메뉴 건너뛰기




Volumn 26, Issue 1, 2007, Pages 141-152

The folate receptor: What does it promise in tissue-targeted therapeutics?

Author keywords

Antifolate; Folate conjugate; Folate receptor; Immunotherapy; Tumor imaging; Tumor target

Indexed keywords

CARBOPLATIN; DEXAMETHASONE; DOXORUBICIN; FOLATE RECEPTOR; FOLATE RECEPTOR ALPHA; FOLATE RECEPTOR BETA; FOLIC ACID; FOLIC ACID ANTAGONIST; FOLIC ACID DERIVATIVE; FULVESTRANT; GELONIN; HISTONE DEACETYLASE INHIBITOR; ISOPROTEIN; LIPOSOME; LYMPHOCYTE ANTIBODY; NANOPARTICLE; PACLITAXEL; PENTETATE INDIUM IN 111; PENTETATE TECHNETIUM TC 99M; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE INHIBITOR; RADIOPHARMACEUTICAL AGENT; RETINOIC ACID; T LYMPHOCYTE RECEPTOR ANTIBODY; TAMOXIFEN; THYMIDYLATE SYNTHASE; THYMIDYLATE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 33947362046     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10555-007-9048-0     Document Type: Review
Times cited : (317)

References (125)
  • 1
    • 3142774934 scopus 로고    scopus 로고
    • Physiology of folate and vitamin B12 in health and disease
    • discussion S13
    • Stover, P. J. (2004). Physiology of folate and vitamin B12 in health and disease. Nutrition Reviews, 62, S3-S12, discussion S13.
    • (2004) Nutrition Reviews , vol.62
    • Stover, P.J.1
  • 6
    • 33751244559 scopus 로고    scopus 로고
    • Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
    • Qiu, A., Jansen, M., Sakaris, A., Min, S. H., Chattopadhyay, S., Tsai, E., et al. (2006). Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell, 127, 917-928.
    • (2006) Cell , vol.127 , pp. 917-928
    • Qiu, A.1    Jansen, M.2    Sakaris, A.3    Min, S.H.4    Chattopadhyay, S.5    Tsai, E.6
  • 7
    • 0026652116 scopus 로고
    • The biological chemistry of folate receptors
    • Antony, A. C. (1992). The biological chemistry of folate receptors. Blood, 79, 2807-2820.
    • (1992) Blood , vol.79 , pp. 2807-2820
    • Antony, A.C.1
  • 8
    • 1942535095 scopus 로고    scopus 로고
    • A review of folate receptor alpha cycling and 5-methyltetrahydrofolate accumulation with an emphasis on cell models in vitro
    • Kamen, B. A., & Smith, A. K. (2004). A review of folate receptor alpha cycling and 5-methyltetrahydrofolate accumulation with an emphasis on cell models in vitro. Advanced Drug Delivery Reviews, 56, 1085-1097.
    • (2004) Advanced Drug Delivery Reviews , vol.56 , pp. 1085-1097
    • Kamen, B.A.1    Smith, A.K.2
  • 9
    • 0032884078 scopus 로고    scopus 로고
    • Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development
    • Piedrahita, J. A., Oetama, B., Bennett, G. D., van Waes, J., Kamen, B. A., Richardson, J., et al. (1999). Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nature Genetics, 23, 228-232.
    • (1999) Nature Genetics , vol.23 , pp. 228-232
    • Piedrahita, J.A.1    Oetama, B.2    Bennett, G.D.3    van Waes, J.4    Kamen, B.A.5    Richardson, J.6
  • 10
    • 18344386053 scopus 로고    scopus 로고
    • Targeting therapeutic and imaging agents to folate receptor positive tumors
    • Reddy, J. A., Allagadda, V. M., & Leamon, C. P. (2005). Targeting therapeutic and imaging agents to folate receptor positive tumors. Current Pharmaceutical Biotechnology, 6, 131-150.
    • (2005) Current Pharmaceutical Biotechnology , vol.6 , pp. 131-150
    • Reddy, J.A.1    Allagadda, V.M.2    Leamon, C.P.3
  • 11
    • 1942503303 scopus 로고    scopus 로고
    • Distribution, functionality and gene regulation of folate receptor isoforms: Implications in targeted therapy
    • Elnakat, H., & Ratnam, M. (2004). Distribution, functionality and gene regulation of folate receptor isoforms: Implications in targeted therapy. Advanced Drug Delivery Reviews, 56, 1067-1084.
    • (2004) Advanced Drug Delivery Reviews , vol.56 , pp. 1067-1084
    • Elnakat, H.1    Ratnam, M.2
  • 12
    • 0028206803 scopus 로고
    • Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: CDNA cloning, expression, immunoreactivity, and tissue specificity
    • Shen, F., Ross, J. F., Wang, X., & Ratnam, M. (1994). Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity. Biochemistry, 33, 1209-1215.
    • (1994) Biochemistry , vol.33 , pp. 1209-1215
    • Shen, F.1    Ross, J.F.2    Wang, X.3    Ratnam, M.4
  • 13
    • 0034722715 scopus 로고    scopus 로고
    • Identification of two putative novel folate receptor genes in humans and mouse
    • Spiegelstein, O., Eudy, J. D., & Finnell, R. H. (2000). Identification of two putative novel folate receptor genes in humans and mouse. Gene, 258, 117-125.
    • (2000) Gene , vol.258 , pp. 117-125
    • Spiegelstein, O.1    Eudy, J.D.2    Finnell, R.H.3
  • 14
    • 0026481219 scopus 로고
    • Genomic organization of the human folate receptor genes on chromosome 11q13
    • Ragoussis, J., Senger, G., Trowsdale, J., & Campbell, I. G. (1992). Genomic organization of the human folate receptor genes on chromosome 11q13. Genomics, 14, 423-430.
    • (1992) Genomics , vol.14 , pp. 423-430
    • Ragoussis, J.1    Senger, G.2    Trowsdale, J.3    Campbell, I.G.4
  • 15
    • 0029022260 scopus 로고
    • Folate receptor type gamma is primarily a secretory protein due to lack of an efficient signal for glycosylphosphatidylinositol modification: Protein characterization and cell type specificity
    • Shen, F., Wu, M., Ross, J. F., Miller, D., & Ratnam, M. (1995). Folate receptor type gamma is primarily a secretory protein due to lack of an efficient signal for glycosylphosphatidylinositol modification: Protein characterization and cell type specificity. Biochemistry, 34, 5660-5665.
    • (1995) Biochemistry , vol.34 , pp. 5660-5665
    • Shen, F.1    Wu, M.2    Ross, J.F.3    Miller, D.4    Ratnam, M.5
  • 16
    • 0024336971 scopus 로고
    • Complementary DNA for the folate binding protein correctly predicts anchoring to the membrane by glycosyl-phosphatidylinositol
    • Lacey, S. W., Sanders, J. M., Rothberg, K. G., Anderson, R. G., & Kamen, B. A. (1989). Complementary DNA for the folate binding protein correctly predicts anchoring to the membrane by glycosyl-phosphatidylinositol. Journal of Clinical Investigation, 84, 715-720.
