-
1
-
-
7244245762
-
Finishing the euchromatic sequence of the human genome
-
Finishing the euchromatic sequence of the human genome. Nature 2004;431:931-45.
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
-
2
-
-
79959524146
-
A haplotype map of the human genome
-
A haplotype map of the human genome. Nature 2005;437:1299-320.
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
3
-
-
35348983887
-
A second generation human haplotype map of over 3.1 million SNPs
-
Frazer KA, Ballinger DG, Cox DR, et al. A second generation human haplotype map of over 3.1 million SNPs. Nature 2007;449:851-61.
-
(2007)
Nature
, vol.449
, pp. 851-861
-
-
Frazer, K.A.1
Ballinger, D.G.2
Cox, D.R.3
-
4
-
-
28944433632
-
The personalized medicine coalition: Goals and strategies
-
DOI 10.2165/00129785-200505060-00002
-
Abrahams E, Ginsburg GS, Silver M. The Personalized Medicine Coalition: goals and strategies. Am J Pharmacogenomics 2005;5:345-55. (Pubitemid 41783781)
-
(2005)
American Journal of PharmacoGenomics
, vol.5
, Issue.6
, pp. 345-355
-
-
Abrahams, E.1
Ginsburg, G.S.2
Silver, M.3
-
6
-
-
0035575568
-
Personalized medicine: Revolutionizing drug discovery and patient care
-
Ginsburg GS, McCarthy JJ. Personalized medicine: revolutionizing drug discovery and patient care. Trends Biotechnol 2001;19:491-6.
-
(2001)
Trends Biotechnol
, vol.19
, pp. 491-496
-
-
Ginsburg, G.S.1
McCarthy, J.J.2
-
7
-
-
43449094338
-
Is personalized medicine finally arriving?
-
Allison M. Is personalized medicine finally arriving? Nat Biotechnol 2008;26:509-17.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 509-517
-
-
Allison, M.1
-
8
-
-
70449465250
-
Genomic and personalized medicine: Foundations and applications
-
Ginsburg GS, Willard HF. Genomic and personalized medicine: foundations and applications. Transl Res 2009;154:277-87.
-
(2009)
Transl Res
, vol.154
, pp. 277-287
-
-
Ginsburg, G.S.1
Willard, H.F.2
-
9
-
-
0018141482
-
Tumor heterogeneity and the biology of cancer invasion and metastasis
-
Fidler IJ. Tumor heterogeneity and the biology of cancer invasion and metastasis. Cancer Res 1978;38:2651-60.
-
(1978)
Cancer Res
, vol.38
, pp. 2651-2660
-
-
Fidler, I.J.1
-
10
-
-
64149105211
-
Utilizing the molecular gateway: The path to personalized cancer management
-
Overdevest JB, Theodorescu D, Lee JK. Utilizing the molecular gateway: the path to personalized cancer management. Clin Chem 2009;55:684-97.
-
(2009)
Clin Chem
, vol.55
, pp. 684-697
-
-
Overdevest, J.B.1
Theodorescu, D.2
Lee, J.K.3
-
11
-
-
0030686551
-
Environment and cancer: Who are susceptible?
-
Perera FP. Environment and cancer: who are susceptible? Science 1997;278:1068-73.
-
(1997)
Science
, vol.278
, pp. 1068-1073
-
-
Perera, F.P.1
-
12
-
-
34447335843
-
Cancer risks in carriers of the BRCA1/2 Ashkenazi founder mutations
-
Kadouri L, Hubert A, Rotenberg Y, et al. Cancer risks in carriers of the BRCA1/2 Ashkenazi founder mutations. J Med Genet 2007;44:467-71.
-
(2007)
J Med Genet
, vol.44
, pp. 467-471
-
-
Kadouri, L.1
Hubert, A.2
Rotenberg, Y.3
-
13
-
-
67649211353
-
Genetics and personal genomics for personalized breast cancer surgery: Progress and challenges in research and clinical practice
-
Ziogas D, Roukos DH. Genetics and personal genomics for personalized breast cancer surgery: progress and challenges in research and clinical practice. Ann Surg Oncol 2009;16:1771-82.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 1771-1782
-
-
Ziogas, D.1
Roukos, D.H.2
-
14
-
-
35148861546
-
Individualized preventive and therapeutic management of hereditary breast ovarian cancer syndrome
-
Roukos DH, Briasoulis E. Individualized preventive and therapeutic management of hereditary breast ovarian cancer syndrome. Nat Clin Pract Oncol 2007;4:578-90.
-
(2007)
Nat Clin Pract Oncol
, vol.4
, pp. 578-590
-
-
Roukos, D.H.1
Briasoulis, E.2
-
15
-
-
33645675556
-
Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: An update
-
Gronwald J, Tung N, Foulkes WD, et al. Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: an update. Int J Cancer 2006;118:2281-4.
-
(2006)
Int J Cancer
, vol.118
, pp. 2281-2284
-
-
Gronwald, J.1
Tung, N.2
Foulkes, W.D.3
-
16
-
-
67349284098
-
Response to neoadjuvant therapy with cisplatin in BRCA1-positive breast cancer patients
-
Byrski T, Huzarski T, Dent R, et al. Response to neoadjuvant therapy with cisplatin in BRCA1-positive breast cancer patients. Breast Cancer Res Treat 2009;115:359-63.
-
(2009)
Breast Cancer Res Treat
, vol.115
, pp. 359-363
-
-
Byrski, T.1
Huzarski, T.2
Dent, R.3
-
17
-
-
0036178190
-
Current understanding of the epidemiology and clinical implications of BRCA1 and BRCA2 mutations for ovarian cancer
-
DOI 10.1097/00001703-200202000-00004
-
Narod SA, Boyd J. Current understanding of the epidemiology and clinical implications of BRCA1 and BRCA2 mutations for ovarian cancer. Curr Opin Obstet Gynecol 2002;14:19-26. (Pubitemid 34177903)
-
(2002)
Current Opinion in Obstetrics and Gynecology
, vol.14
, Issue.1
, pp. 19-26
-
-
Narod, S.A.1
Boyd, J.2
-
18
-
-
34548415428
-
The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancers
-
Friedenson B. The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancers. BMC Cancer 2007;7:152.
