메뉴 건너뛰기




Volumn 7, Issue 4, 2010, Pages 403-411

Alternative splicing and breast cancer

Author keywords

Breast; Cancer; Genetics; Metastasis; Splicing

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR 2; GENOMIC DNA; MESSENGER RNA; RNA POLYMERASE II; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 77957307409     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.7.4.12152     Document Type: Review
Times cited : (38)

References (132)
  • 2
    • 0037079003 scopus 로고    scopus 로고
    • Rules for making human tumor cells
    • Hahn WC, Weinberg RA. Rules for making human tumor cells. N Engl J Med 2002; 347:1593-603.
    • (2002) N Engl J Med , vol.347 , pp. 1593-1603
    • Hahn, W.C.1    Weinberg, R.A.2
  • 3
    • 68949211272 scopus 로고    scopus 로고
    • Distant metastasis: Not out of reach any more
    • Bertucci F, Birnbaum D. Distant metastasis: not out of reach any more. J Biol 2009; 8:28.
    • (2009) J Biol , vol.8 , pp. 28
    • Bertucci, F.1    Birnbaum, D.2
  • 4
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
    • DOI 10.1016/j.devcel.2008.05.009, PII S1534580708002098
    • Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 2008; 14:818-29. (Pubitemid 351757205)
    • (2008) Developmental Cell , vol.14 , Issue.6 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 5
    • 46949102805 scopus 로고    scopus 로고
    • Mechanisms of malignant progression
    • Weinberg RA. Mechanisms of malignant progression. Carcinogenesis 2008; 29:1092.
    • (2008) Carcinogenesis , vol.29 , pp. 1092
    • Weinberg, R.A.1
  • 6
    • 52149088558 scopus 로고    scopus 로고
    • Molecular mechanisms of metastasis
    • Weber GF. Molecular mechanisms of metastasis. Cancer Lett 2008; 270:181-90.
    • (2008) Cancer Lett , vol.270 , pp. 181-190
    • Weber, G.F.1
  • 7
    • 33745684527 scopus 로고    scopus 로고
    • Metastasis: A question of life or death
    • Mehlen P, Puisieux A. Metastasis: a question of life or death. Nat Rev Cancer 2006; 6:449-58.
    • (2006) Nat Rev Cancer , vol.6 , pp. 449-458
    • Mehlen, P.1    Puisieux, A.2
  • 8
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-messenger RNA splicing
    • DOI 10.1146/annurev.biochem.72.121801.161720
    • Black DL. Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem 2003; 72:291-336. (Pubitemid 36930448)
    • (2003) Annual Review of Biochemistry , vol.72 , pp. 291-336
    • Black, D.L.1
  • 9
    • 33746927884 scopus 로고    scopus 로고
    • The connection between splicing and cancer
    • Srebrow A, Kornblihtt AR. The connection between splicing and cancer. J Cell Sci 2006; 119:2635-41.
    • (2006) J Cell Sci , vol.119 , pp. 2635-2641
    • Srebrow, A.1    Kornblihtt, A.R.2
  • 10
    • 0036534129 scopus 로고    scopus 로고
    • Alternative splicing: Multiple control mechanisms and involvement in human disease
    • Caceres JF, Kornblihtt AR. Alternative splicing: multiple control mechanisms and involvement in human disease. Trends Genet 2002; 18:186-93.
    • (2002) Trends Genet , vol.18 , pp. 186-193
    • Caceres, J.F.1    Kornblihtt, A.R.2
  • 11
    • 0034256020 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing: The logic of combinatorial control
    • Smith CW, Valcarcel J. Alternative pre-mRNA splicing: the logic of combinatorial control. Trends Biochem Sci 2000; 25:381-8.
    • (2000) Trends Biochem Sci , vol.25 , pp. 381-388
    • Smith, C.W.1    Valcarcel, J.2
  • 12
    • 34347400412 scopus 로고    scopus 로고
    • A new advance in alternative splicing databases: From catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants
    • DOI 10.1186/1471-2105-8-180
    • de la Grange P, Dutertre M, Correa M, Auboeuf D. A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants. BMC Bioinformatics 2007; 8:180. (Pubitemid 47018646)
    • (2007) BMC Bioinformatics , vol.8 , pp. 180
    • De La Grange, P.1    Dutertre, M.2    Correa, M.3    Auboeuf, D.4
  • 13
    • 23044503321 scopus 로고    scopus 로고
    • FAST DB: A website resource for the study of the expression regulation of human gene products
    • DOI 10.1093/nar/gki738
    • de la Grange P, Dutertre M, Martin N, Auboeuf D. FAST DB: a website resource for the study of the expression regulation of human gene products. Nucleic Acids Res 2005; 33:4276-84. (Pubitemid 41487286)
    • (2005) Nucleic Acids Research , vol.33 , Issue.13 , pp. 4276-4284
    • De La Grange, P.1    Dutertre, M.2    Martin, N.3    Auboeuf, D.4
  • 15
    • 67349209837 scopus 로고    scopus 로고
    • AspAlt: A tool for inter-database, inter-genomic and user-specific comparative analysis of alternative transcription and alternative splicing in 46 eukaryotes
    • Bhasi A, Philip P, Sreedharan VT, Senapathy P. AspAlt: A tool for inter-database, inter-genomic and user-specific comparative analysis of alternative transcription and alternative splicing in 46 eukaryotes. Genomics 2009.
