The development of MDA-7/IL-24 as a cancer therapeutic

Pharmacology and Therapeutics

Volumn 128, Issue 2, 2010, Pages 375-384

  Dent, Paul ^a   Yacoub, Adly ^a   Hamed, Hossein A ^a   Park, Margaret A ^a   Dash, Rupesh ^a   Bhutia, Sujit K ^a   Sarkar, Devanand ^a   Wang, Xiang Yang ^a   Gupta, Pankaj ^a   Emdad, Luni ^e   Lebedeva, Irina V ^f   Sauane, Moira ^f   Su, Zhao zhong ^a   Rahmani, Mohamed ^b   Broaddus, William C ^a   Young, Harold F ^a   Lesniak, Maciej S ^d   Grant, Steven ^a,b   Curiel, David T ^c   Fisher, Paul B ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f NONE   (United States)

Author keywords

Apoptosis; Autophagy; Ca2+; Ceramide; Clinical trial; ER stress; IL 24; MCL 1; MDA 7; PERK; ROS; Signal transduction

Indexed keywords

BECLIN 1; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2; INTERLEUKIN 24; PROTEIN KINASE R;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AUTOPHAGY; CANCER CELL; CANCER RADIOTHERAPY; CANCER THERAPY; CYTOLOGY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; INTRACELLULAR SIGNALING; KIDNEY CANCER; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN BINDING; PROTEIN EXPRESSION; RADIOSENSITIZATION; REVIEW; SUBTRACTIVE HYBRIDIZATION; TUMOR CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIFFERENTIATION; DRUG DISCOVERY; HUMANS; INTERLEUKINS; MELANOMA; SIGNAL TRANSDUCTION;

EID: 77957017185     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2010.08.001     Document Type: Review

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