Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome

Arthritis and Rheumatism

Volumn 56, Issue 7, 2007, Pages 2392-2401

  Lambrianides, Anastasia ^a   Giles, Ian ^a   Ioannou, Yiannis ^a   Mason, Lesley ^a   Latchman, David S ^a   Manson, Jessica J ^a   Isenberg, David A ^a   Rahman, Anisur ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ; ANTIGEN; ARGININE; BETA2 GLYCOPROTEIN 1; CARDIOLIPIN; DOUBLE STRANDED DNA; HUMAN MONOCLONAL ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN LIGHT CHAIN; OVALBUMIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIBODY AFFINITY; ANTIGEN BINDING; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; CELL STRAIN COS7; CHO CELL; CONTROLLED STUDY; HUMAN; IMMUNOGLOBULIN GENE; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; SYSTEMIC LUPUS ERYTHEMATOSUS;

AMINO ACID SEQUENCE; ANTIPHOSPHOLIPID SYNDROME; ARGININE; BINDING SITES; DNA PRIMERS; GERM-LINE MUTATION; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; LUPUS ERYTHEMATOSUS, SYSTEMIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OVALBUMIN; REPRODUCIBILITY OF RESULTS;

EID: 34547405325     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.22743     Document Type: Article

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