    • (2009) Genomics
    • Bhasi, A.1    Philip, P.2    Sreedharan, V.T.3    Senapathy, P.4
  • 16
    • 76649088636 scopus 로고    scopus 로고
    • Alternative splicing and biological heterogeneity in prostate cancer
    • Rajan P, Elliott DJ, Robson CN, Leung HY. Alternative splicing and biological heterogeneity in prostate cancer. Nat Rev Urol 2009; 6:454-60.
    • (2009) Nat Rev Urol , vol.6 , pp. 454-460
    • Rajan, P.1    Elliott, D.J.2    Robson, C.N.3    Leung, H.Y.4
  • 17
    • 67849087126 scopus 로고    scopus 로고
    • Alternative splicing in lung cancer
    • Pio R, Montuenga LM. Alternative splicing in lung cancer. J Thorac Oncol 2009; 4:674-8.
    • (2009) J Thorac Oncol , vol.4 , pp. 674-678
    • Pio, R.1    Montuenga, L.M.2
  • 18
    • 55549143293 scopus 로고    scopus 로고
    • The emerging role of splicing factors in cancer
    • Grosso AR, Martins S, Carmo-Fonseca M. The emerging role of splicing factors in cancer. EMBO Rep 2008; 9:1087-93.
    • (2008) EMBO Rep , vol.9 , pp. 1087-1093
    • Grosso, A.R.1    Martins, S.2    Carmo-Fonseca, M.3
  • 19
    • 42549100051 scopus 로고    scopus 로고
    • Alternative splicing and disease
    • Kim E, Goren A, Ast G. Alternative splicing and disease. RNA Biol 2008; 5:17-9.
    • (2008) RNA Biol , vol.5 , pp. 17-19
    • Kim, E.1    Goren, A.2    Ast, G.3
  • 20
    • 38449111154 scopus 로고    scopus 로고
    • Pre-mRNA splicing aberrations and cancer
    • Pettigrew CA, Brown MA. Pre-mRNA splicing aberrations and cancer. Front Biosci 2008; 13:1090-105.
    • (2008) Front Biosci , vol.13 , pp. 1090-1105
    • Pettigrew, C.A.1    Brown, M.A.2
  • 21
    • 64249084287 scopus 로고    scopus 로고
    • Aberrant RNA splicing and its functional consequences in cancer cells
    • Fackenthal JD, Godley LA. Aberrant RNA splicing and its functional consequences in cancer cells. Dis Model Mech 2008; 1:37-42.
    • (2008) Dis Model Mech , vol.1 , pp. 37-42
    • Fackenthal, J.D.1    Godley, L.A.2
  • 22
    • 33947541694 scopus 로고    scopus 로고
    • Alternative splicing: An emerging topic in molecular and clinical oncology
    • DOI 10.1016/S1470-2045(07)70104-3, PII S1470204507701043
    • Pajares MJ, Ezponda T, Catena R, Calvo A, Pio R, Montuenga LM. Alternative splicing: an emerging topic in molecular and clinical oncology. Lancet Oncol 2007; 8:349-57. (Pubitemid 46464532)
    • (2007) Lancet Oncology , vol.8 , Issue.4 , pp. 349-357
    • Pajares, M.J.1    Ezponda, T.2    Catena, R.3    Calvo, A.4    Pio, R.5    Montuenga, L.M.6
  • 23
    • 34447106755 scopus 로고    scopus 로고
    • Alternative splicing in cancer: Noise, functional or systematic?
    • Skotheim RI, Nees M. Alternative splicing in cancer: noise, functional or systematic? Int J Biochem Cell Biol 2007; 39:1432-49.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1432-1449
    • Skotheim, R.I.1    Nees, M.2
  • 24
    • 33645833000 scopus 로고    scopus 로고
    • Unbalanced alternative splicing and its significance in cancer
    • Venables JP. Unbalanced alternative splicing and its significance in cancer. Bioessays 2006; 28:378-86.
    • (2006) Bioessays , vol.28 , pp. 378-386
    • Venables, J.P.1
  • 25
    • 3042642783 scopus 로고    scopus 로고
    • Splice variants as cancer biomarkers
    • Brinkman BM. Splice variants as cancer biomarkers. Clin Biochem 2004; 37:584-94.