    • (1989) Journal of Clinical Investigation , vol.84 , pp. 715-720
    • Lacey, S.W.1    Sanders, J.M.2    Rothberg, K.G.3    Anderson, R.G.4    Kamen, B.A.5
  • 17
    • 0028867956 scopus 로고
    • Preferred sites of glycosylphosphatidylinositol modification in folate receptors and constraints in the primary structure of the hydrophobic portion of the signal
    • Yan, W., & Ratnam, M. (1995). Preferred sites of glycosylphosphatidylinositol modification in folate receptors and constraints in the primary structure of the hydrophobic portion of the signal. Biochemistry, 34, 14594-14600.
    • (1995) Biochemistry , vol.34 , pp. 14594-14600
    • Yan, W.1    Ratnam, M.2
  • 18
    • 0024791515 scopus 로고
    • A human membrane-associated folate binding protein is anchored by a glycosylphosphatidylinositol tail
    • Luhrs, C. A., & Slomiany, B. L. (1989). A human membrane-associated folate binding protein is anchored by a glycosylphosphatidylinositol tail. Journal of Biological Chemistry, 264, 21446-21449.
    • (1989) Journal of Biological Chemistry , vol.264 , pp. 21446-21449
    • Luhrs, C.A.1    Slomiany, B.L.2
  • 19
    • 0024476980 scopus 로고
    • Identification of a Mg2+-dependent protease in human placenta which cleaves hydrophobic folate-binding proteins to hydrophilic forms
    • Antony, A. C., Verma, R. S., Unune, A. R., & LaRosa, J. A. (1989). Identification of a Mg2+-dependent protease in human placenta which cleaves hydrophobic folate-binding proteins to hydrophilic forms. Journal of Biological Chemistry, 264, 1911-1914.
    • (1989) Journal of Biological Chemistry , vol.264 , pp. 1911-1914
    • Antony, A.C.1    Verma, R.S.2    Unune, A.R.3    LaRosa, J.A.4
  • 20
    • 0025740371 scopus 로고
    • The conversion of the human membrane-associated folate binding protein (folate receptor) to the soluble folate binding protein by a membrane-associated metalloprotease
    • Elwood, P. C., Deutsch, J. C., & Kolhouse, J. F. (1991). The conversion of the human membrane-associated folate binding protein (folate receptor) to the soluble folate binding protein by a membrane-associated metalloprotease. Journal of Biological Chemistry, 266, 2346-2353.
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 2346-2353
    • Elwood, P.C.1    Deutsch, J.C.2    Kolhouse, J.F.3
  • 21
    • 17544376275 scopus 로고    scopus 로고
    • Isolation and characterization of a folate receptor-directed metalloprotease from human placenta
    • Yang, X. Y., Mackins, J. Y., Li, Q. J., & Antony, A. C. (1996). Isolation and characterization of a folate receptor-directed metalloprotease from human placenta. Journal of Biological Chemistry, 271, 11493-11499.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 11493-11499
    • Yang, X.Y.1    Mackins, J.Y.2    Li, Q.J.3    Antony, A.C.4
  • 22
    • 0030694625 scopus 로고    scopus 로고
    • Proteolysis of the carboxyl-terminal GPI signal independent of GPI modification as a mechanism for selective protein secretion
    • Wang, J., Shen, F., Yan, W., Wu, M., & Ratnam, M. (1997). Proteolysis of the carboxyl-terminal GPI signal independent of GPI modification as a mechanism for selective protein secretion. Biochemistry, 36, 14583-14592.
    • (1997) Biochemistry , vol.36 , pp. 14583-14592
    • Wang, J.1    Shen, F.2    Yan, W.3    Wu, M.4    Ratnam, M.5
  • 23
    • 0024440701 scopus 로고
    • Homologous membrane folate binding proteins in human placenta: Cloning and sequence of a cDNA
    • Ratnam, M., Marquardt, H., Duhring, J. L., & Freisheim, J. H. (1989). Homologous membrane folate binding proteins in human placenta: Cloning and sequence of a cDNA. Biochemistry, 28, 8249-8254.
    • (1989) Biochemistry , vol.28 , pp. 8249-8254
    • Ratnam, M.1    Marquardt, H.2    Duhring, J.L.3    Freisheim, J.H.4
  • 24
    • 0030713346 scopus 로고    scopus 로고
    • Expression levels of functional folate receptors alpha and beta are related to the number of N-glycosylated sites
    • Shen, F., Wang, H., Zheng, X., & Ratnam, M. (1997). Expression levels of functional folate receptors alpha and beta are related to the number of N-glycosylated sites. Biochemical Journal, 327(Pt 3), 759-764.
    • (1997) Biochemical Journal , vol.327 , Issue.PART 3 , pp. 759-764
    • Shen, F.1    Wang, H.2    Zheng, X.3    Ratnam, M.4
  • 25
    • 0037372204 scopus 로고    scopus 로고
    • mRNA instability in the nucleus due to a novel open reading frame element is a major determinant of the narrow tissue specificity of folate receptor alpha
    • Zheng, X., Kelley, K., Elnakat, H., Yan, W., Dorn, T., & Ratnam, M. (2003). mRNA instability in the nucleus due to a novel open reading frame element is a major determinant of the narrow tissue specificity of folate receptor alpha. Molecular and Cellular Biology, 23, 2202-2212.
    • (2003) Molecular and Cellular Biology , vol.23 , pp. 2202-2212
    • Zheng, X.1    Kelley, K.2    Elnakat, H.3    Yan, W.4    Dorn, T.5    Ratnam, M.6
  • 26
    • 0026446685 scopus 로고
    • Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolates
    • Wang, X., Shen, F., Freisheim, J. H., Gentry, L. E., & Ratnam, M. (1992). Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolates. Biochemical Pharmacology, 44, 1898-1901.
    • (1992) Biochemical Pharmacology , vol.44 , pp. 1898-1901
    • Wang, X.1    Shen, F.2    Freisheim, J.H.3    Gentry, L.E.4    Ratnam, M.5
  • 27
    • 0033574661 scopus 로고    scopus 로고
    • Complete mapping of divergent amino acids responsible for differential ligand binding of folate receptors alpha and beta
    • Maziarz, K. M., Monaco, H. L., Shen, F., & Ratnam, M. (1999). Complete mapping of divergent amino acids responsible for differential ligand binding of folate receptors alpha and beta. Journal of Biological Chemistry, 274, 11086-11091.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 11086-11091
    • Maziarz, K.M.1    Monaco, H.L.2    Shen, F.3    Ratnam, M.4
  • 28
    • 0030952249 scopus 로고    scopus 로고
    • Crystal structure of chicken riboflavin-binding protein
    • Monaco, H. L. (1997). Crystal structure of chicken riboflavin-binding protein. EMBO Journal, 16, 1475-1483.
    • (1997) EMBO Journal , vol.16 , pp. 1475-1483
    • Monaco, H.L.1
  • 31
    • 0036232040 scopus 로고    scopus 로고
    • GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway
    • Sabharanjak, S., Sharma, P., Parton, R. G., & Mayor, S. (2002). GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway. Developmental Cell, 2, 411-423.
    • (2002) Developmental Cell , vol.2 , pp. 411-423
    • Sabharanjak, S.1    Sharma, P.2    Parton, R.G.3    Mayor, S.4
  • 33
    • 0030801644 scopus 로고    scopus 로고
    • Clustering of GPI-anchored folate receptor independent of both crosslinking and association with caveolin
    • Wu, M., Fan, J., Gunning, W., & Ratnam, M. (1997). Clustering of GPI-anchored folate receptor independent of both crosslinking and association with caveolin. Journal of Membrane Biology, 159, 137-147.
