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Volumn 28, Issue 6, 2010, Pages 757-763

Bio and nanotechnological strategies for tumor-targeted gene therapy

Author keywords

Cationic polymer; Gene delivery; Gene therapy; Intracellular signal; Peptide substrate

Indexed keywords

ANGIOGENIC TUMOR; CATIONIC POLYMERS; ENHANCED PERMEABILITY AND RETENTION EFFECTS; GENE DELIVERY; GENE DELIVERY SYSTEMS; INTRACELLULAR SIGNALS; PEPTIDE SUBSTRATE; THERAPEUTIC GENES; TUMOR CELLS;

EID: 77957021160     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2010.06.001     Document Type: Review
Times cited : (23)

References (84)
  • 2
    • 70849106158 scopus 로고    scopus 로고
    • Specific transgene expression in HIV-infected cells using protease-cleavable transcription regulator
    • Asai D., Kuramoto M., Shoji Y., Kang J.H., Kodama K.B., Kawamura K., et al. Specific transgene expression in HIV-infected cells using protease-cleavable transcription regulator. J Control Release 2010, 141:52-61.
    • (2010) J Control Release , vol.141 , pp. 52-61
    • Asai, D.1    Kuramoto, M.2    Shoji, Y.3    Kang, J.H.4    Kodama, K.B.5    Kawamura, K.6
  • 3
    • 68949211766 scopus 로고    scopus 로고
    • Inflammatory cell-specific transgene expression system responding to Iκ-B kinase beta activation
    • Asai D., Tsuchiya A., Kang J.H., Kawamura K., Oishi J., Mori T., et al. Inflammatory cell-specific transgene expression system responding to Iκ-B kinase beta activation. J Gene Med 2009, 11:624-632.
    • (2009) J Gene Med , vol.11 , pp. 624-632
    • Asai, D.1    Tsuchiya, A.2    Kang, J.H.3    Kawamura, K.4    Oishi, J.5    Mori, T.6
  • 4
    • 3442901916 scopus 로고    scopus 로고
    • Sigma receptors and cancer: possible involvement of ion channels
    • Aydar E., Palmer C.P., Djamgoz M.B.A. Sigma receptors and cancer: possible involvement of ion channels. Cancer Res 2004, 64:5029-5035.
    • (2004) Cancer Res , vol.64 , pp. 5029-5035
    • Aydar, E.1    Palmer, C.P.2    Djamgoz, M.B.A.3
  • 5
    • 33747141012 scopus 로고    scopus 로고
    • The use of clostridial spores for cancer treatment
    • Barbé S., van Mellaert L., Anné J. The use of clostridial spores for cancer treatment. J Appl Microbiol 2006, 101:571-578.
    • (2006) J Appl Microbiol , vol.101 , pp. 571-578
    • Barbé, S.1    van Mellaert, L.2    Anné, J.3
  • 6
    • 34548267667 scopus 로고    scopus 로고
    • Endocytic mechanisms for targeted drug delivery
    • Bareford L.M., Swaan P.W. Endocytic mechanisms for targeted drug delivery. Adv Drug Deliv Rev 2007, 59:748-758.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 748-758
    • Bareford, L.M.1    Swaan, P.W.2
  • 7
    • 0345357073 scopus 로고    scopus 로고
    • Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery
    • Bellocq N.C., Pun S.H., Jensen G.S., Davis M.E. Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery. Bioconjug Chem 2003, 14:1122-1132.
    • (2003) Bioconjug Chem , vol.14 , pp. 1122-1132
    • Bellocq, N.C.1    Pun, S.H.2    Jensen, G.S.3    Davis, M.E.4
  • 8
    • 37849014587 scopus 로고    scopus 로고
    • Modification of adenovirus capsid with a designed protein ligand yields a gene vector targeted to a major molecular marker of cancer
    • Belousova N., Mikheeva G., Gelovani J., Krasnykh V. Modification of adenovirus capsid with a designed protein ligand yields a gene vector targeted to a major molecular marker of cancer. J Virol 2007, 82:630-637.
    • (2007) J Virol , vol.82 , pp. 630-637
    • Belousova, N.1    Mikheeva, G.2    Gelovani, J.3    Krasnykh, V.4
  • 10
    • 58149185339 scopus 로고    scopus 로고
    • Tumor-targeted delivery of siRNA by non-viral vector: safe and effective cancer therapy
    • Chen Y., Huang L. Tumor-targeted delivery of siRNA by non-viral vector: safe and effective cancer therapy. Expert Opin Drug Deliv 2008, 5:1301-1311.