    • (2004) Clin Biochem , vol.37 , pp. 584-594
    • Brinkman, B.M.1
  • 27
    • 33846135109 scopus 로고    scopus 로고
    • MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development
    • DOI 10.1101/gad.1500707
    • Boutz PL, Chawla G, Stoilov P, Black DL. MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Genes Dev 2007; 21:71-84. (Pubitemid 46089709)
    • (2007) Genes and Development , vol.21 , Issue.1 , pp. 71-84
    • Boutz, P.L.1    Chawla, G.2    Stoilov, P.3    Black, D.L.4
  • 29
    • 21244439380 scopus 로고    scopus 로고
    • Regulation of apoptosis by alternative pre-mRNA splicing
    • DOI 10.1016/j.molcel.2005.05.026, PII S1097276505013754
    • Schwerk C, Schulze-Osthoff K. Regulation of apoptosis by alternative pre-mRNA splicing. Mol Cell 2005; 19:1-13. (Pubitemid 40884653)
    • (2005) Molecular Cell , vol.19 , Issue.1 , pp. 1-13
    • Schwerk, C.1    Schulze-Osthoff, K.2
  • 31
    • 33846186277 scopus 로고    scopus 로고
    • Association of p53 gene alterations with the expression of antiapoptotic survivin splice variants in breast cancer
    • DOI 10.1038/sj.onc.1209784, PII 1209784
    • Vegran F, Boidot R, Oudin C, Defrain C, Rebucci M, Lizard-Nacol S. Association of p53 gene alterations with the expression of antiapoptotic survivin splice variants in breast cancer. Oncogene 2007; 26:290-7. (Pubitemid 46095740)
    • (2007) Oncogene , vol.26 , Issue.2 , pp. 290-297
    • Vegran, F.1    Boidot, R.2    Oudin, C.3    Defrain, C.4    Rebucci, M.5    Lizard-Nacol, S.6
  • 32
    • 64749105982 scopus 로고    scopus 로고
    • Predictive value of survivin alternative transcript expression in locally advanced breast cancer patients treated with neoadjuvant chemotherapy
    • Boidot R, Vegran F, Lizard-Nacol S. Predictive value of survivin alternative transcript expression in locally advanced breast cancer patients treated with neoadjuvant chemotherapy. Int J Mol Med 2009; 23:285-91.
    • (2009) Int J Mol Med , vol.23 , pp. 285-291
    • Boidot, R.1    Vegran, F.2    Lizard-Nacol, S.3
  • 34
    • 75149150660 scopus 로고    scopus 로고
    • HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
    • David CJ, Chen M, Assanah M, Canoll P, Manley JL. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature; 463:364-8.
    • Nature , vol.463 , pp. 364-368
    • David, C.J.1    Chen, M.2    Assanah, M.3    Canoll, P.4    Manley, J.L.5
  • 35
    • 0034129125 scopus 로고    scopus 로고
    • The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo
    • Zhang HT, Scott PA, Morbidelli L, Peak S, Moore J, Turley H, et al. The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo. Br J Cancer 2000; 83:63-8.
    • (2000) Br J Cancer , vol.83 , pp. 63-68
    • Zhang, H.T.1    Scott, P.A.2    Morbidelli, L.3    Peak, S.4    Moore, J.5    Turley, H.6
  • 36
    • 54549123309 scopus 로고    scopus 로고
    • VEGF-A splicing: The key to anti-angiogenic therapeutics?
    • Harper SJ, Bates DO. VEGF-A splicing: the key to anti-angiogenic therapeutics? Nat Rev Cancer 2008; 8:880-7.
    • (2008) Nat Rev Cancer , vol.8 , pp. 880-887
    • Harper, S.J.1    Bates, D.O.2
  • 37
    • 2942511783 scopus 로고    scopus 로고
    • An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1
    • Elkin M, Orgel A, Kleinman HK. An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1. J Natl Cancer Inst 2004; 96:875-8.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 875-878
    • Elkin, M.1    Orgel, A.2    Kleinman, H.K.3
  • 38
    • 29144447982 scopus 로고    scopus 로고
    • Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene
    • Ghigna C, Giordano S, Shen H, Benvenuto F, Castiglioni F, Comoglio PM, et al. Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene. Mol Cell 2005; 20:881-90.
    • (2005) Mol Cell , vol.20 , pp. 881-890
    • Ghigna, C.1    Giordano, S.2    Shen, H.3    Benvenuto, F.4    Castiglioni, F.5    Comoglio, P.M.6
  • 39
    • 33745427597 scopus 로고    scopus 로고
    • Oncogenesis of RON receptor tyrosine kinase: A molecular target for malignant epithelial cancers
    • Wang MH, Yao HP, Zhou YQ. Oncogenesis of RON receptor tyrosine kinase: a molecular target for malignant epithelial cancers. Acta Pharmacol Sin 2006; 27:641-50.
    • (2006) Acta Pharmacol Sin , vol.27 , pp. 641-650
    • Wang, M.H.1    Yao, H.P.2    Zhou, Y.Q.3
  • 41
    • 33645743036 scopus 로고    scopus 로고
    • An osteopontin splice variant induces anchorage independence in human breast cancer cells
    • He B, Mirza M, Weber GF. An osteopontin splice variant induces anchorage independence in human breast cancer cells. Oncogene 2006; 25:2192-202.
    • (2006) Oncogene , vol.25 , pp. 2192-2202
    • He, B.1    Mirza, M.2    Weber, G.F.3
  • 42
    • 70350782482 scopus 로고    scopus 로고
    • Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways
    • Goncalves V, Matos P, Jordan P. Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways. Hum Mol Genet 2009; 18:3696-707.
