Alternative splicing microarrays reveal functional expression of neuron-specific regulators in Hodgkin lymphoma cells

Journal of Biological Chemistry

Volumn 280, Issue 6, 2005, Pages 4779-4784

  Relógio, Angela ^a   Ben Dov, Claudia ^b   Baum, Michael ^c   Ruggiu, Matteo ^d   Gemund, Christine ^a   Benes, Vladimir ^a   Darnell, Robert B ^d   Valcárcel, Juan ^b  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^c Febit Ag   (Germany)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DIAGNOSIS; DISEASE CONTROL; ENZYMES; NEUROLOGY; NUCLEIC ACIDS; TUMORS;

GENE EXPRESSIONS; GENE REGULATIONS; MICROARRAYS; OLIGONUCLEOTIDES;

GENETIC ENGINEERING;

MESSENGER RNA;

ALTERNATIVE RNA SPLICING; ARTICLE; DNA MICROARRAY; GENE CONTROL; HODGKIN DISEASE; HUMAN; HUMAN CELL; LYMPHOMA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROCESSING; RNA ISOLATION;

ALTERNATIVE SPLICING; BLOTTING, WESTERN; CELL LINE, TUMOR; CLUSTER ANALYSIS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DATABASES; DNA, COMPLEMENTARY; HODGKIN DISEASE; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 9; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 14244263334     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M411976200     Document Type: Article

References (35)

