJ, Craig DW, et al. A high-density whole-genome association study reveals that apoE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J Clin Psychiatry. 2007 ; 68 (4). 613-618.
    • (2007) J Clin Psychiatry , vol.68 , Issue.4 , pp. 613-618
    • Coon, K.D.1    Myers, A.J.2    Craig, D.W.3
  • 67
    • 33750333569 scopus 로고    scopus 로고
    • Reelin, lipoprotein receptors and synaptic plasticity
    • Herz J., Chen Y. Reelin, lipoprotein receptors and synaptic plasticity. Nat Rev Neurosci. 2006 ; 7 (11). 850-859.
    • (2006) Nat Rev Neurosci , vol.7 , Issue.11 , pp. 850-859
    • Herz, J.1    Chen, Y.2
  • 68
    • 16244405249 scopus 로고    scopus 로고
    • Multiple pathways of apolipoprotein e signaling in primary neurons
    • Hoe HS, Harris DC, Rebeck GW Multiple pathways of apolipoprotein E signaling in primary neurons. J Neurochem. 2005 ; 93 (1). 145-155.
    • (2005) J Neurochem , vol.93 , Issue.1 , pp. 145-155
    • Hoe, H.S.1    Harris, D.C.2    Rebeck, G.W.3
  • 69
    • 33645639317 scopus 로고    scopus 로고
    • Apolipoprotein e receptor 2 interactions with the N-methyl-D-aspartate receptor
    • Hoe HS, Pocivavsek A., Chakraborty G., et al. Apolipoprotein E receptor 2 interactions with the N-methyl-D-aspartate receptor. J Biol Chem. 2006 ; 281 (6). 3425-3431.
    • (2006) J Biol Chem , vol.281 , Issue.6 , pp. 3425-3431
    • Hoe, H.S.1    Pocivavsek, A.2    Chakraborty, G.3
  • 70
    • 0034682827 scopus 로고    scopus 로고
    • Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction
    • Gotthardt M., Trommsdorff M., Nevitt MF, et al. Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. J Biol Chem. 2000 ; 275 (33). 25616-25624.
    • (2000) J Biol Chem , vol.275 , Issue.33 , pp. 25616-25624
    • Gotthardt, M.1    Trommsdorff, M.2    Nevitt, M.F.3
  • 71
    • 4744352010 scopus 로고    scopus 로고
    • Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice
    • May P., Rohlmann A., Bock HH, et al. Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. Mol Cell Biol. 2004 ; 24 (20). 8872-8883.
    • (2004) Mol Cell Biol , vol.24 , Issue.20 , pp. 8872-8883
    • May, P.1    Rohlmann, A.2    Bock, H.H.3
  • 72
    • 11244262612 scopus 로고    scopus 로고
    • Ultrastructural localization of reelin in the cortex in post-mortem human brain
    • Roberts RC, Xu L., Roche JK, Kirkpatrick B. Ultrastructural localization of reelin in the cortex in post-mortem human brain. J Comp Neurol. 2005 ; 482 (3). 294-308.
    • (2005) J Comp Neurol , vol.482 , Issue.3 , pp. 294-308
    • Roberts, R.C.1    Xu, L.2    Roche, J.K.3    Kirkpatrick, B.4
  • 73
    • 33645783001 scopus 로고    scopus 로고
    • Reelin expression and glycosylation patterns are altered in Alzheimer's disease
    • Botella-Lopez A., Burgaya F., Gaván R., et al. Reelin expression and glycosylation patterns are altered in Alzheimer's disease. Proc Natl Acad Sci U S A. 2006 ; 103 (14). 5573-5578.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.14 , pp. 5573-5578
    • Botella-Lopez, A.1    Burgaya, F.2    Gaván, R.3
  • 74
    • 62649098662 scopus 로고    scopus 로고
    • Age-related accumulation of Reelin in amyloid-like deposits
    • Knuesel I., Nyffeler M., Mormde C., et al. Age-related accumulation of Reelin in amyloid-like deposits. Neurobiol Aging. 2009 ; 30 (5). 697-716.
    • (2009) Neurobiol Aging. , vol.30 , Issue.5 , pp. 697-716
    • Knuesel, I.1    Nyffeler, M.2    Mormde, C.3
  • 75
    • 67049167155 scopus 로고    scopus 로고
    • Interaction of reelin with amyloid precursor protein promotes neurite outgrowth
    • Hoe HS, Lee KJ, Carney RS, et al. Interaction of reelin with amyloid precursor protein promotes neurite outgrowth. J Neurosci. 2009 ; 29 (23). 7459-7473.
