β-amyloid and glutamate receptors

Experimental Neurology

Volumn 212, Issue 1, 2008, Pages 1-4

  Gasparini, Laura ^a   Dityatev, Alexander ^a  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; AMYLOID BETA PROTEIN; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ALZHEIMER DISEASE; ARTICLE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 44749089401     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2008.03.005     Document Type: Note

References (72)

1. Almeida C.G., Tampellini D., Takahashi R.H., Greengard P., Lin M.T., Snyder E.M., and Gouras G.K. Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses. Neurobiol. Dis. 20 (2005) 187-198
2. Aronica E.M., Gorter J.A., Paupard M.C., Grooms S.Y., Bennett M.V., and Zukin R.S. Status epilepticus-induced alterations in metabotropic glutamate receptor expression in young and adult rats. J. Neurosci. 17 (1997) 8588-8595
3. Beattie E.C., Stellwagen D., Morishita W., Bresnahan J.C., Ha B.K., Von Zastrow M., Beattie M.S., and Malenka R.C. Control of synaptic strength by glial TNFalpha. Science 295 (2002) 2282-2285
4. Braithwaite S.P., Paul S., Nairn A.C., and Lombroso P.J. Synaptic plasticity: one STEP at a time. Trends Neurosci. 29 (2006) 452-458
5. Cleary J.P., Lesne S., Reed M., Hofmeister J., and Ashe K.H. Cognitive effects of synthetic and neuron-derived soluble abeta oligomers. 2007 Neuroscience Meeting Planner, San Diego, CA: Society for Neuroscience (2007) Online Program No. 856.11.
6. Cleary J.P., Walsh D.M., Hofmeister J.J., Shankar G.M., Kuskowski M.A., Selkoe D.J., and Ashe K.H. Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function. Nat. Neurosci. 8 (2005) 79-84
7. Cleary J.P., Walsh D.M., Hofmeister J.J., Shankar G.M., Kuskowski M.A., Selkoe D.J., and Ashe K.H. Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function. Nat. Neurosci. 8 (2005) 79-84
8. Deshpande A., Glabe C., and Busciglio J. Synaptic activity modulates oligomeric beta-amyloid synaptic targeting. 2007 Neuroscience Meeting Planner, San Diego, CA: Society for Neuroscience (2008) Online Program No. 856.7.
9. Floden A.M., and Combs C.K. Beta-amyloid stimulates murine postnatal and adult microglia cultures in a unique manner. J. Neurosci. 26 (2006) 4644-4648
10. Gasparini L., Ongini E., Wilcock D., and Morgan D. Activity of flurbiprofen and chemically related anti-inflammatory drugs in models of Alzheimer's disease. Brain Res. Brain Res. Rev. 48 (2005) 400-408
11. Glenner G.G., and Wong C.W. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120 (1984) 885-890
12. Goate A., Chartier-Harlin M.C., Mullan M., Brown J., Crawford F., Fidani L., Giuffra L., Haynes A., Irving N., and James L. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349 (1991) 704-706
13. Goldgaber D., Lerman M.I., McBride O.W., Saffiotti U., and Gajdusek D.C. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science 235 (1987) 877-880
14. Gu Q.B., Zhao J.X., Fei J., and Schwarz W. Modulation of Na(+),K(+) pumping and neurotransmitter uptake by beta-amyloid. Neuroscience 126 (2004) 61-67
15. Hallett P.J., Spoelgen R., Hyman B.T., Standaert D.G., and Dunah A.W. Dopamine D1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking. J. Neurosci. 26 (2006) 4690-4700
16. Hammond M.S., Sims C., Parameshwaran K., Suppiramaniam V., Schachner M., and Dityatev A. Neural cell adhesion molecule-associated polysialic acid inhibits NR2B-containing N-methyl-d-aspartate receptors and prevents glutamate-induced cell death. J. Biol. Chem. 281 (2006) 34859-34869
17. Harkany T., Abraham I., Timmerman W., Laskay G., Toth B., Sasvari M., Konya C., Sebens J.B., Korf J., Nyakas C., Zarandi M., Soos K., Penke B., and Luiten P.G. Beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis. Eur. J. Neurosci. 12 (2000) 2735-2745
18. Honer W.G. Pathology of presynaptic proteins in Alzheimer's disease: more than simple loss of terminals. Neurobiol. Aging 24 (2003) 1047-1062
19. Hsia A.Y., Masliah E., McConlogue L., Yu G.Q., Tatsuno G., Hu K., Kholodenko D., Malenka R.C., Nicoll R.A., and Mucke L. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 3228-3233
20. Hsieh H., Boehm J., Sato C., Iwatsubo T., Tomita T., Sisodia S., and Malinow R. AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 52 (2006) 831-843
21. Ivanov A., Pellegrino C., Rama S., Dumalska I., Salyha Y., Ben Ari Y., and Medina I. Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons. J. Physiol. 572 (2006) 789-798
22. Janelsins M.C., Mastrangelo M.A., Oddo S., LaFerla F.M., Federoff H.J., and Bowers W.J. Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. J. Neuroinflamm. 2 (2005) 23