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 1301-1311
    • Chen, Y.1    Huang, L.2
  • 11
    • 67249131198 scopus 로고    scopus 로고
    • Novel cationic lipid that delivers siRNA and enhances therapeutic effect in lung cancer cells
    • Chen Y., Sen J., Bathula S.R., Yang Q., Fittipaldi R., Huang L. Novel cationic lipid that delivers siRNA and enhances therapeutic effect in lung cancer cells. Mol Pharm 2009, 6:696-705.
    • (2009) Mol Pharm , vol.6 , pp. 696-705
    • Chen, Y.1    Sen, J.2    Bathula, S.R.3    Yang, Q.4    Fittipaldi, R.5    Huang, L.6
  • 12
    • 7044233630 scopus 로고    scopus 로고
    • Oncolytic effects of adenovirus mutant capable of replicating in hypoxic and normoxic regions of solid tumor
    • Cho W.K., Seong Y.R., Lee Y.H., Kim M.J., Hwang K.S., Yoo J., et al. Oncolytic effects of adenovirus mutant capable of replicating in hypoxic and normoxic regions of solid tumor. Mol Ther 2004, 10:938-949.
    • (2004) Mol Ther , vol.10 , pp. 938-949
    • Cho, W.K.1    Seong, Y.R.2    Lee, Y.H.3    Kim, M.J.4    Hwang, K.S.5    Yoo, J.6
  • 13
    • 52049121804 scopus 로고    scopus 로고
    • An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor
    • Chono S., Li S.D., Conwell C.C., Huang L. An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor. J Control Release 2008, 131:64-69.
    • (2008) J Control Release , vol.131 , pp. 64-69
    • Chono, S.1    Li, S.D.2    Conwell, C.C.3    Huang, L.4
  • 14
    • 67650351062 scopus 로고    scopus 로고
    • Nuclear targeting of viral and non-viral DNA
    • Chowdhury E.H. Nuclear targeting of viral and non-viral DNA. Expert Opin Drug Deliv 2009, 6:697-703.
    • (2009) Expert Opin Drug Deliv , vol.6 , pp. 697-703
    • Chowdhury, E.H.1
  • 17
    • 0034114282 scopus 로고    scopus 로고
    • Vascular permeability in a human tumour xenograft: molecular charge dependence
    • Dellian M., Yuan F., Trubetskoy V.S. Vascular permeability in a human tumour xenograft: molecular charge dependence. Br J Cancer 2000, 82:1513-1518.
    • (2000) Br J Cancer , vol.82 , pp. 1513-1518
    • Dellian, M.1    Yuan, F.2    Trubetskoy, V.S.3
  • 18
    • 59449091692 scopus 로고    scopus 로고
    • In vivo targeted gene delivery by cationic nanoparticles for treatment of hepatocellular carcinoma
    • Díez S., Navarro G., de Ilarduya C.T. In vivo targeted gene delivery by cationic nanoparticles for treatment of hepatocellular carcinoma. J Gene Med 2009, 11:38-45.
    • (2009) J Gene Med , vol.11 , pp. 38-45
    • Díez, S.1    Navarro, G.2    de Ilarduya, C.T.3
  • 19
    • 63849300752 scopus 로고    scopus 로고
    • Application of RGD-containing peptides as imaging probes for αvβ3 expression
    • Dijkgraaf I., Beer A.J., Wester H.J. Application of RGD-containing peptides as imaging probes for αvβ3 expression. Front Biosci 2009, 14:887-899.
    • (2009) Front Biosci , vol.14 , pp. 887-899
    • Dijkgraaf, I.1    Beer, A.J.2    Wester, H.J.3
  • 20
    • 33644772618 scopus 로고    scopus 로고
    • Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers
    • Dreher M.R., Liu W., Michelich C.R. Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers. J Natl Cancer Inst 2006, 98:335-344.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 335-344
    • Dreher, M.R.1    Liu, W.2    Michelich, C.R.3
  • 21
    • 25844524902 scopus 로고    scopus 로고
    • Polymer-drug conjugates: towards a novel approach for the treatment of endocrine-related cancer
    • Duncan D., Vicent M.J., Greco F., Nicholson R.I. Polymer-drug conjugates: towards a novel approach for the treatment of endocrine-related cancer. Endocr-Relat Cancer 2005, 12:S189-S199.
    • (2005) Endocr-Relat Cancer , vol.12
    • Duncan, D.1    Vicent, M.J.2    Greco, F.3    Nicholson, R.I.4
  • 22
    • 67749122122 scopus 로고    scopus 로고
    • Targeting PI3K signaling in cancer: opportunities, challenges and limitations
    • Engelman J.A. Targeting PI3K signaling in cancer: opportunities, challenges and limitations. Nat Rev Cancer 2009, 9:550-562.