    • (2009) J Neurosci. , vol.29 , Issue.23 , pp. 7459-7473
    • Hoe, H.S.1    Lee, K.J.2    Carney, R.S.3
  • 76
    • 50849122319 scopus 로고    scopus 로고
    • Functional interactions of APP with the apoE receptor family
    • Hoe HS, Rebeck GW Functional interactions of APP with the apoE receptor family. J Neurochem. 2008 ; 106 (6). 2263-2271.
    • (2008) J Neurochem , vol.106 , Issue.6 , pp. 2263-2271
    • Hoe, H.S.1    Rebeck, G.W.2
  • 77
    • 0030608509 scopus 로고    scopus 로고
    • Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density
    • Wu K., Xu JL, Suen PC, et al. Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density. Brain Res Mol Brain Res. 1996 ; 43 (1-2). 286-290.
    • (1996) Brain Res Mol Brain Res , vol.43 , Issue.1-2 , pp. 286-290
    • Wu, K.1    Xu, J.L.2    Suen, P.C.3
  • 78
    • 13244279632 scopus 로고    scopus 로고
    • Cyclic AMP controls BDNFinduced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons
    • Ji Y., Pang PT, Feng L., Lu B. Cyclic AMP controls BDNFinduced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons. Nat Neurosci. 2005 ; 8 (2). 164-172.
    • (2005) Nat Neurosci , vol.8 , Issue.2 , pp. 164-172
    • Ji, Y.1    Pang, P.T.2    Feng, L.3    Lu, B.4
  • 79
    • 62049083420 scopus 로고    scopus 로고
    • Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease
    • 2009;
    • Nagahara AH, Merrill DA, Coppola G., et al. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nat Med. 2 009; 15 (3). 331-337.
    • Nat Med , vol.15 , Issue.3 , pp. 331-337
    • Nagahara, A.H.1    Merrill, D.A.2    Coppola, G.3
  • 80
    • 63849151219 scopus 로고    scopus 로고
    • Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice
    • Simmons DA, Rex CS, Palmer L., et al. Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice. Proc Natl Acad Sci U S A. 2009 ; 106 (12). 4906-4911.
    • (2009) Proc Natl Acad Sci U S A. , vol.106 , Issue.12 , pp. 4906-4911
    • Simmons, D.A.1    Rex, C.S.2    Palmer, L.3
  • 81
    • 42249114000 scopus 로고    scopus 로고
    • MAGUK proteins: New targets for pharmacological intervention in the glutamatergic synapse
    • Gardoni F. MAGUK proteins: new targets for pharmacological intervention in the glutamatergic synapse. Eur J Pharmacol. 2008 ; 585 (1). 147-152.
    • (2008) Eur J Pharmacol , vol.585 , Issue.1 , pp. 147-152
    • Gardoni, F.1
  • 82
    • 33751216748 scopus 로고    scopus 로고
    • Differential expression of PSD proteins in age-related spatial learning impairments
    • Nyffeler M., Zhang WN, Feldon J., Knuesel I. Differential expression of PSD proteins in age-related spatial learning impairments. Neurobiol Aging. 2007 ; 28 (1). 143-155.
    • (2007) Neurobiol Aging , vol.28 , Issue.1 , pp. 143-155
    • Nyffeler, M.1    Zhang, W.N.2    Feldon, J.3    Knuesel, I.4
  • 83
    • 52449129626 scopus 로고    scopus 로고
    • Differential changes in synaptic proteins in the Alzheimer frontal cortex with marked increase in PSD-95 postsynaptic protein
    • Leuba G., Savioz A., Vernay A., et al. Differential changes in synaptic proteins in the Alzheimer frontal cortex with marked increase in PSD-95 postsynaptic protein. J Alzheimers Dis. 2008 ; 15 (1). 139-151.
    • (2008) J Alzheimers Dis , vol.15 , Issue.1 , pp. 139-151
    • Leuba, G.1    Savioz, A.2    Vernay, A.3
  • 84
    • 7244223228 scopus 로고    scopus 로고
    • Synaptic changes in Alzheimer's disease: Increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence
    • Gylys KH, Fein JA, Yang F., Wiley DJ, Miller CA, Cole GM Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence. Am J Pathol. 2004 ; 165 (5). 1809-1817.
