Protein kinase Cα-specific peptide substrate graft-type copolymer for cancer cell-specific gene regulation systems

Journal of Controlled Release

Volumn 139, Issue 2, 2009, Pages 133-139

  Toita, Riki ^a   Kang, Jeong Hun ^a,b   Kim, Jong Hwan ^c   Tomiyama, Tetsuro ^a   Mori, Takeshi ^a   Niidome, Takuro ^a   Jun, Byungdug ^c   Katayama, Yoshiki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b Advanced Medical Engineering Center   (Japan)

^c NAGASAKI UNIVERSITY   (Japan)

Author keywords

Gene regulation; Kinase responsive polymer; Protein kinase C

Indexed keywords

CANCER CELLS; CATIONIC COPOLYMER; CATIONIC PEPTIDES; GENE REGULATION; GENE REGULATIONS; GENE SUPPRESSION; IN-CELL; INTRACELLULAR ENZYME; KINASE-RESPONSIVE POLYMER; MAIN CHAINS; NEUTRAL POLYMERS; PEPTIDE SUBSTRATES; PHOSPHORYLATION REACTIONS; PHOSPHORYLATION SITES; POLY-L-LYSINE; PROTEIN KINASE C; SERINE RESIDUES; SIDE CHAINS; STERIC HINDRANCES; SUBSTRATE PEPTIDES; TRANSGENE EXPRESSION; TRANSGENE REGULATION; TUMOR CELLS; TUMOR GENE THERAPY;

AMINES; AMINO ACIDS; CELL MEMBRANES; CHEMICAL REACTIONS; COPOLYMERS; DYES; GENE EXPRESSION; GENETIC ENGINEERING; ORGANIC POLYMERS; PEPTIDES; PHOSPHORYLATION; PLASTIC PRODUCTS; POLYMERS; SUBSTRATES; TUMORS;

COPOLYMERIZATION;

ALANINE; COPOLYMER; PLASMID DNA; POLYLYSINE; PROTEIN KINASE C ALPHA; SERINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL SPECIFICITY; COMPLEX FORMATION; CONTROLLED STUDY; DNA DRUG COMPLEX; ENZYME ACTIVATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC TRANSFECTION; HYDROPHILICITY; MALE; MOLECULAR RECOGNITION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSGENE; ZETA POTENTIAL;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; DNA; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE THERAPY; MALE; MELANOMA; MICE; MICE, INBRED BALB C; PEPTIDES; PLASMIDS; POLYLYSINE; PROTEIN KINASE C-ALPHA; TRANSFECTION;

EID: 69949137270     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.06.011     Document Type: Article

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