1. Butte, A (2002) Nat. Rev. Drug Discov. 12, 951-960
2. White, K. P., Rifkin, S. A., Hurban, P., and Hogness, D. S. (1999) Science 286, 2179-2184
3. Alizadeh, A. A., Eisen, M. B., Davis, R. E., Ma, C., Lossos, I. S., Rosenwald, A., Boldrick, J. C, Sabet, H., Tran, T., Yu, X., Powell, J. I., Yang, L., Marti, G. E., Moore, T., Hudson, J, Jr., Lu, L., Lewis, D. B., Tibshirani, R., Sherlock, G., Chan, W. C., Greiner, T. C., Weisenburger, D. D., Armitage, J. O., Warnke, R., Levy, R., Wilson, W., Grever, M. R., Byrd, J. C., Botstein, D., Brown, P. O., and Staudt, L. M. (2000) Nature 403, 503-511
4. Schwaenen, C., Wessendorf, S., Kestler, H. A., Dohner, H., Lichter, P., and Bentz, M. (2003) Ann. Hematol. 82, 323-332
5. Modrek, B., and Lee, C. (2002) Nat. Genet. 30, 13-19
6. Johnson, J. M., Castle, J., Garrett-Engele, P., Kan, Z., Loerch, P. M., Armour, C. D., Santos, R., Schadt, E. E., Stoughton, R., and Shoemaker, D. D. (2003) Science 302, 2141-2144
7. Brinkman, B. M. (2004) Clin. Biochem. 37, 584-594
8. Wang, H., Hubbell, E., Hu, J. S., Mei, G., Cline, M., Lu, G., Clark, T., Siani-Rose, M. A., Ares, M., Kulp, D. C., and Haussier, D. (2003) Bioinformatics (Oxf.) 19, Suppl. 1, i315-i1322
9. Lee, C., and Roy, M. (2004) Genome Biol. 5, 231
10. Shoemaker, D. D, Schadt, E. E., Armour, C. D., He, Y. D., Garrett-Engele, P., McDonagh, P. D., Loerch, P. M., Leonardson, A., Lum, P. Y., Cavet, G., Wu, L. F., Altschuler, S. J., Edwards, S., King, J., Tsang, J. S., Schimmack, G., Schelter, J. M., Koch, J., Ziman, M., Marton, M. J., Li, B., Cundiff, P., Ward, T., Castle, J., Krolewski, M., Meyer, M. R., Mao, M., Burchard, J., Kidd, M. J., Dai, H., Phillips, J. W., Linsley, P. S., Stoughton, R., Scherer, S., and Boguski, M. S. (2001) Nature 409, 922-927
11. Clark, T. A., Sugnet, C. W., and Ares, M., Jr. (2002) Science 296, 907-910
12. Yeakley, J. M., Fan, J. B., Doucet, D., Luo, L., Wickham, E., Ye, Z., Chee, M. S., and Fu, X. D. (2002) Nat Biotechnol., 20, 353-358
13. Smith, C. W. J., and Valcárcel, J., (2000) Trends Biochem. Sci, 25, 381-388
14. Black, D. L. (2000) Cell 103, 367-370
15. Caceres, J. F., and Kornblihtt, A. R. (2002) Trends Genet. 18, 186-193
16. Jensen, K. B., Dredge, B. K., Stefani, G., Zhong, R., Buckanovich, R. J., Okano, H. J., Yang, Y. Y., and Darnell, R. B. (2000) Neuron 25, 359-371
17. Ule, J., Jensen, K. B., Ruggiu, M., Mele, A., Ule, A., and Darnell, R. B. (2003) Science 302, 1212-1215
18. Kuppers, R., Klein, U., Schwering, I., Distler, V., Brauninger, A., Cattoretti, G., Tu, Y., Stolovitzky, G. A., Califano, A., Hansmann, M. L., and Dalla-Favera, R. (2003) J. Clin. Investig. 111, 529-537
19. Schwering, I., Brauninger, A., Distler, V., Jesdinsky, J., Diehl, V., Hansmann, M. L., Rajewsky, K., and Kuppers, R. (2003) Mol Med. 9, 85-95
20. Baum, M., Bielau, S., Rittner, N., Schmid, K., Eggelbusch, K., Dahms, M., Schlauersbach, A., Tahedl, H., Beier, M., Guimil, R., Scheffler, M., Hermann, C., Funk, J. M., Wixmerten, A., Rebscher, H., Honig, M., Andreae, C., Buchner, D., Moschel, E., Glathe, A., Jager, E., Thom, M., Greil, A., Bestvater, F., Obermeier, F., Burgmaier, J., Thome, K., Weichert, S., Hein, S., Binnewies, T., Foitzik, V., Muller, M., Stahler, C. F., and Stahler, P. F. (2003) Nucleic Acids Res. 31, e151
21. Zhou, Y., and Abagyan, R. (2002) BMC Bioinformatics 3, 3
22. Relógio, A., Schwager, C., Richter, A., Ansorge, W., and Valcarcel, J. (2002) Nucleic Acids Res. 30, e51
23. Sherr, C. J. (2004) Cell 116, 235-246
24. Sturzenhofecker, B., Schlott, T., Quentin, T., Kube, D., Jung, W., and Trumper, L. (2003) Leuk. Lymphoma 44, 1587-1596
25. Gunthert, U., Hofmann, M., Rudy, W., Reber, S., Zoller, M., Haussmann, I., Matzku, S., Wenzel, A., Ponta, H., and Herrlich, P. (1991) Cell 65, 13-24
26. Buckanovich, R. J., Posner, J. B., and Darnell, R. B. (1993) Neuron 11, 657-672
27. Darnell, R. B. (2004) Arch. Neurol. 61, 30-32
28. Yang, Y. Y., Yin, G. L., and Darnell, R. B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13254-13259
29. Gupta, S., Barrett, T., Whitmarsh, A. J., Cavanagh, J., Sluss, H. K., Derijard, B., and Davis, R. J. (1996) EMBO J. 15, 2760-2770
30. Hanamura, A., Caceres, J. F., Mayeda, A., Franza, B. R., Jr., and Krainer, A. R. (1998) RNA (N. Y.) 4, 430-444
31. Stickeler, E., Kittrell, F., Medina, D., and Berget, S. M. (1999) Oncogene 18, 3574-3582
32. Wu, S., Romfo, C. M., Nilsen, T. W., and Green, M. R. (1999) Nature 402, 832-835
33. Wang, C., Chua, K., Seghezzi, W., Lees, E., Gozani, O., and Reed, R. (1998) Genes Dev. 12, 1409-1414
34. Kay, C. L., Davies-Jones, G, A., Singal, R., and Winfield, D. A. (1993) J. Neurol. Neurosurg. Psychiatry 56, 831-832
35. Leppa, S., and Bohmann, D. (1999) Oncogene 18, 6158-6162