-
(2007)
BMC Cancer
, vol.7
, pp. 152
-
-
Friedenson, B.1
-
19
-
-
77950650763
-
Germline BRCA mutations denote a clinicopathologic subset of prostate cancer
-
Gallagher DJ, Gaudet MM, Pal P, et al. Germline BRCA mutations denote a clinicopathologic subset of prostate cancer. Clin Cancer Res 2010;16:2115-21.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2115-2121
-
-
Gallagher, D.J.1
Gaudet, M.M.2
Pal, P.3
-
20
-
-
41649107292
-
Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer: A multicenter, prospective study
-
Kauff ND, Domchek SM, Friebel TM, et al. Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer: a multicenter, prospective study. J Clin Oncol 2008;26:1331-7.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1331-1337
-
-
Kauff, N.D.1
Domchek, S.M.2
Friebel, T.M.3
-
21
-
-
32544442522
-
BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells
-
Fan S, Meng Q, Auborn K, Carter T, Rosen EM. BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells. Br J Cancer 2006;94:407-26.
-
(2006)
Br J Cancer
, vol.94
, pp. 407-426
-
-
Fan, S.1
Meng, Q.2
Auborn, K.3
Carter, T.4
Rosen, E.M.5
-
22
-
-
0030948865
-
Mutations predisposing to hereditary nonpolyposis colorectal cancer
-
Peltomaki P, de la Chapelle A. Mutations predisposing to hereditary nonpolyposis colorectal cancer. Adv Cancer Res 1997;71:93-119.
-
(1997)
Adv Cancer Res
, vol.71
, pp. 93-119
-
-
Peltomaki, P.1
De La Chapelle, A.2
-
23
-
-
0028088256
-
Clinical screening as compared with DNA analysis in families with multiple endocrine neoplasia type 2A
-
Lips CJ, Landsvater RM, Hoppener JW, et al. Clinical screening as compared with DNA analysis in families with multiple endocrine neoplasia type 2A. N Engl J Med 1994;331:828-35.
-
(1994)
N Engl J Med
, vol.331
, pp. 828-835
-
-
Lips, C.J.1
Landsvater, R.M.2
Hoppener, J.W.3
-
24
-
-
75549087826
-
COSMIC (the Catalogue of Somatic Mutations in Cancer): A resource to investigate acquired mutations in human cancer
-
Forbes SA, Tang G, Bindal N, et al. COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer. Nucleic Acids Res 2010;38:D652-7.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Forbes, S.A.1
Tang, G.2
Bindal, N.3
-
25
-
-
69349095448
-
Genomic and mutational profiling to assess clonal relationships between multiple non-small cell lung cancers
-
Girard N, Ostrovnaya I, Lau C, et al. Genomic and mutational profiling to assess clonal relationships between multiple non-small cell lung cancers. Clin Cancer Res 2009;15:5184-90.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5184-5190
-
-
Girard, N.1
Ostrovnaya, I.2
Lau, C.3
-
26
-
-
59049106305
-
Molecular and phenotypic analysis of poorly differentiated sinonasal neoplasms: An integrated approach for early diagnosis and classification
-
Cordes B, Williams MD, Tirado Y, et al. Molecular and phenotypic analysis of poorly differentiated sinonasal neoplasms: an integrated approach for early diagnosis and classification. Hum Pathol 2009;40:283-92.
-
(2009)
Hum Pathol
, vol.40
, pp. 283-292
-
-
Cordes, B.1
Williams, M.D.2
Tirado, Y.3
-
27
-
-
59649085853
-
Molecular classification of rhabdomyosarcoma-genotypic and phenotypic determinants of diagnosis: A report from the Children's Oncology Group
-
Davicioni E, Anderson MJ, Finckenstein FG, et al. Molecular classification of rhabdomyosarcoma-genotypic and phenotypic determinants of diagnosis: a report from the Children's Oncology Group. Am J Pathol 2009;174:550-64.
-
(2009)
Am J Pathol
, vol.174
, pp. 550-564
-
-
Davicioni, E.1
Anderson, M.J.2
Finckenstein, F.G.3
-
28
-
-
67651149987
-
Pathobiology and molecular profiling of peripheral T-cell lymphomas
-
de Leval L, Gaulard P. Pathobiology and molecular profiling of peripheral T-cell lymphomas. Hematol Am Soc Hematol Educ Program 2008:272-9.
-
(2008)
Hematol Am Soc Hematol Educ Program
, pp. 272-279
-
-
De Leval, L.1
Gaulard, P.2
-
29
-
-
27244437619
-
Gene expression profiling in acute myeloid leukemia
-
Bullinger L, Valk PJ. Gene expression profiling in acute myeloid leukemia. J Clin Oncol 2005;23:6296-305.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6296-6305
-
-
Bullinger, L.1
Valk, P.J.2
-
30
-
-
70449429509
-
Gene expression profiling of minimally differentiated acute myeloid leukemia: M0 is a distinct entity subdivided by RUNX1 mutation status
-
Silva FP, Swagemakers SM, Erpelinck-Verschueren C, et al. Gene expression profiling of minimally differentiated acute myeloid leukemia: M0 is a distinct entity subdivided by RUNX1 mutation status. Blood 2009;114:3001-7.
-
(2009)
Blood
, vol.114
, pp. 3001-3007
-
-
Silva, F.P.1
Swagemakers, S.M.2
Erpelinck-Verschueren, C.3
-
31
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, NF1
-
Verhaak RG, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, NF1. Cancer Cell 2010;17:98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
32
-
-
73349089659
-
Presenting features of breast cancer differ by molecular subtype
-
Wiechmann L, Sampson M, Stempel M, et al. Presenting features of breast cancer differ by molecular subtype. Ann Surg Oncol 2009;16:2705-10.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 2705-2710
-
-
Wiechmann, L.1
Sampson, M.2
Stempel, M.3
-
33
-
-
77949877463
-
Prognostic applications of gene expression signatures in breast cancer
-
Normanno N, De Luca A, Carotenuto P, Lamura L, Oliva I, D'Alessio A. Prognostic applications of gene expression signatures in breast cancer. Oncology 2009;77 Suppl 1:2-8.
-
(2009)
Oncology
, vol.77
, Issue.SUPPL. 1
, pp. 2-8
-
-
Normanno, N.1
De Luca, A.2
Carotenuto, P.3
Lamura, L.4
Oliva, I.5
D'Alessio, A.6
-
34
-
-
74949115627
-
Mining tissue microarray data to uncover combinations of biomarker expression patterns that improve intermediate staging and grading of clear cell renal cell cancer
-
Dahinden C, Ingold B, Wild P, et al. Mining tissue microarray data to uncover combinations of biomarker expression patterns that improve intermediate staging and grading of clear cell renal cell cancer. Clin Cancer Res 2010;16:88-98.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 88-98
-
-
Dahinden, C.1
Ingold, B.2
Wild, P.3
-
35
-
-
64949201827
-
From bench to bedside: Current and future applications of molecular profiling in renal cell carcinoma
-
Arsanious A, Bjarnason GA, Yousef GM. From bench to bedside: current and future applications of molecular profiling in renal cell carcinoma. Mol Cancer 2009;8:20.