    • (2009) Nat Rev Cancer , vol.9 , pp. 550-562
    • Engelman, J.A.1
  • 23
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: an organizing principle for drug discovery?
    • Folkman J. Angiogenesis: an organizing principle for drug discovery?. Nat Rev Drug Discov 2007, 6:237-286.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 237-286
    • Folkman, J.1
  • 24
    • 0030448814 scopus 로고    scopus 로고
    • Blood vessel formation: what is its molecular basis?
    • Folkman J., D'Amore P.A. Blood vessel formation: what is its molecular basis?. Cell 1996, 87:1153-1155.
    • (1996) Cell , vol.87 , pp. 1153-1155
    • Folkman, J.1    D'Amore, P.A.2
  • 25
    • 40549116345 scopus 로고    scopus 로고
    • Retargeting polymer-coated adenovirus to the FGF receptor allows productive infection and mediates efficacy in a peritoneal model of human ovarian cancer
    • Green N.K., Morrison J., Hale S., Briggs S.S., Stevenson M., Subr V., et al. Retargeting polymer-coated adenovirus to the FGF receptor allows productive infection and mediates efficacy in a peritoneal model of human ovarian cancer. J Gene Med 2008, 10:280-289.
    • (2008) J Gene Med , vol.10 , pp. 280-289
    • Green, N.K.1    Morrison, J.2    Hale, S.3    Briggs, S.S.4    Stevenson, M.5    Subr, V.6
  • 26
    • 21744451618 scopus 로고    scopus 로고
    • Folate-linked lipid-based nanoparticle for targeted gene delivery
    • Hattori Y., Maitani Y. Folate-linked lipid-based nanoparticle for targeted gene delivery. Curr Drug Deliv 2005, 2:243-252.
    • (2005) Curr Drug Deliv , vol.2 , pp. 243-252
    • Hattori, Y.1    Maitani, Y.2
  • 27
    • 0032516078 scopus 로고    scopus 로고
    • Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment
    • Hobbs S.K., Monsky W.L., Yuan F. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci USA 1998, 95:4607-4612.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4607-4612
    • Hobbs, S.K.1    Monsky, W.L.2    Yuan, F.3
  • 28
    • 1542619344 scopus 로고    scopus 로고
    • Protein kinase C isozymes as potential targets for anticancer therapy
    • Hofmann J. Protein kinase C isozymes as potential targets for anticancer therapy. Curr Cancer Drug Targets 2004, 4:125-146.
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 125-146
    • Hofmann, J.1
  • 29
  • 30
    • 57349097756 scopus 로고    scopus 로고
    • Design of polymeric carriers for cancer-specific gene targeting: utilization of abnormal protein kinase Cα activation in cancer cells
    • Kang J.H., Asai D., Kim J.H., Mori T., Toita R., Tomiyama T., et al. Design of polymeric carriers for cancer-specific gene targeting: utilization of abnormal protein kinase Cα activation in cancer cells. J Am Chem Soc 2008, 130:14906-14907.
    • (2008) J Am Chem Soc , vol.130 , pp. 14906-14907
    • Kang, J.H.1    Asai, D.2    Kim, J.H.3    Mori, T.4    Toita, R.5    Tomiyama, T.6
  • 31
    • 44649102706 scopus 로고    scopus 로고
    • A short peptide is a protein kinase C (PKC)α-specific substrate
    • Kang J.H., Asai D., Yamada S., Toita R., Oishi J., Mori T., et al. A short peptide is a protein kinase C (PKC)α-specific substrate. Proteomics 2008, 8:2006-2011.
    • (2008) Proteomics , vol.8 , pp. 2006-2011
    • Kang, J.H.1    Asai, D.2    Yamada, S.3    Toita, R.4    Oishi, J.5    Mori, T.6
  • 32
    • 77955281517 scopus 로고    scopus 로고
    • Hepatoma-targeted gene delivery using a tumor cell-specific gene regulation system combined with a human liver cell-specific bionanocapsule
    • Kang J.H., Oishi J., Kim J.H., Toita R., Oishi J., Mori T., et al. Hepatoma-targeted gene delivery using a tumor cell-specific gene regulation system combined with a human liver cell-specific bionanocapsule. Nanomedicine 2010, 6:583-589.