23. Ju W., Morishita W., Tsui J., Gaietta G., Deerinck T.J., Adams S.R., Garner C.C., Tsien R.Y., Ellisman M.H., and Malenka R.C. Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors. Nat. Neurosci. 7 (2004) 244-253
24. Kamenetz F., Tomita T., Hsieh H., Seabrook G., Borchelt D., Iwatsubo T., Sisodia S., and Malinow R. APP processing and synaptic function. Neuron 37 (2003) 925-937
25. Kang J., Lemaire H.G., Unterbeck A., Salbaum J.M., Masters C.L., Grzeschik K.H., Multhaup G., Beyreuther K., and Muller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325 (1987) 733-736
26. Kimberly W.T., LaVoie M.J., Ostaszewski B.L., Ye W., Wolfe M.S., and Selkoe D.J. Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 6382-6387
27. Kimberly W.T., Xia W., Rahmati T., Wolfe M.S., and Selkoe D.J. The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation. J. Biol. Chem. 275 (2000) 3173-3178
28. Klein W.L., Krafft G.A., and Finch C.E. Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?. Trends Neurosci. 24 (2001) 219-224
29. Lacor P.N., Buniel M.C., Chang L., Fernandez S.J., Gong Y., Viola K.L., Lambert M.P., Velasco P.T., Bigio E.H., Finch C.E., Krafft G.A., and Klein W.L. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J. Neurosci. 24 (2004) 10191-10200
30. Lacor P.N., Buniel M.C., Furlow P.W., Clemente A.S., Velasco P.T., Wood M., Viola K.L., and Klein W.L. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J. Neurosci. 27 (2007) 796-807
31. Lambert M.P., Barlow A.K., Chromy B.A., Edwards C., Freed R., Liosatos M., Morgan T.E., Rozovsky I., Trommer B., Viola K.L., Wals P., Zhang C., Finch C.E., Krafft G.A., and Klein W.L. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 6448-6453
32. Larson J., Lynch G., Games D., and Seubert P. Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice. Brain Res. 840 (1999) 23-35
33. Lesne S. Beta amyloid*56 disrupts memory by binding to NMDA receptors in the brain. 2007 Neuroscience Meeting Planner, San Diego, CA: Society for Neuroscience (2007) Online Program No. 6.6. Ref Type: Generic
34. Lesne S., Koh M.T., Kotilinek L., Kayed R., Glabe C.G., Yang A., Gallagher M., and Ashe K.H. A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440 (2006) 352-357
35. Levy-Lahad E., Wasco W., Poorkaj P., Romano D.M., Oshima J., Pettingell W.H., Yu C.E., Jondro P.D., Schmidt S.D., and Wang K. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269 (1995) 973-977
36. Li R., Yang L., Lindholm K., Konishi Y., Yue X., Hampel H., Zhang D., and Shen Y. Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death. J. Neurosci. 24 (2004) 1760-1771
37. Liu Y., Wong T.P., Aarts M., Rooyakkers A., Liu L., Lai T.W., Wu D.C., Lu J., Tymianski M., Craig A.M., and Wang Y.T. NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J. Neurosci. 27 (2007) 2846-2857
38. Masters C.L., Simms G., Weinman N.A., Multhaup G., McDonald B.L., and Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. U. S. A. 82 (1985) 4245-4249
39. Medeiros R., Prediger R.D., Passos G.F., Pandolfo P., Duarte F.S., Franco J.L., Dafre A.L., Di Giunta G., Figueiredo C.P., Takahashi R.N., Campos M.M., and Calixto J.B. Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein. J. Neurosci. 27 (2007) 5394-5404
40. Meyer-Luehmann M., Spires-Jones T.L., Prada C., Garcia-Alloza M., de Calignon A., Rozkalne A., Koenigsknecht-Talboo J., Holtzman D.M., Bacskai B.J., and Hyman B.T. Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease. Nature 451 (2008) 720-724
41. Mullan M., Crawford F., Axelman K., Houlden H., Lilius L., Winblad B., and Lannfelt L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nat. Genet. 1 (1992) 345-347
42. Palop J.J., Chin J., Bien-Ly N., Massaro C., Yeung B.Z., Yu G.Q., and Mucke L. Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice. J. Neurosci. 25 (2005) 9686-9693
43. Parameshwaran K., Sims C., Kanju P., Vaithianathan T., Shonesy B.C., Dhanasekaran M., Bahr B.A., and Suppiramaniam V. Amyloid beta-peptide Abeta(1-42) but not Abeta(1-40) attenuates synaptic AMPA receptor function. Synapse 61 (2007) 367-374
44. Parameshwaran K., Dhanasekaran M., and Suppiramaniam V. Amyloid beta peptides and glutamatergic synaptic dysregulation. Exp.Neurol. 210 (2008) 7-13
45. Paul S., Nairn A.C., Wang P., and Lombroso P.J. NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat. Neurosci. 6 (2003) 34-42
46. Pelkey K.A., Askalan R., Paul S., Kalia L.V., Nguyen T.H., Pitcher G.M., Salter M.W., and Lombroso P.J. Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation. Neuron 34 (2002) 127-138
