An architectural framework that may lie at the core of the postsynaptic density

Science

Volumn 311, Issue 5760, 2006, Pages 531-535

  Baron, Marisa K ^a   Boeckers, Tobias M ^b   Vaida, Bianca ^b   Faham, Salem ^a   Gingery, Mari ^a   Sawaya, Michael R ^a   Salyer, Danielle ^a   Gundelfinger, Eckart D ^c   Bowie, James U ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ULM   (Germany)

^c LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; COMPLEXATION; CYTOLOGY;

HELICAL FIBERS; NEUROTRANSMITTER RECEPTORS; THE POSTSYNAPTIC DENSITY (PSD);

PROTEINS;

POSTSYNAPTIC DENSITY PROTEIN 95;

NEUROLOGY;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; EUKARYOTIC CELL; NEUROTRANSMITTER RELEASE; POSTSYNAPTIC INHIBITION; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PROTEIN MOTIF;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING SITES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HIPPOCAMPUS; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MUTATION; NEURONS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RATS; RECOMBINANT FUSION PROTEINS; SOLUBILITY; SYNAPSES; ZINC;

EUKARYOTA;

EID: 31544482776     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1118995     Document Type: Article

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36. Coordinates have been deposited in the Protein Data Bank with accession codes 2F3N and 2F44. This work was supported by NIH grant no. RO1 CA081000 to J.U.B., an NIH Cellular and Molecular Biology Training Grant to M.K.B., by the Deutsche Forschungsgemeinschaft (grants SFB 497/B8 and SFB 426/A1) to T.M.B. and E.D.G., and by the State of Baden-Württemberg (grant 1423/74) to T.M.B. J.U.B. is a Leukemia and Lymphoma Society Scholar.