    • (2010) Nanomedicine , vol.6 , pp. 583-589
    • Kang, J.H.1    Oishi, J.2    Kim, J.H.3    Toita, R.4    Oishi, J.5    Mori, T.6
  • 33
    • 71749091872 scopus 로고    scopus 로고
    • Cellular signal-specific peptide substrate is essential for the gene delivery system responding to cellular signals
    • Kang J.H., Toita R., Tomiyama T., Oishi J., Asai D., Mori T., et al. Cellular signal-specific peptide substrate is essential for the gene delivery system responding to cellular signals. Bioorg Med Chem Lett 2009, 19:6082-6086.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 6082-6086
    • Kang, J.H.1    Toita, R.2    Tomiyama, T.3    Oishi, J.4    Asai, D.5    Mori, T.6
  • 34
    • 0036737484 scopus 로고    scopus 로고
    • Intracellular signal-responsive artificial gene regulation for novel gene delivery
    • Katayama Y., Fujii K., Ito E., Skakihara S., Sonoda T., Murata M., et al. Intracellular signal-responsive artificial gene regulation for novel gene delivery. Biomacromolecules 2002, 3:905-909.
    • (2002) Biomacromolecules , vol.3 , pp. 905-909
    • Katayama, Y.1    Fujii, K.2    Ito, E.3    Skakihara, S.4    Sonoda, T.5    Murata, M.6
  • 35
    • 16344394392 scopus 로고    scopus 로고
    • Intracellular signal-responsive gene carrier for cell-specific gene expression
    • Kawamura K., Oishi J., Kang J.H., Kodama K., Sonoda T., Murata M., et al. Intracellular signal-responsive gene carrier for cell-specific gene expression. Biomacromolecules 2005, 6:908-913.
    • (2005) Biomacromolecules , vol.6 , pp. 908-913
    • Kawamura, K.1    Oishi, J.2    Kang, J.H.3    Kodama, K.4    Sonoda, T.5    Murata, M.6
  • 36
    • 33745204461 scopus 로고    scopus 로고
    • The role of folate receptor ? in cancer development, progression and treatment: cause, consequence or innocent bystander?
    • Kelemen L.E. The role of folate receptor ? in cancer development, progression and treatment: cause, consequence or innocent bystander?. Int J Cancer 2006, 119:243-250.
    • (2006) Int J Cancer , vol.119 , pp. 243-250
    • Kelemen, L.E.1
  • 37
    • 33644593889 scopus 로고    scopus 로고
    • Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery
    • Khalil I.A., Kogure K., Akita H., Harashima H. Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol Rev 2006, 58:32-45.
    • (2006) Pharmacol Rev , vol.58 , pp. 32-45
    • Khalil, I.A.1    Kogure, K.2    Akita, H.3    Harashima, H.4
  • 39
    • 34548409638 scopus 로고    scopus 로고
    • Receptor-mediated delivery by folate-PEF-baculovirus in vitro
    • Kim Y.K., Choi J.Y., Yoo M.K., Jiang H.L., Arote R., Je Y.H., et al. Receptor-mediated delivery by folate-PEF-baculovirus in vitro. J Biotechnol 2007, 131:353-361.
    • (2007) J Biotechnol , vol.131 , pp. 353-361
    • Kim, Y.K.1    Choi, J.Y.2    Yoo, M.K.3    Jiang, H.L.4    Arote, R.5    Je, Y.H.6
  • 40
    • 34547153677 scopus 로고    scopus 로고
    • An acetal-based PEGylation reagent for pH-sensitive shielding of DNA polyplexes
    • Knorr V., Allmendinger L., Walker G.F., Paintner F.F., Wagner E. An acetal-based PEGylation reagent for pH-sensitive shielding of DNA polyplexes. Bioconjug Chem 2007, 18:1218-1225.
    • (2007) Bioconjug Chem , vol.18 , pp. 1218-1225
    • Knorr, V.1    Allmendinger, L.2    Walker, G.F.3    Paintner, F.F.4    Wagner, E.5
  • 41
    • 57349184166 scopus 로고    scopus 로고
    • Self-assembling micelle-like nanoparticles based on phospholipide-polyethyleneimine conjugates for systemic gene delivery
    • Ko Y.T., Kale A., Hartner W.C., Papahadjopoulos-Sternberg B., Trochillin V.P. Self-assembling micelle-like nanoparticles based on phospholipide-polyethyleneimine conjugates for systemic gene delivery. J Control Release 2009, 133:132-138.
    • (2009) J Control Release , vol.133 , pp. 132-138
    • Ko, Y.T.1    Kale, A.2    Hartner, W.C.3    Papahadjopoulos-Sternberg, B.4    Trochillin, V.P.5
  • 43
    • 0042199037 scopus 로고    scopus 로고
    • Targeting adenoviral vectors using heterofunctional polyethylene glycol FGF2 conjugates
    • Lanciotti J., Song A., Doukas J., Sosnowski B., Pierce G., Gregory R., et al. Targeting adenoviral vectors using heterofunctional polyethylene glycol FGF2 conjugates. Mol Ther 2003, 8:99-107.
