-
1
-
-
33746772684
-
Simultaneous determination of sulforaphane and its major metabolites from biological matrices with liquid chromatography-tandem mass spectroscopy
-
Agrawal, S., Winnik, B., Buckley, B., Mi, L., Chung, F.L. and Cook, T.J. 2006. Simultaneous determination of sulforaphane and its major metabolites from biological matrices with liquid chromatography-tandem mass spectroscopy. J. Chromatogr. B Analyt. Technol. Biomed. Life. Sci. 840:99-107.
-
(2006)
J. Chromatogr. B Analyt. Technol. Biomed. Life. Sci.
, vol.840
, pp. 99-107
-
-
Agrawal, S.1
Winnik, B.2
Buckley, B.3
Mi, L.4
Chung, F.L.5
Cook, T.J.6
-
2
-
-
33751225931
-
Quantitative measurement of sulforaphane, iberin and their mercapturic acid pathway metabolites in human plasma and urine using liquid chromatography-tandem electrospray ionisation mass spectrometry
-
Al Janobi, A.A., Mithen, R.F., Gasper, A.V., Shaw, P.N., Middleton, R.J., Ortori, C.A. and Barrett, D.A. 2006. Quantitative measurement of sulforaphane, iberin and their mercapturic acid pathway metabolites in human plasma and urine using liquid chromatography-tandem electrospray ionisation mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 844:223-234.
-
(2006)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.844
, pp. 223-234
-
-
Al Janobi, A.A.1
Mithen, R.F.2
Gasper, A.V.3
Shaw, P.N.4
Middleton, R.J.5
Ortori, C.A.6
Barrett, D.A.7
-
3
-
-
0346888660
-
Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes
-
Bacon, J.R., Williamson, G., Garner, R.C., Lappin, G., Langouet, S. and Bao, Y. 2003. Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes. Carcinogenesis 24:1903-1911.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1903-1911
-
-
Bacon, J.R.1
Williamson, G.2
Garner, R.C.3
Lappin, G.4
Langouet, S.5
Bao, Y.6
-
4
-
-
0033369477
-
Potent induction of carcinogen defence enzymes with sulforaphane, a putative prostate cancer chemopreventive agent
-
Brooks, J.D. and Paton, V.G. 1999. Potent induction of carcinogen defence enzymes with sulforaphane, a putative prostate cancer chemopreventive agent. Prostate Cancer Prostatic. Dis. 2:S8.
-
(1999)
Prostate Cancer Prostatic. Dis.
, vol.2
-
-
Brooks, J.D.1
Paton, V.G.2
-
5
-
-
0034854057
-
Potent induction of phase 2 enzymes in human prostate cells by sulforaphane
-
Brooks, J.D., Paton, V.G. and Vidanes, G. 2001. Potent induction of phase 2 enzymes in human prostate cells by sulforaphane. Cancer Epidemiol. Biomarkers Prev. 10:949-954.
-
(2001)
Cancer Epidemiol. Biomarkers Prev.
, vol.10
, pp. 949-954
-
-
Brooks, J.D.1
Paton, V.G.2
Vidanes, G.3
-
6
-
-
0034525122
-
Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate
-
Chung, F.L., Conaway, C.C., Rao, C.V. and Reddy, B.S. 2000. Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate. Carcinogenesis 21:2287-2291.
-
(2000)
Carcinogenesis
, vol.21
, pp. 2287-2291
-
-
Chung, F.L.1
Conaway, C.C.2
Rao, C.V.3
Reddy, B.S.4
-
7
-
-
24944480252
-
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice
-
Conaway, C.C., Wang, C.X., Pittman, B., Yang, Y.M., Schwartz, J.E., Tian, D., Mclntee, E.J., Hecht, S.S. and Chung, F.L. 2005. Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. Cancer Res. 65:8548-8557.
-
(2005)
Cancer Res.
, vol.65
, pp. 8548-8557
-
-
Conaway, C.C.1
Wang, C.X.2
Pittman, B.3
Yang, Y.M.4
Schwartz, J.E.5
Tian, D.6
McLntee, E.J.7
Hecht, S.S.8
Chung, F.L.9
-
9
-
-
33746239394
-
Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts
-
Dinkova-Kostova, A.T., Jenkins, S.N., Fahey, J.W., Ye, L., Wehage, S.L., Liby, K.T., Stephenson, K.K., Wade, K.L. and Talalay, P. 2006. Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts. Cancer Lett. 240:243-252.