-
(2009)
Mol Cancer
, vol.8
, pp. 20
-
-
Arsanious, A.1
Bjarnason, G.A.2
Yousef, G.M.3
-
36
-
-
33645279862
-
Molecular diagnosis of Burkitt's lymphoma
-
Dave SS, Fu K, Wright GW, et al. Molecular diagnosis of Burkitt's lymphoma. N Engl J Med 2006;354:2431-42.
-
(2006)
N Engl J Med
, vol.354
, pp. 2431-2442
-
-
Dave, S.S.1
Fu, K.2
Wright, G.W.3
-
37
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001;344:1031-7.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
38
-
-
0035899418
-
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: Biological and clinical implications
-
Tuveson DA, Willis NA, Jacks T, et al. STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications. Oncogene 2001;20:5054-8.
-
(2001)
Oncogene
, vol.20
, pp. 5054-5058
-
-
Tuveson, D.A.1
Willis, N.A.2
Jacks, T.3
-
39
-
-
0032127350
-
Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
-
Baselga J, Norton L, Albanell J, Kim YM, Mendelsohn J. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res 1998;58:2825-31.
-
(1998)
Cancer Res
, vol.58
, pp. 2825-2831
-
-
Baselga, J.1
Norton, L.2
Albanell, J.3
Kim, Y.M.4
Mendelsohn, J.5
-
40
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
41
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004;101:13306-11.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
42
-
-
33746933434
-
Effect of epidermal growth factor receptor tyrosine kinase domain mutations on the outcome of patients with non-small cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors
-
Janne PA, Johnson BE. Effect of epidermal growth factor receptor tyrosine kinase domain mutations on the outcome of patients with non-small cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors. Clin Cancer Res 2006;12:4416-20s.
-
(2006)
Clin Cancer Res
, vol.12
-
-
Janne, P.A.1
Johnson, B.E.2
-
43
-
-
34249810645
-
KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Massarelli E, Varella-Garcia M, Tang X, et al. KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin Cancer Res 2007;13:2890-6.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2890-2896
-
-
Massarelli, E.1
Varella-Garcia, M.2
Tang, X.3
-
44
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:1626-34.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
45
-
-
33646228635
-
KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
-
Lievre A, Bachet JB, Le CD, et al. KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res 2006;66:3992-5.
-
(2006)
Cancer Res
, vol.66
, pp. 3992-3995
-
-
Lievre, A.1
Bachet, J.B.2
Le, C.D.3
-
46
-
-
65349189958
-
American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
-
Allegra CJ, Jessup JM, Somerfield MR, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol 2009;27:2091-6.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2091-2096
-
-
Allegra, C.J.1
Jessup, J.M.2
Somerfield, M.R.3
-
47
-
-
47249146141
-
Lessons from Tarceva in pancreatic cancer: Where are we now, and how should future trials be designed in pancreatic cancer?
-
Laurent-Puig P, Taieb J. Lessons from Tarceva in pancreatic cancer: where are we now, and how should future trials be designed in pancreatic cancer? Curr Opin Oncol 2008;20:454-8.
-
(2008)
Curr Opin Oncol
, vol.20
, pp. 454-458
-
-
Laurent-Puig, P.1
Taieb, J.2
-
48
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 1999;286:487-91.
-
(1999)
Science
, vol.286
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
49
-
-
77449136592
-
Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment
-
Rodriguez-Antona C, Gomez A, Karlgren M, Sim SC, Ingelman- Sundberg M. Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment. Hum Genet 2010;127:1-17.
-
(2010)
Hum Genet
, vol.127
, pp. 1-17
-
-
Rodriguez-Antona, C.1
Gomez, A.2
Karlgren, M.3
Sim, S.C.4
Ingelman- Sundberg, M.5
-
50
-
-
0037184794
-
Polymorphism of cytochrome P450 and xenobiotic toxicity
-
DOI 10.1016/S0300-483X(02)00492-4, PII S0300483X02004924
-
Ingelman-Sundberg M. Polymorphism of cytochrome P450 and xenobiotic toxicity. Toxicology 2002;181-182:447-52. (Pubitemid 36015735)
-
(2002)
Toxicology
, vol.181-182
, pp. 447-452
-
-
Ingelman-Sundberg, M.1
-
51
-
-
0032522873
-
Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
-
Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 1998;279:1200-5.
-
(1998)
JAMA
, vol.279
, pp. 1200-1205
-
-
Lazarou, J.1
Pomeranz, B.H.2
Corey, P.N.3
-
52
-
-
53249086540
-
Impaired tamoxifen metabolism reduces survival in familial breast cancer patients
-
Newman WG, Hadfield KD, Latif A, et al. Impaired tamoxifen metabolism reduces survival in familial breast cancer patients. Clin Cancer Res 2008;14:5913-8.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5913-5918
-
-
Newman, W.G.1
Hadfield, K.D.2
Latif, A.3
-
53
-
-
33745092788
-
Genetic variation in ABCB1 influences paclitaxel pharmacokinetics in Japanese patients with ovarian cancer
-
Yamaguchi H, Hishinuma T, Endo N, et al. Genetic variation in ABCB1 influences paclitaxel pharmacokinetics in Japanese patients with ovarian cancer. Int J Gynecol Cancer 2006;16:979-85.
-
(2006)
Int J Gynecol Cancer
, vol.16
, pp. 979-985
-
-
Yamaguchi, H.1
Hishinuma, T.2
Endo, N.3
-
54
-
-
53049085702
-
ABCB1 (MDR 1) polymorphisms and progression-free survival among women with ovarian cancer following paclitaxel/carboplatin chemotherapy
-
Johnatty SE, Beesley J, Paul J, et al. ABCB1 (MDR 1) polymorphisms and progression-free survival among women with ovarian cancer following paclitaxel/carboplatin chemotherapy. Clin Cancer Res 2008;14:5594-601.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5594-5601
-
-
Johnatty, S.E.1
Beesley, J.2
Paul, J.3
-
55
-
-
48249123433
-
Pharmacogenomic biomarker information in drug labels approved by the United States food and drug administration: Prevalence of related drug use
-
Frueh FW, Amur S, Mummaneni P, et al. Pharmacogenomic biomarker information in drug labels approved by the United States food and drug administration: prevalence of related drug use. Pharmacotherapy 2008;28:992-8.
-
(2008)
Pharmacotherapy
, vol.28
, pp. 992-998
-
-
Frueh, F.W.1
Amur, S.2
Mummaneni, P.3
-
56
-
-
0036328380
-
Application of microarrays to the analysis of gene expression in cancer
-
Macgregor PF, Squire JA. Application of microarrays to the analysis of gene expression in cancer. Clin Chem 2002;48:1170-7.
