Hepatoma-targeted gene delivery using a tumor cell-specific gene regulation system combined with a human liver cell-specific bionanocapsule

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 6, Issue 4, 2010, Pages 583-589

  Kang, Jeong Hun ^a   Oishi, Jun ^a   Kim, Jong Hwan ^b   Ijuin, Moeko ^a   Toita, Riki ^a   Jun, Byungdug ^b   Asai, Daisuke ^c   Mori, Takeshi ^a   Niidome, Takuro ^a   Tanizawa, Katsuyuki ^d   Kuroda, Shun'ichi ^d   Katayama, Yoshiki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

^c ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Gene delivery; Hepatocellular carcinoma; Intracellular signal; Protein kinase

Indexed keywords

GENE DELIVERY; GENE DELIVERY SYSTEMS; GENE REGULATIONS; HEPATOCELLULAR CARCINOMA; HEPATOMA CELLS; HUMAN HEPATOCYTES; HUMAN LIVER CELLS; IN-CELL; INTRACELLULAR SIGNALS; MALIGNANT TUMORS; MOLECULAR IMAGING; PROTEIN KINASE; PROTEIN KINASE C; SELECTIVE TREATMENT; SIDE EFFECT; SURVIVAL RATE; TARGETED GENE DELIVERY; TRANSFECTION EFFICIENCY; TREATMENT EFFICIENCY; TUMOR CELLS;

CELLS; CYTOLOGY; GENE EXPRESSION; GENE TRANSFER; HISTOLOGY; LIVER; NUCLEIC ACIDS; POLYMERS; PROTEINS; TUMORS;

GENE THERAPY;

DNA; MACROGOL; N METHACRYLOYL POLYETHYLENE GLYCOL; NANOCAPSULE; PROTEIN KINASE C ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GENE THERAPY; CELL SPECIFICITY; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; GENE DELIVERY SYSTEM; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC TRANSFECTION; LIVER CELL CARCINOMA; MALE; MOLECULAR IMAGING; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL;

ANIMALS; CARCINOMA, HEPATOCELLULAR; GENE EXPRESSION REGULATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; HEPATOCYTES; HUMANS; LIVER; LIVER NEOPLASMS; MALE; MICE; NANOCAPSULES; OLIGOPEPTIDES; TUMOR CELLS, CULTURED;

EID: 77955281517     PISSN: 15499634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nano.2010.01.007     Document Type: Article

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