    • (2009) Hum Mol Genet , vol.18 , pp. 3696-3707
    • Goncalves, V.1    Matos, P.2    Jordan, P.3
  • 44
    • 40949090037 scopus 로고    scopus 로고
    • Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis
    • Cha JY, Lambert QT, Reuther GW, Der CJ. Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis. Mol Cancer Res 2008; 6:435-45.
    • (2008) Mol Cancer Res , vol.6 , pp. 435-445
    • Cha, J.Y.1    Lambert, Q.T.2    Reuther, G.W.3    Der, C.J.4
  • 46
    • 9344222224 scopus 로고    scopus 로고
    • Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells
    • Moffa AB, Tannheimer SL, Ethier SP. Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells. Mol Cancer Res 2004; 2:643-52.
    • (2004) Mol Cancer Res , vol.2 , pp. 643-652
    • Moffa, A.B.1    Tannheimer, S.L.2    Ethier, S.P.3
  • 48
    • 61649087689 scopus 로고    scopus 로고
    • ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
    • Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP. ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell 2009; 33:591-601.
    • (2009) Mol Cell , vol.33 , pp. 591-601
    • Warzecha, C.C.1    Sato, T.K.2    Nabet, B.3    Hogenesch, J.B.4    Carstens, R.P.5
  • 49
    • 77950552549 scopus 로고    scopus 로고
    • The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events
    • Warzecha CC, Shen S, Xing Y, Carstens RP. The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events. RNA Biol 2009; 6:546-62.
    • (2009) RNA Biol , vol.6 , pp. 546-562
    • Warzecha, C.C.1    Shen, S.2    Xing, Y.3    Carstens, R.P.4
  • 50
    • 62749098351 scopus 로고    scopus 로고
    • A global view of cancer-specific transcript variants by subtractive transcriptome-wide analysis
    • He C, Zhou F, Zuo Z, Cheng H, Zhou R. A global view of cancer-specific transcript variants by subtractive transcriptome-wide analysis. PLoS One 2009; 4:4732.
    • (2009) PLoS One , vol.4 , pp. 4732
    • He, C.1    Zhou, F.2    Zuo, Z.3    Cheng, H.4    Zhou, R.5
  • 51
    • 37349089805 scopus 로고    scopus 로고
    • Insights into the connection between cancer and alternative splicing
    • DOI 10.1016/j.tig.2007.10.001, PII S0168952507003459
    • Kim E, Goren A, Ast G. Insights into the connection between cancer and alternative splicing. Trends Genet 2008; 24:7-10. (Pubitemid 350298628)
    • (2008) Trends in Genetics , vol.24 , Issue.1 , pp. 7-10
    • Kim, E.1    Goren, A.2    Ast, G.3
  • 52
    • 41849110528 scopus 로고    scopus 로고
    • Entropy measures quantify global splicing disorders in cancer
    • DOI 10.1371/journal.pcbi.1000011
    • Ritchie W, Granjeaud S, Puthier D, Gautheret D. Entropy measures quantify global splicing disorders in cancer. PLoS Comput Biol 2008; 4:1000011. (Pubitemid 351497526)
    • (2008) PLoS Computational Biology , vol.4 , Issue.3
    • Ritchie, W.1    Granjeaud, S.2    Puthier, D.3    Gautheret, D.4
  • 53
    • 36949013036 scopus 로고    scopus 로고
    • Genome-wide detection of testis- and testicular cancer-specific alternative splicing
    • DOI 10.1093/carcin/bgm194
    • He C, Zuo Z, Chen H, Zhang L, Zhou F, Cheng H, et al. Genome-wide detection of testis- and testicular cancer-specific alternative splicing. Carcinogenesis 2007; 28:2484-90. (Pubitemid 350238950)
    • (2007) Carcinogenesis , vol.28 , Issue.12 , pp. 2484-2490
    • He, C.1    Zuo, Z.2    Chen, H.3    Zhang, L.4    Zhou, F.5    Cheng, H.6    Zhou, R.7
  • 60
    • 33846467191 scopus 로고    scopus 로고
    • Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array
    • Gardina PJ, Clark TA, Shimada B, Staples MK, Yang Q, Veitch J, et al. Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array. BMC Genomics 2006; 7:325.
    • (2006) BMC Genomics , vol.7 , pp. 325
    • Gardina, P.J.1    Clark, T.A.2    Shimada, B.3    Staples, M.K.4    Yang, Q.5    Veitch, J.6
  • 62
    • 56649083778 scopus 로고    scopus 로고
    • Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer
    • Xi L, Feber A, Gupta V, Wu M, Bergemann AD, Landreneau RJ, et al. Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer. Nucleic Acids Res 2008; 36:6535-47.
    • (2008) Nucleic Acids Res , vol.36 , pp. 6535-6547
    • Xi, L.1    Feber, A.2    Gupta, V.3    Wu, M.4    Bergemann, A.D.5    Landreneau, R.J.6
  • 63
    • 63149156942 scopus 로고    scopus 로고
    • Exonic expression profiling of breast cancer and benign lesions: A retrospective analysis
    • Early Online Publication 2009
    • André F, Michiels S, Dessen P, Scott V, Suciu V, Uzan C, et al. Exonic expression profiling of breast cancer and benign lesions: a retrospective analysis. Lancet Oncol 2009; Early Online Publication 2009.