-
(2006)
Cancer Lett.
, vol.240
, pp. 243-252
-
-
Dinkova-Kostova, A.T.1
Jenkins, S.N.2
Fahey, J.W.3
Ye, L.4
Wehage, S.L.5
Liby, K.T.6
Stephenson, K.K.7
Wade, K.L.8
Talalay, P.9
-
10
-
-
34247473917
-
Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts
-
Dinkova-Kostova, A.T., Fahey, J.W., Wade, K.L., Jenkins, S.N., Shapiro, T.A., Fuchs, E.J., Kerns, M.L. and Talalay, P. 2007. Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts. Cancer Epidemiol. Biomarkers Prev. 16:847-851.
-
(2007)
Cancer Epidemiol. Biomarkers Prev.
, vol.16
, pp. 847-851
-
-
Dinkova-Kostova, A.T.1
Fahey, J.W.2
Wade, K.L.3
Jenkins, S.N.4
Shapiro, T.A.5
Fuchs, E.J.6
Kerns, M.L.7
Talalay, P.8
-
11
-
-
55949104371
-
Quantification of sulforaphane mercapturic acid pathway conjugates in human urine by high-performance liquid chromatography and isotope-dilution tandem mass spectrometry
-
Egner, P.A., Kensler, T.W., Chen, J.G., Gange, S.J., Groopman, J.D. and Friesen, M.D. 2008. Quantification of sulforaphane mercapturic acid pathway conjugates in human urine by high-performance liquid chromatography and isotope-dilution tandem mass spectrometry. Chem. Res. Toxicol. 21:1991-1996.
-
(2008)
Chem. Res. Toxicol.
, vol.21
, pp. 1991-1996
-
-
Egner, P.A.1
Kensler, T.W.2
Chen, J.G.3
Gange, S.J.4
Groopman, J.D.5
Friesen, M.D.6
-
12
-
-
0035808553
-
The chemical diversity and distribution of glucosinolates and isothiocyanates among plants
-
Fahey, J.W., Zalcmann, A.T. and Talalay, P. 2001. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. Phytochemistry 56:5-51.
-
(2001)
Phytochemistry
, vol.56
, pp. 5-51
-
-
Fahey, J.W.1
Zalcmann, A.T.2
Talalay, P.3
-
13
-
-
0030931522
-
Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens
-
Fahey, J.W., Zhang, Y. and Talalay, P. 1997 Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc. Natl. Acad. Sci. USA 94:10367-10372.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10367-10372
-
-
Fahey, J.W.1
Zhang, Y.2
Talalay, P.3
-
14
-
-
0037188518
-
Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[α]pyrene- induced stomach tumors
-
Fahey, J.W., Haristoy, X., Dolan, P.M., Kensler, T.W., Scholtus, I., Stephenson, K.K., Talalay, P. and Lozniewski, A. 2002 Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[α]pyrene- induced stomach tumors. Proc. Natl. Acad. Sci. USA 99:7610-7615.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7610-7615
-
-
Fahey, J.W.1
Haristoy, X.2
Dolan, P.M.3
Kensler, T.W.4
Scholtus, I.5
Stephenson, K.K.6
Talalay, P.7
Lozniewski, A.8
-
15
-
-
0029781794
-
Transcription regulation of rat glutathione S-transferase Ya subunit gene expression by chemopreventive agents
-
Fei, P., Matwyshyn, G.A., Rushmore, T.H. and Kong, A.N. 1996. Transcription regulation of rat glutathione S-transferase Ya subunit gene expression by chemopreventive agents. Pharm. Res. 13:1043-1048.
-
(1996)
Pharm. Res.
, vol.13
, pp. 1043-1048
-
-
Fei, P.1
Matwyshyn, G.A.2
Rushmore, T.H.3
Kong, A.N.4
-
16
-
-
54749147170
-
Polyamine metabolism and transforming growth factor-beta signaling are affected in Caco-2 cells by differentially cooked broccoli extracts
-
Furniss, C.S., Bennett, R.N., Bacon, J.R., LeGall, G. and Mithen, R.F. 2008 Polyamine metabolism and transforming growth factor-beta signaling are affected in Caco-2 cells by differentially cooked broccoli extracts. J. Nutr. 138:1840-1845.