    • (1997) Journal of Membrane Biology , vol.159 , pp. 137-147
    • Wu, M.1    Fan, J.2    Gunning, W.3    Ratnam, M.4
  • 34
    • 0032552072 scopus 로고    scopus 로고
    • Microdomains of GPI-anchored proteins in living cells revealed by crosslinking
    • Friedrichson, T., & Kurzchalia, T. V. (1998). Microdomains of GPI-anchored proteins in living cells revealed by crosslinking. Nature, 394, 802-805.
    • (1998) Nature , vol.394 , pp. 802-805
    • Friedrichson, T.1    Kurzchalia, T.V.2
  • 35
    • 0032552054 scopus 로고    scopus 로고
    • GPI-anchored proteins are organized in submicron domains at the cell surface
    • Varma, R., & Mayor, S. (1998). GPI-anchored proteins are organized in submicron domains at the cell surface. Nature, 394, 798-801.
    • (1998) Nature , vol.394 , pp. 798-801
    • Varma, R.1    Mayor, S.2
  • 36
    • 0027503126 scopus 로고
    • Internalization and intracellular transport of folate-binding protein in rat kidney proximal tubule
    • Birn, H., Selhub, J., & Christensen, E. I. (1993). Internalization and intracellular transport of folate-binding protein in rat kidney proximal tubule. American Journal of Physiology, 264, C302-310.
    • (1993) American Journal of Physiology , vol.264
    • Birn, H.1    Selhub, J.2    Christensen, E.I.3
  • 38
    • 0032541423 scopus 로고    scopus 로고
    • Cholesterol-dependent retention of GPI-anchored proteins in endosomes
    • Mayor, S., Sabharanjak, S., & Maxfield, F. R. (1998). Cholesterol-dependent retention of GPI-anchored proteins in endosomes. EMBO Journal, 17, 4626-4638.
    • (1998) EMBO Journal , vol.17 , pp. 4626-4638
    • Mayor, S.1    Sabharanjak, S.2    Maxfield, F.R.3
  • 39
    • 0023683407 scopus 로고
    • Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles
    • Kamen, B. A., Wang, M. T., Streckfuss, A. J., Peryea, X., & Anderson, R. G. (1988). Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles. Journal of Biological Chemistry, 263, 13602-13609.
    • (1988) Journal of Biological Chemistry , vol.263 , pp. 13602-13609
    • Kamen, B.A.1    Wang, M.T.2    Streckfuss, A.J.3    Peryea, X.4    Anderson, R.G.5
  • 40
    • 0024454538 scopus 로고
    • Regulation of the cytoplasmic accumulation of 5-methyltetrahydrofolate in MA104 cells is independent of folate receptor regulation
    • Kamen, B. A., Johnson, C. A., Wang, M. T., & Anderson, R. G. (1989). Regulation of the cytoplasmic accumulation of 5-methyltetrahydrofolate in MA104 cells is independent of folate receptor regulation. Journal of Clinical Investigation, 84, 1379-1386.
    • (1989) Journal of Clinical Investigation , vol.84 , pp. 1379-1386
    • Kamen, B.A.1    Johnson, C.A.2    Wang, M.T.3    Anderson, R.G.4
  • 41
    • 0025303751 scopus 로고
    • The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway
    • Rothberg, K. G., Ying, Y. S., Kolhouse, J. F., Kamen, B. A., & Anderson, R. G. (1990). The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway. Journal of Cell Biology, 110, 637-649.
    • (1990) Journal of Cell Biology , vol.110 , pp. 637-649
    • Rothberg, K.G.1    Ying, Y.S.2    Kolhouse, J.F.3    Kamen, B.A.4    Anderson, R.G.5
  • 43
    • 0026625261 scopus 로고
    • Lowering the cholesterol content of MA104 cells inhibits receptor-mediated transport of folate
    • Chang, W. J., Rothberg, K. G., Kamen, B. A., & Anderson, R. G. (1992). Lowering the cholesterol content of MA104 cells inhibits receptor-mediated transport of folate. Journal of Cell Biology, 118, 63-69.
    • (1992) Journal of Cell Biology , vol.118 , pp. 63-69
    • Chang, W.J.1    Rothberg, K.G.2    Kamen, B.A.3    Anderson, R.G.4
  • 45
    • 0027280460 scopus 로고
    • Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells
    • Leamon, C. P., & Low, P. S. (1993). Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells. Biochemical Journal, 291(Pt 3), 855-860.
    • (1993) Biochemical Journal , vol.291 , Issue.PART 3 , pp. 855-860
    • Leamon, C.P.1    Low, P.S.2
  • 46
    • 0027436790 scopus 로고
    • Endocytosis of folate-protein conjugates: Ultrastructural localization in KB cells
    • Turek, J. J., Leamon, C. P., & Low, P. S. (1993). Endocytosis of folate-protein conjugates: Ultrastructural localization in KB cells. Journal of Cell Science, 106(Pt 1), 423-430.
    • (1993) Journal of Cell Science , vol.106 , Issue.PART 1 , pp. 423-430
    • Turek, J.J.1    Leamon, C.P.2    Low, P.S.3
  • 48
    • 0035135353 scopus 로고    scopus 로고
    • Folate-mediated targeting: From diagnostics to drug and gene delivery
    • Leamon, C. P., & Low, P. S. (2001). Folate-mediated targeting: From diagnostics to drug and gene delivery. Drug Discovery Today, 6, 44-51.
    • (2001) Drug Discovery Today , vol.6 , pp. 44-51
    • Leamon, C.P.1    Low, P.S.2
  • 49
    • 0023100453 scopus 로고
    • Characterization of human ovarian carcinoma-associated antigens defined by novel monoclonal antibodies with tumor-restricted specificity
    • Miotti, S., Canevari, S., Menard, S., Mezzanzanica, D., Porro, G., Pupa, S. M., et al. (1987). Characterization of human ovarian carcinoma-associated antigens defined by novel monoclonal antibodies with tumor-restricted specificity. International Journal of Cancer, 39, 297-303.
    • (1987) International Journal of Cancer , vol.39 , pp. 297-303
    • Miotti, S.1    Canevari, S.2    Menard, S.3    Mezzanzanica, D.4    Porro, G.5    Pupa, S.M.6
  • 50
    • 0026476410 scopus 로고
    • Cellular localization of the folate receptor: Potential role in drug toxicity and folate homeostasis
    • Weitman, S. D., Weinberg, A. G., Coney, L. R., Zurawski, V. R., Jennings, D. S., & Kamen, B. A. (1992). Cellular localization of the folate receptor: Potential role in drug toxicity and folate homeostasis. Cancer Research, 52, 6708-6711.
    • (1992) Cancer Research , vol.52 , pp. 6708-6711
    • Weitman, S.D.1    Weinberg, A.G.2    Coney, L.R.3    Zurawski, V.R.4    Jennings, D.S.5    Kamen, B.A.6
  • 51
    • 0034617083 scopus 로고    scopus 로고
    • Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium
    • Chancy, C. D., Kekuda, R., Huang, W., Prasad, P. D., Kuhnel, J. M., Sirotnak, F. M., et al. (2000). Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium. Journal of Biological Chemistry, 275, 20676-20684.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 20676-20684
    • Chancy, C.D.1    Kekuda, R.2    Huang, W.3    Prasad, P.D.4    Kuhnel, J.M.5    Sirotnak, F.M.6
  • 53
    • 0028301752 scopus 로고
    • Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications
    • Ross, J. F., Chaudhuri, P. K., & Ratnam, M. (1994). Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications. Cancer, 73, 2432-2443.
