The structural basis for DNA binding by an anti-DNA autoantibody

Molecular Immunology

Volumn 35, Issue 18, 1998, Pages 1207-1217

  Jang, Y J ^a   Sanford, D ^b   Chung, H Y ^c   Baek, S Y ^a   Stollar, B D ^b  

^a Ajou University School of Medicine   (South Korea)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Korea Cancer Center Hospital   (South Korea)

Author keywords

Anti DNA; Antigen binding site; Autoantibodies; Molecular modeling; MRL lpr; Single chain Fv; Site directed mutagenesis

Indexed keywords

DNA ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY 2C10; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPUTER MODEL; DNA STRUCTURE; GENE ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIBODY AFFINITY; AUTOANTIBODIES; BINDING SITES, ANTIBODY; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, INBRED MRL LPR; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED;

EID: 0032462766     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(98)00095-9     Document Type: Article

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