    • (2003) Mol Ther , vol.8 , pp. 99-107
    • Lanciotti, J.1    Song, A.2    Doukas, J.3    Sosnowski, B.4    Pierce, G.5    Gregory, R.6
  • 44
    • 4444231342 scopus 로고    scopus 로고
    • Poly(N-vinylpyrrolidone)-block-poly(d, l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation
    • Le Garrec D., Gori S., Luo L., Lessard D., Smith D.C., Yessine M.A., et al. Poly(N-vinylpyrrolidone)-block-poly(d, l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation. J Control Release 2004, 99:83-101.
    • (2004) J Control Release , vol.99 , pp. 83-101
    • Le Garrec, D.1    Gori, S.2    Luo, L.3    Lessard, D.4    Smith, D.C.5    Yessine, M.A.6
  • 45
    • 28744436511 scopus 로고    scopus 로고
    • Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics
    • Li Z., Zhao R., Wu X. Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics. FASEB J 2005, 19:1978-1985.
    • (2005) FASEB J , vol.19 , pp. 1978-1985
    • Li, Z.1    Zhao, R.2    Wu, X.3
  • 46
    • 0032927753 scopus 로고    scopus 로고
    • Lipid A mutant Salmonella with suppressed virulence and TNFα induction retain tumor-targeting in vivo
    • Low K.B., Ittensohn M., Le T., Platt J., Sodi S., Amoss M., et al. Lipid A mutant Salmonella with suppressed virulence and TNFα induction retain tumor-targeting in vivo. Nat Biotechnol 1999, 17:37-41.
    • (1999) Nat Biotechnol , vol.17 , pp. 37-41
    • Low, K.B.1    Ittensohn, M.2    Le, T.3    Platt, J.4    Sodi, S.5    Amoss, M.6
  • 47
    • 0036803285 scopus 로고    scopus 로고
    • Polyethylene glycol-diacyllipid micelles demonstrate increased accumulation in subcutaneous tumors in mice
    • Lukyanov A.N., Gao Z., Mazzola L., Torchilin V.P. Polyethylene glycol-diacyllipid micelles demonstrate increased accumulation in subcutaneous tumors in mice. Pharm Res 2002, 19:1424-1429.
    • (2002) Pharm Res , vol.19 , pp. 1424-1429
    • Lukyanov, A.N.1    Gao, Z.2    Mazzola, L.3    Torchilin, V.P.4
  • 49
    • 33747762229 scopus 로고    scopus 로고
    • Exploiting the enhanced permeability retention effect for tumor targeting
    • Lyer A.K., Khaled G., Fang J., Maeda H. Exploiting the enhanced permeability retention effect for tumor targeting. Drug Discov Today 2006, 11:812-818.
    • (2006) Drug Discov Today , vol.11 , pp. 812-818
    • Lyer, A.K.1    Khaled, G.2    Fang, J.3    Maeda, H.4
  • 50
    • 34250902930 scopus 로고    scopus 로고
    • Targeting the protein kinase C family: are we there yet?
    • Mackay H.J., Twelves C.J. Targeting the protein kinase C family: are we there yet?. Nat Rev Cancer 2007, 7:554-562.
    • (2007) Nat Rev Cancer , vol.7 , pp. 554-562
    • Mackay, H.J.1    Twelves, C.J.2
  • 51
    • 0037334516 scopus 로고    scopus 로고
    • Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications
    • Maeda H., Fang J., Inutsuka T., Kitamoto Y. Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications. Int Immunopharmacol 2003, 3:319-328.
    • (2003) Int Immunopharmacol , vol.3 , pp. 319-328
    • Maeda, H.1    Fang, J.2    Inutsuka, T.3    Kitamoto, Y.4
  • 53
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer thermotherapy: mechanism of tumor tropic accumulation of proteins and antitumor agent SMANCS
    • Matsumura Y., Maeda H. A new concept for macromolecular therapeutics in cancer thermotherapy: mechanism of tumor tropic accumulation of proteins and antitumor agent SMANCS. Cancer Res 1986, 46:6387-6392.
    • (1986) Cancer Res , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 54
    • 67649218953 scopus 로고    scopus 로고
    • Integrin αvβ3 targeted gene delivery using RGD peptidomimetic conjugated with copolymers of PEGylated poly(ethylene imine)
    • Merkel O.M., Germershaus O., Wada C.K., Tarcha P.J., Merdan T., Kissel T. Integrin αvβ3 targeted gene delivery using RGD peptidomimetic conjugated with copolymers of PEGylated poly(ethylene imine). Bioconjug Chem 2009, 20:1270-1280.
