STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: Biological and clinical implications

Oncogene

Volumn 20, Issue 36, 2001, Pages 5054-5058

  Tuveson, David A ^a,b   Willis, Nicholas A ^a   Jacks, Tyler ^a   Griffin, James D ^b   Singer, Samuel ^b   Fletcher, Christopher D M ^b   Fletcher, Jonathan A ^b   Demetri, George D ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

C KIT; Gastrointestional Stromal Tumors(GIST); STI571

Indexed keywords

IMATINIB; ONCOPROTEIN; PROTEIN TYROSINE KINASE INHIBITOR; STEM CELL FACTOR;

AMINO ACID SUBSTITUTION; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; GASTROINTESTINAL TUMOR; HUMAN; HUMAN CELL; MISSENSE MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STROMA;

APOPTOSIS; CELL DIVISION; ENZYME INHIBITORS; GASTROINTESTINAL NEOPLASMS; HUMANS; MUTATION; ONCOGENE PROTEINS; PIPERAZINES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-KIT; PYRIMIDINES; STROMAL CELLS; TUMOR CELLS, CULTURED;

EID: 0035899418     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1204704     Document Type: Article

References (30)