    • (2004) Am J Pathol , vol.165 , Issue.5 , pp. 1809-1817
    • Gylys, K.H.1    Fein, J.A.2    Yang, F.3    Wiley, D.J.4    Miller, C.A.5    Cole, G.M.6
  • 85
    • 0033600913 scopus 로고    scopus 로고
    • PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain
    • Christopherson KS, Hillier BJ, Lim WA, Bredt DS PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain. J Biol Chem. 1999 ; 274 (39). 27467-27473.
    • (1999) J Biol Chem , vol.274 , Issue.39 , pp. 27467-27473
    • Christopherson, K.S.1    Hillier, B.J.2    Lim, W.A.3    Bredt, D.S.4
  • 86
    • 33845954467 scopus 로고    scopus 로고
    • PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating
    • Lin Y., Jover-Mengual T., Wong J., Bennett MV, Zukin RS PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating. Proc Natl Acad Sci U S A. 2006 ; 103 (52). 19902-19907.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.52 , pp. 19902-19907
    • Lin, Y.1    Jover-Mengual, T.2    Wong, J.3    Bennett, M.V.4    Zukin, R.S.5
  • 87
    • 34247237148 scopus 로고    scopus 로고
    • PSD-95 is required for activity-driven synapse stabilization
    • Ehrlich I., Klein M., Rumpel S., Malinow R. PSD-95 is required for activity-driven synapse stabilization. Proc Natl Acad Sci U S A. 2007 ; 104 (10). 4176-4181.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.10 , pp. 4176-4181
    • Ehrlich, I.1    Klein, M.2    Rumpel, S.3    Malinow, R.4
  • 88
    • 31544482776 scopus 로고    scopus 로고
    • An architectural framework that may lie at the core of the postsynaptic density
    • Baron MK, Boeckers TM, Vaida B., et al. An architectural framework that may lie at the core of the postsynaptic density. Science. 2006 ; 311 (5760). 531-535.
    • (2006) Science , vol.311 , Issue.5760 , pp. 531-535
    • Baron, M.K.1    Boeckers, T.M.2    Vaida, B.3
  • 89
    • 30644475475 scopus 로고    scopus 로고
    • Soluble beta-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses
    • Roselli F., Tirard M., Lu J., et al. Soluble beta-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses. J Neurosci. 2005 ; 25 (48). 11061-11070.
    • (2005) J Neurosci , vol.25 , Issue.48 , pp. 11061-11070
    • Roselli, F.1    Tirard, M.2    Lu, J.3
  • 90
    • 58149379613 scopus 로고    scopus 로고
    • SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin
    • Carlisle HJ, Manzerra P., Marcora E., Kennedy MB SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin. J Neurosci. 2008 ; 28 (50). 13673-13683.
    • (2008) J Neurosci , vol.28 , Issue.50 , pp. 13673-13683
    • Carlisle, H.J.1    Manzerra, P.2    Marcora, E.3    Kennedy, M.B.4
  • 91
    • 77953704732 scopus 로고    scopus 로고
    • Role of drebrin A in dendritic spine plasticity and synaptic function: Implications in neurological disorders
    • Ivanov A., Esclapez M., Ferhat L. Role of drebrin A in dendritic spine plasticity and synaptic function: implications in neurological disorders. Commun Integr Biol. 2009 ; 2 (3). 268-270.
    • (2009) Commun Integr Biol. , vol.2 , Issue.3 , pp. 268-270
    • Ivanov, A.1    Esclapez, M.2    Ferhat, L.3
  • 92
    • 65349085563 scopus 로고    scopus 로고
    • Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis
    • Hotulainen P., Llano O., Smirnov S., et al. Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis. J Cell Biol. 2009 ; 185 (2). 323-339.
    • (2009) J Cell Biol. , vol.185 , Issue.2 , pp. 323-339
    • Hotulainen, P.1    Llano, O.2    Smirnov, S.3
  • 93
    • 23044455322 scopus 로고    scopus 로고
    • Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses
    • Morishita W., Marie H., Malenka RC Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses. Nat Neurosci. 2005 ; 8 (8). 1043-1050.