-
(2002)
Clin Chem
, vol.48
, pp. 1170-1177
-
-
Macgregor, P.F.1
Squire, J.A.2
-
57
-
-
53849144620
-
Strategies for discovering novel cancer biomarkers through utilization of emerging technologies
-
Kulasingam V, Diamandis EP. Strategies for discovering novel cancer biomarkers through utilization of emerging technologies. Nat Clin Pract Oncol 2008;5:588-99.
-
(2008)
Nat Clin Pract Oncol
, vol.5
, pp. 588-599
-
-
Kulasingam, V.1
Diamandis, E.P.2
-
58
-
-
70249106113
-
Virtual-karyotyping with SNP microarrays in morphologically challenging renal cell neoplasms: A practical and useful diagnostic modality
-
Kim HJ, Shen SS, Ayala AG, et al. Virtual-karyotyping with SNP microarrays in morphologically challenging renal cell neoplasms: a practical and useful diagnostic modality. Am J Surg Pathol 2009;33:1276-86.
-
(2009)
Am J Surg Pathol
, vol.33
, pp. 1276-1286
-
-
Kim, H.J.1
Shen, S.S.2
Ayala, A.G.3
-
59
-
-
37349063133
-
Use of the Oncotype DX 21-gene assay to guide adjuvant decision making in early-stage breast cancer
-
Conlin AK, Seidman AD. Use of the Oncotype DX 21-gene assay to guide adjuvant decision making in early-stage breast cancer. Mol Diagn Ther 2007;11:355-60.
-
(2007)
Mol Diagn Ther
, vol.11
, pp. 355-360
-
-
Conlin, A.K.1
Seidman, A.D.2
-
60
-
-
42249087308
-
The complete genome of an individual by massively parallel DNA sequencing
-
Wheeler DA, Srinivasan M, Egholm M, et al. The complete genome of an individual by massively parallel DNA sequencing. Nature 2008;452:872-6.
-
(2008)
Nature
, vol.452
, pp. 872-876
-
-
Wheeler, D.A.1
Srinivasan, M.2
Egholm, M.3
-
61
-
-
37749031255
-
Next-generation sequencing transforms today's biology
-
Schuster SC. Next-generation sequencing transforms today's biology. Nat Methods 2008;5:16-8.
-
(2008)
Nat Methods
, vol.5
, pp. 16-18
-
-
Schuster, S.C.1
-
62
-
-
0030298490
-
Real-time DNA sequencing using detection of pyrophosphate release
-
Ronaghi M, Karamohamed S, Pettersson B, Uhlen M, Nyren P. Real-time DNA sequencing using detection of pyrophosphate release. Anal Biochem 1996;242:84-9.
-
(1996)
Anal Biochem
, vol.242
, pp. 84-89
-
-
Ronaghi, M.1
Karamohamed, S.2
Pettersson, B.3
Uhlen, M.4
Nyren, P.5
-
63
-
-
33847293670
-
High-throughput oncogene mutation profiling in human cancer
-
Thomas RK, Baker AC, Debiasi RM, et al. High-throughput oncogene mutation profiling in human cancer. Nat Genet 2007;39:347-51.
-
(2007)
Nat Genet
, vol.39
, pp. 347-351
-
-
Thomas, R.K.1
Baker, A.C.2
Debiasi, R.M.3
-
64
-
-
72949119310
-
Complex landscapes of somatic rearrangement in human breast cancer genomes
-
Stephens PJ, McBride DJ, Lin ML, et al. Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature 2009;462:1005-10.
-
(2009)
Nature
, vol.462
, pp. 1005-1010
-
-
Stephens, P.J.1
McBride, D.J.2
Lin, M.L.3
-
66
-
-
0038102259
-
Sequence-based cancer genomics: Progress, lessons and opportunities
-
DOI 10.1038/nrg1085
-
Strausberg RL, Simpson AJ, Wooster R. Sequence-based cancer genomics: progress, lessons and opportunities. Nat Rev Genet 2003;4:409-18. (Pubitemid 36648141)
-
(2003)
Nature Reviews Genetics
, vol.4
, Issue.6
, pp. 409-418
-
-
Strausberg, R.L.1
Simpson, A.J.G.2
Wooster, R.3
-
67
-
-
62049085786
-
Transcriptome sequencing to detect gene fusions in cancer
-
Maher CA, Kumar-Sinha C, Cao X, et al. Transcriptome sequencing to detect gene fusions in cancer. Nature 2009;458:97-101.
-
(2009)
Nature
, vol.458
, pp. 97-101
-
-
Maher, C.A.1
Kumar-Sinha, C.2
Cao, X.3
-
68
-
-
53649088131
-
Applications of next-generation sequencing technologies in functional genomics
-
Morozova O, Marra MA. Applications of next-generation sequencing technologies in functional genomics. Genomics 2008;92:255-64.
-
(2008)
Genomics
, vol.92
, pp. 255-264
-
-
Morozova, O.1
Marra, M.A.2
-
69
-
-
10744230697
-
A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes
-
Ley TJ, Minx PJ, Walter MJ, et al. A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proc Natl Acad Sci U S A 2003;100:14275-80.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 14275-14280
-
-
Ley, T.J.1
Minx, P.J.2
Walter, M.J.3
-
70
-
-
61849150985
-
High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients
-
Tyner JW, Erickson H, Deininger MW, et al. High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients. Blood 2009;113:1749-55.
-
(2009)
Blood
, vol.113
, pp. 1749-1755
-
-
Tyner, J.W.1
Erickson, H.2
Deininger, M.W.3
-
71
-
-
60549092281
-
Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line
-
Zhao Q, Caballero OL, Levy S, et al. Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line. Proc Natl Acad Sci U S A 2009;106:1886-91.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1886-1891
-
-
Zhao, Q.1
Caballero, O.L.2
Levy, S.3
-
72
-
-
77249119762
-
The landscape of somatic copy-number alteration across human cancers
-
Beroukhim R, Mermel CH, Porter D, et al. The landscape of somatic copy-number alteration across human cancers. Nature 2010;463:899-905.
-
(2010)
Nature
, vol.463
, pp. 899-905
-
-
Beroukhim, R.1
Mermel, C.H.2
Porter, D.3
-
73
-
-
77949740366
-
Next generation sequencing of serum circulating nucleic acids from patients with invasive ductal breast cancer reveals differences to healthy and nonmalignant controls
-
Beck J, Urnovitz HB, Mitchell WM, Schutz E. Next generation sequencing of serum circulating nucleic acids from patients with invasive ductal breast cancer reveals differences to healthy and nonmalignant controls. Mol Cancer Res 2010;8:335-42.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 335-342
-
-
Beck, J.1
Urnovitz, H.B.2
Mitchell, W.M.3
Schutz, E.4
-
74
-
-
51049084870
-
Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors
-
Nickerson ML, Jaeger E, Shi Y, et al. Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors. Clin Cancer Res 2008;14:4726-34.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4726-4734
-
-
Nickerson, M.L.1
Jaeger, E.2
Shi, Y.3
-
75
-
-
74949138753
-
Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays
-
Drmanac R, Sparks AB, Callow MJ, et al. Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays. Science 2010;327:78-81.