-
(2008)
J. Nutr.
, vol.138
, pp. 1840-1845
-
-
Furniss, C.S.1
Bennett, R.N.2
Bacon, J.R.3
Legall, G.4
Mithen, R.F.5
-
17
-
-
33644688761
-
Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli
-
Gasper, A.V., Al-Janobi, A., Smith, J.A., Bacon, J.R., Fortun, P., Atherton, C., Taylor, M.A., Hawkey, C.J., Barrett, D.A. and Mithen, R.F. 2005. Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli. Am. J. Clin. Nutr. 82:1283-1291.
-
(2005)
Am. J. Clin. Nutr.
, vol.82
, pp. 1283-1291
-
-
Gasper, A.V.1
Al-Janobi, A.2
Smith, J.A.3
Bacon, J.R.4
Fortun, P.5
Atherton, C.6
Taylor, M.A.7
Hawkey, C.J.8
Barrett, D.A.9
Mithen, R.F.10
-
18
-
-
33745393451
-
Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion
-
Gills, J.J., Jeffery, E.H., Matusheski, N.V., Moon, R.C., Lantvit, D.D. and Pezzuto, J.M. 2006 Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion. Cancer Lett. 236:72-79.
-
(2006)
Cancer Lett.
, vol.236
, pp. 72-79
-
-
Gills, J.J.1
Jeffery, E.H.2
Matusheski, N.V.3
Moon, R.C.4
Lantvit, D.D.5
Pezzuto, J.M.6
-
19
-
-
33745218882
-
Biology and biochemistry of glucosinolates
-
Halkier, B.A. and Gershenzon, J. 2006 Biology and biochemistry of glucosinolates. Annu. Rev. Plant Biol. 57:303-333.
-
(2006)
Annu. Rev. Plant Biol.
, vol.57
, pp. 303-333
-
-
Halkier, B.A.1
Gershenzon, J.2
-
21
-
-
0035943597
-
Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms
-
Heiss, E., Herhaus, C., Klimo, K., Bartsch, H. and Gerhäuser, C. 2001. Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms. J. Biol. Chem. 276:32008-32015.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32008-32015
-
-
Heiss, E.1
Herhaus, C.2
Klimo, K.3
Bartsch, H.4
Gerhäuser, C.5
-
22
-
-
3042688047
-
In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat
-
Hu, R., Hebbar, V., Kim, B.R., Chen, C., Winnik, B., Buckley, B., Soteropoulos, P., Tolias, P., Hart, R.P. and Kong, A.N. 2004. In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat. J. Pharmacol. Exp. Ther. 310:263-721.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, pp. 263-721
-
-
Hu, R.1
Hebbar, V.2
Kim, B.R.3
Chen, C.4
Winnik, B.5
Buckley, B.6
Soteropoulos, P.7
Tolias, P.8
Hart, R.P.9
Kong, A.N.10
-
23
-
-
33749581701
-
Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable
-
Hu, R., Khor, T.O., Shen, G., Jeong, W.S., Hebbar, V., Chen, C., Xu, C., Reddy, B., Chada, K. and Kong, A.N. 2006. Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable. Carcinogenesis 27:2038-2046.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2038-2046
-
-
Hu, R.1
Khor, T.O.2
Shen, G.3
Jeong, W.S.4
Hebbar, V.5
Chen, C.6
Xu, C.7
Reddy, B.8
Chada, K.9
Kong, A.N.10
-
24
-
-
0037418625
-
Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers
-
Jiang, Z.Q., Chen, C., Yang, B., Hebbar, V. and Kong, A.N. 2003. Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers. Life Sci. 72:2243-2253.
-
(2003)
Life Sci.
, vol.72
, pp. 2243-2253
-
-
Jiang, Z.Q.1
Chen, C.2
Yang, B.3
Hebbar, V.4
Kong, A.N.5
-
25
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler, T.W., Wakabayashi, N. and Biswal, S. 2007. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 47:89-116.