    • (2009) Bioconjug Chem , vol.20 , pp. 1270-1280
    • Merkel, O.M.1    Germershaus, O.2    Wada, C.K.3    Tarcha, P.J.4    Merdan, T.5    Kissel, T.6
  • 55
    • 1842613536 scopus 로고    scopus 로고
    • Clostridia in cancer therapy
    • Minton N.P. Clostridia in cancer therapy. Nat Rev Microbiol 2003, 1:237-242.
    • (2003) Nat Rev Microbiol , vol.1 , pp. 237-242
    • Minton, N.P.1
  • 56
    • 64049106699 scopus 로고    scopus 로고
    • Selective cancer targeting via aberrant behavior of cancer cell-associated glucocorticoid receptor
    • Mukherjee A., Narayan K.P., Pal K., Kumar J.M., Rangaraj N., Kalivendi S.V., et al. Selective cancer targeting via aberrant behavior of cancer cell-associated glucocorticoid receptor. Mol Ther 2009, 17:623-631.
    • (2009) Mol Ther , vol.17 , pp. 623-631
    • Mukherjee, A.1    Narayan, K.P.2    Pal, K.3    Kumar, J.M.4    Rangaraj, N.5    Kalivendi, S.V.6
  • 57
    • 18144403764 scopus 로고    scopus 로고
    • Haloperidol-associated stealth liposomes: a potent carrier for delivering genes to human breast cancer cells
    • Mukherjee A., Prasad T.K., Rao N.M., Banerjee R. Haloperidol-associated stealth liposomes: a potent carrier for delivering genes to human breast cancer cells. J Biol Chem 2005, 280:15619-15627.
    • (2005) J Biol Chem , vol.280 , pp. 15619-15627
    • Mukherjee, A.1    Prasad, T.K.2    Rao, N.M.3    Banerjee, R.4
  • 58
    • 32044464123 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) signaling in cancer
    • Normanno N., De Luca A., Bianco C. Epidermal growth factor receptor (EGFR) signaling in cancer. Gene 2006, 366:2-16.
    • (2006) Gene , vol.366 , pp. 2-16
    • Normanno, N.1    De Luca, A.2    Bianco, C.3
  • 60
    • 29244432184 scopus 로고    scopus 로고
    • An intracellular kinase signal-responsible gene-carrier for cell specific gene therapy
    • Oishi J., Kawamura K., Kang J.H., Kodama K., Sonoda T., Murata M., et al. An intracellular kinase signal-responsible gene-carrier for cell specific gene therapy. J Control Release 2006, 110:431-436.
    • (2006) J Control Release , vol.110 , pp. 431-436
    • Oishi, J.1    Kawamura, K.2    Kang, J.H.3    Kodama, K.4    Sonoda, T.5    Murata, M.6
  • 61
    • 13644254495 scopus 로고    scopus 로고
    • Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells
    • Oishi M., Nagasaki Y., Itaka K., Nishiyama N., Kataoka K. Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells. J Am Chem Soc 2005, 127:1624-1625.
    • (2005) J Am Chem Soc , vol.127 , pp. 1624-1625
    • Oishi, M.1    Nagasaki, Y.2    Itaka, K.3    Nishiyama, N.4    Kataoka, K.5
  • 62
    • 37549019328 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) receptor targeted delivery of PEGylated adenovirus
    • Park J.W., Mok H., Park T.G. Epidermal growth factor (EGF) receptor targeted delivery of PEGylated adenovirus. Biochem Biophys Res Commun 2008, 366:769-774.
    • (2008) Biochem Biophys Res Commun , vol.366 , pp. 769-774
    • Park, J.W.1    Mok, H.2    Park, T.G.3
  • 63
    • 34548379387 scopus 로고    scopus 로고
    • Processive phosphorylation: mechanism and biological importance
    • Patwardhan P., Miller W.T. Processive phosphorylation: mechanism and biological importance. Cell Signal 2007, 19:2218-2226.
    • (2007) Cell Signal , vol.19 , pp. 2218-2226
    • Patwardhan, P.1    Miller, W.T.2
  • 64
    • 34547092699 scopus 로고    scopus 로고
    • Targeted cancer gene therapy using a hypoxia inducible factor-dependent oncolytic adenovirus armed with interleukin-4
    • Post D.E., Sandberg E.M., Kyle M.M., Devi N.S., Brat D.J., Xu Z., et al. Targeted cancer gene therapy using a hypoxia inducible factor-dependent oncolytic adenovirus armed with interleukin-4. Cancer Res 2007, 67:6872-6881.
