Genome-wide analysis of survival in early-stage non-small-cell lung cancer

Journal of Clinical Oncology

Volumn 27, Issue 16, 2009, Pages 2660-2667

  Huang, Yen Tsung ^a   Heist, Rebecca S ^a   Chirieac, Lucian R ^a   Lin, Xihong ^a   Skaug, Vidar ^a   Zienolddiny, Shanbeh ^a   Haugen, Aage ^a   Wu, Michael C ^a   Wang, Zhaoxi ^a   Su, Li ^a   Asomaning, Kofi ^a   Christiani, David C ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ALLELE; ARTICLE; CANCER MORTALITY; CANCER STAGING; CANCER SURVIVAL; CHROMOSOME 3Q; CHROMOSOME 5P; CHROMOSOME 8Q; CONTROLLED STUDY; DNA EXTRACTION; FEMALE; GENOME ANALYSIS; GENOTYPE; HUMAN; LUNG NON SMALL CELL CANCER; LUNG PARENCHYMA; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL HEALTH; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; CHROMOSOME 3; CHROMOSOME 5; CHROMOSOME 8; CLINICAL TRIAL; COHORT ANALYSIS; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; KAPLAN MEIER METHOD; LUNG TUMOR; METHODOLOGY; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; NORWAY; PATHOLOGY; PREDICTION AND FORECASTING; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; REPRODUCIBILITY; RISK ASSESSMENT; RISK FACTOR; TIME; UNITED STATES; VALIDATION STUDY;

A2BP1 PROTEIN, HUMAN; CADHERIN; EYA2 PROTEIN, HUMAN; NUCLEAR PROTEIN; PCDH7 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE PHOSPHATASE; RNA BINDING PROTEIN; SIGNAL PEPTIDE; STK39 PROTEIN, HUMAN; TUMOR MARKER;

AGED; CADHERINS; CARCINOMA, NON-SMALL-CELL LUNG; CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 5; CHROMOSOMES, HUMAN, PAIR 8; COHORT STUDIES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KAPLAN-MEIERS ESTIMATE; LUNG NEOPLASMS; MALE; MASSACHUSETTS; MIDDLE AGED; NEOPLASM STAGING; NORWAY; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROTEIN TYROSINE PHOSPHATASES; PROTEIN-SERINE-THREONINE KINASES; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; RISK FACTORS; RNA-BINDING PROTEINS; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 66849130885     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2008.18.7906     Document Type: Article

References (28)

1. Jemal A, Siegel R, Ward E, et al: Cancer statistics, 2007. CA Cancer J Clin 57:43-66, 2007
2. Govindan R, Page N, Morgensztern D, et al: Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: Analysis of the surveillance, epidemiologic, and end results database. J Clin Oncol 24:4539-4544, 2006
3. Hoffman PC, Mauer AM, Vokes EE: Lung cancer. Lancet 355:479-485, 2000
4. Hung RJ, McKay JD, Gaborieau V, et al: A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452:633-637, 2008
5. Amos CI, Wu X, Broderick P, et al: Genomewide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet 40:616-622, 2008
6. Ninomiya H, Nomura K, Satoh Y, et al: Genetic instability in lung cancer: Concurrent analysis of chromosomal, mini- and microsatellite instability and loss of heterozygosity. Br J Cancer 94:1485-1491, 2006
7. Kim TM, Yim SH, Lee JS, et al: Genomewide screening of genomic alterations and their clinicopathologic implications in non-small cell lung cancers. Clin Cancer Res 11:8235-8242, 2005
8. Weir BA, Woo MS, Getz G, et al: Characterizing the cancer genome in lung adenocarcinoma. Nature 450:893-898, 2007
9. Kim MY, Yim SH, Kwon MS, et al: Recurrent genomic alterations with impact on survival in colorectal cancer identified by genome-wide array comparative genomic hybridization. Gastroenterology 131:1913-1924, 2006
10. Potti A, Mukherjee S, Petersen R, et al: A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 355:570-580, 2006
11. Chen HY, Yu SL, Chen CH, et al: A five-gene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med 356:11-20, 2007
12. Torring N, Borre M, Sorensen KD, et al: Genome-wide analysis of allelic imbalance in prostate cancer using the Affymetrix 50K SNP mapping array. Br J Cancer 96:499-506, 2007
13. Lai LA, Paulson TG, Li X, et al: Increasing genomic instability during premalignant neoplastic progression revealed through high resolution array-CGH. Genes Chromosomes Cancer 46:532-542, 2007
14. Koed K, Wiuf C, Christensen LL, et al: High-density single nucleotide polymorphism array defines novel stage and location-dependent allelic imbalances in human bladder tumors. Cancer Res 65:34-45, 2005
15. Zhao X, Li C, Paez JG, et al: An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Res 64:3060-3071, 2004
16. Benjamini Y, Hochberg Y: Controlling the false discovery rate: A practical and powerful approach to multiple testing. J Roy Statist Soc Ser B 57:289-300, 1995
17. Johnston AM, Naselli G, Gonez LJ, et al: SPAK, a STE20/SPS1-related kinase that activates the p38 pathway. Oncogene 19:4290-4297, 2000
18. Polek TC, Talpaz M, Spivak-Kroizman TR: TRAIL-induced cleavage and inactivation of SPAK sensitizes cells to apoptosis. Biochem Biophys Res Commun 349:1016-1024, 2006
19. Yoshida K: Fibroblast cell shape and adhesion in vitro is altered by overexpression of the 7a and 7b isoforms of protocadherin 7, but not the 7c isoform. Cell Mol Biol Lett 8:735-741, 2003
20. Yoshida K, Yoshitomo-Nakagawa K, Seki N, et al: Cloning, expression analysis, and chromosomal localization of BH-protocadherin (PCDH7), a novel member of the cadherin superfamily. Genomics 49:458-461, 1998
21. Shibata H, Huynh DP, Pulst SM: A novel protein with RNA-binding motifs interacts with ataxin-2. Hum Mol Genet 9:1303-1313, 2000
22. Kiehl TR, Shibata H, Vo T, et al: Identification and expression of a mouse ortholog of A2BP1. Mamm Genome 12:595-601, 2001
23. Clark SW, Fee BE, Cleveland JL: Misexpression of the eyes absent family triggers the apoptotic program. J Biol Chem 277:3560-3567, 2002
24. Zhang L, Yang N, Huang J, et al: Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth. Cancer Res 65:925-932, 2005
25. Lin PI, Vance JM, Pericak-Vance MA, et al: No gene is an island: The flip-flop phenomenon. Am J Hum Genet 80:531-538, 2007
26. Hersh CP, Raby BA, Soto-Quiros ME, et al: Comprehensive testing of positionally cloned asthma genes in two populations. Am J Respir Crit Care Med 176:849-857, 2007
27. Tyner SD, Venkatachalam S, Choi J, et al: p53 mutant mice that display early ageing-associated phenotypes. Nature 415:45-53, 2002
28. Beausejour CM, Campisi J: Ageing: Balancing regeneration and cancer. Nature 443:404-405, 2006