-
(2010)
Science
, vol.327
, pp. 78-81
-
-
Drmanac, R.1
Sparks, A.B.2
Callow, M.J.3
-
76
-
-
33645072440
-
Gene sequencing. The race for the $1000 genome
-
Service RF. Gene sequencing. The race for the $1000 genome. Science 2006;311:1544-6.
-
(2006)
Science
, vol.311
, pp. 1544-1546
-
-
Service, R.F.1
-
77
-
-
0032991552
-
Characterization of single-nucleotide polymorphisms in coding regions of human genes
-
Cargill M, Altshuler D, Ireland J, et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 1999;22:231-8.
-
(1999)
Nat Genet
, vol.22
, pp. 231-238
-
-
Cargill, M.1
Altshuler, D.2
Ireland, J.3
-
80
-
-
56049116741
-
Common genetic variation and human disease
-
Orr N, Chanock S. Common genetic variation and human disease. Adv Genet 2008;62:1-32.
-
(2008)
Adv Genet
, vol.62
, pp. 1-32
-
-
Orr, N.1
Chanock, S.2
-
81
-
-
40749113123
-
Genotyping platforms for mass-throughput genotyping with SNPs, including human genome-wide scans
-
Maresso K, Broeckel U. Genotyping platforms for mass-throughput genotyping with SNPs, including human genome-wide scans. Adv Genet 2008;60:107-39.
-
(2008)
Adv Genet
, vol.60
, pp. 107-139
-
-
Maresso, K.1
Broeckel, U.2
-
82
-
-
42349112088
-
Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
-
McCarthy MI, Abecasis GR, Cardon LR, et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 2008;9:356-69.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
-
83
-
-
0033865806
-
A system for specific, high-throughput genotyping by allele-specific primer extension on microarrays
-
Pastinen T, Raitio M, Lindroos K, Tainola P, Peltonen L, Syvanen AC. A system for specific, high-throughput genotyping by allele-specific primer extension on microarrays. Genome Res 2000;10:1031-42.
-
(2000)
Genome Res
, vol.10
, pp. 1031-1042
-
-
Pastinen, T.1
Raitio, M.2
Lindroos, K.3
Tainola, P.4
Peltonen, L.5
Syvanen, A.C.6
-
84
-
-
20044369371
-
Toward genome-wide SNP genotyping
-
Syvanen AC. Toward genome-wide SNP genotyping. Nat Genet 2005;37 Suppl:S5-10.
-
(2005)
Nat Genet
, vol.37
, Issue.SUPPL.
-
-
Syvanen, A.C.1
-
85
-
-
33749065163
-
Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-24 from a high-density SNP genome-wide linkage scan
-
Kemp Z, Carvajal-Carmona L, Spain S, et al. Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-24 from a high-density SNP genome-wide linkage scan. Hum Mol Genet 2006;15:2903-10.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 2903-2910
-
-
Kemp, Z.1
Carvajal-Carmona, L.2
Spain, S.3
-
86
-
-
50649087219
-
A genome-wide association screen identifies regions on chromosomes 1q25 and 7p21 as risk loci for sporadic prostate cancer
-
Nam RK, Zhang WW, Loblaw DA, et al. A genome-wide association screen identifies regions on chromosomes 1q25 and 7p21 as risk loci for sporadic prostate cancer. Prostate Cancer Prostatic Dis 2008;11:241-6.
-
(2008)
Prostate Cancer Prostatic Dis
, vol.11
, pp. 241-246
-
-
Nam, R.K.1
Zhang, W.W.2
Loblaw, D.A.3
-
87
-
-
22244478946
-
Polymorphisms of the dopamine receptor gene DRD2 and colorectal cancer risk
-
Gemignani F, Landi S, Moreno V, et al. Polymorphisms of the dopamine receptor gene DRD2 and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 2005;14:1633-8.
-
(2005)
Cancer Epidemiol Biomarkers Prev
, vol.14
, pp. 1633-1638
-
-
Gemignani, F.1
Landi, S.2
Moreno, V.3
-
88
-
-
77449122409
-
Single nucleotide polymorphism in the mutational hotspot of WT1 predicts a favorable outcome in patients with cytogenetically normal acute myeloid leukemia
-
Damm F, Heuser M, Morgan M, et al. Single nucleotide polymorphism in the mutational hotspot of WT1 predicts a favorable outcome in patients with cytogenetically normal acute myeloid leukemia. J Clin Oncol 2010;28:578-85.
-
(2010)
J Clin Oncol
, vol.28
, pp. 578-585
-
-
Damm, F.1
Heuser, M.2
Morgan, M.3
-
89
-
-
66849130885
-
Genome-wide analysis of survival in early-stage non-small-cell lung cancer
-
Huang YT, Heist RS, Chirieac LR, et al. Genome-wide analysis of survival in early-stage non-small-cell lung cancer. J Clin Oncol 2009;27:2660-7.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2660-2667
-
-
Huang, Y.T.1
Heist, R.S.2
Chirieac, L.R.3
-
90
-
-
67449162069
-
Polymorphisms in XRCC1 and XPG and response to platinum-based chemotherapy in advanced non-small cell lung cancer patients
-
Sun X, Li F, Sun N, et al. Polymorphisms in XRCC1 and XPG and response to platinum-based chemotherapy in advanced non-small cell lung cancer patients. Lung Cancer 2009;65:230-6.
-
(2009)
Lung Cancer
, vol.65
, pp. 230-236
-
-
Sun, X.1
Li, F.2
Sun, N.3
-
91
-
-
52649091186
-
Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia
-
Kujawski L, Ouillette P, Erba H, et al. Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia. Blood 2008;112:1993-2003.
-
(2008)
Blood
, vol.112
, pp. 1993-2003
-
-
Kujawski, L.1
Ouillette, P.2
Erba, H.3
-
92
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L, Ellis MJ, Li S, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010;464:999-1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
Ellis, M.J.2
Li, S.3
-
93
-
-
77953186827
-
Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer
-
Tada M, Kanai F, Tanaka Y, et al. Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer. Cancer Sci 2010;101:1261-9.