    • (2007) Cancer Res , vol.67 , pp. 6872-6881
    • Post, D.E.1    Sandberg, E.M.2    Kyle, M.M.3    Devi, N.S.4    Brat, D.J.5    Xu, Z.6
  • 66
    • 16644387358 scopus 로고    scopus 로고
    • Microbial-based therapy of cancer: a new twist to age old practice
    • Punj V., Saint-Dic D., Daghfal S., Kanwar J.R. Microbial-based therapy of cancer: a new twist to age old practice. Cancer Biol Ther 2004, 3:708-714.
    • (2004) Cancer Biol Ther , vol.3 , pp. 708-714
    • Punj, V.1    Saint-Dic, D.2    Daghfal, S.3    Kanwar, J.R.4
  • 67
    • 27444446499 scopus 로고    scopus 로고
    • 17β-estradiol-associated stealth-liposomal delivery of anticancer gene to breast cancer cells
    • Reddy B.S., Banerjee R. 17β-estradiol-associated stealth-liposomal delivery of anticancer gene to breast cancer cells. Angew Chem Int Ed Engl 2005, 44:6723-6727.
    • (2005) Angew Chem Int Ed Engl , vol.44 , pp. 6723-6727
    • Reddy, B.S.1    Banerjee, R.2
  • 68
    • 33947362046 scopus 로고    scopus 로고
    • The folate receptor: what dose it promise in tissue-targeted therapeutics?
    • Salzar M.D., Ratnam M. The folate receptor: what dose it promise in tissue-targeted therapeutics?. Cancer Metastasis Rev 2007, 26:141-152.
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 141-152
    • Salzar, M.D.1    Ratnam, M.2
  • 69
    • 33749072019 scopus 로고    scopus 로고
    • Nuclear signaling by receptor tyrosine kinases: the first robin of spring
    • Schlessinger J., Lemmon M.A. Nuclear signaling by receptor tyrosine kinases: the first robin of spring. Cell 2006, 127:45-48.
    • (2006) Cell , vol.127 , pp. 45-48
    • Schlessinger, J.1    Lemmon, M.A.2
  • 70
    • 70649088695 scopus 로고    scopus 로고
    • Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application
    • Seki T., Fang J., Maeda H. Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application. Cancer Sci 2009, 100:2426-2430.
    • (2009) Cancer Sci , vol.100 , pp. 2426-2430
    • Seki, T.1    Fang, J.2    Maeda, H.3
  • 71
    • 16344396086 scopus 로고    scopus 로고
    • Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin on targeting ability and antitumor effect in vitro and in vivo
    • Shiokawa T., Hattori Y., Kawano K., Ohguchi Y., Kawakami H., Toma K., et al. Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin on targeting ability and antitumor effect in vitro and in vivo. Clin Cancer Res 2005, 11:2018-2025.
    • (2005) Clin Cancer Res , vol.11 , pp. 2018-2025
    • Shiokawa, T.1    Hattori, Y.2    Kawano, K.3    Ohguchi, Y.4    Kawakami, H.5    Toma, K.6
  • 72
    • 0035827339 scopus 로고    scopus 로고
    • A genomic perspective on human proteases
    • Southan C. A genomic perspective on human proteases. FEBS 2001, 498:214-218.
    • (2001) FEBS , vol.498 , pp. 214-218
    • Southan, C.1
  • 73
    • 0037428893 scopus 로고    scopus 로고
    • Histidine kinases and histidine phosphorylated proteins in mammalian cell biology, signal transduction and cancer
    • Steeg P.S., Palmieri D., Ouatas T., Salerno M. Histidine kinases and histidine phosphorylated proteins in mammalian cell biology, signal transduction and cancer. Cancer Lett 2003, 1901-1912.
    • (2003) Cancer Lett , pp. 1901-1912
    • Steeg, P.S.1    Palmieri, D.2    Ouatas, T.3    Salerno, M.4
  • 74
    • 33947242506 scopus 로고    scopus 로고
    • Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via α6-ingegrins
    • Stevenson M., Hale A.B., Hale S.J., Green N.K., Black G., Fisher K.D., et al. Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via α6-ingegrins. Cancer Gene Ther 2007, 14:335-345.