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
26
-
-
28644450910
-
Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China
-
Kensler, T.W., Chen, J.G., Egner, P.A., Fahey, J.W., Jacobson, L.P., Stephenson, K.K., Ye, L., Coady, J.L., Wang, J.B., Wu, Y., Sun, Y., Zhang, Q.N., Zhang, B.C., Zhu, Y.R., Qian, G.S., Carmella, S.G., Hecht, S.S., Benning, L., Gange, S.J., Groopman, J.D. and Talalay, P. 2005. Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China. Cancer Epidemiol. Biomarkers. Prev. 14:2605-2613.
-
(2005)
Cancer Epidemiol. Biomarkers. Prev.
, vol.14
, pp. 2605-2613
-
-
Kensler, T.W.1
Chen, J.G.2
Egner, P.A.3
Fahey, J.W.4
Jacobson, L.P.5
Stephenson, K.K.6
Ye, L.7
Coady, J.L.8
Wang, J.B.9
Wu, Y.10
Sun, Y.11
Zhang, Q.N.12
Zhang, B.C.13
Zhu, Y.R.14
Qian, G.S.15
Carmella, S.G.16
Hecht, S.S.17
Benning, L.18
Gange, S.J.19
Groopman, J.D.20
Talalay, P.21
more..
-
27
-
-
35448991707
-
Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex
-
Kerns, M.L., DePianto, D., Dinkova-Kostova, A.T., Talalay, P. and Coulombe, P.A. 2007. Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex. Proc. Natl. Acad. Sci. USA 104:14460-14465.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 14460-14465
-
-
Kerns, M.L.1
Depianto, D.2
Dinkova-Kostova, A.T.3
Talalay, P.4
Coulombe, P.A.5
-
28
-
-
33846094115
-
Pharmacogenomics of cancer chemopreventive isothiocyanate compound sulforaphane in the intestinal polyps of ApcMin/+ mice
-
Khor, T.O., Hu, R., Shen, G., Jeong, W.S., Hebbar, V., Chen, C., Xu, C., Nair, S., Reddy, B., Chada, K. and Kong, A.N. 2006. Pharmacogenomics of cancer chemopreventive isothiocyanate compound sulforaphane in the intestinal polyps of ApcMin/+ mice. Biopharm. Drug Dispos. 27:407-420.
-
(2006)
Biopharm. Drug Dispos.
, vol.27
, pp. 407-420
-
-
Khor, T.O.1
Hu, R.2
Shen, G.3
Jeong, W.S.4
Hebbar, V.5
Chen, C.6
Xu, C.7
Nair, S.8
Reddy, B.9
Chada, K.10
Kong, A.N.11
-
29
-
-
42749088621
-
Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity: Role of dendritic cells
-
e7
-
Kim, H.J., Barajas, B., Wang, M. and Nel, A.E. 2008. Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity: Role of dendritic cells. J. Allergy Clin. Immunol. 121:1255-1261.e7.
-
(2008)
J. Allergy Clin. Immunol.
, vol.121
, pp. 1255-1261
-
-
Kim, H.J.1
Barajas, B.2
Wang, M.3
Nel, A.E.4
-
30
-
-
33748052967
-
Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species
-
Kobayashi, M. and Yamamoto, M. 2006. Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species. Adv. Enzyme Regul. 46:113-140.
-
(2006)
Adv. Enzyme Regul.
, vol.46
, pp. 113-140
-
-
Kobayashi, M.1
Yamamoto, M.2
-
31
-
-
0036040438
-
Brassica vegetables and prostate cancer risk: A review of the epidemiological evidence
-
Kristal, A.R. and Lampe, J.W. 2002. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr. Cancer 42:1-9.
-
(2002)
Nutr. Cancer
, vol.42
, pp. 1-9
-
-
Kristal, A.R.1
Lampe, J.W.2
-
32
-
-
33746701934
-
Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters
-
Kuroiwa, Y., Nishikawa, A., Kitamura, Y., Kanki, K., Ishii, Y., Umemura, T. and Hirose, M. 2006. Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters. Cancer Lett. 241:275-280.
-
(2006)
Cancer Lett.