-
(2010)
Cancer Sci
, vol.101
, pp. 1261-1269
-
-
Tada, M.1
Kanai, F.2
Tanaka, Y.3
-
94
-
-
38949134183
-
Microarray-based expression profiling and informatics
-
Simon R. Microarray-based expression profiling and informatics. Curr Opin Biotechnol 2008;19:26-9.
-
(2008)
Curr Opin Biotechnol
, vol.19
, pp. 26-29
-
-
Simon, R.1
-
95
-
-
33747819585
-
Clinicopathologic significance of the basal-like subtype of breast cancer: A comparison with hormone receptor and Her2/neu-overexpressing phenotypes
-
DOI 10.1016/j.humpath.2006.04.015, PII S0046817706002644
-
Kim MJ, Ro JY, Ahn SH, Kim HH, Kim SB, Gong G. Clinicopathologic significance of the basal-like subtype of breast cancer: a comparison with hormone receptor and Her2/neu-overexpressing phenotypes. Hum Pathol 2006;37:1217-26. (Pubitemid 44286991)
-
(2006)
Human Pathology
, vol.37
, Issue.9
, pp. 1217-1226
-
-
Kim, M.-J.1
Ro, J.Y.2
Ahn, S.-H.3
Kim, H.H.4
Kim, S.-B.5
Gong, G.6
-
96
-
-
4344582207
-
Molecular diagnosis and outcome prediction in diffuse large B-cell lymphoma and other subtypes of lymphoma
-
Dybkaer K, Iqbal J, Zhou G, Chan WC. Molecular diagnosis and outcome prediction in diffuse large B-cell lymphoma and other subtypes of lymphoma. Clin Lymphoma 2004;5:19-28.
-
(2004)
Clin Lymphoma
, vol.5
, pp. 19-28
-
-
Dybkaer, K.1
Iqbal, J.2
Zhou, G.3
Chan, W.C.4
-
97
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
Golub TR, Slonim DK, Tamayo P, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999;286:531-7.
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
Slonim, D.K.2
Tamayo, P.3
-
98
-
-
0034598746
-
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
-
Alizadeh AA, Eisen MB, Davis RE, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000;403:503-11.
-
(2000)
Nature
, vol.403
, pp. 503-511
-
-
Alizadeh, A.A.1
Eisen, M.B.2
Davis, R.E.3
-
99
-
-
0034601455
-
Molecular classification of cutaneous malignant melanoma by gene expression profiling
-
Bittner M, Meltzer P, Chen Y, et al. Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature 2000;406:536-40.
-
(2000)
Nature
, vol.406
, pp. 536-540
-
-
Bittner, M.1
Meltzer, P.2
Chen, Y.3
-
100
-
-
18544365698
-
Gene-expression profiles predict survival of patients with lung adenocarcinoma
-
Beer DG, Kardia SL, Huang CC, et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 2002;8:816-24.
-
(2002)
Nat Med
, vol.8
, pp. 816-824
-
-
Beer, D.G.1
Kardia, S.L.2
Huang, C.C.3
-
101
-
-
33746875641
-
A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer
-
Potti A, Mukherjee S, Petersen R, et al. A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 2006;355:570-80.
-
(2006)
N Engl J Med
, vol.355
, pp. 570-580
-
-
Potti, A.1
Mukherjee, S.2
Petersen, R.3
-
102
-
-
0035939903
-
Delineation of prognostic biomarkers in prostate cancer
-
Dhanasekaran SM, Barrette TR, Ghosh D, et al. Delineation of prognostic biomarkers in prostate cancer. Nature 2001;412:822-6.
-
(2001)
Nature
, vol.412
, pp. 822-826
-
-
Dhanasekaran, S.M.1
Barrette, T.R.2
Ghosh, D.3
-
103
-
-
36549068221
-
Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: A substudy of the EORTC 10994/BIG 00-01 clinical trial
-
Bonnefoi H, Potti A, Delorenzi M, et al. Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial. Lancet Oncol 2007;8:1071-8.
-
(2007)
Lancet Oncol
, vol.8
, pp. 1071-1078
-
-
Bonnefoi, H.1
Potti, A.2
Delorenzi, M.3
-
104
-
-
32944465867
-
Unique gene expression profile based on pathologic response in epithelial ovarian cancer
-
Spentzos D, Levine DA, Kolia S, et al. Unique gene expression profile based on pathologic response in epithelial ovarian cancer. J Clin Oncol 2005;23:7911-8.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7911-7918
-
-
Spentzos, D.1
Levine, D.A.2
Kolia, S.3
-
105
-
-
33746143590
-
Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients
-
Frank O, Brors B, Fabarius A, et al. Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients. Leukemia 2006;20:1400-7.
-
(2006)
Leukemia
, vol.20
, pp. 1400-1407
-
-
Frank, O.1
Brors, B.2
Fabarius, A.3
-
106
-
-
33750727368
-
Genomic signatures to guide the use of chemotherapeutics
-
DOI 10.1038/nm1491, PII NM1491
-
Potti A, Dressman HK, Bild A, et al. Genomic signatures to guide the use of chemotherapeutics. Nat Med 2006;12:1294-300. (Pubitemid 44706932)
-
(2006)
Nature Medicine
, vol.12
, Issue.11
, pp. 1294-1300
-
-
Potti, A.1
Dressman, H.K.2
Bild, A.3
Riedel, R.F.4
Chan, G.5
Sayer, R.6
Cragun, J.7
Cottrill, H.8
Kelley, M.J.9
Petersen, R.10
Harpole, D.11
Marks, J.12
Berchuck, A.13
Ginsburg, G.S.14
Febbo, P.15
Lancaster, J.16
Nevins, J.R.17
-
107
-
-
20144389741
-
Gene expression profiles predict early relapse in ovarian cancer after platinum-paclitaxel chemotherapy
-
Hartmann LC, Lu KH, Linette GP, et al. Gene expression profiles predict early relapse in ovarian cancer after platinum-paclitaxel chemotherapy. Clin Cancer Res 2005;11:2149-55.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2149-2155
-
-
Hartmann, L.C.1
Lu, K.H.2
Linette, G.P.3
-
108
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006;6:857-66.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
109
-
-
72649084669
-
Differential expression profiling of microRNAs and their potential involvement in renal cell carcinoma pathogenesis
-
Chow TF, Youssef YM, Lianidou E, et al. Differential expression profiling of microRNAs and their potential involvement in renal cell carcinoma pathogenesis. Clin Biochem 2010;43:150-8.
-
(2010)
Clin Biochem
, vol.43
, pp. 150-158
-
-
Chow, T.F.1
Youssef, Y.M.2
Lianidou, E.3
-
111
-
-
70349098023
-
MicroRNAs in clinical oncology: At the crossroads between promises and problems
-
Metias SM, Lianidou E, Yousef GM. MicroRNAs in clinical oncology: at the crossroads between promises and problems. J Clin Pathol 2009;62:771-6.