    • (2005) Nat Neurosci , vol.8 , Issue.8 , pp. 1043-1050
    • Morishita, W.1    Marie, H.2    Malenka, R.C.3
  • 94
    • 11244313831 scopus 로고    scopus 로고
    • Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis
    • Lee-Hoeflich ST, Causing CG, Podkowa M., Zhao X., Wrana JL, Attisano L. Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis. EMBO J. 2004 ; 23 (24). 4792-4801.
    • (2004) EMBO J , vol.23 , Issue.24 , pp. 4792-4801
    • Lee-Hoeflich, S.T.1    Causing, C.G.2    Podkowa, M.3    Zhao, X.4    Wrana, J.L.5    Attisano, L.6
  • 95
    • 70450148316 scopus 로고    scopus 로고
    • Mapping cofilin-actin rods in stressed hippocampal slices and the role of cdc42 in amyloid-beta-induced rods
    • Davis RC, Maloney MT, Minamide LS, Flynn KC, Stonebraker MA, Bamburg JR Mapping cofilin-actin rods in stressed hippocampal slices and the role of cdc42 in amyloid-beta-induced rods. J Alzheimers Dis. 2009 ; 18 (1). 35-50.
    • (2009) J Alzheimers Dis. , vol.18 , Issue.1 , pp. 35-50
    • Davis, R.C.1    Maloney, M.T.2    Minamide, L.S.3    Flynn, K.C.4    Stonebraker, M.A.5    Bamburg, J.R.6
  • 96
    • 0036194258 scopus 로고    scopus 로고
    • Neurofilamentimmunoreactive neurons in Alzheimer's disease and dementia with Lewy bodies
    • Shepherd CE, McCann H., Thiel E., Halliday GM Neurofilamentimmunoreactive neurons in Alzheimer's disease and dementia with Lewy bodies. Neurobiol Dis. 2002 ; 9 (2). 249-257.
    • (2002) Neurobiol Dis , vol.9 , Issue.2 , pp. 249-257
    • Shepherd, C.E.1    McCann, H.2    Thiel, E.3    Halliday, G.M.4
  • 97
    • 0031035211 scopus 로고    scopus 로고
    • Criteria for Alzheimer's disease and the nosology of dementia with Lewy bodies
    • Hansen LA, Samuel W. Criteria for Alzheimer's disease and the nosology of dementia with Lewy bodies. Neurology. 1997 ; 48 (1). 126-132.
    • (1997) Neurology , vol.48 , Issue.1 , pp. 126-132
    • Hansen, L.A.1    Samuel, W.2
  • 98
    • 33846564563 scopus 로고    scopus 로고
    • Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin
    • Futai K., Kim MJ, Hashikawa T., Scheiffele P., Sheng M., Hayashi Y. Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin. Nat Neurosci. 2007 ; 10 (2). 186-195.
    • (2007) Nat Neurosci , vol.10 , Issue.2 , pp. 186-195
    • Futai, K.1    Kim, M.J.2    Hashikawa, T.3    Scheiffele, P.4    Sheng, M.5    Hayashi, Y.6
  • 99
    • 43649084798 scopus 로고    scopus 로고
    • Apolipoprotein E4 domain interaction: Synaptic and cognitive deficits in mice
    • Zhong N., Scearce-Levie K., Ramaswamy G., Weisgraber KH Apolipoprotein E4 domain interaction: synaptic and cognitive deficits in mice. Alzheimers Dement. 2008 ; 4 (3). 179-192.
    • (2008) Alzheimers Dement , vol.4 , Issue.3 , pp. 179-192
    • Zhong, N.1    Scearce-Levie, K.2    Ramaswamy, G.3    Weisgraber, K.H.4
  • 100
    • 33947164895 scopus 로고    scopus 로고
    • Focal adhesions regulate Abeta signaling and cell death in Alzheimer's disease
    • Caltagarone J., Jing Z., Bowser R. Focal adhesions regulate Abeta signaling and cell death in Alzheimer's disease. Biochim Biophys Acta. 2007 ; 1772 (4). 438-445.
    • (2007) Biochim Biophys Acta , vol.1772 , Issue.4 , pp. 438-445
    • Caltagarone, J.1    Jing, Z.2    Bowser, R.3
  • 102
    • 0037646469 scopus 로고    scopus 로고
    • RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling
    • Okabe T., Nakamura T., Nishimura YN, et al. RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling. J Biol Chem. 2003 ; 278 (11). 9920-9927.