    • (1994) Cancer , vol.73 , pp. 2432-2443
    • Ross, J.F.1    Chaudhuri, P.K.2    Ratnam, M.3
  • 55
    • 0034914238 scopus 로고    scopus 로고
    • Novel patterns of gene expression in pituitary adenomas identified by complementary deoxyribonucleic acid microarrays and quantitative reverse transcription-polymerase chain reaction
    • Evans, C. O., Young, A. N., Brown, M. R., Brat, D. J., Parks, J. S., Neish, A. S., et al. (2001). Novel patterns of gene expression in pituitary adenomas identified by complementary deoxyribonucleic acid microarrays and quantitative reverse transcription-polymerase chain reaction. Journal of Clinical Endocrinology and Metabolism, 86, 3097-3107.
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , pp. 3097-3107
    • Evans, C.O.1    Young, A.N.2    Brown, M.R.3    Brat, D.J.4    Parks, J.S.5    Neish, A.S.6
  • 56
    • 0028148692 scopus 로고
    • The folate receptor in central nervous system malignancies of childhood
    • Weitman, S. D., Frazier, K. M., & Kamen, B. A. (1994). The folate receptor in central nervous system malignancies of childhood. Journal of Neuro-oncology, 21, 107-112.
    • (1994) Journal of Neuro-oncology , vol.21 , pp. 107-112
    • Weitman, S.D.1    Frazier, K.M.2    Kamen, B.A.3
  • 57
    • 0032883172 scopus 로고    scopus 로고
    • Expression of folate receptor type alpha in relation to cell type, malignancy, and differentiation in ovary, uterus, and cervix
    • Wu, M., Gunning, W., & Ratnam, M. (1999). Expression of folate receptor type alpha in relation to cell type, malignancy, and differentiation in ovary, uterus, and cervix. Cancer Epidemiology, Biomarkers & Prevention, 8, 775-782.
    • (1999) Cancer Epidemiology, Biomarkers & Prevention , vol.8 , pp. 775-782
    • Wu, M.1    Gunning, W.2    Ratnam, M.3
  • 59
    • 0038684626 scopus 로고    scopus 로고
    • Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodies
    • Figini, M., Ferri, R., Mezzanzanica, D., Bagnoli, M., Luison, E., Miotti, S., et al. (2003). Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodies. Gene Therapy, 10, 1018-1025.
    • (2003) Gene Therapy , vol.10 , pp. 1018-1025
    • Figini, M.1    Ferri, R.2    Mezzanzanica, D.3    Bagnoli, M.4    Luison, E.5    Miotti, S.6
  • 60
    • 0034670039 scopus 로고    scopus 로고
    • Differentiation-independent retinoid induction of folate receptor type beta, a potential tumor target in myeloid leukemia
    • Wang, H., Zheng, X., Behm, F. G., & Ratnam, M. (2000). Differentiation-independent retinoid induction of folate receptor type beta, a potential tumor target in myeloid leukemia. Blood, 96, 3529-3536.
    • (2000) Blood , vol.96 , pp. 3529-3536
    • Wang, H.1    Zheng, X.2    Behm, F.G.3    Ratnam, M.4
  • 61
    • 0032916448 scopus 로고    scopus 로고
    • Folate receptor type beta is a neutrophilic lineage marker and is differentially expressed in myeloid leukemia
    • Ross, J. F., Wang, H., Behm, F. G., Mathew, P., Wu, M., Booth, R., et al. (1999). Folate receptor type beta is a neutrophilic lineage marker and is differentially expressed in myeloid leukemia. Cancer, 85, 348-357.
    • (1999) Cancer , vol.85 , pp. 348-357
    • Ross, J.F.1    Wang, H.2    Behm, F.G.3    Mathew, P.4    Wu, M.5    Booth, R.6
  • 62
    • 0033152344 scopus 로고    scopus 로고
    • Expression and functional characterization of the beta-isoform of the folate receptor on CD34(+) cells
    • Reddy, J. A., Haneline, L. S., Srour, E. F., Antony, A. C., Clapp, D. W., & Low, P. S. (1999). Expression and functional characterization of the beta-isoform of the folate receptor on CD34(+) cells. Blood, 93, 3940-3948.
    • (1999) Blood , vol.93 , pp. 3940-3948
    • Reddy, J.A.1    Haneline, L.S.2    Srour, E.F.3    Antony, A.C.4    Clapp, D.W.5    Low, P.S.6
  • 63
    • 0033509413 scopus 로고    scopus 로고
    • Selective expression of folate receptor beta and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis
    • Nakashima-Matsushita, N., Homma, T., Yu, S., Matsuda, T., Sunahara, N., Nakamura, T., et al. (1999). Selective expression of folate receptor beta and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis. Arthritis and Rheumatism, 42, 1609-1616.
    • (1999) Arthritis and Rheumatism , vol.42 , pp. 1609-1616
    • Nakashima-Matsushita, N.1    Homma, T.2    Yu, S.3    Matsuda, T.4    Sunahara, N.5    Nakamura, T.6
  • 64
    • 0029149874 scopus 로고
    • Transduction of folate receptor cDNA into cervical carcinoma cells using recombinant adeno-associated virions delays cell proliferation in vitro and in vivo
    • Sun, X. L., Murphy, B. R., Li, Q. J., Gullapalli, S., Mackins, J., Jayaram, H. N., et al. (1995). Transduction of folate receptor cDNA into cervical carcinoma cells using recombinant adeno-associated virions delays cell proliferation in vitro and in vivo. Journal of Clinical Investigation, 96, 1535-1547.
    • (1995) Journal of Clinical Investigation , vol.96 , pp. 1535-1547
    • Sun, X.L.1    Murphy, B.R.2    Li, Q.J.3    Gullapalli, S.4    Mackins, J.5    Jayaram, H.N.6
  • 65
    • 0037100463 scopus 로고    scopus 로고
    • Strategy for the treatment of acute myelogenous leukemia based on folate receptor beta-targeted liposomal doxorubicin combined with receptor induction using all-trans retinoic acid
    • Pan, X. Q., Zheng, X., Shi, G., Wang, H., Ratnam, M., & Lee, R. J. (2002). Strategy for the treatment of acute myelogenous leukemia based on folate receptor beta-targeted liposomal doxorubicin combined with receptor induction using all-trans retinoic acid. Blood, 100, 594-602.
    • (2002) Blood , vol.100 , pp. 594-602
    • Pan, X.Q.1    Zheng, X.2    Shi, G.3    Wang, H.4    Ratnam, M.5    Lee, R.J.6
  • 66
    • 0029118446 scopus 로고
    • Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: Correlates of molecular-structure and biological activity
    • Westerhof, G. R., Schornagel, J. H., Kathmann, I., Jackman, A. L., Rosowsky, A., Forsch, R. A., et al. (1995). Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: Correlates of molecular-structure and biological activity. Molecular Pharmacology, 48, 459-471.