    • (2007) Cancer Gene Ther , vol.14 , pp. 335-345
    • Stevenson, M.1    Hale, A.B.2    Hale, S.J.3    Green, N.K.4    Black, G.5    Fisher, K.D.6
  • 75
    • 1342310842 scopus 로고    scopus 로고
    • Lysosome and lysosome-related organelles responsible for specialized functions in higher organisms with special emphasis on vacuolar-type proton ATPase
    • Sun-Wada G.H., Wada Y., Futai M. Lysosome and lysosome-related organelles responsible for specialized functions in higher organisms with special emphasis on vacuolar-type proton ATPase. Cell Struct Funct 2003, 28:455-463.
    • (2003) Cell Struct Funct , vol.28 , pp. 455-463
    • Sun-Wada, G.H.1    Wada, Y.2    Futai, M.3
  • 76
    • 69949137270 scopus 로고    scopus 로고
    • Protein kinase Cα-specific peptide substrate graft-type copolymer for cancer cell-specific gene regulation systems
    • Toita R., Kang J.H., Kim J.H., Tomiyama T., Mori T., Niidome T., et al. Protein kinase Cα-specific peptide substrate graft-type copolymer for cancer cell-specific gene regulation systems. J Control Release 2009, 139:133-139.
    • (2009) J Control Release , vol.139 , pp. 133-139
    • Toita, R.1    Kang, J.H.2    Kim, J.H.3    Tomiyama, T.4    Mori, T.5    Niidome, T.6
  • 77
    • 67650684000 scopus 로고    scopus 로고
    • Protein kinase Cα polymeric carrier: its application for gene delivery into human cancers
    • Tomiyama T., Kang J.H., Toita R., Niidome T., Katayama Y. Protein kinase Cα polymeric carrier: its application for gene delivery into human cancers. Cancer Sci 2009, 100:1532-1536.
    • (2009) Cancer Sci , vol.100 , pp. 1532-1536
    • Tomiyama, T.1    Kang, J.H.2    Toita, R.3    Niidome, T.4    Katayama, Y.5
  • 78
    • 33845388144 scopus 로고    scopus 로고
    • Micellar nanocarriers: pharmaceutical perspectives
    • Torchilin V.P. Micellar nanocarriers: pharmaceutical perspectives. Pharm Res 2007, 24:1-16.
    • (2007) Pharm Res , vol.24 , pp. 1-16
    • Torchilin, V.P.1
  • 79
    • 34547121206 scopus 로고    scopus 로고
    • Hypoxia in cancer: significance and impact on clinical outcome
    • Vaupel P., Mayer A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 2007, 26:225-239.
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 225-239
    • Vaupel, P.1    Mayer, A.2
  • 80
    • 33747097252 scopus 로고    scopus 로고
    • Protein kinases and phosphatases as therapeutic targets in cancer
    • Ventura J.J., Nebreda A.R. Protein kinases and phosphatases as therapeutic targets in cancer. Clin Transl Oncol 2006, 8:153-160.
    • (2006) Clin Transl Oncol , vol.8 , pp. 153-160
    • Ventura, J.J.1    Nebreda, A.R.2
  • 81
    • 37049011374 scopus 로고    scopus 로고
    • Bacterial targeted tumour therapy-dawn of a new era
    • Wei M.Q., Mengesha A., Good D., Anné J. Bacterial targeted tumour therapy-dawn of a new era. Cancer Lett 2008, 18:16-27.
    • (2008) Cancer Lett , vol.18 , pp. 16-27
    • Wei, M.Q.1    Mengesha, A.2    Good, D.3    Anné, J.4
  • 82
    • 34447117505 scopus 로고    scopus 로고
    • Review: implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions
    • Wouters A., Pauwels B., Lardon F. Review: implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions. Oncologist 2007, 12:690-712.
    • (2007) Oncologist , vol.12 , pp. 690-712
    • Wouters, A.1    Pauwels, B.2    Lardon, F.3
  • 83
    • 10744221092 scopus 로고    scopus 로고
    • A novel small peptide as a targeting ligand of receptor tyrosine kinase Tie2
    • Wu X., Zhao R., Li Z. A novel small peptide as a targeting ligand of receptor tyrosine kinase Tie2. Biochem Biophys Res Commun 2004, 315:1004-1010.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 1004-1010
    • Wu, X.1    Zhao, R.2    Li, Z.3
  • 84
    • 0029150245 scopus 로고
    • Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size
    • Yuan F., Dellian M., Fukumura D., Leunig M., Berk D.A., Torchilin V.P., et al. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res 1995, 55:3752-3756.
    • (1995) Cancer Res , vol.55 , pp. 3752-3756
    • Yuan, F.1    Dellian, M.2    Fukumura, D.3    Leunig, M.4    Berk, D.A.5    Torchilin, V.P.6


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