, vol.241
, pp. 275-280
-
-
Kuroiwa, Y.1
Nishikawa, A.2
Kitamura, Y.3
Kanki, K.4
Ishii, Y.5
Umemura, T.6
Hirose, M.7
-
33
-
-
52949139019
-
Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway
-
Lin, W., Wu, R.T., Wu, T., Khor, T.O., Wang, H. and Kong, A.N. 2008. Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway. Biochem. Pharmacol. 76:967-973.
-
(2008)
Biochem. Pharmacol.
, vol.76
, pp. 967-973
-
-
Lin, W.1
Wu, R.T.2
Wu, T.3
Khor, T.O.4
Wang, H.5
Kong, A.N.6
-
34
-
-
0030852501
-
Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes
-
Mahéo, K., Morel, F., Langouët, S., Kramer, H., Le Ferrec, E., Ketterer, B. and Guillouzo, A. 1997. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res. 57:3649-3652.
-
(1997)
Cancer Res.
, vol.57
, pp. 3649-3652
-
-
Mahéo, K.1
Morel, F.2
Langouët, S.3
Kramer, H.4
Le Ferrec, E.5
Ketterer, B.6
Guillouzo, A.7
-
35
-
-
0035543010
-
Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile
-
Matusheski, N.V. and Jeffery, E.H. 2001. Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile. J. Agric. Food Chem. 49:5743-5749.
-
(2001)
J. Agric. Food Chem.
, vol.49
, pp. 5743-5749
-
-
Matusheski, N.V.1
Jeffery, E.H.2
-
36
-
-
2942614968
-
Heating decreases epithiospecifier protein activity and increases sulforaphane formation in broccoli
-
Matusheski, N.V., Juvik, J.A. and Jeffery, E.H. 2004. Heating decreases epithiospecifier protein activity and increases sulforaphane formation in broccoli. Phytochemistry 65:1273-1281.
-
(2004)
Phytochemistry
, vol.65
, pp. 1273-1281
-
-
Matusheski, N.V.1
Juvik, J.A.2
Jeffery, E.H.3
-
37
-
-
0035870298
-
The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes
-
McMahon, M., Itoh, K., Yamamoto, M., Chanas, S.A., Henderson, C.J., McLellan, L.I., Wolf, C.R., Cavin, C. and Hayes, J.D. 2001. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. Cancer Res. 61:3299-3307.
-
(2001)
Cancer Res.
, vol.61
, pp. 3299-3307
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Chanas, S.A.4
Henderson, C.J.5
McLellan, L.I.6
Wolf, C.R.7
Cavin, C.8
Hayes, J.D.9
-
38
-
-
0038025250
-
Development of isothiocyanate-enriched broccoli, and its enhanced ability to induce phase 2 detoxification enzymes in mammalian cells
-
Mithen, R., Faulkner, K., Magrath, R., Rose, P., Williamson, G. and Marquez, J. 2003. Development of isothiocyanate-enriched broccoli, and its enhanced ability to induce phase 2 detoxification enzymes in mammalian cells. Theor. Appl. Genet. 106:727-734.
-
(2003)
Theor. Appl. Genet.
, vol.106
, pp. 727-734
-
-
Mithen, R.1
Faulkner, K.2
Magrath, R.3
Rose, P.4
Williamson, G.5
Marquez, J.6
-
39
-
-
0030824718
-
The use of primary hepatocyte cultures for the evaluation of chemoprotective agents
-
Morel, F., Langouët, S., Mahéo, K. and Guillouzo, A. 1997. The use of primary hepatocyte cultures for the evaluation of chemoprotective agents. Cell. Biol. Toxicol. 13:323-329.
-
(1997)
Cell. Biol. Toxicol.
, vol.13
, pp. 323-329
-
-
Morel, F.1
Langouët, S.2
Mahéo, K.3
Guillouzo, A.4
-
40
-
-
7244253081
-
Nrf2-Keap1 defines a physiologically important stress defense mechanism
-
Motohashi, H. and Yamamoto, M. 2004. Nrf2-Keap1 defines a physiologically important stress defense mechanism. Trends Molec. Med. 10:549-557.
-
(2004)
Trends Molec. Med.
, vol.10
, pp. 549-557
-
-
Motohashi, H.1
Yamamoto, M.2
-
41
-
-
1842588301
-
Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: Comparison of allyl isothiocyanate with sulforaphane and related compounds
-
Munday, R. and Munday, C.M. 2004. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J. Agric. Food Chem. 52:1867-1871.