    • (1995) Molecular Pharmacology , vol.48 , pp. 459-471
    • Westerhof, G.R.1    Schornagel, J.H.2    Kathmann, I.3    Jackman, A.L.4    Rosowsky, A.5    Forsch, R.A.6
  • 67
    • 0037742256 scopus 로고    scopus 로고
    • Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the alpha-isoform of the folate receptor
    • Theti, D. S., Bavetsias, V., Skelton, L. A., Titley, J., Gibbs, D., Jansen, G., et al. (2003). Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the alpha-isoform of the folate receptor. Cancer Research, 63, 3612-3618.
    • (2003) Cancer Research , vol.63 , pp. 3612-3618
    • Theti, D.S.1    Bavetsias, V.2    Skelton, L.A.3    Titley, J.4    Gibbs, D.5    Jansen, G.6
  • 68
    • 0034081103 scopus 로고    scopus 로고
    • Design and synthesis of Cyclopenta[g]quinazoline- based antifolates as inhibitors of thymidylate synthase and potential antitumor agents
    • Bavetsias, V., Marriott, J. H., Melin, C., Kimbell, R., Matusiak, Z. S., Boyle, F. T., et al. (2000). Design and synthesis of Cyclopenta[g]quinazoline- based antifolates as inhibitors of thymidylate synthase and potential antitumor agents. Journal of Medicinal Chemistry, 43, 1910-1926.
    • (2000) Journal of Medicinal Chemistry , vol.43 , pp. 1910-1926
    • Bavetsias, V.1    Marriott, J.H.2    Melin, C.3    Kimbell, R.4    Matusiak, Z.S.5    Boyle, F.T.6
  • 69
    • 29244449017 scopus 로고    scopus 로고
    • BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors
    • Gibbs, D. D., Theti, D. S., Wood, N., Green, M., Raynaud, F., Valenti, M., et al. (2005). BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors. Cancer Research, 65, 11721-11728.
    • (2005) Cancer Research , vol.65 , pp. 11721-11728
    • Gibbs, D.D.1    Theti, D.S.2    Wood, N.3    Green, M.4    Raynaud, F.5    Valenti, M.6
  • 70
  • 71
    • 0036242840 scopus 로고    scopus 로고
    • Synthesis and evaluation of taxol-folic acid conjugates as targeted antineoplastics
    • Lee, J. W., Lu, J. Y., Low, P. S., & Fuchs, P. L. (2002). Synthesis and evaluation of taxol-folic acid conjugates as targeted antineoplastics. Bioorganic & Medicinal Chemistry, 10, 2397-2414.
    • (2002) Bioorganic & Medicinal Chemistry , vol.10 , pp. 2397-2414
    • Lee, J.W.1    Lu, J.Y.2    Low, P.S.3    Fuchs, P.L.4
  • 72
    • 0038246506 scopus 로고    scopus 로고
    • Folate-targeted PEG as a potential carrier for carboplatin analogs. Synthesis and in vitro studies
    • Aronov, O., Horowitz, A. T., Gabizon, A., & Gibson, D. (2003). Folate-targeted PEG as a potential carrier for carboplatin analogs. Synthesis and in vitro studies. Bioconjugate Chemistry, 14, 563-574.
    • (2003) Bioconjugate Chemistry , vol.14 , pp. 563-574
    • Aronov, O.1    Horowitz, A.T.2    Gabizon, A.3    Gibson, D.4
  • 73
    • 0035958878 scopus 로고    scopus 로고
    • Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells
    • Atkinson, S. F., Bettinger, T., Seymour, L. W., Behr, J. P., & Ward, C. M. (2001). Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells. Journal of Biological Chemistry, 276, 27930-27935.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 27930-27935
    • Atkinson, S.F.1    Bettinger, T.2    Seymour, L.W.3    Behr, J.P.4    Ward, C.M.5
  • 74
    • 0033625094 scopus 로고    scopus 로고
    • Synthesis of [(99m)Tc]DTPA-folate and its evaluation as a folate-receptor- targeted radiopharmaceutical
    • Mathias, C. J., Hubers, D., Low, P. S., & Green, M. A. (2000). Synthesis of [(99m)Tc]DTPA-folate and its evaluation as a folate-receptor- targeted radiopharmaceutical. Bioconjugate Chemistry, 11, 253-257.
    • (2000) Bioconjugate Chemistry , vol.11 , pp. 253-257
    • Mathias, C.J.1    Hubers, D.2    Low, P.S.3    Green, M.A.4
  • 76
    • 0030611096 scopus 로고    scopus 로고
    • Design and synthesis of [111In] DTPA-folate for use as a tumor-targeted radiopharmaceutical
    • Wang, S., Luo, J., Lantrip, D. A., Waters, D. J., Mathias, C. J., Green, M. A., et al. (1997). Design and synthesis of [111In] DTPA-folate for use as a tumor-targeted radiopharmaceutical. Bioconjugate Chemistry, 8, 673-679.
    • (1997) Bioconjugate Chemistry , vol.8 , pp. 673-679
    • Wang, S.1    Luo, J.2    Lantrip, D.A.3    Waters, D.J.4    Mathias, C.J.5    Green, M.A.6
  • 77
    • 0036862058 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of EC20: A new folate-derived, (99m)Tc-based radiopharmaceutical
    • Leamon, C. P., Parker, M. A., Vlahov, I. R., Xu, L. C., Reddy, J. A., Vetzel, M., et al. (2002). Synthesis and biological evaluation of EC20: A new folate-derived, (99m)Tc-based radiopharmaceutical. Bioconjugate Chemistry, 13, 1200-1210.
    • (2002) Bioconjugate Chemistry , vol.13 , pp. 1200-1210
    • Leamon, C.P.1    Parker, M.A.2    Vlahov, I.R.3    Xu, L.C.4    Reddy, J.A.5    Vetzel, M.6
  • 78
    • 2642514921 scopus 로고    scopus 로고
    • Preclinical evaluation of (99m)Tc-EC20 for imaging folate receptor-positive tumors
    • Reddy, J. A., Xu, L. C., Parker, N., Vetzel, M., & Leamon, C. P. (2004). Preclinical evaluation of (99m)Tc-EC20 for imaging folate receptor-positive tumors. Journal of Nuclear Medicine, 45, 857-866.
    • (2004) Journal of Nuclear Medicine , vol.45 , pp. 857-866
    • Reddy, J.A.1    Xu, L.C.2    Parker, N.3    Vetzel, M.4    Leamon, C.P.5
  • 79
    • 0032588840 scopus 로고    scopus 로고
    • 99mTc-HYNICfolate: A novel receptor-based targeted radiopharmaceutical for tumor imaging
    • Guo, W., Hinkle, G. H., & Lee, R. J. (1999). 99mTc-HYNICfolate: A novel receptor-based targeted radiopharmaceutical for tumor imaging. Journal of Nuclear Medicine, 40, 1563-1569.
    • (1999) Journal of Nuclear Medicine , vol.40 , pp. 1563-1569
    • Guo, W.1    Hinkle, G.H.2    Lee, R.J.3
  • 80
    • 0030019317 scopus 로고    scopus 로고
    • Synthesis, purification, and tumor cell uptake of 67Ga-deferoxamine- folate, a potential radiopharmaceutical for tumor imaging
    • Wang, S., Lee, R. J., Mathias, C. J., Green, M. A., & Low, P. S. (1996). Synthesis, purification, and tumor cell uptake of 67Ga-deferoxamine- folate, a potential radiopharmaceutical for tumor imaging. Bioconjugate Chemistry, 7, 56-62.