    • (2003) J Biol Chem , vol.278 , Issue.11 , pp. 9920-9927
    • Okabe, T.1    Nakamura, T.2    Nishimura, Y.N.3
  • 103
    • 0030245731 scopus 로고    scopus 로고
    • A model for central synaptic junctional complex formation based on the differential adhesive specificities of the cadherins
    • Fannon AM, Colman DR A model for central synaptic junctional complex formation based on the differential adhesive specificities of the cadherins. Neuron. 1996 ; 17 (3). 423-434.
    • (1996) Neuron , vol.17 , Issue.3 , pp. 423-434
    • Fannon, A.M.1    Colman, D.R.2
  • 104
    • 0032171372 scopus 로고    scopus 로고
    • N-cadherin redistribution during synaptogenesis in hippocampal neurons
    • Benson DL, Tanaka H. N-cadherin redistribution during synaptogenesis in hippocampal neurons. J Neurosci. 1998 ; 18 (17). 6892-6904.
    • (1998) J Neurosci , vol.18 , Issue.17 , pp. 6892-6904
    • Benson, D.L.1    Tanaka, H.2
  • 105
    • 34547909617 scopus 로고    scopus 로고
    • Synaptic anchorage of AMPA receptors by cadherins through neural plakophilin-related arm protein AMPA receptor-binding protein complexes
    • Silverman JB, Restituito S., Lu W., Lee-Edwards L., Khatri L., Ziff EB Synaptic anchorage of AMPA receptors by cadherins through neural plakophilin-related arm protein AMPA receptor-binding protein complexes. J Neurosci. 2007 ; 27 (32). 8505-8516.
    • (2007) J Neurosci , vol.27 , Issue.32 , pp. 8505-8516
    • Silverman, J.B.1    Restituito, S.2    Lu, W.3    Lee-Edwards, L.4    Khatri, L.5    Ziff, E.B.6
  • 106
    • 0141429160 scopus 로고    scopus 로고
    • ACBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations
    • Marambaud P., Wen PH, Dutt A., et al. ACBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. Cell. 2003 ; 114 (5). 635-645.
    • (2003) Cell , vol.114 , Issue.5 , pp. 635-645
    • Marambaud, P.1    Wen, P.H.2    Dutt, A.3
  • 107
    • 33744899335 scopus 로고    scopus 로고
    • Characterization of sequential N-cadherin cleavage by ADAM10 and PS1
    • Uemura K., Kihara T., Kuzuya A., et al. Characterization of sequential N-cadherin cleavage by ADAM10 and PS1. Neurosci Lett. 2006 ; 402 (3). 278-283.
    • (2006) Neurosci Lett , vol.402 , Issue.3 , pp. 278-283
    • Uemura, K.1    Kihara, T.2    Kuzuya, A.3
  • 108
    • 27744531603 scopus 로고    scopus 로고
    • Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability
    • Serban G., Kouchi Z., Baki L., et al. Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability. J Biol Chem. 2005 ; 280 (43). 36007-36012.
    • (2005) J Biol Chem , vol.280 , Issue.43 , pp. 36007-36012
    • Serban, G.1    Kouchi, Z.2    Baki, L.3
  • 109
    • 68949145839 scopus 로고    scopus 로고
    • Early changes in hippocampal eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease
    • Simn AM, de Maturana RL, Ricobaraza A., et al. Early changes in hippocampal eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease. J Alzheimers Dis. 2009 ; 17 (4). 773-786.
    • (2009) J Alzheimers Dis. , vol.17 , Issue.4 , pp. 773-786
    • Simn, A.M.1    De Maturana, R.L.2    Ricobaraza, A.3
  • 110
    • 0027447602 scopus 로고
    • The protein tyrosine kinase, fyn, in Alzheimer's disease pathology
    • Shirazi SK, Wood JG The protein tyrosine kinase, fyn, in Alzheimer's disease pathology. Neuroreport. 1993 ; 4 (4). 435-437.