    • (2009) Lancet Oncol
    • André, F.1    Michiels, S.2    Dessen, P.3    Scott, V.4    Suciu, V.5    Uzan, C.6
  • 64
    • 0026503190 scopus 로고
    • Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor
    • Aslakson CJ, Miller FR. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res 1992; 52:1399-405.
    • (1992) Cancer Res , vol.52 , pp. 1399-1405
    • Aslakson, C.J.1    Miller, F.R.2
  • 65
    • 85011943080 scopus 로고    scopus 로고
    • Exon-Based Clustering of Murine Breast Tumor Transcriptomes Reveals Alternative Exons Whose Expression Is Associated with Metastasis
    • Dutertre M, Lacroix-Triki M, Driouch K, de la Grange P, Gratadou L, Beck S, et al. Exon-Based Clustering of Murine Breast Tumor Transcriptomes Reveals Alternative Exons Whose Expression Is Associated with Metastasis. Cancer Res.
    • Cancer Res
    • Dutertre, M.1    Lacroix-Triki, M.2    Driouch, K.3    De La Grange, P.4    Gratadou, L.5    Beck, S.6
  • 66
    • 19944432209 scopus 로고    scopus 로고
    • Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix
    • Eckhardt BL, Parker BS, van Laar RK, Restall CM, Natoli AL, Tavaria MD, et al. Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix. Mol Cancer Res 2005; 3:1-13.
    • (2005) Mol Cancer Res , vol.3 , pp. 1-13
    • Eckhardt, B.L.1    Parker, B.S.2    Van Laar, R.K.3    Restall, C.M.4    Natoli, A.L.5    Tavaria, M.D.6
  • 68
    • 33749149016 scopus 로고    scopus 로고
    • EASI - Enrichment of alternatively spliced isoforms
    • Venables JP, Burn J. EASI - enrichment of alternatively spliced isoforms. Nucleic Acids Res 2006; 34:103.
    • (2006) Nucleic Acids Res , vol.34 , pp. 103
    • Venables, J.P.1    Burn, J.2
  • 69
    • 56749098074 scopus 로고    scopus 로고
    • Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
    • Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat Genet 2008; 40:1413-5.
    • (2008) Nat Genet , vol.40 , pp. 1413-1415
    • Pan, Q.1    Shai, O.2    Lee, L.J.3    Frey, B.J.4    Blencowe, B.J.5
  • 71
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 72
    • 85011939346 scopus 로고    scopus 로고
    • Alternative splicing: Good and bad effects of translationally silent substitutions
    • Raponi M, Baralle D. Alternative splicing: good and bad effects of translationally silent substitutions. FEBS J.
    • FEBS J
    • Raponi, M.1    Baralle, D.2
  • 73
    • 15544379277 scopus 로고    scopus 로고
    • Are splicing mutations the most frequent cause of hereditary disease?
    • Lopez-Bigas N, Audit B, Ouzounis C, Parra G, Guigo R. Are splicing mutations the most frequent cause of hereditary disease? FEBS Lett 2005; 579:1900-3.
    • (2005) FEBS Lett , vol.579 , pp. 1900-1903
    • Lopez-Bigas, N.1    Audit, B.2    Ouzounis, C.3    Parra, G.4    Guigo, R.5
  • 74
    • 33745394130 scopus 로고    scopus 로고
    • Alternative splicing and RNA selection pressure - Evolutionary consequences for eukaryotic genomes
    • DOI 10.1038/nrg1896, PII N1896
    • Xing Y, Lee C. Alternative splicing and RNA selection pressure - evolutionary consequences for eukaryotic genomes. Nat Rev Genet 2006; 7:499-509. (Pubitemid 43943568)
    • (2006) Nature Reviews Genetics , vol.7 , Issue.7 , pp. 499-509
    • Xing, Y.1    Lee, C.2
  • 75
    • 63049108452 scopus 로고    scopus 로고
    • Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment
    • Venkitaraman AR. Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment. Annu Rev Pathol 2009; 4:461-87.
    • (2009) Annu Rev Pathol , vol.4 , pp. 461-487
    • Venkitaraman, A.R.1
  • 84
    • 0035158730 scopus 로고    scopus 로고
    • A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes
    • Liu HX, Cartegni L, Zhang MQ, Krainer AR. A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes. Nat Genet 2001; 27:55-8.
    • (2001) Nat Genet , vol.27 , pp. 55-58
    • Liu, H.X.1    Cartegni, L.2    Zhang, M.Q.3    Krainer, A.R.4
  • 85
    • 67449084504 scopus 로고    scopus 로고
    • Emerging roles of RNA and RNA-binding protein network in cancer cells
    • Kim MY, Hur J, Jeong S. Emerging roles of RNA and RNA-binding protein network in cancer cells. BMB Rep 2009; 42:125-30.