-
(2004)
J. Agric. Food Chem.
, vol.52
, pp. 1867-1871
-
-
Munday, R.1
Munday, C.M.2
-
42
-
-
40449129950
-
Inhibition of urinary bladder carcinogenesis by broccoli sprouts
-
Munday, R., Mhawech-Fauceglia, P., Munday, C.M., Paonessa, J.D., Tang, L., Munday, J.S., Lister, C., Wilson, P., Fahey, J.W., Davis, W. and Zhang, Y. 2008. Inhibition of urinary bladder carcinogenesis by broccoli sprouts. Cancer Res. 68:1593-1600.
-
(2008)
Cancer Res.
, vol.68
, pp. 1593-1600
-
-
Munday, R.1
Mhawech-Fauceglia, P.2
Munday, C.M.3
Paonessa, J.D.4
Tang, L.5
Munday, J.S.6
Lister, C.7
Wilson, P.8
Fahey, J.W.9
Davis, W.10
Zhang, Y.11
-
43
-
-
33645825587
-
min mice
-
Myzak, M.C., Dashwood, W.M., Orner, G.A., Ho, E. and Dashwood, R.H. 2006. Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apcmin mice. FASEB J. 20:506-508.
-
(2006)
FASEB J.
, vol.20
, pp. 506-508
-
-
Myzak, M.C.1
Dashwood, W.M.2
Orner, G.A.3
Ho, E.4
Dashwood, R.H.5
-
44
-
-
0032406798
-
Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables
-
Shapiro, T.A., Fahey, J.W., Wade, K.L., Stephenson, K.K. and Talalay, P. 1998. Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables. Cancer Epidemiol. Biomarkers Prev. 7:1091-1100.
-
(1998)
Cancer Epidemiol. Biomarkers Prev.
, vol.7
, pp. 1091-1100
-
-
Shapiro, T.A.1
Fahey, J.W.2
Wade, K.L.3
Stephenson, K.K.4
Talalay, P.5
-
45
-
-
0034928041
-
Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: Metabolism and excretion in humans
-
Shapiro, T.A., Fahey, J.W., Wade, K.L., Stephenson, K.K. and Talalay, P. 2001. Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans. Cancer Epidemiol. Biomarkers Prev. 10:501-508.
-
(2001)
Cancer Epidemiol. Biomarkers Prev.
, vol.10
, pp. 501-508
-
-
Shapiro, T.A.1
Fahey, J.W.2
Wade, K.L.3
Stephenson, K.K.4
Talalay, P.5
-
46
-
-
33749165612
-
Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: A clinical phase i study
-
Shapiro, T.A., Fahey, J.W., Dinkova-Kostova, A.T., Holtzclaw, W.D., Stephenson, K.K., Wade, K.L., Ye, L. and Talalay, P. 2006. Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study. Nutr. Cancer 55:53-62.
-
(2006)
Nutr. Cancer
, vol.55
, pp. 53-62
-
-
Shapiro, T.A.1
Fahey, J.W.2
Dinkova-Kostova, A.T.3
Holtzclaw, W.D.4
Stephenson, K.K.5
Wade, K.L.6
Ye, L.7
Talalay, P.8
-
47
-
-
4544247421
-
Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells
-
Svehlíková, V., Wang, S., Jakubíková, J., Williamson, G., Mithen, R. and Bao, Y. 2004. Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells. Carcinogenesis 25:1629-1637.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1629-1637
-
-
Svehlíková, V.1
Wang, S.2
Jakubíková, J.3
Williamson, G.4
Mithen, R.5
Bao, Y.6
-
48
-
-
0034490852
-
Chemoprotection against cancer by induction of phase 2 enzymes
-
Talalay, P. 2000. Chemoprotection against cancer by induction of phase 2 enzymes. BioFactors 12:5-11.
-
(2000)
BioFactors
, vol.12
, pp. 5-11
-
-
Talalay, P.1
-
49
-
-
0035170990
-
Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism
-
Talalay, P. and Fahey, J.W. 2001. Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism. J. Nutrition 131:3027S-3033S.