    • (1993) Neuroreport , vol.4 , Issue.4 , pp. 435-437
    • Shirazi, S.K.1    Wood, J.G.2
  • 111
    • 0031046463 scopus 로고    scopus 로고
    • Protein kinase C and calcium/calmodulin-dependent protein kinase II phosphorylate three-repeat and four-repeat tau isoforms at different rates
    • Singh TJ, Grundke-Iqbal I., Wu WQ, et al. Protein kinase C and calcium/calmodulin-dependent protein kinase II phosphorylate three-repeat and four-repeat tau isoforms at different rates. Mol Cell Biochem. 1997 ; 168 (1-2). 141-148.
    • (1997) Mol Cell Biochem , vol.168 , Issue.1-2 , pp. 141-148
    • Singh, T.J.1    Grundke-Iqbal, I.2    Wu, W.Q.3
  • 112
    • 34250771556 scopus 로고    scopus 로고
    • The aging brain, a key target for the future: The protein kinase C involvement
    • Pascale A., Amadio M., Govoni S., Battaini F. The aging brain, a key target for the future: the protein kinase C involvement. Pharmacol Res. 2007 ; 55 (6). 560-569.
    • (2007) Pharmacol Res , vol.55 , Issue.6 , pp. 560-569
    • Pascale, A.1    Amadio, M.2    Govoni, S.3    Battaini, F.4
  • 113
    • 46649100113 scopus 로고    scopus 로고
    • P21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesis
    • Ma QL, Yang F., Calon F., et al. p21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesis. J Biol Chem. 2008 ; 283 (20). 14132-14143.
    • (2008) J Biol Chem , vol.283 , Issue.20 , pp. 14132-14143
    • Ma, Q.L.1    Yang, F.2    Calon, F.3
  • 114
  • 115
    • 77249158836 scopus 로고    scopus 로고
    • Beta-Amyloid induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation
    • Wu HY, Hudry E., Hashimoto T., et al. Beta-Amyloid induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation. J Neurosci. 2010 ; 30 (7). 2636-2649.
    • (2010) J Neurosci. , vol.30 , Issue.7 , pp. 2636-2649
    • Wu, H.Y.1    Hudry, E.2    Hashimoto, T.3
  • 116
    • 77951246736 scopus 로고    scopus 로고
    • Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy- 5-methyl-4-isoxazolepropionic Acid (AMPA) receptors prevents beta-amyloid oligomer-induced synaptic disruption
    • Zhao WQ, Santini F., Breese R., et al. Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) receptors prevents beta-amyloid oligomer-induced synaptic disruption. J Biol Chem. 2010 ; 285 (10). 7619-7632.
    • (2010) J Biol Chem. , vol.285 , Issue.10 , pp. 7619-7632
    • Zhao, W.Q.1    Santini, F.2    Breese, R.3
  • 118
    • 33846212717 scopus 로고    scopus 로고
    • Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration
    • Wang JZ, Grundke-Iqbal I., Iqbal K. Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration. Eur J Neurosci. 2007 ; 25 (1). 59-68.
    • (2007) Eur J Neurosci , vol.25 , Issue.1 , pp. 59-68
    • Wang, J.Z.1    Grundke-Iqbal, I.2    Iqbal, K.3
  • 119
    • 23944448182 scopus 로고    scopus 로고
    • Association of neuronal nitric oxide synthase C276T polymorphism with Alzheimer's disease
    • Galimberti D., Venturelli E., Gatti A., et al. Association of neuronal nitric oxide synthase C276T polymorphism with Alzheimer's disease. J Neurol. 2005 ; 252 (8). 985-986.
    • (2005) J Neurol , vol.252 , Issue.8 , pp. 985-986
    • Galimberti, D.1    Venturelli, E.2    Gatti, A.3
  • 120
    • 67650072530 scopus 로고    scopus 로고
    • Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease
    • Liu F., Shi J., Tanimukai H., et al. Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease. Brain. 2009 ; 132 (pt 7). 1820-1832.
    • (2009) Brain. , vol.132 , Issue.7 , pp. 1820-1832
    • Liu, F.1    Shi, J.2    Tanimukai, H.3
  • 121
    • 35448945269 scopus 로고    scopus 로고
    • The prolyl isomerase PIN1: A pivotal new twist in phosphorylation signalling and disease
    • Lu KP, Zhou XZ The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease. Nat Rev Mol Cell Biol. 2007 ; 8 (11). 904-916.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.11 , pp. 904-916
    • Lu, K.P.1    Zhou, X.Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.