    • (2009) BMB Rep , vol.42 , pp. 125-130
    • Kim, M.Y.1    Hur, J.2    Jeong, S.3
  • 86
    • 63849148854 scopus 로고    scopus 로고
    • A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer
    • Reyal F, van Vliet MH, Armstrong NJ, Horlings HM, de Visser KE, Kok M, et al. A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer. Breast Cancer Res 2008; 10:93.
    • (2008) Breast Cancer Res , vol.10 , pp. 93
    • Reyal, F.1    Van Vliet, M.H.2    Armstrong, N.J.3    Horlings, H.M.4    De Visser, K.E.5    Kok, M.6
  • 87
    • 70349592843 scopus 로고    scopus 로고
    • A comprehensive in silico expression analysis of RNA binding proteins in normal and tumor tissue: Identification of potential players in tumor formation
    • Galante PA, Sandhu D, de Sousa Abreu R, Gradassi M, Slager N, et al. A comprehensive in silico expression analysis of RNA binding proteins in normal and tumor tissue: Identification of potential players in tumor formation. RNA Biol 2009; 6:426-33.
    • (2009) RNA Biol , vol.6 , pp. 426-433
    • Galante, P.A.1    Sandhu, D.2    De Sousa Abreu, R.3    Gradassi, M.4    Slager, N.5
  • 89
    • 33646426385 scopus 로고    scopus 로고
    • Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene
    • Watermann DO, Tang Y, Zur Hausen A, Jager M, Stamm S, Stickeler E. Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene. Cancer Res 2006; 66:4774-80.
    • (2006) Cancer Res , vol.66 , pp. 4774-4780
    • Watermann, D.O.1    Tang, Y.2    Zur Hausen, A.3    Jager, M.4    Stamm, S.5    Stickeler, E.6
  • 90
    • 0034924284 scopus 로고    scopus 로고
    • Differential expression of the early lung cancer detection marker, heterogeneous nuclear ribonucleoprotein-A2/B1 (hnRNP-A2/B1) in normal breast and neoplastic breast cancer
    • Zhou J, Allred DC, Avis I, Martinez A, Vos MD, Smith L, et al. Differential expression of the early lung cancer detection marker, heterogeneous nuclear ribonucleoprotein-A2/B1 (hnRNP-A2/B1) in normal breast and neoplastic breast cancer. Breast Cancer Res Treat 2001; 66:217-24.
    • (2001) Breast Cancer Res Treat , vol.66 , pp. 217-224
    • Zhou, J.1    Allred, D.C.2    Avis, I.3    Martinez, A.4    Vos, M.D.5    Smith, L.6
  • 93
    • 34547842168 scopus 로고    scopus 로고
    • Increased expression of SRp40 affecting CD44 splicing is associated with the clinical outcome of lymph node metastasis in human breast cancer
    • Huang CS, Shen CY, Wang HW, Wu PE, Cheng CW. Increased expression of SRp40 affecting CD44 splicing is associated with the clinical outcome of lymph node metastasis in human breast cancer. Clin Chim Acta 2007; 384:69-74.
    • (2007) Clin Chim Acta , vol.384 , pp. 69-74
    • Huang, C.S.1    Shen, C.Y.2    Wang, H.W.3    Wu, P.E.4    Cheng, C.W.5
  • 95
    • 34447297332 scopus 로고    scopus 로고
    • Cellular signals modulate alternative splicing
    • Tarn WY. Cellular signals modulate alternative splicing. J Biomed Sci 2007; 14:517-22.
    • (2007) J Biomed Sci , vol.14 , pp. 517-522
    • Tarn, W.Y.1
  • 96
    • 38349085591 scopus 로고    scopus 로고
    • Regulation of alternative splicing by reversible protein phosphorylation
    • Stamm S. Regulation of alternative splicing by reversible protein phosphorylation. J Biol Chem 2008; 283:1223-7.
    • (2008) J Biol Chem , vol.283 , pp. 1223-1227
    • Stamm, S.1
  • 97
    • 0036798006 scopus 로고    scopus 로고
    • Signals and their transduction pathways regulating alternative splicing: A new dimension of the human genome
    • Stamm S. Signals and their transduction pathways regulating alternative splicing: a new dimension of the human genome. Hum Mol Genet 2002; 11:2409-16. (Pubitemid 35174704)
    • (2002) Human Molecular Genetics , vol.11 , Issue.20 , pp. 2409-2416
    • Stamm, S.1
  • 98
    • 33947223157 scopus 로고    scopus 로고
    • Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic and pancreatic carcinomas
    • Hayes GM, Carrigan PE, Miller LJ. Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic and pancreatic carcinomas. Cancer Res 2007; 67:2072-80.
    • (2007) Cancer Res , vol.67 , pp. 2072-2080
    • Hayes, G.M.1    Carrigan, P.E.2    Miller, L.J.3
  • 99
    • 2142716979 scopus 로고    scopus 로고
    • The link between mRNA processing and transcription: Communication works both ways
    • Zorio DA, Bentley DL. The link between mRNA processing and transcription: communication works both ways. Exp Cell Res 2004; 296:91-7.