    • (1996) Bioconjugate Chemistry , vol.7 , pp. 56-62
    • Wang, S.1    Lee, R.J.2    Mathias, C.J.3    Green, M.A.4    Low, P.S.5
  • 81
    • 0032892065 scopus 로고    scopus 로고
    • Receptor-mediated targeting of 67Ga-deferoxamine-folate to folate-receptor-positive human KB tumor xenografts
    • Mathias, C. J., Wang, S., Low, P. S., Waters, D. J., & Green, M. A. (1999). Receptor-mediated targeting of 67Ga-deferoxamine-folate to folate-receptor-positive human KB tumor xenografts. Nuclear Medicine and Biology, 26, 23-25.
    • (1999) Nuclear Medicine and Biology , vol.26 , pp. 23-25
    • Mathias, C.J.1    Wang, S.2    Low, P.S.3    Waters, D.J.4    Green, M.A.5
  • 82
    • 0035999173 scopus 로고    scopus 로고
    • Synthesis and evaluation of 99mTc(CO) (3)-DTPA-folate as a folate-receptor-targeted radiopharmaceutical
    • Trump, D. P., Mathias, C. J., Yang, Z., Low, P. S., Marmion, M., & Green, M. A. (2002). Synthesis and evaluation of 99mTc(CO) (3)-DTPA-folate as a folate-receptor-targeted radiopharmaceutical. Nuclear Medicine and Biology, 29, 569-573.
    • (2002) Nuclear Medicine and Biology , vol.29 , pp. 569-573
    • Trump, D.P.1    Mathias, C.J.2    Yang, Z.3    Low, P.S.4    Marmion, M.5    Green, M.A.6
  • 83
  • 84
    • 0038621645 scopus 로고    scopus 로고
    • Evaluation of 111In-DTPA-folate as a receptor-targeted diagnostic agent for ovarian cancer: Initial clinical results
    • Siegel, B. A., Dehdashti, F., Mutch, D. G., Podoloff, D. A., Wendt, R., Sutton, G. P., et al. (2003). Evaluation of 111In-DTPA-folate as a receptor-targeted diagnostic agent for ovarian cancer: Initial clinical results. Journal of Nuclear Medicine, 44, 700-707.
    • (2003) Journal of Nuclear Medicine , vol.44 , pp. 700-707
    • Siegel, B.A.1    Dehdashti, F.2    Mutch, D.G.3    Podoloff, D.A.4    Wendt, R.5    Sutton, G.P.6
  • 85
    • 0028001056 scopus 로고
    • Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis
    • Lee, R. J., & Low, P. S. (1994). Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis. Journal of Biological Chemistry, 269, 3198-3204.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 3198-3204
    • Lee, R.J.1    Low, P.S.2
  • 86
    • 0028794831 scopus 로고
    • Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro
    • Lee, R. J., & Low, P. S. (1995). Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro. Biochimica et Biophysica Acta, 1233, 134-144.
    • (1995) Biochimica et Biophysica Acta , vol.1233 , pp. 134-144
    • Lee, R.J.1    Low, P.S.2
  • 87
    • 0037335188 scopus 로고    scopus 로고
    • Antitumor activity of folate receptor-targeted liposomal doxorubicin in a KB oral carcinoma murine xenograft model
    • Pan, X. Q., Wang, H., & Lee, R. J. (2003). Antitumor activity of folate receptor-targeted liposomal doxorubicin in a KB oral carcinoma murine xenograft model. Pharmaceutical Research, 20, 417-422.
    • (2003) Pharmaceutical Research , vol.20 , pp. 417-422
    • Pan, X.Q.1    Wang, H.2    Lee, R.J.3
  • 88
    • 0034031080 scopus 로고    scopus 로고
    • Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump
    • Goren, D., Horowitz, A. T., Tzemach, D., Tarshish, M., Zalipsky, S., & Gabizon, A. (2000). Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump. Clinical Cancer Research, 6, 1949-1957.
    • (2000) Clinical Cancer Research , vol.6 , pp. 1949-1957
    • Goren, D.1    Horowitz, A.T.2    Tzemach, D.3    Tarshish, M.4    Zalipsky, S.5    Gabizon, A.6
  • 89
    • 0028924955 scopus 로고
    • Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol
    • Wang, S., Lee, R. J., Cauchon, G., Gorenstein, D. G., & Low, P. S. (1995). Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol. Proceedings of the National Academy of Sciences of the United States of America, 92, 3318-3322.
    • (1995) Proceedings of the National Academy of Sciences of the United States of America , vol.92 , pp. 3318-3322
    • Wang, S.1    Lee, R.J.2    Cauchon, G.3    Gorenstein, D.G.4    Low, P.S.5
  • 90
    • 0029932762 scopus 로고    scopus 로고
    • Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer
    • Lee, R. J., & Huang, L. (1996). Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer. Journal of Biological Chemistry, 271, 8481-8487.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 8481-8487
    • Lee, R.J.1    Huang, L.2
  • 91
    • 0036738537 scopus 로고    scopus 로고
    • Incorporation of reversibly cross-linked polyplexes into LPDII vectors for gene delivery
    • Gosselin, M. A., Guo, W., & Lee, R. J. (2002). Incorporation of reversibly cross-linked polyplexes into LPDII vectors for gene delivery. Bioconjugate Chemistry, 13, 1044-1053.
    • (2002) Bioconjugate Chemistry , vol.13 , pp. 1044-1053
    • Gosselin, M.A.1    Guo, W.2    Lee, R.J.3
  • 92
    • 1942439013 scopus 로고    scopus 로고
    • Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid-PEG conjugates
    • Gabizon, A., Shmeeda, H., Horowitz, A. T., & Zalipsky, S. (2004). Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid-PEG conjugates. Advanced Drug Delivery Reviews, 56, 1177-1192.
    • (2004) Advanced Drug Delivery Reviews , vol.56 , pp. 1177-1192
    • Gabizon, A.1    Shmeeda, H.2    Horowitz, A.T.3    Zalipsky, S.4
  • 93
    • 0038116522 scopus 로고    scopus 로고
    • Folateliposome-mediated antisense oligodeoxynucleotide targeting to cancer cells: Evaluation in vitro and in vivo
    • Leamon, C. P., Cooper, S. R., & Hardee, G. E. (2003). Folateliposome-mediated antisense oligodeoxynucleotide targeting to cancer cells: Evaluation in vitro and in vivo. Bioconjugate Chemistry, 14, 738-747.
    • (2003) Bioconjugate Chemistry , vol.14 , pp. 738-747
    • Leamon, C.P.1    Cooper, S.R.2    Hardee, G.E.3
  • 94
    • 0033971786 scopus 로고    scopus 로고
    • Enhanced folate receptor mediated gene therapy using a novel pH-sensitive lipid formulation
    • Reddy, J. A., & Low, P. S. (2000). Enhanced folate receptor mediated gene therapy using a novel pH-sensitive lipid formulation. Journal of Controlled Release, 64, 27-37.
