Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity

Journal of Experimental Medicine

Volumn 207, Issue 10, 2010, Pages 2225-2237

  Guo, Wenzhong ^a   Smith, Diana ^a,b   Aviszus, Katja ^a   Detanico, Thiago ^a   Heiser, Ryan A ^a   Wysocki, Lawrence J ^a,b  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; ARGININE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CELL DIFFERENTIATION; CODON; COMPLEMENTARITY DETERMINING REGION; EXPERIMENTAL MODEL; FEMALE; IMMUNOGLOBULIN GENE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERTANT; SOMATIC HYPERMUTATION; SOMATIC MUTATION; SYSTEMIC LUPUS ERYTHEMATOSUS;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, ANTINUCLEAR; ARGININE; B-LYMPHOCYTES; COMPLEMENTARITY DETERMINING REGIONS; DISEASE MODELS, ANIMAL; GENES, IMMUNOGLOBULIN; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; RECOMBINATION, GENETIC; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 77957729025     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20092712     Document Type: Article

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