    • (2004) Exp Cell Res , vol.296 , pp. 91-97
    • Zorio, D.A.1    Bentley, D.L.2
  • 100
    • 70350569286 scopus 로고    scopus 로고
    • Mechanisms of alternative splicing regulation: Insights from molecular and genomics approaches
    • Chen M, Manley JL. Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat Rev Mol Cell Biol 2009; 10:741-54.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 741-754
    • Chen, M.1    Manley, J.L.2
  • 101
    • 33748351186 scopus 로고    scopus 로고
    • Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells
    • DOI 10.1038/nsmb1135, PII NSMB1135
    • Listerman I, Sapra AK, Neugebauer KM. Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells. Nat Struct Mol Biol 2006; 13:815-22. (Pubitemid 44338776)
    • (2006) Nature Structural and Molecular Biology , vol.13 , Issue.9 , pp. 815-822
    • Listerman, I.1    Sapra, A.K.2    Neugebauer, K.M.3
  • 102
    • 0029902511 scopus 로고    scopus 로고
    • The intranuclear site of excision of each intron in Balbiani ring 3 pre- MRNA is influenced by the time remaining to transcription termination and different excision efficiencies for the various introns
    • Wetterberg I, Bauren G, Wieslander L. The intranuclear site of excision of each intron in Balbiani ring 3 pre-mRNA is influenced by the time remaining to transcription termination and different excision efficiencies for the various introns. RNA 1996; 2:641-51. (Pubitemid 26374216)
    • (1996) RNA , vol.2 , Issue.7 , pp. 641-651
    • Wetterberg, I.1    Bauren, G.2    Wieslander, L.3
  • 103
    • 51349121081 scopus 로고    scopus 로고
    • Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes
    • Bittencourt D, Dutertre M, Sanchez G, Barbier J, Gratadou L, Auboeuf D. Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes. Mol Cell Biol 2008; 28:5811-24.
    • (2008) Mol Cell Biol , vol.28 , pp. 5811-5824
    • Bittencourt, D.1    Dutertre, M.2    Sanchez, G.3    Barbier, J.4    Gratadou, L.5    Auboeuf, D.6
  • 104
    • 0033834946 scopus 로고    scopus 로고
    • Coupled in vitro synthesis and splicing of RNA polymerase II transcripts
    • Ghosh S, Garcia-Blanco MA. Coupled in vitro synthesis and splicing of RNA polymerase II transcripts. RNA 2000; 6:1325-34.
    • (2000) RNA , vol.6 , pp. 1325-1334
    • Ghosh, S.1    Garcia-Blanco, M.A.2
  • 105
    • 33745132168 scopus 로고    scopus 로고
    • Functional coupling of RNAP II transcription to spliceosome assembly
    • Das R, Dufu K, Romney B, Feldt M, Elenko M, Reed R. Functional coupling of RNAP II transcription to spliceosome assembly. Genes Dev 2006; 20:1100-9.
    • (2006) Genes Dev , vol.20 , pp. 1100-1109
    • Das, R.1    Dufu, K.2    Romney, B.3    Feldt, M.4    Elenko, M.5    Reed, R.6
  • 110
    • 0037064150 scopus 로고    scopus 로고
    • Coordinate regulation of transcription and splicing by steroid receptor coregulators
    • DOI 10.1126/science.1073734
    • Auboeuf D, Honig A, Berget SM, O'Malley BW. Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science 2002; 298:416-9. (Pubitemid 35176350)
    • (2002) Science , vol.298 , Issue.5592 , pp. 416-419
    • Auboeuf, D.1    Honig, A.2    Berget, S.M.3    O'Malley, B.W.4
  • 111
    • 43149105398 scopus 로고    scopus 로고
    • Alteration of cyclin D1 transcript elongation by a mutated transcription factor upregulates the oncogenic D1b splice isoform in cancer
    • Sanchez G, Bittencourt D, Laud K, Barbier J, Delattre O, Auboeuf D, et al. Alteration of cyclin D1 transcript elongation by a mutated transcription factor upregulates the oncogenic D1b splice isoform in cancer. Proc Natl Acad Sci USA 2008; 105:6004-9.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6004-6009
    • Sanchez, G.1    Bittencourt, D.2    Laud, K.3    Barbier, J.4    Delattre, O.5    Auboeuf, D.6
  • 112
    • 48849100548 scopus 로고    scopus 로고
    • Coupled alteration of transcription and splicing by a single oncogene: Boosting the effect on cyclin D1 activity
    • Sanchez G, Delattre O, Auboeuf D, Dutertre M. Coupled alteration of transcription and splicing by a single oncogene: boosting the effect on cyclin D1 activity. Cell Cycle 2008; 7:2299-305.
    • (2008) Cell Cycle , vol.7 , pp. 2299-2305
    • Sanchez, G.1    Delattre, O.2    Auboeuf, D.3    Dutertre, M.4
  • 114
    • 69249104635 scopus 로고    scopus 로고
    • Playing inside the genes: Intragenic histone acetylation after membrane depolarization of neural cells opens a path for alternative splicing regulation
    • Schor IE, Kornblihtt AR. Playing inside the genes: Intragenic histone acetylation after membrane depolarization of neural cells opens a path for alternative splicing regulation. Commun Integr Biol 2009; 2:341-3.