    • (2000) Journal of Controlled Release , vol.64 , pp. 27-37
    • Reddy, J.A.1    Low, P.S.2
  • 95
    • 4544266019 scopus 로고    scopus 로고
    • Iron oxide nanoparticles as magnetic resonance contrast agent for tumor imaging via folate receptor-targeted delivery
    • Choi, H., Choi, S. R., Zhou, R., Kung, H. F., & Chen, I. W. (2004). Iron oxide nanoparticles as magnetic resonance contrast agent for tumor imaging via folate receptor-targeted delivery. Academic Radiology, 11, 996-1004.
    • (2004) Academic Radiology , vol.11 , pp. 996-1004
    • Choi, H.1    Choi, S.R.2    Zhou, R.3    Kung, H.F.4    Chen, I.W.5
  • 96
    • 25444482796 scopus 로고    scopus 로고
    • Folate-conjugated iron oxide nanoparticles for solid tumor targeting as potential specific magnetic hyperthermia mediators: Synthesis, physicochemical characterization, and in vitro experiments
    • Sonvico, F., Mornet, S., Vasseur, S., Dubernet, C., Jaillard, D., Degrouard, J., et al. (2005). Folate-conjugated iron oxide nanoparticles for solid tumor targeting as potential specific magnetic hyperthermia mediators: Synthesis, physicochemical characterization, and in vitro experiments. Bioconjugate Chemistry, 16, 1181-1188.
    • (2005) Bioconjugate Chemistry , vol.16 , pp. 1181-1188
    • Sonvico, F.1    Mornet, S.2    Vasseur, S.3    Dubernet, C.4    Jaillard, D.5    Degrouard, J.6
  • 97
    • 23844533668 scopus 로고    scopus 로고
    • 64Cu-labeled folate-conjugated shell cross-linked nanoparticles for tumor imaging and radiotherapy: Synthesis, radiolabeling, and biologic evaluation
    • Rossin, R., Pan, D., Qi, K., Turner, J. L., Sun, X., Wooley, K. L., et al. (2005). 64Cu-labeled folate-conjugated shell cross-linked nanoparticles for tumor imaging and radiotherapy: Synthesis, radiolabeling, and biologic evaluation. Journal of Nuclear Medicine, 46, 1210-1218.
    • (2005) Journal of Nuclear Medicine , vol.46 , pp. 1210-1218
    • Rossin, R.1    Pan, D.2    Qi, K.3    Turner, J.L.4    Sun, X.5    Wooley, K.L.6
  • 99
    • 23844477204 scopus 로고    scopus 로고
    • Folate-receptor-mediated delivery of InP quantum dots for bioimaging using confocal and two-photon microscopy
    • Bharali, D. J., Lucey, D. W., Jayakumar, H., Pudavar, H. E., & Prasad, P. N. (2005). Folate-receptor-mediated delivery of InP quantum dots for bioimaging using confocal and two-photon microscopy. Journal of the American Chemical Society, 127, 11364-11371.
    • (2005) Journal of the American Chemical Society , vol.127 , pp. 11364-11371
    • Bharali, D.J.1    Lucey, D.W.2    Jayakumar, H.3    Pudavar, H.E.4    Prasad, P.N.5
  • 101
    • 29144450682 scopus 로고    scopus 로고
    • Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents
    • Zheng, G., Chen, J., Li, H., & Glickson, J. D. (2005). Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents. Proceedings of the National Academy of Sciences of the United States of America, 102, 17757-17762.
    • (2005) Proceedings of the National Academy of Sciences of the United States of America , vol.102 , pp. 17757-17762
    • Zheng, G.1    Chen, J.2    Li, H.3    Glickson, J.D.4
  • 102
    • 0026329982 scopus 로고
    • Cloning of a tumor-associated antigen: MOv18 and MOv19 antibodies recognize a folate-binding protein
    • Coney, L. R., Tomassetti, A., Carayannopoulos, L., Frasca, V., Kamen, B. A., Colnaghi, M. I., et al. (1991). Cloning of a tumor-associated antigen: MOv18 and MOv19 antibodies recognize a folate-binding protein. Cancer Research, 51, 6125-6132.
    • (1991) Cancer Research , vol.51 , pp. 6125-6132
    • Coney, L.R.1    Tomassetti, A.2    Carayannopoulos, L.3    Frasca, V.4    Kamen, B.A.5    Colnaghi, M.I.6
  • 104
    • 0031780611 scopus 로고    scopus 로고
    • Targeting T cells against brain tumors with a bispecific ligand-antibody conjugate
    • Roy, E. J., Cho, B. K., Rund, L. A., Patrick, T. A., & Kranz, D. M. (1998). Targeting T cells against brain tumors with a bispecific ligand-antibody conjugate. International Journal of Cancer, 76, 761-766.
    • (1998) International Journal of Cancer , vol.76 , pp. 761-766
    • Roy, E.J.1    Cho, B.K.2    Rund, L.A.3    Patrick, T.A.4    Kranz, D.M.5
  • 105
    • 0036219732 scopus 로고    scopus 로고
    • Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors
    • Lu, Y., & Low, P. S. (2002). Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors. Cancer Immunology and Immunotherapy, 51, 153-162.
    • (2002) Cancer Immunology and Immunotherapy , vol.51 , pp. 153-162
    • Lu, Y.1    Low, P.S.2
  • 108
    • 0033852105 scopus 로고    scopus 로고
    • Calicheamicin-conjugated humanized anti-CD33 monoclonal antibody (gemtuzumab zogamicin, CMA-676) shows cytocidal effect on CD33-positive leukemia cell lines, but is inactive on P-glycoprotein-expressing sublines
    • Naito, K., Takeshita, A., Shigeno, K., Nakamura, S., Fujisawa, S., Shinjo, K., et al. (2000). Calicheamicin-conjugated humanized anti-CD33 monoclonal antibody (gemtuzumab zogamicin, CMA-676) shows cytocidal effect on CD33-positive leukemia cell lines, but is inactive on P-glycoprotein-expressing sublines. Leukemia, 14, 1436-1443.
    • (2000) Leukemia , vol.14 , pp. 1436-1443
    • Naito, K.1    Takeshita, A.2    Shigeno, K.3    Nakamura, S.4    Fujisawa, S.5    Shinjo, K.6
  • 109
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker, B. J., Talpaz, M., Resta, D. J., Peng, B., Buchdunger, E., Ford, J. M., et al. (2001). Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. New England Journal of Medicine, 344, 1031-1037.
    • (2001) New England Journal of Medicine , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3    Peng, B.4    Buchdunger, E.5    Ford, J.M.6
  • 111
    • 0035103315 scopus 로고    scopus 로고
    • Therapy of human T-cell acute lymphoblastic leukaemia with a combination of anti-CD7 and anti-CD38-SAPORIN immunotoxins is significantly better than therapy with each individual immunotoxin
    • Flavell, D. J., Boehm, D. A., Noss, A., Warnes, S. L., & Flavell, S. U. (2001). Therapy of human T-cell acute lymphoblastic leukaemia with a combination of anti-CD7 and anti-CD38-SAPORIN immunotoxins is significantly better than therapy with each individual immunotoxin. British Journal of Cancer, 84, 571-578.
    • (2001) British Journal of Cancer , vol.84 , pp. 571-578
    • Flavell, D.J.1    Boehm, D.A.2    Noss, A.3    Warnes, S.L.4    Flavell, S.U.5
  • 113
    • 0031850006 scopus 로고    scopus 로고
    • Humanized M195 monoclonal antibody conjugated to recombinant gelonin: An anti-CD33 immunotoxin with antileukemic activity
    • Pagliaro, L. C., Liu, B., Munker, R., Andreeff, M., Freireich, E. J., Scheinberg, D. A., et al. (1998). Humanized M195 monoclonal antibody conjugated to recombinant gelonin: An anti-CD33 immunotoxin with antileukemic activity. Clinical Cancer Research, 4, 1971-1976.