-
(2001)
J. Nutrition
, vol.131
-
-
Talalay, P.1
Fahey, J.W.2
-
50
-
-
36849089479
-
Sulforaphane mobilizes cellular defenses that protect6 skin against damage by UV radiation
-
Talalay, P., Fahey, J.W., Healy, Z.R., Wehage, S.L., Benedict, A.L., Min, C. and Dinkova-Kostova, A.T. 2007. Sulforaphane mobilizes cellular defenses that protect6 skin against damage by UV radiation. Proc. Natl. Acad. Sci. USA 104:17500-17505.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 17500-17505
-
-
Talalay, P.1
Fahey, J.W.2
Healy, Z.R.3
Wehage, S.L.4
Benedict, A.L.5
Min, C.6
Dinkova-Kostova, A.T.7
-
51
-
-
0037106099
-
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
-
Thimmulappa, R.K., Mai, K.H., Srisuma, S., Kensler, T.W., Yamamoto, M. and Biswal, S. 2002. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res. 62:5196-5203.
-
(2002)
Cancer Res.
, vol.62
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
52
-
-
23244450241
-
Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane
-
Traka, M., Gasper, A.V., Smith, J.A., Hawkey, C.J., Bao, Y. and Mithen, R.F. 2005. Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. J. Nutr. 135:1865-1872.
-
(2005)
J. Nutr.
, vol.135
, pp. 1865-1872
-
-
Traka, M.1
Gasper, A.V.2
Smith, J.A.3
Hawkey, C.J.4
Bao, Y.5
Mithen, R.F.6
-
53
-
-
49849087443
-
Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate
-
Traka, M., Gasper, A.V., Melchini, A., Bacon, J.R., Needs, P.W., Frost, V., Chantry, A., Jones, A.M., Ortori, C.A., Barrett, D.A., Ball, R.Y., Mills, R.D. and Mithen, R.F. 2008. Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate. PLoS ONE 3:e2568.
-
(2008)
PLoS ONE
, vol.3
-
-
Traka, M.1
Gasper, A.V.2
Melchini, A.3
Bacon, J.R.4
Needs, P.W.5
Frost, V.6
Chantry, A.7
Jones, A.M.8
Ortori, C.A.9
Barrett, D.A.10
Ball, R.Y.11
Mills, R.D.12
Mithen, R.F.13
-
54
-
-
35748952490
-
Sulforaphane suppresses lipopolysaccharide-induced cyclooxygenase-2 (COX-2) expression through the modulation of multiple targets in COX-2 gene promoter
-
Woo, K.J. and Kwon, T.K. 2007. Sulforaphane suppresses lipopolysaccharide-induced cyclooxygenase-2 (COX-2) expression through the modulation of multiple targets in COX-2 gene promoter. Int. Immunopharmacol. 7:1776-1783.
-
(2007)
Int. Immunopharmacol.
, vol.7
, pp. 1776-1783
-
-
Woo, K.J.1
Kwon, T.K.2
-
55
-
-
33748089664
-
Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2
-
Xu, C., Huang, M.T., Shen, G., Yuan, X., Lin, W., Khor, T.O., Conney, A.H. and Kong, A.N. 2006. Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2. Cancer Res. 66:8293-8296.
-
(2006)
Cancer Res.
, vol.66
, pp. 8293-8296
-
-
Xu, C.1
Huang, M.T.2
Shen, G.3
Yuan, X.4
Lin, W.5
Khor, T.O.6
Conney, A.H.7
Kong, A.N.8
-
56
-
-
0035681887
-
Total intracellular accumulation levels of dietary isothiocyanates determine their activity in elevation of cellular glutathione and induction of Phase 2 detoxification enzymes
-
Ye, L. and Zhang, Y. 2001. Total intracellular accumulation levels of dietary isothiocyanates determine their activity in elevation of cellular glutathione and induction of Phase 2 detoxification enzymes. Carcinogenesis 22:1987-1992.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1987-1992
-
-
Ye, L.1
Zhang, Y.2
-
57
-
-
0036135910
-
Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: Pharmacokinetics of broccoli sprout isothiocyanates in humans
-
Ye, L., Dinkova-Kostova, A.T., Wade, K.L., Zhang, Y., Shapiro, T.A. and Talalay, P. 2002. Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans. Clin. Chim. Acta 316:43-53.