-
(2009)
J Clin Pathol
, vol.62
, pp. 771-776
-
-
Metias, S.M.1
Lianidou, E.2
Yousef, G.M.3
-
112
-
-
74049163692
-
Diagnostic and prognostic implications of microRNA profiling in prostate carcinoma
-
Schaefer A, Jung M, Mollenkopf HJ, et al. Diagnostic and prognostic implications of microRNA profiling in prostate carcinoma. Int J Cancer 2010;126:1166-76.
-
(2010)
Int J Cancer
, vol.126
, pp. 1166-1176
-
-
Schaefer, A.1
Jung, M.2
Mollenkopf, H.J.3
-
113
-
-
67651002343
-
Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell
-
Sotiropoulou G, Pampalakis G, Lianidou E, Mourelatos Z. Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. RNA 2009;15:1443-61.
-
(2009)
RNA
, vol.15
, pp. 1443-1461
-
-
Sotiropoulou, G.1
Pampalakis, G.2
Lianidou, E.3
Mourelatos, Z.4
-
114
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M. Epigenetics in cancer. N Engl J Med 2008;358:1148-59.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
116
-
-
57249105121
-
Investigating the correspondence between transcriptomic and proteomic expression profiles using coupled cluster models
-
Rogers S, Girolami M, Kolch W, et al. Investigating the correspondence between transcriptomic and proteomic expression profiles using coupled cluster models. Bioinformatics 2008;24:2894-900.
-
(2008)
Bioinformatics
, vol.24
, pp. 2894-2900
-
-
Rogers, S.1
Girolami, M.2
Kolch, W.3
-
118
-
-
33645083180
-
Protein chip based miniaturized assay for the simultaneous quantitative monitoring of cancer biomarkers in tissue extracts
-
Weissenstein U, Schneider MJ, Pawlak M, et al. Protein chip based miniaturized assay for the simultaneous quantitative monitoring of cancer biomarkers in tissue extracts. Proteomics 2006;6:1427-36.
-
(2006)
Proteomics
, vol.6
, pp. 1427-1436
-
-
Weissenstein, U.1
Schneider, M.J.2
Pawlak, M.3
-
119
-
-
33744915787
-
Biomarker discovery for ovarian cancer using SELDI-TOF-MS
-
Zhang H, Kong B, Qu X, Jia L, Deng B, Yang Q. Biomarker discovery for ovarian cancer using SELDI-TOF-MS. Gynecol Oncol 2006;102:61-6.
-
(2006)
Gynecol Oncol
, vol.102
, pp. 61-66
-
-
Zhang, H.1
Kong, B.2
Qu, X.3
Jia, L.4
Deng, B.5
Yang, Q.6
-
120
-
-
0037250740
-
Antibody microarray profiling of human prostate cancer sera: Antibody screening and identification of potential biomarkers
-
DOI 10.1002/pmic.200390009
-
Miller JC, Zhou H, Kwekel J, et al. Antibody microarray profiling of human prostate cancer sera: antibody screening and identification of potential biomarkers. Proteomics 2003;3:56-63. (Pubitemid 36151068)
-
(2003)
Proteomics
, vol.3
, Issue.1
, pp. 56-63
-
-
Miller, J.C.1
Zhou, H.2
Kwekel, J.3
Cavallo, R.4
Burke, J.5
Butler, E.B.6
Teh, B.S.7
Haab, B.B.8
-
121
-
-
59949086822
-
Exploring the pathogenesis of renal cell carcinoma: Pathway and bioinformatics analysis of dysregulated genes and proteins
-
Romaschin AD, Youssef Y, Chow TF, et al. Exploring the pathogenesis of renal cell carcinoma: pathway and bioinformatics analysis of dysregulated genes and proteins. Biol Chem 2009;390:125-35.
-
(2009)
Biol Chem
, vol.390
, pp. 125-135
-
-
Romaschin, A.D.1
Youssef, Y.2
Chow, T.F.3
-
122
-
-
68549106345
-
Differential protein expressions in renal cell carcinoma: New biomarker discovery by mass spectrometry
-
Siu KW, DeSouza LV, Scorilas A, et al. Differential protein expressions in renal cell carcinoma: new biomarker discovery by mass spectrometry. J Proteome Res 2009;8:3797-807.
-
(2009)
J Proteome Res
, vol.8
, pp. 3797-3807
-
-
Siu, K.W.1
DeSouza, L.V.2
Scorilas, A.3
-
123
-
-
72449200207
-
Membrane proteomics for leukemia classification and drug target identification
-
Kohnke PL, Mulligan SP, Christopherson RI. Membrane proteomics for leukemia classification and drug target identification. Curr Opin Mol Ther 2009;11:603-10.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 603-610
-
-
Kohnke, P.L.1
Mulligan, S.P.2
Christopherson, R.I.3
-
124
-
-
26444490100
-
Studying cellular processes and detecting disease with protein microarrays
-
Zangar RC, Varnum SM, Bollinger N. Studying cellular processes and detecting disease with protein microarrays. Drug Metab Rev 2005;37:473-87.
-
(2005)
Drug Metab Rev
, vol.37
, pp. 473-487
-
-
Zangar, R.C.1
Varnum, S.M.2
Bollinger, N.3
-
125
-
-
33646709877
-
Technology insight: Pharmacoproteomics for cancer-promises of patient-tailored medicine using protein microarrays
-
Wulfkuhle JD, Edmiston KH, Liotta LA, Petricoin EF III. Technology insight: pharmacoproteomics for cancer-promises of patient-tailored medicine using protein microarrays. Nat Clin Pract Oncol 2006;3:256-68.
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 256-268
-
-
Wulfkuhle, J.D.1
Edmiston, K.H.2
Liotta, L.A.3
Petricoin III, E.F.4
-
127
-
-
25144500611
-
Human Cancer Genome Project moving forward despite some doubts in community
-
Garber K. Human Cancer Genome Project moving forward despite some doubts in community. J Natl Cancer Inst 2005;97:1322-4.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1322-1324
-
-
Garber, K.1
-
128
-
-
61349163553
-
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1
-
Zheng W, Long J, Gao YT, et al. Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat Genet 2009;41:324-8.
-
(2009)
Nat Genet
, vol.41
, pp. 324-328
-
-
Zheng, W.1
Long, J.2
Gao, Y.T.3
-
129
-
-
34247548755
-
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
-
Yeager M, Orr N, Hayes RB, et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet 2007;39:645-9.