    • (1998) Clinical Cancer Research , vol.4 , pp. 1971-1976
    • Pagliaro, L.C.1    Liu, B.2    Munker, R.3    Andreeff, M.4    Freireich, E.J.5    Scheinberg, D.A.6
  • 114
    • 0030921452 scopus 로고    scopus 로고
    • Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells
    • Kreitman, R. J., & Pastan, I. (1997). Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells. Blood, 90, 252-259.
    • (1997) Blood , vol.90 , pp. 252-259
    • Kreitman, R.J.1    Pastan, I.2
  • 115
    • 0033379879 scopus 로고    scopus 로고
    • In vitro cellular accumulation and cytotoxicity of liposomal and conventional formulations of daunorubicin and doxorubicin in resistant K562 cells
    • Wang, Y., Eksborg, S., Lewensohn, R., Lindberg, A., & Liliemark, E. (1999). In vitro cellular accumulation and cytotoxicity of liposomal and conventional formulations of daunorubicin and doxorubicin in resistant K562 cells. Anti-cancer Drugs, 10, 921-928.
    • (1999) Anti-cancer Drugs , vol.10 , pp. 921-928
    • Wang, Y.1    Eksborg, S.2    Lewensohn, R.3    Lindberg, A.4    Liliemark, E.5
  • 116
    • 0030294102 scopus 로고    scopus 로고
    • Enhanced delivery of synthetic oligonucleotides to human leukaemic cells by liposomes and immunoliposomes
    • Ma, D. D., & Wei, A. Q. (1996). Enhanced delivery of synthetic oligonucleotides to human leukaemic cells by liposomes and immunoliposomes. Leukemia Research, 20, 925-930.
    • (1996) Leukemia Research , vol.20 , pp. 925-930
    • Ma, D.D.1    Wei, A.Q.2
  • 117
    • 0034214039 scopus 로고    scopus 로고
    • Selective targeting of immunoliposomal doxorubicin against human multiple myeloma in vitro and ex vivo
    • Lopes de Menezes, D. E., Pilarski, L. M., Belch, A. R., & Allen, T. M. (2000). Selective targeting of immunoliposomal doxorubicin against human multiple myeloma in vitro and ex vivo. Biochimica et Biophysica Acta, 1466, 205-220.
    • (2000) Biochimica et Biophysica Acta , vol.1466 , pp. 205-220
    • Lopes de Menezes, D.E.1    Pilarski, L.M.2    Belch, A.R.3    Allen, T.M.4
  • 118
    • 0030983406 scopus 로고    scopus 로고
    • Modulation of doxorubicin resistance in a doxorubicin-resistant human leukaemia cell by an immunoliposome targeting transferring receptor
    • Suzuki, S., Inoue, K., Hongoh, A., Hashimoto, Y., & Yamazoe, Y. (1997). Modulation of doxorubicin resistance in a doxorubicin-resistant human leukaemia cell by an immunoliposome targeting transferring receptor. British Journal of Cancer, 76, 83-89.
    • (1997) British Journal of Cancer , vol.76 , pp. 83-89
    • Suzuki, S.1    Inoue, K.2    Hongoh, A.3    Hashimoto, Y.4    Yamazoe, Y.5
  • 119
    • 0027298342 scopus 로고
    • Cytotoxicity of adriamycin-containing immunoliposomes targeted with anti-ganglioside monoclonal antibodies
    • Ohta, S., Igarashi, S., Honda, A., Sato, S., & Hanai, N. (1993). Cytotoxicity of adriamycin-containing immunoliposomes targeted with anti-ganglioside monoclonal antibodies. Anticancer Research, 13, 331-336.
    • (1993) Anticancer Research , vol.13 , pp. 331-336
    • Ohta, S.1    Igarashi, S.2    Honda, A.3    Sato, S.4    Hanai, N.5
  • 120
    • 0038615895 scopus 로고    scopus 로고
    • Modulation of the folate receptor alpha gene by the estrogen receptor: Mechanism and implications in tumor targeting
    • Kelley, K. M., Rowan, B. G., & Ratnam, M. (2003). Modulation of the folate receptor alpha gene by the estrogen receptor: Mechanism and implications in tumor targeting. Cancer Research, 63, 2820-2828.
    • (2003) Cancer Research , vol.63 , pp. 2820-2828
    • Kelley, K.M.1    Rowan, B.G.2    Ratnam, M.3
  • 121
    • 20144371873 scopus 로고    scopus 로고
    • Enhancement of folate receptor alpha expression in tumor cells through the glucocorticoid receptor: A promising means to improved tumor detection and targeting
    • Tran, T., Shatnawi, A., Zheng, X., Kelley, K. M., & Ratnam, M. (2005). Enhancement of folate receptor alpha expression in tumor cells through the glucocorticoid receptor: A promising means to improved tumor detection and targeting. Cancer Research, 65, 4431-4441.
    • (2005) Cancer Research , vol.65 , pp. 4431-4441
    • Tran, T.1    Shatnawi, A.2    Zheng, X.3    Kelley, K.M.4    Ratnam, M.5
  • 122
    • 0037789606 scopus 로고    scopus 로고
    • Modulation of the folate receptor type beta gene by coordinate actions of retinoic acid receptors at activator Sp1/ets and repressor AP-1 sites
    • Hao, H., Qi, H., & Ratnam, M. (2003). Modulation of the folate receptor type beta gene by coordinate actions of retinoic acid receptors at activator Sp1/ets and repressor AP-1 sites. Blood, 101, 4551-4560.
    • (2003) Blood , vol.101 , pp. 4551-4560
    • Hao, H.1    Qi, H.2    Ratnam, M.3
  • 123
    • 33745280074 scopus 로고    scopus 로고
    • Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: Mechanism and utility in enhancing selective growth inhibition by antifolates
    • Qi, H., & Ratnam, M. (2006). Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: Mechanism and utility in enhancing selective growth inhibition by antifolates. Cancer Research, 66, 5875-5882.
    • (2006) Cancer Research , vol.66 , pp. 5875-5882
    • Qi, H.1    Ratnam, M.2
  • 124
    • 0031889953 scopus 로고    scopus 로고
    • Membrane receptors for endocytosis in the renal proximal tubule
    • Christensen, E. I., Birn, H., Verroust, P., & Moestrup, S. K. (1998) Membrane receptors for endocytosis in the renal proximal tubule. Int. Rev. Cytol., 180, 237-284.
    • (1998) Int. Rev. Cytol , vol.180 , pp. 237-284
    • Christensen, E.I.1    Birn, H.2    Verroust, P.3    Moestrup, S.K.4
  • 125
    • 0028001056 scopus 로고
    • Delivery of liposomes into cultured KB cells via Folate receptor-mediated endocytosis
    • Lee, R. J., & Low, P. S. (1994) Delivery of liposomes into cultured KB cells via Folate receptor-mediated endocytosis. J. Biol. Chem. 269, 3198-3204.
    • (1994) J. Biol. Chem , vol.269 , pp. 3198-3204
    • Lee, R.J.1    Low, P.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.