47. Pellegrini-Giampietro D.E., Gorter J.A., Bennett M.V., and Zukin R.S. The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders. Trends Neurosci. 20 (1997) 464-470
48. Robakis N.K., Wisniewski H.M., Jenkins E.C., Devine-Gage E.A., Houck G.E., Yao X.L., Ramakrishna N., Wolfe G., Silverman W.P., and Brown W.T. Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome. Lancet 1 (1987) 384-385
49. Rogaev E.I., Sherrington R., Rogaeva E.A., Levesque G., Ikeda M., Liang Y., Chi H., Lin C., Holman K., and Tsuda T. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376 (1995) 775-778
50. Scheff S.W., and Price D.A. Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies. Neurobiol. Aging 24 (2003) 1029-1046
51. Schmidt, C., Lepsverdize, E., Chi, S.L., Das, A.M., Pizzo, S.V., Dityatev, A., Schachner, M., in press. Amyloid precursor protein and amyloid beta-peptide bind to ATP synthase and regulate its activity at the surface of neural cells. Mol. Psychiatry. doi:10.1038/sj.mp.4002077.
52. Shankar G.M., Bloodgood B.L., Townsend M., Walsh D.M., Selkoe D.J., and Sabatini B.L. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J. Neurosci. 27 (2007) 2866-2875
53. Sherrington R., Rogaev E.I., Liang Y., Rogaeva E.A., Levesque G., Ikeda M., Chi H., Lin C., Li G., and Holman K. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375 (1995) 754-760
54. Shimokawa N., Qiu C.H., Seki T., Dikic I., and Koibuchi N. Phosphorylation of JNK is involved in regulation of H(+)-induced c-Jun expression. Cell Signal. 16 (2004) 723-729
55. Snyder E.M., Nong Y., Almeida C.G., Paul S., Moran T., Choi E.Y., Nairn A.C., Salter M.W., Lombroso P.J., Gouras G.K., and Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nat. Neurosci. 8 (2005) 1051-1058
56. Song D.K., Im Y.B., Jung J.S., Cho J., Suh H.W., and Kim Y.H. Central beta-amyloid peptide-induced peripheral interleukin-6 responses in mice. J. Neurochem. 76 (2001) 1326-1335
57. Tanaka H., Grooms S.Y., Bennett M.V., and Zukin R.S. The AMPAR subunit GluR2: still front and center-stage. Brain Res. 886 (2000) 190-207
58. Tanzi R.E., and Bertram L. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 120 (2005) 545-555
59. Tanzi R.E., Gusella J.F., Watkins P.C., Bruns G.A., George-Hyslop P., Van Keuren M.L., Patterson D., Pagan S., Kurnit D.M., and Neve R.L. Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science 235 (1987) 880-884
60. Terry R.D., Masliah E., Salmon D.P., Butters N., DeTeresa R., Hill R., Hansen L.A., and Katzman R. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann. Neurol. 30 (1991) 572-580
61. Townsend M., Shankar G.M., Mehta T., Walsh D.M., and Selkoe D.J. Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers. J.Physiol 572 (2006) 477-492
62. Tozaki H., Matsumoto A., Kanno T., Nagai K., Nagata T., Yamamoto S., and Nishizaki T. The inhibitory and facilitatory actions of amyloid-beta peptides on nicotinic ACh receptors and AMPA receptors. Biochem. Biophys. Res. Commun. 294 (2002) 42-45
63. Velisek L. Extracellular acidosis and high levels of carbon dioxide suppress synaptic transmission and prevent the induction of long-term potentiation in the CA1 region of rat hippocampal slices. Hippocampus 8 (1998) 24-32
64. Venkitaramani D.V., Chin J., Netzer W.J., Gouras G.K., Lesne S., Malinow R., and Lombroso P.J. Beta-amyloid modulation of synaptic transmission and plasticity. J. Neurosci. 27 (2007) 11832-11837
65. Verdier Y., Zarandi M., and Penke B. Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease. J. Pept. Sci. 10 (2004) 229-248
66. Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., Rowan M.J., and Selkoe D.J. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416 (2002) 535-539
67. Walsh D.M., and Selkoe D.J. Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration. Protein Pept. Lett. 11 (2004) 213-228
68. Wang Q., Rowan M.J., and Anwyl R. Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide. J. Neurosci. 24 (2004) 6049-6056
69. Wang Q., Wu J., Rowan M.J., and Anwyl R. Beta-amyloid inhibition of long-term potentiation is mediated via tumor necrosis factor. Eur. J. Neurosci. 22 (2005) 2827-2832
70. Wolfe M.S., Xia W., Ostaszewski B.L., Diehl T.S., Kimberly W.T., and Selkoe D.J. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature 398 (1999) 513-517
71. Wyss-Coray T. Inflammation in Alzheimer disease: driving force, bystander or beneficial response?. Nat. Med. 12 (2006) 1005-1015
72. Zhao W.Q., De Felice F.G., Fernandez S., Chen H., Lambert M.P., Quon M.J., Krafft G.A., and Klein W.L. Amyloid beta oligomers induce impairment of neuronal insulin receptors. FASEB J. 22 (2008) 246-260