-
(2002)
Clin. Chim. Acta
, vol.316
, pp. 43-53
-
-
Ye, L.1
Dinkova-Kostova, A.T.2
Wade, K.L.3
Zhang, Y.4
Shapiro, T.A.5
Talalay, P.6
-
58
-
-
0035094701
-
Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates
-
Zhang, Y. 2001. Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates. Carcinogenesis 22:425-431.
-
(2001)
Carcinogenesis
, vol.22
, pp. 425-431
-
-
Zhang, Y.1
-
59
-
-
0345700812
-
Synergy between sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation
-
Zhang, J., Svehlíková, V., Bao, Y., Howie, A.F., Beckett, G.J. and Williamson, G. 2003. Synergy between sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation. Carcinogenesis 24:497-503.
-
(2003)
Carcinogenesis
, vol.24
, pp. 497-503
-
-
Zhang, J.1
Svehlíková, V.2
Bao, Y.3
Howie, A.F.4
Beckett, G.J.5
Williamson, G.6
-
60
-
-
0026577605
-
A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure
-
Zhang, Y., Talalay, P., Cho, C.G. and Posner, G.H. 1992. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc. Natl. Acad. Sci. USA 89:2399-2403.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2399-2403
-
-
Zhang, Y.1
Talalay, P.2
Cho, C.G.3
Posner, G.H.4
-
61
-
-
0026783989
-
Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols
-
Zhang, Y., Cho, C.G., Posner, G.H. and Talalay, P. 1992. Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols. Anal. Biochem. 205:100-107.
-
(1992)
Anal. Biochem.
, vol.205
, pp. 100-107
-
-
Zhang, Y.1
Cho, C.G.2
Posner, G.H.3
Talalay, P.4
-
62
-
-
0028203252
-
Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
-
Zhang, Y., Kensler, T.W., Cho, C.G., Posner, G.H. and Talalay, P. 1994. Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Proc. Natl. Acad. Sci. USA 91:3147-3150.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3147-3150
-
-
Zhang, Y.1
Kensler, T.W.2
Cho, C.G.3
Posner, G.H.4
Talalay, P.5
-
63
-
-
0030219693
-
Quantitative determination of isothiocyanates, dithiocarbamates, carbon disulfide, and related thiocarbonyl compounds by cyclocondensation with 1,2-benzenedithiol
-
Zhang, Y., Wade, K.L., Prestera, T. and Talalay, P. 1996. Quantitative determination of isothiocyanates, dithiocarbamates, carbon disulfide, and related thiocarbonyl compounds by cyclocondensation with 1,2-benzenedithiol. Anal. Biochem. 239:160-167.
-
(1996)
Anal. Biochem.
, vol.239
, pp. 160-167
-
-
Zhang, Y.1
Wade, K.L.2
Prestera, T.3
Talalay, P.4
-
64
-
-
33846153232
-
Induction of GST and NQO1 in cultured bladder cells and in the urinary bladders of rats by an extract of broccoli (Brassica oleracea italica) sprouts
-
Zhang, Y., Munday, R., Jobson, H.E., Munday, C.M., Lister, C., Wilson, P., Fahey, J.W. and Mhawech-Fauceglia, P. 2006. Induction of GST and NQO1 in cultured bladder cells and in the urinary bladders of rats by an extract of broccoli (Brassica oleracea italica) sprouts. J. Agric. Food Chem. 54:9370-9376.
-
(2006)
J. Agric. Food Chem.
, vol.54
, pp. 9370-9376
-
-
Zhang, Y.1
Munday, R.2
Jobson, H.E.3
Munday, C.M.4
Lister, C.5
Wilson, P.6
Fahey, J.W.7
Mhawech-Fauceglia, P.8
-
65
-
-
34548445866
-
Discovery and development of sulforaphane as a cancer chemopreventive phytochemical
-
Zhang, Y. and Tang, L. 2007. Discovery and development of sulforaphane as a cancer chemopreventive phytochemical. Acta Pharmacol. Sin. 28:1343-1354.
-
(2007)
Acta Pharmacol. Sin.
, vol.28
, pp. 1343-1354
-
-
Zhang, Y.1
Tang, L.2
|