-
(2007)
Nat Genet
, vol.39
, pp. 645-649
-
-
Yeager, M.1
Orr, N.2
Hayes, R.B.3
-
130
-
-
70349540906
-
Identification of a new prostate cancer susceptibility locus on chromosome 8q24
-
Yeager M, Chatterjee N, Ciampa J, et al. Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet 2009;41:1055-7.
-
(2009)
Nat Genet
, vol.41
, pp. 1055-1057
-
-
Yeager, M.1
Chatterjee, N.2
Ciampa, J.3
-
131
-
-
72149129508
-
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma
-
Landi MT, Chatterjee N, Yu K, et al. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet 2009;85:679-91.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 679-691
-
-
Landi, M.T.1
Chatterjee, N.2
Yu, K.3
-
132
-
-
69349102630
-
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2
-
Song H, Ramus SJ, Tyrer J, et al. A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet 2009;41:996-1000.
-
(2009)
Nat Genet
, vol.41
, pp. 996-1000
-
-
Song, H.1
Ramus, S.J.2
Tyrer, J.3
-
133
-
-
77952382817
-
Genome-wide examination of genetic variants associated with response to platinum-based chemotherapy in patients with small-cell lung cancer
-
Wu C, Xu B, Yuan P, et al. Genome-wide examination of genetic variants associated with response to platinum-based chemotherapy in patients with small-cell lung cancer. Pharmacogenet Genomics 2010;20:389-95.
-
(2010)
Pharmacogenet Genomics
, vol.20
, pp. 389-395
-
-
Wu, C.1
Xu, B.2
Yuan, P.3
-
134
-
-
77956525903
-
Genome wide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma
-
Epub ahead of print
-
Leshchenko VV, Kuo PY, Shaknovich R, et al. Genome wide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. Blood. Epub ahead of print 2010.
-
(2010)
Blood
-
-
Leshchenko, V.V.1
Kuo, P.Y.2
Shaknovich, R.3
-
135
-
-
70249134919
-
Molecular networks as sensors and drivers of common human diseases
-
Schadt EE. Molecular networks as sensors and drivers of common human diseases. Nature 2009;461:218-23.
-
(2009)
Nature
, vol.461
, pp. 218-223
-
-
Schadt, E.E.1
-
137
-
-
23044466543
-
The interactive online SKY/MFISH and CGH database and the Entrez cancer chromosomes search database: Linkage of chromosomal aberrations with the genome sequence
-
Knutsen T, Gobu V, Knaus R, et al. The interactive online SKY/MFISH and CGH database and the Entrez cancer chromosomes search database: linkage of chromosomal aberrations with the genome sequence. Genes Chromosomes Cancer 2005;44:52-64.
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 52-64
-
-
Knutsen, T.1
Gobu, V.2
Knaus, R.3
-
138
-
-
58149199563
-
Implementation of Gene-Pattern within the Stanford Microarray Database
-
Hubble J, Demeter J, Jin H, et al. Implementation of Gene-Pattern within the Stanford Microarray Database. Nucleic Acids Res 2009;37:D898-901.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Hubble, J.1
Demeter, J.2
Jin, H.3
-
139
-
-
77950395254
-
The Roche Cancer Genome Database (RCGDB)
-
Kuntzer J, Eggle D, Lenhof HP, Burtscher H, Klostermann S. The Roche Cancer Genome Database (RCGDB). Hum Mutat 2010;31:407-13.
-
(2010)
Hum Mutat
, vol.31
, pp. 407-413
-
-
Kuntzer, J.1
Eggle, D.2
Lenhof, H.P.3
Burtscher, H.4
Klostermann, S.5
-
142
-
-
77950440741
-
Has the revolution arrived?
-
Collins F. Has the revolution arrived? Nature 2010;464:674-5.
-
(2010)
Nature
, vol.464
, pp. 674-675
-
-
Collins, F.1
-
143
-
-
34248197651
-
Basal-like phenotype is not associated with patient survival in estrogen- Receptor-negative breast cancers
-
Jumppanen M, Gruvberger-Saal S, Kauraniemi P, et al. Basal-like phenotype is not associated with patient survival in estrogen- receptor-negative breast cancers. Breast Cancer Res 2007;9:R16.
-
(2007)
Breast Cancer Res
, vol.9
-
-
Jumppanen, M.1
Gruvberger-Saal, S.2
Kauraniemi, P.3
-
144
-
-
77950456427
-
Multiple personal genomes await
-
Venter JC. Multiple personal genomes await. Nature 2010;464:676-7.
-
(2010)
Nature
, vol.464
, pp. 676-677
-
-
Venter, J.C.1
-
145
-
-
74749106342
-
Novel clinico-genome network modeling for revolutionizing genotype-phenotype-based personalized cancer care
-
Roukos DH. Novel clinico-genome network modeling for revolutionizing genotype-phenotype-based personalized cancer care. Expert Rev Mol Diagn 2010;10:33-48.
-
(2010)
Expert Rev Mol Diagn
, vol.10
, pp. 33-48
-
-
Roukos, D.H.1
-
146
-
-
77949613884
-
Systems medicine: A real approach for future personalized oncology?
-
Roukos DH. Systems medicine: a real approach for future personalized oncology? Pharmacogenomics 2010;11:283-7.
-
(2010)
Pharmacogenomics
, vol.11
, pp. 283-287
-
-
Roukos, D.H.1
-
147
-
-
77950607162
-
Bionetworks-based personalized medicine versus comparative-effectiveness research or harmonization of both in cancer management?
-
Roukos DH. Bionetworks-based personalized medicine versus comparative-effectiveness research or harmonization of both in cancer management? Expert Rev Mol Diagn 2010;10:247-50.
-
(2010)
Expert Rev Mol Diagn
, vol.10
, pp. 247-250
-
-
Roukos, D.H.1
-
148
-
-
34250001297
-
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
-
Hunter DJ, Kraft P, Jacobs KB, et al. A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet 2007;39:870-4.
-
(2007)
Nat Genet
, vol.39
, pp. 870-874
-
-
Hunter, D.J.1
Kraft, P.2
Jacobs, K.B.3
-
149
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjoblom T, Jones S, Wood LD, et al. The consensus coding sequences of human breast and colorectal cancers. Science 2006;314:268-74.
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
-
150
-
-
77951115122
-
International network of cancer genome projects
-
International network of cancer genome projects. Nature 2010;464:993-8.
-
(2010)
Nature
, vol.464
, pp. 993-998
-
-
-
151
-
-
42549089637
-
Biologists initiate plan to map human proteome
-
DOI 10.1038/452920a, PII 452920A
-
Pearson H. Biologists initiate plan to map human proteome. Nature 2008;452:920-1. (Pubitemid 351589594)
-
(2008)
Nature
, vol.452
, Issue.7190
, pp. 920-921
-
-
Pearson, H.1
|