    • (2009) Commun Integr Biol , vol.2 , pp. 341-343
    • Schor, I.E.1    Kornblihtt, A.R.2
  • 116
    • 69949132191 scopus 로고    scopus 로고
    • Chromatin organization marks exon-intron structure
    • Schwartz S, Meshorer E, Ast G. Chromatin organization marks exon-intron structure. Nat Struct Mol Biol 2009; 16:990-5.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 990-995
    • Schwartz, S.1    Meshorer, E.2    Ast, G.3
  • 117
    • 30044441988 scopus 로고    scopus 로고
    • The human SWI/SNF subunit Brm is a regulator of alternative splicing
    • Batsche E, Yaniv M, Muchardt C. The human SWI/SNF subunit Brm is a regulator of alternative splicing. Nat Struct Mol Biol 2006; 13:22-9.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 22-29
    • Batsche, E.1    Yaniv, M.2    Muchardt, C.3
  • 118
    • 62949123360 scopus 로고    scopus 로고
    • The role of KLF6 and its splice variants in cancer therapy
    • DiFeo A, Martignetti JA, Narla G. The role of KLF6 and its splice variants in cancer therapy. Drug Resist Updat 2009; 12:1-7.
    • (2009) Drug Resist Updat , vol.12 , pp. 1-7
    • DiFeo, A.1    Martignetti, J.A.2    Narla, G.3
  • 119
    • 74249100914 scopus 로고    scopus 로고
    • Fine-scale variation and genetic determinants of alternative splicing across individuals
    • Coulombe-Huntington J, Lam KC, Dias C, Majewski J. Fine-scale variation and genetic determinants of alternative splicing across individuals. PLoS Genet 2009; 5:1000766.
    • (2009) PLoS Genet , vol.5 , pp. 1000766
    • Coulombe-Huntington, J.1    Lam, K.C.2    Dias, C.3    Majewski, J.4
  • 121
    • 0003826861 scopus 로고    scopus 로고
    • Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides
    • Taylor JK, Zhang QQ, Wyatt JR, Dean NM. Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides. Nat Biotechnol 1999; 17:1097-100.
    • (1999) Nat Biotechnol , vol.17 , pp. 1097-1100
    • Taylor, J.K.1    Zhang, Q.Q.2    Wyatt, J.R.3    Dean, N.M.4
  • 122
    • 19544363571 scopus 로고    scopus 로고
    • Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements
    • DOI 10.1093/hmg/ddh272
    • Bruno IG, Jin W, Cote GJ. Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements. Hum Mol Genet 2004; 13:2409-20. (Pubitemid 39377845)
    • (2004) Human Molecular Genetics , vol.13 , Issue.20 , pp. 2409-2420
    • Bruno, I.G.1    Jin, W.2    Cote, G.J.3
  • 123
    • 0842347354 scopus 로고    scopus 로고
    • MDM2 and Its Splice Variant Messenger RNAs: Expression in Tumors and Down-Regulation Using Antisense Oligonucleotides
    • Bartel F, Harris LC, Wurl P, Taubert H. MDM2 and its splice variant messenger RNAs: expression in tumors and downregulation using antisense oligonucleotides. Mol Cancer Res 2004; 2:29-35. (Pubitemid 38167105)
    • (2004) Molecular Cancer Research , vol.2 , Issue.1 , pp. 29-35
    • Bartel, F.1    Harris, L.C.2    Wurl, P.3    Taubert, H.4
  • 124
    • 58149465910 scopus 로고    scopus 로고
    • Modification of HER2 pre-mRNA alternative splicing and its effects on breast cancer cells
    • Wan J, Sazani P, Kole R. Modification of HER2 pre-mRNA alternative splicing and its effects on breast cancer cells. Int J Cancer 2009; 124:772-7.
    • (2009) Int J Cancer , vol.124 , pp. 772-777
    • Wan, J.1    Sazani, P.2    Kole, R.3
  • 125
    • 33744811140 scopus 로고    scopus 로고
    • Tumor-targeting properties of novel antibodies specific to the large isoform of tenascin-C
    • DOI 10.1158/1078-0432.CCR-05-2804
    • Brack SS, Silacci M, Birchler M, Neri D. Tumortargeting properties of novel antibodies specific to the large isoform of tenascin-C. Clin Cancer Res 2006; 12:3200-8. (Pubitemid 43837370)
    • (2006) Clinical Cancer Research , vol.12 , Issue.10 , pp. 3200-3208
    • Brack, S.S.1    Silacci, M.2    Birchler, M.3    Neri, D.4
  • 129
    • 34547852903 scopus 로고    scopus 로고
    • SR proteins as potential targets for therapy
    • Soret J, Gabut M, Tazi J. SR proteins as potential targets for therapy. Prog Mol Subcell Biol 2006; 44:65-87.
    • (2006) Prog Mol Subcell Biol , vol.44 , pp. 65-87
    • Soret, J.1    Gabut, M.2    Tazi, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.